2E2IL

Rna polymerase ii elongation complex in 5 mm mg+2 with 2'-dgtp
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2e2iL00
5IYDL 5IP9L 3GTQL 5IP7L 3GTPL 1K83L 3CQZL 2NVQL 1TWHL 2E2HL 4X6AL 4BXXL 3RZOL 2NVYL 2R7ZL 3FKIL 4QIWP 5FJ8L 3HOVL 4BBRL 4A3FL 2JA8L 3GTML 3S16L 1TWCL 2PMZP 4A3ML 3S15L 4A3CL 3S1NL 3H0GL 2VUML 4Y7NL 3S2DL 3S2HL 4A3DL 4C3JL 4A3GL 5IYCL 1I6HL 3HOUL 4A93L 3I4ML 4BY7L 5C44L 3I4NL 5M3ML 3S17L 3H3VM 4A3JL 3RZDL 5FLML 5M5YL 3GTGL 5IYBL 3PO2L 4A3IL 2B63L 5C4XL 3GTLL 2E2JL 2JA6L 3HOYL 5M5WL 2R92L 3GTOL 1Y1WL 2NVTL 1WCML 4A3EL 2E2IL 2Y0SP 1Y1VL 3HOZL 3HOXL 2YU9L 3M4OL 2JA7L 3S1ML 4A3KL 3S14L 2WB1P 4C3HL 1TWFL 1TWGL 2R93L 4Y52L 4C3IL 5C4JL 3PO3L 2NVXL 3K7AL 3HKZP 5C3EL 3M3YL 1TWAL 1I3QL 4A3BL 1R9TL 4AYBP 3S1RL 4BY1L 3HOWL 4C2M1 2WAQP 3S1QL 1SFOL 4BBSL 3GTKL 2JA5L 1I50L 3GTJL 4A3LL 5M5XL 5M3FL
chains in the Genus database with same CATH superfamily
1R0HA 2O5JD 3KYXA 4JADA 2AYJA 1NXEA 1RYQA 1YK5A 4BXXL 1IU5A 2NVYL 2R7ZL 2A69D 3FKIL 4POGA 4LHLA 3S16L 4BBRL 2JA8L 2PMZP 3VPBE 3PL5A 3S2DL 5MF6A 4A3DL 4C3JL 1WJVA 2M4VA 1RWDA 4GS7D 3HOUL 4XXBB 3I4ML 2K2DA 3LNLA 5M3ML 3S17L 1FHMA 2XJTA 3PIO1 4AR5A 1C09A 3RZDL 5M5YL 1BFYA 4TPUA 2V0EA 3H97A 3KYVA 4A3IL 2B63L 2MS3A 1LKPA 2JA6L 5GAGc 3HOYL 3P8BA 2Z3RB 2R92L 2L0ZA 5GAHc 3RZTA 3HOZL 2A6HD 5MLC3 3MQKB 1CADA 3PWFA 5RXNA 2JI2A 2WB1P 1S30A 4ME3A 1IW7D 1P7PA 3SS2A 2M6OA 4AHWA 1TWAL 2KKDA 4AYBP 4U671 1B13A 2XJQA 1BQ8A 1YUXA 1SMWA 1SFOL 4JAGA 2JI1A 2EY4E 5M5XL 2AQCA 2RDVA 3KYUA 4JAFA 1B2OA 1H7VA 3CQZL 5IY0A 2NVQL 2CKCA 4X6AL 5AI2A 2RFKB 1QYBA 4YWMA 1S2ZA 2BE5D 3LWRB 1ZRPA 3IU3I 4E6YA 4AHXA 4QIWP 4LHNA 1TWCL 1RYTA 3S15L 4A3CL 4V196 3MSUA 2CKAA 3J7Y1 2VUML 4AI3A 2J9UB 2M6PA 5IYCL 1PFYA 4A93L 1OWBA 2KN9A 5C44L 2XJPA 3HJYB 1T9PA 3LWPB 3HJWB 1T9QA 1FHHA 5GAEc 3B0AB 3H3VM 4A3JL 5FLML 1Z92B 3GTGL 1PZXA 3GTLL 2AUSB 3ZG6A 3PKJA 1IU6A 2NVTL 1WCML 4A3EL 2LCQA 1SMUA 2YU9L 2JA7L 1R0GA 4A3KL 2DSXA 4AHYA 3LWOB 1BRFA 1RB9A 3K7AL 1R0JA 3P2AA 4A3BL 1R9TL 4AR4A 4BY1L 3B08B 3RYGA 3S1RL 5AN9H 3HOWL 2H12A 1RDVA 3S1QL 5K2ME 3H9BA 1R0IA 3GTKL 2VL6A 5M3FL 5IYDL 5EINC 5IP9L 3GTQL 4TVMA 1DX8A 1NXGA 1ODHA 5IP7L 5MFZA 2PSMC 3HAXC 2GMGA 3J7Z1 1BQ9A 2XJSA 8RXNA 3RZOL 1PFVA 3FDJA 3H9CA 5FJ8L 4A3FL 4POFA 3LPEB 4WFN1 4Y7NL 2PYAA 1CAAA 2Z3QB 4A3GL 1IROA 1I6HL 4BY7L 1OWCA 4RXNA 5H1Sc 3LWQB 3JR7A 1LKOA 2ERJA 5IYBL 4YWLA 3PO2L 4XGHA 5C4XL 2E2JL 2ZIXA 2JI3A 5M5WL 2CR8A 6RXNA 3GTOL 1Y1WL 1YV1A 3KYYA 2E2IL 2Y0SP 4AI1A 1Y1VL 1YK4A 2M4YA 5DM61 3RZ6A 2A6ED 2V3BB 1IRNA 3S14L 3PZAA 1TWGL 2NYDA 3MPSA 1JYBA 4AR3A 5MFPA 4G6BA 5C4JL 3PO3L 3NFPI 2NVXL 5AI3A 3HKZP 5C3EL 1VZIA 1R0FA 3M3YL 1VZHA 1PFUA 1I3QL 1S24A 5DM71 2B5ID 1YUZA 2WAQP 1B2JA 4BBSL 1BE7A 2HR5A 3H99A 2ERSA 3K35A 3PKIA 1B71A 3PIP1 2C6AA 3GTPL 1K83L 5JVH1 4JAEA 2PPTA 3LWVB 1TWHL 2E2HL 4AI2A 4K9FA 1PFWA 4UY81 3A44A 3HOVL 3GTML 3WWNB 1F4LA 4A3ML 3QQCE 3WWLA 3S1NL 3H0GL 1RDGA 3S2HL 1E8JA 1LTLA 1DVBA 3I4NL 1QCVA 2HVYC 3KYWA 4ZN1B 5MGNA 1SMMA 7RXNA 4AHZA 4ZN3B 2XJRA 5GADc 5EIOC 1VZGA 1QQTA 3HOXL 4AI0A 3M4OL 3S1ML 2QL0A 4C3HL 1TWFL 2R93L 4Y52L 4AR6A 4C3IL 1VCXA 2XJVA 2XJUA 1LKMA 2C6BA 2PVXA 5JVG1 2A68D 3QVDA 1NNQA 4C2M1 4B8CD 2APOB 1T9OA 2JA5L 1I50L 3GTJL 2PVEA 4A3LL 2V0FA
chains in the Genus database with same CATH topology
5IYDL 5IP9L 3GTQL 5IP7L 3GTPL 1K83L 3CQZL 2NVQL 1TWHL 2E2HL 4X6AL 4BXXL 3RZOL 2NVYL 2R7ZL 3FKIL 4QIWP 5FJ8L 3HOVL 4BBRL 4A3FL 2JA8L 3GTML 3S16L 1TWCL 2PMZP 4A3ML 3S15L 4A3CL 3S1NL 3H0GL 2VUML 4Y7NL 3S2DL 3S2HL 4A3DL 4C3JL 4A3GL 5IYCL 1I6HL 3HOUL 4A93L 3I4ML 4BY7L 5C44L 3I4NL 5M3ML 3S17L 3H3VM 4A3JL 3RZDL 5FLML 5M5YL 3GTGL 5IYBL 3PO2L 4A3IL 2B63L 5C4XL 3GTLL 2E2JL 2JA6L 3HOYL 5M5WL 2R92L 3GTOL 1Y1WL 2NVTL 1WCML 4A3EL 2E2IL 2Y0SP 1Y1VL 3HOZL 3HOXL 2YU9L 3M4OL 2JA7L 3S1ML 4A3KL 3S14L 2WB1P 4C3HL 1TWFL 1TWGL 2R93L 4Y52L 4C3IL 5C4JL 3PO3L 2NVXL 3K7AL 3HKZP 5C3EL 3M3YL 1TWAL 1I3QL 4A3BL 1R9TL 4AYBP 3S1RL 4BY1L 3HOWL 4C2M1 2WAQP 3S1QL 1SFOL 4BBSL 3GTKL 2JA5L 1I50L 3GTJL 4A3LL 5M5XL 5M3FL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IYD L;  5IP9 L;  3GTQ L;  5IP7 L;  3GTP L;  1K83 L;  3CQZ L;  2NVQ L;  1TWH L;  2E2H L;  4X6A L;  4BXX L;  3RZO L;  2NVY L;  2R7Z L;  3FKI L;  4QIW P;  5FJ8 L;  3HOV L;  4BBR L;  4A3F L;  2JA8 L;  3GTM L;  3S16 L;  1TWC L;  2PMZ P;  4A3M L;  3S15 L;  4A3C L;  3S1N L;  3H0G L;  2VUM L;  4Y7N L;  3S2D L;  3S2H L;  4A3D L;  4C3J L;  4A3G L;  5IYC L;  1I6H L;  3HOU L;  4A93 L;  3I4M L;  4BY7 L;  5C44 L;  3I4N L;  5M3M L;  3S17 L;  3H3V M;  4A3J L;  3RZD L;  5FLM L;  5M5Y L;  3GTG L;  5IYB L;  3PO2 L;  4A3I L;  2B63 L;  5C4X L;  3GTL L;  2E2J L;  2JA6 L;  3HOY L;  5M5W L;  2R92 L;  3GTO L;  1Y1W L;  2NVT L;  1WCM L;  4A3E L;  2E2I L;  2Y0S P;  1Y1V L;  3HOZ L;  3HOX L;  2YU9 L;  3M4O L;  2JA7 L;  3S1M L;  4A3K L;  3S14 L;  2WB1 P;  4C3H L;  1TWF L;  1TWG L;  2R93 L;  4Y52 L;  4C3I L;  5C4J L;  3PO3 L;  2NVX L;  3K7A L;  3HKZ P;  5C3E L;  3M3Y L;  1TWA L;  1I3Q L;  4A3B L;  1R9T L;  4AYB P;  3S1R L;  4BY1 L;  3HOW L;  4C2M 1;  2WAQ P;  3S1Q L;  1SFO L;  4BBS L;  3GTK L;  2JA5 L;  1I50 L;  3GTJ L;  4A3L L;  5M5X L;  5M3F L; 
#chains in the Genus database with same CATH topology
 1R0H A;  2O5J D;  3KYX A;  4JAD A;  2AYJ A;  1NXE A;  1RYQ A;  1YK5 A;  4BXX L;  1IU5 A;  2NVY L;  2R7Z L;  2A69 D;  3FKI L;  4POG A;  4LHL A;  3S16 L;  4BBR L;  2JA8 L;  2PMZ P;  3VPB E;  3PL5 A;  3S2D L;  5MF6 A;  4A3D L;  4C3J L;  1WJV A;  2M4V A;  1RWD A;  4GS7 D;  3HOU L;  4XXB B;  3I4M L;  2K2D A;  3LNL A;  5M3M L;  3S17 L;  1FHM A;  2XJT A;  3PIO 1;  4AR5 A;  1C09 A;  3RZD L;  5M5Y L;  1BFY A;  4TPU A;  2V0E A;  3H97 A;  3KYV A;  4A3I L;  2B63 L;  2MS3 A;  1LKP A;  2JA6 L;  5GAG c;  3HOY L;  3P8B A;  2Z3R B;  2R92 L;  2L0Z A;  5GAH c;  3RZT A;  3HOZ L;  2A6H D;  5MLC 3;  3MQK B;  1CAD A;  3PWF A;  5RXN A;  2JI2 A;  2WB1 P;  1S30 A;  4ME3 A;  1IW7 D;  1P7P A;  3SS2 A;  2M6O A;  4AHW A;  1TWA L;  2KKD A;  4AYB P;  4U67 1;  1B13 A;  2XJQ A;  1BQ8 A;  1YUX A;  1SMW A;  1SFO L;  4JAG A;  2JI1 A;  2EY4 E;  5M5X L;  2AQC A;  2RDV A;  3KYU A;  4JAF A;  1B2O A;  1H7V A;  3CQZ L;  5IY0 A;  2NVQ L;  2CKC A;  4X6A L;  5AI2 A;  2RFK B;  1QYB A;  4YWM A;  1S2Z A;  2BE5 D;  3LWR B;  1ZRP A;  3IU3 I;  4E6Y A;  4AHX A;  4QIW P;  4LHN A;  1TWC L;  1RYT A;  3S15 L;  4A3C L;  4V19 6;  3MSU A;  2CKA A;  3J7Y 1;  2VUM L;  4AI3 A;  2J9U B;  2M6P A;  5IYC L;  1PFY A;  4A93 L;  1OWB A;  2KN9 A;  5C44 L;  2XJP A;  3HJY B;  1T9P A;  3LWP B;  3HJW B;  1T9Q A;  1FHH A;  5GAE c;  3B0A B;  3H3V M;  4A3J L;  5FLM L;  1Z92 B;  3GTG L;  1PZX A;  3GTL L;  2AUS B;  3ZG6 A;  3PKJ A;  1IU6 A;  2NVT L;  1WCM L;  4A3E L;  2LCQ A;  1SMU A;  2YU9 L;  2JA7 L;  1R0G A;  4A3K L;  2DSX A;  4AHY A;  3LWO B;  1BRF A;  1RB9 A;  3K7A L;  1R0J A;  3P2A A;  4A3B L;  1R9T L;  4AR4 A;  4BY1 L;  3B08 B;  3RYG A;  3S1R L;  5AN9 H;  3HOW L;  2H12 A;  1RDV A;  3S1Q L;  5K2M E;  3H9B A;  1R0I A;  3GTK L;  2VL6 A;  5M3F L;  5IYD L;  5EIN C;  5IP9 L;  3GTQ L;  4TVM A;  1DX8 A;  1NXG A;  1ODH A;  5IP7 L;  5MFZ A;  2PSM C;  3HAX C;  2GMG A;  3J7Z 1;  1BQ9 A;  2XJS A;  8RXN A;  3RZO L;  1PFV A;  3FDJ A;  3H9C A;  5FJ8 L;  4A3F L;  4POF A;  3LPE B;  4WFN 1;  4Y7N L;  2PYA A;  1CAA A;  2Z3Q B;  4A3G L;  1IRO A;  1I6H L;  4BY7 L;  1OWC A;  4RXN A;  5H1S c;  3LWQ B;  3JR7 A;  1LKO A;  2ERJ A;  5IYB L;  4YWL A;  3PO2 L;  4XGH A;  5C4X L;  2E2J L;  2ZIX A;  2JI3 A;  5M5W L;  2CR8 A;  6RXN A;  3GTO L;  1Y1W L;  1YV1 A;  3KYY A;  2E2I L;  2Y0S P;  4AI1 A;  1Y1V L;  1YK4 A;  2M4Y A;  5DM6 1;  3RZ6 A;  2A6E D;  2V3B B;  1IRN A;  3S14 L;  3PZA A;  1TWG L;  2NYD A;  3MPS A;  1JYB A;  4AR3 A;  5MFP A;  4G6B A;  5C4J L;  3PO3 L;  3NFP I;  2NVX L;  5AI3 A;  3HKZ P;  5C3E L;  1VZI A;  1R0F A;  3M3Y L;  1VZH A;  1PFU A;  1I3Q L;  1S24 A;  5DM7 1;  2B5I D;  1YUZ A;  2WAQ P;  1B2J A;  4BBS L;  1BE7 A;  2HR5 A;  3H99 A;  2ERS A;  3K35 A;  3PKI A;  1B71 A;  3PIP 1;  2C6A A;  3GTP L;  1K83 L;  5JVH 1;  4JAE A;  2PPT A;  3LWV B;  1TWH L;  2E2H L;  4AI2 A;  4K9F A;  1PFW A;  4UY8 1;  3A44 A;  3HOV L;  3GTM L;  3WWN B;  1F4L A;  4A3M L;  3QQC E;  3WWL A;  3S1N L;  3H0G L;  1RDG A;  3S2H L;  1E8J A;  1LTL A;  1DVB A;  3I4N L;  1QCV A;  2HVY C;  3KYW A;  4ZN1 B;  5MGN A;  1SMM A;  7RXN A;  4AHZ A;  4ZN3 B;  2XJR A;  5GAD c;  5EIO C;  1VZG A;  1QQT A;  3HOX L;  4AI0 A;  3M4O L;  3S1M L;  2QL0 A;  4C3H L;  1TWF L;  2R93 L;  4Y52 L;  4AR6 A;  4C3I L;  1VCX A;  2XJV A;  2XJU A;  1LKM A;  2C6B A;  2PVX A;  5JVG 1;  2A68 D;  3QVD A;  1NNQ A;  4C2M 1;  4B8C D;  2APO B;  1T9O A;  2JA5 L;  1I50 L;  3GTJ L;  2PVE A;  4A3L L;  2V0F A; 
#chains in the Genus database with same CATH homology
 5IYD L;  5IP9 L;  3GTQ L;  5IP7 L;  3GTP L;  1K83 L;  3CQZ L;  2NVQ L;  1TWH L;  2E2H L;  4X6A L;  4BXX L;  3RZO L;  2NVY L;  2R7Z L;  3FKI L;  4QIW P;  5FJ8 L;  3HOV L;  4BBR L;  4A3F L;  2JA8 L;  3GTM L;  3S16 L;  1TWC L;  2PMZ P;  4A3M L;  3S15 L;  4A3C L;  3S1N L;  3H0G L;  2VUM L;  4Y7N L;  3S2D L;  3S2H L;  4A3D L;  4C3J L;  4A3G L;  5IYC L;  1I6H L;  3HOU L;  4A93 L;  3I4M L;  4BY7 L;  5C44 L;  3I4N L;  5M3M L;  3S17 L;  3H3V M;  4A3J L;  3RZD L;  5FLM L;  5M5Y L;  3GTG L;  5IYB L;  3PO2 L;  4A3I L;  2B63 L;  5C4X L;  3GTL L;  2E2J L;  2JA6 L;  3HOY L;  5M5W L;  2R92 L;  3GTO L;  1Y1W L;  2NVT L;  1WCM L;  4A3E L;  2E2I L;  2Y0S P;  1Y1V L;  3HOZ L;  3HOX L;  2YU9 L;  3M4O L;  2JA7 L;  3S1M L;  4A3K L;  3S14 L;  2WB1 P;  4C3H L;  1TWF L;  1TWG L;  2R93 L;  4Y52 L;  4C3I L;  5C4J L;  3PO3 L;  2NVX L;  3K7A L;  3HKZ P;  5C3E L;  3M3Y L;  1TWA L;  1I3Q L;  4A3B L;  1R9T L;  4AYB P;  3S1R L;  4BY1 L;  3HOW L;  4C2M 1;  2WAQ P;  3S1Q L;  1SFO L;  4BBS L;  3GTK L;  2JA5 L;  1I50 L;  3GTJ L;  4A3L L;  5M5X L;  5M3F L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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