2E2JL

Rna polymerase ii elongation complex in 5 mm mg+2 with gmpcpp
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3'
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2e2jL00
5IP7L 4BY1L 2NVTL 5M3ML 3GTML 3CQZL 3RZDL 5C4XL 1TWGL 2JA7L 4BXXL 3GTKL 1WCML 4A3GL 3FKIL 3I4NL 1TWAL 3H0GL 1SFOL 3GTQL 2Y0SP 1Y1WL 4A3CL 5FLML 3S2DL 2PMZP 5IYCL 4QIWP 3S17L 4A3IL 2VUML 1I50L 3S14L 5IP9L 4C3JL 4C3IL 4A3ML 4Y52L 1TWHL 1TWCL 4A93L 5IYDL 4A3FL 1R9TL 1I6HL 2WAQP 2JA8L 3H3VM 4X6AL 3HOWL 3GTJL 4A3JL 4A3DL 5FJ8L 2NVXL 2NVYL 5M5WL 3HOXL 3HOUL 4A3BL 2WB1P 3PO3L 1K83L 5C44L 2E2JL 3HOVL 3S1ML 4A3LL 4BBRL 3HOYL 3GTOL 4Y7NL 3GTGL 2YU9L 2NVQL 3S16L 3M3YL 2JA5L 3HKZP 2R92L 2E2HL 3S1NL 3S1RL 4A3EL 2B63L 4BBSL 3HOZL 2R93L 4AYBP 3S15L 2E2IL 3M4OL 5C3EL 4BY7L 2JA6L 4C2M1 4C3HL 1I3QL 3GTPL 5M3FL 5C4JL 3RZOL 3S2HL 3K7AL 3I4ML 3GTLL 3PO2L 5IYBL 5M5XL 1TWFL 4A3KL 2R7ZL 1Y1VL 5M5YL 3S1QL
chains in the Genus database with same CATH superfamily
1IROA 2PSMC 5IP7L 1H7VA 2PVXA 5RXNA 3LWVB 3CQZL 5C4XL 4U671 2VL6A 4BXXL 4A3GL 1S2ZA 2M4YA 5DM71 4AI3A 1WJVA 4A3CL 5AI2A 5IYCL 2XJTA 1PFYA 2PVEA 5K2ME 2RFKB 3LPEB 3PIO1 4XGHA 3SS2A 2A68D 5H1Sc 4C3JL 3RYGA 5MGNA 5EINC 2JI2A 1ODHA 5AI3A 4LHLA 5MFZA 4A93L 4B8CD 2KKDA 1R9TL 1I6HL 4X6AL 1QCVA 3GTJL 2NVYL 5M5WL 2AUSB 2XJUA 3VPBE 2E2JL 1F4LA 2B5ID 3S1ML 5JVG1 4AHZA 2AYJA 4UY81 4BBRL 2QL0A 3JR7A 3M3YL 5GAHc 2JA5L 1BQ8A 2E2HL 3S1RL 4A3EL 3H97A 2PYAA 2XJVA 1VZHA 3M4OL 1PFVA 5C3EL 4BY7L 2A69D 1I3QL 5M3FL 5C4JL 2J9UB 3PKJA 4GS7D 1R0GA 1IU5A 1NNQA 5M5XL 4YWMA 1OWBA 2A6HD 2HVYC 3KYUA 4BY1L 3QVDA 3GTML 3RZDL 2XJPA 2V0EA 2XJRA 2JA7L 2JI3A 3GTKL 2Z3RB 4RXNA 1PZXA 1SMMA 1IW7D 1RB9A 1CAAA 3I4NL 4JAEA 4AR4A 1TWAL 3LWQB 3KYVA 1R0IA 3GTQL 1T9QA 2Y0SP 4TPUA 4AR6A 1NXGA 1P7PA 3S2DL 4QIWP 1S24A 2ZIXA 3RZ6A 6RXNA 3FDJA 4A3ML 4C3IL 3MQKB 1VZIA 3NFPI 1T9OA 4ZN3B 2PPTA 1SMUA 3PWFA 1LKOA 4A3DL 2NVXL 4A3BL 2WB1P 4AHXA 2CR8A 3P2AA 1K83L 3HOVL 2Z3QB 1DX8A 2C6AA 2RDVA 7RXNA 2M4VA 3GTGL 2YU9L 3S16L 1R0HA 1Z92B 3HKZP 3HOZL 4G6BA 3PKIA 2R93L 5JVH1 4V196 3WWLA 2JA6L 4C2M1 3B08B 4AI1A 3GTLL 2LCQA 2KN9A 2BE5D 3KYXA 2NYDA 8RXNA 1RWDA 2M6PA 4A3KL 5GADc 5MLC3 4AHYA 1NXEA 2NVTL 1BQ9A 3PIP1 3H99A 1TWGL 5GAEc 1WCML 4WFN1 3WWNB 3H0GL 2H12A 2CKAA 4YWLA 1RYQA 2JI1A 1YK5A 1B2JA 3S17L 2MS3A 4A3IL 4K9FA 2VUML 1LTLA 1B71A 1TWHL 1TWCL 1LKMA 3ZG6A 3HJWB 4A3FL 1OWCA 1B13A 1RDGA 2WAQP 2JA8L 3A44A 2DSXA 3HOXL 3HOUL 3MPSA 1E8JA 2APOB 3HOYL 3GTOL 2AQCA 4JAGA 2R92L 2C6BA 4BBSL 4ME3A 3LWOB 3S15L 2E2IL 4C3HL 3GTPL 3RZOL 3KYYA 4AR5A 3LWRB 3PO2L 4XXBB 1C09A 5IYBL 2GMGA 1TWFL 1BRFA 2R7ZL 1IU6A 3S1QL 3LNLA 4AI0A 3J7Y1 1FHHA 2CKCA 1YUXA 2K2DA 5M3ML 1YK4A 4POGA 3PL5A 4E6YA 1RDVA 3J7Z1 3FKIL 3K35A 3LWPB 2L0ZA 3IU3I 1SFOL 1R0JA 5IY0A 1Y1WL 5AN9H 5GAGc 4JADA 1VZGA 5FLML 2PMZP 2V0FA 5MF6A 4LHNA 1PFUA 1QYBA 4JAFA 1I50L 4AR3A 1QQTA 1S30A 1FHMA 2V3BB 4POFA 3S14L 5IP9L 4Y52L 1YV1A 1ZRPA 3B0AB 3HAXC 3KYWA 5IYDL 5EIOC 3H9CA 3H3VM 1R0FA 3HOWL 4A3JL 1DVBA 1BFYA 5FJ8L 2M6OA 1YUZA 5DM61 3PO3L 3RZTA 5C44L 3PZAA 4ZN1B 2O5JD 1RYTA 2A6ED 2ERJA 4A3LL 4Y7NL 1VCXA 2NVQL 1JYBA 1T9PA 2XJQA 3MSUA 3S1NL 2EY4E 2B63L 1BE7A 4AYBP 3QQCE 3H9BA 1LKPA 3HJYB 3P8BA 4AHWA 1PFWA 3S2HL 3K7AL 3I4ML 2XJSA 1CADA 2ERSA 4TVMA 4AI2A 1SMWA 1B2OA 2HR5A 1IRNA 1Y1VL 5M5YL 5MFPA
chains in the Genus database with same CATH topology
5IP7L 4BY1L 2NVTL 5M3ML 3GTML 3CQZL 3RZDL 5C4XL 1TWGL 2JA7L 4BXXL 3GTKL 1WCML 4A3GL 3FKIL 3I4NL 1TWAL 3H0GL 1SFOL 3GTQL 2Y0SP 1Y1WL 4A3CL 5FLML 3S2DL 2PMZP 5IYCL 4QIWP 3S17L 4A3IL 2VUML 1I50L 3S14L 5IP9L 4C3JL 4C3IL 4A3ML 4Y52L 1TWHL 1TWCL 4A93L 5IYDL 4A3FL 1R9TL 1I6HL 2WAQP 2JA8L 3H3VM 4X6AL 3HOWL 3GTJL 4A3JL 4A3DL 5FJ8L 2NVXL 2NVYL 5M5WL 3HOXL 3HOUL 4A3BL 2WB1P 3PO3L 1K83L 5C44L 2E2JL 3HOVL 3S1ML 4A3LL 4BBRL 3HOYL 3GTOL 4Y7NL 3GTGL 2YU9L 2NVQL 3S16L 3M3YL 2JA5L 3HKZP 2R92L 2E2HL 3S1NL 3S1RL 4A3EL 2B63L 4BBSL 3HOZL 2R93L 4AYBP 3S15L 2E2IL 3M4OL 5C3EL 4BY7L 2JA6L 4C2M1 4C3HL 1I3QL 3GTPL 5M3FL 5C4JL 3RZOL 3S2HL 3K7AL 3I4ML 3GTLL 3PO2L 5IYBL 5M5XL 1TWFL 4A3KL 2R7ZL 1Y1VL 5M5YL 3S1QL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IP7 L;  4BY1 L;  2NVT L;  5M3M L;  3GTM L;  3CQZ L;  3RZD L;  5C4X L;  1TWG L;  2JA7 L;  4BXX L;  3GTK L;  1WCM L;  4A3G L;  3FKI L;  3I4N L;  1TWA L;  3H0G L;  1SFO L;  3GTQ L;  2Y0S P;  1Y1W L;  4A3C L;  5FLM L;  3S2D L;  2PMZ P;  5IYC L;  4QIW P;  3S17 L;  4A3I L;  2VUM L;  1I50 L;  3S14 L;  5IP9 L;  4C3J L;  4C3I L;  4A3M L;  4Y52 L;  1TWH L;  1TWC L;  4A93 L;  5IYD L;  4A3F L;  1R9T L;  1I6H L;  2WAQ P;  2JA8 L;  3H3V M;  4X6A L;  3HOW L;  3GTJ L;  4A3J L;  4A3D L;  5FJ8 L;  2NVX L;  2NVY L;  5M5W L;  3HOX L;  3HOU L;  4A3B L;  2WB1 P;  3PO3 L;  1K83 L;  5C44 L;  2E2J L;  3HOV L;  3S1M L;  4A3L L;  4BBR L;  3HOY L;  3GTO L;  4Y7N L;  3GTG L;  2YU9 L;  2NVQ L;  3S16 L;  3M3Y L;  2JA5 L;  3HKZ P;  2R92 L;  2E2H L;  3S1N L;  3S1R L;  4A3E L;  2B63 L;  4BBS L;  3HOZ L;  2R93 L;  4AYB P;  3S15 L;  2E2I L;  3M4O L;  5C3E L;  4BY7 L;  2JA6 L;  4C2M 1;  4C3H L;  1I3Q L;  3GTP L;  5M3F L;  5C4J L;  3RZO L;  3S2H L;  3K7A L;  3I4M L;  3GTL L;  3PO2 L;  5IYB L;  5M5X L;  1TWF L;  4A3K L;  2R7Z L;  1Y1V L;  5M5Y L;  3S1Q L; 
#chains in the Genus database with same CATH topology
 1IRO A;  2PSM C;  5IP7 L;  1H7V A;  2PVX A;  5RXN A;  3LWV B;  3CQZ L;  5C4X L;  4U67 1;  2VL6 A;  4BXX L;  4A3G L;  1S2Z A;  2M4Y A;  5DM7 1;  4AI3 A;  1WJV A;  4A3C L;  5AI2 A;  5IYC L;  2XJT A;  1PFY A;  2PVE A;  5K2M E;  2RFK B;  3LPE B;  3PIO 1;  4XGH A;  3SS2 A;  2A68 D;  5H1S c;  4C3J L;  3RYG A;  5MGN A;  5EIN C;  2JI2 A;  1ODH A;  5AI3 A;  4LHL A;  5MFZ A;  4A93 L;  4B8C D;  2KKD A;  1R9T L;  1I6H L;  4X6A L;  1QCV A;  3GTJ L;  2NVY L;  5M5W L;  2AUS B;  2XJU A;  3VPB E;  2E2J L;  1F4L A;  2B5I D;  3S1M L;  5JVG 1;  4AHZ A;  2AYJ A;  4UY8 1;  4BBR L;  2QL0 A;  3JR7 A;  3M3Y L;  5GAH c;  2JA5 L;  1BQ8 A;  2E2H L;  3S1R L;  4A3E L;  3H97 A;  2PYA A;  2XJV A;  1VZH A;  3M4O L;  1PFV A;  5C3E L;  4BY7 L;  2A69 D;  1I3Q L;  5M3F L;  5C4J L;  2J9U B;  3PKJ A;  4GS7 D;  1R0G A;  1IU5 A;  1NNQ A;  5M5X L;  4YWM A;  1OWB A;  2A6H D;  2HVY C;  3KYU A;  4BY1 L;  3QVD A;  3GTM L;  3RZD L;  2XJP A;  2V0E A;  2XJR A;  2JA7 L;  2JI3 A;  3GTK L;  2Z3R B;  4RXN A;  1PZX A;  1SMM A;  1IW7 D;  1RB9 A;  1CAA A;  3I4N L;  4JAE A;  4AR4 A;  1TWA L;  3LWQ B;  3KYV A;  1R0I A;  3GTQ L;  1T9Q A;  2Y0S P;  4TPU A;  4AR6 A;  1NXG A;  1P7P A;  3S2D L;  4QIW P;  1S24 A;  2ZIX A;  3RZ6 A;  6RXN A;  3FDJ A;  4A3M L;  4C3I L;  3MQK B;  1VZI A;  3NFP I;  1T9O A;  4ZN3 B;  2PPT A;  1SMU A;  3PWF A;  1LKO A;  4A3D L;  2NVX L;  4A3B L;  2WB1 P;  4AHX A;  2CR8 A;  3P2A A;  1K83 L;  3HOV L;  2Z3Q B;  1DX8 A;  2C6A A;  2RDV A;  7RXN A;  2M4V A;  3GTG L;  2YU9 L;  3S16 L;  1R0H A;  1Z92 B;  3HKZ P;  3HOZ L;  4G6B A;  3PKI A;  2R93 L;  5JVH 1;  4V19 6;  3WWL A;  2JA6 L;  4C2M 1;  3B08 B;  4AI1 A;  3GTL L;  2LCQ A;  2KN9 A;  2BE5 D;  3KYX A;  2NYD A;  8RXN A;  1RWD A;  2M6P A;  4A3K L;  5GAD c;  5MLC 3;  4AHY A;  1NXE A;  2NVT L;  1BQ9 A;  3PIP 1;  3H99 A;  1TWG L;  5GAE c;  1WCM L;  4WFN 1;  3WWN B;  3H0G L;  2H12 A;  2CKA A;  4YWL A;  1RYQ A;  2JI1 A;  1YK5 A;  1B2J A;  3S17 L;  2MS3 A;  4A3I L;  4K9F A;  2VUM L;  1LTL A;  1B71 A;  1TWH L;  1TWC L;  1LKM A;  3ZG6 A;  3HJW B;  4A3F L;  1OWC A;  1B13 A;  1RDG A;  2WAQ P;  2JA8 L;  3A44 A;  2DSX A;  3HOX L;  3HOU L;  3MPS A;  1E8J A;  2APO B;  3HOY L;  3GTO L;  2AQC A;  4JAG A;  2R92 L;  2C6B A;  4BBS L;  4ME3 A;  3LWO B;  3S15 L;  2E2I L;  4C3H L;  3GTP L;  3RZO L;  3KYY A;  4AR5 A;  3LWR B;  3PO2 L;  4XXB B;  1C09 A;  5IYB L;  2GMG A;  1TWF L;  1BRF A;  2R7Z L;  1IU6 A;  3S1Q L;  3LNL A;  4AI0 A;  3J7Y 1;  1FHH A;  2CKC A;  1YUX A;  2K2D A;  5M3M L;  1YK4 A;  4POG A;  3PL5 A;  4E6Y A;  1RDV A;  3J7Z 1;  3FKI L;  3K35 A;  3LWP B;  2L0Z A;  3IU3 I;  1SFO L;  1R0J A;  5IY0 A;  1Y1W L;  5AN9 H;  5GAG c;  4JAD A;  1VZG A;  5FLM L;  2PMZ P;  2V0F A;  5MF6 A;  4LHN A;  1PFU A;  1QYB A;  4JAF A;  1I50 L;  4AR3 A;  1QQT A;  1S30 A;  1FHM A;  2V3B B;  4POF A;  3S14 L;  5IP9 L;  4Y52 L;  1YV1 A;  1ZRP A;  3B0A B;  3HAX C;  3KYW A;  5IYD L;  5EIO C;  3H9C A;  3H3V M;  1R0F A;  3HOW L;  4A3J L;  1DVB A;  1BFY A;  5FJ8 L;  2M6O A;  1YUZ A;  5DM6 1;  3PO3 L;  3RZT A;  5C44 L;  3PZA A;  4ZN1 B;  2O5J D;  1RYT A;  2A6E D;  2ERJ A;  4A3L L;  4Y7N L;  1VCX A;  2NVQ L;  1JYB A;  1T9P A;  2XJQ A;  3MSU A;  3S1N L;  2EY4 E;  2B63 L;  1BE7 A;  4AYB P;  3QQC E;  3H9B A;  1LKP A;  3HJY B;  3P8B A;  4AHW A;  1PFW A;  3S2H L;  3K7A L;  3I4M L;  2XJS A;  1CAD A;  2ERS A;  4TVM A;  4AI2 A;  1SMW A;  1B2O A;  2HR5 A;  1IRN A;  1Y1V L;  5M5Y L;  5MFP A; 
#chains in the Genus database with same CATH homology
 5IP7 L;  4BY1 L;  2NVT L;  5M3M L;  3GTM L;  3CQZ L;  3RZD L;  5C4X L;  1TWG L;  2JA7 L;  4BXX L;  3GTK L;  1WCM L;  4A3G L;  3FKI L;  3I4N L;  1TWA L;  3H0G L;  1SFO L;  3GTQ L;  2Y0S P;  1Y1W L;  4A3C L;  5FLM L;  3S2D L;  2PMZ P;  5IYC L;  4QIW P;  3S17 L;  4A3I L;  2VUM L;  1I50 L;  3S14 L;  5IP9 L;  4C3J L;  4C3I L;  4A3M L;  4Y52 L;  1TWH L;  1TWC L;  4A93 L;  5IYD L;  4A3F L;  1R9T L;  1I6H L;  2WAQ P;  2JA8 L;  3H3V M;  4X6A L;  3HOW L;  3GTJ L;  4A3J L;  4A3D L;  5FJ8 L;  2NVX L;  2NVY L;  5M5W L;  3HOX L;  3HOU L;  4A3B L;  2WB1 P;  3PO3 L;  1K83 L;  5C44 L;  2E2J L;  3HOV L;  3S1M L;  4A3L L;  4BBR L;  3HOY L;  3GTO L;  4Y7N L;  3GTG L;  2YU9 L;  2NVQ L;  3S16 L;  3M3Y L;  2JA5 L;  3HKZ P;  2R92 L;  2E2H L;  3S1N L;  3S1R L;  4A3E L;  2B63 L;  4BBS L;  3HOZ L;  2R93 L;  4AYB P;  3S15 L;  2E2I L;  3M4O L;  5C3E L;  4BY7 L;  2JA6 L;  4C2M 1;  4C3H L;  1I3Q L;  3GTP L;  5M3F L;  5C4J L;  3RZO L;  3S2H L;  3K7A L;  3I4M L;  3GTL L;  3PO2 L;  5IYB L;  5M5X L;  1TWF L;  4A3K L;  2R7Z L;  1Y1V L;  5M5Y L;  3S1Q L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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