2EY4E

Crystal structure of a cbf5-nop10-gar1 complex
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
52
structure length
52
Chain Sequence
RIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLGI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a Cbf5-Nop10-Gar1 complex and implications in RNA-guided pseudouridylation and dyskeratosis congenita.
pubmed doi rcsb
molecule tags Isomerase/biosynthetic protein
source organism Pyrococcus furiosus
molecule keywords Probable tRNA pseudouridine synthase B
total genus 8
structure length 52
sequence length 52
chains with identical sequence F
ec nomenclature
pdb deposition date 2005-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF04135 Nop10p Nucleolar RNA-binding protein, Nop10p family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.40 Mainly Beta Single Sheet Rubrerythrin, domain 2 H/ACA ribonucleoprotein complex, subunit Nop10 2ey4E00
2APOB 2EY4E 2HVYC 2RFKB 3LWOB 2AUSB 3MQKB 3HJYB 3LWVB 3HAXC 3LWPB 2AQCA 3LWRB 3HJWB 3LWQB
chains in the Genus database with same CATH superfamily
1YV1A 3LNLA 3MQKB 3J7Y1 3KYXA 2VL6A 7RXNA 1DVBA 3S2DL 2CKCA 1WCML 4U671 4UY81 1FHHA 2YU9L 2CKAA 1PFUA 5GADc 4AHYA 1LTLA 2APOB 1BFYA 2WB1P 2R92L 3GTPL 3HOYL 4Y52L 2PPTA 2ZIXA 4Y7NL 1SMWA 2PYAA 4TVMA 4AR4A 1PFYA 3WWLA 5MFZA 3HOUL 4YWMA 4JAGA 2JA7L 3S15L 4AI1A 4AHWA 2EY4E 3HOWL 3HKZP 2L0ZA 2RFKB 4AHXA 4BY7L 3B0AB 4AI3A 5MGNA 3IU3I 1OWBA 5IY0A 1PZXA 2WAQP 2QL0A 2A6HD 1YUXA 3RZTA 2CR8A 3RZDL 1R0GA 2PVXA 2XJVA 3PKIA 1JYBA 2NVXL 1VCXA 3LPEB 1Y1WL 2JA8L 2PVEA 2MS3A 3GTML 3P2AA 4JADA 3S17L 3H97A 2XJTA 4GS7D 2A69D 1CADA 1TWFL 4WFN1 3I4NL 3PIP1 3GTKL 2M6OA 4A3GL 5M5WL 4XGHA 1RWDA 1RYTA 3A44A 2E2IL 5MFPA 3HJWB 3S1RL 4AI2A 1R0JA 3B08B 1RYQA 4ME3A 4BY1L 3S1NL 1QQTA 2C6BA 1RDGA 3MPSA 4AR5A 5AI3A 3LWVB 3PIO1 4C3HL 5JVH1 5DM71 2JI2A 5M3FL 2V0FA 3QVDA 1LKMA 4LHLA 1NXEA 1BE7A 5EINC 5DM61 3PZAA 5GAGc 5EIOC 2Z3QB 3GTQL 3LWQB 1CAAA 3M4OL 2ERJA 1T9PA 4C2M1 5C4JL 5M5YL 4A3CL 3S1QL 1IRNA 5K2ME 2JA5L 5GAHc 1RB9A 2J9UB 1DX8A 2DSXA 2XJSA 2HVYC 1C09A 4AHZA 2JI1A 4POGA 4AI0A 2O5JD 3K35A 1R0FA 3H99A 1ODHA 4JAEA 5M5XL 3FDJA 3CQZL 3KYUA 5C4XL 3GTGL 2LCQA 3S1ML 2Z3RB 5IP7L 4C3JL 3KYVA 3FKIL 3LWOB 3PWFA 2H12A 1SMUA 2PSMC 1WJVA 1QCVA 3RYGA 1NNQA 3PO3L 1T9QA 4A3FL 1H7VA 2B5ID 1VZHA 1B71A 3PKJA 8RXNA 1TWGL 3S14L 2AUSB 1TWHL 2VUML 3GTJL 1OWCA 4A3IL 2RDVA 3JR7A 1IU6A 3GTLL 2B63L 2R7ZL 2R93L 3NFPI 4A3ML 5IYCL 3MSUA 3LWRB 2KN9A 3PL5A 1B2OA 5C44L 3ZG6A 5AI2A 5RXNA 2NVTL 1BRFA 2Y0SP 1I6HL 2M4YA 4POFA 1E8JA 4A3BL 6RXNA 1R9TL 3H0GL 2KKDA 2V0EA 1IROA 3HOZL 4A3DL 5JVG1 2ERSA 5M3ML 2E2JL 1SFOL 2AQCA 1BQ8A 3RZOL 3P8BA 3S2HL 2XJPA 1K83L 1YK4A 2XJRA 2GMGA 4BBRL 3VPBE 4B8CD 4LHNA 2C6AA 1Y1VL 4A3EL 4ZN1B 4X6AL 1F4LA 4V196 2A68D 1IW7D 3RZ6A 3QQCE 1I50L 1I3QL 3HOVL 4A3JL 4RXNA 1P7PA 3SS2A 4YWLA 5IP9L 2JI3A 4A3KL 1R0HA 4K9FA 3KYYA 3PO2L 2M4VA 2AYJA 5MF6A 2XJUA 1Z92B 1S2ZA 1S24A 3HJYB 3KYWA 4E6YA 2A6ED 5MLC3 5FJ8L 1T9OA 2HR5A 2M6PA 2K2DA 4BXXL 3S16L 4AR6A 3J7Z1 3M3YL 2E2HL 4G6BA 4ZN3B 1SMMA 2NVQL 3K7AL 1YUZA 3HOXL 1BQ9A 1LKPA 2NYDA 1S30A 4JAFA 4A3LL 3I4ML 1IU5A 1TWAL 1NXGA 1YK5A 5GAEc 1PFWA 4BBSL 1QYBA 2NVYL 4QIWP 5AN9H 3H3VM 2BE5D 5FLML 3LWPB 1VZIA 3H9CA 1B2JA 4AYBP 1R0IA 2V3BB 2XJQA 5IYBL 4C3IL 1B13A 3HAXC 4A93L 1RDVA 1VZGA 4TPUA 1TWCL 5H1Sc 1PFVA 5IYDL 1ZRPA 3WWNB 5C3EL 3GTOL 2JA6L 1FHMA 3H9BA 2PMZP 4XXBB 1LKOA 4AR3A
chains in the Genus database with same CATH topology
2APOB 2EY4E 2HVYC 2RFKB 3LWOB 2AUSB 3MQKB 3HJYB 3LWVB 3HAXC 3LWPB 2AQCA 3LWRB 3HJWB 3LWQB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2APO B;  2EY4 E;  2HVY C;  2RFK B;  3LWO B;  2AUS B;  3MQK B;  3HJY B;  3LWV B;  3HAX C;  3LWP B;  2AQC A;  3LWR B;  3HJW B;  3LWQ B; 
#chains in the Genus database with same CATH topology
 1YV1 A;  3LNL A;  3MQK B;  3J7Y 1;  3KYX A;  2VL6 A;  7RXN A;  1DVB A;  3S2D L;  2CKC A;  1WCM L;  4U67 1;  4UY8 1;  1FHH A;  2YU9 L;  2CKA A;  1PFU A;  5GAD c;  4AHY A;  1LTL A;  2APO B;  1BFY A;  2WB1 P;  2R92 L;  3GTP L;  3HOY L;  4Y52 L;  2PPT A;  2ZIX A;  4Y7N L;  1SMW A;  2PYA A;  4TVM A;  4AR4 A;  1PFY A;  3WWL A;  5MFZ A;  3HOU L;  4YWM A;  4JAG A;  2JA7 L;  3S15 L;  4AI1 A;  4AHW A;  2EY4 E;  3HOW L;  3HKZ P;  2L0Z A;  2RFK B;  4AHX A;  4BY7 L;  3B0A B;  4AI3 A;  5MGN A;  3IU3 I;  1OWB A;  5IY0 A;  1PZX A;  2WAQ P;  2QL0 A;  2A6H D;  1YUX A;  3RZT A;  2CR8 A;  3RZD L;  1R0G A;  2PVX A;  2XJV A;  3PKI A;  1JYB A;  2NVX L;  1VCX A;  3LPE B;  1Y1W L;  2JA8 L;  2PVE A;  2MS3 A;  3GTM L;  3P2A A;  4JAD A;  3S17 L;  3H97 A;  2XJT A;  4GS7 D;  2A69 D;  1CAD A;  1TWF L;  4WFN 1;  3I4N L;  3PIP 1;  3GTK L;  2M6O A;  4A3G L;  5M5W L;  4XGH A;  1RWD A;  1RYT A;  3A44 A;  2E2I L;  5MFP A;  3HJW B;  3S1R L;  4AI2 A;  1R0J A;  3B08 B;  1RYQ A;  4ME3 A;  4BY1 L;  3S1N L;  1QQT A;  2C6B A;  1RDG A;  3MPS A;  4AR5 A;  5AI3 A;  3LWV B;  3PIO 1;  4C3H L;  5JVH 1;  5DM7 1;  2JI2 A;  5M3F L;  2V0F A;  3QVD A;  1LKM A;  4LHL A;  1NXE A;  1BE7 A;  5EIN C;  5DM6 1;  3PZA A;  5GAG c;  5EIO C;  2Z3Q B;  3GTQ L;  3LWQ B;  1CAA A;  3M4O L;  2ERJ A;  1T9P A;  4C2M 1;  5C4J L;  5M5Y L;  4A3C L;  3S1Q L;  1IRN A;  5K2M E;  2JA5 L;  5GAH c;  1RB9 A;  2J9U B;  1DX8 A;  2DSX A;  2XJS A;  2HVY C;  1C09 A;  4AHZ A;  2JI1 A;  4POG A;  4AI0 A;  2O5J D;  3K35 A;  1R0F A;  3H99 A;  1ODH A;  4JAE A;  5M5X L;  3FDJ A;  3CQZ L;  3KYU A;  5C4X L;  3GTG L;  2LCQ A;  3S1M L;  2Z3R B;  5IP7 L;  4C3J L;  3KYV A;  3FKI L;  3LWO B;  3PWF A;  2H12 A;  1SMU A;  2PSM C;  1WJV A;  1QCV A;  3RYG A;  1NNQ A;  3PO3 L;  1T9Q A;  4A3F L;  1H7V A;  2B5I D;  1VZH A;  1B71 A;  3PKJ A;  8RXN A;  1TWG L;  3S14 L;  2AUS B;  1TWH L;  2VUM L;  3GTJ L;  1OWC A;  4A3I L;  2RDV A;  3JR7 A;  1IU6 A;  3GTL L;  2B63 L;  2R7Z L;  2R93 L;  3NFP I;  4A3M L;  5IYC L;  3MSU A;  3LWR B;  2KN9 A;  3PL5 A;  1B2O A;  5C44 L;  3ZG6 A;  5AI2 A;  5RXN A;  2NVT L;  1BRF A;  2Y0S P;  1I6H L;  2M4Y A;  4POF A;  1E8J A;  4A3B L;  6RXN A;  1R9T L;  3H0G L;  2KKD A;  2V0E A;  1IRO A;  3HOZ L;  4A3D L;  5JVG 1;  2ERS A;  5M3M L;  2E2J L;  1SFO L;  2AQC A;  1BQ8 A;  3RZO L;  3P8B A;  3S2H L;  2XJP A;  1K83 L;  1YK4 A;  2XJR A;  2GMG A;  4BBR L;  3VPB E;  4B8C D;  4LHN A;  2C6A A;  1Y1V L;  4A3E L;  4ZN1 B;  4X6A L;  1F4L A;  4V19 6;  2A68 D;  1IW7 D;  3RZ6 A;  3QQC E;  1I50 L;  1I3Q L;  3HOV L;  4A3J L;  4RXN A;  1P7P A;  3SS2 A;  4YWL A;  5IP9 L;  2JI3 A;  4A3K L;  1R0H A;  4K9F A;  3KYY A;  3PO2 L;  2M4V A;  2AYJ A;  5MF6 A;  2XJU A;  1Z92 B;  1S2Z A;  1S24 A;  3HJY B;  3KYW A;  4E6Y A;  2A6E D;  5MLC 3;  5FJ8 L;  1T9O A;  2HR5 A;  2M6P A;  2K2D A;  4BXX L;  3S16 L;  4AR6 A;  3J7Z 1;  3M3Y L;  2E2H L;  4G6B A;  4ZN3 B;  1SMM A;  2NVQ L;  3K7A L;  1YUZ A;  3HOX L;  1BQ9 A;  1LKP A;  2NYD A;  1S30 A;  4JAF A;  4A3L L;  3I4M L;  1IU5 A;  1TWA L;  1NXG A;  1YK5 A;  5GAE c;  1PFW A;  4BBS L;  1QYB A;  2NVY L;  4QIW P;  5AN9 H;  3H3V M;  2BE5 D;  5FLM L;  3LWP B;  1VZI A;  3H9C A;  1B2J A;  4AYB P;  1R0I A;  2V3B B;  2XJQ A;  5IYB L;  4C3I L;  1B13 A;  3HAX C;  4A93 L;  1RDV A;  1VZG A;  4TPU A;  1TWC L;  5H1S c;  1PFV A;  5IYD L;  1ZRP A;  3WWN B;  5C3E L;  3GTO L;  2JA6 L;  1FHM A;  3H9B A;  2PMZ P;  4XXB B;  1LKO A;  4AR3 A; 
#chains in the Genus database with same CATH homology
 2APO B;  2EY4 E;  2HVY C;  2RFK B;  3LWO B;  2AUS B;  3MQK B;  3HJY B;  3LWV B;  3HAX C;  3LWP B;  2AQC A;  3LWR B;  3HJW B;  3LWQ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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