2K2DA

Solution nmr structure of c-terminal domain of human pirh2. northeast structural genomics consortium (nesg) target ht2c
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
47
structure length
47
Chain Sequence
NMTVDILCNDCNGRSTVQFHILGMKCKICESYNTAQAGGRRISLDQQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of Pirh2-mediated p53 ubiquitylation.
pubmed doi rcsb
molecule tags Metal binding protein
source organism Homo sapiens
molecule keywords RING finger and CHY zinc finger domain-containing protein 1
total genus 7
structure length 47
sequence length 47
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-03-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14599 zinc_ribbon_6 Zinc-ribbon
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.10 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2k2dA00
3KYWA 2MS3A 1B2OA 1YUZA 1LKOA 1DX8A 1T9PA 1YUXA 7RXNA 3SS2A 4AR3A 2M4YA 1T9QA 1IROA 1FHMA 3A44A 4RXNA 1LKMA 2KN9A 2K2DA 1IU6A 1NNQA 4TPUA 2PVEA 1R0GA 5AI3A 1BRFA 1CAAA 2HR5A 1R0IA 2PYAA 1RDVA 2PVXA 1BQ8A 1DVBA 1RDGA 4ME3A 1BQ9A 8RXNA 2GMGA 1C09A 1SMMA 3PWFA 2LCQA 2QL0A 1BFYA 3KYYA 2VL6A 1YK4A 1QYBA 6RXNA 4AR5A 3RZTA 1E8JA 1QCVA 1B13A 1RYTA 1YK5A 3QVDA 3RZ6A 1BE7A 2KKDA 1CADA 1S30A 4YWLA 1SMWA 1RB9A 1VCXA 1R0JA 3RYGA 3MPSA 4AR6A 1YV1A 1RWDA 1IU5A 4POGA 1S2ZA 5RXNA 1IRNA 3PZAA 1H7VA 2RDVA 1R0FA 4YWMA 1B2JA 3KYUA 4AR4A 4POFA 2V3BB 3KYVA 1LKPA 1FHHA 1SMUA 1S24A 1T9OA 3KYXA 5IY0A 1B71A 2DSXA 1JYBA 1ZRPA 5AI2A 1R0HA 4K9FA 1LTLA
chains in the Genus database with same CATH superfamily
4A3FL 3M3YL 1RYQA 1B2OA 3S17L 5MFZA 3S2HL 4A3BL 1YUXA 3HJWB 1R9TL 5FLML 4LHLA 4ZN3B 4AR3A 1IROA 1FHMA 4C3IL 4RXNA 1LKMA 2KN9A 1TWAL 4A3KL 4BBSL 4TPUA 2ZIXA 2CR8A 1R0GA 4Y52L 5AI3A 4A3LL 2XJPA 3GTML 2NVYL 2PYAA 1RDVA 1BQ8A 1TWCL 3S2DL 1BQ9A 3P8BA 3LWPB 5MFPA 1C09A 1SMMA 1BFYA 3KYYA 4A3GL 4X6AL 3HOZL 3S1QL 5MGNA 6RXNA 1E8JA 4AYBP 4C2M1 4C3JL 1VZGA 3RZ6A 2NYDA 5C4JL 2AQCA 3PIO1 3S1ML 4LHNA 1RB9A 3H0GL 2XJTA 4BY1L 3MPSA 2O5JD 3M4OL 1RWDA 2VUML 1IU5A 3GTJL 2RDVA 4C3HL 1B2JA 2BE5D 4POFA 2V3BB 3PKIA 2JA5L 2M4VA 3FDJA 3HKZP 2JI3A 3KYXA 1JYBA 4B8CD 5JVH1 4XGHA 1R0HA 4XXBB 1OWBA 2WAQP 5C3EL 2C6AA 2XJUA 4BBRL 3K35A 5IYCL 3S16L 1DX8A 1T9PA 2R7ZL 1I3QL 4WFN1 1T9QA 1Z92B 2A69D 1IU6A 4A3IL 4AI2A 4JAGA 5FJ8L 2RFKB 4ZN1B 3B08B 4JAEA 2V0EA 5H1Sc 1DVBA 2H12A 5M5WL 3P2AA 2VL6A 5GAHc 3PKJA 2WB1P 3I4NL 5M3FL 3IU3I 4AR5A 5K2ME 1RYTA 2PPTA 5IP9L 3QVDA 3LWVB 1BE7A 4U671 4AHZA 2EY4E 1Y1VL 2M6PA 1P7PA 5EIOC 5GAGc 4A3DL 2JI2A 2Y0SP 3LWQB 5DM61 5AN9H 3VPBE 1IRNA 2AYJA 2XJQA 4AI1A 3RZOL 1H7VA 2CKAA 3J7Z1 4TVMA 2M6OA 1NXGA 3RZDL 3KYUA 4AR4A 3S1NL 3KYVA 2JA6L 1FHHA 1OWCA 3HJYB 1S24A 3GTKL 2APOB 5IYDL 2DSXA 3LWRB 2JI1A 4JAFA 1ZRPA 1TWGL 2NVTL 2A68D 1VZIA 3I4ML 3GTLL 3HOUL 4K9FA 3PL5A 3MQKB 2MS3A 4AI3A 2Z3RB 7RXNA 3SS2A 5C4XL 5DM71 3S1RL 3A44A 1TWFL 1NNQA 3H97A 1PFWA 3WWNB 3LNLA 2B63L 2R92L 1BRFA 2JA8L 1CAAA 1R0IA 2E2HL 4AHWA 2PVXA 1WCML 1RDGA 4ME3A 8RXNA 1SFOL 3LPEB 3GTQL 3H9BA 5M5XL 4GS7D 3B0AB 5MLC3 2NVQL 4AHYA 5M3ML 3RZTA 1QCVA 2XJRA 2KKDA 3PO2L 1K83L 4YWLA 5GADc 3J7Y1 4A3JL 1SMWA 5MF6A 1ODHA 4A3EL 1R0JA 3RYGA 3S14L 3LWOB 1YV1A 4QIWP 4POGA 1F4LA 1S2ZA 1PFYA 2A6HD 2XJVA 1R0FA 2ERJA 5IP7L 5IYBL 2E2IL 1VZHA 3CQZL 4A3ML 1NXEA 2A6ED 5C44L 1SMUA 4A3CL 4G6BA 5EINC 5IY0A 3K7AL 5AI2A 3HAXC 1I6HL 3H9CA 2L0ZA 3NFPI 3KYWA 5JVG1 3H3VM 1YUZA 2R93L 1LKOA 4E6YA 1LTLA 2V0FA 3WWLA 2YU9L 2M4YA 3HOYL 5GAEc 2K2DA 2PVEA 2HVYC 3FKIL 2Z3QB 2HR5A 3PO3L 3HOXL 4UY81 3S15L 3HOVL 1IW7D 1WJVA 4BY7L 3MSUA 2GMGA 3PWFA 2LCQA 2QL0A 4AI0A 1YK4A 2B5ID 1QYBA 1I50L 1B13A 2J9UB 4AHXA 4A93L 1YK5A 3GTGL 5M5YL 2E2JL 3ZG6A 1CADA 1S30A 2JA7L 1TWHL 3QQCE 1VCXA 4V196 2NVXL 3PIP1 4AR6A 2PMZP 3HOWL 5RXNA 2CKCA 2XJSA 2ERSA 4JADA 3PZAA 1Y1WL 3GTPL 4Y7NL 3JR7A 1PFUA 4YWMA 3GTOL 1LKPA 4BXXL 1PZXA 1T9OA 1B71A 2PSMC 2C6BA 2AUSB 1PFVA 1QQTA 3H99A
chains in the Genus database with same CATH topology
2L0ZA 3NFPI 3KYWA 5JVG1 2C6AA 2XJUA 2MS3A 1RYQA 3K35A 1B2OA 1YUZA 4AI3A 5MFZA 1LKOA 4E6YA 2Z3RB 1DX8A 1T9PA 2V0FA 3WWLA 1YUXA 7RXNA 3SS2A 4LHLA 4ZN3B 4AR3A 2M4YA 4WFN1 5DM71 1T9QA 1Z92B 1IROA 1FHMA 3A44A 4RXNA 5GAEc 1LKMA 2A69D 2KN9A 2K2DA 1IU6A 1NNQA 4AI2A 4TPUA 2ZIXA 2PVEA 2CR8A 1R0GA 3WWNB 3LNLA 4JAGA 2Z3QB 5AI3A 1BRFA 1CAAA 2HR5A 4ZN1B 1R0IA 3B08B 2XJPA 4JAEA 4UY81 4AHWA 2PYAA 1RDVA 2PVXA 2V0EA 5H1Sc 1BQ8A 1IW7D 1DVBA 1WJVA 1RDGA 2H12A 4ME3A 3MSUA 1BQ9A 8RXNA 3LPEB 3P8BA 2GMGA 5MFPA 1C09A 1SMMA 3PWFA 4GS7D 2LCQA 2QL0A 3P2AA 3KYYA 3B0AB 2VL6A 4AI0A 5GAHc 1YK4A 1BFYA 2B5ID 5MLC3 3PKJA 1QYBA 5MGNA 6RXNA 3IU3I 4AHYA 4AR5A 3RZTA 1E8JA 1QCVA 5K2ME 1B13A 2J9UB 1RYTA 2XJRA 4AHXA 2PPTA 1YK5A 3QVDA 1VZGA 3RZ6A 1BE7A 2NYDA 4U671 2KKDA 3ZG6A 4AHZA 1CADA 1S30A 3PIO1 2M6PA 4YWLA 5GADc 5EIOC 5GAGc 1SMWA 3J7Y1 3QQCE 4LHNA 1RB9A 1VCXA 5MF6A 2JI2A 4V196 1ODHA 2XJTA 1R0JA 3RYGA 3MPSA 2O5JD 5DM61 3PIP1 4AR6A 1YV1A 1RWDA 5AN9H 1IU5A 4POGA 1S2ZA 5RXNA 2CKCA 2XJSA 3VPBE 2AYJA 2ERSA 1IRNA 2A6HD 2XJQA 3PZAA 4JADA 2CKAA 2RDVA 4AI1A 2XJVA 3J7Z1 1H7VA 1R0FA 4TVMA 2ERJA 4YWMA 1B2JA 2BE5D 2M6OA 1NXGA 3KYUA 4AR4A 1VZHA 4POFA 1NXEA 2V3BB 2A6ED 3KYVA 3PKIA 1LKPA 1FHHA 1OWCA 2M4VA 1SMUA 1S24A 4G6BA 5EINC 1T9OA 2JI3A 3KYXA 5IY0A 1B71A 2DSXA 2JI1A 1JYBA 4JAFA 4B8CD 2PSMC 1ZRPA 5JVH1 2C6BA 4XGHA 5AI2A 1R0HA 4XXBB 2A68D 1OWBA 1VZIA 4K9FA 1LTLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KYW A;  2MS3 A;  1B2O A;  1YUZ A;  1LKO A;  1DX8 A;  1T9P A;  1YUX A;  7RXN A;  3SS2 A;  4AR3 A;  2M4Y A;  1T9Q A;  1IRO A;  1FHM A;  3A44 A;  4RXN A;  1LKM A;  2KN9 A;  2K2D A;  1IU6 A;  1NNQ A;  4TPU A;  2PVE A;  1R0G A;  5AI3 A;  1BRF A;  1CAA A;  2HR5 A;  1R0I A;  2PYA A;  1RDV A;  2PVX A;  1BQ8 A;  1DVB A;  1RDG A;  4ME3 A;  1BQ9 A;  8RXN A;  2GMG A;  1C09 A;  1SMM A;  3PWF A;  2LCQ A;  2QL0 A;  1BFY A;  3KYY A;  2VL6 A;  1YK4 A;  1QYB A;  6RXN A;  4AR5 A;  3RZT A;  1E8J A;  1QCV A;  1B13 A;  1RYT A;  1YK5 A;  3QVD A;  3RZ6 A;  1BE7 A;  2KKD A;  1CAD A;  1S30 A;  4YWL A;  1SMW A;  1RB9 A;  1VCX A;  1R0J A;  3RYG A;  3MPS A;  4AR6 A;  1YV1 A;  1RWD A;  1IU5 A;  4POG A;  1S2Z A;  5RXN A;  1IRN A;  3PZA A;  1H7V A;  2RDV A;  1R0F A;  4YWM A;  1B2J A;  3KYU A;  4AR4 A;  4POF A;  2V3B B;  3KYV A;  1LKP A;  1FHH A;  1SMU A;  1S24 A;  1T9O A;  3KYX A;  5IY0 A;  1B71 A;  2DSX A;  1JYB A;  1ZRP A;  5AI2 A;  1R0H A;  4K9F A;  1LTL A; 
#chains in the Genus database with same CATH topology
 4A3F L;  3M3Y L;  1RYQ A;  1B2O A;  3S17 L;  5MFZ A;  3S2H L;  4A3B L;  1YUX A;  3HJW B;  1R9T L;  5FLM L;  4LHL A;  4ZN3 B;  4AR3 A;  1IRO A;  1FHM A;  4C3I L;  4RXN A;  1LKM A;  2KN9 A;  1TWA L;  4A3K L;  4BBS L;  4TPU A;  2ZIX A;  2CR8 A;  1R0G A;  4Y52 L;  5AI3 A;  4A3L L;  2XJP A;  3GTM L;  2NVY L;  2PYA A;  1RDV A;  1BQ8 A;  1TWC L;  3S2D L;  1BQ9 A;  3P8B A;  3LWP B;  5MFP A;  1C09 A;  1SMM A;  1BFY A;  3KYY A;  4A3G L;  4X6A L;  3HOZ L;  3S1Q L;  5MGN A;  6RXN A;  1E8J A;  4AYB P;  4C2M 1;  4C3J L;  1VZG A;  3RZ6 A;  2NYD A;  5C4J L;  2AQC A;  3PIO 1;  3S1M L;  4LHN A;  1RB9 A;  3H0G L;  2XJT A;  4BY1 L;  3MPS A;  2O5J D;  3M4O L;  1RWD A;  2VUM L;  1IU5 A;  3GTJ L;  2RDV A;  4C3H L;  1B2J A;  2BE5 D;  4POF A;  2V3B B;  3PKI A;  2JA5 L;  2M4V A;  3FDJ A;  3HKZ P;  2JI3 A;  3KYX A;  1JYB A;  4B8C D;  5JVH 1;  4XGH A;  1R0H A;  4XXB B;  1OWB A;  2WAQ P;  5C3E L;  2C6A A;  2XJU A;  4BBR L;  3K35 A;  5IYC L;  3S16 L;  1DX8 A;  1T9P A;  2R7Z L;  1I3Q L;  4WFN 1;  1T9Q A;  1Z92 B;  2A69 D;  1IU6 A;  4A3I L;  4AI2 A;  4JAG A;  5FJ8 L;  2RFK B;  4ZN1 B;  3B08 B;  4JAE A;  2V0E A;  5H1S c;  1DVB A;  2H12 A;  5M5W L;  3P2A A;  2VL6 A;  5GAH c;  3PKJ A;  2WB1 P;  3I4N L;  5M3F L;  3IU3 I;  4AR5 A;  5K2M E;  1RYT A;  2PPT A;  5IP9 L;  3QVD A;  3LWV B;  1BE7 A;  4U67 1;  4AHZ A;  2EY4 E;  1Y1V L;  2M6P A;  1P7P A;  5EIO C;  5GAG c;  4A3D L;  2JI2 A;  2Y0S P;  3LWQ B;  5DM6 1;  5AN9 H;  3VPB E;  1IRN A;  2AYJ A;  2XJQ A;  4AI1 A;  3RZO L;  1H7V A;  2CKA A;  3J7Z 1;  4TVM A;  2M6O A;  1NXG A;  3RZD L;  3KYU A;  4AR4 A;  3S1N L;  3KYV A;  2JA6 L;  1FHH A;  1OWC A;  3HJY B;  1S24 A;  3GTK L;  2APO B;  5IYD L;  2DSX A;  3LWR B;  2JI1 A;  4JAF A;  1ZRP A;  1TWG L;  2NVT L;  2A68 D;  1VZI A;  3I4M L;  3GTL L;  3HOU L;  4K9F A;  3PL5 A;  3MQK B;  2MS3 A;  4AI3 A;  2Z3R B;  7RXN A;  3SS2 A;  5C4X L;  5DM7 1;  3S1R L;  3A44 A;  1TWF L;  1NNQ A;  3H97 A;  1PFW A;  3WWN B;  3LNL A;  2B63 L;  2R92 L;  1BRF A;  2JA8 L;  1CAA A;  1R0I A;  2E2H L;  4AHW A;  2PVX A;  1WCM L;  1RDG A;  4ME3 A;  8RXN A;  1SFO L;  3LPE B;  3GTQ L;  3H9B A;  5M5X L;  4GS7 D;  3B0A B;  5MLC 3;  2NVQ L;  4AHY A;  5M3M L;  3RZT A;  1QCV A;  2XJR A;  2KKD A;  3PO2 L;  1K83 L;  4YWL A;  5GAD c;  3J7Y 1;  4A3J L;  1SMW A;  5MF6 A;  1ODH A;  4A3E L;  1R0J A;  3RYG A;  3S14 L;  3LWO B;  1YV1 A;  4QIW P;  4POG A;  1F4L A;  1S2Z A;  1PFY A;  2A6H D;  2XJV A;  1R0F A;  2ERJ A;  5IP7 L;  5IYB L;  2E2I L;  1VZH A;  3CQZ L;  4A3M L;  1NXE A;  2A6E D;  5C44 L;  1SMU A;  4A3C L;  4G6B A;  5EIN C;  5IY0 A;  3K7A L;  5AI2 A;  3HAX C;  1I6H L;  3H9C A;  2L0Z A;  3NFP I;  3KYW A;  5JVG 1;  3H3V M;  1YUZ A;  2R93 L;  1LKO A;  4E6Y A;  1LTL A;  2V0F A;  3WWL A;  2YU9 L;  2M4Y A;  3HOY L;  5GAE c;  2K2D A;  2PVE A;  2HVY C;  3FKI L;  2Z3Q B;  2HR5 A;  3PO3 L;  3HOX L;  4UY8 1;  3S15 L;  3HOV L;  1IW7 D;  1WJV A;  4BY7 L;  3MSU A;  2GMG A;  3PWF A;  2LCQ A;  2QL0 A;  4AI0 A;  1YK4 A;  2B5I D;  1QYB A;  1I50 L;  1B13 A;  2J9U B;  4AHX A;  4A93 L;  1YK5 A;  3GTG L;  5M5Y L;  2E2J L;  3ZG6 A;  1CAD A;  1S30 A;  2JA7 L;  1TWH L;  3QQC E;  1VCX A;  4V19 6;  2NVX L;  3PIP 1;  4AR6 A;  2PMZ P;  3HOW L;  5RXN A;  2CKC A;  2XJS A;  2ERS A;  4JAD A;  3PZA A;  1Y1W L;  3GTP L;  4Y7N L;  3JR7 A;  1PFU A;  4YWM A;  3GTO L;  1LKP A;  4BXX L;  1PZX A;  1T9O A;  1B71 A;  2PSM C;  2C6B A;  2AUS B;  1PFV A;  1QQT A;  3H99 A; 
#chains in the Genus database with same CATH homology
 2L0Z A;  3NFP I;  3KYW A;  5JVG 1;  2C6A A;  2XJU A;  2MS3 A;  1RYQ A;  3K35 A;  1B2O A;  1YUZ A;  4AI3 A;  5MFZ A;  1LKO A;  4E6Y A;  2Z3R B;  1DX8 A;  1T9P A;  2V0F A;  3WWL A;  1YUX A;  7RXN A;  3SS2 A;  4LHL A;  4ZN3 B;  4AR3 A;  2M4Y A;  4WFN 1;  5DM7 1;  1T9Q A;  1Z92 B;  1IRO A;  1FHM A;  3A44 A;  4RXN A;  5GAE c;  1LKM A;  2A69 D;  2KN9 A;  2K2D A;  1IU6 A;  1NNQ A;  4AI2 A;  4TPU A;  2ZIX A;  2PVE A;  2CR8 A;  1R0G A;  3WWN B;  3LNL A;  4JAG A;  2Z3Q B;  5AI3 A;  1BRF A;  1CAA A;  2HR5 A;  4ZN1 B;  1R0I A;  3B08 B;  2XJP A;  4JAE A;  4UY8 1;  4AHW A;  2PYA A;  1RDV A;  2PVX A;  2V0E A;  5H1S c;  1BQ8 A;  1IW7 D;  1DVB A;  1WJV A;  1RDG A;  2H12 A;  4ME3 A;  3MSU A;  1BQ9 A;  8RXN A;  3LPE B;  3P8B A;  2GMG A;  5MFP A;  1C09 A;  1SMM A;  3PWF A;  4GS7 D;  2LCQ A;  2QL0 A;  3P2A A;  3KYY A;  3B0A B;  2VL6 A;  4AI0 A;  5GAH c;  1YK4 A;  1BFY A;  2B5I D;  5MLC 3;  3PKJ A;  1QYB A;  5MGN A;  6RXN A;  3IU3 I;  4AHY A;  4AR5 A;  3RZT A;  1E8J A;  1QCV A;  5K2M E;  1B13 A;  2J9U B;  1RYT A;  2XJR A;  4AHX A;  2PPT A;  1YK5 A;  3QVD A;  1VZG A;  3RZ6 A;  1BE7 A;  2NYD A;  4U67 1;  2KKD A;  3ZG6 A;  4AHZ A;  1CAD A;  1S30 A;  3PIO 1;  2M6P A;  4YWL A;  5GAD c;  5EIO C;  5GAG c;  1SMW A;  3J7Y 1;  3QQC E;  4LHN A;  1RB9 A;  1VCX A;  5MF6 A;  2JI2 A;  4V19 6;  1ODH A;  2XJT A;  1R0J A;  3RYG A;  3MPS A;  2O5J D;  5DM6 1;  3PIP 1;  4AR6 A;  1YV1 A;  1RWD A;  5AN9 H;  1IU5 A;  4POG A;  1S2Z A;  5RXN A;  2CKC A;  2XJS A;  3VPB E;  2AYJ A;  2ERS A;  1IRN A;  2A6H D;  2XJQ A;  3PZA A;  4JAD A;  2CKA A;  2RDV A;  4AI1 A;  2XJV A;  3J7Z 1;  1H7V A;  1R0F A;  4TVM A;  2ERJ A;  4YWM A;  1B2J A;  2BE5 D;  2M6O A;  1NXG A;  3KYU A;  4AR4 A;  1VZH A;  4POF A;  1NXE A;  2V3B B;  2A6E D;  3KYV A;  3PKI A;  1LKP A;  1FHH A;  1OWC A;  2M4V A;  1SMU A;  1S24 A;  4G6B A;  5EIN C;  1T9O A;  2JI3 A;  3KYX A;  5IY0 A;  1B71 A;  2DSX A;  2JI1 A;  1JYB A;  4JAF A;  4B8C D;  2PSM C;  1ZRP A;  5JVH 1;  2C6B A;  4XGH A;  5AI2 A;  1R0H A;  4XXB B;  2A68 D;  1OWB A;  1VZI A;  4K9F A;  1LTL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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