2NVQL

Rna polymerase ii elongation complex in 150 mm mg+2 with 2'dutp
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2nvqL00
3GTOL 4BY1L 1TWCL 3HOVL 1WCML 3M4OL 2R7ZL 3FKIL 5C44L 3GTLL 2E2JL 1TWFL 2WAQP 4Y7NL 1TWAL 3PO2L 4A3FL 4A3ML 3GTPL 2YU9L 3RZOL 3HOZL 3S1NL 4AYBP 5IP9L 2NVQL 2E2HL 3GTQL 3S15L 1Y1VL 3K7AL 4C3HL 2B63L 3HOUL 5M5XL 2JA5L 1TWHL 2JA7L 4C2M1 2JA6L 2NVXL 5M3ML 5IYDL 4A3JL 5FLML 3H0GL 1I6HL 2R93L 5C4XL 3S1QL 4BY7L 1K83L 3GTJL 3S1RL 2R92L 3HKZP 1I50L 2WB1P 1TWGL 3PO3L 2VUML 4Y52L 4A3KL 4BBRL 4A3LL 4A3CL 3HOYL 4A3IL 5M3FL 2JA8L 3HOWL 5FJ8L 4C3IL 5C3EL 3GTKL 3HOXL 4A3BL 3I4NL 1SFOL 4BBSL 3GTGL 2PMZP 3S17L 3CQZL 3S16L 4X6AL 4BXXL 4A3EL 1R9TL 4A3GL 2E2IL 4C3JL 3S1ML 4QIWP 5IP7L 3GTML 2NVTL 3S2DL 3S2HL 5M5WL 2NVYL 5IYCL 1Y1WL 2Y0SP 5C4JL 3M3YL 1I3QL 3RZDL 3S14L 4A3DL 3I4ML 4A93L 3H3VM 5M5YL 5IYBL
chains in the Genus database with same CATH superfamily
3B0AB 1YUZA 2B5ID 3HOVL 1LKOA 2M4VA 5MLC3 1RWDA 2E2JL 4JADA 4Y7NL 1YV1A 2XJUA 3B08B 4AHWA 1ODHA 3GTPL 2KN9A 2YU9L 3SS2A 2HR5A 4XXBB 2LCQA 2E2HL 1PFVA 1Y1VL 5MF6A 3RZTA 2CKAA 1IU6A 1S30A 2JA7L 4C2M1 3LWPB 2R93L 2M6PA 2A68D 5C4XL 1QQTA 1BRFA 4AHZA 2C6AA 1BQ9A 1B2JA 1RDVA 2VUML 4Y52L 4A3LL 3P8BA 3KYUA 4JAFA 4AI2A 4AHYA 5EINC 4TPUA 2CR8A 1RDGA 4C3IL 3PKJA 1LKMA 3P2AA 2APOB 2NYDA 4AI1A 1SMWA 1VZHA 4BXXL 4A3EL 1R9TL 5JVG1 2E2IL 3S1ML 3GTML 3S2DL 1YK4A 5M5WL 3J7Y1 1RYQA 1Y1WL 2Y0SP 2ERSA 1LKPA 3MQKB 1IW7D 4BY1L 2R7ZL 3RZ6A 2VL6A 3MPSA 3K35A 2V3BB 1TWAL 3PO2L 1Z92B 4A3FL 4A3ML 2BE5D 1SMMA 3RZOL 4UY81 2K2DA 2M4YA 3VPBE 1NXEA 2L0ZA 1DX8A 3LWOB 4AHXA 3ZG6A 2C6BA 4C3HL 2V0FA 1TWHL 3PL5A 1T9PA 3JR7A 3KYYA 5M3ML 5IYDL 2PPTA 5EIOC 3H0GL 2O5JD 3S1QL 4BY7L 3GTJL 3S1RL 3HKZP 1E8JA 2XJQA 1FHHA 2RDVA 1VZGA 1YUXA 4A3CL 5GAEc 3QQCE 1R0FA 1RYTA 1H7VA 5MGNA 5M3FL 1R0GA 3A44A 1LTLA 3HOWL 5FJ8L 4LHLA 5GAGc 3HOXL 1SFOL 3FDJA 4ZN1B 5AI2A 3H9BA 5AN9H 3GTGL 4E6YA 5GAHc 2RFKB 2QL0A 3J7Z1 4QIWP 2MS3A 3LPEB 2NVTL 4ME3A 1BQ8A 2AYJA 1R0JA 1QYBA 1ZRPA 5C4JL 3LWVB 1I3QL 3S14L 3I4ML 1DVBA 4TVMA 5M5YL 2HVYC 2XJTA 5IYBL 1B13A 2Z3RB 4AI3A 2ZIXA 3GTOL 1TWCL 3PKIA 1WCML 5IY0A 3FKIL 1T9QA 1TWFL 1OWCA 1PFWA 2WAQP 8RXNA 2XJRA 6RXNA 3WWLA 3WWNB 3QVDA 4V196 3KYWA 3S1NL 4AYBP 1S2ZA 5AI3A 3H99A 2NVQL 3GTQL 3S15L 3K7AL 5M5XL 2JA5L 3PZAA 1T9OA 2JA6L 1JYBA 1F4LA 1NNQA 2GMGA 4ZN3B 1I6HL 3KYVA 1NXGA 1R0IA 3HJWB 2XJSA 3HJYB 1B71A 1BFYA 1TWGL 5MFPA 3IU3I 4K9FA 4A3KL 3HOYL 4G6BA 5K2ME 1PFYA 2JA8L 4U671 4JAEA 3GTKL 2DSXA 4A3BL 1YK5A 3I4NL 5RXNA 2V0EA 2PSMC 2ERJA 1PZXA 3S16L 4POFA 2PVXA 4C3JL 5IP7L 4B8CD 3RYGA 5IYCL 4YWMA 5DM61 2EY4E 3LWRB 1PFUA 1VCXA 2H12A 4AI0A 3PWFA 3LNLA 4A3DL 4A93L 1BE7A 2CKCA 2J9UB 4AR4A 1C09A 4GS7D 2Z3QB 2JI3A 3M4OL 7RXNA 2JI2A 5C44L 3GTLL 5JVH1 3HAXC 1WJVA 2PYAA 4YWLA 4JAGA 3HOZL 5IP9L 1B2OA 1FHMA 3PIO1 3PIP1 4AR3A 2M6OA 2XJPA 1R0HA 2B63L 3HOUL 5H1Sc 1IU5A 2NVXL 2A6HD 2PVEA 2AUSB 4A3JL 4WFN1 1SMUA 4XGHA 5FLML 2XJVA 1IROA 1QCVA 1K83L 4LHNA 2R92L 1I50L 1CADA 2WB1P 3PO3L 4BBRL 2AQCA 2A69D 3MSUA 4POGA 4A3IL 3NFPI 4RXNA 1P7PA 5C3EL 4AR6A 1CAAA 2A6ED 4BBSL 1IRNA 4AR5A 2PMZP 3S17L 3LWQB 3CQZL 1S24A 1OWBA 4X6AL 4A3GL 3H97A 3KYXA 5GADc 3S2HL 2NVYL 2KKDA 5MFZA 1VZIA 3M3YL 2JI1A 3H9CA 3RZDL 1RB9A 3H3VM 5DM71
chains in the Genus database with same CATH topology
3GTOL 4BY1L 1TWCL 3HOVL 1WCML 3M4OL 2R7ZL 3FKIL 5C44L 3GTLL 2E2JL 1TWFL 2WAQP 4Y7NL 1TWAL 3PO2L 4A3FL 4A3ML 3GTPL 2YU9L 3RZOL 3HOZL 3S1NL 4AYBP 5IP9L 2NVQL 2E2HL 3GTQL 3S15L 1Y1VL 3K7AL 4C3HL 2B63L 3HOUL 5M5XL 2JA5L 1TWHL 2JA7L 4C2M1 2JA6L 2NVXL 5M3ML 5IYDL 4A3JL 5FLML 3H0GL 1I6HL 2R93L 5C4XL 3S1QL 4BY7L 1K83L 3GTJL 3S1RL 2R92L 3HKZP 1I50L 2WB1P 1TWGL 3PO3L 2VUML 4Y52L 4A3KL 4BBRL 4A3LL 4A3CL 3HOYL 4A3IL 5M3FL 2JA8L 3HOWL 5FJ8L 4C3IL 5C3EL 3GTKL 3HOXL 4A3BL 3I4NL 1SFOL 4BBSL 3GTGL 2PMZP 3S17L 3CQZL 3S16L 4X6AL 4BXXL 4A3EL 1R9TL 4A3GL 2E2IL 4C3JL 3S1ML 4QIWP 5IP7L 3GTML 2NVTL 3S2DL 3S2HL 5M5WL 2NVYL 5IYCL 1Y1WL 2Y0SP 5C4JL 3M3YL 1I3QL 3RZDL 3S14L 4A3DL 3I4ML 4A93L 3H3VM 5M5YL 5IYBL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTO L;  4BY1 L;  1TWC L;  3HOV L;  1WCM L;  3M4O L;  2R7Z L;  3FKI L;  5C44 L;  3GTL L;  2E2J L;  1TWF L;  2WAQ P;  4Y7N L;  1TWA L;  3PO2 L;  4A3F L;  4A3M L;  3GTP L;  2YU9 L;  3RZO L;  3HOZ L;  3S1N L;  4AYB P;  5IP9 L;  2NVQ L;  2E2H L;  3GTQ L;  3S15 L;  1Y1V L;  3K7A L;  4C3H L;  2B63 L;  3HOU L;  5M5X L;  2JA5 L;  1TWH L;  2JA7 L;  4C2M 1;  2JA6 L;  2NVX L;  5M3M L;  5IYD L;  4A3J L;  5FLM L;  3H0G L;  1I6H L;  2R93 L;  5C4X L;  3S1Q L;  4BY7 L;  1K83 L;  3GTJ L;  3S1R L;  2R92 L;  3HKZ P;  1I50 L;  2WB1 P;  1TWG L;  3PO3 L;  2VUM L;  4Y52 L;  4A3K L;  4BBR L;  4A3L L;  4A3C L;  3HOY L;  4A3I L;  5M3F L;  2JA8 L;  3HOW L;  5FJ8 L;  4C3I L;  5C3E L;  3GTK L;  3HOX L;  4A3B L;  3I4N L;  1SFO L;  4BBS L;  3GTG L;  2PMZ P;  3S17 L;  3CQZ L;  3S16 L;  4X6A L;  4BXX L;  4A3E L;  1R9T L;  4A3G L;  2E2I L;  4C3J L;  3S1M L;  4QIW P;  5IP7 L;  3GTM L;  2NVT L;  3S2D L;  3S2H L;  5M5W L;  2NVY L;  5IYC L;  1Y1W L;  2Y0S P;  5C4J L;  3M3Y L;  1I3Q L;  3RZD L;  3S14 L;  4A3D L;  3I4M L;  4A93 L;  3H3V M;  5M5Y L;  5IYB L; 
#chains in the Genus database with same CATH topology
 3B0A B;  1YUZ A;  2B5I D;  3HOV L;  1LKO A;  2M4V A;  5MLC 3;  1RWD A;  2E2J L;  4JAD A;  4Y7N L;  1YV1 A;  2XJU A;  3B08 B;  4AHW A;  1ODH A;  3GTP L;  2KN9 A;  2YU9 L;  3SS2 A;  2HR5 A;  4XXB B;  2LCQ A;  2E2H L;  1PFV A;  1Y1V L;  5MF6 A;  3RZT A;  2CKA A;  1IU6 A;  1S30 A;  2JA7 L;  4C2M 1;  3LWP B;  2R93 L;  2M6P A;  2A68 D;  5C4X L;  1QQT A;  1BRF A;  4AHZ A;  2C6A A;  1BQ9 A;  1B2J A;  1RDV A;  2VUM L;  4Y52 L;  4A3L L;  3P8B A;  3KYU A;  4JAF A;  4AI2 A;  4AHY A;  5EIN C;  4TPU A;  2CR8 A;  1RDG A;  4C3I L;  3PKJ A;  1LKM A;  3P2A A;  2APO B;  2NYD A;  4AI1 A;  1SMW A;  1VZH A;  4BXX L;  4A3E L;  1R9T L;  5JVG 1;  2E2I L;  3S1M L;  3GTM L;  3S2D L;  1YK4 A;  5M5W L;  3J7Y 1;  1RYQ A;  1Y1W L;  2Y0S P;  2ERS A;  1LKP A;  3MQK B;  1IW7 D;  4BY1 L;  2R7Z L;  3RZ6 A;  2VL6 A;  3MPS A;  3K35 A;  2V3B B;  1TWA L;  3PO2 L;  1Z92 B;  4A3F L;  4A3M L;  2BE5 D;  1SMM A;  3RZO L;  4UY8 1;  2K2D A;  2M4Y A;  3VPB E;  1NXE A;  2L0Z A;  1DX8 A;  3LWO B;  4AHX A;  3ZG6 A;  2C6B A;  4C3H L;  2V0F A;  1TWH L;  3PL5 A;  1T9P A;  3JR7 A;  3KYY A;  5M3M L;  5IYD L;  2PPT A;  5EIO C;  3H0G L;  2O5J D;  3S1Q L;  4BY7 L;  3GTJ L;  3S1R L;  3HKZ P;  1E8J A;  2XJQ A;  1FHH A;  2RDV A;  1VZG A;  1YUX A;  4A3C L;  5GAE c;  3QQC E;  1R0F A;  1RYT A;  1H7V A;  5MGN A;  5M3F L;  1R0G A;  3A44 A;  1LTL A;  3HOW L;  5FJ8 L;  4LHL A;  5GAG c;  3HOX L;  1SFO L;  3FDJ A;  4ZN1 B;  5AI2 A;  3H9B A;  5AN9 H;  3GTG L;  4E6Y A;  5GAH c;  2RFK B;  2QL0 A;  3J7Z 1;  4QIW P;  2MS3 A;  3LPE B;  2NVT L;  4ME3 A;  1BQ8 A;  2AYJ A;  1R0J A;  1QYB A;  1ZRP A;  5C4J L;  3LWV B;  1I3Q L;  3S14 L;  3I4M L;  1DVB A;  4TVM A;  5M5Y L;  2HVY C;  2XJT A;  5IYB L;  1B13 A;  2Z3R B;  4AI3 A;  2ZIX A;  3GTO L;  1TWC L;  3PKI A;  1WCM L;  5IY0 A;  3FKI L;  1T9Q A;  1TWF L;  1OWC A;  1PFW A;  2WAQ P;  8RXN A;  2XJR A;  6RXN A;  3WWL A;  3WWN B;  3QVD A;  4V19 6;  3KYW A;  3S1N L;  4AYB P;  1S2Z A;  5AI3 A;  3H99 A;  2NVQ L;  3GTQ L;  3S15 L;  3K7A L;  5M5X L;  2JA5 L;  3PZA A;  1T9O A;  2JA6 L;  1JYB A;  1F4L A;  1NNQ A;  2GMG A;  4ZN3 B;  1I6H L;  3KYV A;  1NXG A;  1R0I A;  3HJW B;  2XJS A;  3HJY B;  1B71 A;  1BFY A;  1TWG L;  5MFP A;  3IU3 I;  4K9F A;  4A3K L;  3HOY L;  4G6B A;  5K2M E;  1PFY A;  2JA8 L;  4U67 1;  4JAE A;  3GTK L;  2DSX A;  4A3B L;  1YK5 A;  3I4N L;  5RXN A;  2V0E A;  2PSM C;  2ERJ A;  1PZX A;  3S16 L;  4POF A;  2PVX A;  4C3J L;  5IP7 L;  4B8C D;  3RYG A;  5IYC L;  4YWM A;  5DM6 1;  2EY4 E;  3LWR B;  1PFU A;  1VCX A;  2H12 A;  4AI0 A;  3PWF A;  3LNL A;  4A3D L;  4A93 L;  1BE7 A;  2CKC A;  2J9U B;  4AR4 A;  1C09 A;  4GS7 D;  2Z3Q B;  2JI3 A;  3M4O L;  7RXN A;  2JI2 A;  5C44 L;  3GTL L;  5JVH 1;  3HAX C;  1WJV A;  2PYA A;  4YWL A;  4JAG A;  3HOZ L;  5IP9 L;  1B2O A;  1FHM A;  3PIO 1;  3PIP 1;  4AR3 A;  2M6O A;  2XJP A;  1R0H A;  2B63 L;  3HOU L;  5H1S c;  1IU5 A;  2NVX L;  2A6H D;  2PVE A;  2AUS B;  4A3J L;  4WFN 1;  1SMU A;  4XGH A;  5FLM L;  2XJV A;  1IRO A;  1QCV A;  1K83 L;  4LHN A;  2R92 L;  1I50 L;  1CAD A;  2WB1 P;  3PO3 L;  4BBR L;  2AQC A;  2A69 D;  3MSU A;  4POG A;  4A3I L;  3NFP I;  4RXN A;  1P7P A;  5C3E L;  4AR6 A;  1CAA A;  2A6E D;  4BBS L;  1IRN A;  4AR5 A;  2PMZ P;  3S17 L;  3LWQ B;  3CQZ L;  1S24 A;  1OWB A;  4X6A L;  4A3G L;  3H97 A;  3KYX A;  5GAD c;  3S2H L;  2NVY L;  2KKD A;  5MFZ A;  1VZI A;  3M3Y L;  2JI1 A;  3H9C A;  3RZD L;  1RB9 A;  3H3V M;  5DM7 1; 
#chains in the Genus database with same CATH homology
 3GTO L;  4BY1 L;  1TWC L;  3HOV L;  1WCM L;  3M4O L;  2R7Z L;  3FKI L;  5C44 L;  3GTL L;  2E2J L;  1TWF L;  2WAQ P;  4Y7N L;  1TWA L;  3PO2 L;  4A3F L;  4A3M L;  3GTP L;  2YU9 L;  3RZO L;  3HOZ L;  3S1N L;  4AYB P;  5IP9 L;  2NVQ L;  2E2H L;  3GTQ L;  3S15 L;  1Y1V L;  3K7A L;  4C3H L;  2B63 L;  3HOU L;  5M5X L;  2JA5 L;  1TWH L;  2JA7 L;  4C2M 1;  2JA6 L;  2NVX L;  5M3M L;  5IYD L;  4A3J L;  5FLM L;  3H0G L;  1I6H L;  2R93 L;  5C4X L;  3S1Q L;  4BY7 L;  1K83 L;  3GTJ L;  3S1R L;  2R92 L;  3HKZ P;  1I50 L;  2WB1 P;  1TWG L;  3PO3 L;  2VUM L;  4Y52 L;  4A3K L;  4BBR L;  4A3L L;  4A3C L;  3HOY L;  4A3I L;  5M3F L;  2JA8 L;  3HOW L;  5FJ8 L;  4C3I L;  5C3E L;  3GTK L;  3HOX L;  4A3B L;  3I4N L;  1SFO L;  4BBS L;  3GTG L;  2PMZ P;  3S17 L;  3CQZ L;  3S16 L;  4X6A L;  4BXX L;  4A3E L;  1R9T L;  4A3G L;  2E2I L;  4C3J L;  3S1M L;  4QIW P;  5IP7 L;  3GTM L;  2NVT L;  3S2D L;  3S2H L;  5M5W L;  2NVY L;  5IYC L;  1Y1W L;  2Y0S P;  5C4J L;  3M3Y L;  1I3Q L;  3RZD L;  3S14 L;  4A3D L;  3I4M L;  4A93 L;  3H3V M;  5M5Y L;  5IYB L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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