2NVTL

Rna polymerase ii elongation complex in 150 mm mg+2 with gmpcpp
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3'
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2nvtL00
2NVQL 3HOYL 1Y1VL 4C3JL 2E2IL 4Y7NL 3CQZL 3K7AL 1SFOL 4A3ML 3M3YL 3I4ML 4A3LL 1Y1WL 5M5WL 2NVXL 5IP9L 1TWHL 5IP7L 5C44L 2WB1P 1I3QL 5FLML 2WAQP 1R9TL 2R93L 2E2HL 5M3ML 4A3KL 3S1RL 4BBRL 3S15L 5C3EL 3HOVL 1K83L 3GTOL 3H0GL 3HOWL 4Y52L 1TWFL 4BXXL 5IYDL 4C2M1 5M5YL 2R7ZL 5M5XL 3S17L 2JA7L 2JA8L 2NVYL 5C4XL 3I4NL 4A3BL 2B63L 2YU9L 4A3CL 3PO2L 4C3IL 3H3VM 1TWCL 3GTML 2PMZP 4BY7L 1I6HL 2R92L 2JA6L 3RZDL 4A3FL 5M3FL 4X6AL 3GTKL 4AYBP 3M4OL 4A3DL 3PO3L 3HOZL 5IYBL 1WCML 3FKIL 3HOUL 4BBSL 5C4JL 3S2DL 3S1QL 2E2JL 2Y0SP 3GTGL 3S16L 4A3GL 5FJ8L 4C3HL 3S1ML 3HOXL 1TWGL 3GTJL 5IYCL 3S14L 4A3IL 3HKZP 2JA5L 4A3JL 3GTPL 3GTLL 4A93L 4QIWP 1TWAL 2VUML 3RZOL 4BY1L 3GTQL 2NVTL 3S2HL 4A3EL 3S1NL 1I50L
chains in the Genus database with same CATH superfamily
2RDVA 2NVQL 1Y1VL 4C3JL 3FDJA 1IW7D 1SFOL 1RYQA 1VZIA 4AR5A 2PPTA 5IP7L 3WWNB 2WB1P 3P8BA 4LHNA 3A44A 1P7PA 3KYUA 1F4LA 1R0FA 3S15L 4JADA 4RXNA 3PZAA 4BXXL 4AR6A 5JVG1 1IU5A 5AI2A 1VZGA 3H9CA 1BE7A 1VZHA 3IU3I 3LWRB 1PFVA 5EIOC 4AI0A 1YV1A 1T9PA 2XJSA 5C4XL 1PFWA 4A3BL 2V0FA 1H7VA 6RXNA 1CAAA 1S24A 3RZDL 3WWLA 4AYBP 3M4OL 4A3DL 1YUXA 3PO3L 1WCML 1PFUA 3H9BA 4AR4A 5IY0A 2KKDA 2RFKB 3K35A 1RDVA 2M6OA 4AI1A 3VPBE 3P2AA 3PWFA 3SS2A 4QIWP 2CKAA 1DVBA 3MPSA 2A6ED 3GTQL 2NVTL 2XJTA 2PVEA 4A3EL 2PVXA 3HOYL 2E2IL 3CQZL 2ZIXA 3K7AL 2V0EA 3B08B 2A6HD 4A3LL 1E8JA 1Y1WL 4U671 1R0JA 2KN9A 3PIP1 1NXEA 1TWHL 1LKMA 1I3QL 1B2JA 2AYJA 4ZN1B 2M6PA 1C09A 2E2HL 5MLC3 1BFYA 3S1RL 2PYAA 4XGHA 1QYBA 5EINC 4ME3A 5GAGc 5K2ME 5M5YL 1YUZA 1R0IA 5M5XL 3S17L 2M4VA 2LCQA 2K2DA 2EY4E 1WJVA 2GMGA 2XJUA 3I4NL 2YU9L 2B63L 3PO2L 1ODHA 1IROA 3GTML 2R92L 2JA6L 2XJQA 5M3FL 5GAEc 4V196 1NNQA 5RXNA 2PSMC 3KYXA 5IYBL 3FKIL 2MS3A 3HAXC 1R0GA 1SMMA 4JAGA 4A3GL 5FJ8L 3LPEB 3J7Z1 4TPUA 2JI1A 4AHZA 3HJWB 3RZTA 1LTLA 5IYCL 1S2ZA 5GAHc 3ZG6A 1DX8A 4AR3A 2VUML 3RZOL 3PKIA 3S2HL 3PIO1 1CADA 5H1Sc 4ZN3B 4YWLA 4POGA 2JI3A 5M5WL 5IP9L 3KYYA 5DM61 1LKPA 4AHXA 2WAQP 1FHMA 2BE5D 5M3ML 2A69D 3HOVL 3GTOL 5GADc 1TWFL 4C2M1 3MQKB 2R7ZL 2XJVA 4AI3A 1BQ8A 2JA8L 2NVYL 4AHWA 1SMUA 1PZXA 5AN9H 2J9UB 3H3VM 3H97A 1T9OA 2PMZP 4TVMA 3H99A 1B71A 1JYBA 5AI3A 4X6AL 2XJPA 3GTKL 5MF6A 1PFYA 2DSXA 1LKOA 1BRFA 3HOUL 4BBSL 5MFZA 5C4JL 3S2DL 3S1QL 3NFPI 2Y0SP 3QQCE 3LWOB 3GTGL 4AI2A 3S16L 2L0ZA 3S1ML 1B2OA 3HJYB 3GTJL 4A3JL 2APOB 2A68D 3GTPL 3GTLL 4LHLA 1TWAL 2VL6A 1IU6A 2M4YA 4E6YA 4B8CD 4XXBB 4BY1L 1OWBA 4Y52L 3PL5A 4Y7NL 2HR5A 4A3ML 3M3YL 2H12A 4GS7D 3I4ML 7RXNA 2CR8A 1YK5A 1R0HA 1SMWA 3LNLA 1RDGA 1S30A 2NVXL 5C44L 1RB9A 4YWMA 5FLML 3LWPB 5MGNA 1OWCA 4K9FA 3KYVA 1R9TL 2R93L 3QVDA 1RYTA 1NXGA 1YK4A 4A3KL 2JI2A 4JAEA 4BBRL 5C3EL 1K83L 1ZRPA 2B5ID 1RWDA 3H0GL 3HOWL 3KYWA 3MSUA 4WFN1 5IYDL 2ERSA 1IRNA 3B0AB 3J7Y1 1BQ9A 2JA7L 1Z92B 2C6AA 2C6BA 2Z3QB 3RYGA 4A3CL 5DM71 4C3IL 3JR7A 1TWCL 4BY7L 1I6HL 8RXNA 4A3FL 3LWQB 2Z3RB 2V3BB 3HOZL 1VCXA 2AUSB 2HVYC 2QL0A 5JVH1 2AQCA 2E2JL 4JAFA 1T9QA 1QQTA 2CKCA 4G6BA 4POFA 4C3HL 3HOXL 1TWGL 1QCVA 2XJRA 1FHHA 3S14L 4A3IL 3HKZP 2JA5L 1B13A 2ERJA 5MFPA 4UY81 4A93L 3PKJA 3LWVB 2O5JD 2NYDA 3RZ6A 4AHYA 3S1NL 1I50L
chains in the Genus database with same CATH topology
2NVQL 3HOYL 1Y1VL 4C3JL 2E2IL 4Y7NL 3CQZL 3K7AL 1SFOL 4A3ML 3M3YL 3I4ML 4A3LL 1Y1WL 5M5WL 2NVXL 5IP9L 1TWHL 5IP7L 5C44L 2WB1P 1I3QL 5FLML 2WAQP 1R9TL 2R93L 2E2HL 5M3ML 4A3KL 3S1RL 4BBRL 3S15L 5C3EL 3HOVL 1K83L 3GTOL 3H0GL 3HOWL 4Y52L 1TWFL 4BXXL 5IYDL 4C2M1 5M5YL 2R7ZL 5M5XL 3S17L 2JA7L 2JA8L 2NVYL 5C4XL 3I4NL 4A3BL 2B63L 2YU9L 4A3CL 3PO2L 4C3IL 3H3VM 1TWCL 3GTML 2PMZP 4BY7L 1I6HL 2R92L 2JA6L 3RZDL 4A3FL 5M3FL 4X6AL 3GTKL 4AYBP 3M4OL 4A3DL 3PO3L 3HOZL 5IYBL 1WCML 3FKIL 3HOUL 4BBSL 5C4JL 3S2DL 3S1QL 2E2JL 2Y0SP 3GTGL 3S16L 4A3GL 5FJ8L 4C3HL 3S1ML 3HOXL 1TWGL 3GTJL 5IYCL 3S14L 4A3IL 3HKZP 2JA5L 4A3JL 3GTPL 3GTLL 4A93L 4QIWP 1TWAL 2VUML 3RZOL 4BY1L 3GTQL 2NVTL 3S2HL 4A3EL 3S1NL 1I50L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVQ L;  3HOY L;  1Y1V L;  4C3J L;  2E2I L;  4Y7N L;  3CQZ L;  3K7A L;  1SFO L;  4A3M L;  3M3Y L;  3I4M L;  4A3L L;  1Y1W L;  5M5W L;  2NVX L;  5IP9 L;  1TWH L;  5IP7 L;  5C44 L;  2WB1 P;  1I3Q L;  5FLM L;  2WAQ P;  1R9T L;  2R93 L;  2E2H L;  5M3M L;  4A3K L;  3S1R L;  4BBR L;  3S15 L;  5C3E L;  3HOV L;  1K83 L;  3GTO L;  3H0G L;  3HOW L;  4Y52 L;  1TWF L;  4BXX L;  5IYD L;  4C2M 1;  5M5Y L;  2R7Z L;  5M5X L;  3S17 L;  2JA7 L;  2JA8 L;  2NVY L;  5C4X L;  3I4N L;  4A3B L;  2B63 L;  2YU9 L;  4A3C L;  3PO2 L;  4C3I L;  3H3V M;  1TWC L;  3GTM L;  2PMZ P;  4BY7 L;  1I6H L;  2R92 L;  2JA6 L;  3RZD L;  4A3F L;  5M3F L;  4X6A L;  3GTK L;  4AYB P;  3M4O L;  4A3D L;  3PO3 L;  3HOZ L;  5IYB L;  1WCM L;  3FKI L;  3HOU L;  4BBS L;  5C4J L;  3S2D L;  3S1Q L;  2E2J L;  2Y0S P;  3GTG L;  3S16 L;  4A3G L;  5FJ8 L;  4C3H L;  3S1M L;  3HOX L;  1TWG L;  3GTJ L;  5IYC L;  3S14 L;  4A3I L;  3HKZ P;  2JA5 L;  4A3J L;  3GTP L;  3GTL L;  4A93 L;  4QIW P;  1TWA L;  2VUM L;  3RZO L;  4BY1 L;  3GTQ L;  2NVT L;  3S2H L;  4A3E L;  3S1N L;  1I50 L; 
#chains in the Genus database with same CATH topology
 2RDV A;  2NVQ L;  1Y1V L;  4C3J L;  3FDJ A;  1IW7 D;  1SFO L;  1RYQ A;  1VZI A;  4AR5 A;  2PPT A;  5IP7 L;  3WWN B;  2WB1 P;  3P8B A;  4LHN A;  3A44 A;  1P7P A;  3KYU A;  1F4L A;  1R0F A;  3S15 L;  4JAD A;  4RXN A;  3PZA A;  4BXX L;  4AR6 A;  5JVG 1;  1IU5 A;  5AI2 A;  1VZG A;  3H9C A;  1BE7 A;  1VZH A;  3IU3 I;  3LWR B;  1PFV A;  5EIO C;  4AI0 A;  1YV1 A;  1T9P A;  2XJS A;  5C4X L;  1PFW A;  4A3B L;  2V0F A;  1H7V A;  6RXN A;  1CAA A;  1S24 A;  3RZD L;  3WWL A;  4AYB P;  3M4O L;  4A3D L;  1YUX A;  3PO3 L;  1WCM L;  1PFU A;  3H9B A;  4AR4 A;  5IY0 A;  2KKD A;  2RFK B;  3K35 A;  1RDV A;  2M6O A;  4AI1 A;  3VPB E;  3P2A A;  3PWF A;  3SS2 A;  4QIW P;  2CKA A;  1DVB A;  3MPS A;  2A6E D;  3GTQ L;  2NVT L;  2XJT A;  2PVE A;  4A3E L;  2PVX A;  3HOY L;  2E2I L;  3CQZ L;  2ZIX A;  3K7A L;  2V0E A;  3B08 B;  2A6H D;  4A3L L;  1E8J A;  1Y1W L;  4U67 1;  1R0J A;  2KN9 A;  3PIP 1;  1NXE A;  1TWH L;  1LKM A;  1I3Q L;  1B2J A;  2AYJ A;  4ZN1 B;  2M6P A;  1C09 A;  2E2H L;  5MLC 3;  1BFY A;  3S1R L;  2PYA A;  4XGH A;  1QYB A;  5EIN C;  4ME3 A;  5GAG c;  5K2M E;  5M5Y L;  1YUZ A;  1R0I A;  5M5X L;  3S17 L;  2M4V A;  2LCQ A;  2K2D A;  2EY4 E;  1WJV A;  2GMG A;  2XJU A;  3I4N L;  2YU9 L;  2B63 L;  3PO2 L;  1ODH A;  1IRO A;  3GTM L;  2R92 L;  2JA6 L;  2XJQ A;  5M3F L;  5GAE c;  4V19 6;  1NNQ A;  5RXN A;  2PSM C;  3KYX A;  5IYB L;  3FKI L;  2MS3 A;  3HAX C;  1R0G A;  1SMM A;  4JAG A;  4A3G L;  5FJ8 L;  3LPE B;  3J7Z 1;  4TPU A;  2JI1 A;  4AHZ A;  3HJW B;  3RZT A;  1LTL A;  5IYC L;  1S2Z A;  5GAH c;  3ZG6 A;  1DX8 A;  4AR3 A;  2VUM L;  3RZO L;  3PKI A;  3S2H L;  3PIO 1;  1CAD A;  5H1S c;  4ZN3 B;  4YWL A;  4POG A;  2JI3 A;  5M5W L;  5IP9 L;  3KYY A;  5DM6 1;  1LKP A;  4AHX A;  2WAQ P;  1FHM A;  2BE5 D;  5M3M L;  2A69 D;  3HOV L;  3GTO L;  5GAD c;  1TWF L;  4C2M 1;  3MQK B;  2R7Z L;  2XJV A;  4AI3 A;  1BQ8 A;  2JA8 L;  2NVY L;  4AHW A;  1SMU A;  1PZX A;  5AN9 H;  2J9U B;  3H3V M;  3H97 A;  1T9O A;  2PMZ P;  4TVM A;  3H99 A;  1B71 A;  1JYB A;  5AI3 A;  4X6A L;  2XJP A;  3GTK L;  5MF6 A;  1PFY A;  2DSX A;  1LKO A;  1BRF A;  3HOU L;  4BBS L;  5MFZ A;  5C4J L;  3S2D L;  3S1Q L;  3NFP I;  2Y0S P;  3QQC E;  3LWO B;  3GTG L;  4AI2 A;  3S16 L;  2L0Z A;  3S1M L;  1B2O A;  3HJY B;  3GTJ L;  4A3J L;  2APO B;  2A68 D;  3GTP L;  3GTL L;  4LHL A;  1TWA L;  2VL6 A;  1IU6 A;  2M4Y A;  4E6Y A;  4B8C D;  4XXB B;  4BY1 L;  1OWB A;  4Y52 L;  3PL5 A;  4Y7N L;  2HR5 A;  4A3M L;  3M3Y L;  2H12 A;  4GS7 D;  3I4M L;  7RXN A;  2CR8 A;  1YK5 A;  1R0H A;  1SMW A;  3LNL A;  1RDG A;  1S30 A;  2NVX L;  5C44 L;  1RB9 A;  4YWM A;  5FLM L;  3LWP B;  5MGN A;  1OWC A;  4K9F A;  3KYV A;  1R9T L;  2R93 L;  3QVD A;  1RYT A;  1NXG A;  1YK4 A;  4A3K L;  2JI2 A;  4JAE A;  4BBR L;  5C3E L;  1K83 L;  1ZRP A;  2B5I D;  1RWD A;  3H0G L;  3HOW L;  3KYW A;  3MSU A;  4WFN 1;  5IYD L;  2ERS A;  1IRN A;  3B0A B;  3J7Y 1;  1BQ9 A;  2JA7 L;  1Z92 B;  2C6A A;  2C6B A;  2Z3Q B;  3RYG A;  4A3C L;  5DM7 1;  4C3I L;  3JR7 A;  1TWC L;  4BY7 L;  1I6H L;  8RXN A;  4A3F L;  3LWQ B;  2Z3R B;  2V3B B;  3HOZ L;  1VCX A;  2AUS B;  2HVY C;  2QL0 A;  5JVH 1;  2AQC A;  2E2J L;  4JAF A;  1T9Q A;  1QQT A;  2CKC A;  4G6B A;  4POF A;  4C3H L;  3HOX L;  1TWG L;  1QCV A;  2XJR A;  1FHH A;  3S14 L;  4A3I L;  3HKZ P;  2JA5 L;  1B13 A;  2ERJ A;  5MFP A;  4UY8 1;  4A93 L;  3PKJ A;  3LWV B;  2O5J D;  2NYD A;  3RZ6 A;  4AHY A;  3S1N L;  1I50 L; 
#chains in the Genus database with same CATH homology
 2NVQ L;  3HOY L;  1Y1V L;  4C3J L;  2E2I L;  4Y7N L;  3CQZ L;  3K7A L;  1SFO L;  4A3M L;  3M3Y L;  3I4M L;  4A3L L;  1Y1W L;  5M5W L;  2NVX L;  5IP9 L;  1TWH L;  5IP7 L;  5C44 L;  2WB1 P;  1I3Q L;  5FLM L;  2WAQ P;  1R9T L;  2R93 L;  2E2H L;  5M3M L;  4A3K L;  3S1R L;  4BBR L;  3S15 L;  5C3E L;  3HOV L;  1K83 L;  3GTO L;  3H0G L;  3HOW L;  4Y52 L;  1TWF L;  4BXX L;  5IYD L;  4C2M 1;  5M5Y L;  2R7Z L;  5M5X L;  3S17 L;  2JA7 L;  2JA8 L;  2NVY L;  5C4X L;  3I4N L;  4A3B L;  2B63 L;  2YU9 L;  4A3C L;  3PO2 L;  4C3I L;  3H3V M;  1TWC L;  3GTM L;  2PMZ P;  4BY7 L;  1I6H L;  2R92 L;  2JA6 L;  3RZD L;  4A3F L;  5M3F L;  4X6A L;  3GTK L;  4AYB P;  3M4O L;  4A3D L;  3PO3 L;  3HOZ L;  5IYB L;  1WCM L;  3FKI L;  3HOU L;  4BBS L;  5C4J L;  3S2D L;  3S1Q L;  2E2J L;  2Y0S P;  3GTG L;  3S16 L;  4A3G L;  5FJ8 L;  4C3H L;  3S1M L;  3HOX L;  1TWG L;  3GTJ L;  5IYC L;  3S14 L;  4A3I L;  3HKZ P;  2JA5 L;  4A3J L;  3GTP L;  3GTL L;  4A93 L;  4QIW P;  1TWA L;  2VUM L;  3RZO L;  4BY1 L;  3GTQ L;  2NVT L;  3S2H L;  4A3E L;  3S1N L;  1I50 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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