2NVXL

Rna polymerase ii elongation complex in 5 mm mg+2 with 2'-dutp
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2nvxL00
5IP9L 4A3LL 3GTOL 1TWGL 1I6HL 4C2M1 3S15L 1TWCL 3S14L 4A93L 5M3FL 3H3VM 3K7AL 3HOXL 1SFOL 3HOYL 5C44L 3GTKL 2B63L 3S1RL 2R93L 4AYBP 2YU9L 5C4JL 2Y0SP 4QIWP 4BY1L 5IP7L 4A3IL 2R92L 2PMZP 4A3EL 2JA7L 3HOZL 4BY7L 4C3JL 3GTLL 2WB1P 3FKIL 3HOUL 1Y1WL 2JA5L 5C4XL 3CQZL 3GTGL 1Y1VL 3GTPL 5FLML 4A3DL 2VUML 2NVXL 3M3YL 1I3QL 3S1ML 4Y7NL 4A3BL 5IYBL 3RZOL 4C3HL 1TWHL 3I4NL 2NVYL 5M5XL 4BBSL 5FJ8L 1WCML 3S1QL 4BXXL 5IYCL 1I50L 5M5WL 5C3EL 4A3FL 3HOVL 3S16L 2E2JL 3S1NL 2NVQL 3I4ML 3M4OL 3S17L 1K83L 4C3IL 4X6AL 5IYDL 3HKZP 3GTML 3PO2L 2R7ZL 3H0GL 2JA6L 4BBRL 3S2HL 4A3GL 4A3KL 3S2DL 1TWAL 5M3ML 3GTJL 4A3CL 4Y52L 2WAQP 2E2IL 3RZDL 2NVTL 3GTQL 4A3JL 4A3ML 3PO3L 1R9TL 3HOWL 2JA8L 5M5YL 2E2HL 1TWFL
chains in the Genus database with same CATH superfamily
5IP9L 3GTOL 1TWGL 2C6BA 1IRNA 3S15L 1B2OA 2LCQA 1DVBA 3K7AL 3HOXL 1SFOL 3LWRB 2ERJA 1BQ9A 2Y0SP 3H9CA 1NNQA 1IU6A 3HAXC 1B71A 1SMMA 4B8CD 4A3IL 5JVG1 3J7Z1 4AI3A 2M4YA 2XJQA 3PIO1 1LTLA 1LKMA 2ZIXA 4YWLA 1CAAA 3GTLL 4AI2A 3CQZL 4A3DL 1QCVA 4JAEA 1NXGA 4AHYA 1TWHL 4JAFA 3LWQB 2CR8A 4YWMA 1RWDA 4ZN3B 5H1Sc 1SMWA 1YV1A 3S1QL 1BRFA 1WJVA 5IYCL 1FHHA 2RDVA 2XJSA 4TVMA 5AI3A 2E2JL 3S1NL 3I4ML 3H9BA 4RXNA 5K2ME 3H0GL 5AN9H 1TWAL 5M3ML 2QL0A 3FDJA 4A3JL 1DX8A 4A3ML 2PPTA 1S24A 1R0FA 4U671 2JA8L 1LKOA 5MF6A 1F4LA 2VL6A 1TWFL 2CKCA 4K9FA 2CKAA 4A93L 5M3FL 4JAGA 3GTKL 3KYWA 5GAEc 5MFPA 2B5ID 5IP7L 1E8JA 5AI2A 2XJTA 2R92L 2PMZP 2PVXA 5EINC 4A3EL 2O5JD 3PIP1 1T9OA 1SMUA 2HVYC 1RYQA 2L0ZA 5IY0A 3FKIL 1ODHA 1Y1VL 2KN9A 1BQ8A 2AUSB 2VUML 5MGNA 3RYGA 2NVXL 3M3YL 1I3QL 4Y7NL 4A3BL 5IYBL 5GAGc 1VZIA 1YK4A 1BFYA 4AHWA 1S2ZA 5C3EL 4A3FL 2APOB 2NVQL 1K83L 1T9QA 3HKZP 4ME3A 1OWCA 5JVH1 3GTML 2R7ZL 3PKJA 1S30A 2JI1A 1RDGA 4BBRL 3S2HL 1QYBA 3S2DL 3B0AB 3GTJL 2WAQP 2E2IL 2NVTL 1R9TL 4E6YA 1PZXA 1R0GA 4A3LL 1I6HL 4C2M1 1TWCL 3KYUA 1YUXA 4LHLA 1ZRPA 4TPUA 4AHXA 2B63L 2A6ED 2NYDA 2R93L 4AYBP 1YUZA 2XJVA 2YU9L 3B08B 4QIWP 4BY1L 1PFUA 3WWLA 2MS3A 1IROA 2HR5A 3KYYA 2M6PA 5MFZA 3PKIA 3QQCE 3VPBE 4C3JL 3SS2A 1IW7D 3MSUA 4AR3A 1FHMA 1RYTA 2WB1P 2GMGA 4AI1A 3HOUL 1Y1WL 5C4XL 3GTGL 3GTPL 1RB9A 3J7Y1 3HJWB 2M4VA 3A44A 2BE5D 3S1ML 2M6OA 5DM71 4C3HL 2PSMC 1NXEA 6RXNA 2AYJA 7RXNA 3LWOB 5M5XL 1R0HA 2Z3RB 5FJ8L 4AI0A 1R0JA 2EY4E 2AQCA 1B13A 5M5WL 1B2JA 2PVEA 2XJPA 3HOVL 1YK5A 4XGHA 3M4OL 2C6AA 1RDVA 3RZTA 8RXNA 4X6AL 3K35A 3PO2L 2JA6L 1PFWA 5RXNA 1C09A 4A3CL 4Y52L 3IU3I 4LHNA 3RZDL 4G6BA 3PO3L 3NFPI 3P2AA 2XJRA 2E2HL 3LPEB 1VCXA 3JR7A 4WFN1 3S14L 1P7PA 3H3VM 2H12A 3KYVA 4JADA 3HOYL 5C44L 3ZG6A 4ZN1B 3S1RL 5C4JL 2V0EA 1PFYA 2RFKB 2V0FA 1H7VA 3H97A 4UY81 4V196 2KKDA 3MPSA 2JA7L 3HOZL 3P8BA 4BY7L 2V3BB 4GS7D 3HJYB 4AR5A 1QQTA 1R0IA 2XJUA 5EIOC 2J9UB 2JA5L 3QVDA 5FLML 1PFVA 2JI3A 1T9PA 2PYAA 3RZOL 3PL5A 3WWNB 3I4NL 2NVYL 5DM61 1JYBA 2A68D 3MQKB 3LNLA 3PWFA 5GADc 3RZ6A 2DSXA 5GAHc 4BBSL 4POFA 4XXBB 1WCML 1LKPA 2A69D 4AHZA 2ERSA 2JI2A 4BXXL 1I50L 2A6HD 4AR4A 5MLC3 3S16L 1OWBA 1VZGA 3S17L 2K2DA 4C3IL 2Z3QB 1CADA 1Z92B 5IYDL 3H99A 4A3GL 3PZAA 3LWVB 4A3KL 4AR6A 1BE7A 1IU5A 3LWPB 3GTQL 3HOWL 5M5YL 3KYXA 1VZHA 4POGA
chains in the Genus database with same CATH topology
5IP9L 4A3LL 3GTOL 1TWGL 1I6HL 4C2M1 3S15L 1TWCL 3S14L 4A93L 5M3FL 3H3VM 3K7AL 3HOXL 1SFOL 3HOYL 5C44L 3GTKL 2B63L 3S1RL 2R93L 4AYBP 2YU9L 5C4JL 2Y0SP 4QIWP 4BY1L 5IP7L 4A3IL 2R92L 2PMZP 4A3EL 2JA7L 3HOZL 4BY7L 4C3JL 3GTLL 2WB1P 3FKIL 3HOUL 1Y1WL 2JA5L 5C4XL 3CQZL 3GTGL 1Y1VL 3GTPL 5FLML 4A3DL 2VUML 2NVXL 3M3YL 1I3QL 3S1ML 4Y7NL 4A3BL 5IYBL 3RZOL 4C3HL 1TWHL 3I4NL 2NVYL 5M5XL 4BBSL 5FJ8L 1WCML 3S1QL 4BXXL 5IYCL 1I50L 5M5WL 5C3EL 4A3FL 3HOVL 3S16L 2E2JL 3S1NL 2NVQL 3I4ML 3M4OL 3S17L 1K83L 4C3IL 4X6AL 5IYDL 3HKZP 3GTML 3PO2L 2R7ZL 3H0GL 2JA6L 4BBRL 3S2HL 4A3GL 4A3KL 3S2DL 1TWAL 5M3ML 3GTJL 4A3CL 4Y52L 2WAQP 2E2IL 3RZDL 2NVTL 3GTQL 4A3JL 4A3ML 3PO3L 1R9TL 3HOWL 2JA8L 5M5YL 2E2HL 1TWFL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IP9 L;  4A3L L;  3GTO L;  1TWG L;  1I6H L;  4C2M 1;  3S15 L;  1TWC L;  3S14 L;  4A93 L;  5M3F L;  3H3V M;  3K7A L;  3HOX L;  1SFO L;  3HOY L;  5C44 L;  3GTK L;  2B63 L;  3S1R L;  2R93 L;  4AYB P;  2YU9 L;  5C4J L;  2Y0S P;  4QIW P;  4BY1 L;  5IP7 L;  4A3I L;  2R92 L;  2PMZ P;  4A3E L;  2JA7 L;  3HOZ L;  4BY7 L;  4C3J L;  3GTL L;  2WB1 P;  3FKI L;  3HOU L;  1Y1W L;  2JA5 L;  5C4X L;  3CQZ L;  3GTG L;  1Y1V L;  3GTP L;  5FLM L;  4A3D L;  2VUM L;  2NVX L;  3M3Y L;  1I3Q L;  3S1M L;  4Y7N L;  4A3B L;  5IYB L;  3RZO L;  4C3H L;  1TWH L;  3I4N L;  2NVY L;  5M5X L;  4BBS L;  5FJ8 L;  1WCM L;  3S1Q L;  4BXX L;  5IYC L;  1I50 L;  5M5W L;  5C3E L;  4A3F L;  3HOV L;  3S16 L;  2E2J L;  3S1N L;  2NVQ L;  3I4M L;  3M4O L;  3S17 L;  1K83 L;  4C3I L;  4X6A L;  5IYD L;  3HKZ P;  3GTM L;  3PO2 L;  2R7Z L;  3H0G L;  2JA6 L;  4BBR L;  3S2H L;  4A3G L;  4A3K L;  3S2D L;  1TWA L;  5M3M L;  3GTJ L;  4A3C L;  4Y52 L;  2WAQ P;  2E2I L;  3RZD L;  2NVT L;  3GTQ L;  4A3J L;  4A3M L;  3PO3 L;  1R9T L;  3HOW L;  2JA8 L;  5M5Y L;  2E2H L;  1TWF L; 
#chains in the Genus database with same CATH topology
 5IP9 L;  3GTO L;  1TWG L;  2C6B A;  1IRN A;  3S15 L;  1B2O A;  2LCQ A;  1DVB A;  3K7A L;  3HOX L;  1SFO L;  3LWR B;  2ERJ A;  1BQ9 A;  2Y0S P;  3H9C A;  1NNQ A;  1IU6 A;  3HAX C;  1B71 A;  1SMM A;  4B8C D;  4A3I L;  5JVG 1;  3J7Z 1;  4AI3 A;  2M4Y A;  2XJQ A;  3PIO 1;  1LTL A;  1LKM A;  2ZIX A;  4YWL A;  1CAA A;  3GTL L;  4AI2 A;  3CQZ L;  4A3D L;  1QCV A;  4JAE A;  1NXG A;  4AHY A;  1TWH L;  4JAF A;  3LWQ B;  2CR8 A;  4YWM A;  1RWD A;  4ZN3 B;  5H1S c;  1SMW A;  1YV1 A;  3S1Q L;  1BRF A;  1WJV A;  5IYC L;  1FHH A;  2RDV A;  2XJS A;  4TVM A;  5AI3 A;  2E2J L;  3S1N L;  3I4M L;  3H9B A;  4RXN A;  5K2M E;  3H0G L;  5AN9 H;  1TWA L;  5M3M L;  2QL0 A;  3FDJ A;  4A3J L;  1DX8 A;  4A3M L;  2PPT A;  1S24 A;  1R0F A;  4U67 1;  2JA8 L;  1LKO A;  5MF6 A;  1F4L A;  2VL6 A;  1TWF L;  2CKC A;  4K9F A;  2CKA A;  4A93 L;  5M3F L;  4JAG A;  3GTK L;  3KYW A;  5GAE c;  5MFP A;  2B5I D;  5IP7 L;  1E8J A;  5AI2 A;  2XJT A;  2R92 L;  2PMZ P;  2PVX A;  5EIN C;  4A3E L;  2O5J D;  3PIP 1;  1T9O A;  1SMU A;  2HVY C;  1RYQ A;  2L0Z A;  5IY0 A;  3FKI L;  1ODH A;  1Y1V L;  2KN9 A;  1BQ8 A;  2AUS B;  2VUM L;  5MGN A;  3RYG A;  2NVX L;  3M3Y L;  1I3Q L;  4Y7N L;  4A3B L;  5IYB L;  5GAG c;  1VZI A;  1YK4 A;  1BFY A;  4AHW A;  1S2Z A;  5C3E L;  4A3F L;  2APO B;  2NVQ L;  1K83 L;  1T9Q A;  3HKZ P;  4ME3 A;  1OWC A;  5JVH 1;  3GTM L;  2R7Z L;  3PKJ A;  1S30 A;  2JI1 A;  1RDG A;  4BBR L;  3S2H L;  1QYB A;  3S2D L;  3B0A B;  3GTJ L;  2WAQ P;  2E2I L;  2NVT L;  1R9T L;  4E6Y A;  1PZX A;  1R0G A;  4A3L L;  1I6H L;  4C2M 1;  1TWC L;  3KYU A;  1YUX A;  4LHL A;  1ZRP A;  4TPU A;  4AHX A;  2B63 L;  2A6E D;  2NYD A;  2R93 L;  4AYB P;  1YUZ A;  2XJV A;  2YU9 L;  3B08 B;  4QIW P;  4BY1 L;  1PFU A;  3WWL A;  2MS3 A;  1IRO A;  2HR5 A;  3KYY A;  2M6P A;  5MFZ A;  3PKI A;  3QQC E;  3VPB E;  4C3J L;  3SS2 A;  1IW7 D;  3MSU A;  4AR3 A;  1FHM A;  1RYT A;  2WB1 P;  2GMG A;  4AI1 A;  3HOU L;  1Y1W L;  5C4X L;  3GTG L;  3GTP L;  1RB9 A;  3J7Y 1;  3HJW B;  2M4V A;  3A44 A;  2BE5 D;  3S1M L;  2M6O A;  5DM7 1;  4C3H L;  2PSM C;  1NXE A;  6RXN A;  2AYJ A;  7RXN A;  3LWO B;  5M5X L;  1R0H A;  2Z3R B;  5FJ8 L;  4AI0 A;  1R0J A;  2EY4 E;  2AQC A;  1B13 A;  5M5W L;  1B2J A;  2PVE A;  2XJP A;  3HOV L;  1YK5 A;  4XGH A;  3M4O L;  2C6A A;  1RDV A;  3RZT A;  8RXN A;  4X6A L;  3K35 A;  3PO2 L;  2JA6 L;  1PFW A;  5RXN A;  1C09 A;  4A3C L;  4Y52 L;  3IU3 I;  4LHN A;  3RZD L;  4G6B A;  3PO3 L;  3NFP I;  3P2A A;  2XJR A;  2E2H L;  3LPE B;  1VCX A;  3JR7 A;  4WFN 1;  3S14 L;  1P7P A;  3H3V M;  2H12 A;  3KYV A;  4JAD A;  3HOY L;  5C44 L;  3ZG6 A;  4ZN1 B;  3S1R L;  5C4J L;  2V0E A;  1PFY A;  2RFK B;  2V0F A;  1H7V A;  3H97 A;  4UY8 1;  4V19 6;  2KKD A;  3MPS A;  2JA7 L;  3HOZ L;  3P8B A;  4BY7 L;  2V3B B;  4GS7 D;  3HJY B;  4AR5 A;  1QQT A;  1R0I A;  2XJU A;  5EIO C;  2J9U B;  2JA5 L;  3QVD A;  5FLM L;  1PFV A;  2JI3 A;  1T9P A;  2PYA A;  3RZO L;  3PL5 A;  3WWN B;  3I4N L;  2NVY L;  5DM6 1;  1JYB A;  2A68 D;  3MQK B;  3LNL A;  3PWF A;  5GAD c;  3RZ6 A;  2DSX A;  5GAH c;  4BBS L;  4POF A;  4XXB B;  1WCM L;  1LKP A;  2A69 D;  4AHZ A;  2ERS A;  2JI2 A;  4BXX L;  1I50 L;  2A6H D;  4AR4 A;  5MLC 3;  3S16 L;  1OWB A;  1VZG A;  3S17 L;  2K2D A;  4C3I L;  2Z3Q B;  1CAD A;  1Z92 B;  5IYD L;  3H99 A;  4A3G L;  3PZA A;  3LWV B;  4A3K L;  4AR6 A;  1BE7 A;  1IU5 A;  3LWP B;  3GTQ L;  3HOW L;  5M5Y L;  3KYX A;  1VZH A;  4POG A; 
#chains in the Genus database with same CATH homology
 5IP9 L;  4A3L L;  3GTO L;  1TWG L;  1I6H L;  4C2M 1;  3S15 L;  1TWC L;  3S14 L;  4A93 L;  5M3F L;  3H3V M;  3K7A L;  3HOX L;  1SFO L;  3HOY L;  5C44 L;  3GTK L;  2B63 L;  3S1R L;  2R93 L;  4AYB P;  2YU9 L;  5C4J L;  2Y0S P;  4QIW P;  4BY1 L;  5IP7 L;  4A3I L;  2R92 L;  2PMZ P;  4A3E L;  2JA7 L;  3HOZ L;  4BY7 L;  4C3J L;  3GTL L;  2WB1 P;  3FKI L;  3HOU L;  1Y1W L;  2JA5 L;  5C4X L;  3CQZ L;  3GTG L;  1Y1V L;  3GTP L;  5FLM L;  4A3D L;  2VUM L;  2NVX L;  3M3Y L;  1I3Q L;  3S1M L;  4Y7N L;  4A3B L;  5IYB L;  3RZO L;  4C3H L;  1TWH L;  3I4N L;  2NVY L;  5M5X L;  4BBS L;  5FJ8 L;  1WCM L;  3S1Q L;  4BXX L;  5IYC L;  1I50 L;  5M5W L;  5C3E L;  4A3F L;  3HOV L;  3S16 L;  2E2J L;  3S1N L;  2NVQ L;  3I4M L;  3M4O L;  3S17 L;  1K83 L;  4C3I L;  4X6A L;  5IYD L;  3HKZ P;  3GTM L;  3PO2 L;  2R7Z L;  3H0G L;  2JA6 L;  4BBR L;  3S2H L;  4A3G L;  4A3K L;  3S2D L;  1TWA L;  5M3M L;  3GTJ L;  4A3C L;  4Y52 L;  2WAQ P;  2E2I L;  3RZD L;  2NVT L;  3GTQ L;  4A3J L;  4A3M L;  3PO3 L;  1R9T L;  3HOW L;  2JA8 L;  5M5Y L;  2E2H L;  1TWF L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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