2NVYL

Rna polymerase ii form ii in 150 mm mn+2
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II largest subunit
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2006-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2nvyL00
4A3CL 2JA8L 4BY1L 5IYBL 3S15L 3M3YL 3S2HL 5M3FL 5M5XL 3HOZL 1SFOL 3FKIL 3GTKL 4BXXL 4A3FL 3I4ML 3M4OL 3CQZL 2NVXL 5FJ8L 3PO3L 4BY7L 3HOVL 2E2JL 3GTJL 4BBRL 1TWAL 3HOUL 3GTPL 3I4NL 3RZOL 4Y7NL 2NVQL 4A3JL 3GTQL 4A3BL 4X6AL 1I3QL 5M5WL 1Y1VL 1TWGL 1I50L 3HOYL 3RZDL 3S1NL 2WB1P 1Y1WL 3GTGL 2JA7L 3HKZP 4C3JL 3S1QL 1WCML 5FLML 2R92L 1I6HL 3H3VM 5C4JL 4A3DL 4A3ML 3K7AL 4AYBP 5C4XL 1TWHL 3S1ML 1R9TL 4A3EL 3S14L 2PMZP 4Y52L 5C44L 3HOXL 3S16L 2WAQP 3HOWL 2E2HL 4A93L 5IP7L 2E2IL 1TWFL 3S17L 5IYDL 2VUML 5C3EL 2B63L 1K83L 3S1RL 2NVYL 4C3HL 5M3ML 3S2DL 3PO2L 3GTOL 2R93L 1TWCL 3GTLL 4C3IL 4A3LL 2NVTL 5IP9L 2JA6L 4BBSL 3GTML 2Y0SP 3H0GL 4A3IL 4C2M1 4A3GL 5IYCL 2YU9L 4A3KL 2JA5L 4QIWP 5M5YL 2R7ZL
chains in the Genus database with same CATH superfamily
1RYQA 5IYBL 1IU6A 5M3FL 1LKPA 1SMMA 2BE5D 3HOZL 5EINC 5MGNA 1T9PA 4AR6A 8RXNA 2EY4E 3HOVL 3GTJL 3GTPL 2AYJA 2NVQL 3NFPI 1YV1A 3P8BA 3KYWA 1I3QL 1Y1VL 3WWLA 5MLC3 5H1Sc 5MF6A 1QYBA 2ERJA 3VPBE 3B0AB 1JYBA 3S1QL 4YWMA 2R92L 4AHXA 5C4JL 4LHNA 3HJWB 1RWDA 3MPSA 4GS7D 2XJVA 4Y52L 5DM61 4AI3A 3HOXL 2PVEA 4A93L 2V0FA 1RB9A 4XXBB 5IP7L 1DX8A 1TWFL 4AI2A 5K2ME 2M6PA 3S17L 1IW7D 5GADc 5C3EL 4AI0A 4AI1A 4YWLA 3KYYA 4C3HL 3PO2L 3GTOL 1PFVA 5IP9L 6RXNA 4A3GL 3KYUA 2PSMC 1BFYA 4LHLA 2XJQA 1R0GA 1P7PA 3B08B 5M5XL 2JI3A 2AUSB 2R93L 4A3CL 2JA8L 1NXGA 1BE7A 3S2HL 5MFPA 4G6BA 3H97A 1B2OA 4JAEA 1SFOL 4V196 1R0JA 4BXXL 4A3FL 2M4VA 3HAXC 3M4OL 1S24A 3PO3L 4AHZA 1TWAL 4ME3A 5AN9H 3LWVB 2ERSA 3LWOB 1R0HA 4A3JL 4A3BL 4AHWA 4POFA 3LWRB 2J9UB 4WFN1 5M5WL 3QVDA 1TWGL 1T9QA 4U671 3RZDL 3PIO1 2CR8A 2GMGA 1PFWA 3RZTA 4AR4A 3PIP1 4C3JL 1WCML 3H9CA 3H99A 4A3DL 4A3ML 1LKMA 1TWHL 1PFUA 1R9TL 2VL6A 2RDVA 3LWPB 3H9BA 3S16L 1DVBA 4AR5A 3LNLA 5RXNA 2AQCA 1YK5A 4JAGA 2M4YA 3J7Z1 1B13A 3FDJA 2MS3A 2O5JD 1H7VA 2NYDA 3S1RL 1LKOA 3PZAA 1TWCL 1QCVA 2JI2A 3MQKB 2NVTL 2A6HD 2JA6L 3GTML 3A44A 4A3IL 2PPTA 2YU9L 2V3BB 4A3KL 3PKIA 4C3IL 4AR3A 4BY1L 1IROA 1B2JA 3PL5A 4K9FA 3RYGA 3P2AA 3RZ6A 4ZN1B 1S2ZA 1WJVA 1YUZA 3IU3I 5IY0A 3FKIL 3GTKL 1S30A 4B8CD 4E6YA 5FJ8L 5JVH1 4BBRL 2L0ZA 3HOUL 3LWQB 2XJUA 3I4NL 4Y7NL 3SS2A 1IRNA 4TVMA 1QQTA 5AI2A 1F4LA 1I50L 3HOYL 3WWNB 2WB1P 1Y1WL 1VZGA 4AHYA 5FLML 2A69D 1ZRPA 2XJRA 4POGA 3H3VM 2H12A 1B71A 2XJPA 5MFZA 4AYBP 2HR5A 3S14L 2C6BA 2CKAA 2PMZP 5C44L 1CADA 4TPUA 4UY81 3HOWL 2KN9A 1E8JA 2K2DA 3PWFA 2PYAA 1YUXA 2E2IL 2XJTA 3KYXA 1BQ8A 4ZN3B 1SMUA 2B63L 1K83L 3QQCE 5M3ML 3S2DL 1BRFA 3GTLL 3J7Y1 1RDGA 1ODHA 2Y0SP 3H0GL 1LTLA 5AI3A 3PKJA 1R0IA 2JA5L 4QIWP 5M5YL 2M6OA 1NNQA 3S15L 3M3YL 5DM71 1VZIA 3I4ML 3CQZL 2NVXL 2HVYC 1IU5A 2ZIXA 4JAFA 2B5ID 1FHHA 2PVXA 2E2JL 4BY7L 1PFYA 1YK4A 3ZG6A 3RZOL 1NXEA 1SMWA 2A68D 3KYVA 3GTQL 4X6AL 1C09A 2V0EA 2JI1A 1R0FA 3JR7A 2Z3QB 3S1NL 2RFKB 3GTGL 5GAEc 3HKZP 3K35A 2JA7L 1OWBA 2XJSA 2C6AA 4XGHA 1RDVA 1I6HL 1FHMA 1BQ9A 3K7AL 2CKCA 1VCXA 5C4XL 4JADA 3S1ML 2DSXA 5GAGc 1VZHA 5EIOC 4A3EL 1RYTA 3LPEB 2QL0A 2A6ED 5JVG1 2WAQP 1T9OA 2E2HL 1OWCA 2KKDA 1PZXA 5IYDL 2VUML 3HJYB 1CAAA 2NVYL 2Z3RB 5GAHc 2LCQA 7RXNA 4A3LL 3MSUA 2APOB 4BBSL 4C2M1 5IYCL 4RXNA 1Z92B 2R7ZL
chains in the Genus database with same CATH topology
4A3CL 2JA8L 4BY1L 5IYBL 3S15L 3M3YL 3S2HL 5M3FL 5M5XL 3HOZL 1SFOL 3FKIL 3GTKL 4BXXL 4A3FL 3I4ML 3M4OL 3CQZL 2NVXL 5FJ8L 3PO3L 4BY7L 3HOVL 2E2JL 3GTJL 4BBRL 1TWAL 3HOUL 3GTPL 3I4NL 3RZOL 4Y7NL 2NVQL 4A3JL 3GTQL 4A3BL 4X6AL 1I3QL 5M5WL 1Y1VL 1TWGL 1I50L 3HOYL 3RZDL 3S1NL 2WB1P 1Y1WL 3GTGL 2JA7L 3HKZP 4C3JL 3S1QL 1WCML 5FLML 2R92L 1I6HL 3H3VM 5C4JL 4A3DL 4A3ML 3K7AL 4AYBP 5C4XL 1TWHL 3S1ML 1R9TL 4A3EL 3S14L 2PMZP 4Y52L 5C44L 3HOXL 3S16L 2WAQP 3HOWL 2E2HL 4A93L 5IP7L 2E2IL 1TWFL 3S17L 5IYDL 2VUML 5C3EL 2B63L 1K83L 3S1RL 2NVYL 4C3HL 5M3ML 3S2DL 3PO2L 3GTOL 2R93L 1TWCL 3GTLL 4C3IL 4A3LL 2NVTL 5IP9L 2JA6L 4BBSL 3GTML 2Y0SP 3H0GL 4A3IL 4C2M1 4A3GL 5IYCL 2YU9L 4A3KL 2JA5L 4QIWP 5M5YL 2R7ZL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3C L;  2JA8 L;  4BY1 L;  5IYB L;  3S15 L;  3M3Y L;  3S2H L;  5M3F L;  5M5X L;  3HOZ L;  1SFO L;  3FKI L;  3GTK L;  4BXX L;  4A3F L;  3I4M L;  3M4O L;  3CQZ L;  2NVX L;  5FJ8 L;  3PO3 L;  4BY7 L;  3HOV L;  2E2J L;  3GTJ L;  4BBR L;  1TWA L;  3HOU L;  3GTP L;  3I4N L;  3RZO L;  4Y7N L;  2NVQ L;  4A3J L;  3GTQ L;  4A3B L;  4X6A L;  1I3Q L;  5M5W L;  1Y1V L;  1TWG L;  1I50 L;  3HOY L;  3RZD L;  3S1N L;  2WB1 P;  1Y1W L;  3GTG L;  2JA7 L;  3HKZ P;  4C3J L;  3S1Q L;  1WCM L;  5FLM L;  2R92 L;  1I6H L;  3H3V M;  5C4J L;  4A3D L;  4A3M L;  3K7A L;  4AYB P;  5C4X L;  1TWH L;  3S1M L;  1R9T L;  4A3E L;  3S14 L;  2PMZ P;  4Y52 L;  5C44 L;  3HOX L;  3S16 L;  2WAQ P;  3HOW L;  2E2H L;  4A93 L;  5IP7 L;  2E2I L;  1TWF L;  3S17 L;  5IYD L;  2VUM L;  5C3E L;  2B63 L;  1K83 L;  3S1R L;  2NVY L;  4C3H L;  5M3M L;  3S2D L;  3PO2 L;  3GTO L;  2R93 L;  1TWC L;  3GTL L;  4C3I L;  4A3L L;  2NVT L;  5IP9 L;  2JA6 L;  4BBS L;  3GTM L;  2Y0S P;  3H0G L;  4A3I L;  4C2M 1;  4A3G L;  5IYC L;  2YU9 L;  4A3K L;  2JA5 L;  4QIW P;  5M5Y L;  2R7Z L; 
#chains in the Genus database with same CATH topology
 1RYQ A;  5IYB L;  1IU6 A;  5M3F L;  1LKP A;  1SMM A;  2BE5 D;  3HOZ L;  5EIN C;  5MGN A;  1T9P A;  4AR6 A;  8RXN A;  2EY4 E;  3HOV L;  3GTJ L;  3GTP L;  2AYJ A;  2NVQ L;  3NFP I;  1YV1 A;  3P8B A;  3KYW A;  1I3Q L;  1Y1V L;  3WWL A;  5MLC 3;  5H1S c;  5MF6 A;  1QYB A;  2ERJ A;  3VPB E;  3B0A B;  1JYB A;  3S1Q L;  4YWM A;  2R92 L;  4AHX A;  5C4J L;  4LHN A;  3HJW B;  1RWD A;  3MPS A;  4GS7 D;  2XJV A;  4Y52 L;  5DM6 1;  4AI3 A;  3HOX L;  2PVE A;  4A93 L;  2V0F A;  1RB9 A;  4XXB B;  5IP7 L;  1DX8 A;  1TWF L;  4AI2 A;  5K2M E;  2M6P A;  3S17 L;  1IW7 D;  5GAD c;  5C3E L;  4AI0 A;  4AI1 A;  4YWL A;  3KYY A;  4C3H L;  3PO2 L;  3GTO L;  1PFV A;  5IP9 L;  6RXN A;  4A3G L;  3KYU A;  2PSM C;  1BFY A;  4LHL A;  2XJQ A;  1R0G A;  1P7P A;  3B08 B;  5M5X L;  2JI3 A;  2AUS B;  2R93 L;  4A3C L;  2JA8 L;  1NXG A;  1BE7 A;  3S2H L;  5MFP A;  4G6B A;  3H97 A;  1B2O A;  4JAE A;  1SFO L;  4V19 6;  1R0J A;  4BXX L;  4A3F L;  2M4V A;  3HAX C;  3M4O L;  1S24 A;  3PO3 L;  4AHZ A;  1TWA L;  4ME3 A;  5AN9 H;  3LWV B;  2ERS A;  3LWO B;  1R0H A;  4A3J L;  4A3B L;  4AHW A;  4POF A;  3LWR B;  2J9U B;  4WFN 1;  5M5W L;  3QVD A;  1TWG L;  1T9Q A;  4U67 1;  3RZD L;  3PIO 1;  2CR8 A;  2GMG A;  1PFW A;  3RZT A;  4AR4 A;  3PIP 1;  4C3J L;  1WCM L;  3H9C A;  3H99 A;  4A3D L;  4A3M L;  1LKM A;  1TWH L;  1PFU A;  1R9T L;  2VL6 A;  2RDV A;  3LWP B;  3H9B A;  3S16 L;  1DVB A;  4AR5 A;  3LNL A;  5RXN A;  2AQC A;  1YK5 A;  4JAG A;  2M4Y A;  3J7Z 1;  1B13 A;  3FDJ A;  2MS3 A;  2O5J D;  1H7V A;  2NYD A;  3S1R L;  1LKO A;  3PZA A;  1TWC L;  1QCV A;  2JI2 A;  3MQK B;  2NVT L;  2A6H D;  2JA6 L;  3GTM L;  3A44 A;  4A3I L;  2PPT A;  2YU9 L;  2V3B B;  4A3K L;  3PKI A;  4C3I L;  4AR3 A;  4BY1 L;  1IRO A;  1B2J A;  3PL5 A;  4K9F A;  3RYG A;  3P2A A;  3RZ6 A;  4ZN1 B;  1S2Z A;  1WJV A;  1YUZ A;  3IU3 I;  5IY0 A;  3FKI L;  3GTK L;  1S30 A;  4B8C D;  4E6Y A;  5FJ8 L;  5JVH 1;  4BBR L;  2L0Z A;  3HOU L;  3LWQ B;  2XJU A;  3I4N L;  4Y7N L;  3SS2 A;  1IRN A;  4TVM A;  1QQT A;  5AI2 A;  1F4L A;  1I50 L;  3HOY L;  3WWN B;  2WB1 P;  1Y1W L;  1VZG A;  4AHY A;  5FLM L;  2A69 D;  1ZRP A;  2XJR A;  4POG A;  3H3V M;  2H12 A;  1B71 A;  2XJP A;  5MFZ A;  4AYB P;  2HR5 A;  3S14 L;  2C6B A;  2CKA A;  2PMZ P;  5C44 L;  1CAD A;  4TPU A;  4UY8 1;  3HOW L;  2KN9 A;  1E8J A;  2K2D A;  3PWF A;  2PYA A;  1YUX A;  2E2I L;  2XJT A;  3KYX A;  1BQ8 A;  4ZN3 B;  1SMU A;  2B63 L;  1K83 L;  3QQC E;  5M3M L;  3S2D L;  1BRF A;  3GTL L;  3J7Y 1;  1RDG A;  1ODH A;  2Y0S P;  3H0G L;  1LTL A;  5AI3 A;  3PKJ A;  1R0I A;  2JA5 L;  4QIW P;  5M5Y L;  2M6O A;  1NNQ A;  3S15 L;  3M3Y L;  5DM7 1;  1VZI A;  3I4M L;  3CQZ L;  2NVX L;  2HVY C;  1IU5 A;  2ZIX A;  4JAF A;  2B5I D;  1FHH A;  2PVX A;  2E2J L;  4BY7 L;  1PFY A;  1YK4 A;  3ZG6 A;  3RZO L;  1NXE A;  1SMW A;  2A68 D;  3KYV A;  3GTQ L;  4X6A L;  1C09 A;  2V0E A;  2JI1 A;  1R0F A;  3JR7 A;  2Z3Q B;  3S1N L;  2RFK B;  3GTG L;  5GAE c;  3HKZ P;  3K35 A;  2JA7 L;  1OWB A;  2XJS A;  2C6A A;  4XGH A;  1RDV A;  1I6H L;  1FHM A;  1BQ9 A;  3K7A L;  2CKC A;  1VCX A;  5C4X L;  4JAD A;  3S1M L;  2DSX A;  5GAG c;  1VZH A;  5EIO C;  4A3E L;  1RYT A;  3LPE B;  2QL0 A;  2A6E D;  5JVG 1;  2WAQ P;  1T9O A;  2E2H L;  1OWC A;  2KKD A;  1PZX A;  5IYD L;  2VUM L;  3HJY B;  1CAA A;  2NVY L;  2Z3R B;  5GAH c;  2LCQ A;  7RXN A;  4A3L L;  3MSU A;  2APO B;  4BBS L;  4C2M 1;  5IYC L;  4RXN A;  1Z92 B;  2R7Z L; 
#chains in the Genus database with same CATH homology
 4A3C L;  2JA8 L;  4BY1 L;  5IYB L;  3S15 L;  3M3Y L;  3S2H L;  5M3F L;  5M5X L;  3HOZ L;  1SFO L;  3FKI L;  3GTK L;  4BXX L;  4A3F L;  3I4M L;  3M4O L;  3CQZ L;  2NVX L;  5FJ8 L;  3PO3 L;  4BY7 L;  3HOV L;  2E2J L;  3GTJ L;  4BBR L;  1TWA L;  3HOU L;  3GTP L;  3I4N L;  3RZO L;  4Y7N L;  2NVQ L;  4A3J L;  3GTQ L;  4A3B L;  4X6A L;  1I3Q L;  5M5W L;  1Y1V L;  1TWG L;  1I50 L;  3HOY L;  3RZD L;  3S1N L;  2WB1 P;  1Y1W L;  3GTG L;  2JA7 L;  3HKZ P;  4C3J L;  3S1Q L;  1WCM L;  5FLM L;  2R92 L;  1I6H L;  3H3V M;  5C4J L;  4A3D L;  4A3M L;  3K7A L;  4AYB P;  5C4X L;  1TWH L;  3S1M L;  1R9T L;  4A3E L;  3S14 L;  2PMZ P;  4Y52 L;  5C44 L;  3HOX L;  3S16 L;  2WAQ P;  3HOW L;  2E2H L;  4A93 L;  5IP7 L;  2E2I L;  1TWF L;  3S17 L;  5IYD L;  2VUM L;  5C3E L;  2B63 L;  1K83 L;  3S1R L;  2NVY L;  4C3H L;  5M3M L;  3S2D L;  3PO2 L;  3GTO L;  2R93 L;  1TWC L;  3GTL L;  4C3I L;  4A3L L;  2NVT L;  5IP9 L;  2JA6 L;  4BBS L;  3GTM L;  2Y0S P;  3H0G L;  4A3I L;  4C2M 1;  4A3G L;  5IYC L;  2YU9 L;  4A3K L;  2JA5 L;  4QIW P;  5M5Y L;  2R7Z L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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