2QJCA

Crystal structure of a putative diadenosine tetraphosphatase
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
242
structure length
222
Chain Sequence
YANVVTLPNVTGRVIIVGDIHGCRAQLEDLLRAVSFKQGSDTLVAVGDLVNKGPDSFGVVRLLKRLGAYSVLGNHDAKLLKLVKKLSLAPLAQSIPTDVETYLSQLPHIIRIPAHNVMVAHAGLHPQRPVDRQYEDEVTTMRNLIEKVTLTATEETNDGGKPWASMWRGPETVVFGHDARRGLQEQYKPLAIGLDSRCVYGGRLSAAVFPGGCIISVPGWNG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural genomics of protein phosphatases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma brucei
molecule keywords Diadenosine tetraphosphatase, putative
total genus 63
structure length 222
sequence length 242
ec nomenclature ec 3.6.1.41: Bis(5'-nucleosyl)-tetraphosphatase (symmetrical).
pdb deposition date 2007-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2qjcA00
2IE4C 3EGHA 4WWLA 1UTEA 2O8GA 5JPFA 1XM7A 4NZVA 3LL8A 4H2GA 2Q8UA 5EQVA 1OIDA 4V0XA 1S3NA 2Z06A 2Z72A 3IB8A 1II7A 4H1YP 4I5LC 2KKNA 3H68A 3ZTVA 2CV9A 3PSNA 3IVEA 4JA9A 3H63A 1T71A 4B2OA 4MOYA 2IE3C 4TUIA 1WAO1 2XMOA 4FBWA 1OIEA 5J28A 2P6BA 2BCDA 4IYPC 3H62B 4KBPA 1QHWA 2BDXA 3TGHA 2QFPA 3GVEA 4DT2A 4MOVA 2HY1A 4LACC 4XPNA 4ZVZA 3PSOA 1Z2XA 1TCOA 2NXFA 3HVQA 2WDDA 2IAEC 1XZWA 1SU1A 3T1IA 4G9JA 1Z2WA 2Z1AA 3THNA 3FGAC 1M63A 5F3WA 4UT2A 4M0VA 1S3MA 4V0WA 4H2IA 1W24A 1U32A 3QFKA 1KBPA 3RQZA 5B8IA 2JOGA 5C1VA 1WARA 3K7VC 2NPPC 1S3LA 4TUGA 2DFJA 2BQ8X 4FBKA 3AUZA 4JA7A 3AV0A 4KKZA 3KBPA 2NYLC 1QFCA 4H2FA 4O43A 3H69A 4ORAA 3ZU0A 2QJCA 3N5UA 2WDEA 3P71C 4DHLA 4H2BA 4V0VA 1HP1A 2HYOA 3H60A 3H61A 5DNYA 3IVDA 4FBQA 2HYPA 1S70A 3DW8C 4F0ZA 1V73A 3DSDA 1HO5A 1OI8A 1G5BA 4YKEA 1MF8A 3QG5C 3RL5A 4HD0A 3IB7A 1S95A 1JK7A 3JYFA 3THOB 4LTYA 3V4YA 4OR9A 4UT3A 3QFOA 3DSCA 1AUIA 3E7AA 3H67A 3QFNA 4ORBA 4ORCA 4DSYA 2ZBMA 4I5NC 1FJMA 2GJUA 1UF3A 2QFRA 3QFMA 3K7WC 2R17A 3C9FA 4UWQA 1IT6A 2WDCA 5INBA 2AHDA 2YVTA 2NYMC 3H64A 4H1SA 4Q7FA 4O4KA 5JJTA 3CK2A 2WDFA 3EGGA 1NNWA 3C5WC 4LU9A 3H66A 3ICFA 4J6OA 4O5GA 4O24A 5GTUA 1S8EA 4ZX2A 3RL4A 2A22A 2USHA 5IOHA 5JPEA 5HPEA 3E7BA 1HPUA 2O8AA 4FCXA 4IL1A 3RL3A 1T70A 4MP0A 1USHA 4UT3B
chains in the Genus database with same CATH superfamily
2IE4C 3EGHA 4WWLA 1UTEA 2O8GA 2ZOAA 5JPFA 1XM7A 4NZVA 3LL8A 3D03A 2Q8UA 4H2GA 5EQVA 1OIDA 4V0XA 1S3NA 2Z06A 2Z72A 3IB8A 1II7A 4H1YP 4I5LC 2KKNA 3H68A 3ZTVA 2CV9A 3PSNA 3IVEA 4JA9A 3H63A 1T71A 4B2OA 4MOYA 2IE3C 4TUIA 1WAO1 2XMOA 4FBWA 1OIEA 5J28A 2P6BA 2BCDA 4IYPC 3H62B 4KBPA 1QHWA 2BDXA 3TGHA 2QFPA 3GVEA 4DT2A 4MOVA 2HY1A 4LACC 4XPNA 4ZVZA 3PSOA 1Z2XA 1TCOA 2NXFA 3HVQA 2WDDA 2IAEC 1XZWA 1SU1A 3T1IA 4G9JA 1Z2WA 2Z1AA 3THNA 3FGAC 1M63A 5F3WA 4UT2A 4M0VA 1S3MA 4V0WA 4H2IA 1W24A 1U32A 3QFKA 1KBPA 3RQZA 5B8IA 2JOGA 5C1VA 2ZO9B 1WARA 3K7VC 2NPPC 1S3LA 4TUGA 2DFJA 2BQ8X 4FBKA 3AUZA 4JA7A 3AV0A 4KKZA 3KBPA 2NYLC 1QFCA 4H2FA 3FLOA 3H69A 4O43A 4ORAA 2QJCA 3N5UA 2WDEA 3P71C 3ZU0A 4H2BA 4V0VA 4DHLA 1HP1A 2HYOA 3H60A 3H61A 5DNYA 3IVDA 4FBQA 2HYPA 1S70A 3DW8C 4F0ZA 1V73A 3DSDA 1HO5A 1OI8A 1G5BA 4YKEA 1MF8A 3QG5C 3RL5A 4HD0A 3IB7A 1S95A 1JK7A 3JYFA 3THOB 4LTYA 3V4YA 4OR9A 4UT3A 3QFOA 3DSCA 1AUIA 3E7AA 3H67A 3QFNA 4ORBA 4ORCA 4DSYA 2ZBMA 4I5NC 1FJMA 2GJUA 1UF3A 2QFRA 3QFMA 3K7WC 2R17A 3C9FA 4UWQA 1IT6A 2WDCA 5INBA 2AHDA 2YVTA 2NYMC 3H64A 4H1SA 4Q7FA 4O4KA 5JJTA 3CK2A 2WDFA 3EGGA 1NNWA 3C5WC 4LU9A 3H66A 3ICFA 3E0JA 2DXNA 4J6OA 4O5GA 4O24A 5GTUA 1S8EA 4ZX2A 3RL4A 2A22A 2USHA 2YEQA 5IOHA 5JPEA 5HPEA 3E7BA 1HPUA 2O8AA 4FCXA 4IL1A 3RL3A 1T70A 2DXLA 1USHA 4MP0A 4UT3B
chains in the Genus database with same CATH topology
2IE4C 3EGHA 4WWLA 1UTEA 2O8GA 2ZOAA 5JPFA 1XM7A 4NZVA 3LL8A 3D03A 2Q8UA 4H2GA 5EQVA 1OIDA 4V0XA 1S3NA 2Z06A 2Z72A 3IB8A 1II7A 4H1YP 4I5LC 2KKNA 3H68A 3ZTVA 2CV9A 3PSNA 3IVEA 4JA9A 3H63A 1T71A 4B2OA 4MOYA 2IE3C 4TUIA 1WAO1 2XMOA 4FBWA 1OIEA 5J28A 2P6BA 2BCDA 4IYPC 3H62B 4KBPA 1QHWA 2BDXA 3TGHA 2QFPA 3GVEA 4DT2A 4MOVA 2HY1A 4LACC 4XPNA 4ZVZA 3PSOA 1Z2XA 1TCOA 2NXFA 3HVQA 2WDDA 2IAEC 1XZWA 1SU1A 3T1IA 4G9JA 1Z2WA 2Z1AA 3THNA 3FGAC 1M63A 5F3WA 4UT2A 4M0VA 1S3MA 4V0WA 4H2IA 1W24A 1U32A 3QFKA 1KBPA 3RQZA 5B8IA 2JOGA 5C1VA 2ZO9B 1WARA 3K7VC 2NPPC 1S3LA 4TUGA 2DFJA 2BQ8X 4FBKA 3AUZA 4JA7A 3AV0A 4KKZA 3KBPA 2NYLC 1QFCA 4H2FA 3FLOA 3H69A 4O43A 4ORAA 2QJCA 3N5UA 2WDEA 3P71C 3ZU0A 4H2BA 4V0VA 4DHLA 1HP1A 2HYOA 3H60A 3H61A 5DNYA 3IVDA 4FBQA 2HYPA 1S70A 3DW8C 4F0ZA 1V73A 3DSDA 1HO5A 1OI8A 1G5BA 4YKEA 1MF8A 3QG5C 3RL5A 4HD0A 3IB7A 1S95A 1JK7A 3JYFA 3THOB 4LTYA 3V4YA 4OR9A 4UT3A 3QFOA 3DSCA 1AUIA 3E7AA 3H67A 3QFNA 4ORBA 4ORCA 4DSYA 2ZBMA 4I5NC 1FJMA 2GJUA 1UF3A 2QFRA 3QFMA 3K7WC 2R17A 3C9FA 4UWQA 1IT6A 2WDCA 5INBA 2AHDA 2YVTA 2NYMC 3H64A 4H1SA 4Q7FA 4O4KA 5JJTA 3CK2A 2WDFA 3EGGA 1NNWA 3C5WC 4LU9A 3H66A 3ICFA 3E0JA 2DXNA 4J6OA 4O5GA 4O24A 5GTUA 1S8EA 4ZX2A 3RL4A 2A22A 2USHA 2YEQA 5IOHA 5JPEA 5HPEA 3E7BA 1HPUA 2O8AA 4FCXA 4IL1A 3RL3A 1T70A 2DXLA 1USHA 4MP0A 4UT3B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IE4 C;  3EGH A;  4WWL A;  1UTE A;  2O8G A;  5JPF A;  1XM7 A;  4NZV A;  3LL8 A;  4H2G A;  2Q8U A;  5EQV A;  1OID A;  4V0X A;  1S3N A;  2Z06 A;  2Z72 A;  3IB8 A;  1II7 A;  4H1Y P;  4I5L C;  2KKN A;  3H68 A;  3ZTV A;  2CV9 A;  3PSN A;  3IVE A;  4JA9 A;  3H63 A;  1T71 A;  4B2O A;  4MOY A;  2IE3 C;  4TUI A;  1WAO 1;  2XMO A;  4FBW A;  1OIE A;  5J28 A;  2P6B A;  2BCD A;  4IYP C;  3H62 B;  4KBP A;  1QHW A;  2BDX A;  3TGH A;  2QFP A;  3GVE A;  4DT2 A;  4MOV A;  2HY1 A;  4LAC C;  4XPN A;  4ZVZ A;  3PSO A;  1Z2X A;  1TCO A;  2NXF A;  3HVQ A;  2WDD A;  2IAE C;  1XZW A;  1SU1 A;  3T1I A;  4G9J A;  1Z2W A;  2Z1A A;  3THN A;  3FGA C;  1M63 A;  5F3W A;  4UT2 A;  4M0V A;  1S3M A;  4V0W A;  4H2I A;  1W24 A;  1U32 A;  3QFK A;  1KBP A;  3RQZ A;  5B8I A;  2JOG A;  5C1V A;  1WAR A;  3K7V C;  2NPP C;  1S3L A;  4TUG A;  2DFJ A;  2BQ8 X;  4FBK A;  3AUZ A;  4JA7 A;  3AV0 A;  4KKZ A;  3KBP A;  2NYL C;  1QFC A;  4H2F A;  4O43 A;  3H69 A;  4ORA A;  3ZU0 A;  2QJC A;  3N5U A;  2WDE A;  3P71 C;  4DHL A;  4H2B A;  4V0V A;  1HP1 A;  2HYO A;  3H60 A;  3H61 A;  5DNY A;  3IVD A;  4FBQ A;  2HYP A;  1S70 A;  3DW8 C;  4F0Z A;  1V73 A;  3DSD A;  1HO5 A;  1OI8 A;  1G5B A;  4YKE A;  1MF8 A;  3QG5 C;  3RL5 A;  4HD0 A;  3IB7 A;  1S95 A;  1JK7 A;  3JYF A;  3THO B;  4LTY A;  3V4Y A;  4OR9 A;  4UT3 A;  3QFO A;  3DSC A;  1AUI A;  3E7A A;  3H67 A;  3QFN A;  4ORB A;  4ORC A;  4DSY A;  2ZBM A;  4I5N C;  1FJM A;  2GJU A;  1UF3 A;  2QFR A;  3QFM A;  3K7W C;  2R17 A;  3C9F A;  4UWQ A;  1IT6 A;  2WDC A;  5INB A;  2AHD A;  2YVT A;  2NYM C;  3H64 A;  4H1S A;  4Q7F A;  4O4K A;  5JJT A;  3CK2 A;  2WDF A;  3EGG A;  1NNW A;  3C5W C;  4LU9 A;  3H66 A;  3ICF A;  4J6O A;  4O5G A;  4O24 A;  5GTU A;  1S8E A;  4ZX2 A;  3RL4 A;  2A22 A;  2USH A;  5IOH A;  5JPE A;  5HPE A;  3E7B A;  1HPU A;  2O8A A;  4FCX A;  4IL1 A;  3RL3 A;  1T70 A;  4MP0 A;  1USH A;  4UT3 B; 
#chains in the Genus database with same CATH topology
 2IE4 C;  3EGH A;  4WWL A;  1UTE A;  2O8G A;  2ZOA A;  5JPF A;  1XM7 A;  4NZV A;  3LL8 A;  3D03 A;  2Q8U A;  4H2G A;  5EQV A;  1OID A;  4V0X A;  1S3N A;  2Z06 A;  2Z72 A;  3IB8 A;  1II7 A;  4H1Y P;  4I5L C;  2KKN A;  3H68 A;  3ZTV A;  2CV9 A;  3PSN A;  3IVE A;  4JA9 A;  3H63 A;  1T71 A;  4B2O A;  4MOY A;  2IE3 C;  4TUI A;  1WAO 1;  2XMO A;  4FBW A;  1OIE A;  5J28 A;  2P6B A;  2BCD A;  4IYP C;  3H62 B;  4KBP A;  1QHW A;  2BDX A;  3TGH A;  2QFP A;  3GVE A;  4DT2 A;  4MOV A;  2HY1 A;  4LAC C;  4XPN A;  4ZVZ A;  3PSO A;  1Z2X A;  1TCO A;  2NXF A;  3HVQ A;  2WDD A;  2IAE C;  1XZW A;  1SU1 A;  3T1I A;  4G9J A;  1Z2W A;  2Z1A A;  3THN A;  3FGA C;  1M63 A;  5F3W A;  4UT2 A;  4M0V A;  1S3M A;  4V0W A;  4H2I A;  1W24 A;  1U32 A;  3QFK A;  1KBP A;  3RQZ A;  5B8I A;  2JOG A;  5C1V A;  2ZO9 B;  1WAR A;  3K7V C;  2NPP C;  1S3L A;  4TUG A;  2DFJ A;  2BQ8 X;  4FBK A;  3AUZ A;  4JA7 A;  3AV0 A;  4KKZ A;  3KBP A;  2NYL C;  1QFC A;  4H2F A;  3FLO A;  3H69 A;  4O43 A;  4ORA A;  2QJC A;  3N5U A;  2WDE A;  3P71 C;  3ZU0 A;  4H2B A;  4V0V A;  4DHL A;  1HP1 A;  2HYO A;  3H60 A;  3H61 A;  5DNY A;  3IVD A;  4FBQ A;  2HYP A;  1S70 A;  3DW8 C;  4F0Z A;  1V73 A;  3DSD A;  1HO5 A;  1OI8 A;  1G5B A;  4YKE A;  1MF8 A;  3QG5 C;  3RL5 A;  4HD0 A;  3IB7 A;  1S95 A;  1JK7 A;  3JYF A;  3THO B;  4LTY A;  3V4Y A;  4OR9 A;  4UT3 A;  3QFO A;  3DSC A;  1AUI A;  3E7A A;  3H67 A;  3QFN A;  4ORB A;  4ORC A;  4DSY A;  2ZBM A;  4I5N C;  1FJM A;  2GJU A;  1UF3 A;  2QFR A;  3QFM A;  3K7W C;  2R17 A;  3C9F A;  4UWQ A;  1IT6 A;  2WDC A;  5INB A;  2AHD A;  2YVT A;  2NYM C;  3H64 A;  4H1S A;  4Q7F A;  4O4K A;  5JJT A;  3CK2 A;  2WDF A;  3EGG A;  1NNW A;  3C5W C;  4LU9 A;  3H66 A;  3ICF A;  3E0J A;  2DXN A;  4J6O A;  4O5G A;  4O24 A;  5GTU A;  1S8E A;  4ZX2 A;  3RL4 A;  2A22 A;  2USH A;  2YEQ A;  5IOH A;  5JPE A;  5HPE A;  3E7B A;  1HPU A;  2O8A A;  4FCX A;  4IL1 A;  3RL3 A;  1T70 A;  2DXL A;  1USH A;  4MP0 A;  4UT3 B; 
#chains in the Genus database with same CATH homology
 2IE4 C;  3EGH A;  4WWL A;  1UTE A;  2O8G A;  2ZOA A;  5JPF A;  1XM7 A;  4NZV A;  3LL8 A;  3D03 A;  2Q8U A;  4H2G A;  5EQV A;  1OID A;  4V0X A;  1S3N A;  2Z06 A;  2Z72 A;  3IB8 A;  1II7 A;  4H1Y P;  4I5L C;  2KKN A;  3H68 A;  3ZTV A;  2CV9 A;  3PSN A;  3IVE A;  4JA9 A;  3H63 A;  1T71 A;  4B2O A;  4MOY A;  2IE3 C;  4TUI A;  1WAO 1;  2XMO A;  4FBW A;  1OIE A;  5J28 A;  2P6B A;  2BCD A;  4IYP C;  3H62 B;  4KBP A;  1QHW A;  2BDX A;  3TGH A;  2QFP A;  3GVE A;  4DT2 A;  4MOV A;  2HY1 A;  4LAC C;  4XPN A;  4ZVZ A;  3PSO A;  1Z2X A;  1TCO A;  2NXF A;  3HVQ A;  2WDD A;  2IAE C;  1XZW A;  1SU1 A;  3T1I A;  4G9J A;  1Z2W A;  2Z1A A;  3THN A;  3FGA C;  1M63 A;  5F3W A;  4UT2 A;  4M0V A;  1S3M A;  4V0W A;  4H2I A;  1W24 A;  1U32 A;  3QFK A;  1KBP A;  3RQZ A;  5B8I A;  2JOG A;  5C1V A;  2ZO9 B;  1WAR A;  3K7V C;  2NPP C;  1S3L A;  4TUG A;  2DFJ A;  2BQ8 X;  4FBK A;  3AUZ A;  4JA7 A;  3AV0 A;  4KKZ A;  3KBP A;  2NYL C;  1QFC A;  4H2F A;  3FLO A;  3H69 A;  4O43 A;  4ORA A;  2QJC A;  3N5U A;  2WDE A;  3P71 C;  3ZU0 A;  4H2B A;  4V0V A;  4DHL A;  1HP1 A;  2HYO A;  3H60 A;  3H61 A;  5DNY A;  3IVD A;  4FBQ A;  2HYP A;  1S70 A;  3DW8 C;  4F0Z A;  1V73 A;  3DSD A;  1HO5 A;  1OI8 A;  1G5B A;  4YKE A;  1MF8 A;  3QG5 C;  3RL5 A;  4HD0 A;  3IB7 A;  1S95 A;  1JK7 A;  3JYF A;  3THO B;  4LTY A;  3V4Y A;  4OR9 A;  4UT3 A;  3QFO A;  3DSC A;  1AUI A;  3E7A A;  3H67 A;  3QFN A;  4ORB A;  4ORC A;  4DSY A;  2ZBM A;  4I5N C;  1FJM A;  2GJU A;  1UF3 A;  2QFR A;  3QFM A;  3K7W C;  2R17 A;  3C9F A;  4UWQ A;  1IT6 A;  2WDC A;  5INB A;  2AHD A;  2YVT A;  2NYM C;  3H64 A;  4H1S A;  4Q7F A;  4O4K A;  5JJT A;  3CK2 A;  2WDF A;  3EGG A;  1NNW A;  3C5W C;  4LU9 A;  3H66 A;  3ICF A;  3E0J A;  2DXN A;  4J6O A;  4O5G A;  4O24 A;  5GTU A;  1S8E A;  4ZX2 A;  3RL4 A;  2A22 A;  2USH A;  2YEQ A;  5IOH A;  5JPE A;  5HPE A;  3E7B A;  1HPU A;  2O8A A;  4FCX A;  4IL1 A;  3RL3 A;  1T70 A;  2DXL A;  1USH A;  4MP0 A;  4UT3 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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