2V0FA

Brk domain from human chd7
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
87
structure length
87
Chain Sequence
GSRNPNKLDINTLTGEERVPVVNKRNGKKMGGAMAPPMKDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVRGEGAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structure of the Brk Domains from Chd7
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7
total genus 14
structure length 87
sequence length 87
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2007-05-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07533 BRK BRK domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.130 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2v0fA01
2V0FA 2CKCA 2CKAA 2V0EA
chains in the Genus database with same CATH superfamily
3J7Z1 2Y0SP 1YK5A 2A6HD 3S16L 2CR8A 5MGNA 3RZ6A 1PFUA 4BY1L 3S2DL 4BY7L 5H1Sc 2O5JD 5M3FL 2K2DA 1CAAA 3RYGA 4V196 1S24A 5IP9L 4AR4A 1I3QL 5EIOC 5MF6A 1DX8A 1LKMA 1LKPA 4XGHA 1B2JA 2L0ZA 3K35A 2Z3QB 3S15L 3S1QL 1VZIA 1T9PA 5M5YL 1S2ZA 1R0HA 3VPBE 8RXNA 3S2HL 3I4NL 5JVG1 3KYVA 3PWFA 4A3ML 5K2ME 3KYYA 1F4LA 4A3IL 1FHHA 2C6AA 2RFKB 2ZIXA 1I6HL 1IROA 4BXXL 4B8CD 4K9FA 1B13A 5M3ML 2A68D 2J9UB 1SMWA 7RXNA 5GAGc 3CQZL 4A3BL 4LHLA 5AI3A 2JI2A 3M4OL 1TWCL 3HAXC 1RB9A 4C2M1 2PSMC 4A3LL 2KKDA 2XJQA 4QIWP 4POGA 3NFPI 2QL0A 4AI2A 4A3GL 4JAEA 1SMUA 3GTPL 2HR5A 3H3VM 1Z92B 4A3KL 5JVH1 3HJYB 2ERSA 4TPUA 3GTOL 2A6ED 1B71A 3KYWA 4U671 5IY0A 1SFOL 1VZGA 1T9QA 1ODHA 1QQTA 3HOYL 5AI2A 3HOWL 3H9BA 3LWQB 3RZDL 1ZRPA 2DSXA 5AN9H 3PZAA 2C6BA 4RXNA 4XXBB 1K83L 4ZN1B 2JA8L 5GAEc 4AHYA 3GTQL 2M6PA 2JI1A 2RDVA 3K7AL 3QQCE 2PPTA 4BBSL 4AR3A 4A93L 3IU3I 3MQKB 5C44L 1IRNA 1IU5A 3PIP1 4E6YA 5IYDL 3FDJA 3P2AA 2VUML 5MFPA 3M3YL 1NXGA 1R9TL 2NVXL 1R0GA 2WAQP 3HOVL 1YUZA 3HOXL 4C3HL 2PVXA 2CKCA 2CKAA 4POFA 2R93L 2AYJA 1Y1VL 1OWBA 3H99A 3S1NL 1RYTA 4AYBP 2E2IL 2GMGA 4Y7NL 5C4JL 1S30A 5EINC 1JYBA 2XJSA 3PO2L 4JADA 3MPSA 2XJVA 5M5WL 5MFZA 1LTLA 3LWRB 2VL6A 3KYUA 4Y52L 2B5ID 3GTLL 3GTJL 1RWDA 3LWOB 2AQCA 1Y1WL 5M5XL 4A3EL 2NVYL 2WB1P 2PYAA 2BE5D 1PFVA 1PZXA 3RZTA 5FJ8L 3LNLA 3MSUA 4ZN3B 4ME3A 3GTKL 3ZG6A 2ERJA 1FHMA 1R0IA 1TWGL 3QVDA 1TWFL 1QCVA 4BBRL 5MLC3 1WJVA 5IP7L 1BE7A 2PVEA 3RZOL 2MS3A 2PMZP 2NVQL 1VZHA 1YV1A 2Z3RB 1BRFA 1RYQA 1E8JA 4A3CL 3A44A 5FLML 3KYXA 4YWMA 2NYDA 2XJRA 2YU9L 3S17L 3LWVB 2JA6L 4JAFA 5DM71 2H12A 2HVYC 1LKOA 1P7PA 4AR6A 2B63L 4AI3A 1CADA 2XJUA 3LWPB 1OWCA 4LHNA 1BQ9A 4WFN1 1I50L 1QYBA 5IYCL 2XJPA 1TWAL 1R0FA 1T9OA 2APOB 2JA5L 1IW7D 1SMMA 1YUXA 4AHZA 1NXEA 3P8BA 2LCQA 1NNQA 1YK4A 1WCML 4GS7D 5C4XL 1PFYA 3HKZP 1C09A 2XJTA 1R0JA 1H7VA 2NVTL 3B0AB 5GAHc 3S14L 1B2OA 3S1ML 1TWHL 4A3JL 1IU6A 3PKIA 4G6BA 2M4YA 5C3EL 3HJWB 3JR7A 2EY4E 1BQ8A 4JAGA 2V3BB 2A69D 2JI3A 3HOZL 4AI1A 3GTGL 1BFYA 2JA7L 4A3FL 1RDGA 1RDVA 5GADc 3WWLA 3GTML 4AHWA 2R92L 4C3JL 3H0GL 1PFWA 3SS2A 6RXNA 3J7Y1 4A3DL 4X6AL 1VCXA 4YWLA 5DM61 4TVMA 3I4ML 3PKJA 3LPEB 3FKIL 2M4VA 2E2JL 1DVBA 3PIO1 3HOUL 3H97A 5IYBL 4C3IL 2M6OA 4AR5A 3WWNB 4AHXA 2V0FA 3B08B 3H9CA 3PL5A 2E2HL 4UY81 5RXNA 3PO3L 3S1RL 2KN9A 2AUSB 2R7ZL 2V0EA 4AI0A
chains in the Genus database with same CATH topology
2HR5A 5MFZA 3J7Z1 2XJPA 1S30A 1Z92B 1YK5A 4AHZA 2A6HD 2CR8A 1R0FA 1T9OA 5MGNA 5JVH1 5EINC 3RZ6A 1JYBA 1IW7D 2XJSA 4JADA 3MPSA 5H1Sc 1SMMA 2ERSA 1YUXA 2XJVA 2O5JD 1NXEA 2K2DA 3P8BA 1LTLA 2A6ED 1B71A 1CAAA 1NNQA 1YK4A 4TPUA 2LCQA 3RYGA 4GS7D 4V196 1S24A 2VL6A 3KYWA 3KYUA 2B5ID 4U671 4AR4A 5IY0A 1RWDA 1C09A 1VZGA 1T9QA 5EIOC 5MF6A 1ODHA 2XJTA 1R0JA 1DX8A 1H7VA 3B0AB 5GAHc 1LKMA 1LKPA 1B2OA 4XGHA 1B2JA 5AI2A 2L0ZA 3K35A 2Z3QB 1IU6A 1ZRPA 3PKIA 2M4YA 2DSXA 4G6BA 5AN9H 3PZAA 2PYAA 1VZIA 2BE5D 1BQ8A 4JAGA 3RZTA 2V3BB 1T9PA 2C6BA 2A69D 2JI3A 1S2ZA 4AI1A 3LNLA 1R0HA 3MSUA 3VPBE 4ME3A 4ZN3B 8RXNA 1BFYA 4RXNA 4XXBB 3ZG6A 5JVG1 1RDGA 2ERJA 3KYVA 3PWFA 4ZN1B 5GAEc 1RDVA 5GADc 4AHYA 5K2ME 2M6PA 1FHMA 3WWLA 1R0IA 2JI1A 3KYYA 2RDVA 3QQCE 4AHWA 3QVDA 2PPTA 1QCVA 4AR3A 1FHHA 3SS2A 6RXNA 1WJVA 2C6AA 3IU3I 5MLC3 3J7Y1 1BE7A 2PVEA 2ZIXA 1VCXA 1IROA 2MS3A 4YWLA 4B8CD 1IRNA 5DM61 1IU5A 4K9FA 3PIP1 4E6YA 4TVMA 1B13A 2A68D 3P2AA 3PKJA 1VZHA 1YV1A 2J9UB 1SMWA 2Z3RB 7RXNA 3LPEB 1BRFA 1RYQA 2M4VA 5MFPA 1E8JA 5GAGc 1DVBA 3A44A 1NXGA 3PIO1 4LHLA 5AI3A 1R0GA 2JI2A 3KYXA 4YWMA 2NYDA 2M6OA 1YUZA 2XJRA 4AR5A 3WWNB 2PVXA 2CKCA 2CKAA 4POFA 4AHXA 2V0FA 2AYJA 4AI0A 4JAFA 3B08B 4UY81 5DM71 2H12A 5RXNA 1LKOA 1OWBA 1RB9A 4AR6A 4AI3A 1CADA 2XJUA 1RYTA 2KN9A 2PSMC 1OWCA 4LHNA 2KKDA 2XJQA 4POGA 2GMGA 1BQ9A 4WFN1 2V0EA 1QYBA 3NFPI 2QL0A 4AI2A 4JAEA 1SMUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V0F A;  2CKC A;  2CKA A;  2V0E A; 
#chains in the Genus database with same CATH topology
 3J7Z 1;  2Y0S P;  1YK5 A;  2A6H D;  3S16 L;  2CR8 A;  5MGN A;  3RZ6 A;  1PFU A;  4BY1 L;  3S2D L;  4BY7 L;  5H1S c;  2O5J D;  5M3F L;  2K2D A;  1CAA A;  3RYG A;  4V19 6;  1S24 A;  5IP9 L;  4AR4 A;  1I3Q L;  5EIO C;  5MF6 A;  1DX8 A;  1LKM A;  1LKP A;  4XGH A;  1B2J A;  2L0Z A;  3K35 A;  2Z3Q B;  3S15 L;  3S1Q L;  1VZI A;  1T9P A;  5M5Y L;  1S2Z A;  1R0H A;  3VPB E;  8RXN A;  3S2H L;  3I4N L;  5JVG 1;  3KYV A;  3PWF A;  4A3M L;  5K2M E;  3KYY A;  1F4L A;  4A3I L;  1FHH A;  2C6A A;  2RFK B;  2ZIX A;  1I6H L;  1IRO A;  4BXX L;  4B8C D;  4K9F A;  1B13 A;  5M3M L;  2A68 D;  2J9U B;  1SMW A;  7RXN A;  5GAG c;  3CQZ L;  4A3B L;  4LHL A;  5AI3 A;  2JI2 A;  3M4O L;  1TWC L;  3HAX C;  1RB9 A;  4C2M 1;  2PSM C;  4A3L L;  2KKD A;  2XJQ A;  4QIW P;  4POG A;  3NFP I;  2QL0 A;  4AI2 A;  4A3G L;  4JAE A;  1SMU A;  3GTP L;  2HR5 A;  3H3V M;  1Z92 B;  4A3K L;  5JVH 1;  3HJY B;  2ERS A;  4TPU A;  3GTO L;  2A6E D;  1B71 A;  3KYW A;  4U67 1;  5IY0 A;  1SFO L;  1VZG A;  1T9Q A;  1ODH A;  1QQT A;  3HOY L;  5AI2 A;  3HOW L;  3H9B A;  3LWQ B;  3RZD L;  1ZRP A;  2DSX A;  5AN9 H;  3PZA A;  2C6B A;  4RXN A;  4XXB B;  1K83 L;  4ZN1 B;  2JA8 L;  5GAE c;  4AHY A;  3GTQ L;  2M6P A;  2JI1 A;  2RDV A;  3K7A L;  3QQC E;  2PPT A;  4BBS L;  4AR3 A;  4A93 L;  3IU3 I;  3MQK B;  5C44 L;  1IRN A;  1IU5 A;  3PIP 1;  4E6Y A;  5IYD L;  3FDJ A;  3P2A A;  2VUM L;  5MFP A;  3M3Y L;  1NXG A;  1R9T L;  2NVX L;  1R0G A;  2WAQ P;  3HOV L;  1YUZ A;  3HOX L;  4C3H L;  2PVX A;  2CKC A;  2CKA A;  4POF A;  2R93 L;  2AYJ A;  1Y1V L;  1OWB A;  3H99 A;  3S1N L;  1RYT A;  4AYB P;  2E2I L;  2GMG A;  4Y7N L;  5C4J L;  1S30 A;  5EIN C;  1JYB A;  2XJS A;  3PO2 L;  4JAD A;  3MPS A;  2XJV A;  5M5W L;  5MFZ A;  1LTL A;  3LWR B;  2VL6 A;  3KYU A;  4Y52 L;  2B5I D;  3GTL L;  3GTJ L;  1RWD A;  3LWO B;  2AQC A;  1Y1W L;  5M5X L;  4A3E L;  2NVY L;  2WB1 P;  2PYA A;  2BE5 D;  1PFV A;  1PZX A;  3RZT A;  5FJ8 L;  3LNL A;  3MSU A;  4ZN3 B;  4ME3 A;  3GTK L;  3ZG6 A;  2ERJ A;  1FHM A;  1R0I A;  1TWG L;  3QVD A;  1TWF L;  1QCV A;  4BBR L;  5MLC 3;  1WJV A;  5IP7 L;  1BE7 A;  2PVE A;  3RZO L;  2MS3 A;  2PMZ P;  2NVQ L;  1VZH A;  1YV1 A;  2Z3R B;  1BRF A;  1RYQ A;  1E8J A;  4A3C L;  3A44 A;  5FLM L;  3KYX A;  4YWM A;  2NYD A;  2XJR A;  2YU9 L;  3S17 L;  3LWV B;  2JA6 L;  4JAF A;  5DM7 1;  2H12 A;  2HVY C;  1LKO A;  1P7P A;  4AR6 A;  2B63 L;  4AI3 A;  1CAD A;  2XJU A;  3LWP B;  1OWC A;  4LHN A;  1BQ9 A;  4WFN 1;  1I50 L;  1QYB A;  5IYC L;  2XJP A;  1TWA L;  1R0F A;  1T9O A;  2APO B;  2JA5 L;  1IW7 D;  1SMM A;  1YUX A;  4AHZ A;  1NXE A;  3P8B A;  2LCQ A;  1NNQ A;  1YK4 A;  1WCM L;  4GS7 D;  5C4X L;  1PFY A;  3HKZ P;  1C09 A;  2XJT A;  1R0J A;  1H7V A;  2NVT L;  3B0A B;  5GAH c;  3S14 L;  1B2O A;  3S1M L;  1TWH L;  4A3J L;  1IU6 A;  3PKI A;  4G6B A;  2M4Y A;  5C3E L;  3HJW B;  3JR7 A;  2EY4 E;  1BQ8 A;  4JAG A;  2V3B B;  2A69 D;  2JI3 A;  3HOZ L;  4AI1 A;  3GTG L;  1BFY A;  2JA7 L;  4A3F L;  1RDG A;  1RDV A;  5GAD c;  3WWL A;  3GTM L;  4AHW A;  2R92 L;  4C3J L;  3H0G L;  1PFW A;  3SS2 A;  6RXN A;  3J7Y 1;  4A3D L;  4X6A L;  1VCX A;  4YWL A;  5DM6 1;  4TVM A;  3I4M L;  3PKJ A;  3LPE B;  3FKI L;  2M4V A;  2E2J L;  1DVB A;  3PIO 1;  3HOU L;  3H97 A;  5IYB L;  4C3I L;  2M6O A;  4AR5 A;  3WWN B;  4AHX A;  2V0F A;  3B08 B;  3H9C A;  3PL5 A;  2E2H L;  4UY8 1;  5RXN A;  3PO3 L;  3S1R L;  2KN9 A;  2AUS B;  2R7Z L;  2V0E A;  4AI0 A; 
#chains in the Genus database with same CATH homology
 2HR5 A;  5MFZ A;  3J7Z 1;  2XJP A;  1S30 A;  1Z92 B;  1YK5 A;  4AHZ A;  2A6H D;  2CR8 A;  1R0F A;  1T9O A;  5MGN A;  5JVH 1;  5EIN C;  3RZ6 A;  1JYB A;  1IW7 D;  2XJS A;  4JAD A;  3MPS A;  5H1S c;  1SMM A;  2ERS A;  1YUX A;  2XJV A;  2O5J D;  1NXE A;  2K2D A;  3P8B A;  1LTL A;  2A6E D;  1B71 A;  1CAA A;  1NNQ A;  1YK4 A;  4TPU A;  2LCQ A;  3RYG A;  4GS7 D;  4V19 6;  1S24 A;  2VL6 A;  3KYW A;  3KYU A;  2B5I D;  4U67 1;  4AR4 A;  5IY0 A;  1RWD A;  1C09 A;  1VZG A;  1T9Q A;  5EIO C;  5MF6 A;  1ODH A;  2XJT A;  1R0J A;  1DX8 A;  1H7V A;  3B0A B;  5GAH c;  1LKM A;  1LKP A;  1B2O A;  4XGH A;  1B2J A;  5AI2 A;  2L0Z A;  3K35 A;  2Z3Q B;  1IU6 A;  1ZRP A;  3PKI A;  2M4Y A;  2DSX A;  4G6B A;  5AN9 H;  3PZA A;  2PYA A;  1VZI A;  2BE5 D;  1BQ8 A;  4JAG A;  3RZT A;  2V3B B;  1T9P A;  2C6B A;  2A69 D;  2JI3 A;  1S2Z A;  4AI1 A;  3LNL A;  1R0H A;  3MSU A;  3VPB E;  4ME3 A;  4ZN3 B;  8RXN A;  1BFY A;  4RXN A;  4XXB B;  3ZG6 A;  5JVG 1;  1RDG A;  2ERJ A;  3KYV A;  3PWF A;  4ZN1 B;  5GAE c;  1RDV A;  5GAD c;  4AHY A;  5K2M E;  2M6P A;  1FHM A;  3WWL A;  1R0I A;  2JI1 A;  3KYY A;  2RDV A;  3QQC E;  4AHW A;  3QVD A;  2PPT A;  1QCV A;  4AR3 A;  1FHH A;  3SS2 A;  6RXN A;  1WJV A;  2C6A A;  3IU3 I;  5MLC 3;  3J7Y 1;  1BE7 A;  2PVE A;  2ZIX A;  1VCX A;  1IRO A;  2MS3 A;  4YWL A;  4B8C D;  1IRN A;  5DM6 1;  1IU5 A;  4K9F A;  3PIP 1;  4E6Y A;  4TVM A;  1B13 A;  2A68 D;  3P2A A;  3PKJ A;  1VZH A;  1YV1 A;  2J9U B;  1SMW A;  2Z3R B;  7RXN A;  3LPE B;  1BRF A;  1RYQ A;  2M4V A;  5MFP A;  1E8J A;  5GAG c;  1DVB A;  3A44 A;  1NXG A;  3PIO 1;  4LHL A;  5AI3 A;  1R0G A;  2JI2 A;  3KYX A;  4YWM A;  2NYD A;  2M6O A;  1YUZ A;  2XJR A;  4AR5 A;  3WWN B;  2PVX A;  2CKC A;  2CKA A;  4POF A;  4AHX A;  2V0F A;  2AYJ A;  4AI0 A;  4JAF A;  3B08 B;  4UY8 1;  5DM7 1;  2H12 A;  5RXN A;  1LKO A;  1OWB A;  1RB9 A;  4AR6 A;  4AI3 A;  1CAD A;  2XJU A;  1RYT A;  2KN9 A;  2PSM C;  1OWC A;  4LHN A;  2KKD A;  2XJQ A;  4POG A;  2GMG A;  1BQ9 A;  4WFN 1;  2V0E A;  1QYB A;  3NFP I;  2QL0 A;  4AI2 A;  4JAE A;  1SMU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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