2YU9L

Rna polymerase ii elongation complex in 150 mm mg+2 with utp
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2007-04-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 2yu9L00
1SFOL 3HOUL 4C3JL 3GTKL 2B63L 1TWGL 4AYBP 2NVQL 5M5YL 3CQZL 3FKIL 2WAQP 2NVYL 2R7ZL 1Y1VL 4Y7NL 3GTLL 3S17L 4X6AL 5FJ8L 5IP7L 2NVXL 2R93L 3S14L 3PO2L 5M3FL 4A3CL 4A3ML 5IYBL 4C2M1 4A3LL 3S16L 2Y0SP 5M5WL 3HKZP 4BY7L 2R92L 3S15L 5C44L 1Y1WL 1TWFL 4BXXL 3GTJL 2WB1P 5C3EL 4A3KL 2NVTL 4A3DL 4BY1L 3GTGL 2JA8L 3S1RL 3PO3L 3H3VM 3HOXL 3M3YL 5IP9L 3S1ML 1I6HL 2JA5L 3M4OL 1I3QL 3GTPL 3HOVL 4Y52L 4BBRL 5M5XL 2JA7L 2VUML 4A93L 3S1NL 1WCML 4A3BL 2E2IL 4C3IL 4QIWP 2JA6L 2E2HL 3I4ML 5M3ML 1R9TL 1I50L 4A3FL 2PMZP 1TWCL 1TWHL 3S2HL 3GTML 3HOWL 5IYCL 4C3HL 5IYDL 5C4JL 4A3JL 5C4XL 4A3GL 3H0GL 5FLML 3I4NL 3K7AL 3GTQL 3RZDL 4A3IL 2E2JL 3HOYL 3GTOL 3S2DL 2YU9L 1K83L 3RZOL 1TWAL 3S1QL 3HOZL 4BBSL 4A3EL
chains in the Genus database with same CATH superfamily
6RXNA 2CR8A 5GADc 1R0JA 3H99A 1PZXA 1VZIA 1R0FA 1NXEA 1Y1VL 3PKJA 3GTLL 3S17L 4X6AL 2XJSA 5FJ8L 4UY81 3KYYA 2GMGA 5IYBL 1PFVA 2XJPA 3HKZP 2MS3A 5DM61 3S15L 4U671 5C44L 1Y1WL 4V196 4BXXL 3GTJL 2C6BA 2Z3RB 2B5ID 1DX8A 3GTGL 3H3VM 1QQTA 3JR7A 3HOXL 1SMMA 2QL0A 5JVG1 1I6HL 1BQ8A 3LWPB 2RFKB 3H9BA 4Y52L 1T9OA 2JA7L 2VUML 3LPEB 1PFUA 1WCML 2HVYC 4C3IL 4QIWP 1LKMA 2JA6L 2A6ED 3VPBE 5M3ML 4A3FL 2PMZP 3S2HL 3GTML 3ZG6A 3KYVA 5C4XL 4A3GL 8RXNA 2C6AA 3I4NL 4A3IL 4ZN3B 3GTOL 5GAHc 3RZOL 3WWLA 5AI2A 3S1QL 5MGNA 4BBSL 2PPTA 3PKIA 1SFOL 3HOUL 2RDVA 1H7VA 2APOB 3GTKL 1VZGA 3LWQB 2NVQL 5M5YL 3FKIL 2WAQP 2NVYL 2R7ZL 4AR4A 5JVH1 5IP7L 2NVXL 2R93L 1FHMA 3S14L 5M3FL 2JI2A 2AYJA 2HR5A 2CKAA 3S16L 2NYDA 1YK5A 4WFN1 3PIO1 2V0EA 2J9UB 4LHNA 3KYXA 5DM71 1NNQA 4JAGA 5C3EL 2V0FA 3HJYB 1LKPA 2O5JD 3PO3L 1WJVA 1B71A 5IP9L 3S1ML 4AR3A 1SMWA 1S2ZA 5M5XL 4B8CD 1YUXA 4ME3A 1SMUA 3J7Y1 2E2IL 2K2DA 1BFYA 1T9QA 1Z92B 3K35A 4LHLA 5GAEc 3I4ML 2AUSB 1I50L 2ERJA 2JI3A 2ERSA 1IU5A 4AI0A 5K2ME 1FHHA 4AR5A 4YWMA 4AHXA 3H0GL 4AI3A 5H1Sc 3K7AL 1LKOA 4K9FA 2M4VA 4POGA 5MFPA 3HAXC 1K83L 2PVXA 1YV1A 2Z3QB 1S30A 7RXNA 1RWDA 4A3EL 4XGHA 4C3JL 1B13A 1CAAA 1TWGL 2CKCA 3CQZL 3RZTA 4JAFA 2ZIXA 1C09A 4RXNA 4AR6A 1S24A 2DSXA 4YWLA 2L0ZA 5MLC3 5MFZA 4E6YA 1B2JA 1ODHA 3LWOB 3B0AB 1OWBA 2V3BB 4C2M1 4A3LL 3PIP1 1IRNA 4BY7L 2VL6A 3J7Z1 1RYQA 3MPSA 1RYTA 2NVTL 1E8JA 3QQCE 3P8BA 3KYWA 5GAGc 1PFYA 4ZN1B 2XJRA 1B2OA 1I3QL 2AQCA 3M4OL 3GTPL 3HOVL 3P2AA 4A93L 3S1NL 1PFWA 4A3BL 3B08B 4TVMA 2PYAA 3FDJA 3HJWB 1R9TL 2LCQA 1QCVA 1TWCL 2EY4E 1BE7A 2XJVA 3HOWL 5IYCL 3KYUA 3A44A 1LTLA 5IYDL 4XXBB 4A3JL 1RB9A 3GTQL 1BQ9A 2A69D 2E2JL 3HOYL 5EINC 4GS7D 1ZRPA 1YUZA 3LWVB 3H9CA 1R0IA 4JADA 2A6HD 1QYBA 1RDGA 1NXGA 2M6OA 1IU6A 2B63L 4AYBP 2KN9A 3RYGA 1BRFA 1IW7D 4Y7NL 1DVBA 2KKDA 1VCXA 2XJTA 1YK4A 1RDVA 1OWCA 3PO2L 3LWRB 4A3CL 1R0HA 4A3ML 1T9PA 3MSUA 2Y0SP 3PL5A 5M5WL 5EIOC 3LNLA 2R92L 1TWFL 3NFPI 3WWNB 1P7PA 2WB1P 4JAEA 2JI1A 1VZHA 2M6PA 4A3KL 4A3DL 4BY1L 2PSMC 2JA8L 3S1RL 3PWFA 3M3YL 1IROA 1CADA 2BE5D 3IU3I 4POFA 2JA5L 3RZ6A 2PVEA 4BBRL 4AI2A 3SS2A 3QVDA 5AN9H 1JYBA 2E2HL 2XJUA 2M4YA 1TWHL 3H97A 2H12A 4AI1A 5AI3A 4TPUA 4C3HL 4G6BA 4AHZA 5C4JL 1R0GA 4AHWA 5FLML 4AHYA 2A68D 3RZDL 3MQKB 3PZAA 1F4LA 2XJQA 5IY0A 5RXNA 3S2DL 2YU9L 1TWAL 3HOZL 5MF6A
chains in the Genus database with same CATH topology
1SFOL 3HOUL 4C3JL 3GTKL 2B63L 1TWGL 4AYBP 2NVQL 5M5YL 3CQZL 3FKIL 2WAQP 2NVYL 2R7ZL 1Y1VL 4Y7NL 3GTLL 3S17L 4X6AL 5FJ8L 5IP7L 2NVXL 2R93L 3S14L 3PO2L 5M3FL 4A3CL 4A3ML 5IYBL 4C2M1 4A3LL 3S16L 2Y0SP 5M5WL 3HKZP 4BY7L 2R92L 3S15L 5C44L 1Y1WL 1TWFL 4BXXL 3GTJL 2WB1P 5C3EL 4A3KL 2NVTL 4A3DL 4BY1L 3GTGL 2JA8L 3S1RL 3PO3L 3H3VM 3HOXL 3M3YL 5IP9L 3S1ML 1I6HL 2JA5L 3M4OL 1I3QL 3GTPL 3HOVL 4Y52L 4BBRL 5M5XL 2JA7L 2VUML 4A93L 3S1NL 1WCML 4A3BL 2E2IL 4C3IL 4QIWP 2JA6L 2E2HL 3I4ML 5M3ML 1R9TL 1I50L 4A3FL 2PMZP 1TWCL 1TWHL 3S2HL 3GTML 3HOWL 5IYCL 4C3HL 5IYDL 5C4JL 4A3JL 5C4XL 4A3GL 3H0GL 5FLML 3I4NL 3K7AL 3GTQL 3RZDL 4A3IL 2E2JL 3HOYL 3GTOL 3S2DL 2YU9L 1K83L 3RZOL 1TWAL 3S1QL 3HOZL 4BBSL 4A3EL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SFO L;  3HOU L;  4C3J L;  3GTK L;  2B63 L;  1TWG L;  4AYB P;  2NVQ L;  5M5Y L;  3CQZ L;  3FKI L;  2WAQ P;  2NVY L;  2R7Z L;  1Y1V L;  4Y7N L;  3GTL L;  3S17 L;  4X6A L;  5FJ8 L;  5IP7 L;  2NVX L;  2R93 L;  3S14 L;  3PO2 L;  5M3F L;  4A3C L;  4A3M L;  5IYB L;  4C2M 1;  4A3L L;  3S16 L;  2Y0S P;  5M5W L;  3HKZ P;  4BY7 L;  2R92 L;  3S15 L;  5C44 L;  1Y1W L;  1TWF L;  4BXX L;  3GTJ L;  2WB1 P;  5C3E L;  4A3K L;  2NVT L;  4A3D L;  4BY1 L;  3GTG L;  2JA8 L;  3S1R L;  3PO3 L;  3H3V M;  3HOX L;  3M3Y L;  5IP9 L;  3S1M L;  1I6H L;  2JA5 L;  3M4O L;  1I3Q L;  3GTP L;  3HOV L;  4Y52 L;  4BBR L;  5M5X L;  2JA7 L;  2VUM L;  4A93 L;  3S1N L;  1WCM L;  4A3B L;  2E2I L;  4C3I L;  4QIW P;  2JA6 L;  2E2H L;  3I4M L;  5M3M L;  1R9T L;  1I50 L;  4A3F L;  2PMZ P;  1TWC L;  1TWH L;  3S2H L;  3GTM L;  3HOW L;  5IYC L;  4C3H L;  5IYD L;  5C4J L;  4A3J L;  5C4X L;  4A3G L;  3H0G L;  5FLM L;  3I4N L;  3K7A L;  3GTQ L;  3RZD L;  4A3I L;  2E2J L;  3HOY L;  3GTO L;  3S2D L;  2YU9 L;  1K83 L;  3RZO L;  1TWA L;  3S1Q L;  3HOZ L;  4BBS L;  4A3E L; 
#chains in the Genus database with same CATH topology
 6RXN A;  2CR8 A;  5GAD c;  1R0J A;  3H99 A;  1PZX A;  1VZI A;  1R0F A;  1NXE A;  1Y1V L;  3PKJ A;  3GTL L;  3S17 L;  4X6A L;  2XJS A;  5FJ8 L;  4UY8 1;  3KYY A;  2GMG A;  5IYB L;  1PFV A;  2XJP A;  3HKZ P;  2MS3 A;  5DM6 1;  3S15 L;  4U67 1;  5C44 L;  1Y1W L;  4V19 6;  4BXX L;  3GTJ L;  2C6B A;  2Z3R B;  2B5I D;  1DX8 A;  3GTG L;  3H3V M;  1QQT A;  3JR7 A;  3HOX L;  1SMM A;  2QL0 A;  5JVG 1;  1I6H L;  1BQ8 A;  3LWP B;  2RFK B;  3H9B A;  4Y52 L;  1T9O A;  2JA7 L;  2VUM L;  3LPE B;  1PFU A;  1WCM L;  2HVY C;  4C3I L;  4QIW P;  1LKM A;  2JA6 L;  2A6E D;  3VPB E;  5M3M L;  4A3F L;  2PMZ P;  3S2H L;  3GTM L;  3ZG6 A;  3KYV A;  5C4X L;  4A3G L;  8RXN A;  2C6A A;  3I4N L;  4A3I L;  4ZN3 B;  3GTO L;  5GAH c;  3RZO L;  3WWL A;  5AI2 A;  3S1Q L;  5MGN A;  4BBS L;  2PPT A;  3PKI A;  1SFO L;  3HOU L;  2RDV A;  1H7V A;  2APO B;  3GTK L;  1VZG A;  3LWQ B;  2NVQ L;  5M5Y L;  3FKI L;  2WAQ P;  2NVY L;  2R7Z L;  4AR4 A;  5JVH 1;  5IP7 L;  2NVX L;  2R93 L;  1FHM A;  3S14 L;  5M3F L;  2JI2 A;  2AYJ A;  2HR5 A;  2CKA A;  3S16 L;  2NYD A;  1YK5 A;  4WFN 1;  3PIO 1;  2V0E A;  2J9U B;  4LHN A;  3KYX A;  5DM7 1;  1NNQ A;  4JAG A;  5C3E L;  2V0F A;  3HJY B;  1LKP A;  2O5J D;  3PO3 L;  1WJV A;  1B71 A;  5IP9 L;  3S1M L;  4AR3 A;  1SMW A;  1S2Z A;  5M5X L;  4B8C D;  1YUX A;  4ME3 A;  1SMU A;  3J7Y 1;  2E2I L;  2K2D A;  1BFY A;  1T9Q A;  1Z92 B;  3K35 A;  4LHL A;  5GAE c;  3I4M L;  2AUS B;  1I50 L;  2ERJ A;  2JI3 A;  2ERS A;  1IU5 A;  4AI0 A;  5K2M E;  1FHH A;  4AR5 A;  4YWM A;  4AHX A;  3H0G L;  4AI3 A;  5H1S c;  3K7A L;  1LKO A;  4K9F A;  2M4V A;  4POG A;  5MFP A;  3HAX C;  1K83 L;  2PVX A;  1YV1 A;  2Z3Q B;  1S30 A;  7RXN A;  1RWD A;  4A3E L;  4XGH A;  4C3J L;  1B13 A;  1CAA A;  1TWG L;  2CKC A;  3CQZ L;  3RZT A;  4JAF A;  2ZIX A;  1C09 A;  4RXN A;  4AR6 A;  1S24 A;  2DSX A;  4YWL A;  2L0Z A;  5MLC 3;  5MFZ A;  4E6Y A;  1B2J A;  1ODH A;  3LWO B;  3B0A B;  1OWB A;  2V3B B;  4C2M 1;  4A3L L;  3PIP 1;  1IRN A;  4BY7 L;  2VL6 A;  3J7Z 1;  1RYQ A;  3MPS A;  1RYT A;  2NVT L;  1E8J A;  3QQC E;  3P8B A;  3KYW A;  5GAG c;  1PFY A;  4ZN1 B;  2XJR A;  1B2O A;  1I3Q L;  2AQC A;  3M4O L;  3GTP L;  3HOV L;  3P2A A;  4A93 L;  3S1N L;  1PFW A;  4A3B L;  3B08 B;  4TVM A;  2PYA A;  3FDJ A;  3HJW B;  1R9T L;  2LCQ A;  1QCV A;  1TWC L;  2EY4 E;  1BE7 A;  2XJV A;  3HOW L;  5IYC L;  3KYU A;  3A44 A;  1LTL A;  5IYD L;  4XXB B;  4A3J L;  1RB9 A;  3GTQ L;  1BQ9 A;  2A69 D;  2E2J L;  3HOY L;  5EIN C;  4GS7 D;  1ZRP A;  1YUZ A;  3LWV B;  3H9C A;  1R0I A;  4JAD A;  2A6H D;  1QYB A;  1RDG A;  1NXG A;  2M6O A;  1IU6 A;  2B63 L;  4AYB P;  2KN9 A;  3RYG A;  1BRF A;  1IW7 D;  4Y7N L;  1DVB A;  2KKD A;  1VCX A;  2XJT A;  1YK4 A;  1RDV A;  1OWC A;  3PO2 L;  3LWR B;  4A3C L;  1R0H A;  4A3M L;  1T9P A;  3MSU A;  2Y0S P;  3PL5 A;  5M5W L;  5EIO C;  3LNL A;  2R92 L;  1TWF L;  3NFP I;  3WWN B;  1P7P A;  2WB1 P;  4JAE A;  2JI1 A;  1VZH A;  2M6P A;  4A3K L;  4A3D L;  4BY1 L;  2PSM C;  2JA8 L;  3S1R L;  3PWF A;  3M3Y L;  1IRO A;  1CAD A;  2BE5 D;  3IU3 I;  4POF A;  2JA5 L;  3RZ6 A;  2PVE A;  4BBR L;  4AI2 A;  3SS2 A;  3QVD A;  5AN9 H;  1JYB A;  2E2H L;  2XJU A;  2M4Y A;  1TWH L;  3H97 A;  2H12 A;  4AI1 A;  5AI3 A;  4TPU A;  4C3H L;  4G6B A;  4AHZ A;  5C4J L;  1R0G A;  4AHW A;  5FLM L;  4AHY A;  2A68 D;  3RZD L;  3MQK B;  3PZA A;  1F4L A;  2XJQ A;  5IY0 A;  5RXN A;  3S2D L;  2YU9 L;  1TWA L;  3HOZ L;  5MF6 A; 
#chains in the Genus database with same CATH homology
 1SFO L;  3HOU L;  4C3J L;  3GTK L;  2B63 L;  1TWG L;  4AYB P;  2NVQ L;  5M5Y L;  3CQZ L;  3FKI L;  2WAQ P;  2NVY L;  2R7Z L;  1Y1V L;  4Y7N L;  3GTL L;  3S17 L;  4X6A L;  5FJ8 L;  5IP7 L;  2NVX L;  2R93 L;  3S14 L;  3PO2 L;  5M3F L;  4A3C L;  4A3M L;  5IYB L;  4C2M 1;  4A3L L;  3S16 L;  2Y0S P;  5M5W L;  3HKZ P;  4BY7 L;  2R92 L;  3S15 L;  5C44 L;  1Y1W L;  1TWF L;  4BXX L;  3GTJ L;  2WB1 P;  5C3E L;  4A3K L;  2NVT L;  4A3D L;  4BY1 L;  3GTG L;  2JA8 L;  3S1R L;  3PO3 L;  3H3V M;  3HOX L;  3M3Y L;  5IP9 L;  3S1M L;  1I6H L;  2JA5 L;  3M4O L;  1I3Q L;  3GTP L;  3HOV L;  4Y52 L;  4BBR L;  5M5X L;  2JA7 L;  2VUM L;  4A93 L;  3S1N L;  1WCM L;  4A3B L;  2E2I L;  4C3I L;  4QIW P;  2JA6 L;  2E2H L;  3I4M L;  5M3M L;  1R9T L;  1I50 L;  4A3F L;  2PMZ P;  1TWC L;  1TWH L;  3S2H L;  3GTM L;  3HOW L;  5IYC L;  4C3H L;  5IYD L;  5C4J L;  4A3J L;  5C4X L;  4A3G L;  3H0G L;  5FLM L;  3I4N L;  3K7A L;  3GTQ L;  3RZD L;  4A3I L;  2E2J L;  3HOY L;  3GTO L;  3S2D L;  2YU9 L;  1K83 L;  3RZO L;  1TWA L;  3S1Q L;  3HOZ L;  4BBS L;  4A3E L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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