2Z72A

New structure of cold-active protein tyrosine phosphatase at 1.1 angstrom
Total Genus 122
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
122
sequence length
338
structure length
338
Chain Sequence
ATEFDGPYVITPISGQSTAYWICDNRLKTTSIEKLQVNRPEHCGDLPETKLSSEIKQIMPDTYLGIKKVVALSDVHGQYDVLLTLLKKQKIIDSDGNWAFGEGHMVMTGDIFDRGHQVNEVLWFMYQLDQQARDAGGMVHLLMGNHEQMVLGGDLRYVHQRYDIATTLINRPYNKLYSADTEIGQWLRSKNTIIKINDVLYMHGGISSEWISRELTLDKANALYRANVDASKKSLKADDLLNFLFFGNGPTWYRGYFSETFTEAELDTILQHFNVNHIVVGHTSQERVLGLFHNKVIAVDSSIKVGKSGELLLLENNRLIRGLYDGTRETLQENSLNQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The role of group bulkiness in the catalytic activity of psychrophile cold-active protein tyrosine phosphatase
pubmed doi rcsb
molecule tags Hydrolase
source organism Shewanella sp.
molecule keywords Protein-tyrosine-phosphatase
total genus 122
structure length 338
sequence length 338
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2z72A00
1JK7A 3RL5A 2IE4C 4LU9A 4FBQA 3QFKA 2HY1A 1HPUA 2AHDA 3P71C 4H2GA 3H64A 5JPEA 1USHA 3E7BA 2YVTA 4JA9A 1IT6A 1S70A 3H67A 4XPNA 2P6BA 2CV9A 4H2BA 4IYPC 3KBPA 5B8IA 3ICFA 4ZVZA 4DT2A 1Z2WA 3GVEA 4B2OA 1S3NA 4F0ZA 4V0VA 1S3LA 1UTEA 4G9JA 5EQVA 1T71A 3T1IA 4O43A 3H62B 4TUGA 2QFPA 2R17A 3IB7A 4MP0A 3ZU0A 2NPPC 1S95A 4UT3A 4DHLA 3K7VC 3C5WC 3DSDA 1AUIA 3QFNA 4I5LC 1KBPA 3DSCA 4Q7FA 2IE3C 1II7A 2NYLC 2O8AA 4ZX2A 1HP1A 1W24A 5IOHA 2WDCA 3IVEA 3QFMA 5F3WA 3H68A 3THOB 1UF3A 1TCOA 3E7AA 3PSOA 4DSYA 3EGHA 1T70A 3H60A 4OR9A 4WWLA 3QFOA 3RQZA 4KKZA 3AUZA 3H63A 2ZBMA 3IVDA 3PSNA 1S8EA 3CK2A 4O4KA 4ORAA 2Z72A 1SU1A 3DW8C 4V0WA 3H66A 2HYOA 1HO5A 3AV0A 4I5NC 1S3MA 4H1SA 4FCXA 3H69A 2Z06A 3EGGA 4NZVA 3ZTVA 4KBPA 2O8GA 1NNWA 3C9FA 1OIDA 3IB8A 3FGAC 4ORCA 4FBKA 4IL1A 1Z2XA 2HYPA 3N5UA 3THNA 4H2FA 3QG5C 5INBA 2QJCA 4MOYA 3K7WC 4V0XA 4UT2A 2WDFA 2Z1AA 2QFRA 2Q8UA 5C1VA 2WDDA 2BCDA 4YKEA 3TGHA 3LL8A 2JOGA 2BQ8X 4H1YP 1WAO1 1QFCA 2NXFA 2XMOA 1U32A 4JA7A 4TUIA 4LTYA 3H61A 3RL3A 2KKNA 2A22A 4UWQA 5J28A 1OI8A 2GJUA 2NYMC 2USHA 4J6OA 4O24A 4HD0A 1QHWA 1FJMA 4O5GA 1WARA 1G5BA 3V4YA 2IAEC 4ORBA 5JPFA 3JYFA 4FBWA 5HPEA 2WDEA 3HVQA 5GTUA 4H2IA 2BDXA 5JJTA 4UT3B 1XM7A 1V73A 4LACC 4MOVA 3RL4A 5DNYA 1MF8A 1XZWA 2DFJA 1M63A 1OIEA 4M0VA
chains in the Genus database with same CATH superfamily
1JK7A 3RL5A 2IE4C 4LU9A 4FBQA 3QFKA 2HY1A 1HPUA 2AHDA 3P71C 4H2GA 3H64A 5JPEA 1USHA 3E7BA 2YVTA 4JA9A 1IT6A 1S70A 3H67A 4XPNA 2P6BA 2CV9A 4H2BA 4IYPC 2DXLA 3KBPA 5B8IA 3ICFA 4ZVZA 4DT2A 1Z2WA 3GVEA 4B2OA 1S3NA 4F0ZA 4V0VA 1S3LA 1UTEA 4G9JA 5EQVA 1T71A 3T1IA 4O43A 3H62B 4TUGA 2QFPA 2R17A 3IB7A 4MP0A 3ZU0A 2NPPC 1S95A 2ZOAA 4UT3A 4DHLA 3K7VC 3C5WC 3DSDA 1AUIA 3QFNA 4I5LC 1KBPA 3DSCA 4Q7FA 2IE3C 1II7A 2NYLC 2O8AA 4ZX2A 1HP1A 1W24A 5IOHA 2WDCA 3IVEA 3QFMA 5F3WA 3H68A 3FLOA 3THOB 1UF3A 2YEQA 1TCOA 3E7AA 3PSOA 4DSYA 3EGHA 1T70A 3H60A 4OR9A 4WWLA 3QFOA 3RQZA 4KKZA 3AUZA 3H63A 2ZBMA 3IVDA 3PSNA 1S8EA 3CK2A 4O4KA 4ORAA 2Z72A 1SU1A 3DW8C 4V0WA 3H66A 2HYOA 1HO5A 3AV0A 4I5NC 1S3MA 4H1SA 4FCXA 3H69A 2Z06A 3EGGA 4NZVA 3ZTVA 4KBPA 2O8GA 1NNWA 3C9FA 1OIDA 3IB8A 3FGAC 4ORCA 4FBKA 4IL1A 1Z2XA 2HYPA 3N5UA 3THNA 4H2FA 3QG5C 5INBA 2QJCA 4MOYA 3K7WC 4V0XA 2DXNA 2WDFA 4UT2A 3E0JA 2Z1AA 2QFRA 3D03A 2Q8UA 5C1VA 2WDDA 2BCDA 4YKEA 3TGHA 3LL8A 2JOGA 2BQ8X 4H1YP 1WAO1 1QFCA 2NXFA 2XMOA 1U32A 4JA7A 4TUIA 4LTYA 3H61A 3RL3A 2ZO9B 2KKNA 2A22A 4UWQA 5J28A 1OI8A 2GJUA 2NYMC 2USHA 4J6OA 4O24A 4HD0A 1QHWA 1FJMA 4O5GA 1WARA 1G5BA 3V4YA 2IAEC 4ORBA 5JPFA 3JYFA 4FBWA 5HPEA 2WDEA 3HVQA 5GTUA 4H2IA 2BDXA 5JJTA 4UT3B 1XM7A 1V73A 4LACC 4MOVA 3RL4A 5DNYA 1MF8A 1XZWA 2DFJA 1M63A 1OIEA 4M0VA
chains in the Genus database with same CATH topology
1JK7A 3RL5A 2IE4C 4LU9A 4FBQA 3QFKA 2HY1A 1HPUA 2AHDA 3P71C 4H2GA 3H64A 5JPEA 1USHA 3E7BA 2YVTA 4JA9A 1IT6A 1S70A 3H67A 4XPNA 2P6BA 2CV9A 4H2BA 4IYPC 2DXLA 3KBPA 5B8IA 3ICFA 4ZVZA 4DT2A 1Z2WA 3GVEA 4B2OA 1S3NA 4F0ZA 4V0VA 1S3LA 1UTEA 4G9JA 5EQVA 1T71A 3T1IA 4O43A 3H62B 4TUGA 2QFPA 2R17A 3IB7A 4MP0A 3ZU0A 2NPPC 1S95A 2ZOAA 4UT3A 4DHLA 3K7VC 3C5WC 3DSDA 1AUIA 3QFNA 4I5LC 1KBPA 3DSCA 4Q7FA 2IE3C 1II7A 2NYLC 2O8AA 4ZX2A 1HP1A 1W24A 5IOHA 2WDCA 3IVEA 3QFMA 5F3WA 3H68A 3FLOA 3THOB 1UF3A 2YEQA 1TCOA 3E7AA 3PSOA 4DSYA 3EGHA 1T70A 3H60A 4OR9A 4WWLA 3QFOA 3RQZA 4KKZA 3AUZA 3H63A 2ZBMA 3IVDA 3PSNA 1S8EA 3CK2A 4O4KA 4ORAA 2Z72A 1SU1A 3DW8C 4V0WA 3H66A 2HYOA 1HO5A 3AV0A 4I5NC 1S3MA 4H1SA 4FCXA 3H69A 2Z06A 3EGGA 4NZVA 3ZTVA 4KBPA 2O8GA 1NNWA 3C9FA 1OIDA 3IB8A 3FGAC 4ORCA 4FBKA 4IL1A 1Z2XA 2HYPA 3N5UA 3THNA 4H2FA 3QG5C 5INBA 2QJCA 4MOYA 3K7WC 4V0XA 2DXNA 2WDFA 4UT2A 3E0JA 2Z1AA 2QFRA 3D03A 2Q8UA 5C1VA 2WDDA 2BCDA 4YKEA 3TGHA 3LL8A 2JOGA 2BQ8X 4H1YP 1WAO1 1QFCA 2NXFA 2XMOA 1U32A 4JA7A 4TUIA 4LTYA 3H61A 3RL3A 2ZO9B 2KKNA 2A22A 4UWQA 5J28A 1OI8A 2GJUA 2NYMC 2USHA 4J6OA 4O24A 4HD0A 1QHWA 1FJMA 4O5GA 1WARA 1G5BA 3V4YA 2IAEC 4ORBA 5JPFA 3JYFA 4FBWA 5HPEA 2WDEA 3HVQA 5GTUA 4H2IA 2BDXA 5JJTA 4UT3B 1XM7A 1V73A 4LACC 4MOVA 3RL4A 5DNYA 1MF8A 1XZWA 2DFJA 1M63A 1OIEA 4M0VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JK7 A;  3RL5 A;  2IE4 C;  4LU9 A;  4FBQ A;  3QFK A;  2HY1 A;  1HPU A;  2AHD A;  3P71 C;  4H2G A;  3H64 A;  5JPE A;  1USH A;  3E7B A;  2YVT A;  4JA9 A;  1IT6 A;  1S70 A;  3H67 A;  4XPN A;  2P6B A;  2CV9 A;  4H2B A;  4IYP C;  3KBP A;  5B8I A;  3ICF A;  4ZVZ A;  4DT2 A;  1Z2W A;  3GVE A;  4B2O A;  1S3N A;  4F0Z A;  4V0V A;  1S3L A;  1UTE A;  4G9J A;  5EQV A;  1T71 A;  3T1I A;  4O43 A;  3H62 B;  4TUG A;  2QFP A;  2R17 A;  3IB7 A;  4MP0 A;  3ZU0 A;  2NPP C;  1S95 A;  4UT3 A;  4DHL A;  3K7V C;  3C5W C;  3DSD A;  1AUI A;  3QFN A;  4I5L C;  1KBP A;  3DSC A;  4Q7F A;  2IE3 C;  1II7 A;  2NYL C;  2O8A A;  4ZX2 A;  1HP1 A;  1W24 A;  5IOH A;  2WDC A;  3IVE A;  3QFM A;  5F3W A;  3H68 A;  3THO B;  1UF3 A;  1TCO A;  3E7A A;  3PSO A;  4DSY A;  3EGH A;  1T70 A;  3H60 A;  4OR9 A;  4WWL A;  3QFO A;  3RQZ A;  4KKZ A;  3AUZ A;  3H63 A;  2ZBM A;  3IVD A;  3PSN A;  1S8E A;  3CK2 A;  4O4K A;  4ORA A;  2Z72 A;  1SU1 A;  3DW8 C;  4V0W A;  3H66 A;  2HYO A;  1HO5 A;  3AV0 A;  4I5N C;  1S3M A;  4H1S A;  4FCX A;  3H69 A;  2Z06 A;  3EGG A;  4NZV A;  3ZTV A;  4KBP A;  2O8G A;  1NNW A;  3C9F A;  1OID A;  3IB8 A;  3FGA C;  4ORC A;  4FBK A;  4IL1 A;  1Z2X A;  2HYP A;  3N5U A;  3THN A;  4H2F A;  3QG5 C;  5INB A;  2QJC A;  4MOY A;  3K7W C;  4V0X A;  4UT2 A;  2WDF A;  2Z1A A;  2QFR A;  2Q8U A;  5C1V A;  2WDD A;  2BCD A;  4YKE A;  3TGH A;  3LL8 A;  2JOG A;  2BQ8 X;  4H1Y P;  1WAO 1;  1QFC A;  2NXF A;  2XMO A;  1U32 A;  4JA7 A;  4TUI A;  4LTY A;  3H61 A;  3RL3 A;  2KKN A;  2A22 A;  4UWQ A;  5J28 A;  1OI8 A;  2GJU A;  2NYM C;  2USH A;  4J6O A;  4O24 A;  4HD0 A;  1QHW A;  1FJM A;  4O5G A;  1WAR A;  1G5B A;  3V4Y A;  2IAE C;  4ORB A;  5JPF A;  3JYF A;  4FBW A;  5HPE A;  2WDE A;  3HVQ A;  5GTU A;  4H2I A;  2BDX A;  5JJT A;  4UT3 B;  1XM7 A;  1V73 A;  4LAC C;  4MOV A;  3RL4 A;  5DNY A;  1MF8 A;  1XZW A;  2DFJ A;  1M63 A;  1OIE A;  4M0V A; 
#chains in the Genus database with same CATH topology
 1JK7 A;  3RL5 A;  2IE4 C;  4LU9 A;  4FBQ A;  3QFK A;  2HY1 A;  1HPU A;  2AHD A;  3P71 C;  4H2G A;  3H64 A;  5JPE A;  1USH A;  3E7B A;  2YVT A;  4JA9 A;  1IT6 A;  1S70 A;  3H67 A;  4XPN A;  2P6B A;  2CV9 A;  4H2B A;  4IYP C;  2DXL A;  3KBP A;  5B8I A;  3ICF A;  4ZVZ A;  4DT2 A;  1Z2W A;  3GVE A;  4B2O A;  1S3N A;  4F0Z A;  4V0V A;  1S3L A;  1UTE A;  4G9J A;  5EQV A;  1T71 A;  3T1I A;  4O43 A;  3H62 B;  4TUG A;  2QFP A;  2R17 A;  3IB7 A;  4MP0 A;  3ZU0 A;  2NPP C;  1S95 A;  2ZOA A;  4UT3 A;  4DHL A;  3K7V C;  3C5W C;  3DSD A;  1AUI A;  3QFN A;  4I5L C;  1KBP A;  3DSC A;  4Q7F A;  2IE3 C;  1II7 A;  2NYL C;  2O8A A;  4ZX2 A;  1HP1 A;  1W24 A;  5IOH A;  2WDC A;  3IVE A;  3QFM A;  5F3W A;  3H68 A;  3FLO A;  3THO B;  1UF3 A;  2YEQ A;  1TCO A;  3E7A A;  3PSO A;  4DSY A;  3EGH A;  1T70 A;  3H60 A;  4OR9 A;  4WWL A;  3QFO A;  3RQZ A;  4KKZ A;  3AUZ A;  3H63 A;  2ZBM A;  3IVD A;  3PSN A;  1S8E A;  3CK2 A;  4O4K A;  4ORA A;  2Z72 A;  1SU1 A;  3DW8 C;  4V0W A;  3H66 A;  2HYO A;  1HO5 A;  3AV0 A;  4I5N C;  1S3M A;  4H1S A;  4FCX A;  3H69 A;  2Z06 A;  3EGG A;  4NZV A;  3ZTV A;  4KBP A;  2O8G A;  1NNW A;  3C9F A;  1OID A;  3IB8 A;  3FGA C;  4ORC A;  4FBK A;  4IL1 A;  1Z2X A;  2HYP A;  3N5U A;  3THN A;  4H2F A;  3QG5 C;  5INB A;  2QJC A;  4MOY A;  3K7W C;  4V0X A;  2DXN A;  2WDF A;  4UT2 A;  3E0J A;  2Z1A A;  2QFR A;  3D03 A;  2Q8U A;  5C1V A;  2WDD A;  2BCD A;  4YKE A;  3TGH A;  3LL8 A;  2JOG A;  2BQ8 X;  4H1Y P;  1WAO 1;  1QFC A;  2NXF A;  2XMO A;  1U32 A;  4JA7 A;  4TUI A;  4LTY A;  3H61 A;  3RL3 A;  2ZO9 B;  2KKN A;  2A22 A;  4UWQ A;  5J28 A;  1OI8 A;  2GJU A;  2NYM C;  2USH A;  4J6O A;  4O24 A;  4HD0 A;  1QHW A;  1FJM A;  4O5G A;  1WAR A;  1G5B A;  3V4Y A;  2IAE C;  4ORB A;  5JPF A;  3JYF A;  4FBW A;  5HPE A;  2WDE A;  3HVQ A;  5GTU A;  4H2I A;  2BDX A;  5JJT A;  4UT3 B;  1XM7 A;  1V73 A;  4LAC C;  4MOV A;  3RL4 A;  5DNY A;  1MF8 A;  1XZW A;  2DFJ A;  1M63 A;  1OIE A;  4M0V A; 
#chains in the Genus database with same CATH homology
 1JK7 A;  3RL5 A;  2IE4 C;  4LU9 A;  4FBQ A;  3QFK A;  2HY1 A;  1HPU A;  2AHD A;  3P71 C;  4H2G A;  3H64 A;  5JPE A;  1USH A;  3E7B A;  2YVT A;  4JA9 A;  1IT6 A;  1S70 A;  3H67 A;  4XPN A;  2P6B A;  2CV9 A;  4H2B A;  4IYP C;  2DXL A;  3KBP A;  5B8I A;  3ICF A;  4ZVZ A;  4DT2 A;  1Z2W A;  3GVE A;  4B2O A;  1S3N A;  4F0Z A;  4V0V A;  1S3L A;  1UTE A;  4G9J A;  5EQV A;  1T71 A;  3T1I A;  4O43 A;  3H62 B;  4TUG A;  2QFP A;  2R17 A;  3IB7 A;  4MP0 A;  3ZU0 A;  2NPP C;  1S95 A;  2ZOA A;  4UT3 A;  4DHL A;  3K7V C;  3C5W C;  3DSD A;  1AUI A;  3QFN A;  4I5L C;  1KBP A;  3DSC A;  4Q7F A;  2IE3 C;  1II7 A;  2NYL C;  2O8A A;  4ZX2 A;  1HP1 A;  1W24 A;  5IOH A;  2WDC A;  3IVE A;  3QFM A;  5F3W A;  3H68 A;  3FLO A;  3THO B;  1UF3 A;  2YEQ A;  1TCO A;  3E7A A;  3PSO A;  4DSY A;  3EGH A;  1T70 A;  3H60 A;  4OR9 A;  4WWL A;  3QFO A;  3RQZ A;  4KKZ A;  3AUZ A;  3H63 A;  2ZBM A;  3IVD A;  3PSN A;  1S8E A;  3CK2 A;  4O4K A;  4ORA A;  2Z72 A;  1SU1 A;  3DW8 C;  4V0W A;  3H66 A;  2HYO A;  1HO5 A;  3AV0 A;  4I5N C;  1S3M A;  4H1S A;  4FCX A;  3H69 A;  2Z06 A;  3EGG A;  4NZV A;  3ZTV A;  4KBP A;  2O8G A;  1NNW A;  3C9F A;  1OID A;  3IB8 A;  3FGA C;  4ORC A;  4FBK A;  4IL1 A;  1Z2X A;  2HYP A;  3N5U A;  3THN A;  4H2F A;  3QG5 C;  5INB A;  2QJC A;  4MOY A;  3K7W C;  4V0X A;  2DXN A;  2WDF A;  4UT2 A;  3E0J A;  2Z1A A;  2QFR A;  3D03 A;  2Q8U A;  5C1V A;  2WDD A;  2BCD A;  4YKE A;  3TGH A;  3LL8 A;  2JOG A;  2BQ8 X;  4H1Y P;  1WAO 1;  1QFC A;  2NXF A;  2XMO A;  1U32 A;  4JA7 A;  4TUI A;  4LTY A;  3H61 A;  3RL3 A;  2ZO9 B;  2KKN A;  2A22 A;  4UWQ A;  5J28 A;  1OI8 A;  2GJU A;  2NYM C;  2USH A;  4J6O A;  4O24 A;  4HD0 A;  1QHW A;  1FJM A;  4O5G A;  1WAR A;  1G5B A;  3V4Y A;  2IAE C;  4ORB A;  5JPF A;  3JYF A;  4FBW A;  5HPE A;  2WDE A;  3HVQ A;  5GTU A;  4H2I A;  2BDX A;  5JJT A;  4UT3 B;  1XM7 A;  1V73 A;  4LAC C;  4MOV A;  3RL4 A;  5DNY A;  1MF8 A;  1XZW A;  2DFJ A;  1M63 A;  1OIE A;  4M0V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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