2ZBMA

Crystal structure of i115m mutant cold-active protein tyrosine phosphatase
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
331
structure length
331
Chain Sequence
TEFDGPYVITPISGQSTAYWICDNRLKTTSIEKLQVNRPEHCGDLPETKLSSEIKQIMPDTYLGIKKVVALSDVHGQYDVLLTLLKKQKIIDSDGNWAFGEGHMVMTGDMFDRGHQVNEVLWFMYQLDQQARDAGGMVHLLMGNHEQMVLGGDLRYVHQRYDIATTLINRPYNKLYGADTEIGQWLRSKNTIIKINDVLYMHGGISSEWISRELTLDKANALYRANVDASKKSLKADDLLNFLFFGNGPTWYRGYFSETFTEAELDTILQHFNVNHIVVGHTSQERVLGLFHNKVIAVDSSIKVGKSGELLLLENNRLIRGLYDGTRETLQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The role of group bulkiness in the catalytic activity of psychrophile cold-active protein tyrosine phosphatase
pubmed doi rcsb
molecule tags Hydrolase
source organism Shewanella sp.
molecule keywords Protein-tyrosine-phosphatase
total genus 116
structure length 331
sequence length 331
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-10-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2zbmA00
3H68A 1HP1A 4UT2A 1II7A 2BDXA 4V0WA 4XPNA 5HPEA 5J28A 2NXFA 4ZVZA 4F0ZA 1Z2XA 3FGAC 1AUIA 4HD0A 4DHLA 3ICFA 4Q7FA 2YVTA 1S95A 3AUZA 3QG5C 2Z06A 4OR9A 4DSYA 1Z2WA 1OIDA 2O8GA 4FBKA 1WARA 4FCXA 5GTUA 4KKZA 2WDDA 2P6BA 3THOB 3CK2A 4O43A 4J6OA 4MP0A 3T1IA 3KBPA 1MF8A 3AV0A 3H69A 3IVDA 4H1SA 5C1VA 2NPPC 4KBPA 4MOVA 2CV9A 2O8AA 1S3NA 1USHA 1XM7A 2NYMC 1FJMA 3RQZA 2IE4C 4V0XA 4I5LC 4UT3B 3E7BA 4DT2A 1UTEA 4O24A 3H63A 4IYPC 4LTYA 4WWLA 1S8EA 4TUIA 2BQ8X 2Z1AA 4G9JA 4NZVA 2GJUA 2DFJA 1S3LA 3PSOA 2HYOA 3C5WC 4FBWA 4JA9A 2USHA 3ZU0A 2JOGA 4ORCA 1S70A 4O5GA 4FBQA 2AHDA 1T70A 3IVEA 2QFPA 3QFKA 3DSCA 3IB8A 2WDEA 2HY1A 3QFNA 1TCOA 4H2IA 4LU9A 3P71C 4H2BA 3DSDA 1T71A 2A22A 2WDCA 4LACC 3K7VC 1IT6A 1KBPA 3EGHA 2KKNA 3N5UA 1V73A 5JPFA 5JJTA 4UWQA 3H60A 2IE3C 2NYLC 4MOYA 2Z72A 3H66A 5F3WA 3PSNA 1OI8A 2QJCA 1HO5A 4ORBA 2WDFA 4M0VA 4O4KA 3THNA 4ZX2A 1QHWA 3GVEA 3LL8A 3K7WC 1QFCA 3E7AA 2Q8UA 1W24A 3H67A 1WAO1 3H62B 2QFRA 3RL5A 2ZBMA 4UT3A 1UF3A 4TUGA 4I5NC 4H2FA 1M63A 3IB7A 4V0VA 3H61A 3DW8C 2IAEC 4IL1A 3EGGA 4ORAA 4JA7A 3RL3A 3JYFA 3ZTVA 1U32A 1NNWA 2XMOA 1XZWA 3HVQA 4YKEA 5EQVA 5JPEA 1OIEA 4H2GA 4H1YP 5B8IA 2R17A 4B2OA 3QFMA 1G5BA 1S3MA 3C9FA 2HYPA 3RL4A 3TGHA 3V4YA 5DNYA 5IOHA 2BCDA 3QFOA 5INBA 1SU1A 1JK7A 1HPUA 3H64A
chains in the Genus database with same CATH superfamily
3H68A 1HP1A 4UT2A 1II7A 2BDXA 4V0WA 4XPNA 5HPEA 5J28A 2NXFA 4ZVZA 4F0ZA 1Z2XA 3FGAC 1AUIA 4HD0A 4DHLA 3ICFA 4Q7FA 2YVTA 1S95A 3AUZA 3QG5C 2Z06A 4OR9A 4DSYA 1Z2WA 1OIDA 2O8GA 4FBKA 1WARA 4FCXA 5GTUA 4KKZA 2ZOAA 2WDDA 2P6BA 3THOB 3CK2A 4O43A 4J6OA 4MP0A 3T1IA 3KBPA 1MF8A 3AV0A 3H69A 3IVDA 4H1SA 5C1VA 2NPPC 4KBPA 4MOVA 2CV9A 2O8AA 1S3NA 1USHA 1XM7A 2NYMC 1FJMA 3RQZA 2IE4C 4V0XA 4I5LC 4UT3B 3E7BA 4DT2A 1UTEA 4O24A 3H63A 4IYPC 4LTYA 4WWLA 1S8EA 4TUIA 2BQ8X 2Z1AA 4G9JA 4NZVA 2GJUA 2DFJA 1S3LA 3PSOA 2HYOA 3C5WC 4FBWA 4JA9A 3FLOA 2USHA 3ZU0A 2JOGA 4ORCA 1S70A 4O5GA 4FBQA 2AHDA 1T70A 3IVEA 2QFPA 3QFKA 3DSCA 3IB8A 2WDEA 2HY1A 3QFNA 1TCOA 4H2IA 4LU9A 3E0JA 3P71C 4H2BA 3DSDA 1T71A 2YEQA 2A22A 2ZO9B 2WDCA 4LACC 3D03A 3K7VC 1IT6A 1KBPA 3EGHA 2KKNA 3N5UA 1V73A 5JPFA 5JJTA 4UWQA 3H60A 2IE3C 2NYLC 4MOYA 2Z72A 3H66A 5F3WA 3PSNA 1OI8A 2QJCA 1HO5A 4ORBA 2WDFA 4M0VA 4O4KA 3THNA 4ZX2A 1QHWA 3GVEA 3LL8A 3K7WC 1QFCA 3E7AA 2Q8UA 1W24A 3H67A 1WAO1 3H62B 2QFRA 2DXLA 3RL5A 2ZBMA 4UT3A 1UF3A 4TUGA 4I5NC 4H2FA 1M63A 3IB7A 4V0VA 3H61A 3DW8C 2IAEC 4IL1A 2DXNA 3EGGA 4ORAA 4JA7A 3RL3A 3JYFA 3ZTVA 1U32A 1NNWA 2XMOA 1XZWA 3HVQA 4YKEA 5EQVA 5JPEA 1OIEA 4H2GA 4H1YP 5B8IA 2R17A 4B2OA 3QFMA 1G5BA 1S3MA 3C9FA 2HYPA 3RL4A 3TGHA 3V4YA 5DNYA 5IOHA 2BCDA 3QFOA 5INBA 1SU1A 1JK7A 1HPUA 3H64A
chains in the Genus database with same CATH topology
3H68A 1HP1A 4UT2A 1II7A 2BDXA 4V0WA 4XPNA 5HPEA 5J28A 2NXFA 4ZVZA 4F0ZA 1Z2XA 3FGAC 1AUIA 4HD0A 4DHLA 3ICFA 4Q7FA 2YVTA 1S95A 3AUZA 3QG5C 2Z06A 4OR9A 4DSYA 1Z2WA 1OIDA 2O8GA 4FBKA 1WARA 4FCXA 5GTUA 4KKZA 2ZOAA 2WDDA 2P6BA 3THOB 3CK2A 4O43A 4J6OA 4MP0A 3T1IA 3KBPA 1MF8A 3AV0A 3H69A 3IVDA 4H1SA 5C1VA 2NPPC 4KBPA 4MOVA 2CV9A 2O8AA 1S3NA 1USHA 1XM7A 2NYMC 1FJMA 3RQZA 2IE4C 4V0XA 4I5LC 4UT3B 3E7BA 4DT2A 1UTEA 4O24A 3H63A 4IYPC 4LTYA 4WWLA 1S8EA 4TUIA 2BQ8X 2Z1AA 4G9JA 4NZVA 2GJUA 2DFJA 1S3LA 3PSOA 2HYOA 3C5WC 4FBWA 4JA9A 3FLOA 2USHA 3ZU0A 2JOGA 4ORCA 1S70A 4O5GA 4FBQA 2AHDA 1T70A 3IVEA 2QFPA 3QFKA 3DSCA 3IB8A 2WDEA 2HY1A 3QFNA 1TCOA 4H2IA 4LU9A 3E0JA 3P71C 4H2BA 3DSDA 1T71A 2YEQA 2A22A 2ZO9B 2WDCA 4LACC 3D03A 3K7VC 1IT6A 1KBPA 3EGHA 2KKNA 3N5UA 1V73A 5JPFA 5JJTA 4UWQA 3H60A 2IE3C 2NYLC 4MOYA 2Z72A 3H66A 5F3WA 3PSNA 1OI8A 2QJCA 1HO5A 4ORBA 2WDFA 4M0VA 4O4KA 3THNA 4ZX2A 1QHWA 3GVEA 3LL8A 3K7WC 1QFCA 3E7AA 2Q8UA 1W24A 3H67A 1WAO1 3H62B 2QFRA 2DXLA 3RL5A 2ZBMA 4UT3A 1UF3A 4TUGA 4I5NC 4H2FA 1M63A 3IB7A 4V0VA 3H61A 3DW8C 2IAEC 4IL1A 2DXNA 3EGGA 4ORAA 4JA7A 3RL3A 3JYFA 3ZTVA 1U32A 1NNWA 2XMOA 1XZWA 3HVQA 4YKEA 5EQVA 5JPEA 1OIEA 4H2GA 4H1YP 5B8IA 2R17A 4B2OA 3QFMA 1G5BA 1S3MA 3C9FA 2HYPA 3RL4A 3TGHA 3V4YA 5DNYA 5IOHA 2BCDA 3QFOA 5INBA 1SU1A 1JK7A 1HPUA 3H64A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H68 A;  1HP1 A;  4UT2 A;  1II7 A;  2BDX A;  4V0W A;  4XPN A;  5HPE A;  5J28 A;  2NXF A;  4ZVZ A;  4F0Z A;  1Z2X A;  3FGA C;  1AUI A;  4HD0 A;  4DHL A;  3ICF A;  4Q7F A;  2YVT A;  1S95 A;  3AUZ A;  3QG5 C;  2Z06 A;  4OR9 A;  4DSY A;  1Z2W A;  1OID A;  2O8G A;  4FBK A;  1WAR A;  4FCX A;  5GTU A;  4KKZ A;  2WDD A;  2P6B A;  3THO B;  3CK2 A;  4O43 A;  4J6O A;  4MP0 A;  3T1I A;  3KBP A;  1MF8 A;  3AV0 A;  3H69 A;  3IVD A;  4H1S A;  5C1V A;  2NPP C;  4KBP A;  4MOV A;  2CV9 A;  2O8A A;  1S3N A;  1USH A;  1XM7 A;  2NYM C;  1FJM A;  3RQZ A;  2IE4 C;  4V0X A;  4I5L C;  4UT3 B;  3E7B A;  4DT2 A;  1UTE A;  4O24 A;  3H63 A;  4IYP C;  4LTY A;  4WWL A;  1S8E A;  4TUI A;  2BQ8 X;  2Z1A A;  4G9J A;  4NZV A;  2GJU A;  2DFJ A;  1S3L A;  3PSO A;  2HYO A;  3C5W C;  4FBW A;  4JA9 A;  2USH A;  3ZU0 A;  2JOG A;  4ORC A;  1S70 A;  4O5G A;  4FBQ A;  2AHD A;  1T70 A;  3IVE A;  2QFP A;  3QFK A;  3DSC A;  3IB8 A;  2WDE A;  2HY1 A;  3QFN A;  1TCO A;  4H2I A;  4LU9 A;  3P71 C;  4H2B A;  3DSD A;  1T71 A;  2A22 A;  2WDC A;  4LAC C;  3K7V C;  1IT6 A;  1KBP A;  3EGH A;  2KKN A;  3N5U A;  1V73 A;  5JPF A;  5JJT A;  4UWQ A;  3H60 A;  2IE3 C;  2NYL C;  4MOY A;  2Z72 A;  3H66 A;  5F3W A;  3PSN A;  1OI8 A;  2QJC A;  1HO5 A;  4ORB A;  2WDF A;  4M0V A;  4O4K A;  3THN A;  4ZX2 A;  1QHW A;  3GVE A;  3LL8 A;  3K7W C;  1QFC A;  3E7A A;  2Q8U A;  1W24 A;  3H67 A;  1WAO 1;  3H62 B;  2QFR A;  3RL5 A;  2ZBM A;  4UT3 A;  1UF3 A;  4TUG A;  4I5N C;  4H2F A;  1M63 A;  3IB7 A;  4V0V A;  3H61 A;  3DW8 C;  2IAE C;  4IL1 A;  3EGG A;  4ORA A;  4JA7 A;  3RL3 A;  3JYF A;  3ZTV A;  1U32 A;  1NNW A;  2XMO A;  1XZW A;  3HVQ A;  4YKE A;  5EQV A;  5JPE A;  1OIE A;  4H2G A;  4H1Y P;  5B8I A;  2R17 A;  4B2O A;  3QFM A;  1G5B A;  1S3M A;  3C9F A;  2HYP A;  3RL4 A;  3TGH A;  3V4Y A;  5DNY A;  5IOH A;  2BCD A;  3QFO A;  5INB A;  1SU1 A;  1JK7 A;  1HPU A;  3H64 A; 
#chains in the Genus database with same CATH topology
 3H68 A;  1HP1 A;  4UT2 A;  1II7 A;  2BDX A;  4V0W A;  4XPN A;  5HPE A;  5J28 A;  2NXF A;  4ZVZ A;  4F0Z A;  1Z2X A;  3FGA C;  1AUI A;  4HD0 A;  4DHL A;  3ICF A;  4Q7F A;  2YVT A;  1S95 A;  3AUZ A;  3QG5 C;  2Z06 A;  4OR9 A;  4DSY A;  1Z2W A;  1OID A;  2O8G A;  4FBK A;  1WAR A;  4FCX A;  5GTU A;  4KKZ A;  2ZOA A;  2WDD A;  2P6B A;  3THO B;  3CK2 A;  4O43 A;  4J6O A;  4MP0 A;  3T1I A;  3KBP A;  1MF8 A;  3AV0 A;  3H69 A;  3IVD A;  4H1S A;  5C1V A;  2NPP C;  4KBP A;  4MOV A;  2CV9 A;  2O8A A;  1S3N A;  1USH A;  1XM7 A;  2NYM C;  1FJM A;  3RQZ A;  2IE4 C;  4V0X A;  4I5L C;  4UT3 B;  3E7B A;  4DT2 A;  1UTE A;  4O24 A;  3H63 A;  4IYP C;  4LTY A;  4WWL A;  1S8E A;  4TUI A;  2BQ8 X;  2Z1A A;  4G9J A;  4NZV A;  2GJU A;  2DFJ A;  1S3L A;  3PSO A;  2HYO A;  3C5W C;  4FBW A;  4JA9 A;  3FLO A;  2USH A;  3ZU0 A;  2JOG A;  4ORC A;  1S70 A;  4O5G A;  4FBQ A;  2AHD A;  1T70 A;  3IVE A;  2QFP A;  3QFK A;  3DSC A;  3IB8 A;  2WDE A;  2HY1 A;  3QFN A;  1TCO A;  4H2I A;  4LU9 A;  3E0J A;  3P71 C;  4H2B A;  3DSD A;  1T71 A;  2YEQ A;  2A22 A;  2ZO9 B;  2WDC A;  4LAC C;  3D03 A;  3K7V C;  1IT6 A;  1KBP A;  3EGH A;  2KKN A;  3N5U A;  1V73 A;  5JPF A;  5JJT A;  4UWQ A;  3H60 A;  2IE3 C;  2NYL C;  4MOY A;  2Z72 A;  3H66 A;  5F3W A;  3PSN A;  1OI8 A;  2QJC A;  1HO5 A;  4ORB A;  2WDF A;  4M0V A;  4O4K A;  3THN A;  4ZX2 A;  1QHW A;  3GVE A;  3LL8 A;  3K7W C;  1QFC A;  3E7A A;  2Q8U A;  1W24 A;  3H67 A;  1WAO 1;  3H62 B;  2QFR A;  2DXL A;  3RL5 A;  2ZBM A;  4UT3 A;  1UF3 A;  4TUG A;  4I5N C;  4H2F A;  1M63 A;  3IB7 A;  4V0V A;  3H61 A;  3DW8 C;  2IAE C;  4IL1 A;  2DXN A;  3EGG A;  4ORA A;  4JA7 A;  3RL3 A;  3JYF A;  3ZTV A;  1U32 A;  1NNW A;  2XMO A;  1XZW A;  3HVQ A;  4YKE A;  5EQV A;  5JPE A;  1OIE A;  4H2G A;  4H1Y P;  5B8I A;  2R17 A;  4B2O A;  3QFM A;  1G5B A;  1S3M A;  3C9F A;  2HYP A;  3RL4 A;  3TGH A;  3V4Y A;  5DNY A;  5IOH A;  2BCD A;  3QFO A;  5INB A;  1SU1 A;  1JK7 A;  1HPU A;  3H64 A; 
#chains in the Genus database with same CATH homology
 3H68 A;  1HP1 A;  4UT2 A;  1II7 A;  2BDX A;  4V0W A;  4XPN A;  5HPE A;  5J28 A;  2NXF A;  4ZVZ A;  4F0Z A;  1Z2X A;  3FGA C;  1AUI A;  4HD0 A;  4DHL A;  3ICF A;  4Q7F A;  2YVT A;  1S95 A;  3AUZ A;  3QG5 C;  2Z06 A;  4OR9 A;  4DSY A;  1Z2W A;  1OID A;  2O8G A;  4FBK A;  1WAR A;  4FCX A;  5GTU A;  4KKZ A;  2ZOA A;  2WDD A;  2P6B A;  3THO B;  3CK2 A;  4O43 A;  4J6O A;  4MP0 A;  3T1I A;  3KBP A;  1MF8 A;  3AV0 A;  3H69 A;  3IVD A;  4H1S A;  5C1V A;  2NPP C;  4KBP A;  4MOV A;  2CV9 A;  2O8A A;  1S3N A;  1USH A;  1XM7 A;  2NYM C;  1FJM A;  3RQZ A;  2IE4 C;  4V0X A;  4I5L C;  4UT3 B;  3E7B A;  4DT2 A;  1UTE A;  4O24 A;  3H63 A;  4IYP C;  4LTY A;  4WWL A;  1S8E A;  4TUI A;  2BQ8 X;  2Z1A A;  4G9J A;  4NZV A;  2GJU A;  2DFJ A;  1S3L A;  3PSO A;  2HYO A;  3C5W C;  4FBW A;  4JA9 A;  3FLO A;  2USH A;  3ZU0 A;  2JOG A;  4ORC A;  1S70 A;  4O5G A;  4FBQ A;  2AHD A;  1T70 A;  3IVE A;  2QFP A;  3QFK A;  3DSC A;  3IB8 A;  2WDE A;  2HY1 A;  3QFN A;  1TCO A;  4H2I A;  4LU9 A;  3E0J A;  3P71 C;  4H2B A;  3DSD A;  1T71 A;  2YEQ A;  2A22 A;  2ZO9 B;  2WDC A;  4LAC C;  3D03 A;  3K7V C;  1IT6 A;  1KBP A;  3EGH A;  2KKN A;  3N5U A;  1V73 A;  5JPF A;  5JJT A;  4UWQ A;  3H60 A;  2IE3 C;  2NYL C;  4MOY A;  2Z72 A;  3H66 A;  5F3W A;  3PSN A;  1OI8 A;  2QJC A;  1HO5 A;  4ORB A;  2WDF A;  4M0V A;  4O4K A;  3THN A;  4ZX2 A;  1QHW A;  3GVE A;  3LL8 A;  3K7W C;  1QFC A;  3E7A A;  2Q8U A;  1W24 A;  3H67 A;  1WAO 1;  3H62 B;  2QFR A;  2DXL A;  3RL5 A;  2ZBM A;  4UT3 A;  1UF3 A;  4TUG A;  4I5N C;  4H2F A;  1M63 A;  3IB7 A;  4V0V A;  3H61 A;  3DW8 C;  2IAE C;  4IL1 A;  2DXN A;  3EGG A;  4ORA A;  4JA7 A;  3RL3 A;  3JYF A;  3ZTV A;  1U32 A;  1NNW A;  2XMO A;  1XZW A;  3HVQ A;  4YKE A;  5EQV A;  5JPE A;  1OIE A;  4H2G A;  4H1Y P;  5B8I A;  2R17 A;  4B2O A;  3QFM A;  1G5B A;  1S3M A;  3C9F A;  2HYP A;  3RL4 A;  3TGH A;  3V4Y A;  5DNY A;  5IOH A;  2BCD A;  3QFO A;  5INB A;  1SU1 A;  1JK7 A;  1HPU A;  3H64 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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