3B0AB

Crystal structure of the mouse hoil1-l-nzf in complex with linear di-ubiquitin
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
57
structure length
57
Chain Sequence
MPVGWQCPGCTFINKPTRPGCEMCCRARPETYQIPASYQPDEEERARLAGEEEALRQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Signaling protein/metal binding protein
source organism Homo sapiens
publication title Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
pubmed doi rcsb
molecule keywords Polyubiquitin-C
total genus 10
structure length 57
sequence length 57
chains with identical sequence E
ec nomenclature ec 2.3.2.31: RBR-type E3 ubiquitin transferase.
pdb deposition date 2011-06-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.140 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 3b0aB00
4XXBB 3B0AB 3P2AA 2PPTA 3B08B 2C6BA 2C6AA 2J9UB
chains in the Genus database with same CATH superfamily
1PFYA 3HOWL 1B71A 4A3GL 2CKAA 2JI1A 6RXNA 3PO2L 2JA7L 3NFPI 8RXNA 3B08B 2GMGA 2C6BA 1S2ZA 4A3JL 1K83L 4V196 1R0HA 2WB1P 1B2OA 1TWAL 3PKJA 3HOXL 3GTLL 3GTPL 3S1NL 1JYBA 3MSUA 2H12A 2HVYC 2R92L 1OWBA 3LNLA 1S30A 3B0AB 4E6YA 5AI3A 5FLML 2RFKB 3PIO1 1E8JA 3LWOB 2R7ZL 3KYYA 5MF6A 1T9OA 2M6OA 2MS3A 5AN9H 2A6HD 3I4NL 4AHXA 1S24A 2ERSA 1NXGA 3JR7A 3S1ML 3GTKL 2PPTA 1QQTA 3LWQB 2V0EA 5MFPA 3RZDL 4TPUA 4Y7NL 3MPSA 1BQ8A 5M5WL 3VPBE 2PVEA 1R0FA 2NYDA 5EINC 2ZIXA 4A93L 2XJSA 3ZG6A 5GAGc 1Y1WL 1CAAA 1VZGA 2M4YA 1LTLA 5H1Sc 3S14L 1OWCA 3PKIA 2VL6A 4JADA 3KYWA 1T9PA 2WAQP 5RXNA 1B13A 2HR5A 4YWMA 2EY4E 2DSXA 2JA5L 1RB9A 3HOYL 3S2HL 3FKIL 1YUZA 1R9TL 3LWPB 1RYQA 3PIP1 1Y1VL 5IYCL 1RDVA 2CKCA 4AR3A 3H3VM 4ZN3B 3IU3I 3H9CA 1DX8A 3LWVB 5GAEc 3KYXA 3P2AA 4AHZA 1WCML 2E2HL 1I3QL 2E2JL 1IW7D 3GTJL 1VZIA 4JAEA 2M4VA 1BE7A 5IY0A 3M4OL 5MFZA 1T9QA 2M6PA 3GTGL 1ZRPA 1R0JA 2JA8L 1I50L 3J7Y1 1H7VA 2O5JD 2V0FA 2KN9A 1LKPA 1IU6A 1YK5A 2B5ID 2A68D 2R93L 5K2ME 2PMZP 4C3JL 4A3FL 3KYUA 1FHHA 4A3KL 3HOUL 2ERJA 4XGHA 4AHWA 2E2IL 2NVYL 5C44L 3MQKB 2Y0SP 1SMWA 3A44A 1QCVA 3HOVL 3QVDA 5JVH1 3GTML 2YU9L 5M3ML 2B63L 4QIWP 3S2DL 2XJQA 5DM61 2KKDA 4RXNA 3K35A 1TWGL 5JVG1 1QYBA 4BY7L 4A3ML 4AR5A 2VUML 4AI3A 2JI3A 1TWHL 1IRNA 2Z3QB 5GADc 2J9UB 7RXNA 4XXBB 3H99A 2A69D 2NVXL 2K2DA 4BY1L 5IYDL 1I6HL 3S15L 4WFN1 3RYGA 3GTOL 1R0GA 3RZ6A 2C6AA 1VZHA 5C4XL 3RZTA 2A6ED 4GS7D 4POFA 3P8BA 4A3IL 1NXEA 4POGA 4ZN1B 2RDVA 3PZAA 3HJYB 1YUXA 3HOZL 3S1RL 4AI2A 2XJVA 1Z92B 1BFYA 4U671 1RYTA 1P7PA 1BQ9A 1TWFL 4G6BA 3WWNB 4C3IL 4Y52L 1R0IA 2BE5D 3H97A 5IYBL 1PZXA 2XJRA 1PFUA 1SMUA 5GAHc 5C4JL 2CR8A 3I4ML 1DVBA 4C2M1 3SS2A 4C3HL 1WJVA 3HKZP 4AI0A 2Z3RB 3HAXC 4K9FA 3PL5A 1IROA 3M3YL 2XJPA 3K7AL 2AQCA 3PO3L 1YK4A 2NVTL 2XJUA 2JA6L 2QL0A 1LKOA 3S1QL 1CADA 3S16L 1SMMA 4AR4A 1B2JA 5C3EL 1ODHA 4A3EL 4X6AL 2PVXA 4TVMA 4BBSL 1TWCL 4A3LL 1C09A 2V3BB 1IU5A 2PYAA 4A3CL 5IP9L 3CQZL 2APOB 3HJWB 1NNQA 4JAFA 4BBRL 1FHMA 2NVQL 1RDGA 3LWRB 3LPEB 5M5YL 3RZOL 5EIOC 3FDJA 5M5XL 1SFOL 3PWFA 4YWLA 3GTQL 5M3FL 3S17L 5FJ8L 1LKMA 4JAGA 4BXXL 4AI1A 1RWDA 4LHNA 4A3BL 5MLC3 3H0GL 2PSMC 4AHYA 4AR6A 4LHLA 4ME3A 4B8CD 5AI2A 2JI2A 1YV1A 3QQCE 2AUSB 4AYBP 3H9BA 4A3DL 3J7Z1 1PFVA 2XJTA 3WWLA 1BRFA 2AYJA 2LCQA 5IP7L 1VCXA 3KYVA 2L0ZA 5MGNA 5DM71 1PFWA 4UY81 1F4LA
chains in the Genus database with same CATH topology
2XJQA 1B71A 1YUZA 5DM61 2XJPA 2KKDA 4RXNA 3K35A 2CKAA 1YK4A 2JI1A 6RXNA 2XJUA 5JVG1 1QYBA 3NFPI 8RXNA 1RYQA 4AR5A 2QL0A 3B08B 2GMGA 3PIP1 1LKOA 2C6BA 2JI3A 1S2ZA 4AI3A 1RDVA 2CKCA 4V196 1IRNA 1CADA 1R0HA 2Z3QB 4AR3A 1SMMA 5GADc 1B2OA 4ZN3B 2J9UB 3IU3I 7RXNA 4AR4A 3PKJA 4XXBB 1B2JA 1DX8A 2A69D 1ODHA 5GAEc 3KYXA 1JYBA 3MSUA 2H12A 3P2AA 2K2DA 1OWBA 3LNLA 4AHZA 2PVXA 4TVMA 4WFN1 3RYGA 1S30A 1C09A 2V3BB 3B0AB 1IW7D 4E6YA 1IU5A 5AI3A 2PYAA 1VZIA 1R0GA 3RZ6A 2C6AA 1VZHA 4JAEA 1NNQA 4JAFA 2M4VA 3PIO1 1FHMA 3RZTA 2A6ED 1BE7A 1RDGA 5IY0A 4GS7D 1E8JA 4POFA 3LPEB 3P8BA 1NXEA 4POGA 3KYYA 5MFZA 1T9QA 5MF6A 5EIOC 1T9OA 4ZN1B 2RDVA 2M6PA 3PZAA 2M6OA 1ZRPA 2MS3A 1YUXA 2A6HD 1R0JA 5AN9H 3PWFA 4YWLA 4AHXA 4AI2A 1S24A 1Z92B 1NXGA 2ERSA 2XJVA 3J7Y1 1BFYA 1H7VA 2O5JD 2V0FA 4U671 1LKMA 2KN9A 1LKPA 1IU6A 1RYTA 2PPTA 4JAGA 1YK5A 2B5ID 2A68D 4AI1A 1RWDA 4LHNA 1BQ9A 4G6BA 5K2ME 2V0EA 5MLC3 5MFPA 4TPUA 3WWNB 2PSMC 3MPSA 1BQ8A 4AHYA 4AR6A 4LHLA 3KYUA 4ME3A 1R0IA 4B8CD 2BE5D 3VPBE 1FHHA 2PVEA 1R0FA 5AI2A 2JI2A 1YV1A 2NYDA 5EINC 2XJRA 2ZIXA 3QQCE 2ERJA 2XJSA 1SMUA 4XGHA 3ZG6A 5GAHc 5GAGc 1CAAA 1VZGA 2CR8A 2M4YA 1DVBA 4AHWA 1LTLA 5H1Sc 3J7Z1 1OWCA 2XJTA 3WWLA 3SS2A 3PKIA 1WJVA 1BRFA 1SMWA 3A44A 2VL6A 1QCVA 4JADA 4AI0A 2Z3RB 3KYWA 1T9PA 3QVDA 5JVH1 2AYJA 2LCQA 5RXNA 1B13A 1VCXA 2HR5A 3KYVA 2L0ZA 5MGNA 5DM71 4K9FA 4YWMA 1IROA 4UY81 2DSXA 1RB9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XXB B;  3B0A B;  3P2A A;  2PPT A;  3B08 B;  2C6B A;  2C6A A;  2J9U B; 
#chains in the Genus database with same CATH topology
 1PFY A;  3HOW L;  1B71 A;  4A3G L;  2CKA A;  2JI1 A;  6RXN A;  3PO2 L;  2JA7 L;  3NFP I;  8RXN A;  3B08 B;  2GMG A;  2C6B A;  1S2Z A;  4A3J L;  1K83 L;  4V19 6;  1R0H A;  2WB1 P;  1B2O A;  1TWA L;  3PKJ A;  3HOX L;  3GTL L;  3GTP L;  3S1N L;  1JYB A;  3MSU A;  2H12 A;  2HVY C;  2R92 L;  1OWB A;  3LNL A;  1S30 A;  3B0A B;  4E6Y A;  5AI3 A;  5FLM L;  2RFK B;  3PIO 1;  1E8J A;  3LWO B;  2R7Z L;  3KYY A;  5MF6 A;  1T9O A;  2M6O A;  2MS3 A;  5AN9 H;  2A6H D;  3I4N L;  4AHX A;  1S24 A;  2ERS A;  1NXG A;  3JR7 A;  3S1M L;  3GTK L;  2PPT A;  1QQT A;  3LWQ B;  2V0E A;  5MFP A;  3RZD L;  4TPU A;  4Y7N L;  3MPS A;  1BQ8 A;  5M5W L;  3VPB E;  2PVE A;  1R0F A;  2NYD A;  5EIN C;  2ZIX A;  4A93 L;  2XJS A;  3ZG6 A;  5GAG c;  1Y1W L;  1CAA A;  1VZG A;  2M4Y A;  1LTL A;  5H1S c;  3S14 L;  1OWC A;  3PKI A;  2VL6 A;  4JAD A;  3KYW A;  1T9P A;  2WAQ P;  5RXN A;  1B13 A;  2HR5 A;  4YWM A;  2EY4 E;  2DSX A;  2JA5 L;  1RB9 A;  3HOY L;  3S2H L;  3FKI L;  1YUZ A;  1R9T L;  3LWP B;  1RYQ A;  3PIP 1;  1Y1V L;  5IYC L;  1RDV A;  2CKC A;  4AR3 A;  3H3V M;  4ZN3 B;  3IU3 I;  3H9C A;  1DX8 A;  3LWV B;  5GAE c;  3KYX A;  3P2A A;  4AHZ A;  1WCM L;  2E2H L;  1I3Q L;  2E2J L;  1IW7 D;  3GTJ L;  1VZI A;  4JAE A;  2M4V A;  1BE7 A;  5IY0 A;  3M4O L;  5MFZ A;  1T9Q A;  2M6P A;  3GTG L;  1ZRP A;  1R0J A;  2JA8 L;  1I50 L;  3J7Y 1;  1H7V A;  2O5J D;  2V0F A;  2KN9 A;  1LKP A;  1IU6 A;  1YK5 A;  2B5I D;  2A68 D;  2R93 L;  5K2M E;  2PMZ P;  4C3J L;  4A3F L;  3KYU A;  1FHH A;  4A3K L;  3HOU L;  2ERJ A;  4XGH A;  4AHW A;  2E2I L;  2NVY L;  5C44 L;  3MQK B;  2Y0S P;  1SMW A;  3A44 A;  1QCV A;  3HOV L;  3QVD A;  5JVH 1;  3GTM L;  2YU9 L;  5M3M L;  2B63 L;  4QIW P;  3S2D L;  2XJQ A;  5DM6 1;  2KKD A;  4RXN A;  3K35 A;  1TWG L;  5JVG 1;  1QYB A;  4BY7 L;  4A3M L;  4AR5 A;  2VUM L;  4AI3 A;  2JI3 A;  1TWH L;  1IRN A;  2Z3Q B;  5GAD c;  2J9U B;  7RXN A;  4XXB B;  3H99 A;  2A69 D;  2NVX L;  2K2D A;  4BY1 L;  5IYD L;  1I6H L;  3S15 L;  4WFN 1;  3RYG A;  3GTO L;  1R0G A;  3RZ6 A;  2C6A A;  1VZH A;  5C4X L;  3RZT A;  2A6E D;  4GS7 D;  4POF A;  3P8B A;  4A3I L;  1NXE A;  4POG A;  4ZN1 B;  2RDV A;  3PZA A;  3HJY B;  1YUX A;  3HOZ L;  3S1R L;  4AI2 A;  2XJV A;  1Z92 B;  1BFY A;  4U67 1;  1RYT A;  1P7P A;  1BQ9 A;  1TWF L;  4G6B A;  3WWN B;  4C3I L;  4Y52 L;  1R0I A;  2BE5 D;  3H97 A;  5IYB L;  1PZX A;  2XJR A;  1PFU A;  1SMU A;  5GAH c;  5C4J L;  2CR8 A;  3I4M L;  1DVB A;  4C2M 1;  3SS2 A;  4C3H L;  1WJV A;  3HKZ P;  4AI0 A;  2Z3R B;  3HAX C;  4K9F A;  3PL5 A;  1IRO A;  3M3Y L;  2XJP A;  3K7A L;  2AQC A;  3PO3 L;  1YK4 A;  2NVT L;  2XJU A;  2JA6 L;  2QL0 A;  1LKO A;  3S1Q L;  1CAD A;  3S16 L;  1SMM A;  4AR4 A;  1B2J A;  5C3E L;  1ODH A;  4A3E L;  4X6A L;  2PVX A;  4TVM A;  4BBS L;  1TWC L;  4A3L L;  1C09 A;  2V3B B;  1IU5 A;  2PYA A;  4A3C L;  5IP9 L;  3CQZ L;  2APO B;  3HJW B;  1NNQ A;  4JAF A;  4BBR L;  1FHM A;  2NVQ L;  1RDG A;  3LWR B;  3LPE B;  5M5Y L;  3RZO L;  5EIO C;  3FDJ A;  5M5X L;  1SFO L;  3PWF A;  4YWL A;  3GTQ L;  5M3F L;  3S17 L;  5FJ8 L;  1LKM A;  4JAG A;  4BXX L;  4AI1 A;  1RWD A;  4LHN A;  4A3B L;  5MLC 3;  3H0G L;  2PSM C;  4AHY A;  4AR6 A;  4LHL A;  4ME3 A;  4B8C D;  5AI2 A;  2JI2 A;  1YV1 A;  3QQC E;  2AUS B;  4AYB P;  3H9B A;  4A3D L;  3J7Z 1;  1PFV A;  2XJT A;  3WWL A;  1BRF A;  2AYJ A;  2LCQ A;  5IP7 L;  1VCX A;  3KYV A;  2L0Z A;  5MGN A;  5DM7 1;  1PFW A;  4UY8 1;  1F4L A; 
#chains in the Genus database with same CATH homology
 2XJQ A;  1B71 A;  1YUZ A;  5DM6 1;  2XJP A;  2KKD A;  4RXN A;  3K35 A;  2CKA A;  1YK4 A;  2JI1 A;  6RXN A;  2XJU A;  5JVG 1;  1QYB A;  3NFP I;  8RXN A;  1RYQ A;  4AR5 A;  2QL0 A;  3B08 B;  2GMG A;  3PIP 1;  1LKO A;  2C6B A;  2JI3 A;  1S2Z A;  4AI3 A;  1RDV A;  2CKC A;  4V19 6;  1IRN A;  1CAD A;  1R0H A;  2Z3Q B;  4AR3 A;  1SMM A;  5GAD c;  1B2O A;  4ZN3 B;  2J9U B;  3IU3 I;  7RXN A;  4AR4 A;  3PKJ A;  4XXB B;  1B2J A;  1DX8 A;  2A69 D;  1ODH A;  5GAE c;  3KYX A;  1JYB A;  3MSU A;  2H12 A;  3P2A A;  2K2D A;  1OWB A;  3LNL A;  4AHZ A;  2PVX A;  4TVM A;  4WFN 1;  3RYG A;  1S30 A;  1C09 A;  2V3B B;  3B0A B;  1IW7 D;  4E6Y A;  1IU5 A;  5AI3 A;  2PYA A;  1VZI A;  1R0G A;  3RZ6 A;  2C6A A;  1VZH A;  4JAE A;  1NNQ A;  4JAF A;  2M4V A;  3PIO 1;  1FHM A;  3RZT A;  2A6E D;  1BE7 A;  1RDG A;  5IY0 A;  4GS7 D;  1E8J A;  4POF A;  3LPE B;  3P8B A;  1NXE A;  4POG A;  3KYY A;  5MFZ A;  1T9Q A;  5MF6 A;  5EIO C;  1T9O A;  4ZN1 B;  2RDV A;  2M6P A;  3PZA A;  2M6O A;  1ZRP A;  2MS3 A;  1YUX A;  2A6H D;  1R0J A;  5AN9 H;  3PWF A;  4YWL A;  4AHX A;  4AI2 A;  1S24 A;  1Z92 B;  1NXG A;  2ERS A;  2XJV A;  3J7Y 1;  1BFY A;  1H7V A;  2O5J D;  2V0F A;  4U67 1;  1LKM A;  2KN9 A;  1LKP A;  1IU6 A;  1RYT A;  2PPT A;  4JAG A;  1YK5 A;  2B5I D;  2A68 D;  4AI1 A;  1RWD A;  4LHN A;  1BQ9 A;  4G6B A;  5K2M E;  2V0E A;  5MLC 3;  5MFP A;  4TPU A;  3WWN B;  2PSM C;  3MPS A;  1BQ8 A;  4AHY A;  4AR6 A;  4LHL A;  3KYU A;  4ME3 A;  1R0I A;  4B8C D;  2BE5 D;  3VPB E;  1FHH A;  2PVE A;  1R0F A;  5AI2 A;  2JI2 A;  1YV1 A;  2NYD A;  5EIN C;  2XJR A;  2ZIX A;  3QQC E;  2ERJ A;  2XJS A;  1SMU A;  4XGH A;  3ZG6 A;  5GAH c;  5GAG c;  1CAA A;  1VZG A;  2CR8 A;  2M4Y A;  1DVB A;  4AHW A;  1LTL A;  5H1S c;  3J7Z 1;  1OWC A;  2XJT A;  3WWL A;  3SS2 A;  3PKI A;  1WJV A;  1BRF A;  1SMW A;  3A44 A;  2VL6 A;  1QCV A;  4JAD A;  4AI0 A;  2Z3R B;  3KYW A;  1T9P A;  3QVD A;  5JVH 1;  2AYJ A;  2LCQ A;  5RXN A;  1B13 A;  1VCX A;  2HR5 A;  3KYV A;  2L0Z A;  5MGN A;  5DM7 1;  4K9F A;  4YWM A;  1IRO A;  4UY8 1;  2DSX A;  1RB9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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