3EGGA

Crystal structure of a complex between protein phosphatase 1 alpha (pp1) and the pp1 binding and pdz domains of spinophilin
Total Genus 112
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
294
structure length
294
Chain Sequence
LNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
source organism Homo sapiens
publication title Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
pubmed doi rcsb
molecule keywords Serine/threonine-protein phosphatase PP1-alpha catalytic sub
total genus 112
structure length 294
sequence length 294
chains with identical sequence B
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2008-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3eggA00
2NYMC 4TUIA 2O8AA 5JPEA 3TGHA 2WDFA 2HYPA 4LACC 3H63A 1T70A 3GVEA 3QG5C 1HO5A 1UTEA 1OIEA 2QFPA 2IAEC 1IT6A 1OI8A 4LTYA 3C9FA 4ORCA 1HP1A 4O4KA 4J6OA 4JA9A 3V4YA 3H66A 4Q7FA 2BCDA 4O43A 3ZU0A 4KKZA 4FCXA 4G9JA 3AV0A 2Z72A 1II7A 3QFKA 4HD0A 5J28A 4IL1A 4MOVA 3DSDA 1XM7A 2GJUA 4H2BA 2Q8UA 4H1SA 4NZVA 1NNWA 3IB7A 4OR9A 4UWQA 2JOGA 4MOYA 3PSNA 2WDDA 2NXFA 4FBKA 3H69A 3KBPA 4DHLA 3P71C 2WDCA 3HVQA 4TUGA 4ORBA 3C5WC 1TCOA 2R17A 2AHDA 2DFJA 4FBQA 5F3WA 3IVDA 1KBPA 3E7BA 4I5LC 1JK7A 1S95A 2CV9A 1W24A 2BQ8X 1QFCA 2KKNA 3K7WC 2IE4C 1M63A 4H2IA 4DSYA 2P6BA 4UT3B 4ZX2A 1T71A 1WARA 4DT2A 3THOB 3E7AA 4B2OA 4V0WA 3H67A 2O8GA 1QHWA 3H61A 4JA7A 2ZBMA 4XPNA 4O5GA 2USHA 2HYOA 3DSCA 4H2FA 3H64A 1G5BA 1S3NA 3N5UA 2WDEA 1SU1A 2XMOA 1V73A 5HPEA 5JPFA 3T1IA 3IVEA 2NPPC 1OIDA 3CK2A 4I5NC 5EQVA 3H62B 2NYLC 3QFMA 4O24A 1HPUA 4ORAA 4UT3A 2QFRA 5DNYA 4UT2A 3RL3A 3IB8A 1MF8A 3THNA 3QFNA 1WAO1 2HY1A 2IE3C 4ZVZA 3RQZA 5C1VA 3H60A 3PSOA 2BDXA 3RL5A 3EGGA 4F0ZA 1Z2XA 1AUIA 1UF3A 4V0VA 5JJTA 1USHA 1FJMA 2Z06A 4V0XA 3LL8A 3FGAC 3JYFA 5GTUA 1S70A 3ICFA 4WWLA 3K7VC 3H68A 1U32A 1XZWA 3ZTVA 1Z2WA 4FBWA 2QJCA 4H1YP 1S3LA 1S3MA 3DW8C 3QFOA 4IYPC 4LU9A 4M0VA 4KBPA 5B8IA 4MP0A 5IOHA 3AUZA 4YKEA 4H2GA 2Z1AA 3RL4A 2A22A 3EGHA 5INBA 1S8EA 2YVTA
chains in the Genus database with same CATH superfamily
2NYMC 4TUIA 2O8AA 5JPEA 3TGHA 2WDFA 2HYPA 4LACC 3H63A 1T70A 3GVEA 3QG5C 1HO5A 1UTEA 1OIEA 2QFPA 2IAEC 1IT6A 1OI8A 4LTYA 3C9FA 4ORCA 1HP1A 4O4KA 4J6OA 4JA9A 3V4YA 3H66A 4Q7FA 2BCDA 2ZOAA 4O43A 3ZU0A 4KKZA 4FCXA 4G9JA 3AV0A 2Z72A 1II7A 3QFKA 4HD0A 5J28A 4IL1A 4MOVA 3DSDA 1XM7A 2GJUA 4H2BA 2Q8UA 2DXLA 4H1SA 4NZVA 1NNWA 3IB7A 4OR9A 4UWQA 2JOGA 4MOYA 3PSNA 2WDDA 2NXFA 3E0JA 4FBKA 3H69A 3KBPA 4DHLA 3P71C 2WDCA 3HVQA 4TUGA 4ORBA 3C5WC 1TCOA 2R17A 2AHDA 2DFJA 4FBQA 5F3WA 3IVDA 1KBPA 3E7BA 4I5LC 1JK7A 1S95A 2CV9A 1W24A 2BQ8X 1QFCA 2KKNA 3K7WC 2IE4C 1M63A 4H2IA 4DSYA 2YEQA 2P6BA 4UT3B 4ZX2A 1T71A 1WARA 4DT2A 3THOB 3E7AA 4B2OA 4V0WA 3H67A 2O8GA 1QHWA 3H61A 4JA7A 2ZBMA 4XPNA 4O5GA 2USHA 2HYOA 3DSCA 4H2FA 3H64A 1G5BA 1S3NA 3N5UA 2WDEA 1SU1A 2XMOA 1V73A 5HPEA 5JPFA 3T1IA 3IVEA 2NPPC 1OIDA 3CK2A 4I5NC 5EQVA 3H62B 2NYLC 3QFMA 4O24A 1HPUA 2DXNA 4ORAA 4UT3A 2QFRA 5DNYA 4UT2A 3RL3A 3IB8A 1MF8A 3THNA 3FLOA 3QFNA 1WAO1 2HY1A 2IE3C 4ZVZA 3RQZA 5C1VA 3H60A 3PSOA 2BDXA 3RL5A 3EGGA 4F0ZA 1Z2XA 1AUIA 1UF3A 4V0VA 5JJTA 1USHA 1FJMA 2Z06A 4V0XA 3LL8A 3FGAC 3JYFA 5GTUA 1S70A 3ICFA 4WWLA 3D03A 2ZO9B 3K7VC 3H68A 1U32A 1XZWA 3ZTVA 1Z2WA 4FBWA 2QJCA 4H1YP 1S3LA 1S3MA 3DW8C 3QFOA 4IYPC 4LU9A 4M0VA 4KBPA 5B8IA 4MP0A 5IOHA 3AUZA 4YKEA 4H2GA 2Z1AA 3RL4A 2A22A 3EGHA 5INBA 1S8EA 2YVTA
chains in the Genus database with same CATH topology
2NYMC 4TUIA 2O8AA 5JPEA 3TGHA 2WDFA 2HYPA 4LACC 3H63A 1T70A 3GVEA 3QG5C 1HO5A 1UTEA 1OIEA 2QFPA 2IAEC 1IT6A 1OI8A 4LTYA 3C9FA 4ORCA 1HP1A 4O4KA 4J6OA 4JA9A 3V4YA 3H66A 4Q7FA 2BCDA 2ZOAA 4O43A 3ZU0A 4KKZA 4FCXA 4G9JA 3AV0A 2Z72A 1II7A 3QFKA 4HD0A 5J28A 4IL1A 4MOVA 3DSDA 1XM7A 2GJUA 4H2BA 2Q8UA 2DXLA 4H1SA 4NZVA 1NNWA 3IB7A 4OR9A 4UWQA 2JOGA 4MOYA 3PSNA 2WDDA 2NXFA 3E0JA 4FBKA 3H69A 3KBPA 4DHLA 3P71C 2WDCA 3HVQA 4TUGA 4ORBA 3C5WC 1TCOA 2R17A 2AHDA 2DFJA 4FBQA 5F3WA 3IVDA 1KBPA 3E7BA 4I5LC 1JK7A 1S95A 2CV9A 1W24A 2BQ8X 1QFCA 2KKNA 3K7WC 2IE4C 1M63A 4H2IA 4DSYA 2YEQA 2P6BA 4UT3B 4ZX2A 1T71A 1WARA 4DT2A 3THOB 3E7AA 4B2OA 4V0WA 3H67A 2O8GA 1QHWA 3H61A 4JA7A 2ZBMA 4XPNA 4O5GA 2USHA 2HYOA 3DSCA 4H2FA 3H64A 1G5BA 1S3NA 3N5UA 2WDEA 1SU1A 2XMOA 1V73A 5HPEA 5JPFA 3T1IA 3IVEA 2NPPC 1OIDA 3CK2A 4I5NC 5EQVA 3H62B 2NYLC 3QFMA 4O24A 1HPUA 2DXNA 4ORAA 4UT3A 2QFRA 5DNYA 4UT2A 3RL3A 3IB8A 1MF8A 3THNA 3FLOA 3QFNA 1WAO1 2HY1A 2IE3C 4ZVZA 3RQZA 5C1VA 3H60A 3PSOA 2BDXA 3RL5A 3EGGA 4F0ZA 1Z2XA 1AUIA 1UF3A 4V0VA 5JJTA 1USHA 1FJMA 2Z06A 4V0XA 3LL8A 3FGAC 3JYFA 5GTUA 1S70A 3ICFA 4WWLA 3D03A 2ZO9B 3K7VC 3H68A 1U32A 1XZWA 3ZTVA 1Z2WA 4FBWA 2QJCA 4H1YP 1S3LA 1S3MA 3DW8C 3QFOA 4IYPC 4LU9A 4M0VA 4KBPA 5B8IA 4MP0A 5IOHA 3AUZA 4YKEA 4H2GA 2Z1AA 3RL4A 2A22A 3EGHA 5INBA 1S8EA 2YVTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NYM C;  4TUI A;  2O8A A;  5JPE A;  3TGH A;  2WDF A;  2HYP A;  4LAC C;  3H63 A;  1T70 A;  3GVE A;  3QG5 C;  1HO5 A;  1UTE A;  1OIE A;  2QFP A;  2IAE C;  1IT6 A;  1OI8 A;  4LTY A;  3C9F A;  4ORC A;  1HP1 A;  4O4K A;  4J6O A;  4JA9 A;  3V4Y A;  3H66 A;  4Q7F A;  2BCD A;  4O43 A;  3ZU0 A;  4KKZ A;  4FCX A;  4G9J A;  3AV0 A;  2Z72 A;  1II7 A;  3QFK A;  4HD0 A;  5J28 A;  4IL1 A;  4MOV A;  3DSD A;  1XM7 A;  2GJU A;  4H2B A;  2Q8U A;  4H1S A;  4NZV A;  1NNW A;  3IB7 A;  4OR9 A;  4UWQ A;  2JOG A;  4MOY A;  3PSN A;  2WDD A;  2NXF A;  4FBK A;  3H69 A;  3KBP A;  4DHL A;  3P71 C;  2WDC A;  3HVQ A;  4TUG A;  4ORB A;  3C5W C;  1TCO A;  2R17 A;  2AHD A;  2DFJ A;  4FBQ A;  5F3W A;  3IVD A;  1KBP A;  3E7B A;  4I5L C;  1JK7 A;  1S95 A;  2CV9 A;  1W24 A;  2BQ8 X;  1QFC A;  2KKN A;  3K7W C;  2IE4 C;  1M63 A;  4H2I A;  4DSY A;  2P6B A;  4UT3 B;  4ZX2 A;  1T71 A;  1WAR A;  4DT2 A;  3THO B;  3E7A A;  4B2O A;  4V0W A;  3H67 A;  2O8G A;  1QHW A;  3H61 A;  4JA7 A;  2ZBM A;  4XPN A;  4O5G A;  2USH A;  2HYO A;  3DSC A;  4H2F A;  3H64 A;  1G5B A;  1S3N A;  3N5U A;  2WDE A;  1SU1 A;  2XMO A;  1V73 A;  5HPE A;  5JPF A;  3T1I A;  3IVE A;  2NPP C;  1OID A;  3CK2 A;  4I5N C;  5EQV A;  3H62 B;  2NYL C;  3QFM A;  4O24 A;  1HPU A;  4ORA A;  4UT3 A;  2QFR A;  5DNY A;  4UT2 A;  3RL3 A;  3IB8 A;  1MF8 A;  3THN A;  3QFN A;  1WAO 1;  2HY1 A;  2IE3 C;  4ZVZ A;  3RQZ A;  5C1V A;  3H60 A;  3PSO A;  2BDX A;  3RL5 A;  3EGG A;  4F0Z A;  1Z2X A;  1AUI A;  1UF3 A;  4V0V A;  5JJT A;  1USH A;  1FJM A;  2Z06 A;  4V0X A;  3LL8 A;  3FGA C;  3JYF A;  5GTU A;  1S70 A;  3ICF A;  4WWL A;  3K7V C;  3H68 A;  1U32 A;  1XZW A;  3ZTV A;  1Z2W A;  4FBW A;  2QJC A;  4H1Y P;  1S3L A;  1S3M A;  3DW8 C;  3QFO A;  4IYP C;  4LU9 A;  4M0V A;  4KBP A;  5B8I A;  4MP0 A;  5IOH A;  3AUZ A;  4YKE A;  4H2G A;  2Z1A A;  3RL4 A;  2A22 A;  3EGH A;  5INB A;  1S8E A;  2YVT A; 
#chains in the Genus database with same CATH topology
 2NYM C;  4TUI A;  2O8A A;  5JPE A;  3TGH A;  2WDF A;  2HYP A;  4LAC C;  3H63 A;  1T70 A;  3GVE A;  3QG5 C;  1HO5 A;  1UTE A;  1OIE A;  2QFP A;  2IAE C;  1IT6 A;  1OI8 A;  4LTY A;  3C9F A;  4ORC A;  1HP1 A;  4O4K A;  4J6O A;  4JA9 A;  3V4Y A;  3H66 A;  4Q7F A;  2BCD A;  2ZOA A;  4O43 A;  3ZU0 A;  4KKZ A;  4FCX A;  4G9J A;  3AV0 A;  2Z72 A;  1II7 A;  3QFK A;  4HD0 A;  5J28 A;  4IL1 A;  4MOV A;  3DSD A;  1XM7 A;  2GJU A;  4H2B A;  2Q8U A;  2DXL A;  4H1S A;  4NZV A;  1NNW A;  3IB7 A;  4OR9 A;  4UWQ A;  2JOG A;  4MOY A;  3PSN A;  2WDD A;  2NXF A;  3E0J A;  4FBK A;  3H69 A;  3KBP A;  4DHL A;  3P71 C;  2WDC A;  3HVQ A;  4TUG A;  4ORB A;  3C5W C;  1TCO A;  2R17 A;  2AHD A;  2DFJ A;  4FBQ A;  5F3W A;  3IVD A;  1KBP A;  3E7B A;  4I5L C;  1JK7 A;  1S95 A;  2CV9 A;  1W24 A;  2BQ8 X;  1QFC A;  2KKN A;  3K7W C;  2IE4 C;  1M63 A;  4H2I A;  4DSY A;  2YEQ A;  2P6B A;  4UT3 B;  4ZX2 A;  1T71 A;  1WAR A;  4DT2 A;  3THO B;  3E7A A;  4B2O A;  4V0W A;  3H67 A;  2O8G A;  1QHW A;  3H61 A;  4JA7 A;  2ZBM A;  4XPN A;  4O5G A;  2USH A;  2HYO A;  3DSC A;  4H2F A;  3H64 A;  1G5B A;  1S3N A;  3N5U A;  2WDE A;  1SU1 A;  2XMO A;  1V73 A;  5HPE A;  5JPF A;  3T1I A;  3IVE A;  2NPP C;  1OID A;  3CK2 A;  4I5N C;  5EQV A;  3H62 B;  2NYL C;  3QFM A;  4O24 A;  1HPU A;  2DXN A;  4ORA A;  4UT3 A;  2QFR A;  5DNY A;  4UT2 A;  3RL3 A;  3IB8 A;  1MF8 A;  3THN A;  3FLO A;  3QFN A;  1WAO 1;  2HY1 A;  2IE3 C;  4ZVZ A;  3RQZ A;  5C1V A;  3H60 A;  3PSO A;  2BDX A;  3RL5 A;  3EGG A;  4F0Z A;  1Z2X A;  1AUI A;  1UF3 A;  4V0V A;  5JJT A;  1USH A;  1FJM A;  2Z06 A;  4V0X A;  3LL8 A;  3FGA C;  3JYF A;  5GTU A;  1S70 A;  3ICF A;  4WWL A;  3D03 A;  2ZO9 B;  3K7V C;  3H68 A;  1U32 A;  1XZW A;  3ZTV A;  1Z2W A;  4FBW A;  2QJC A;  4H1Y P;  1S3L A;  1S3M A;  3DW8 C;  3QFO A;  4IYP C;  4LU9 A;  4M0V A;  4KBP A;  5B8I A;  4MP0 A;  5IOH A;  3AUZ A;  4YKE A;  4H2G A;  2Z1A A;  3RL4 A;  2A22 A;  3EGH A;  5INB A;  1S8E A;  2YVT A; 
#chains in the Genus database with same CATH homology
 2NYM C;  4TUI A;  2O8A A;  5JPE A;  3TGH A;  2WDF A;  2HYP A;  4LAC C;  3H63 A;  1T70 A;  3GVE A;  3QG5 C;  1HO5 A;  1UTE A;  1OIE A;  2QFP A;  2IAE C;  1IT6 A;  1OI8 A;  4LTY A;  3C9F A;  4ORC A;  1HP1 A;  4O4K A;  4J6O A;  4JA9 A;  3V4Y A;  3H66 A;  4Q7F A;  2BCD A;  2ZOA A;  4O43 A;  3ZU0 A;  4KKZ A;  4FCX A;  4G9J A;  3AV0 A;  2Z72 A;  1II7 A;  3QFK A;  4HD0 A;  5J28 A;  4IL1 A;  4MOV A;  3DSD A;  1XM7 A;  2GJU A;  4H2B A;  2Q8U A;  2DXL A;  4H1S A;  4NZV A;  1NNW A;  3IB7 A;  4OR9 A;  4UWQ A;  2JOG A;  4MOY A;  3PSN A;  2WDD A;  2NXF A;  3E0J A;  4FBK A;  3H69 A;  3KBP A;  4DHL A;  3P71 C;  2WDC A;  3HVQ A;  4TUG A;  4ORB A;  3C5W C;  1TCO A;  2R17 A;  2AHD A;  2DFJ A;  4FBQ A;  5F3W A;  3IVD A;  1KBP A;  3E7B A;  4I5L C;  1JK7 A;  1S95 A;  2CV9 A;  1W24 A;  2BQ8 X;  1QFC A;  2KKN A;  3K7W C;  2IE4 C;  1M63 A;  4H2I A;  4DSY A;  2YEQ A;  2P6B A;  4UT3 B;  4ZX2 A;  1T71 A;  1WAR A;  4DT2 A;  3THO B;  3E7A A;  4B2O A;  4V0W A;  3H67 A;  2O8G A;  1QHW A;  3H61 A;  4JA7 A;  2ZBM A;  4XPN A;  4O5G A;  2USH A;  2HYO A;  3DSC A;  4H2F A;  3H64 A;  1G5B A;  1S3N A;  3N5U A;  2WDE A;  1SU1 A;  2XMO A;  1V73 A;  5HPE A;  5JPF A;  3T1I A;  3IVE A;  2NPP C;  1OID A;  3CK2 A;  4I5N C;  5EQV A;  3H62 B;  2NYL C;  3QFM A;  4O24 A;  1HPU A;  2DXN A;  4ORA A;  4UT3 A;  2QFR A;  5DNY A;  4UT2 A;  3RL3 A;  3IB8 A;  1MF8 A;  3THN A;  3FLO A;  3QFN A;  1WAO 1;  2HY1 A;  2IE3 C;  4ZVZ A;  3RQZ A;  5C1V A;  3H60 A;  3PSO A;  2BDX A;  3RL5 A;  3EGG A;  4F0Z A;  1Z2X A;  1AUI A;  1UF3 A;  4V0V A;  5JJT A;  1USH A;  1FJM A;  2Z06 A;  4V0X A;  3LL8 A;  3FGA C;  3JYF A;  5GTU A;  1S70 A;  3ICF A;  4WWL A;  3D03 A;  2ZO9 B;  3K7V C;  3H68 A;  1U32 A;  1XZW A;  3ZTV A;  1Z2W A;  4FBW A;  2QJC A;  4H1Y P;  1S3L A;  1S3M A;  3DW8 C;  3QFO A;  4IYP C;  4LU9 A;  4M0V A;  4KBP A;  5B8I A;  4MP0 A;  5IOH A;  3AUZ A;  4YKE A;  4H2G A;  2Z1A A;  3RL4 A;  2A22 A;  3EGH A;  5INB A;  1S8E A;  2YVT A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...