3FGAC

Structural basis of pp2a and sgo interaction
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
308
structure length
303
Chain Sequence
DEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVNRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRTRRTPDYFL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and function of the PP2A-shugoshin interaction
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Mus musculus
molecule keywords Serine/threonine-protein phosphatase 2A 65 kDa regulatory su
total genus 99
structure length 303
sequence length 308
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2008-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3fgaC00
4DSYA 1QHWA 4WWLA 2USHA 3JYFA 1S3LA 3E7AA 1U32A 3T1IA 3LL8A 3H66A 3H67A 4F0ZA 4O43A 2CV9A 2O8GA 2P6BA 4OR9A 3RL4A 4MOYA 4IYPC 4ORCA 1MF8A 4ORBA 4Q7FA 4J6OA 4G9JA 4LU9A 3QFKA 1Z2XA 4IL1A 1G5BA 4ZVZA 1WAO1 1S8EA 3ZU0A 3TGHA 4LACC 1OI8A 1S3MA 4I5NC 4DHLA 1HO5A 3V4YA 1SU1A 2BQ8X 4UT2A 3THOB 1KBPA 4H2IA 3GVEA 2ZBMA 4O5GA 5B8IA 5J28A 2R17A 3IVEA 1V73A 2IE3C 3H61A 3QG5C 4NZVA 5INBA 2QFRA 1IT6A 2A22A 4HD0A 4XPNA 4B2OA 1OIDA 1T71A 3C5WC 3H62B 3PSNA 5JPEA 3K7WC 4M0VA 4TUIA 3ICFA 3H63A 4MOVA 2IAEC 3QFMA 3H64A 3RL5A 2Z72A 3THNA 4KBPA 2IE4C 3KBPA 4V0WA 3AUZA 3DSCA 5JPFA 2WDDA 4MP0A 4UT3A 2HYPA 3H69A 3IB7A 1HPUA 3DSDA 3FGAC 3N5UA 4H1SA 1UTEA 4LTYA 2O8AA 1T70A 3HVQA 2NYMC 4ORAA 1OIEA 2WDFA 4H1YP 5IOHA 4TUGA 1XM7A 2DFJA 1USHA 1II7A 2JOGA 3P71C 1S95A 5EQVA 1AUIA 1WARA 3DW8C 2BCDA 4JA9A 2QJCA 2QFPA 3RL3A 1FJMA 3RQZA 4YKEA 1UF3A 1HP1A 2WDCA 4V0XA 4I5LC 1M63A 3H68A 2BDXA 2KKNA 3ZTVA 1JK7A 3H60A 5GTUA 5JJTA 2XMOA 2Z06A 3C9FA 2GJUA 3QFNA 1Z2WA 1S70A 3PSOA 4O4KA 4UWQA 4DT2A 4FBQA 5C1VA 5HPEA 4FBWA 4H2GA 4UT3B 2Q8UA 3EGHA 4O24A 5F3WA 4H2FA 2HYOA 2HY1A 2NPPC 1NNWA 4JA7A 3EGGA 4KKZA 1TCOA 4FBKA 2YVTA 4H2BA 2NXFA 5DNYA 4FCXA 3E7BA 1W24A 4ZX2A 1XZWA 2AHDA 3AV0A 3K7VC 2Z1AA 3CK2A 3IB8A 3QFOA 3IVDA 1S3NA 2WDEA 4V0VA 2NYLC 1QFCA
chains in the Genus database with same CATH superfamily
4DSYA 1QHWA 4WWLA 2ZO9B 2USHA 3JYFA 1S3LA 3E7AA 1U32A 3T1IA 3LL8A 3H66A 3H67A 4F0ZA 4O43A 2CV9A 2O8GA 2P6BA 4OR9A 3RL4A 4MOYA 4IYPC 4ORCA 1MF8A 4ORBA 4Q7FA 4J6OA 4G9JA 4LU9A 3QFKA 1Z2XA 4IL1A 1G5BA 4ZVZA 1WAO1 1S8EA 3ZU0A 3TGHA 4LACC 1OI8A 1S3MA 4I5NC 4DHLA 1HO5A 3V4YA 1SU1A 2BQ8X 4UT2A 3THOB 1KBPA 4H2IA 3GVEA 2ZBMA 4O5GA 5B8IA 5J28A 2R17A 3IVEA 1V73A 2IE3C 3H61A 3QG5C 4NZVA 5INBA 2DXLA 1IT6A 2DXNA 2QFRA 2A22A 4HD0A 4XPNA 4B2OA 1OIDA 1T71A 3C5WC 3H62B 3PSNA 5JPEA 3K7WC 4M0VA 4TUIA 3ICFA 3H63A 4MOVA 2IAEC 3QFMA 3H64A 3RL5A 2Z72A 3THNA 4KBPA 2IE4C 3FLOA 3KBPA 4V0WA 3AUZA 3DSCA 5JPFA 2WDDA 4MP0A 4UT3A 2HYPA 3H69A 3IB7A 1HPUA 3DSDA 3FGAC 3N5UA 4H1SA 1UTEA 4LTYA 2O8AA 1T70A 3HVQA 2NYMC 4ORAA 1OIEA 2WDFA 4H1YP 5IOHA 4TUGA 1XM7A 2DFJA 1USHA 1II7A 2JOGA 3P71C 1S95A 5EQVA 1AUIA 1WARA 3DW8C 2BCDA 4JA9A 2QJCA 2QFPA 3RL3A 1FJMA 3RQZA 4YKEA 2YEQA 1UF3A 1HP1A 2WDCA 4V0XA 4I5LC 1M63A 3H68A 2BDXA 2KKNA 3ZTVA 1JK7A 3H60A 5GTUA 5JJTA 2XMOA 2Z06A 3C9FA 2GJUA 3QFNA 1Z2WA 1S70A 3PSOA 4O4KA 4UWQA 4DT2A 4FBQA 5C1VA 5HPEA 4FBWA 4H2GA 4UT3B 2Q8UA 3EGHA 4O24A 5F3WA 4H2FA 3E0JA 2HYOA 2HY1A 2ZOAA 2NPPC 1NNWA 4JA7A 3EGGA 4KKZA 1TCOA 4FBKA 2YVTA 4H2BA 2NXFA 5DNYA 4FCXA 3E7BA 1W24A 4ZX2A 1XZWA 2AHDA 3AV0A 3K7VC 2Z1AA 3CK2A 3D03A 3IB8A 3QFOA 3IVDA 1S3NA 2WDEA 4V0VA 2NYLC 1QFCA
chains in the Genus database with same CATH topology
4DSYA 1QHWA 4WWLA 2ZO9B 2USHA 3JYFA 1S3LA 3E7AA 1U32A 3T1IA 3LL8A 3H66A 3H67A 4F0ZA 4O43A 2CV9A 2O8GA 2P6BA 4OR9A 3RL4A 4MOYA 4IYPC 4ORCA 1MF8A 4ORBA 4Q7FA 4J6OA 4G9JA 4LU9A 3QFKA 1Z2XA 4IL1A 1G5BA 4ZVZA 1WAO1 1S8EA 3ZU0A 3TGHA 4LACC 1OI8A 1S3MA 4I5NC 4DHLA 1HO5A 3V4YA 1SU1A 2BQ8X 4UT2A 3THOB 1KBPA 4H2IA 3GVEA 2ZBMA 4O5GA 5B8IA 5J28A 2R17A 3IVEA 1V73A 2IE3C 3H61A 3QG5C 4NZVA 5INBA 2DXLA 1IT6A 2DXNA 2QFRA 2A22A 4HD0A 4XPNA 4B2OA 1OIDA 1T71A 3C5WC 3H62B 3PSNA 5JPEA 3K7WC 4M0VA 4TUIA 3ICFA 3H63A 4MOVA 2IAEC 3QFMA 3H64A 3RL5A 2Z72A 3THNA 4KBPA 2IE4C 3FLOA 3KBPA 4V0WA 3AUZA 3DSCA 5JPFA 2WDDA 4MP0A 4UT3A 2HYPA 3H69A 3IB7A 1HPUA 3DSDA 3FGAC 3N5UA 4H1SA 1UTEA 4LTYA 2O8AA 1T70A 3HVQA 2NYMC 4ORAA 1OIEA 2WDFA 4H1YP 5IOHA 4TUGA 1XM7A 2DFJA 1USHA 1II7A 2JOGA 3P71C 1S95A 5EQVA 1AUIA 1WARA 3DW8C 2BCDA 4JA9A 2QJCA 2QFPA 3RL3A 1FJMA 3RQZA 4YKEA 2YEQA 1UF3A 1HP1A 2WDCA 4V0XA 4I5LC 1M63A 3H68A 2BDXA 2KKNA 3ZTVA 1JK7A 3H60A 5GTUA 5JJTA 2XMOA 2Z06A 3C9FA 2GJUA 3QFNA 1Z2WA 1S70A 3PSOA 4O4KA 4UWQA 4DT2A 4FBQA 5C1VA 5HPEA 4FBWA 4H2GA 4UT3B 2Q8UA 3EGHA 4O24A 5F3WA 4H2FA 3E0JA 2HYOA 2HY1A 2ZOAA 2NPPC 1NNWA 4JA7A 3EGGA 4KKZA 1TCOA 4FBKA 2YVTA 4H2BA 2NXFA 5DNYA 4FCXA 3E7BA 1W24A 4ZX2A 1XZWA 2AHDA 3AV0A 3K7VC 2Z1AA 3CK2A 3D03A 3IB8A 3QFOA 3IVDA 1S3NA 2WDEA 4V0VA 2NYLC 1QFCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DSY A;  1QHW A;  4WWL A;  2USH A;  3JYF A;  1S3L A;  3E7A A;  1U32 A;  3T1I A;  3LL8 A;  3H66 A;  3H67 A;  4F0Z A;  4O43 A;  2CV9 A;  2O8G A;  2P6B A;  4OR9 A;  3RL4 A;  4MOY A;  4IYP C;  4ORC A;  1MF8 A;  4ORB A;  4Q7F A;  4J6O A;  4G9J A;  4LU9 A;  3QFK A;  1Z2X A;  4IL1 A;  1G5B A;  4ZVZ A;  1WAO 1;  1S8E A;  3ZU0 A;  3TGH A;  4LAC C;  1OI8 A;  1S3M A;  4I5N C;  4DHL A;  1HO5 A;  3V4Y A;  1SU1 A;  2BQ8 X;  4UT2 A;  3THO B;  1KBP A;  4H2I A;  3GVE A;  2ZBM A;  4O5G A;  5B8I A;  5J28 A;  2R17 A;  3IVE A;  1V73 A;  2IE3 C;  3H61 A;  3QG5 C;  4NZV A;  5INB A;  2QFR A;  1IT6 A;  2A22 A;  4HD0 A;  4XPN A;  4B2O A;  1OID A;  1T71 A;  3C5W C;  3H62 B;  3PSN A;  5JPE A;  3K7W C;  4M0V A;  4TUI A;  3ICF A;  3H63 A;  4MOV A;  2IAE C;  3QFM A;  3H64 A;  3RL5 A;  2Z72 A;  3THN A;  4KBP A;  2IE4 C;  3KBP A;  4V0W A;  3AUZ A;  3DSC A;  5JPF A;  2WDD A;  4MP0 A;  4UT3 A;  2HYP A;  3H69 A;  3IB7 A;  1HPU A;  3DSD A;  3FGA C;  3N5U A;  4H1S A;  1UTE A;  4LTY A;  2O8A A;  1T70 A;  3HVQ A;  2NYM C;  4ORA A;  1OIE A;  2WDF A;  4H1Y P;  5IOH A;  4TUG A;  1XM7 A;  2DFJ A;  1USH A;  1II7 A;  2JOG A;  3P71 C;  1S95 A;  5EQV A;  1AUI A;  1WAR A;  3DW8 C;  2BCD A;  4JA9 A;  2QJC A;  2QFP A;  3RL3 A;  1FJM A;  3RQZ A;  4YKE A;  1UF3 A;  1HP1 A;  2WDC A;  4V0X A;  4I5L C;  1M63 A;  3H68 A;  2BDX A;  2KKN A;  3ZTV A;  1JK7 A;  3H60 A;  5GTU A;  5JJT A;  2XMO A;  2Z06 A;  3C9F A;  2GJU A;  3QFN A;  1Z2W A;  1S70 A;  3PSO A;  4O4K A;  4UWQ A;  4DT2 A;  4FBQ A;  5C1V A;  5HPE A;  4FBW A;  4H2G A;  4UT3 B;  2Q8U A;  3EGH A;  4O24 A;  5F3W A;  4H2F A;  2HYO A;  2HY1 A;  2NPP C;  1NNW A;  4JA7 A;  3EGG A;  4KKZ A;  1TCO A;  4FBK A;  2YVT A;  4H2B A;  2NXF A;  5DNY A;  4FCX A;  3E7B A;  1W24 A;  4ZX2 A;  1XZW A;  2AHD A;  3AV0 A;  3K7V C;  2Z1A A;  3CK2 A;  3IB8 A;  3QFO A;  3IVD A;  1S3N A;  2WDE A;  4V0V A;  2NYL C;  1QFC A; 
#chains in the Genus database with same CATH topology
 4DSY A;  1QHW A;  4WWL A;  2ZO9 B;  2USH A;  3JYF A;  1S3L A;  3E7A A;  1U32 A;  3T1I A;  3LL8 A;  3H66 A;  3H67 A;  4F0Z A;  4O43 A;  2CV9 A;  2O8G A;  2P6B A;  4OR9 A;  3RL4 A;  4MOY A;  4IYP C;  4ORC A;  1MF8 A;  4ORB A;  4Q7F A;  4J6O A;  4G9J A;  4LU9 A;  3QFK A;  1Z2X A;  4IL1 A;  1G5B A;  4ZVZ A;  1WAO 1;  1S8E A;  3ZU0 A;  3TGH A;  4LAC C;  1OI8 A;  1S3M A;  4I5N C;  4DHL A;  1HO5 A;  3V4Y A;  1SU1 A;  2BQ8 X;  4UT2 A;  3THO B;  1KBP A;  4H2I A;  3GVE A;  2ZBM A;  4O5G A;  5B8I A;  5J28 A;  2R17 A;  3IVE A;  1V73 A;  2IE3 C;  3H61 A;  3QG5 C;  4NZV A;  5INB A;  2DXL A;  1IT6 A;  2DXN A;  2QFR A;  2A22 A;  4HD0 A;  4XPN A;  4B2O A;  1OID A;  1T71 A;  3C5W C;  3H62 B;  3PSN A;  5JPE A;  3K7W C;  4M0V A;  4TUI A;  3ICF A;  3H63 A;  4MOV A;  2IAE C;  3QFM A;  3H64 A;  3RL5 A;  2Z72 A;  3THN A;  4KBP A;  2IE4 C;  3FLO A;  3KBP A;  4V0W A;  3AUZ A;  3DSC A;  5JPF A;  2WDD A;  4MP0 A;  4UT3 A;  2HYP A;  3H69 A;  3IB7 A;  1HPU A;  3DSD A;  3FGA C;  3N5U A;  4H1S A;  1UTE A;  4LTY A;  2O8A A;  1T70 A;  3HVQ A;  2NYM C;  4ORA A;  1OIE A;  2WDF A;  4H1Y P;  5IOH A;  4TUG A;  1XM7 A;  2DFJ A;  1USH A;  1II7 A;  2JOG A;  3P71 C;  1S95 A;  5EQV A;  1AUI A;  1WAR A;  3DW8 C;  2BCD A;  4JA9 A;  2QJC A;  2QFP A;  3RL3 A;  1FJM A;  3RQZ A;  4YKE A;  2YEQ A;  1UF3 A;  1HP1 A;  2WDC A;  4V0X A;  4I5L C;  1M63 A;  3H68 A;  2BDX A;  2KKN A;  3ZTV A;  1JK7 A;  3H60 A;  5GTU A;  5JJT A;  2XMO A;  2Z06 A;  3C9F A;  2GJU A;  3QFN A;  1Z2W A;  1S70 A;  3PSO A;  4O4K A;  4UWQ A;  4DT2 A;  4FBQ A;  5C1V A;  5HPE A;  4FBW A;  4H2G A;  4UT3 B;  2Q8U A;  3EGH A;  4O24 A;  5F3W A;  4H2F A;  3E0J A;  2HYO A;  2HY1 A;  2ZOA A;  2NPP C;  1NNW A;  4JA7 A;  3EGG A;  4KKZ A;  1TCO A;  4FBK A;  2YVT A;  4H2B A;  2NXF A;  5DNY A;  4FCX A;  3E7B A;  1W24 A;  4ZX2 A;  1XZW A;  2AHD A;  3AV0 A;  3K7V C;  2Z1A A;  3CK2 A;  3D03 A;  3IB8 A;  3QFO A;  3IVD A;  1S3N A;  2WDE A;  4V0V A;  2NYL C;  1QFC A; 
#chains in the Genus database with same CATH homology
 4DSY A;  1QHW A;  4WWL A;  2ZO9 B;  2USH A;  3JYF A;  1S3L A;  3E7A A;  1U32 A;  3T1I A;  3LL8 A;  3H66 A;  3H67 A;  4F0Z A;  4O43 A;  2CV9 A;  2O8G A;  2P6B A;  4OR9 A;  3RL4 A;  4MOY A;  4IYP C;  4ORC A;  1MF8 A;  4ORB A;  4Q7F A;  4J6O A;  4G9J A;  4LU9 A;  3QFK A;  1Z2X A;  4IL1 A;  1G5B A;  4ZVZ A;  1WAO 1;  1S8E A;  3ZU0 A;  3TGH A;  4LAC C;  1OI8 A;  1S3M A;  4I5N C;  4DHL A;  1HO5 A;  3V4Y A;  1SU1 A;  2BQ8 X;  4UT2 A;  3THO B;  1KBP A;  4H2I A;  3GVE A;  2ZBM A;  4O5G A;  5B8I A;  5J28 A;  2R17 A;  3IVE A;  1V73 A;  2IE3 C;  3H61 A;  3QG5 C;  4NZV A;  5INB A;  2DXL A;  1IT6 A;  2DXN A;  2QFR A;  2A22 A;  4HD0 A;  4XPN A;  4B2O A;  1OID A;  1T71 A;  3C5W C;  3H62 B;  3PSN A;  5JPE A;  3K7W C;  4M0V A;  4TUI A;  3ICF A;  3H63 A;  4MOV A;  2IAE C;  3QFM A;  3H64 A;  3RL5 A;  2Z72 A;  3THN A;  4KBP A;  2IE4 C;  3FLO A;  3KBP A;  4V0W A;  3AUZ A;  3DSC A;  5JPF A;  2WDD A;  4MP0 A;  4UT3 A;  2HYP A;  3H69 A;  3IB7 A;  1HPU A;  3DSD A;  3FGA C;  3N5U A;  4H1S A;  1UTE A;  4LTY A;  2O8A A;  1T70 A;  3HVQ A;  2NYM C;  4ORA A;  1OIE A;  2WDF A;  4H1Y P;  5IOH A;  4TUG A;  1XM7 A;  2DFJ A;  1USH A;  1II7 A;  2JOG A;  3P71 C;  1S95 A;  5EQV A;  1AUI A;  1WAR A;  3DW8 C;  2BCD A;  4JA9 A;  2QJC A;  2QFP A;  3RL3 A;  1FJM A;  3RQZ A;  4YKE A;  2YEQ A;  1UF3 A;  1HP1 A;  2WDC A;  4V0X A;  4I5L C;  1M63 A;  3H68 A;  2BDX A;  2KKN A;  3ZTV A;  1JK7 A;  3H60 A;  5GTU A;  5JJT A;  2XMO A;  2Z06 A;  3C9F A;  2GJU A;  3QFN A;  1Z2W A;  1S70 A;  3PSO A;  4O4K A;  4UWQ A;  4DT2 A;  4FBQ A;  5C1V A;  5HPE A;  4FBW A;  4H2G A;  4UT3 B;  2Q8U A;  3EGH A;  4O24 A;  5F3W A;  4H2F A;  3E0J A;  2HYO A;  2HY1 A;  2ZOA A;  2NPP C;  1NNW A;  4JA7 A;  3EGG A;  4KKZ A;  1TCO A;  4FBK A;  2YVT A;  4H2B A;  2NXF A;  5DNY A;  4FCX A;  3E7B A;  1W24 A;  4ZX2 A;  1XZW A;  2AHD A;  3AV0 A;  3K7V C;  2Z1A A;  3CK2 A;  3D03 A;  3IB8 A;  3QFO A;  3IVD A;  1S3N A;  2WDE A;  4V0V A;  2NYL C;  1QFC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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