3HOWL

Complete rna polymerase ii elongation complex iii with a t-u mismatch and a frayed rna 3'-uridine
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
44
structure length
44
Chain Sequence
LKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
pubmed doi rcsb
molecule tags Transcription,transferase/dna/rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 2
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2009-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 3howL00
5IYCL 2JA8L 3HOXL 4A3ML 1WCML 3HKZP 4BBSL 4BY1L 1TWFL 3RZDL 2VUML 3I4ML 3S1NL 1R9TL 5C4JL 4A3LL 3M3YL 4A3EL 3GTPL 2E2IL 3HOYL 2YU9L 4AYBP 2R93L 4A3KL 1TWAL 4Y7NL 5FLML 2JA7L 2E2JL 5M5WL 1I3QL 1TWHL 3S17L 2NVQL 4C2M1 1TWCL 4BXXL 3K7AL 2NVYL 3S14L 3S2HL 5C44L 5M5YL 4A3IL 1Y1WL 3CQZL 1I50L 3GTLL 1SFOL 3HOVL 3GTKL 3RZOL 2JA6L 5IP9L 5M5XL 3S16L 4Y52L 4A3DL 4A3CL 2JA5L 1K83L 3S2DL 2WAQP 2R92L 4BBRL 3GTGL 3PO3L 4A93L 3FKIL 3I4NL 4X6AL 4QIWP 5IYBL 1Y1VL 4C3JL 5C3EL 2NVTL 5FJ8L 3HOWL 3HOUL 3S1RL 3H0GL 4A3JL 3M4OL 3S1QL 5C4XL 3GTJL 4A3BL 4A3FL 2PMZP 2B63L 2WB1P 5IYDL 1I6HL 2R7ZL 3HOZL 3S15L 4C3HL 5M3FL 3S1ML 3GTQL 4A3GL 3GTML 5M3ML 3GTOL 4BY7L 2Y0SP 3H3VM 3PO2L 4C3IL 5IP7L 1TWGL 2E2HL 2NVXL
chains in the Genus database with same CATH superfamily
1SMMA 3HOXL 5MF6A 2B5ID 3RYGA 3RZDL 5MLC3 1ODHA 1SMUA 1LTLA 2DSXA 3QQCE 1E8JA 4E6YA 2XJTA 2AQCA 4AI1A 3KYXA 1TWAL 1R0FA 1NXEA 2JA7L 6RXNA 1I3QL 4AR5A 1IRNA 2M6OA 4C2M1 1VZHA 1TWCL 1B2JA 4BXXL 3K7AL 2NVYL 3S2HL 4JAEA 4LHNA 3H9CA 3LWOB 5M5YL 4B8CD 1DVBA 2L0ZA 5AI3A 3RZOL 3HJWB 2JA6L 5EIOC 5IP9L 4AHWA 3PIP1 3SS2A 2R92L 3WWLA 3B0AB 2V3BB 2Z3QB 8RXNA 1QQTA 5MFZA 4AR3A 5GADc 5H1Sc 5FJ8L 3HOWL 7RXNA 4K9FA 4GS7D 3S1QL 5C4XL 3GTJL 2Z3RB 2B63L 3RZTA 1I6HL 4YWMA 2R7ZL 3H99A 3WWNB 4AHZA 3PL5A 2XJRA 1R0GA 1R0IA 1YUZA 1NNQA 1P7PA 1S2ZA 3LWPB 3PO2L 2ERJA 1FHHA 2NVXL 2JA8L 1YV1A 1C09A 1B71A 5RXNA 4BBSL 4BY1L 2A6ED 2ERSA 3M3YL 4A3EL 1PFYA 1YUXA 4AYBP 2R93L 4A3KL 5DM71 2NYDA 5MGNA 2RFKB 2E2JL 5M5WL 4V196 2PVXA 5IY0A 3S17L 2NVQL 4JAFA 1H7VA 1FHMA 1VZIA 3LWRB 2A6HD 1CADA 4RXNA 2PSMC 1T9PA 1BE7A 1QCVA 2A69D 2XJSA 1Y1WL 2APOB 2VL6A 1RDVA 1B13A 3P2AA 5M5XL 4U671 2MS3A 4Y52L 2JA5L 1RDGA 1SMWA 3GTGL 3PO3L 4ME3A 1T9OA 4X6AL 4QIWP 2J9UB 3LPEB 5C3EL 3S1RL 1LKOA 2C6AA 3M4OL 1NXGA 5EINC 3QVDA 1PFUA 2PMZP 4TVMA 1RB9A 4JAGA 2CR8A 5JVG1 3S15L 3P8BA 2XJPA 1IROA 3GTQL 3H97A 2LCQA 4AHYA 2JI2A 3GTML 1IU5A 3LWVB 2O5JD 4BY7L 2Y0SP 1BQ9A 5IYCL 3J7Y1 1R0HA 3HKZP 3K35A 1TWFL 2VUML 3S1NL 2H12A 4AI2A 5C4JL 3KYVA 3GTPL 2PPTA 3HOYL 2YU9L 1RYTA 1IU6A 3J7Z1 4LHLA 4Y7NL 4WFN1 1T9QA 1VZGA 5GAHc 5JVH1 4YWLA 2ZIXA 1TWHL 2HVYC 3LWQB 4AI3A 4AHXA 2PYAA 3JR7A 3VPBE 2K2DA 3S14L 1R0JA 2KN9A 5C44L 1BQ8A 3PKJA 2C6BA 4A3IL 1BFYA 4POGA 3GTLL 2RDVA 1SFOL 3KYWA 3HOVL 3GTKL 3A44A 4A3DL 4A3CL 4XXBB 1K83L 3S2DL 4JADA 3FKIL 3I4NL 2M4VA 3FDJA 2HR5A 5AI2A 1F4LA 2KKDA 2JI3A 4C3JL 3HOUL 4AR4A 2CKAA 3H0GL 1S30A 1RWDA 4A3BL 1DX8A 2AYJA 3LNLA 2WB1P 1PZXA 1VCXA 2XJUA 2M4YA 1LKPA 1ZRPA 4C3HL 5M3FL 2PVEA 3S1ML 3KYYA 2M6PA 4A3GL 4UY81 2XJVA 1RYQA 1TWGL 4AR6A 2CKCA 5K2ME 2QL0A 5MFPA 4A3ML 1WCML 3PWFA 2EY4E 3H9BA 3I4ML 2XJQA 3HAXC 1R9TL 3PZAA 4A3LL 1LKMA 1QYBA 5GAGc 1PFWA 2E2IL 2BE5D 1YK5A 1OWCA 5FLML 5AN9H 3PKIA 3NFPI 2AUSB 1YK4A 4XGHA 1JYBA 3KYUA 3MPSA 5GAEc 1BRFA 1S24A 1IW7D 3CQZL 1I50L 3HJYB 3S16L 3IU3I 4G6BA 4AI0A 2V0FA 1WJVA 2WAQP 4BBRL 3RZ6A 4POFA 4A93L 3MSUA 2GMGA 5IYBL 1Y1VL 1CAAA 2A68D 2NVTL 4ZN1B 4A3JL 2V0EA 3MQKB 1B2OA 4A3FL 3ZG6A 5IYDL 3B08B 1OWBA 3HOZL 4ZN3B 1PFVA 5DM61 2JI1A 5M3ML 3GTOL 3H3VM 4TPUA 1Z92B 5IP7L 4C3IL 3PIO1 2E2HL
chains in the Genus database with same CATH topology
5IYCL 2JA8L 3HOXL 4A3ML 1WCML 3HKZP 4BBSL 4BY1L 1TWFL 3RZDL 2VUML 3I4ML 3S1NL 1R9TL 5C4JL 4A3LL 3M3YL 4A3EL 3GTPL 2E2IL 3HOYL 2YU9L 4AYBP 2R93L 4A3KL 1TWAL 4Y7NL 5FLML 2JA7L 2E2JL 5M5WL 1I3QL 1TWHL 3S17L 2NVQL 4C2M1 1TWCL 4BXXL 3K7AL 2NVYL 3S14L 3S2HL 5C44L 5M5YL 4A3IL 1Y1WL 3CQZL 1I50L 3GTLL 1SFOL 3HOVL 3GTKL 3RZOL 2JA6L 5IP9L 5M5XL 3S16L 4Y52L 4A3DL 4A3CL 2JA5L 1K83L 3S2DL 2WAQP 2R92L 4BBRL 3GTGL 3PO3L 4A93L 3FKIL 3I4NL 4X6AL 4QIWP 5IYBL 1Y1VL 4C3JL 5C3EL 2NVTL 5FJ8L 3HOWL 3HOUL 3S1RL 3H0GL 4A3JL 3M4OL 3S1QL 5C4XL 3GTJL 4A3BL 4A3FL 2PMZP 2B63L 2WB1P 5IYDL 1I6HL 2R7ZL 3HOZL 3S15L 4C3HL 5M3FL 3S1ML 3GTQL 4A3GL 3GTML 5M3ML 3GTOL 4BY7L 2Y0SP 3H3VM 3PO2L 4C3IL 5IP7L 1TWGL 2E2HL 2NVXL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IYC L;  2JA8 L;  3HOX L;  4A3M L;  1WCM L;  3HKZ P;  4BBS L;  4BY1 L;  1TWF L;  3RZD L;  2VUM L;  3I4M L;  3S1N L;  1R9T L;  5C4J L;  4A3L L;  3M3Y L;  4A3E L;  3GTP L;  2E2I L;  3HOY L;  2YU9 L;  4AYB P;  2R93 L;  4A3K L;  1TWA L;  4Y7N L;  5FLM L;  2JA7 L;  2E2J L;  5M5W L;  1I3Q L;  1TWH L;  3S17 L;  2NVQ L;  4C2M 1;  1TWC L;  4BXX L;  3K7A L;  2NVY L;  3S14 L;  3S2H L;  5C44 L;  5M5Y L;  4A3I L;  1Y1W L;  3CQZ L;  1I50 L;  3GTL L;  1SFO L;  3HOV L;  3GTK L;  3RZO L;  2JA6 L;  5IP9 L;  5M5X L;  3S16 L;  4Y52 L;  4A3D L;  4A3C L;  2JA5 L;  1K83 L;  3S2D L;  2WAQ P;  2R92 L;  4BBR L;  3GTG L;  3PO3 L;  4A93 L;  3FKI L;  3I4N L;  4X6A L;  4QIW P;  5IYB L;  1Y1V L;  4C3J L;  5C3E L;  2NVT L;  5FJ8 L;  3HOW L;  3HOU L;  3S1R L;  3H0G L;  4A3J L;  3M4O L;  3S1Q L;  5C4X L;  3GTJ L;  4A3B L;  4A3F L;  2PMZ P;  2B63 L;  2WB1 P;  5IYD L;  1I6H L;  2R7Z L;  3HOZ L;  3S15 L;  4C3H L;  5M3F L;  3S1M L;  3GTQ L;  4A3G L;  3GTM L;  5M3M L;  3GTO L;  4BY7 L;  2Y0S P;  3H3V M;  3PO2 L;  4C3I L;  5IP7 L;  1TWG L;  2E2H L;  2NVX L; 
#chains in the Genus database with same CATH topology
 1SMM A;  3HOX L;  5MF6 A;  2B5I D;  3RYG A;  3RZD L;  5MLC 3;  1ODH A;  1SMU A;  1LTL A;  2DSX A;  3QQC E;  1E8J A;  4E6Y A;  2XJT A;  2AQC A;  4AI1 A;  3KYX A;  1TWA L;  1R0F A;  1NXE A;  2JA7 L;  6RXN A;  1I3Q L;  4AR5 A;  1IRN A;  2M6O A;  4C2M 1;  1VZH A;  1TWC L;  1B2J A;  4BXX L;  3K7A L;  2NVY L;  3S2H L;  4JAE A;  4LHN A;  3H9C A;  3LWO B;  5M5Y L;  4B8C D;  1DVB A;  2L0Z A;  5AI3 A;  3RZO L;  3HJW B;  2JA6 L;  5EIO C;  5IP9 L;  4AHW A;  3PIP 1;  3SS2 A;  2R92 L;  3WWL A;  3B0A B;  2V3B B;  2Z3Q B;  8RXN A;  1QQT A;  5MFZ A;  4AR3 A;  5GAD c;  5H1S c;  5FJ8 L;  3HOW L;  7RXN A;  4K9F A;  4GS7 D;  3S1Q L;  5C4X L;  3GTJ L;  2Z3R B;  2B63 L;  3RZT A;  1I6H L;  4YWM A;  2R7Z L;  3H99 A;  3WWN B;  4AHZ A;  3PL5 A;  2XJR A;  1R0G A;  1R0I A;  1YUZ A;  1NNQ A;  1P7P A;  1S2Z A;  3LWP B;  3PO2 L;  2ERJ A;  1FHH A;  2NVX L;  2JA8 L;  1YV1 A;  1C09 A;  1B71 A;  5RXN A;  4BBS L;  4BY1 L;  2A6E D;  2ERS A;  3M3Y L;  4A3E L;  1PFY A;  1YUX A;  4AYB P;  2R93 L;  4A3K L;  5DM7 1;  2NYD A;  5MGN A;  2RFK B;  2E2J L;  5M5W L;  4V19 6;  2PVX A;  5IY0 A;  3S17 L;  2NVQ L;  4JAF A;  1H7V A;  1FHM A;  1VZI A;  3LWR B;  2A6H D;  1CAD A;  4RXN A;  2PSM C;  1T9P A;  1BE7 A;  1QCV A;  2A69 D;  2XJS A;  1Y1W L;  2APO B;  2VL6 A;  1RDV A;  1B13 A;  3P2A A;  5M5X L;  4U67 1;  2MS3 A;  4Y52 L;  2JA5 L;  1RDG A;  1SMW A;  3GTG L;  3PO3 L;  4ME3 A;  1T9O A;  4X6A L;  4QIW P;  2J9U B;  3LPE B;  5C3E L;  3S1R L;  1LKO A;  2C6A A;  3M4O L;  1NXG A;  5EIN C;  3QVD A;  1PFU A;  2PMZ P;  4TVM A;  1RB9 A;  4JAG A;  2CR8 A;  5JVG 1;  3S15 L;  3P8B A;  2XJP A;  1IRO A;  3GTQ L;  3H97 A;  2LCQ A;  4AHY A;  2JI2 A;  3GTM L;  1IU5 A;  3LWV B;  2O5J D;  4BY7 L;  2Y0S P;  1BQ9 A;  5IYC L;  3J7Y 1;  1R0H A;  3HKZ P;  3K35 A;  1TWF L;  2VUM L;  3S1N L;  2H12 A;  4AI2 A;  5C4J L;  3KYV A;  3GTP L;  2PPT A;  3HOY L;  2YU9 L;  1RYT A;  1IU6 A;  3J7Z 1;  4LHL A;  4Y7N L;  4WFN 1;  1T9Q A;  1VZG A;  5GAH c;  5JVH 1;  4YWL A;  2ZIX A;  1TWH L;  2HVY C;  3LWQ B;  4AI3 A;  4AHX A;  2PYA A;  3JR7 A;  3VPB E;  2K2D A;  3S14 L;  1R0J A;  2KN9 A;  5C44 L;  1BQ8 A;  3PKJ A;  2C6B A;  4A3I L;  1BFY A;  4POG A;  3GTL L;  2RDV A;  1SFO L;  3KYW A;  3HOV L;  3GTK L;  3A44 A;  4A3D L;  4A3C L;  4XXB B;  1K83 L;  3S2D L;  4JAD A;  3FKI L;  3I4N L;  2M4V A;  3FDJ A;  2HR5 A;  5AI2 A;  1F4L A;  2KKD A;  2JI3 A;  4C3J L;  3HOU L;  4AR4 A;  2CKA A;  3H0G L;  1S30 A;  1RWD A;  4A3B L;  1DX8 A;  2AYJ A;  3LNL A;  2WB1 P;  1PZX A;  1VCX A;  2XJU A;  2M4Y A;  1LKP A;  1ZRP A;  4C3H L;  5M3F L;  2PVE A;  3S1M L;  3KYY A;  2M6P A;  4A3G L;  4UY8 1;  2XJV A;  1RYQ A;  1TWG L;  4AR6 A;  2CKC A;  5K2M E;  2QL0 A;  5MFP A;  4A3M L;  1WCM L;  3PWF A;  2EY4 E;  3H9B A;  3I4M L;  2XJQ A;  3HAX C;  1R9T L;  3PZA A;  4A3L L;  1LKM A;  1QYB A;  5GAG c;  1PFW A;  2E2I L;  2BE5 D;  1YK5 A;  1OWC A;  5FLM L;  5AN9 H;  3PKI A;  3NFP I;  2AUS B;  1YK4 A;  4XGH A;  1JYB A;  3KYU A;  3MPS A;  5GAE c;  1BRF A;  1S24 A;  1IW7 D;  3CQZ L;  1I50 L;  3HJY B;  3S16 L;  3IU3 I;  4G6B A;  4AI0 A;  2V0F A;  1WJV A;  2WAQ P;  4BBR L;  3RZ6 A;  4POF A;  4A93 L;  3MSU A;  2GMG A;  5IYB L;  1Y1V L;  1CAA A;  2A68 D;  2NVT L;  4ZN1 B;  4A3J L;  2V0E A;  3MQK B;  1B2O A;  4A3F L;  3ZG6 A;  5IYD L;  3B08 B;  1OWB A;  3HOZ L;  4ZN3 B;  1PFV A;  5DM6 1;  2JI1 A;  5M3M L;  3GTO L;  3H3V M;  4TPU A;  1Z92 B;  5IP7 L;  4C3I L;  3PIO 1;  2E2H L; 
#chains in the Genus database with same CATH homology
 5IYC L;  2JA8 L;  3HOX L;  4A3M L;  1WCM L;  3HKZ P;  4BBS L;  4BY1 L;  1TWF L;  3RZD L;  2VUM L;  3I4M L;  3S1N L;  1R9T L;  5C4J L;  4A3L L;  3M3Y L;  4A3E L;  3GTP L;  2E2I L;  3HOY L;  2YU9 L;  4AYB P;  2R93 L;  4A3K L;  1TWA L;  4Y7N L;  5FLM L;  2JA7 L;  2E2J L;  5M5W L;  1I3Q L;  1TWH L;  3S17 L;  2NVQ L;  4C2M 1;  1TWC L;  4BXX L;  3K7A L;  2NVY L;  3S14 L;  3S2H L;  5C44 L;  5M5Y L;  4A3I L;  1Y1W L;  3CQZ L;  1I50 L;  3GTL L;  1SFO L;  3HOV L;  3GTK L;  3RZO L;  2JA6 L;  5IP9 L;  5M5X L;  3S16 L;  4Y52 L;  4A3D L;  4A3C L;  2JA5 L;  1K83 L;  3S2D L;  2WAQ P;  2R92 L;  4BBR L;  3GTG L;  3PO3 L;  4A93 L;  3FKI L;  3I4N L;  4X6A L;  4QIW P;  5IYB L;  1Y1V L;  4C3J L;  5C3E L;  2NVT L;  5FJ8 L;  3HOW L;  3HOU L;  3S1R L;  3H0G L;  4A3J L;  3M4O L;  3S1Q L;  5C4X L;  3GTJ L;  4A3B L;  4A3F L;  2PMZ P;  2B63 L;  2WB1 P;  5IYD L;  1I6H L;  2R7Z L;  3HOZ L;  3S15 L;  4C3H L;  5M3F L;  3S1M L;  3GTQ L;  4A3G L;  3GTM L;  5M3M L;  3GTO L;  4BY7 L;  2Y0S P;  3H3V M;  3PO2 L;  4C3I L;  5IP7 L;  1TWG L;  2E2H L;  2NVX L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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