3IB8A

Crystal structure of full length rv0805 in complex with 5'-amp
Total Genus 90
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
295
structure length
295
Chain Sequence
LRAAEHPRPDYVLLHISDTHLIGGDRRLYGAVDADDRLGELLEQLNQSGLRPDAIVFTGDLADKGEPAAYRKLRGLVEPFAAQLGAELVWVMGNHDDRAELRKFLLDEAPSMAPLDRVCMIDGLRIIVLDTSVPGHHHGEIRASQLGWLAEELATPAPDGTILALHHPPIPSVLDMAVTVELRDQAALGRVLRGTDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVAAGGTRGRDGAQGCNLVHVYPDTVVHSVIPLGGGETVGTFVSPGQARRKIAESGIFIEPSRRD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
publication title A mycobacterial cyclic AMP phosphodiesterase that moonlights as a modifier of cell wall permeability
pubmed doi rcsb
molecule keywords Icc protein
total genus 90
structure length 295
sequence length 295
ec nomenclature ec 3.1.4.53: 3',5'-cyclic-AMP phosphodiesterase.
pdb deposition date 2009-07-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3ib8A00
4I5LC 3CK2A 4IYPC 4M0VA 3GVEA 1FJMA 2BCDA 3H61A 3ZU0A 1UTEA 4MOYA 2HYPA 5J28A 3IVEA 1S95A 4DHLA 4UT3A 2QFPA 3H64A 4HD0A 4H1YP 2NYLC 4MOVA 4H2FA 4DT2A 4V0VA 4TUGA 3H60A 5INBA 2XMOA 1S3MA 1HP1A 5HPEA 1SU1A 4UT3B 1Z2WA 4DSYA 2Z72A 3QFOA 3N5UA 3RL5A 1UF3A 3DSCA 1XM7A 3AV0A 4V0WA 1USHA 3DSDA 4H1SA 4O4KA 3FGAC 3THNA 5C1VA 4JA7A 2HY1A 4H2BA 1II7A 4ORAA 3AUZA 3K7VC 5DNYA 1S8EA 4ORBA 3E7BA 1KBPA 3DW8C 5IOHA 4FBWA 2P6BA 3QFNA 4O5GA 4H2IA 2IE3C 3PSOA 4MP0A 4IL1A 3H62B 3QFMA 2DFJA 4Q7FA 4KKZA 1OI8A 1WARA 4LACC 3T1IA 4LU9A 4F0ZA 2Q8UA 4FCXA 1TCOA 3RQZA 2AHDA 4ZX2A 3IB8A 2BQ8X 3ZTVA 2HYOA 1G5BA 4OR9A 4NZVA 5B8IA 5GTUA 5EQVA 4WWLA 2NPPC 2GJUA 4H2GA 2NXFA 2O8GA 4JA9A 4LTYA 3KBPA 3IB7A 4XPNA 3IVDA 1NNWA 3ICFA 3JYFA 3LL8A 4G9JA 3H68A 3H69A 3V4YA 1AUIA 3TGHA 1U32A 4O43A 4V0XA 2O8AA 3EGGA 1QHWA 4J6OA 2USHA 3QG5C 3EGHA 5JPEA 1XZWA 1Z2XA 1WAO1 4ORCA 1QFCA 2WDFA 3C5WC 1OIEA 1S70A 4FBQA 4B2OA 5JPFA 3E7AA 2NYMC 1HO5A 2QFRA 1V73A 3PSNA 3QFKA 3HVQA 2R17A 1JK7A 1S3NA 3RL4A 2Z06A 1T71A 2A22A 2WDCA 2ZBMA 4O24A 1S3LA 5F3WA 4YKEA 4UWQA 2WDEA 3H67A 1HPUA 1W24A 2IAEC 1M63A 1IT6A 4KBPA 4I5NC 2YVTA 3THOB 4UT2A 1T70A 3K7WC 3P71C 3RL3A 2CV9A 2QJCA 1OIDA 2JOGA 1MF8A 2BDXA 3H66A 2WDDA 5JJTA 3H63A 4FBKA 2IE4C 4ZVZA 4TUIA 2KKNA 2Z1AA 3C9FA
chains in the Genus database with same CATH superfamily
4I5LC 3CK2A 4IYPC 4M0VA 3GVEA 1FJMA 2BCDA 3H61A 3ZU0A 1UTEA 4MOYA 2HYPA 5J28A 3IVEA 1S95A 4DHLA 4UT3A 2QFPA 3H64A 4HD0A 4H1YP 2NYLC 4MOVA 4H2FA 4DT2A 2DXLA 4V0VA 4TUGA 3H60A 5INBA 2XMOA 1S3MA 1HP1A 5HPEA 1SU1A 4UT3B 1Z2WA 4DSYA 2Z72A 3QFOA 3N5UA 3RL5A 1UF3A 3DSCA 1XM7A 3AV0A 4V0WA 1USHA 3DSDA 4H1SA 4O4KA 3FGAC 3THNA 5C1VA 4JA7A 2HY1A 4H2BA 1II7A 4ORAA 3AUZA 3K7VC 5DNYA 1S8EA 4ORBA 3E7BA 1KBPA 3DW8C 5IOHA 4FBWA 2P6BA 3FLOA 3QFNA 4O5GA 4H2IA 2IE3C 3PSOA 4MP0A 4IL1A 3H62B 3QFMA 2DFJA 4Q7FA 4KKZA 1OI8A 1WARA 3E0JA 4LACC 3T1IA 4LU9A 4F0ZA 2Q8UA 4FCXA 1TCOA 3RQZA 2AHDA 4ZX2A 3IB8A 2BQ8X 3ZTVA 2HYOA 1G5BA 4OR9A 4NZVA 2ZO9B 5GTUA 5EQVA 4WWLA 2NPPC 5B8IA 2GJUA 4H2GA 2NXFA 2O8GA 4JA9A 4LTYA 3KBPA 3IB7A 3D03A 4XPNA 3IVDA 1NNWA 3ICFA 3JYFA 2ZOAA 3LL8A 4G9JA 3H68A 3H69A 3V4YA 1AUIA 3TGHA 1U32A 4O43A 4V0XA 2O8AA 3EGGA 1QHWA 4J6OA 2USHA 3QG5C 3EGHA 5JPEA 1XZWA 1Z2XA 1WAO1 4ORCA 1QFCA 2WDFA 3C5WC 1OIEA 1S70A 4FBQA 4B2OA 5JPFA 3E7AA 2NYMC 1HO5A 2QFRA 1V73A 2YEQA 3PSNA 3QFKA 3HVQA 2R17A 1JK7A 1S3NA 3RL4A 2Z06A 1T71A 2A22A 2WDCA 2ZBMA 4O24A 1S3LA 5F3WA 4YKEA 4UWQA 2WDEA 3H67A 1HPUA 1W24A 2IAEC 1M63A 1IT6A 4KBPA 4I5NC 2YVTA 3THOB 4UT2A 1T70A 3K7WC 2DXNA 3P71C 3RL3A 2CV9A 2QJCA 1OIDA 2JOGA 1MF8A 2BDXA 3H66A 2WDDA 5JJTA 3H63A 4FBKA 2IE4C 4ZVZA 4TUIA 2KKNA 2Z1AA 3C9FA
chains in the Genus database with same CATH topology
4I5LC 3CK2A 4IYPC 4M0VA 3GVEA 1FJMA 2BCDA 3H61A 3ZU0A 1UTEA 4MOYA 2HYPA 5J28A 3IVEA 1S95A 4DHLA 4UT3A 2QFPA 3H64A 4HD0A 4H1YP 2NYLC 4MOVA 4H2FA 4DT2A 2DXLA 4V0VA 4TUGA 3H60A 5INBA 2XMOA 1S3MA 1HP1A 5HPEA 1SU1A 4UT3B 1Z2WA 4DSYA 2Z72A 3QFOA 3N5UA 3RL5A 1UF3A 3DSCA 1XM7A 3AV0A 4V0WA 1USHA 3DSDA 4H1SA 4O4KA 3FGAC 3THNA 5C1VA 4JA7A 2HY1A 4H2BA 1II7A 4ORAA 3AUZA 3K7VC 5DNYA 1S8EA 4ORBA 3E7BA 1KBPA 3DW8C 5IOHA 4FBWA 2P6BA 3FLOA 3QFNA 4O5GA 4H2IA 2IE3C 3PSOA 4MP0A 4IL1A 3H62B 3QFMA 2DFJA 4Q7FA 4KKZA 1OI8A 1WARA 3E0JA 4LACC 3T1IA 4LU9A 4F0ZA 2Q8UA 4FCXA 1TCOA 3RQZA 2AHDA 4ZX2A 3IB8A 2BQ8X 3ZTVA 2HYOA 1G5BA 4OR9A 4NZVA 2ZO9B 5GTUA 5EQVA 4WWLA 2NPPC 5B8IA 2GJUA 4H2GA 2NXFA 2O8GA 4JA9A 4LTYA 3KBPA 3IB7A 3D03A 4XPNA 3IVDA 1NNWA 3ICFA 3JYFA 2ZOAA 3LL8A 4G9JA 3H68A 3H69A 3V4YA 1AUIA 3TGHA 1U32A 4O43A 4V0XA 2O8AA 3EGGA 1QHWA 4J6OA 2USHA 3QG5C 3EGHA 5JPEA 1XZWA 1Z2XA 1WAO1 4ORCA 1QFCA 2WDFA 3C5WC 1OIEA 1S70A 4FBQA 4B2OA 5JPFA 3E7AA 2NYMC 1HO5A 2QFRA 1V73A 2YEQA 3PSNA 3QFKA 3HVQA 2R17A 1JK7A 1S3NA 3RL4A 2Z06A 1T71A 2A22A 2WDCA 2ZBMA 4O24A 1S3LA 5F3WA 4YKEA 4UWQA 2WDEA 3H67A 1HPUA 1W24A 2IAEC 1M63A 1IT6A 4KBPA 4I5NC 2YVTA 3THOB 4UT2A 1T70A 3K7WC 2DXNA 3P71C 3RL3A 2CV9A 2QJCA 1OIDA 2JOGA 1MF8A 2BDXA 3H66A 2WDDA 5JJTA 3H63A 4FBKA 2IE4C 4ZVZA 4TUIA 2KKNA 2Z1AA 3C9FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I5L C;  3CK2 A;  4IYP C;  4M0V A;  3GVE A;  1FJM A;  2BCD A;  3H61 A;  3ZU0 A;  1UTE A;  4MOY A;  2HYP A;  5J28 A;  3IVE A;  1S95 A;  4DHL A;  4UT3 A;  2QFP A;  3H64 A;  4HD0 A;  4H1Y P;  2NYL C;  4MOV A;  4H2F A;  4DT2 A;  4V0V A;  4TUG A;  3H60 A;  5INB A;  2XMO A;  1S3M A;  1HP1 A;  5HPE A;  1SU1 A;  4UT3 B;  1Z2W A;  4DSY A;  2Z72 A;  3QFO A;  3N5U A;  3RL5 A;  1UF3 A;  3DSC A;  1XM7 A;  3AV0 A;  4V0W A;  1USH A;  3DSD A;  4H1S A;  4O4K A;  3FGA C;  3THN A;  5C1V A;  4JA7 A;  2HY1 A;  4H2B A;  1II7 A;  4ORA A;  3AUZ A;  3K7V C;  5DNY A;  1S8E A;  4ORB A;  3E7B A;  1KBP A;  3DW8 C;  5IOH A;  4FBW A;  2P6B A;  3QFN A;  4O5G A;  4H2I A;  2IE3 C;  3PSO A;  4MP0 A;  4IL1 A;  3H62 B;  3QFM A;  2DFJ A;  4Q7F A;  4KKZ A;  1OI8 A;  1WAR A;  4LAC C;  3T1I A;  4LU9 A;  4F0Z A;  2Q8U A;  4FCX A;  1TCO A;  3RQZ A;  2AHD A;  4ZX2 A;  3IB8 A;  2BQ8 X;  3ZTV A;  2HYO A;  1G5B A;  4OR9 A;  4NZV A;  5B8I A;  5GTU A;  5EQV A;  4WWL A;  2NPP C;  2GJU A;  4H2G A;  2NXF A;  2O8G A;  4JA9 A;  4LTY A;  3KBP A;  3IB7 A;  4XPN A;  3IVD A;  1NNW A;  3ICF A;  3JYF A;  3LL8 A;  4G9J A;  3H68 A;  3H69 A;  3V4Y A;  1AUI A;  3TGH A;  1U32 A;  4O43 A;  4V0X A;  2O8A A;  3EGG A;  1QHW A;  4J6O A;  2USH A;  3QG5 C;  3EGH A;  5JPE A;  1XZW A;  1Z2X A;  1WAO 1;  4ORC A;  1QFC A;  2WDF A;  3C5W C;  1OIE A;  1S70 A;  4FBQ A;  4B2O A;  5JPF A;  3E7A A;  2NYM C;  1HO5 A;  2QFR A;  1V73 A;  3PSN A;  3QFK A;  3HVQ A;  2R17 A;  1JK7 A;  1S3N A;  3RL4 A;  2Z06 A;  1T71 A;  2A22 A;  2WDC A;  2ZBM A;  4O24 A;  1S3L A;  5F3W A;  4YKE A;  4UWQ A;  2WDE A;  3H67 A;  1HPU A;  1W24 A;  2IAE C;  1M63 A;  1IT6 A;  4KBP A;  4I5N C;  2YVT A;  3THO B;  4UT2 A;  1T70 A;  3K7W C;  3P71 C;  3RL3 A;  2CV9 A;  2QJC A;  1OID A;  2JOG A;  1MF8 A;  2BDX A;  3H66 A;  2WDD A;  5JJT A;  3H63 A;  4FBK A;  2IE4 C;  4ZVZ A;  4TUI A;  2KKN A;  2Z1A A;  3C9F A; 
#chains in the Genus database with same CATH topology
 4I5L C;  3CK2 A;  4IYP C;  4M0V A;  3GVE A;  1FJM A;  2BCD A;  3H61 A;  3ZU0 A;  1UTE A;  4MOY A;  2HYP A;  5J28 A;  3IVE A;  1S95 A;  4DHL A;  4UT3 A;  2QFP A;  3H64 A;  4HD0 A;  4H1Y P;  2NYL C;  4MOV A;  4H2F A;  4DT2 A;  2DXL A;  4V0V A;  4TUG A;  3H60 A;  5INB A;  2XMO A;  1S3M A;  1HP1 A;  5HPE A;  1SU1 A;  4UT3 B;  1Z2W A;  4DSY A;  2Z72 A;  3QFO A;  3N5U A;  3RL5 A;  1UF3 A;  3DSC A;  1XM7 A;  3AV0 A;  4V0W A;  1USH A;  3DSD A;  4H1S A;  4O4K A;  3FGA C;  3THN A;  5C1V A;  4JA7 A;  2HY1 A;  4H2B A;  1II7 A;  4ORA A;  3AUZ A;  3K7V C;  5DNY A;  1S8E A;  4ORB A;  3E7B A;  1KBP A;  3DW8 C;  5IOH A;  4FBW A;  2P6B A;  3FLO A;  3QFN A;  4O5G A;  4H2I A;  2IE3 C;  3PSO A;  4MP0 A;  4IL1 A;  3H62 B;  3QFM A;  2DFJ A;  4Q7F A;  4KKZ A;  1OI8 A;  1WAR A;  3E0J A;  4LAC C;  3T1I A;  4LU9 A;  4F0Z A;  2Q8U A;  4FCX A;  1TCO A;  3RQZ A;  2AHD A;  4ZX2 A;  3IB8 A;  2BQ8 X;  3ZTV A;  2HYO A;  1G5B A;  4OR9 A;  4NZV A;  2ZO9 B;  5GTU A;  5EQV A;  4WWL A;  2NPP C;  5B8I A;  2GJU A;  4H2G A;  2NXF A;  2O8G A;  4JA9 A;  4LTY A;  3KBP A;  3IB7 A;  3D03 A;  4XPN A;  3IVD A;  1NNW A;  3ICF A;  3JYF A;  2ZOA A;  3LL8 A;  4G9J A;  3H68 A;  3H69 A;  3V4Y A;  1AUI A;  3TGH A;  1U32 A;  4O43 A;  4V0X A;  2O8A A;  3EGG A;  1QHW A;  4J6O A;  2USH A;  3QG5 C;  3EGH A;  5JPE A;  1XZW A;  1Z2X A;  1WAO 1;  4ORC A;  1QFC A;  2WDF A;  3C5W C;  1OIE A;  1S70 A;  4FBQ A;  4B2O A;  5JPF A;  3E7A A;  2NYM C;  1HO5 A;  2QFR A;  1V73 A;  2YEQ A;  3PSN A;  3QFK A;  3HVQ A;  2R17 A;  1JK7 A;  1S3N A;  3RL4 A;  2Z06 A;  1T71 A;  2A22 A;  2WDC A;  2ZBM A;  4O24 A;  1S3L A;  5F3W A;  4YKE A;  4UWQ A;  2WDE A;  3H67 A;  1HPU A;  1W24 A;  2IAE C;  1M63 A;  1IT6 A;  4KBP A;  4I5N C;  2YVT A;  3THO B;  4UT2 A;  1T70 A;  3K7W C;  2DXN A;  3P71 C;  3RL3 A;  2CV9 A;  2QJC A;  1OID A;  2JOG A;  1MF8 A;  2BDX A;  3H66 A;  2WDD A;  5JJT A;  3H63 A;  4FBK A;  2IE4 C;  4ZVZ A;  4TUI A;  2KKN A;  2Z1A A;  3C9F A; 
#chains in the Genus database with same CATH homology
 4I5L C;  3CK2 A;  4IYP C;  4M0V A;  3GVE A;  1FJM A;  2BCD A;  3H61 A;  3ZU0 A;  1UTE A;  4MOY A;  2HYP A;  5J28 A;  3IVE A;  1S95 A;  4DHL A;  4UT3 A;  2QFP A;  3H64 A;  4HD0 A;  4H1Y P;  2NYL C;  4MOV A;  4H2F A;  4DT2 A;  2DXL A;  4V0V A;  4TUG A;  3H60 A;  5INB A;  2XMO A;  1S3M A;  1HP1 A;  5HPE A;  1SU1 A;  4UT3 B;  1Z2W A;  4DSY A;  2Z72 A;  3QFO A;  3N5U A;  3RL5 A;  1UF3 A;  3DSC A;  1XM7 A;  3AV0 A;  4V0W A;  1USH A;  3DSD A;  4H1S A;  4O4K A;  3FGA C;  3THN A;  5C1V A;  4JA7 A;  2HY1 A;  4H2B A;  1II7 A;  4ORA A;  3AUZ A;  3K7V C;  5DNY A;  1S8E A;  4ORB A;  3E7B A;  1KBP A;  3DW8 C;  5IOH A;  4FBW A;  2P6B A;  3FLO A;  3QFN A;  4O5G A;  4H2I A;  2IE3 C;  3PSO A;  4MP0 A;  4IL1 A;  3H62 B;  3QFM A;  2DFJ A;  4Q7F A;  4KKZ A;  1OI8 A;  1WAR A;  3E0J A;  4LAC C;  3T1I A;  4LU9 A;  4F0Z A;  2Q8U A;  4FCX A;  1TCO A;  3RQZ A;  2AHD A;  4ZX2 A;  3IB8 A;  2BQ8 X;  3ZTV A;  2HYO A;  1G5B A;  4OR9 A;  4NZV A;  2ZO9 B;  5GTU A;  5EQV A;  4WWL A;  2NPP C;  5B8I A;  2GJU A;  4H2G A;  2NXF A;  2O8G A;  4JA9 A;  4LTY A;  3KBP A;  3IB7 A;  3D03 A;  4XPN A;  3IVD A;  1NNW A;  3ICF A;  3JYF A;  2ZOA A;  3LL8 A;  4G9J A;  3H68 A;  3H69 A;  3V4Y A;  1AUI A;  3TGH A;  1U32 A;  4O43 A;  4V0X A;  2O8A A;  3EGG A;  1QHW A;  4J6O A;  2USH A;  3QG5 C;  3EGH A;  5JPE A;  1XZW A;  1Z2X A;  1WAO 1;  4ORC A;  1QFC A;  2WDF A;  3C5W C;  1OIE A;  1S70 A;  4FBQ A;  4B2O A;  5JPF A;  3E7A A;  2NYM C;  1HO5 A;  2QFR A;  1V73 A;  2YEQ A;  3PSN A;  3QFK A;  3HVQ A;  2R17 A;  1JK7 A;  1S3N A;  3RL4 A;  2Z06 A;  1T71 A;  2A22 A;  2WDC A;  2ZBM A;  4O24 A;  1S3L A;  5F3W A;  4YKE A;  4UWQ A;  2WDE A;  3H67 A;  1HPU A;  1W24 A;  2IAE C;  1M63 A;  1IT6 A;  4KBP A;  4I5N C;  2YVT A;  3THO B;  4UT2 A;  1T70 A;  3K7W C;  2DXN A;  3P71 C;  3RL3 A;  2CV9 A;  2QJC A;  1OID A;  2JOG A;  1MF8 A;  2BDX A;  3H66 A;  2WDD A;  5JJT A;  3H63 A;  4FBK A;  2IE4 C;  4ZVZ A;  4TUI A;  2KKN A;  2Z1A A;  3C9F A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...