3JYFA

The crystal structure of a 2,3-cyclic nucleotide 2-phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor protein from klebsiella pneumoniae subsp. pneumoniae mgh 78578
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
336
structure length
336
Chain Sequence
AATVDLRIMETTDLHSNMMDFDYYKDAATEKFGLVRTASLIEQARAEVKNSVLVDNGDVIQGSPLGDYMAAKGLKEGDVHPVYKAMNTLNYAVGNLGNHEFNYGLDFLHKALAGAKFPYVNANIIDAKTGKPMFTPYLIQDTRVVDSDGQIHTLRIGYIGFVPPQIMTWDKANLNGKVTVNDITETARKYIPEMRAKGADVVVVVAHSGLSADPYQAMAENSVYYLSQVPGVDAIMFGHAHAVFPGKDFANIKGADIAKGTLNGVPAVMPGMWGDHLGVVDLVLNNDSGKWQVTQSKAEARPIYDAVAKKSLAAEDGKLVSVLKADHDATREFVSK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of a 2,3-cyclic nucleotide 2-phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor protein from Klebsiella pneumoniae subsp. pneumoniae MGH 78578
rcsb
molecule tags Hydrolase
source organism Klebsiella pneumoniae subsp. pneumoniae
molecule keywords 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase
total genus 91
structure length 336
sequence length 336
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-09-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3jyfA00
3AUZA 1S3MA 5IOHA 2Q8UA 3QFNA 5GTUA 1WAO1 4M0VA 3RL5A 2IE3C 5DNYA 5HPEA 1TCOA 1Z2XA 4ZVZA 2BCDA 1HPUA 3H64A 4V0WA 4V0VA 4DSYA 1S70A 2GJUA 4UT2A 1KBPA 4MOVA 4UT3B 3RL3A 3CK2A 3IB8A 5INBA 4XPNA 4OR9A 2AHDA 3C9FA 3K7VC 3IB7A 3ZU0A 3E7AA 3H61A 3DSCA 4KBPA 4DHLA 4LU9A 4FBWA 3THOB 3H69A 4H1SA 3IVEA 3HVQA 4JA7A 4LACC 3LL8A 3KBPA 3QFOA 4FCXA 4O5GA 3E7BA 2IE4C 1Z2WA 2QJCA 3RL4A 3FGAC 1XZWA 3H67A 3TGHA 3GVEA 3N5UA 3PSNA 3H66A 4TUGA 4G9JA 2USHA 1IT6A 2HYOA 3DW8C 2QFPA 1S95A 4WWLA 3THNA 3K7WC 4O4KA 4ORBA 3ICFA 4V0XA 4F0ZA 4JA9A 3QFKA 2QFRA 1S3NA 1G5BA 3QFMA 4H1YP 4MP0A 2A22A 4Q7FA 3DSDA 5J28A 4O24A 2XMOA 4H2GA 2NYLC 2BDXA 1QHWA 1QFCA 2KKNA 1HO5A 4O43A 2HYPA 2WDCA 3EGHA 1II7A 2WDFA 4YKEA 3EGGA 1M63A 4DT2A 1OIDA 1T70A 4LTYA 3IVDA 4MOYA 2HY1A 1S3LA 1U32A 2IAEC 3T1IA 4H2IA 1AUIA 1SU1A 2YVTA 4UWQA 1XM7A 2ZBMA 1JK7A 3RQZA 4H2FA 5EQVA 5B8IA 3P71C 1HP1A 1OI8A 4ORAA 3ZTVA 3H60A 2JOGA 2R17A 1V73A 2NPPC 4FBQA 4TUIA 1USHA 4I5LC 2CV9A 1OIEA 4ZX2A 3QG5C 3V4YA 4I5NC 2P6BA 2BQ8X 4IYPC 4H2BA 3AV0A 5JPFA 1UF3A 2Z1AA 1WARA 4HD0A 2DFJA 5JJTA 3PSOA 2WDEA 2WDDA 4NZVA 3C5WC 1UTEA 1W24A 4ORCA 1FJMA 2Z06A 1NNWA 2NXFA 1T71A 3JYFA 4IL1A 4UT3A 5C1VA 4B2OA 4FBKA 4J6OA 4KKZA 5JPEA 2NYMC 3H68A 1S8EA 3H63A 5F3WA 2O8AA 3H62B 2Z72A 2O8GA 1MF8A
chains in the Genus database with same CATH superfamily
3AUZA 1S3MA 5IOHA 2Q8UA 3QFNA 5GTUA 1WAO1 2DXLA 4M0VA 3RL5A 2IE3C 5DNYA 5HPEA 1TCOA 1Z2XA 3D03A 4ZVZA 2BCDA 1HPUA 3H64A 4V0WA 4V0VA 4DSYA 1S70A 2GJUA 4UT2A 1KBPA 4MOVA 4UT3B 3RL3A 3CK2A 3IB8A 5INBA 2DXNA 4XPNA 4OR9A 2AHDA 3C9FA 3K7VC 3IB7A 3ZU0A 3E7AA 3H61A 3DSCA 4KBPA 4DHLA 4LU9A 4FBWA 3THOB 3H69A 4H1SA 3IVEA 3HVQA 4JA7A 4LACC 3LL8A 3KBPA 3QFOA 4FCXA 4O5GA 3E7BA 2IE4C 1Z2WA 2QJCA 3RL4A 3FGAC 1XZWA 3H67A 3TGHA 3GVEA 3N5UA 3PSNA 3H66A 4TUGA 4G9JA 2USHA 1IT6A 2HYOA 3DW8C 2QFPA 1S95A 4WWLA 3E0JA 3THNA 3K7WC 4O4KA 4ORBA 3ICFA 4V0XA 4F0ZA 4JA9A 3QFKA 2QFRA 1S3NA 1G5BA 3QFMA 4H1YP 4MP0A 2A22A 4Q7FA 3DSDA 5J28A 4O24A 2XMOA 4H2GA 2NYLC 2BDXA 2ZO9B 1QHWA 1QFCA 2KKNA 1HO5A 4O43A 2HYPA 2WDCA 3EGHA 1II7A 2WDFA 4YKEA 3EGGA 1M63A 4DT2A 1OIDA 1T70A 4LTYA 3IVDA 4MOYA 2HY1A 1S3LA 1U32A 2IAEC 3T1IA 4H2IA 1AUIA 1SU1A 2YVTA 2ZOAA 4UWQA 1XM7A 2ZBMA 1JK7A 3RQZA 4H2FA 5EQVA 5B8IA 2YEQA 3P71C 1HP1A 1OI8A 4ORAA 3ZTVA 3H60A 2JOGA 2R17A 1V73A 2NPPC 4FBQA 4TUIA 1USHA 4I5LC 2CV9A 1OIEA 4ZX2A 3QG5C 3V4YA 4I5NC 3FLOA 2P6BA 2BQ8X 4IYPC 4H2BA 3AV0A 5JPFA 1UF3A 2Z1AA 1WARA 4HD0A 2DFJA 5JJTA 3PSOA 2WDEA 2WDDA 4NZVA 3C5WC 1UTEA 1W24A 4ORCA 1FJMA 2Z06A 1NNWA 2NXFA 1T71A 3JYFA 4IL1A 4UT3A 5C1VA 4B2OA 4FBKA 4J6OA 4KKZA 5JPEA 2NYMC 3H68A 1S8EA 3H63A 5F3WA 2O8AA 3H62B 2Z72A 2O8GA 1MF8A
chains in the Genus database with same CATH topology
3AUZA 1S3MA 5IOHA 2Q8UA 3QFNA 5GTUA 1WAO1 2DXLA 4M0VA 3RL5A 2IE3C 5DNYA 5HPEA 1TCOA 1Z2XA 3D03A 4ZVZA 2BCDA 1HPUA 3H64A 4V0WA 4V0VA 4DSYA 1S70A 2GJUA 4UT2A 1KBPA 4MOVA 4UT3B 3RL3A 3CK2A 3IB8A 5INBA 2DXNA 4XPNA 4OR9A 2AHDA 3C9FA 3K7VC 3IB7A 3ZU0A 3E7AA 3H61A 3DSCA 4KBPA 4DHLA 4LU9A 4FBWA 3THOB 3H69A 4H1SA 3IVEA 3HVQA 4JA7A 4LACC 3LL8A 3KBPA 3QFOA 4FCXA 4O5GA 3E7BA 2IE4C 1Z2WA 2QJCA 3RL4A 3FGAC 1XZWA 3H67A 3TGHA 3GVEA 3N5UA 3PSNA 3H66A 4TUGA 4G9JA 2USHA 1IT6A 2HYOA 3DW8C 2QFPA 1S95A 4WWLA 3E0JA 3THNA 3K7WC 4O4KA 4ORBA 3ICFA 4V0XA 4F0ZA 4JA9A 3QFKA 2QFRA 1S3NA 1G5BA 3QFMA 4H1YP 4MP0A 2A22A 4Q7FA 3DSDA 5J28A 4O24A 2XMOA 4H2GA 2NYLC 2BDXA 2ZO9B 1QHWA 1QFCA 2KKNA 1HO5A 4O43A 2HYPA 2WDCA 3EGHA 1II7A 2WDFA 4YKEA 3EGGA 1M63A 4DT2A 1OIDA 1T70A 4LTYA 3IVDA 4MOYA 2HY1A 1S3LA 1U32A 2IAEC 3T1IA 4H2IA 1AUIA 1SU1A 2YVTA 2ZOAA 4UWQA 1XM7A 2ZBMA 1JK7A 3RQZA 4H2FA 5EQVA 5B8IA 2YEQA 3P71C 1HP1A 1OI8A 4ORAA 3ZTVA 3H60A 2JOGA 2R17A 1V73A 2NPPC 4FBQA 4TUIA 1USHA 4I5LC 2CV9A 1OIEA 4ZX2A 3QG5C 3V4YA 4I5NC 3FLOA 2P6BA 2BQ8X 4IYPC 4H2BA 3AV0A 5JPFA 1UF3A 2Z1AA 1WARA 4HD0A 2DFJA 5JJTA 3PSOA 2WDEA 2WDDA 4NZVA 3C5WC 1UTEA 1W24A 4ORCA 1FJMA 2Z06A 1NNWA 2NXFA 1T71A 3JYFA 4IL1A 4UT3A 5C1VA 4B2OA 4FBKA 4J6OA 4KKZA 5JPEA 2NYMC 3H68A 1S8EA 3H63A 5F3WA 2O8AA 3H62B 2Z72A 2O8GA 1MF8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AUZ A;  1S3M A;  5IOH A;  2Q8U A;  3QFN A;  5GTU A;  1WAO 1;  4M0V A;  3RL5 A;  2IE3 C;  5DNY A;  5HPE A;  1TCO A;  1Z2X A;  4ZVZ A;  2BCD A;  1HPU A;  3H64 A;  4V0W A;  4V0V A;  4DSY A;  1S70 A;  2GJU A;  4UT2 A;  1KBP A;  4MOV A;  4UT3 B;  3RL3 A;  3CK2 A;  3IB8 A;  5INB A;  4XPN A;  4OR9 A;  2AHD A;  3C9F A;  3K7V C;  3IB7 A;  3ZU0 A;  3E7A A;  3H61 A;  3DSC A;  4KBP A;  4DHL A;  4LU9 A;  4FBW A;  3THO B;  3H69 A;  4H1S A;  3IVE A;  3HVQ A;  4JA7 A;  4LAC C;  3LL8 A;  3KBP A;  3QFO A;  4FCX A;  4O5G A;  3E7B A;  2IE4 C;  1Z2W A;  2QJC A;  3RL4 A;  3FGA C;  1XZW A;  3H67 A;  3TGH A;  3GVE A;  3N5U A;  3PSN A;  3H66 A;  4TUG A;  4G9J A;  2USH A;  1IT6 A;  2HYO A;  3DW8 C;  2QFP A;  1S95 A;  4WWL A;  3THN A;  3K7W C;  4O4K A;  4ORB A;  3ICF A;  4V0X A;  4F0Z A;  4JA9 A;  3QFK A;  2QFR A;  1S3N A;  1G5B A;  3QFM A;  4H1Y P;  4MP0 A;  2A22 A;  4Q7F A;  3DSD A;  5J28 A;  4O24 A;  2XMO A;  4H2G A;  2NYL C;  2BDX A;  1QHW A;  1QFC A;  2KKN A;  1HO5 A;  4O43 A;  2HYP A;  2WDC A;  3EGH A;  1II7 A;  2WDF A;  4YKE A;  3EGG A;  1M63 A;  4DT2 A;  1OID A;  1T70 A;  4LTY A;  3IVD A;  4MOY A;  2HY1 A;  1S3L A;  1U32 A;  2IAE C;  3T1I A;  4H2I A;  1AUI A;  1SU1 A;  2YVT A;  4UWQ A;  1XM7 A;  2ZBM A;  1JK7 A;  3RQZ A;  4H2F A;  5EQV A;  5B8I A;  3P71 C;  1HP1 A;  1OI8 A;  4ORA A;  3ZTV A;  3H60 A;  2JOG A;  2R17 A;  1V73 A;  2NPP C;  4FBQ A;  4TUI A;  1USH A;  4I5L C;  2CV9 A;  1OIE A;  4ZX2 A;  3QG5 C;  3V4Y A;  4I5N C;  2P6B A;  2BQ8 X;  4IYP C;  4H2B A;  3AV0 A;  5JPF A;  1UF3 A;  2Z1A A;  1WAR A;  4HD0 A;  2DFJ A;  5JJT A;  3PSO A;  2WDE A;  2WDD A;  4NZV A;  3C5W C;  1UTE A;  1W24 A;  4ORC A;  1FJM A;  2Z06 A;  1NNW A;  2NXF A;  1T71 A;  3JYF A;  4IL1 A;  4UT3 A;  5C1V A;  4B2O A;  4FBK A;  4J6O A;  4KKZ A;  5JPE A;  2NYM C;  3H68 A;  1S8E A;  3H63 A;  5F3W A;  2O8A A;  3H62 B;  2Z72 A;  2O8G A;  1MF8 A; 
#chains in the Genus database with same CATH topology
 3AUZ A;  1S3M A;  5IOH A;  2Q8U A;  3QFN A;  5GTU A;  1WAO 1;  2DXL A;  4M0V A;  3RL5 A;  2IE3 C;  5DNY A;  5HPE A;  1TCO A;  1Z2X A;  3D03 A;  4ZVZ A;  2BCD A;  1HPU A;  3H64 A;  4V0W A;  4V0V A;  4DSY A;  1S70 A;  2GJU A;  4UT2 A;  1KBP A;  4MOV A;  4UT3 B;  3RL3 A;  3CK2 A;  3IB8 A;  5INB A;  2DXN A;  4XPN A;  4OR9 A;  2AHD A;  3C9F A;  3K7V C;  3IB7 A;  3ZU0 A;  3E7A A;  3H61 A;  3DSC A;  4KBP A;  4DHL A;  4LU9 A;  4FBW A;  3THO B;  3H69 A;  4H1S A;  3IVE A;  3HVQ A;  4JA7 A;  4LAC C;  3LL8 A;  3KBP A;  3QFO A;  4FCX A;  4O5G A;  3E7B A;  2IE4 C;  1Z2W A;  2QJC A;  3RL4 A;  3FGA C;  1XZW A;  3H67 A;  3TGH A;  3GVE A;  3N5U A;  3PSN A;  3H66 A;  4TUG A;  4G9J A;  2USH A;  1IT6 A;  2HYO A;  3DW8 C;  2QFP A;  1S95 A;  4WWL A;  3E0J A;  3THN A;  3K7W C;  4O4K A;  4ORB A;  3ICF A;  4V0X A;  4F0Z A;  4JA9 A;  3QFK A;  2QFR A;  1S3N A;  1G5B A;  3QFM A;  4H1Y P;  4MP0 A;  2A22 A;  4Q7F A;  3DSD A;  5J28 A;  4O24 A;  2XMO A;  4H2G A;  2NYL C;  2BDX A;  2ZO9 B;  1QHW A;  1QFC A;  2KKN A;  1HO5 A;  4O43 A;  2HYP A;  2WDC A;  3EGH A;  1II7 A;  2WDF A;  4YKE A;  3EGG A;  1M63 A;  4DT2 A;  1OID A;  1T70 A;  4LTY A;  3IVD A;  4MOY A;  2HY1 A;  1S3L A;  1U32 A;  2IAE C;  3T1I A;  4H2I A;  1AUI A;  1SU1 A;  2YVT A;  2ZOA A;  4UWQ A;  1XM7 A;  2ZBM A;  1JK7 A;  3RQZ A;  4H2F A;  5EQV A;  5B8I A;  2YEQ A;  3P71 C;  1HP1 A;  1OI8 A;  4ORA A;  3ZTV A;  3H60 A;  2JOG A;  2R17 A;  1V73 A;  2NPP C;  4FBQ A;  4TUI A;  1USH A;  4I5L C;  2CV9 A;  1OIE A;  4ZX2 A;  3QG5 C;  3V4Y A;  4I5N C;  3FLO A;  2P6B A;  2BQ8 X;  4IYP C;  4H2B A;  3AV0 A;  5JPF A;  1UF3 A;  2Z1A A;  1WAR A;  4HD0 A;  2DFJ A;  5JJT A;  3PSO A;  2WDE A;  2WDD A;  4NZV A;  3C5W C;  1UTE A;  1W24 A;  4ORC A;  1FJM A;  2Z06 A;  1NNW A;  2NXF A;  1T71 A;  3JYF A;  4IL1 A;  4UT3 A;  5C1V A;  4B2O A;  4FBK A;  4J6O A;  4KKZ A;  5JPE A;  2NYM C;  3H68 A;  1S8E A;  3H63 A;  5F3W A;  2O8A A;  3H62 B;  2Z72 A;  2O8G A;  1MF8 A; 
#chains in the Genus database with same CATH homology
 3AUZ A;  1S3M A;  5IOH A;  2Q8U A;  3QFN A;  5GTU A;  1WAO 1;  2DXL A;  4M0V A;  3RL5 A;  2IE3 C;  5DNY A;  5HPE A;  1TCO A;  1Z2X A;  3D03 A;  4ZVZ A;  2BCD A;  1HPU A;  3H64 A;  4V0W A;  4V0V A;  4DSY A;  1S70 A;  2GJU A;  4UT2 A;  1KBP A;  4MOV A;  4UT3 B;  3RL3 A;  3CK2 A;  3IB8 A;  5INB A;  2DXN A;  4XPN A;  4OR9 A;  2AHD A;  3C9F A;  3K7V C;  3IB7 A;  3ZU0 A;  3E7A A;  3H61 A;  3DSC A;  4KBP A;  4DHL A;  4LU9 A;  4FBW A;  3THO B;  3H69 A;  4H1S A;  3IVE A;  3HVQ A;  4JA7 A;  4LAC C;  3LL8 A;  3KBP A;  3QFO A;  4FCX A;  4O5G A;  3E7B A;  2IE4 C;  1Z2W A;  2QJC A;  3RL4 A;  3FGA C;  1XZW A;  3H67 A;  3TGH A;  3GVE A;  3N5U A;  3PSN A;  3H66 A;  4TUG A;  4G9J A;  2USH A;  1IT6 A;  2HYO A;  3DW8 C;  2QFP A;  1S95 A;  4WWL A;  3E0J A;  3THN A;  3K7W C;  4O4K A;  4ORB A;  3ICF A;  4V0X A;  4F0Z A;  4JA9 A;  3QFK A;  2QFR A;  1S3N A;  1G5B A;  3QFM A;  4H1Y P;  4MP0 A;  2A22 A;  4Q7F A;  3DSD A;  5J28 A;  4O24 A;  2XMO A;  4H2G A;  2NYL C;  2BDX A;  2ZO9 B;  1QHW A;  1QFC A;  2KKN A;  1HO5 A;  4O43 A;  2HYP A;  2WDC A;  3EGH A;  1II7 A;  2WDF A;  4YKE A;  3EGG A;  1M63 A;  4DT2 A;  1OID A;  1T70 A;  4LTY A;  3IVD A;  4MOY A;  2HY1 A;  1S3L A;  1U32 A;  2IAE C;  3T1I A;  4H2I A;  1AUI A;  1SU1 A;  2YVT A;  2ZOA A;  4UWQ A;  1XM7 A;  2ZBM A;  1JK7 A;  3RQZ A;  4H2F A;  5EQV A;  5B8I A;  2YEQ A;  3P71 C;  1HP1 A;  1OI8 A;  4ORA A;  3ZTV A;  3H60 A;  2JOG A;  2R17 A;  1V73 A;  2NPP C;  4FBQ A;  4TUI A;  1USH A;  4I5L C;  2CV9 A;  1OIE A;  4ZX2 A;  3QG5 C;  3V4Y A;  4I5N C;  3FLO A;  2P6B A;  2BQ8 X;  4IYP C;  4H2B A;  3AV0 A;  5JPF A;  1UF3 A;  2Z1A A;  1WAR A;  4HD0 A;  2DFJ A;  5JJT A;  3PSO A;  2WDE A;  2WDD A;  4NZV A;  3C5W C;  1UTE A;  1W24 A;  4ORC A;  1FJM A;  2Z06 A;  1NNW A;  2NXF A;  1T71 A;  3JYF A;  4IL1 A;  4UT3 A;  5C1V A;  4B2O A;  4FBK A;  4J6O A;  4KKZ A;  5JPE A;  2NYM C;  3H68 A;  1S8E A;  3H63 A;  5F3W A;  2O8A A;  3H62 B;  2Z72 A;  2O8G A;  1MF8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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