3LL8A

Crystal structure of calcineurin in complex with akap79 peptide
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
357
structure length
357
Chain Sequence
TDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)-calcineurin-NFAT signaling.
pubmed doi rcsb
molecule tags Hydrolase/calcium binding protein
source organism Homo sapiens
molecule keywords AKAP79 peptide
total genus 126
structure length 357
sequence length 357
chains with identical sequence C
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2010-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3ll8A00
1SU1A 2NPPC 4FCXA 3ICFA 4H2IA 2O8AA 1USHA 3ZU0A 3K7VC 4G9JA 5INBA 4FBKA 3HVQA 1MF8A 2BCDA 3AV0A 2BQ8X 1QFCA 1HPUA 1T70A 1Z2XA 1S8EA 4UT3B 3C9FA 5J28A 1W24A 1IT6A 3CK2A 4V0WA 5GTUA 4WWLA 4IYPC 1T71A 5C1VA 2IE4C 4TUGA 1OIDA 2A22A 1HO5A 2O8GA 3H60A 2QJCA 5HPEA 2WDEA 1U32A 3DSDA 4DHLA 2AHDA 4HD0A 1TCOA 1II7A 4H1SA 4TUIA 1M63A 4H2GA 3TGHA 4V0VA 3RL4A 3H68A 4DSYA 1HP1A 1KBPA 1S3MA 3RQZA 4ORCA 2QFRA 2R17A 1UF3A 4O4KA 4ZX2A 2Q8UA 2Z06A 4KBPA 4UT3A 3IVDA 4LTYA 1S3NA 3THOB 4MOYA 2Z1AA 1Z2WA 3PSNA 4LACC 3QG5C 3QFNA 4H2BA 3DSCA 2HY1A 4JA9A 1S70A 4O24A 3ZTVA 4B2OA 4MOVA 4FBQA 2QFPA 2NYLC 3H66A 3E7AA 2IAEC 2ZBMA 3H63A 4J6OA 4IL1A 4MP0A 3DW8C 5B8IA 3N5UA 4I5LC 3THNA 3H61A 3H64A 2WDDA 3KBPA 4ORBA 3QFMA 3FGAC 4M0VA 4XPNA 3EGHA 3QFKA 3PSOA 2HYPA 4O43A 4Q7FA 1S95A 1NNWA 2DFJA 3T1IA 1S3LA 3C5WC 4KKZA 2USHA 4UWQA 1OIEA 1JK7A 2CV9A 4UT2A 4V0XA 3QFOA 3H62B 1OI8A 3RL5A 5JJTA 2WDFA 2KKNA 1V73A 1AUIA 4H1YP 5DNYA 3IB7A 2YVTA 2IE3C 4H2FA 3EGGA 4LU9A 3H67A 4O5GA 1QHWA 4NZVA 1FJMA 3AUZA 4ORAA 1WARA 4I5NC 3RL3A 2GJUA 3P71C 2NXFA 5F3WA 3H69A 1UTEA 5EQVA 4F0ZA 1WAO1 4YKEA 3V4YA 2Z72A 2BDXA 3LL8A 3K7WC 3IVEA 4ZVZA 1G5BA 1XZWA 2P6BA 5JPFA 2HYOA 3GVEA 2NYMC 4DT2A 4JA7A 1XM7A 2XMOA 5JPEA 2WDCA 3JYFA 3E7BA 4FBWA 2JOGA 5IOHA 3IB8A 4OR9A
chains in the Genus database with same CATH superfamily
1SU1A 2NPPC 4FCXA 3ICFA 4H2IA 2ZOAA 2O8AA 1USHA 3ZU0A 3K7VC 4G9JA 5INBA 4FBKA 3HVQA 1MF8A 2BCDA 3AV0A 2BQ8X 1QFCA 1HPUA 1T70A 1Z2XA 1S8EA 4UT3B 3C9FA 5J28A 1W24A 1IT6A 3CK2A 4V0WA 5GTUA 4WWLA 4IYPC 1T71A 5C1VA 2IE4C 4TUGA 1OIDA 2A22A 1HO5A 2O8GA 3H60A 2QJCA 5HPEA 2WDEA 1U32A 3DSDA 4DHLA 2AHDA 4HD0A 1TCOA 1II7A 4H1SA 4TUIA 1M63A 4H2GA 3TGHA 4V0VA 3FLOA 3RL4A 3H68A 4DSYA 1HP1A 1KBPA 1S3MA 3RQZA 4ORCA 2QFRA 2R17A 1UF3A 4O4KA 4ZX2A 2Q8UA 2Z06A 4KBPA 4UT3A 3IVDA 4LTYA 1S3NA 3THOB 4MOYA 2Z1AA 1Z2WA 3PSNA 2ZO9B 4LACC 3QG5C 3QFNA 4H2BA 3DSCA 2HY1A 4JA9A 1S70A 2DXLA 4O24A 3ZTVA 4B2OA 4MOVA 4FBQA 2QFPA 2NYLC 2YEQA 3H66A 3E7AA 2IAEC 2ZBMA 3H63A 4J6OA 4IL1A 4MP0A 3DW8C 5B8IA 3N5UA 4I5LC 3THNA 3H61A 3H64A 2WDDA 3KBPA 4ORBA 3QFMA 3FGAC 4M0VA 4XPNA 3EGHA 3QFKA 3PSOA 2HYPA 4O43A 4Q7FA 1S95A 1NNWA 2DFJA 3T1IA 1S3LA 3C5WC 4KKZA 2USHA 4UWQA 1OIEA 1JK7A 2CV9A 4UT2A 4V0XA 3QFOA 3H62B 1OI8A 3RL5A 5JJTA 2WDFA 2KKNA 1V73A 1AUIA 4H1YP 5DNYA 3IB7A 2YVTA 2IE3C 4H2FA 3EGGA 4LU9A 3H67A 4O5GA 1QHWA 4NZVA 1FJMA 3AUZA 4ORAA 1WARA 4I5NC 3RL3A 2GJUA 3P71C 2NXFA 5F3WA 3H69A 1UTEA 5EQVA 4F0ZA 1WAO1 4YKEA 3V4YA 3D03A 3E0JA 2Z72A 2BDXA 3LL8A 3K7WC 3IVEA 2DXNA 4ZVZA 1G5BA 1XZWA 2P6BA 5JPFA 2HYOA 3GVEA 2NYMC 4DT2A 4JA7A 1XM7A 2XMOA 5JPEA 2WDCA 3JYFA 3E7BA 4FBWA 2JOGA 5IOHA 3IB8A 4OR9A
chains in the Genus database with same CATH topology
1SU1A 2NPPC 4FCXA 3ICFA 4H2IA 2ZOAA 2O8AA 1USHA 3ZU0A 3K7VC 4G9JA 5INBA 4FBKA 3HVQA 1MF8A 2BCDA 3AV0A 2BQ8X 1QFCA 1HPUA 1T70A 1Z2XA 1S8EA 4UT3B 3C9FA 5J28A 1W24A 1IT6A 3CK2A 4V0WA 5GTUA 4WWLA 4IYPC 1T71A 5C1VA 2IE4C 4TUGA 1OIDA 2A22A 1HO5A 2O8GA 3H60A 2QJCA 5HPEA 2WDEA 1U32A 3DSDA 4DHLA 2AHDA 4HD0A 1TCOA 1II7A 4H1SA 4TUIA 1M63A 4H2GA 3TGHA 4V0VA 3FLOA 3RL4A 3H68A 4DSYA 1HP1A 1KBPA 1S3MA 3RQZA 4ORCA 2QFRA 2R17A 1UF3A 4O4KA 4ZX2A 2Q8UA 2Z06A 4KBPA 4UT3A 3IVDA 4LTYA 1S3NA 3THOB 4MOYA 2Z1AA 1Z2WA 3PSNA 2ZO9B 4LACC 3QG5C 3QFNA 4H2BA 3DSCA 2HY1A 4JA9A 1S70A 2DXLA 4O24A 3ZTVA 4B2OA 4MOVA 4FBQA 2QFPA 2NYLC 2YEQA 3H66A 3E7AA 2IAEC 2ZBMA 3H63A 4J6OA 4IL1A 4MP0A 3DW8C 5B8IA 3N5UA 4I5LC 3THNA 3H61A 3H64A 2WDDA 3KBPA 4ORBA 3QFMA 3FGAC 4M0VA 4XPNA 3EGHA 3QFKA 3PSOA 2HYPA 4O43A 4Q7FA 1S95A 1NNWA 2DFJA 3T1IA 1S3LA 3C5WC 4KKZA 2USHA 4UWQA 1OIEA 1JK7A 2CV9A 4UT2A 4V0XA 3QFOA 3H62B 1OI8A 3RL5A 5JJTA 2WDFA 2KKNA 1V73A 1AUIA 4H1YP 5DNYA 3IB7A 2YVTA 2IE3C 4H2FA 3EGGA 4LU9A 3H67A 4O5GA 1QHWA 4NZVA 1FJMA 3AUZA 4ORAA 1WARA 4I5NC 3RL3A 2GJUA 3P71C 2NXFA 5F3WA 3H69A 1UTEA 5EQVA 4F0ZA 1WAO1 4YKEA 3V4YA 3D03A 3E0JA 2Z72A 2BDXA 3LL8A 3K7WC 3IVEA 2DXNA 4ZVZA 1G5BA 1XZWA 2P6BA 5JPFA 2HYOA 3GVEA 2NYMC 4DT2A 4JA7A 1XM7A 2XMOA 5JPEA 2WDCA 3JYFA 3E7BA 4FBWA 2JOGA 5IOHA 3IB8A 4OR9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SU1 A;  2NPP C;  4FCX A;  3ICF A;  4H2I A;  2O8A A;  1USH A;  3ZU0 A;  3K7V C;  4G9J A;  5INB A;  4FBK A;  3HVQ A;  1MF8 A;  2BCD A;  3AV0 A;  2BQ8 X;  1QFC A;  1HPU A;  1T70 A;  1Z2X A;  1S8E A;  4UT3 B;  3C9F A;  5J28 A;  1W24 A;  1IT6 A;  3CK2 A;  4V0W A;  5GTU A;  4WWL A;  4IYP C;  1T71 A;  5C1V A;  2IE4 C;  4TUG A;  1OID A;  2A22 A;  1HO5 A;  2O8G A;  3H60 A;  2QJC A;  5HPE A;  2WDE A;  1U32 A;  3DSD A;  4DHL A;  2AHD A;  4HD0 A;  1TCO A;  1II7 A;  4H1S A;  4TUI A;  1M63 A;  4H2G A;  3TGH A;  4V0V A;  3RL4 A;  3H68 A;  4DSY A;  1HP1 A;  1KBP A;  1S3M A;  3RQZ A;  4ORC A;  2QFR A;  2R17 A;  1UF3 A;  4O4K A;  4ZX2 A;  2Q8U A;  2Z06 A;  4KBP A;  4UT3 A;  3IVD A;  4LTY A;  1S3N A;  3THO B;  4MOY A;  2Z1A A;  1Z2W A;  3PSN A;  4LAC C;  3QG5 C;  3QFN A;  4H2B A;  3DSC A;  2HY1 A;  4JA9 A;  1S70 A;  4O24 A;  3ZTV A;  4B2O A;  4MOV A;  4FBQ A;  2QFP A;  2NYL C;  3H66 A;  3E7A A;  2IAE C;  2ZBM A;  3H63 A;  4J6O A;  4IL1 A;  4MP0 A;  3DW8 C;  5B8I A;  3N5U A;  4I5L C;  3THN A;  3H61 A;  3H64 A;  2WDD A;  3KBP A;  4ORB A;  3QFM A;  3FGA C;  4M0V A;  4XPN A;  3EGH A;  3QFK A;  3PSO A;  2HYP A;  4O43 A;  4Q7F A;  1S95 A;  1NNW A;  2DFJ A;  3T1I A;  1S3L A;  3C5W C;  4KKZ A;  2USH A;  4UWQ A;  1OIE A;  1JK7 A;  2CV9 A;  4UT2 A;  4V0X A;  3QFO A;  3H62 B;  1OI8 A;  3RL5 A;  5JJT A;  2WDF A;  2KKN A;  1V73 A;  1AUI A;  4H1Y P;  5DNY A;  3IB7 A;  2YVT A;  2IE3 C;  4H2F A;  3EGG A;  4LU9 A;  3H67 A;  4O5G A;  1QHW A;  4NZV A;  1FJM A;  3AUZ A;  4ORA A;  1WAR A;  4I5N C;  3RL3 A;  2GJU A;  3P71 C;  2NXF A;  5F3W A;  3H69 A;  1UTE A;  5EQV A;  4F0Z A;  1WAO 1;  4YKE A;  3V4Y A;  2Z72 A;  2BDX A;  3LL8 A;  3K7W C;  3IVE A;  4ZVZ A;  1G5B A;  1XZW A;  2P6B A;  5JPF A;  2HYO A;  3GVE A;  2NYM C;  4DT2 A;  4JA7 A;  1XM7 A;  2XMO A;  5JPE A;  2WDC A;  3JYF A;  3E7B A;  4FBW A;  2JOG A;  5IOH A;  3IB8 A;  4OR9 A; 
#chains in the Genus database with same CATH topology
 1SU1 A;  2NPP C;  4FCX A;  3ICF A;  4H2I A;  2ZOA A;  2O8A A;  1USH A;  3ZU0 A;  3K7V C;  4G9J A;  5INB A;  4FBK A;  3HVQ A;  1MF8 A;  2BCD A;  3AV0 A;  2BQ8 X;  1QFC A;  1HPU A;  1T70 A;  1Z2X A;  1S8E A;  4UT3 B;  3C9F A;  5J28 A;  1W24 A;  1IT6 A;  3CK2 A;  4V0W A;  5GTU A;  4WWL A;  4IYP C;  1T71 A;  5C1V A;  2IE4 C;  4TUG A;  1OID A;  2A22 A;  1HO5 A;  2O8G A;  3H60 A;  2QJC A;  5HPE A;  2WDE A;  1U32 A;  3DSD A;  4DHL A;  2AHD A;  4HD0 A;  1TCO A;  1II7 A;  4H1S A;  4TUI A;  1M63 A;  4H2G A;  3TGH A;  4V0V A;  3FLO A;  3RL4 A;  3H68 A;  4DSY A;  1HP1 A;  1KBP A;  1S3M A;  3RQZ A;  4ORC A;  2QFR A;  2R17 A;  1UF3 A;  4O4K A;  4ZX2 A;  2Q8U A;  2Z06 A;  4KBP A;  4UT3 A;  3IVD A;  4LTY A;  1S3N A;  3THO B;  4MOY A;  2Z1A A;  1Z2W A;  3PSN A;  2ZO9 B;  4LAC C;  3QG5 C;  3QFN A;  4H2B A;  3DSC A;  2HY1 A;  4JA9 A;  1S70 A;  2DXL A;  4O24 A;  3ZTV A;  4B2O A;  4MOV A;  4FBQ A;  2QFP A;  2NYL C;  2YEQ A;  3H66 A;  3E7A A;  2IAE C;  2ZBM A;  3H63 A;  4J6O A;  4IL1 A;  4MP0 A;  3DW8 C;  5B8I A;  3N5U A;  4I5L C;  3THN A;  3H61 A;  3H64 A;  2WDD A;  3KBP A;  4ORB A;  3QFM A;  3FGA C;  4M0V A;  4XPN A;  3EGH A;  3QFK A;  3PSO A;  2HYP A;  4O43 A;  4Q7F A;  1S95 A;  1NNW A;  2DFJ A;  3T1I A;  1S3L A;  3C5W C;  4KKZ A;  2USH A;  4UWQ A;  1OIE A;  1JK7 A;  2CV9 A;  4UT2 A;  4V0X A;  3QFO A;  3H62 B;  1OI8 A;  3RL5 A;  5JJT A;  2WDF A;  2KKN A;  1V73 A;  1AUI A;  4H1Y P;  5DNY A;  3IB7 A;  2YVT A;  2IE3 C;  4H2F A;  3EGG A;  4LU9 A;  3H67 A;  4O5G A;  1QHW A;  4NZV A;  1FJM A;  3AUZ A;  4ORA A;  1WAR A;  4I5N C;  3RL3 A;  2GJU A;  3P71 C;  2NXF A;  5F3W A;  3H69 A;  1UTE A;  5EQV A;  4F0Z A;  1WAO 1;  4YKE A;  3V4Y A;  3D03 A;  3E0J A;  2Z72 A;  2BDX A;  3LL8 A;  3K7W C;  3IVE A;  2DXN A;  4ZVZ A;  1G5B A;  1XZW A;  2P6B A;  5JPF A;  2HYO A;  3GVE A;  2NYM C;  4DT2 A;  4JA7 A;  1XM7 A;  2XMO A;  5JPE A;  2WDC A;  3JYF A;  3E7B A;  4FBW A;  2JOG A;  5IOH A;  3IB8 A;  4OR9 A; 
#chains in the Genus database with same CATH homology
 1SU1 A;  2NPP C;  4FCX A;  3ICF A;  4H2I A;  2ZOA A;  2O8A A;  1USH A;  3ZU0 A;  3K7V C;  4G9J A;  5INB A;  4FBK A;  3HVQ A;  1MF8 A;  2BCD A;  3AV0 A;  2BQ8 X;  1QFC A;  1HPU A;  1T70 A;  1Z2X A;  1S8E A;  4UT3 B;  3C9F A;  5J28 A;  1W24 A;  1IT6 A;  3CK2 A;  4V0W A;  5GTU A;  4WWL A;  4IYP C;  1T71 A;  5C1V A;  2IE4 C;  4TUG A;  1OID A;  2A22 A;  1HO5 A;  2O8G A;  3H60 A;  2QJC A;  5HPE A;  2WDE A;  1U32 A;  3DSD A;  4DHL A;  2AHD A;  4HD0 A;  1TCO A;  1II7 A;  4H1S A;  4TUI A;  1M63 A;  4H2G A;  3TGH A;  4V0V A;  3FLO A;  3RL4 A;  3H68 A;  4DSY A;  1HP1 A;  1KBP A;  1S3M A;  3RQZ A;  4ORC A;  2QFR A;  2R17 A;  1UF3 A;  4O4K A;  4ZX2 A;  2Q8U A;  2Z06 A;  4KBP A;  4UT3 A;  3IVD A;  4LTY A;  1S3N A;  3THO B;  4MOY A;  2Z1A A;  1Z2W A;  3PSN A;  2ZO9 B;  4LAC C;  3QG5 C;  3QFN A;  4H2B A;  3DSC A;  2HY1 A;  4JA9 A;  1S70 A;  2DXL A;  4O24 A;  3ZTV A;  4B2O A;  4MOV A;  4FBQ A;  2QFP A;  2NYL C;  2YEQ A;  3H66 A;  3E7A A;  2IAE C;  2ZBM A;  3H63 A;  4J6O A;  4IL1 A;  4MP0 A;  3DW8 C;  5B8I A;  3N5U A;  4I5L C;  3THN A;  3H61 A;  3H64 A;  2WDD A;  3KBP A;  4ORB A;  3QFM A;  3FGA C;  4M0V A;  4XPN A;  3EGH A;  3QFK A;  3PSO A;  2HYP A;  4O43 A;  4Q7F A;  1S95 A;  1NNW A;  2DFJ A;  3T1I A;  1S3L A;  3C5W C;  4KKZ A;  2USH A;  4UWQ A;  1OIE A;  1JK7 A;  2CV9 A;  4UT2 A;  4V0X A;  3QFO A;  3H62 B;  1OI8 A;  3RL5 A;  5JJT A;  2WDF A;  2KKN A;  1V73 A;  1AUI A;  4H1Y P;  5DNY A;  3IB7 A;  2YVT A;  2IE3 C;  4H2F A;  3EGG A;  4LU9 A;  3H67 A;  4O5G A;  1QHW A;  4NZV A;  1FJM A;  3AUZ A;  4ORA A;  1WAR A;  4I5N C;  3RL3 A;  2GJU A;  3P71 C;  2NXF A;  5F3W A;  3H69 A;  1UTE A;  5EQV A;  4F0Z A;  1WAO 1;  4YKE A;  3V4Y A;  3D03 A;  3E0J A;  2Z72 A;  2BDX A;  3LL8 A;  3K7W C;  3IVE A;  2DXN A;  4ZVZ A;  1G5B A;  1XZW A;  2P6B A;  5JPF A;  2HYO A;  3GVE A;  2NYM C;  4DT2 A;  4JA7 A;  1XM7 A;  2XMO A;  5JPE A;  2WDC A;  3JYF A;  3E7B A;  4FBW A;  2JOG A;  5IOH A;  3IB8 A;  4OR9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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