3LL8A

Crystal structure of calcineurin in complex with akap79 peptide
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
357
structure length
357
Chain Sequence
TDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/calcium binding protein
source organism Homo sapiens
publication title Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)-calcineurin-NFAT signaling.
pubmed doi rcsb
molecule keywords AKAP79 peptide
total genus 126
structure length 357
sequence length 357
chains with identical sequence C
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2010-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3ll8A00
4O43A 4TUGA 1S3NA 1XZWA 1XM7A 1U32A 3QFNA 2GJUA 3AV0A 3ZTVA 1OIEA 2WDCA 3CK2A 3ZU0A 2QFPA 4B2OA 4I5NC 3EGHA 4MP0A 5EQVA 4ORCA 2A22A 4JA7A 3DW8C 1Z2XA 1II7A 4ORAA 3TGHA 3FGAC 3IVDA 1OIDA 2USHA 3V4YA 4H2IA 4FCXA 2Z06A 3QFOA 3H63A 4DHLA 1S3MA 4DSYA 1HP1A 3K7WC 4O5GA 4H2BA 4H1YP 5HPEA 3IB7A 1AUIA 3RQZA 5C1VA 5JPEA 4YKEA 4Q7FA 1QFCA 1WAO1 2Q8UA 3QFKA 2NPPC 4IL1A 2IE3C 2WDFA 1G5BA 3JYFA 2R17A 3LL8A 5DNYA 1USHA 3H66A 1SU1A 1HPUA 2JOGA 3PSOA 4UT2A 1OI8A 1UF3A 4J6OA 4V0XA 3P71C 4H1SA 1HO5A 4KBPA 1S3LA 3DSCA 4I5LC 3IVEA 3K7VC 3RL3A 4V0VA 4ZX2A 2NXFA 5B8IA 1T71A 2IE4C 3N5UA 4UT3B 3RL4A 4ORBA 4TUIA 3AUZA 1JK7A 3KBPA 1QHWA 4HD0A 4G9JA 2WDEA 4O4KA 4FBQA 2Z72A 3DSDA 2QFRA 4MOVA 3H61A 4WWLA 4FBKA 1TCOA 4F0ZA 5J28A 2NYMC 2HYPA 2AHDA 2CV9A 2BCDA 2IAEC 2HYOA 1M63A 4LTYA 2ZBMA 2NYLC 1KBPA 2O8AA 5INBA 1UTEA 2BDXA 3H64A 3H68A 5GTUA 5F3WA 3THOB 1Z2WA 2BQ8X 1FJMA 4V0WA 4UWQA 4JA9A 3H60A 3RL5A 3H69A 3QFMA 1S8EA 2YVTA 1T70A 3C9FA 3H62B 2HY1A 4DT2A 2WDDA 2QJCA 1NNWA 1MF8A 3E7BA 5JPFA 3QG5C 4LACC 4ZVZA 3EGGA 4FBWA 1V73A 2P6BA 5IOHA 1IT6A 4OR9A 3C5WC 1W24A 3H67A 3ICFA 2DFJA 2KKNA 4MOYA 4O24A 2XMOA 5JJTA 4NZVA 2O8GA 1WARA 2Z1AA 3IB8A 1S95A 4H2GA 3THNA 3E7AA 4H2FA 4XPNA 4KKZA 3GVEA 3HVQA 4IYPC 1S70A 3T1IA 4UT3A 3PSNA 4M0VA 4LU9A
chains in the Genus database with same CATH superfamily
4O43A 4TUGA 1S3NA 1XZWA 1XM7A 1U32A 3QFNA 2GJUA 3AV0A 3ZTVA 1OIEA 2WDCA 3CK2A 3ZU0A 2QFPA 4B2OA 4I5NC 3EGHA 4MP0A 5EQVA 4ORCA 2A22A 4JA7A 3DW8C 1Z2XA 1II7A 4ORAA 3TGHA 3FGAC 3IVDA 1OIDA 2USHA 3V4YA 2ZO9B 4H2IA 4FCXA 2Z06A 3QFOA 3H63A 2YEQA 4DHLA 1S3MA 4DSYA 1HP1A 3K7WC 4O5GA 4H2BA 4H1YP 5HPEA 3IB7A 1AUIA 3RQZA 5C1VA 5JPEA 4YKEA 4Q7FA 1QFCA 1WAO1 2Q8UA 3QFKA 2NPPC 4IL1A 2IE3C 2WDFA 1G5BA 3JYFA 2R17A 3LL8A 5DNYA 1USHA 3H66A 1SU1A 1HPUA 2JOGA 3PSOA 4UT2A 1OI8A 1UF3A 4J6OA 4V0XA 3P71C 4H1SA 1HO5A 4KBPA 1S3LA 3DSCA 4I5LC 3IVEA 3K7VC 3RL3A 4V0VA 4ZX2A 2NXFA 5B8IA 1T71A 2IE4C 3N5UA 4UT3B 3RL4A 4ORBA 4TUIA 3AUZA 1JK7A 3KBPA 1QHWA 4HD0A 4G9JA 2WDEA 4O4KA 4FBQA 2Z72A 3DSDA 2QFRA 4MOVA 3H61A 4WWLA 4FBKA 1TCOA 4F0ZA 5J28A 2NYMC 2HYPA 2AHDA 2CV9A 2BCDA 2IAEC 2HYOA 1M63A 4LTYA 2ZBMA 2NYLC 1KBPA 2O8AA 5INBA 1UTEA 2BDXA 3E0JA 3H64A 3H68A 5GTUA 3THOB 1Z2WA 2BQ8X 1FJMA 4V0WA 4UWQA 2DXLA 4JA9A 3H60A 3RL5A 3H69A 3QFMA 3FLOA 1S8EA 2YVTA 1T70A 3D03A 3C9FA 3H62B 2HY1A 4DT2A 2WDDA 2QJCA 1NNWA 1MF8A 3E7BA 5JPFA 3QG5C 4LACC 4ZVZA 3EGGA 4FBWA 1V73A 2P6BA 5IOHA 5F3WA 1IT6A 4OR9A 3C5WC 1W24A 3H67A 3ICFA 2DFJA 2KKNA 4MOYA 4O24A 2XMOA 5JJTA 4NZVA 2O8GA 4LU9A 1WARA 2Z1AA 3IB8A 1S95A 4H2GA 3THNA 3E7AA 4H2FA 4XPNA 4KKZA 3GVEA 3HVQA 4IYPC 1S70A 3T1IA 4UT3A 3PSNA 4M0VA 2DXNA 2ZOAA
chains in the Genus database with same CATH topology
4O43A 4TUGA 1S3NA 1XZWA 1XM7A 1U32A 3QFNA 2GJUA 3AV0A 3ZTVA 1OIEA 2WDCA 3CK2A 3ZU0A 2QFPA 4B2OA 4I5NC 3EGHA 4MP0A 5EQVA 4ORCA 2A22A 4JA7A 3DW8C 1Z2XA 1II7A 4ORAA 3TGHA 3FGAC 3IVDA 1OIDA 2USHA 3V4YA 2ZO9B 4H2IA 4FCXA 2Z06A 3QFOA 3H63A 2YEQA 4DHLA 1S3MA 4DSYA 1HP1A 3K7WC 4O5GA 4H2BA 4H1YP 5HPEA 3IB7A 1AUIA 3RQZA 5C1VA 5JPEA 4YKEA 4Q7FA 1QFCA 1WAO1 2Q8UA 3QFKA 2NPPC 4IL1A 2IE3C 2WDFA 1G5BA 3JYFA 2R17A 3LL8A 5DNYA 1USHA 3H66A 1SU1A 1HPUA 2JOGA 3PSOA 4UT2A 1OI8A 1UF3A 4J6OA 4V0XA 3P71C 4H1SA 1HO5A 4KBPA 1S3LA 3DSCA 4I5LC 3IVEA 3K7VC 3RL3A 4V0VA 4ZX2A 2NXFA 5B8IA 1T71A 2IE4C 3N5UA 4UT3B 3RL4A 4ORBA 4TUIA 3AUZA 1JK7A 3KBPA 1QHWA 4HD0A 4G9JA 2WDEA 4O4KA 4FBQA 2Z72A 3DSDA 2QFRA 4MOVA 3H61A 4WWLA 4FBKA 1TCOA 4F0ZA 5J28A 2NYMC 2HYPA 2AHDA 2CV9A 2BCDA 2IAEC 2HYOA 1M63A 4LTYA 2ZBMA 2NYLC 1KBPA 2O8AA 5INBA 1UTEA 2BDXA 3E0JA 3H64A 3H68A 5GTUA 3THOB 1Z2WA 2BQ8X 1FJMA 4V0WA 4UWQA 2DXLA 4JA9A 3H60A 3RL5A 3H69A 3QFMA 3FLOA 1S8EA 2YVTA 1T70A 3D03A 3C9FA 3H62B 2HY1A 4DT2A 2WDDA 2QJCA 1NNWA 1MF8A 3E7BA 5JPFA 3QG5C 4LACC 4ZVZA 3EGGA 4FBWA 1V73A 2P6BA 5IOHA 5F3WA 1IT6A 4OR9A 3C5WC 1W24A 3H67A 3ICFA 2DFJA 2KKNA 4MOYA 4O24A 2XMOA 5JJTA 4NZVA 2O8GA 4LU9A 1WARA 2Z1AA 3IB8A 1S95A 4H2GA 3THNA 3E7AA 4H2FA 4XPNA 4KKZA 3GVEA 3HVQA 4IYPC 1S70A 3T1IA 4UT3A 3PSNA 4M0VA 2DXNA 2ZOAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O43 A;  4TUG A;  1S3N A;  1XZW A;  1XM7 A;  1U32 A;  3QFN A;  2GJU A;  3AV0 A;  3ZTV A;  1OIE A;  2WDC A;  3CK2 A;  3ZU0 A;  2QFP A;  4B2O A;  4I5N C;  3EGH A;  4MP0 A;  5EQV A;  4ORC A;  2A22 A;  4JA7 A;  3DW8 C;  1Z2X A;  1II7 A;  4ORA A;  3TGH A;  3FGA C;  3IVD A;  1OID A;  2USH A;  3V4Y A;  4H2I A;  4FCX A;  2Z06 A;  3QFO A;  3H63 A;  4DHL A;  1S3M A;  4DSY A;  1HP1 A;  3K7W C;  4O5G A;  4H2B A;  4H1Y P;  5HPE A;  3IB7 A;  1AUI A;  3RQZ A;  5C1V A;  5JPE A;  4YKE A;  4Q7F A;  1QFC A;  1WAO 1;  2Q8U A;  3QFK A;  2NPP C;  4IL1 A;  2IE3 C;  2WDF A;  1G5B A;  3JYF A;  2R17 A;  3LL8 A;  5DNY A;  1USH A;  3H66 A;  1SU1 A;  1HPU A;  2JOG A;  3PSO A;  4UT2 A;  1OI8 A;  1UF3 A;  4J6O A;  4V0X A;  3P71 C;  4H1S A;  1HO5 A;  4KBP A;  1S3L A;  3DSC A;  4I5L C;  3IVE A;  3K7V C;  3RL3 A;  4V0V A;  4ZX2 A;  2NXF A;  5B8I A;  1T71 A;  2IE4 C;  3N5U A;  4UT3 B;  3RL4 A;  4ORB A;  4TUI A;  3AUZ A;  1JK7 A;  3KBP A;  1QHW A;  4HD0 A;  4G9J A;  2WDE A;  4O4K A;  4FBQ A;  2Z72 A;  3DSD A;  2QFR A;  4MOV A;  3H61 A;  4WWL A;  4FBK A;  1TCO A;  4F0Z A;  5J28 A;  2NYM C;  2HYP A;  2AHD A;  2CV9 A;  2BCD A;  2IAE C;  2HYO A;  1M63 A;  4LTY A;  2ZBM A;  2NYL C;  1KBP A;  2O8A A;  5INB A;  1UTE A;  2BDX A;  3H64 A;  3H68 A;  5GTU A;  5F3W A;  3THO B;  1Z2W A;  2BQ8 X;  1FJM A;  4V0W A;  4UWQ A;  4JA9 A;  3H60 A;  3RL5 A;  3H69 A;  3QFM A;  1S8E A;  2YVT A;  1T70 A;  3C9F A;  3H62 B;  2HY1 A;  4DT2 A;  2WDD A;  2QJC A;  1NNW A;  1MF8 A;  3E7B A;  5JPF A;  3QG5 C;  4LAC C;  4ZVZ A;  3EGG A;  4FBW A;  1V73 A;  2P6B A;  5IOH A;  1IT6 A;  4OR9 A;  3C5W C;  1W24 A;  3H67 A;  3ICF A;  2DFJ A;  2KKN A;  4MOY A;  4O24 A;  2XMO A;  5JJT A;  4NZV A;  2O8G A;  1WAR A;  2Z1A A;  3IB8 A;  1S95 A;  4H2G A;  3THN A;  3E7A A;  4H2F A;  4XPN A;  4KKZ A;  3GVE A;  3HVQ A;  4IYP C;  1S70 A;  3T1I A;  4UT3 A;  3PSN A;  4M0V A;  4LU9 A; 
#chains in the Genus database with same CATH topology
 4O43 A;  4TUG A;  1S3N A;  1XZW A;  1XM7 A;  1U32 A;  3QFN A;  2GJU A;  3AV0 A;  3ZTV A;  1OIE A;  2WDC A;  3CK2 A;  3ZU0 A;  2QFP A;  4B2O A;  4I5N C;  3EGH A;  4MP0 A;  5EQV A;  4ORC A;  2A22 A;  4JA7 A;  3DW8 C;  1Z2X A;  1II7 A;  4ORA A;  3TGH A;  3FGA C;  3IVD A;  1OID A;  2USH A;  3V4Y A;  2ZO9 B;  4H2I A;  4FCX A;  2Z06 A;  3QFO A;  3H63 A;  2YEQ A;  4DHL A;  1S3M A;  4DSY A;  1HP1 A;  3K7W C;  4O5G A;  4H2B A;  4H1Y P;  5HPE A;  3IB7 A;  1AUI A;  3RQZ A;  5C1V A;  5JPE A;  4YKE A;  4Q7F A;  1QFC A;  1WAO 1;  2Q8U A;  3QFK A;  2NPP C;  4IL1 A;  2IE3 C;  2WDF A;  1G5B A;  3JYF A;  2R17 A;  3LL8 A;  5DNY A;  1USH A;  3H66 A;  1SU1 A;  1HPU A;  2JOG A;  3PSO A;  4UT2 A;  1OI8 A;  1UF3 A;  4J6O A;  4V0X A;  3P71 C;  4H1S A;  1HO5 A;  4KBP A;  1S3L A;  3DSC A;  4I5L C;  3IVE A;  3K7V C;  3RL3 A;  4V0V A;  4ZX2 A;  2NXF A;  5B8I A;  1T71 A;  2IE4 C;  3N5U A;  4UT3 B;  3RL4 A;  4ORB A;  4TUI A;  3AUZ A;  1JK7 A;  3KBP A;  1QHW A;  4HD0 A;  4G9J A;  2WDE A;  4O4K A;  4FBQ A;  2Z72 A;  3DSD A;  2QFR A;  4MOV A;  3H61 A;  4WWL A;  4FBK A;  1TCO A;  4F0Z A;  5J28 A;  2NYM C;  2HYP A;  2AHD A;  2CV9 A;  2BCD A;  2IAE C;  2HYO A;  1M63 A;  4LTY A;  2ZBM A;  2NYL C;  1KBP A;  2O8A A;  5INB A;  1UTE A;  2BDX A;  3E0J A;  3H64 A;  3H68 A;  5GTU A;  3THO B;  1Z2W A;  2BQ8 X;  1FJM A;  4V0W A;  4UWQ A;  2DXL A;  4JA9 A;  3H60 A;  3RL5 A;  3H69 A;  3QFM A;  3FLO A;  1S8E A;  2YVT A;  1T70 A;  3D03 A;  3C9F A;  3H62 B;  2HY1 A;  4DT2 A;  2WDD A;  2QJC A;  1NNW A;  1MF8 A;  3E7B A;  5JPF A;  3QG5 C;  4LAC C;  4ZVZ A;  3EGG A;  4FBW A;  1V73 A;  2P6B A;  5IOH A;  5F3W A;  1IT6 A;  4OR9 A;  3C5W C;  1W24 A;  3H67 A;  3ICF A;  2DFJ A;  2KKN A;  4MOY A;  4O24 A;  2XMO A;  5JJT A;  4NZV A;  2O8G A;  4LU9 A;  1WAR A;  2Z1A A;  3IB8 A;  1S95 A;  4H2G A;  3THN A;  3E7A A;  4H2F A;  4XPN A;  4KKZ A;  3GVE A;  3HVQ A;  4IYP C;  1S70 A;  3T1I A;  4UT3 A;  3PSN A;  4M0V A;  2DXN A;  2ZOA A; 
#chains in the Genus database with same CATH homology
 4O43 A;  4TUG A;  1S3N A;  1XZW A;  1XM7 A;  1U32 A;  3QFN A;  2GJU A;  3AV0 A;  3ZTV A;  1OIE A;  2WDC A;  3CK2 A;  3ZU0 A;  2QFP A;  4B2O A;  4I5N C;  3EGH A;  4MP0 A;  5EQV A;  4ORC A;  2A22 A;  4JA7 A;  3DW8 C;  1Z2X A;  1II7 A;  4ORA A;  3TGH A;  3FGA C;  3IVD A;  1OID A;  2USH A;  3V4Y A;  2ZO9 B;  4H2I A;  4FCX A;  2Z06 A;  3QFO A;  3H63 A;  2YEQ A;  4DHL A;  1S3M A;  4DSY A;  1HP1 A;  3K7W C;  4O5G A;  4H2B A;  4H1Y P;  5HPE A;  3IB7 A;  1AUI A;  3RQZ A;  5C1V A;  5JPE A;  4YKE A;  4Q7F A;  1QFC A;  1WAO 1;  2Q8U A;  3QFK A;  2NPP C;  4IL1 A;  2IE3 C;  2WDF A;  1G5B A;  3JYF A;  2R17 A;  3LL8 A;  5DNY A;  1USH A;  3H66 A;  1SU1 A;  1HPU A;  2JOG A;  3PSO A;  4UT2 A;  1OI8 A;  1UF3 A;  4J6O A;  4V0X A;  3P71 C;  4H1S A;  1HO5 A;  4KBP A;  1S3L A;  3DSC A;  4I5L C;  3IVE A;  3K7V C;  3RL3 A;  4V0V A;  4ZX2 A;  2NXF A;  5B8I A;  1T71 A;  2IE4 C;  3N5U A;  4UT3 B;  3RL4 A;  4ORB A;  4TUI A;  3AUZ A;  1JK7 A;  3KBP A;  1QHW A;  4HD0 A;  4G9J A;  2WDE A;  4O4K A;  4FBQ A;  2Z72 A;  3DSD A;  2QFR A;  4MOV A;  3H61 A;  4WWL A;  4FBK A;  1TCO A;  4F0Z A;  5J28 A;  2NYM C;  2HYP A;  2AHD A;  2CV9 A;  2BCD A;  2IAE C;  2HYO A;  1M63 A;  4LTY A;  2ZBM A;  2NYL C;  1KBP A;  2O8A A;  5INB A;  1UTE A;  2BDX A;  3E0J A;  3H64 A;  3H68 A;  5GTU A;  3THO B;  1Z2W A;  2BQ8 X;  1FJM A;  4V0W A;  4UWQ A;  2DXL A;  4JA9 A;  3H60 A;  3RL5 A;  3H69 A;  3QFM A;  3FLO A;  1S8E A;  2YVT A;  1T70 A;  3D03 A;  3C9F A;  3H62 B;  2HY1 A;  4DT2 A;  2WDD A;  2QJC A;  1NNW A;  1MF8 A;  3E7B A;  5JPF A;  3QG5 C;  4LAC C;  4ZVZ A;  3EGG A;  4FBW A;  1V73 A;  2P6B A;  5IOH A;  5F3W A;  1IT6 A;  4OR9 A;  3C5W C;  1W24 A;  3H67 A;  3ICF A;  2DFJ A;  2KKN A;  4MOY A;  4O24 A;  2XMO A;  5JJT A;  4NZV A;  2O8G A;  4LU9 A;  1WAR A;  2Z1A A;  3IB8 A;  1S95 A;  4H2G A;  3THN A;  3E7A A;  4H2F A;  4XPN A;  4KKZ A;  3GVE A;  3HVQ A;  4IYP C;  1S70 A;  3T1I A;  4UT3 A;  3PSN A;  4M0V A;  2DXN A;  2ZOA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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