3LWQB

Structure of h/aca rnp bound to a substrate rna containing 3mu
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
51
structure length
51
Chain Sequence
RIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase .
pubmed doi rcsb
molecule tags Isomerase/rna binding protein/rna
source organism Pyrococcus furiosus
molecule keywords Pseudouridine synthase Cbf5
total genus 5
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 2010-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04135 Nop10p Nucleolar RNA-binding protein, Nop10p family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.40 Mainly Beta Single Sheet Rubrerythrin, domain 2 H/ACA ribonucleoprotein complex, subunit Nop10 3lwqB00
3LWQB 3MQKB 2AUSB 3HJWB 2EY4E 2APOB 2RFKB 3LWOB 3LWRB 2HVYC 3HJYB 3HAXC 3LWPB 3LWVB 2AQCA
chains in the Genus database with same CATH superfamily
5EINC 2VUML 2JI3A 3H0GL 5C4JL 3M3YL 1R0HA 1QYBA 1VCXA 2CKCA 2NYDA 5IYDL 2V3BB 1YK5A 2APOB 4A3DL 3LPEB 2C6AA 4AI3A 4BBRL 1RDVA 1YUXA 4XXBB 3CQZL 2R7ZL 3P8BA 3B0AB 3LWOB 2M6OA 2A69D 4A3LL 3H9CA 1PFUA 2WAQP 1TWGL 2A6HD 2HVYC 4A3IL 1P7PA 1T9PA 5AN9H 5C44L 5M3ML 3PIO1 1I6HL 3MQKB 1FHHA 2AYJA 3PL5A 2CKAA 3HAXC 3K7AL 4BBSL 5IYCL 4AI1A 2JI2A 3PKJA 4A3EL 2L0ZA 3HOXL 5MGNA 4A3CL 1DX8A 2O5JD 4AI0A 3GTQL 1RYTA 1BFYA 4TPUA 5DM71 1IU6A 5IYBL 4A3KL 1VZHA 5AI3A 1IRNA 3S1NL 2KN9A 2PVXA 4AYBP 4YWLA 2E2IL 2WB1P 2MS3A 2XJVA 3KYYA 1NXGA 4AR3A 1YUZA 1NNQA 4A3FL 1VZIA 3K35A 2JA8L 2Y0SP 4BY7L 1R0FA 2PMZP 1TWCL 4RXNA 1C09A 1B2JA 5MF6A 1Y1WL 3MPSA 4JAEA 1T9OA 2J9UB 3QVDA 3PO2L 3HOVL 3S1ML 1OWBA 4LHLA 2E2JL 5M5XL 3J7Z1 3HOZL 4ZN1B 3GTKL 4C3IL 4C3JL 4UY81 4G6BA 5IY0A 3PZAA 1ZRPA 4A3JL 1VZGA 3S17L 3HJWB 4A3BL 1DVBA 2B5ID 1K83L 1SMUA 5MLC3 5MFZA 4AR4A 2A68D 4LHNA 2CR8A 5M5YL 1Z92B 4POFA 4B8CD 4ZN3B 4A93L 2PPTA 2XJTA 2XJUA 5DM61 1B2OA 4WFN1 5JVH1 2AUSB 1TWHL 3NFPI 3KYVA 3S1RL 4POGA 5M5WL 3PO3L 2DSXA 5C3EL 3S2HL 3B08B 3PIP1 3I4NL 3JR7A 3H9BA 1BQ8A 1NXEA 2RFKB 2M4YA 2JA5L 4Y52L 3FKIL 1SMMA 3ZG6A 5C4XL 1QQTA 2BE5D 3PKIA 1TWFL 1PFYA 2YU9L 1BRFA 1H7VA 1R0IA 3P2AA 1IU5A 2V0FA 4AI2A 4JADA 5MFPA 1RYQA 2NVTL 5GADc 1WJVA 1B71A 2NVYL 1R9TL 2AQCA 3KYUA 1PFWA 5H1Sc 2C6BA 3H97A 3RYGA 5FLML 2PVEA 4AHYA 2LCQA 1TWAL 1E8JA 1BE7A 2XJQA 3WWLA 3LWQB 3HKZP 4K9FA 1S30A 4ME3A 3RZOL 3KYXA 1B13A 3H99A 5FJ8L 3SS2A 2Z3RB 3HOYL 1S2ZA 4Y7NL 4YWMA 2JI1A 3LNLA 4BY1L 3HOUL 1JYBA 2ZIXA 2ERSA 4U671 3LWPB 4BXXL 3VPBE 1QCVA 1I50L 3LWRB 5M3FL 3PWFA 5GAGc 3J7Y1 4E6YA 4QIWP 2RDVA 2QL0A 4AHXA 4AHWA 5JVG1 3GTLL 2HR5A 3RZ6A 2XJSA 3GTOL 4X6AL 3WWNB 1LKOA 1FHMA 1YV1A 3GTGL 3GTML 1PFVA 5GAHc 3I4ML 2PSMC 2EY4E 2K2DA 1I3QL 4GS7D 3HOWL 3GTPL 4C2M1 3M4OL 3S2DL 5GAEc 2NVQL 2B63L 1WCML 2M6PA 5RXNA 5IP9L 5K2ME 2JA6L 1Y1VL 1SMWA 2GMGA 3MSUA 2NVXL 1RWDA 3S15L 5IP7L 2ERJA 1IW7D 2XJRA 3HJYB 3S1QL 1OWCA 1RDGA 2KKDA 3FDJA 1S24A 1YK4A 1R0JA 1CADA 2M4VA 1PZXA 2H12A 4JAFA 5EIOC 3KYWA 1SFOL 3GTJL 1IROA 5AI2A 3A44A 3RZTA 1CAAA 2XJPA 2VL6A 6RXNA 1BQ9A 4A3ML 1LKMA 2V0EA 4AHZA 3QQCE 3S16L 4C3HL 4A3GL 1LKPA 3IU3I 3H3VM 1ODHA 2JA7L 1R0GA 3S14L 3RZDL 2A6ED 4TVMA 8RXNA 3LWVB 4AR5A 4V196 4AR6A 1F4LA 2Z3QB 2E2HL 1RB9A 7RXNA 4XGHA 2PYAA 1LTLA 2R93L 1T9QA 2R92L 4JAGA
chains in the Genus database with same CATH topology
3LWQB 3MQKB 2AUSB 3HJWB 2EY4E 2APOB 2RFKB 3LWOB 3LWRB 2HVYC 3HJYB 3HAXC 3LWPB 3LWVB 2AQCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LWQ B;  3MQK B;  2AUS B;  3HJW B;  2EY4 E;  2APO B;  2RFK B;  3LWO B;  3LWR B;  2HVY C;  3HJY B;  3HAX C;  3LWP B;  3LWV B;  2AQC A; 
#chains in the Genus database with same CATH topology
 5EIN C;  2VUM L;  2JI3 A;  3H0G L;  5C4J L;  3M3Y L;  1R0H A;  1QYB A;  1VCX A;  2CKC A;  2NYD A;  5IYD L;  2V3B B;  1YK5 A;  2APO B;  4A3D L;  3LPE B;  2C6A A;  4AI3 A;  4BBR L;  1RDV A;  1YUX A;  4XXB B;  3CQZ L;  2R7Z L;  3P8B A;  3B0A B;  3LWO B;  2M6O A;  2A69 D;  4A3L L;  3H9C A;  1PFU A;  2WAQ P;  1TWG L;  2A6H D;  2HVY C;  4A3I L;  1P7P A;  1T9P A;  5AN9 H;  5C44 L;  5M3M L;  3PIO 1;  1I6H L;  3MQK B;  1FHH A;  2AYJ A;  3PL5 A;  2CKA A;  3HAX C;  3K7A L;  4BBS L;  5IYC L;  4AI1 A;  2JI2 A;  3PKJ A;  4A3E L;  2L0Z A;  3HOX L;  5MGN A;  4A3C L;  1DX8 A;  2O5J D;  4AI0 A;  3GTQ L;  1RYT A;  1BFY A;  4TPU A;  5DM7 1;  1IU6 A;  5IYB L;  4A3K L;  1VZH A;  5AI3 A;  1IRN A;  3S1N L;  2KN9 A;  2PVX A;  4AYB P;  4YWL A;  2E2I L;  2WB1 P;  2MS3 A;  2XJV A;  3KYY A;  1NXG A;  4AR3 A;  1YUZ A;  1NNQ A;  4A3F L;  1VZI A;  3K35 A;  2JA8 L;  2Y0S P;  4BY7 L;  1R0F A;  2PMZ P;  1TWC L;  4RXN A;  1C09 A;  1B2J A;  5MF6 A;  1Y1W L;  3MPS A;  4JAE A;  1T9O A;  2J9U B;  3QVD A;  3PO2 L;  3HOV L;  3S1M L;  1OWB A;  4LHL A;  2E2J L;  5M5X L;  3J7Z 1;  3HOZ L;  4ZN1 B;  3GTK L;  4C3I L;  4C3J L;  4UY8 1;  4G6B A;  5IY0 A;  3PZA A;  1ZRP A;  4A3J L;  1VZG A;  3S17 L;  3HJW B;  4A3B L;  1DVB A;  2B5I D;  1K83 L;  1SMU A;  5MLC 3;  5MFZ A;  4AR4 A;  2A68 D;  4LHN A;  2CR8 A;  5M5Y L;  1Z92 B;  4POF A;  4B8C D;  4ZN3 B;  4A93 L;  2PPT A;  2XJT A;  2XJU A;  5DM6 1;  1B2O A;  4WFN 1;  5JVH 1;  2AUS B;  1TWH L;  3NFP I;  3KYV A;  3S1R L;  4POG A;  5M5W L;  3PO3 L;  2DSX A;  5C3E L;  3S2H L;  3B08 B;  3PIP 1;  3I4N L;  3JR7 A;  3H9B A;  1BQ8 A;  1NXE A;  2RFK B;  2M4Y A;  2JA5 L;  4Y52 L;  3FKI L;  1SMM A;  3ZG6 A;  5C4X L;  1QQT A;  2BE5 D;  3PKI A;  1TWF L;  1PFY A;  2YU9 L;  1BRF A;  1H7V A;  1R0I A;  3P2A A;  1IU5 A;  2V0F A;  4AI2 A;  4JAD A;  5MFP A;  1RYQ A;  2NVT L;  5GAD c;  1WJV A;  1B71 A;  2NVY L;  1R9T L;  2AQC A;  3KYU A;  1PFW A;  5H1S c;  2C6B A;  3H97 A;  3RYG A;  5FLM L;  2PVE A;  4AHY A;  2LCQ A;  1TWA L;  1E8J A;  1BE7 A;  2XJQ A;  3WWL A;  3LWQ B;  3HKZ P;  4K9F A;  1S30 A;  4ME3 A;  3RZO L;  3KYX A;  1B13 A;  3H99 A;  5FJ8 L;  3SS2 A;  2Z3R B;  3HOY L;  1S2Z A;  4Y7N L;  4YWM A;  2JI1 A;  3LNL A;  4BY1 L;  3HOU L;  1JYB A;  2ZIX A;  2ERS A;  4U67 1;  3LWP B;  4BXX L;  3VPB E;  1QCV A;  1I50 L;  3LWR B;  5M3F L;  3PWF A;  5GAG c;  3J7Y 1;  4E6Y A;  4QIW P;  2RDV A;  2QL0 A;  4AHX A;  4AHW A;  5JVG 1;  3GTL L;  2HR5 A;  3RZ6 A;  2XJS A;  3GTO L;  4X6A L;  3WWN B;  1LKO A;  1FHM A;  1YV1 A;  3GTG L;  3GTM L;  1PFV A;  5GAH c;  3I4M L;  2PSM C;  2EY4 E;  2K2D A;  1I3Q L;  4GS7 D;  3HOW L;  3GTP L;  4C2M 1;  3M4O L;  3S2D L;  5GAE c;  2NVQ L;  2B63 L;  1WCM L;  2M6P A;  5RXN A;  5IP9 L;  5K2M E;  2JA6 L;  1Y1V L;  1SMW A;  2GMG A;  3MSU A;  2NVX L;  1RWD A;  3S15 L;  5IP7 L;  2ERJ A;  1IW7 D;  2XJR A;  3HJY B;  3S1Q L;  1OWC A;  1RDG A;  2KKD A;  3FDJ A;  1S24 A;  1YK4 A;  1R0J A;  1CAD A;  2M4V A;  1PZX A;  2H12 A;  4JAF A;  5EIO C;  3KYW A;  1SFO L;  3GTJ L;  1IRO A;  5AI2 A;  3A44 A;  3RZT A;  1CAA A;  2XJP A;  2VL6 A;  6RXN A;  1BQ9 A;  4A3M L;  1LKM A;  2V0E A;  4AHZ A;  3QQC E;  3S16 L;  4C3H L;  4A3G L;  1LKP A;  3IU3 I;  3H3V M;  1ODH A;  2JA7 L;  1R0G A;  3S14 L;  3RZD L;  2A6E D;  4TVM A;  8RXN A;  3LWV B;  4AR5 A;  4V19 6;  4AR6 A;  1F4L A;  2Z3Q B;  2E2H L;  1RB9 A;  7RXN A;  4XGH A;  2PYA A;  1LTL A;  2R93 L;  1T9Q A;  2R92 L;  4JAG A; 
#chains in the Genus database with same CATH homology
 3LWQ B;  3MQK B;  2AUS B;  3HJW B;  2EY4 E;  2APO B;  2RFK B;  3LWO B;  3LWR B;  2HVY C;  3HJY B;  3HAX C;  3LWP B;  3LWV B;  2AQC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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