3LWQB

Structure of h/aca rnp bound to a substrate rna containing 3mu
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
51
structure length
51
Chain Sequence
RIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase .
pubmed doi rcsb
molecule tags Isomerase/rna binding protein/rna
source organism Pyrococcus furiosus
molecule keywords Pseudouridine synthase Cbf5
total genus 5
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 2010-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04135 Nop10p Nucleolar RNA-binding protein, Nop10p family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.40 Mainly Beta Single Sheet Rubrerythrin, domain 2 H/ACA ribonucleoprotein complex, subunit Nop10 3lwqB00
2HVYC 3LWPB 3LWRB 3HAXC 3HJWB 2EY4E 2AUSB 2APOB 3MQKB 3HJYB 2AQCA 3LWVB 3LWOB 3LWQB 2RFKB
chains in the Genus database with same CATH superfamily
5GAGc 3IU3I 1YUZA 1C09A 1TWCL 7RXNA 4B8CD 5GADc 2NVXL 2J9UB 5C44L 3HAXC 1WJVA 2ERJA 8RXNA 2XJUA 1PFYA 4AYBP 3PL5A 4AI2A 1NXEA 4A3DL 4A3KL 2PSMC 3H0GL 2PVXA 3LPEB 2XJRA 5C4JL 5JVG1 5JVH1 1YK5A 2XJTA 1YV1A 3LNLA 3S17L 1IU5A 5AI2A 5RXNA 4AI0A 3S1NL 2O5JD 3HKZP 1RB9A 2NVTL 1E8JA 2XJVA 3PIO1 2KKDA 2RFKB 2YU9L 2HVYC 1T9QA 3WWLA 3VPBE 2QL0A 4C3IL 2M6PA 1BFYA 4AR4A 4XGHA 3FDJA 5IP7L 4E6YA 1IRNA 4ME3A 5C4XL 4C2M1 1DX8A 5MLC3 4X6AL 4TVMA 4A3IL 6RXNA 5DM61 1PFUA 1VZIA 1R0GA 3FKIL 1BRFA 2WB1P 4V196 5AI3A 5M5XL 3GTLL 1I3QL 3LWRB 4AHXA 4K9FA 3NFPI 3QQCE 4ZN1B 1QYBA 5M5WL 4A3LL 4BY7L 1T9OA 1H7VA 1VZGA 2E2JL 3B08B 2KN9A 1NNQA 2R93L 4QIWP 5MF6A 3KYXA 4AHYA 4WFN1 3HJYB 3WWNB 1FHMA 3S14L 2PVEA 4BY1L 3MQKB 2MS3A 4A93L 2Z3QB 4AI1A 3GTJL 1S30A 4BBRL 4G6BA 4A3EL 5H1Sc 1CADA 1YUXA 3QVDA 5K2ME 3KYUA 2NVYL 2JI1A 3LWVB 1QCVA 4ZN3B 1IROA 3S1RL 2A6ED 1TWGL 5IYBL 3HJWB 3P8BA 4A3BL 3PZAA 4TPUA 1I50L 1NXGA 2DSXA 5FJ8L 3S15L 2JI3A 2ERSA 1IU6A 4AR5A 5DM71 2CR8A 2R7ZL 4BBSL 2JA7L 3PO3L 2BE5D 1RYQA 2Z3RB 4YWMA 3HOVL 3H99A 1SMUA 3S16L 1IW7D 4A3ML 2JA5L 3J7Y1 2RDVA 1JYBA 2V0EA 2NYDA 1QQTA 2E2IL 2M4YA 1CAAA 5MFZA 2PMZP 2XJPA 1TWAL 1YK4A 1T9PA 5M3ML 3GTOL 4UY81 2XJQA 2AQCA 1R0IA 4BXXL 4GS7D 1S24A 1RDGA 1B2OA 1K83L 2WAQP 1BE7A 1ZRPA 5EIOC 3J7Z1 3M4OL 5M3FL 3I4NL 1DVBA 2A69D 1B13A 1BQ8A 2XJSA 2CKCA 4XXBB 3MSUA 2VUML 5IYDL 2JA6L 1RDVA 3GTML 3RYGA 1RWDA 3RZTA 3CQZL 3ZG6A 3LWPB 2AYJA 5M5YL 4U671 5IYCL 3K35A 3HOUL 4Y7NL 5FLML 3H9CA 5AN9H 3PKJA 4JADA 1SMWA 4YWLA 1ODHA 2CKAA 3MPSA 4POGA 3H97A 1FHHA 2V0FA 1TWHL 2L0ZA 1R0FA 1S2ZA 5GAHc 1VZHA 3KYYA 3PKIA 3S2HL 5IY0A 2H12A 4AR3A 2B63L 3PWFA 4JAEA 1I6HL 1P7PA 3GTGL 1R0JA 1LKOA 2R92L 5GAEc 1LKPA 2B5ID 2NVQL 2AUSB 4LHLA 2ZIXA 1PZXA 2V3BB 4C3JL 1BQ9A 1Z92B 1PFWA 1TWFL 3RZ6A 1OWCA 1SMMA 4A3CL 2A6HD 4JAGA 1B71A 3M3YL 2LCQA 2Y0SP 2JA8L 4JAFA 2M6OA 3S1QL 3KYVA 2C6BA 4A3GL 5IP9L 2APOB 3HOXL 3H9BA 3RZOL 2E2HL 1R0HA 3S2DL 3SS2A 4C3HL 3H3VM 4AI3A 2PYAA 1F4LA 3JR7A 3K7AL 3LWQB 2GMGA 3B0AB 2C6AA 1OWBA 3HOWL 1Y1WL 3GTPL 1VCXA 1RYTA 4AR6A 3KYWA 1PFVA 5MFPA 3HOZL 2K2DA 5C3EL 2HR5A 4RXNA 4A3FL 3S1ML 3I4ML 4POFA 3P2AA 3PO2L 2M4VA 1LTLA 2JI2A 3A44A 3GTKL 4Y52L 2EY4E 3RZDL 1R9TL 3HOYL 5EINC 2VL6A 4A3JL 1WCML 2PPTA 1Y1VL 2A68D 3GTQL 1LKMA 4LHNA 1SFOL 4AHZA 5MGNA 1B2JA 3PIP1 4AHWA 3LWOB
chains in the Genus database with same CATH topology
2HVYC 3LWPB 3LWRB 3HAXC 3HJWB 2EY4E 2AUSB 2APOB 3MQKB 3HJYB 2AQCA 3LWVB 3LWOB 3LWQB 2RFKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HVY C;  3LWP B;  3LWR B;  3HAX C;  3HJW B;  2EY4 E;  2AUS B;  2APO B;  3MQK B;  3HJY B;  2AQC A;  3LWV B;  3LWO B;  3LWQ B;  2RFK B; 
#chains in the Genus database with same CATH topology
 5GAG c;  3IU3 I;  1YUZ A;  1C09 A;  1TWC L;  7RXN A;  4B8C D;  5GAD c;  2NVX L;  2J9U B;  5C44 L;  3HAX C;  1WJV A;  2ERJ A;  8RXN A;  2XJU A;  1PFY A;  4AYB P;  3PL5 A;  4AI2 A;  1NXE A;  4A3D L;  4A3K L;  2PSM C;  3H0G L;  2PVX A;  3LPE B;  2XJR A;  5C4J L;  5JVG 1;  5JVH 1;  1YK5 A;  2XJT A;  1YV1 A;  3LNL A;  3S17 L;  1IU5 A;  5AI2 A;  5RXN A;  4AI0 A;  3S1N L;  2O5J D;  3HKZ P;  1RB9 A;  2NVT L;  1E8J A;  2XJV A;  3PIO 1;  2KKD A;  2RFK B;  2YU9 L;  2HVY C;  1T9Q A;  3WWL A;  3VPB E;  2QL0 A;  4C3I L;  2M6P A;  1BFY A;  4AR4 A;  4XGH A;  3FDJ A;  5IP7 L;  4E6Y A;  1IRN A;  4ME3 A;  5C4X L;  4C2M 1;  1DX8 A;  5MLC 3;  4X6A L;  4TVM A;  4A3I L;  6RXN A;  5DM6 1;  1PFU A;  1VZI A;  1R0G A;  3FKI L;  1BRF A;  2WB1 P;  4V19 6;  5AI3 A;  5M5X L;  3GTL L;  1I3Q L;  3LWR B;  4AHX A;  4K9F A;  3NFP I;  3QQC E;  4ZN1 B;  1QYB A;  5M5W L;  4A3L L;  4BY7 L;  1T9O A;  1H7V A;  1VZG A;  2E2J L;  3B08 B;  2KN9 A;  1NNQ A;  2R93 L;  4QIW P;  5MF6 A;  3KYX A;  4AHY A;  4WFN 1;  3HJY B;  3WWN B;  1FHM A;  3S14 L;  2PVE A;  4BY1 L;  3MQK B;  2MS3 A;  4A93 L;  2Z3Q B;  4AI1 A;  3GTJ L;  1S30 A;  4BBR L;  4G6B A;  4A3E L;  5H1S c;  1CAD A;  1YUX A;  3QVD A;  5K2M E;  3KYU A;  2NVY L;  2JI1 A;  3LWV B;  1QCV A;  4ZN3 B;  1IRO A;  3S1R L;  2A6E D;  1TWG L;  5IYB L;  3HJW B;  3P8B A;  4A3B L;  3PZA A;  4TPU A;  1I50 L;  1NXG A;  2DSX A;  5FJ8 L;  3S15 L;  2JI3 A;  2ERS A;  1IU6 A;  4AR5 A;  5DM7 1;  2CR8 A;  2R7Z L;  4BBS L;  2JA7 L;  3PO3 L;  2BE5 D;  1RYQ A;  2Z3R B;  4YWM A;  3HOV L;  3H99 A;  1SMU A;  3S16 L;  1IW7 D;  4A3M L;  2JA5 L;  3J7Y 1;  2RDV A;  1JYB A;  2V0E A;  2NYD A;  1QQT A;  2E2I L;  2M4Y A;  1CAA A;  5MFZ A;  2PMZ P;  2XJP A;  1TWA L;  1YK4 A;  1T9P A;  5M3M L;  3GTO L;  4UY8 1;  2XJQ A;  2AQC A;  1R0I A;  4BXX L;  4GS7 D;  1S24 A;  1RDG A;  1B2O A;  1K83 L;  2WAQ P;  1BE7 A;  1ZRP A;  5EIO C;  3J7Z 1;  3M4O L;  5M3F L;  3I4N L;  1DVB A;  2A69 D;  1B13 A;  1BQ8 A;  2XJS A;  2CKC A;  4XXB B;  3MSU A;  2VUM L;  5IYD L;  2JA6 L;  1RDV A;  3GTM L;  3RYG A;  1RWD A;  3RZT A;  3CQZ L;  3ZG6 A;  3LWP B;  2AYJ A;  5M5Y L;  4U67 1;  5IYC L;  3K35 A;  3HOU L;  4Y7N L;  5FLM L;  3H9C A;  5AN9 H;  3PKJ A;  4JAD A;  1SMW A;  4YWL A;  1ODH A;  2CKA A;  3MPS A;  4POG A;  3H97 A;  1FHH A;  2V0F A;  1TWH L;  2L0Z A;  1R0F A;  1S2Z A;  5GAH c;  1VZH A;  3KYY A;  3PKI A;  3S2H L;  5IY0 A;  2H12 A;  4AR3 A;  2B63 L;  3PWF A;  4JAE A;  1I6H L;  1P7P A;  3GTG L;  1R0J A;  1LKO A;  2R92 L;  5GAE c;  1LKP A;  2B5I D;  2NVQ L;  2AUS B;  4LHL A;  2ZIX A;  1PZX A;  2V3B B;  4C3J L;  1BQ9 A;  1Z92 B;  1PFW A;  1TWF L;  3RZ6 A;  1OWC A;  1SMM A;  4A3C L;  2A6H D;  4JAG A;  1B71 A;  3M3Y L;  2LCQ A;  2Y0S P;  2JA8 L;  4JAF A;  2M6O A;  3S1Q L;  3KYV A;  2C6B A;  4A3G L;  5IP9 L;  2APO B;  3HOX L;  3H9B A;  3RZO L;  2E2H L;  1R0H A;  3S2D L;  3SS2 A;  4C3H L;  3H3V M;  4AI3 A;  2PYA A;  1F4L A;  3JR7 A;  3K7A L;  3LWQ B;  2GMG A;  3B0A B;  2C6A A;  1OWB A;  3HOW L;  1Y1W L;  3GTP L;  1VCX A;  1RYT A;  4AR6 A;  3KYW A;  1PFV A;  5MFP A;  3HOZ L;  2K2D A;  5C3E L;  2HR5 A;  4RXN A;  4A3F L;  3S1M L;  3I4M L;  4POF A;  3P2A A;  3PO2 L;  2M4V A;  1LTL A;  2JI2 A;  3A44 A;  3GTK L;  4Y52 L;  2EY4 E;  3RZD L;  1R9T L;  3HOY L;  5EIN C;  2VL6 A;  4A3J L;  1WCM L;  2PPT A;  1Y1V L;  2A68 D;  3GTQ L;  1LKM A;  4LHN A;  1SFO L;  4AHZ A;  5MGN A;  1B2J A;  3PIP 1;  4AHW A;  3LWO B; 
#chains in the Genus database with same CATH homology
 2HVY C;  3LWP B;  3LWR B;  3HAX C;  3HJW B;  2EY4 E;  2AUS B;  2APO B;  3MQK B;  3HJY B;  2AQC A;  3LWV B;  3LWO B;  3LWQ B;  2RFK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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