3P71C

Crystal structure of the complex of lcmt-1 and pp2a
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
303
structure length
303
Chain Sequence
DEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPHVTRRTPDYFL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structural Basis for Tight Control of PP2A Methylation and Function by LCMT-1.
pubmed doi rcsb
molecule tags Transferase/hydrolase
source organism Homo sapiens
molecule keywords Leucine carboxyl methyltransferase 1
total genus 110
structure length 303
sequence length 303
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2010-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3p71C00
2O8GA 1II7A 1S95A 4ZVZA 3QFMA 4WWLA 2WDCA 4V0VA 1QFCA 2DFJA 3H67A 1OI8A 4M0VA 2A22A 3N5UA 4YKEA 4UWQA 1HPUA 4FBKA 1V73A 4I5LC 2USHA 3H64A 3C5WC 2P6BA 2HYPA 1KBPA 5B8IA 1IT6A 2Z72A 2IE3C 3PSNA 4B2OA 4Q7FA 3RL3A 4H2BA 4TUIA 3AV0A 4LACC 4ORBA 2AHDA 5JJTA 2BQ8X 4JA9A 2CV9A 1JK7A 3E7BA 5HPEA 1S3MA 1XM7A 1NNWA 3H63A 3PSOA 4V0XA 4DT2A 3CK2A 3HVQA 1UF3A 4H2GA 4MP0A 1USHA 2WDFA 5IOHA 5GTUA 3IVDA 1Z2WA 5C1VA 1OIDA 4DHLA 4FBWA 4DSYA 1HO5A 2BCDA 5JPEA 3QFOA 2IAEC 2KKNA 5DNYA 4ORCA 2NYMC 3H60A 1SU1A 4HD0A 2ZBMA 3DSDA 3H62B 1S3LA 3AUZA 3H68A 4ZX2A 2QFRA 2GJUA 4NZVA 2WDDA 2WDEA 3EGHA 3THOB 4FBQA 2Z06A 4KKZA 1WAO1 4J6OA 1S8EA 4H1YP 2NXFA 3P71C 4XPNA 2YVTA 3GVEA 1WARA 3IB7A 4H2FA 4FCXA 1M63A 3FGAC 4O4KA 1G5BA 3ICFA 1FJMA 2Q8UA 3EGGA 4ORAA 5J28A 4UT3B 5JPFA 2HY1A 1U32A 4O24A 3IVEA 1W24A 2JOGA 2HYOA 2XMOA 3IB8A 3H61A 4OR9A 4UT2A 3ZU0A 3K7WC 3H66A 3QFKA 4I5NC 4IYPC 3T1IA 4LTYA 2IE4C 4UT3A 1T70A 3V4YA 1HP1A 3LL8A 3QFNA 4LU9A 2BDXA 1S70A 4H1SA 2R17A 1S3NA 1OIEA 3H69A 3KBPA 3TGHA 4TUGA 3E7AA 4IL1A 3RL4A 3RQZA 4V0WA 3ZTVA 1T71A 4MOYA 2O8AA 3RL5A 1QHWA 4JA7A 1MF8A 4MOVA 3C9FA 2NYLC 3JYFA 3THNA 1Z2XA 2NPPC 2Z1AA 4KBPA 3QG5C 4F0ZA 4O5GA 5INBA 2QJCA 1UTEA 4O43A 1XZWA 1TCOA 3DW8C 2QFPA 5EQVA 5F3WA 3DSCA 4H2IA 4G9JA 3K7VC 1AUIA
chains in the Genus database with same CATH superfamily
2O8GA 1II7A 1S95A 4ZVZA 3QFMA 4WWLA 2WDCA 4V0VA 1QFCA 2DFJA 3H67A 1OI8A 4M0VA 2A22A 3N5UA 4YKEA 4UWQA 1HPUA 4FBKA 1V73A 4I5LC 2USHA 3H64A 2DXLA 3C5WC 2P6BA 2HYPA 1KBPA 5B8IA 1IT6A 2Z72A 2IE3C 3PSNA 4B2OA 4Q7FA 3RL3A 4H2BA 4TUIA 3AV0A 4LACC 4ORBA 2AHDA 5JJTA 2BQ8X 4JA9A 2CV9A 1JK7A 3E7BA 5HPEA 1S3MA 1XM7A 1NNWA 3H63A 3PSOA 4V0XA 4DT2A 3CK2A 3HVQA 1UF3A 4H2GA 4MP0A 1USHA 2WDFA 5IOHA 5GTUA 3IVDA 1Z2WA 5C1VA 1OIDA 4DHLA 4FBWA 4DSYA 1HO5A 2BCDA 5JPEA 3QFOA 2IAEC 2KKNA 5DNYA 4ORCA 2NYMC 3H60A 1SU1A 4HD0A 2ZBMA 3DSDA 3H62B 1S3LA 3AUZA 3H68A 4ZX2A 2QFRA 2GJUA 4NZVA 2WDDA 2WDEA 3D03A 3EGHA 3THOB 4FBQA 2Z06A 2ZOAA 1WAO1 4KKZA 4J6OA 1S8EA 4H1YP 3E0JA 2DXNA 2NXFA 3P71C 4XPNA 2YVTA 3GVEA 1WARA 3IB7A 4H2FA 4FCXA 1M63A 2ZO9B 3FGAC 4O4KA 1G5BA 3ICFA 1FJMA 2Q8UA 3EGGA 4ORAA 5J28A 4UT3B 5JPFA 2HY1A 1U32A 4O24A 3IVEA 1W24A 2JOGA 2HYOA 2XMOA 3IB8A 3H61A 4OR9A 4UT2A 3ZU0A 3K7WC 3H66A 3QFKA 4I5NC 4IYPC 3T1IA 4LTYA 2IE4C 4UT3A 1T70A 3V4YA 2YEQA 1HP1A 3LL8A 3QFNA 4LU9A 2BDXA 1S70A 4H1SA 2R17A 1S3NA 1OIEA 3H69A 3KBPA 3TGHA 4TUGA 3E7AA 4IL1A 3RL4A 3RQZA 4V0WA 3ZTVA 1T71A 4MOYA 2O8AA 3RL5A 1QHWA 4JA7A 1MF8A 4MOVA 3C9FA 2NYLC 3JYFA 3THNA 1Z2XA 2NPPC 2Z1AA 4KBPA 3QG5C 4F0ZA 4O5GA 5INBA 2QJCA 1UTEA 4O43A 1XZWA 1TCOA 3DW8C 2QFPA 5EQVA 5F3WA 3DSCA 4H2IA 4G9JA 3FLOA 3K7VC 1AUIA
chains in the Genus database with same CATH topology
2O8GA 1II7A 1S95A 4ZVZA 3QFMA 4WWLA 2WDCA 4V0VA 1QFCA 2DFJA 3H67A 1OI8A 4M0VA 2A22A 3N5UA 4YKEA 4UWQA 1HPUA 4FBKA 1V73A 4I5LC 2USHA 3H64A 2DXLA 3C5WC 2P6BA 2HYPA 1KBPA 5B8IA 1IT6A 2Z72A 2IE3C 3PSNA 4B2OA 4Q7FA 3RL3A 4H2BA 4TUIA 3AV0A 4LACC 4ORBA 2AHDA 5JJTA 2BQ8X 4JA9A 2CV9A 1JK7A 3E7BA 5HPEA 1S3MA 1XM7A 1NNWA 3H63A 3PSOA 4V0XA 4DT2A 3CK2A 3HVQA 1UF3A 4H2GA 4MP0A 1USHA 2WDFA 5IOHA 5GTUA 3IVDA 1Z2WA 5C1VA 1OIDA 4DHLA 4FBWA 4DSYA 1HO5A 2BCDA 5JPEA 3QFOA 2IAEC 2KKNA 5DNYA 4ORCA 2NYMC 3H60A 1SU1A 4HD0A 2ZBMA 3DSDA 3H62B 1S3LA 3AUZA 3H68A 4ZX2A 2QFRA 2GJUA 4NZVA 2WDDA 2WDEA 3D03A 3EGHA 3THOB 4FBQA 2Z06A 2ZOAA 1WAO1 4KKZA 4J6OA 1S8EA 4H1YP 3E0JA 2DXNA 2NXFA 3P71C 4XPNA 2YVTA 3GVEA 1WARA 3IB7A 4H2FA 4FCXA 1M63A 2ZO9B 3FGAC 4O4KA 1G5BA 3ICFA 1FJMA 2Q8UA 3EGGA 4ORAA 5J28A 4UT3B 5JPFA 2HY1A 1U32A 4O24A 3IVEA 1W24A 2JOGA 2HYOA 2XMOA 3IB8A 3H61A 4OR9A 4UT2A 3ZU0A 3K7WC 3H66A 3QFKA 4I5NC 4IYPC 3T1IA 4LTYA 2IE4C 4UT3A 1T70A 3V4YA 2YEQA 1HP1A 3LL8A 3QFNA 4LU9A 2BDXA 1S70A 4H1SA 2R17A 1S3NA 1OIEA 3H69A 3KBPA 3TGHA 4TUGA 3E7AA 4IL1A 3RL4A 3RQZA 4V0WA 3ZTVA 1T71A 4MOYA 2O8AA 3RL5A 1QHWA 4JA7A 1MF8A 4MOVA 3C9FA 2NYLC 3JYFA 3THNA 1Z2XA 2NPPC 2Z1AA 4KBPA 3QG5C 4F0ZA 4O5GA 5INBA 2QJCA 1UTEA 4O43A 1XZWA 1TCOA 3DW8C 2QFPA 5EQVA 5F3WA 3DSCA 4H2IA 4G9JA 3FLOA 3K7VC 1AUIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O8G A;  1II7 A;  1S95 A;  4ZVZ A;  3QFM A;  4WWL A;  2WDC A;  4V0V A;  1QFC A;  2DFJ A;  3H67 A;  1OI8 A;  4M0V A;  2A22 A;  3N5U A;  4YKE A;  4UWQ A;  1HPU A;  4FBK A;  1V73 A;  4I5L C;  2USH A;  3H64 A;  3C5W C;  2P6B A;  2HYP A;  1KBP A;  5B8I A;  1IT6 A;  2Z72 A;  2IE3 C;  3PSN A;  4B2O A;  4Q7F A;  3RL3 A;  4H2B A;  4TUI A;  3AV0 A;  4LAC C;  4ORB A;  2AHD A;  5JJT A;  2BQ8 X;  4JA9 A;  2CV9 A;  1JK7 A;  3E7B A;  5HPE A;  1S3M A;  1XM7 A;  1NNW A;  3H63 A;  3PSO A;  4V0X A;  4DT2 A;  3CK2 A;  3HVQ A;  1UF3 A;  4H2G A;  4MP0 A;  1USH A;  2WDF A;  5IOH A;  5GTU A;  3IVD A;  1Z2W A;  5C1V A;  1OID A;  4DHL A;  4FBW A;  4DSY A;  1HO5 A;  2BCD A;  5JPE A;  3QFO A;  2IAE C;  2KKN A;  5DNY A;  4ORC A;  2NYM C;  3H60 A;  1SU1 A;  4HD0 A;  2ZBM A;  3DSD A;  3H62 B;  1S3L A;  3AUZ A;  3H68 A;  4ZX2 A;  2QFR A;  2GJU A;  4NZV A;  2WDD A;  2WDE A;  3EGH A;  3THO B;  4FBQ A;  2Z06 A;  4KKZ A;  1WAO 1;  4J6O A;  1S8E A;  4H1Y P;  2NXF A;  3P71 C;  4XPN A;  2YVT A;  3GVE A;  1WAR A;  3IB7 A;  4H2F A;  4FCX A;  1M63 A;  3FGA C;  4O4K A;  1G5B A;  3ICF A;  1FJM A;  2Q8U A;  3EGG A;  4ORA A;  5J28 A;  4UT3 B;  5JPF A;  2HY1 A;  1U32 A;  4O24 A;  3IVE A;  1W24 A;  2JOG A;  2HYO A;  2XMO A;  3IB8 A;  3H61 A;  4OR9 A;  4UT2 A;  3ZU0 A;  3K7W C;  3H66 A;  3QFK A;  4I5N C;  4IYP C;  3T1I A;  4LTY A;  2IE4 C;  4UT3 A;  1T70 A;  3V4Y A;  1HP1 A;  3LL8 A;  3QFN A;  4LU9 A;  2BDX A;  1S70 A;  4H1S A;  2R17 A;  1S3N A;  1OIE A;  3H69 A;  3KBP A;  3TGH A;  4TUG A;  3E7A A;  4IL1 A;  3RL4 A;  3RQZ A;  4V0W A;  3ZTV A;  1T71 A;  4MOY A;  2O8A A;  3RL5 A;  1QHW A;  4JA7 A;  1MF8 A;  4MOV A;  3C9F A;  2NYL C;  3JYF A;  3THN A;  1Z2X A;  2NPP C;  2Z1A A;  4KBP A;  3QG5 C;  4F0Z A;  4O5G A;  5INB A;  2QJC A;  1UTE A;  4O43 A;  1XZW A;  1TCO A;  3DW8 C;  2QFP A;  5EQV A;  5F3W A;  3DSC A;  4H2I A;  4G9J A;  3K7V C;  1AUI A; 
#chains in the Genus database with same CATH topology
 2O8G A;  1II7 A;  1S95 A;  4ZVZ A;  3QFM A;  4WWL A;  2WDC A;  4V0V A;  1QFC A;  2DFJ A;  3H67 A;  1OI8 A;  4M0V A;  2A22 A;  3N5U A;  4YKE A;  4UWQ A;  1HPU A;  4FBK A;  1V73 A;  4I5L C;  2USH A;  3H64 A;  2DXL A;  3C5W C;  2P6B A;  2HYP A;  1KBP A;  5B8I A;  1IT6 A;  2Z72 A;  2IE3 C;  3PSN A;  4B2O A;  4Q7F A;  3RL3 A;  4H2B A;  4TUI A;  3AV0 A;  4LAC C;  4ORB A;  2AHD A;  5JJT A;  2BQ8 X;  4JA9 A;  2CV9 A;  1JK7 A;  3E7B A;  5HPE A;  1S3M A;  1XM7 A;  1NNW A;  3H63 A;  3PSO A;  4V0X A;  4DT2 A;  3CK2 A;  3HVQ A;  1UF3 A;  4H2G A;  4MP0 A;  1USH A;  2WDF A;  5IOH A;  5GTU A;  3IVD A;  1Z2W A;  5C1V A;  1OID A;  4DHL A;  4FBW A;  4DSY A;  1HO5 A;  2BCD A;  5JPE A;  3QFO A;  2IAE C;  2KKN A;  5DNY A;  4ORC A;  2NYM C;  3H60 A;  1SU1 A;  4HD0 A;  2ZBM A;  3DSD A;  3H62 B;  1S3L A;  3AUZ A;  3H68 A;  4ZX2 A;  2QFR A;  2GJU A;  4NZV A;  2WDD A;  2WDE A;  3D03 A;  3EGH A;  3THO B;  4FBQ A;  2Z06 A;  2ZOA A;  1WAO 1;  4KKZ A;  4J6O A;  1S8E A;  4H1Y P;  3E0J A;  2DXN A;  2NXF A;  3P71 C;  4XPN A;  2YVT A;  3GVE A;  1WAR A;  3IB7 A;  4H2F A;  4FCX A;  1M63 A;  2ZO9 B;  3FGA C;  4O4K A;  1G5B A;  3ICF A;  1FJM A;  2Q8U A;  3EGG A;  4ORA A;  5J28 A;  4UT3 B;  5JPF A;  2HY1 A;  1U32 A;  4O24 A;  3IVE A;  1W24 A;  2JOG A;  2HYO A;  2XMO A;  3IB8 A;  3H61 A;  4OR9 A;  4UT2 A;  3ZU0 A;  3K7W C;  3H66 A;  3QFK A;  4I5N C;  4IYP C;  3T1I A;  4LTY A;  2IE4 C;  4UT3 A;  1T70 A;  3V4Y A;  2YEQ A;  1HP1 A;  3LL8 A;  3QFN A;  4LU9 A;  2BDX A;  1S70 A;  4H1S A;  2R17 A;  1S3N A;  1OIE A;  3H69 A;  3KBP A;  3TGH A;  4TUG A;  3E7A A;  4IL1 A;  3RL4 A;  3RQZ A;  4V0W A;  3ZTV A;  1T71 A;  4MOY A;  2O8A A;  3RL5 A;  1QHW A;  4JA7 A;  1MF8 A;  4MOV A;  3C9F A;  2NYL C;  3JYF A;  3THN A;  1Z2X A;  2NPP C;  2Z1A A;  4KBP A;  3QG5 C;  4F0Z A;  4O5G A;  5INB A;  2QJC A;  1UTE A;  4O43 A;  1XZW A;  1TCO A;  3DW8 C;  2QFP A;  5EQV A;  5F3W A;  3DSC A;  4H2I A;  4G9J A;  3FLO A;  3K7V C;  1AUI A; 
#chains in the Genus database with same CATH homology
 2O8G A;  1II7 A;  1S95 A;  4ZVZ A;  3QFM A;  4WWL A;  2WDC A;  4V0V A;  1QFC A;  2DFJ A;  3H67 A;  1OI8 A;  4M0V A;  2A22 A;  3N5U A;  4YKE A;  4UWQ A;  1HPU A;  4FBK A;  1V73 A;  4I5L C;  2USH A;  3H64 A;  2DXL A;  3C5W C;  2P6B A;  2HYP A;  1KBP A;  5B8I A;  1IT6 A;  2Z72 A;  2IE3 C;  3PSN A;  4B2O A;  4Q7F A;  3RL3 A;  4H2B A;  4TUI A;  3AV0 A;  4LAC C;  4ORB A;  2AHD A;  5JJT A;  2BQ8 X;  4JA9 A;  2CV9 A;  1JK7 A;  3E7B A;  5HPE A;  1S3M A;  1XM7 A;  1NNW A;  3H63 A;  3PSO A;  4V0X A;  4DT2 A;  3CK2 A;  3HVQ A;  1UF3 A;  4H2G A;  4MP0 A;  1USH A;  2WDF A;  5IOH A;  5GTU A;  3IVD A;  1Z2W A;  5C1V A;  1OID A;  4DHL A;  4FBW A;  4DSY A;  1HO5 A;  2BCD A;  5JPE A;  3QFO A;  2IAE C;  2KKN A;  5DNY A;  4ORC A;  2NYM C;  3H60 A;  1SU1 A;  4HD0 A;  2ZBM A;  3DSD A;  3H62 B;  1S3L A;  3AUZ A;  3H68 A;  4ZX2 A;  2QFR A;  2GJU A;  4NZV A;  2WDD A;  2WDE A;  3D03 A;  3EGH A;  3THO B;  4FBQ A;  2Z06 A;  2ZOA A;  1WAO 1;  4KKZ A;  4J6O A;  1S8E A;  4H1Y P;  3E0J A;  2DXN A;  2NXF A;  3P71 C;  4XPN A;  2YVT A;  3GVE A;  1WAR A;  3IB7 A;  4H2F A;  4FCX A;  1M63 A;  2ZO9 B;  3FGA C;  4O4K A;  1G5B A;  3ICF A;  1FJM A;  2Q8U A;  3EGG A;  4ORA A;  5J28 A;  4UT3 B;  5JPF A;  2HY1 A;  1U32 A;  4O24 A;  3IVE A;  1W24 A;  2JOG A;  2HYO A;  2XMO A;  3IB8 A;  3H61 A;  4OR9 A;  4UT2 A;  3ZU0 A;  3K7W C;  3H66 A;  3QFK A;  4I5N C;  4IYP C;  3T1I A;  4LTY A;  2IE4 C;  4UT3 A;  1T70 A;  3V4Y A;  2YEQ A;  1HP1 A;  3LL8 A;  3QFN A;  4LU9 A;  2BDX A;  1S70 A;  4H1S A;  2R17 A;  1S3N A;  1OIE A;  3H69 A;  3KBP A;  3TGH A;  4TUG A;  3E7A A;  4IL1 A;  3RL4 A;  3RQZ A;  4V0W A;  3ZTV A;  1T71 A;  4MOY A;  2O8A A;  3RL5 A;  1QHW A;  4JA7 A;  1MF8 A;  4MOV A;  3C9F A;  2NYL C;  3JYF A;  3THN A;  1Z2X A;  2NPP C;  2Z1A A;  4KBP A;  3QG5 C;  4F0Z A;  4O5G A;  5INB A;  2QJC A;  1UTE A;  4O43 A;  1XZW A;  1TCO A;  3DW8 C;  2QFP A;  5EQV A;  5F3W A;  3DSC A;  4H2I A;  4G9J A;  3FLO A;  3K7V C;  1AUI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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