3P71C

Crystal structure of the complex of lcmt-1 and pp2a
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
303
structure length
303
Chain Sequence
DEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPHVTRRTPDYFL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structural Basis for Tight Control of PP2A Methylation and Function by LCMT-1.
pubmed doi rcsb
molecule tags Transferase/hydrolase
source organism Homo sapiens
molecule keywords Leucine carboxyl methyltransferase 1
total genus 110
structure length 303
sequence length 303
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2010-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3p71C00
2NYMC 4ORAA 2QJCA 2O8AA 4H2FA 1TCOA 3ZU0A 5JJTA 4WWLA 1UTEA 1S3NA 4ZVZA 1S3MA 4IYPC 2WDFA 5HPEA 3RQZA 4ORCA 3RL4A 4H1SA 4H1YP 1WARA 3H69A 3K7WC 2O8GA 1SU1A 4F0ZA 3H63A 4M0VA 1KBPA 1WAO1 1S3LA 2IE3C 3QG5C 5J28A 1QHWA 3H66A 1S95A 1Z2WA 2ZBMA 2IE4C 3ICFA 4JA7A 4MOVA 2Z1AA 4OR9A 2A22A 2USHA 2Z72A 2HYPA 2BQ8X 3IB7A 4LU9A 3T1IA 1T70A 1HP1A 4Q7FA 1V73A 3EGHA 4MOYA 2QFPA 4XPNA 3H68A 1M63A 1MF8A 1Z2XA 4HD0A 3P71C 1W24A 4G9JA 3QFOA 2KKNA 5INBA 3E7BA 3V4YA 3THNA 1QFCA 3AUZA 5JPEA 4H2BA 1OI8A 3E7AA 4O24A 3JYFA 3TGHA 1IT6A 2R17A 3RL3A 4V0XA 1XM7A 4DHLA 3EGGA 3LL8A 4I5NC 2AHDA 2NYLC 4JA9A 5EQVA 2BDXA 3FGAC 1OIEA 2QFRA 3QFMA 1S8EA 2JOGA 2WDDA 4O43A 3C5WC 4I5LC 3IVDA 1U32A 1USHA 2XMOA 5B8IA 1OIDA 3QFKA 4IL1A 2HYOA 4NZVA 5JPFA 3THOB 4DSYA 1G5BA 4KBPA 4FBWA 4J6OA 4ORBA 3HVQA 5GTUA 3PSOA 3DW8C 2GJUA 2Q8UA 4TUGA 3RL5A 4LACC 1II7A 2NPPC 4H2IA 4H2GA 4UT2A 4MP0A 3DSDA 2HY1A 1XZWA 1HO5A 3H60A 3H61A 3C9FA 3DSCA 2DFJA 3QFNA 3H64A 3H62B 4YKEA 5F3WA 1FJMA 3PSNA 4DT2A 1AUIA 2IAEC 4V0WA 2NXFA 4LTYA 1UF3A 1T71A 4UWQA 3H67A 3N5UA 3KBPA 4B2OA 5DNYA 1JK7A 2P6BA 4FBQA 5IOHA 2Z06A 4V0VA 1NNWA 4O4KA 3IB8A 4ZX2A 2BCDA 2CV9A 5C1VA 4UT3A 2WDCA 4FBKA 4KKZA 3IVEA 3CK2A 4FCXA 4UT3B 3AV0A 1S70A 4O5GA 2YVTA 1HPUA 3GVEA 4TUIA 3ZTVA 3K7VC 2WDEA
chains in the Genus database with same CATH superfamily
2NYMC 4ORAA 2QJCA 2O8AA 4H2FA 1TCOA 3ZU0A 5JJTA 4WWLA 1UTEA 1S3NA 4ZVZA 1S3MA 4IYPC 2WDFA 5HPEA 3RQZA 4ORCA 3RL4A 2YEQA 4H1SA 4H1YP 1WARA 3H69A 3K7WC 2O8GA 1SU1A 4F0ZA 3H63A 4M0VA 1KBPA 1WAO1 1S3LA 2IE3C 3QG5C 5J28A 1QHWA 3H66A 1S95A 1Z2WA 2DXNA 2ZBMA 2IE4C 3ICFA 4JA7A 4MOVA 2Z1AA 4OR9A 2A22A 2USHA 2Z72A 2HYPA 2BQ8X 2ZO9B 3IB7A 4LU9A 3T1IA 1T70A 1HP1A 4Q7FA 1V73A 3EGHA 4MOYA 2QFPA 4XPNA 3H68A 1M63A 1MF8A 1Z2XA 3E0JA 4HD0A 3P71C 1W24A 4G9JA 3QFOA 2KKNA 5INBA 3E7BA 3V4YA 3THNA 1QFCA 3AUZA 5JPEA 4H2BA 1OI8A 3E7AA 4O24A 3JYFA 3TGHA 1IT6A 2R17A 3RL3A 4V0XA 1XM7A 4DHLA 3EGGA 3LL8A 4I5NC 2AHDA 2NYLC 4JA9A 5EQVA 2BDXA 3FGAC 2DXLA 1OIEA 2QFRA 3QFMA 1S8EA 2JOGA 2WDDA 4O43A 3C5WC 4I5LC 3IVDA 1U32A 1USHA 2XMOA 5B8IA 1OIDA 3QFKA 4IL1A 2HYOA 4NZVA 5JPFA 3THOB 4DSYA 1G5BA 4KBPA 4FBWA 4J6OA 4ORBA 3HVQA 3FLOA 3PSOA 3D03A 5GTUA 3DW8C 2GJUA 2Q8UA 2ZOAA 4TUGA 3RL5A 4LACC 1II7A 2NPPC 4H2IA 4H2GA 4UT2A 4MP0A 3DSDA 2HY1A 1XZWA 1HO5A 3H60A 3H61A 3C9FA 3DSCA 2DFJA 3QFNA 3H64A 3H62B 4YKEA 5F3WA 1FJMA 3PSNA 4DT2A 1AUIA 2IAEC 4V0WA 2NXFA 4LTYA 1UF3A 1T71A 4UWQA 3H67A 3N5UA 3KBPA 4B2OA 5DNYA 1JK7A 2P6BA 4FBQA 5IOHA 2Z06A 4V0VA 1NNWA 4O4KA 3IB8A 4ZX2A 2BCDA 2CV9A 5C1VA 4UT3A 2WDCA 4FBKA 4KKZA 3IVEA 3CK2A 4FCXA 4UT3B 3AV0A 1S70A 4O5GA 2YVTA 1HPUA 3GVEA 4TUIA 3ZTVA 3K7VC 2WDEA
chains in the Genus database with same CATH topology
2NYMC 4ORAA 2QJCA 2O8AA 4H2FA 1TCOA 3ZU0A 5JJTA 4WWLA 1UTEA 1S3NA 4ZVZA 1S3MA 4IYPC 2WDFA 5HPEA 3RQZA 4ORCA 3RL4A 2YEQA 4H1SA 4H1YP 1WARA 3H69A 3K7WC 2O8GA 1SU1A 4F0ZA 3H63A 4M0VA 1KBPA 1WAO1 1S3LA 2IE3C 3QG5C 5J28A 1QHWA 3H66A 1S95A 1Z2WA 2DXNA 2ZBMA 2IE4C 3ICFA 4JA7A 4MOVA 2Z1AA 4OR9A 2A22A 2USHA 2Z72A 2HYPA 2BQ8X 2ZO9B 3IB7A 4LU9A 3T1IA 1T70A 1HP1A 4Q7FA 1V73A 3EGHA 4MOYA 2QFPA 4XPNA 3H68A 1M63A 1MF8A 1Z2XA 3E0JA 4HD0A 3P71C 1W24A 4G9JA 3QFOA 2KKNA 5INBA 3E7BA 3V4YA 3THNA 1QFCA 3AUZA 5JPEA 4H2BA 1OI8A 3E7AA 4O24A 3JYFA 3TGHA 1IT6A 2R17A 3RL3A 4V0XA 1XM7A 4DHLA 3EGGA 3LL8A 4I5NC 2AHDA 2NYLC 4JA9A 5EQVA 2BDXA 3FGAC 2DXLA 1OIEA 2QFRA 3QFMA 1S8EA 2JOGA 2WDDA 4O43A 3C5WC 4I5LC 3IVDA 1U32A 1USHA 2XMOA 5B8IA 1OIDA 3QFKA 4IL1A 2HYOA 4NZVA 5JPFA 3THOB 4DSYA 1G5BA 4KBPA 4FBWA 4J6OA 4ORBA 3HVQA 3FLOA 3PSOA 3D03A 5GTUA 3DW8C 2GJUA 2Q8UA 2ZOAA 4TUGA 3RL5A 4LACC 1II7A 2NPPC 4H2IA 4H2GA 4UT2A 4MP0A 3DSDA 2HY1A 1XZWA 1HO5A 3H60A 3H61A 3C9FA 3DSCA 2DFJA 3QFNA 3H64A 3H62B 4YKEA 5F3WA 1FJMA 3PSNA 4DT2A 1AUIA 2IAEC 4V0WA 2NXFA 4LTYA 1UF3A 1T71A 4UWQA 3H67A 3N5UA 3KBPA 4B2OA 5DNYA 1JK7A 2P6BA 4FBQA 5IOHA 2Z06A 4V0VA 1NNWA 4O4KA 3IB8A 4ZX2A 2BCDA 2CV9A 5C1VA 4UT3A 2WDCA 4FBKA 4KKZA 3IVEA 3CK2A 4FCXA 4UT3B 3AV0A 1S70A 4O5GA 2YVTA 1HPUA 3GVEA 4TUIA 3ZTVA 3K7VC 2WDEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NYM C;  4ORA A;  2QJC A;  2O8A A;  4H2F A;  1TCO A;  3ZU0 A;  5JJT A;  4WWL A;  1UTE A;  1S3N A;  4ZVZ A;  1S3M A;  4IYP C;  2WDF A;  5HPE A;  3RQZ A;  4ORC A;  3RL4 A;  4H1S A;  4H1Y P;  1WAR A;  3H69 A;  3K7W C;  2O8G A;  1SU1 A;  4F0Z A;  3H63 A;  4M0V A;  1KBP A;  1WAO 1;  1S3L A;  2IE3 C;  3QG5 C;  5J28 A;  1QHW A;  3H66 A;  1S95 A;  1Z2W A;  2ZBM A;  2IE4 C;  3ICF A;  4JA7 A;  4MOV A;  2Z1A A;  4OR9 A;  2A22 A;  2USH A;  2Z72 A;  2HYP A;  2BQ8 X;  3IB7 A;  4LU9 A;  3T1I A;  1T70 A;  1HP1 A;  4Q7F A;  1V73 A;  3EGH A;  4MOY A;  2QFP A;  4XPN A;  3H68 A;  1M63 A;  1MF8 A;  1Z2X A;  4HD0 A;  3P71 C;  1W24 A;  4G9J A;  3QFO A;  2KKN A;  5INB A;  3E7B A;  3V4Y A;  3THN A;  1QFC A;  3AUZ A;  5JPE A;  4H2B A;  1OI8 A;  3E7A A;  4O24 A;  3JYF A;  3TGH A;  1IT6 A;  2R17 A;  3RL3 A;  4V0X A;  1XM7 A;  4DHL A;  3EGG A;  3LL8 A;  4I5N C;  2AHD A;  2NYL C;  4JA9 A;  5EQV A;  2BDX A;  3FGA C;  1OIE A;  2QFR A;  3QFM A;  1S8E A;  2JOG A;  2WDD A;  4O43 A;  3C5W C;  4I5L C;  3IVD A;  1U32 A;  1USH A;  2XMO A;  5B8I A;  1OID A;  3QFK A;  4IL1 A;  2HYO A;  4NZV A;  5JPF A;  3THO B;  4DSY A;  1G5B A;  4KBP A;  4FBW A;  4J6O A;  4ORB A;  3HVQ A;  5GTU A;  3PSO A;  3DW8 C;  2GJU A;  2Q8U A;  4TUG A;  3RL5 A;  4LAC C;  1II7 A;  2NPP C;  4H2I A;  4H2G A;  4UT2 A;  4MP0 A;  3DSD A;  2HY1 A;  1XZW A;  1HO5 A;  3H60 A;  3H61 A;  3C9F A;  3DSC A;  2DFJ A;  3QFN A;  3H64 A;  3H62 B;  4YKE A;  5F3W A;  1FJM A;  3PSN A;  4DT2 A;  1AUI A;  2IAE C;  4V0W A;  2NXF A;  4LTY A;  1UF3 A;  1T71 A;  4UWQ A;  3H67 A;  3N5U A;  3KBP A;  4B2O A;  5DNY A;  1JK7 A;  2P6B A;  4FBQ A;  5IOH A;  2Z06 A;  4V0V A;  1NNW A;  4O4K A;  3IB8 A;  4ZX2 A;  2BCD A;  2CV9 A;  5C1V A;  4UT3 A;  2WDC A;  4FBK A;  4KKZ A;  3IVE A;  3CK2 A;  4FCX A;  4UT3 B;  3AV0 A;  1S70 A;  4O5G A;  2YVT A;  1HPU A;  3GVE A;  4TUI A;  3ZTV A;  3K7V C;  2WDE A; 
#chains in the Genus database with same CATH topology
 2NYM C;  4ORA A;  2QJC A;  2O8A A;  4H2F A;  1TCO A;  3ZU0 A;  5JJT A;  4WWL A;  1UTE A;  1S3N A;  4ZVZ A;  1S3M A;  4IYP C;  2WDF A;  5HPE A;  3RQZ A;  4ORC A;  3RL4 A;  2YEQ A;  4H1S A;  4H1Y P;  1WAR A;  3H69 A;  3K7W C;  2O8G A;  1SU1 A;  4F0Z A;  3H63 A;  4M0V A;  1KBP A;  1WAO 1;  1S3L A;  2IE3 C;  3QG5 C;  5J28 A;  1QHW A;  3H66 A;  1S95 A;  1Z2W A;  2DXN A;  2ZBM A;  2IE4 C;  3ICF A;  4JA7 A;  4MOV A;  2Z1A A;  4OR9 A;  2A22 A;  2USH A;  2Z72 A;  2HYP A;  2BQ8 X;  2ZO9 B;  3IB7 A;  4LU9 A;  3T1I A;  1T70 A;  1HP1 A;  4Q7F A;  1V73 A;  3EGH A;  4MOY A;  2QFP A;  4XPN A;  3H68 A;  1M63 A;  1MF8 A;  1Z2X A;  3E0J A;  4HD0 A;  3P71 C;  1W24 A;  4G9J A;  3QFO A;  2KKN A;  5INB A;  3E7B A;  3V4Y A;  3THN A;  1QFC A;  3AUZ A;  5JPE A;  4H2B A;  1OI8 A;  3E7A A;  4O24 A;  3JYF A;  3TGH A;  1IT6 A;  2R17 A;  3RL3 A;  4V0X A;  1XM7 A;  4DHL A;  3EGG A;  3LL8 A;  4I5N C;  2AHD A;  2NYL C;  4JA9 A;  5EQV A;  2BDX A;  3FGA C;  2DXL A;  1OIE A;  2QFR A;  3QFM A;  1S8E A;  2JOG A;  2WDD A;  4O43 A;  3C5W C;  4I5L C;  3IVD A;  1U32 A;  1USH A;  2XMO A;  5B8I A;  1OID A;  3QFK A;  4IL1 A;  2HYO A;  4NZV A;  5JPF A;  3THO B;  4DSY A;  1G5B A;  4KBP A;  4FBW A;  4J6O A;  4ORB A;  3HVQ A;  3FLO A;  3PSO A;  3D03 A;  5GTU A;  3DW8 C;  2GJU A;  2Q8U A;  2ZOA A;  4TUG A;  3RL5 A;  4LAC C;  1II7 A;  2NPP C;  4H2I A;  4H2G A;  4UT2 A;  4MP0 A;  3DSD A;  2HY1 A;  1XZW A;  1HO5 A;  3H60 A;  3H61 A;  3C9F A;  3DSC A;  2DFJ A;  3QFN A;  3H64 A;  3H62 B;  4YKE A;  5F3W A;  1FJM A;  3PSN A;  4DT2 A;  1AUI A;  2IAE C;  4V0W A;  2NXF A;  4LTY A;  1UF3 A;  1T71 A;  4UWQ A;  3H67 A;  3N5U A;  3KBP A;  4B2O A;  5DNY A;  1JK7 A;  2P6B A;  4FBQ A;  5IOH A;  2Z06 A;  4V0V A;  1NNW A;  4O4K A;  3IB8 A;  4ZX2 A;  2BCD A;  2CV9 A;  5C1V A;  4UT3 A;  2WDC A;  4FBK A;  4KKZ A;  3IVE A;  3CK2 A;  4FCX A;  4UT3 B;  3AV0 A;  1S70 A;  4O5G A;  2YVT A;  1HPU A;  3GVE A;  4TUI A;  3ZTV A;  3K7V C;  2WDE A; 
#chains in the Genus database with same CATH homology
 2NYM C;  4ORA A;  2QJC A;  2O8A A;  4H2F A;  1TCO A;  3ZU0 A;  5JJT A;  4WWL A;  1UTE A;  1S3N A;  4ZVZ A;  1S3M A;  4IYP C;  2WDF A;  5HPE A;  3RQZ A;  4ORC A;  3RL4 A;  2YEQ A;  4H1S A;  4H1Y P;  1WAR A;  3H69 A;  3K7W C;  2O8G A;  1SU1 A;  4F0Z A;  3H63 A;  4M0V A;  1KBP A;  1WAO 1;  1S3L A;  2IE3 C;  3QG5 C;  5J28 A;  1QHW A;  3H66 A;  1S95 A;  1Z2W A;  2DXN A;  2ZBM A;  2IE4 C;  3ICF A;  4JA7 A;  4MOV A;  2Z1A A;  4OR9 A;  2A22 A;  2USH A;  2Z72 A;  2HYP A;  2BQ8 X;  2ZO9 B;  3IB7 A;  4LU9 A;  3T1I A;  1T70 A;  1HP1 A;  4Q7F A;  1V73 A;  3EGH A;  4MOY A;  2QFP A;  4XPN A;  3H68 A;  1M63 A;  1MF8 A;  1Z2X A;  3E0J A;  4HD0 A;  3P71 C;  1W24 A;  4G9J A;  3QFO A;  2KKN A;  5INB A;  3E7B A;  3V4Y A;  3THN A;  1QFC A;  3AUZ A;  5JPE A;  4H2B A;  1OI8 A;  3E7A A;  4O24 A;  3JYF A;  3TGH A;  1IT6 A;  2R17 A;  3RL3 A;  4V0X A;  1XM7 A;  4DHL A;  3EGG A;  3LL8 A;  4I5N C;  2AHD A;  2NYL C;  4JA9 A;  5EQV A;  2BDX A;  3FGA C;  2DXL A;  1OIE A;  2QFR A;  3QFM A;  1S8E A;  2JOG A;  2WDD A;  4O43 A;  3C5W C;  4I5L C;  3IVD A;  1U32 A;  1USH A;  2XMO A;  5B8I A;  1OID A;  3QFK A;  4IL1 A;  2HYO A;  4NZV A;  5JPF A;  3THO B;  4DSY A;  1G5B A;  4KBP A;  4FBW A;  4J6O A;  4ORB A;  3HVQ A;  3FLO A;  3PSO A;  3D03 A;  5GTU A;  3DW8 C;  2GJU A;  2Q8U A;  2ZOA A;  4TUG A;  3RL5 A;  4LAC C;  1II7 A;  2NPP C;  4H2I A;  4H2G A;  4UT2 A;  4MP0 A;  3DSD A;  2HY1 A;  1XZW A;  1HO5 A;  3H60 A;  3H61 A;  3C9F A;  3DSC A;  2DFJ A;  3QFN A;  3H64 A;  3H62 B;  4YKE A;  5F3W A;  1FJM A;  3PSN A;  4DT2 A;  1AUI A;  2IAE C;  4V0W A;  2NXF A;  4LTY A;  1UF3 A;  1T71 A;  4UWQ A;  3H67 A;  3N5U A;  3KBP A;  4B2O A;  5DNY A;  1JK7 A;  2P6B A;  4FBQ A;  5IOH A;  2Z06 A;  4V0V A;  1NNW A;  4O4K A;  3IB8 A;  4ZX2 A;  2BCD A;  2CV9 A;  5C1V A;  4UT3 A;  2WDC A;  4FBK A;  4KKZ A;  3IVE A;  3CK2 A;  4FCX A;  4UT3 B;  3AV0 A;  1S70 A;  4O5G A;  2YVT A;  1HPU A;  3GVE A;  4TUI A;  3ZTV A;  3K7V C;  2WDE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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