3PIO1

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
53
structure length
53
Chain Sequence
AKDGPRIIVKMESSAGTGFYYTTTKNRRNTQAKLELKKYDPVAKKHVVFREKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 1
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
1 PF00471 Ribosomal_L33 Ribosomal protein L33
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.120 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 3pio100
5GADc 5GAHc 5GAGc 5GAEc 5DM71 5DM61 3J7Y1 4V196 3PIO1 5JVG1 4UY81 5MLC3 5H1Sc 4U671 4WFN1 3J7Z1 5JVH1 3PIP1
chains in the Genus database with same CATH superfamily
2LCQA 3RZDL 3HJWB 4B8CD 5GADc 3MSUA 1TWFL 3LNLA 3GTGL 1T9OA 3S2DL 1SFOL 2E2HL 2VL6A 2BE5D 3PKIA 3GTKL 2AUSB 2JI1A 4A3KL 2ERSA 5GAGc 4AI3A 5IYDL 4JADA 4ZN1B 5M5WL 3RZOL 3HOWL 2APOB 4BY7L 2A68D 5EIOC 1VZIA 1SMUA 1Z92B 3KYUA 3S1QL 4LHLA 1BFYA 2EY4E 1PZXA 2WAQP 2B63L 3LWVB 2C6BA 4C3HL 1NXEA 4ME3A 3GTPL 4UY81 1QCVA 5AI3A 3PIP1 4ZN3B 5M5XL 5M5YL 1FHHA 1TWGL 1R9TL 2AQCA 1SMMA 3LPEB 3PIO1 3HOVL 2PVXA 1IW7D 2DSXA 3I4NL 1IU6A 1CADA 3QVDA 2QL0A 1PFUA 3HOYL 3QQCE 5C4JL 1OWCA 4E6YA 2Z3RB 3PL5A 1B13A 2AYJA 5DM71 5FLML 3H0GL 5H1Sc 1R0IA 3HJYB 4XXBB 3A44A 2XJVA 4YWMA 3LWQB 3S14L 1RYTA 2A6HD 2L0ZA 4Y7NL 2JA7L 5K2ME 2M6PA 4A3FL 5M3FL 1RWDA 4GS7D 4A3JL 5MF6A 4A3EL 4A3BL 2R93L 5JVG1 3H97A 1QYBA 2Z3QB 1BE7A 3PZAA 1VZGA 3B0AB 5IP9L 2PMZP 4BY1L 1T9PA 4POFA 4C2M1 4AI2A 4AHZA 4YWLA 1T9QA 5AI2A 2O5JD 3GTOL 1I50L 2YU9L 4A3IL 1RYQA 3H9CA 1SMWA 2PVEA 2J9UB 3FDJA 4JAEA 2B5ID 1RDVA 4A3GL 2A6ED 1BQ9A 2JA5L 3KYVA 3SS2A 1H7VA 3P8BA 2NVYL 3S1NL 3MPSA 3RZ6A 2XJSA 2KKDA 2XJRA 1NXGA 1R0HA 5AN9H 4A3CL 1OWBA 3KYWA 5C4XL 4AR3A 1I6HL 4RXNA 1QQTA 4BXXL 4BBSL 3WWLA 1ODHA 3PO3L 3P2AA 1R0GA 2R7ZL 3WWNB 5C44L 4AYBP 3H3VM 3H99A 4AR6A 2H12A 1ZRPA 3S2HL 1YK5A 2KN9A 4U671 1TWCL 4XGHA 2JA8L 5DM61 3S16L 1IRNA 2HVYC 2NVQL 4V196 3LWRB 3H9BA 1Y1WL 2M4VA 2WB1P 2XJQA 4A3ML 4TPUA 4QIWP 4AI1A 1VZHA 3VPBE 4AHXA 5JVH1 5GAHc 2PSMC 5RXNA 6RXNA 1WCML 1TWHL 4A93L 3KYXA 3GTJL 2JA6L 2CKCA 3HKZP 1K83L 3PWFA 1S2ZA 3PKJA 3RYGA 3ZG6A 1LKOA 3HOUL 2HR5A 4POGA 2CR8A 2RFKB 1LKMA 1S24A 5IP7L 1IROA 3K35A 4C3IL 1DX8A 1TWAL 3HAXC 2C6AA 5MGNA 1PFVA 1F4LA 2RDVA 2Y0SP 4JAFA 2NVXL 1LTLA 1R0JA 1B2OA 4C3JL 1PFWA 4AR4A 4AHWA 1BRFA 4LHNA 1PFYA 1YUZA 1P7PA 1RB9A 3FKIL 2V0EA 5EINC 5IYCL 2XJUA 2NVTL 5C3EL 1NNQA 3HOXL 3NFPI 1DVBA 1E8JA 4JAGA 5MFZA 4A3DL 1CAAA 3KYYA 4AI0A 3S17L 3RZTA 2JI3A 2MS3A 2M4YA 1I3QL 4K9FA 7RXNA 4G6BA 3M3YL 2M6OA 3LWPB 3GTML 1C09A 4AHYA 5M3ML 3S15L 3IU3I 1YK4A 3CQZL 2GMGA 1IU5A 2VUML 3LWOB 1LKPA 1Y1VL 4X6AL 5IYBL 2V0FA 3MQKB 3GTQL 1B71A 2PPTA 4Y52L 1BQ8A 2JI2A 2E2JL 1FHMA 1YV1A 3JR7A 1B2JA 2XJTA 3I4ML 5IY0A 2A69D 3PO2L 1WJVA 2R92L 5FJ8L 4TVMA 1R0FA 4WFN1 8RXNA 3GTLL 3S1ML 3S1RL 2K2DA 1YUXA 2CKAA 3M4OL 5MLC3 3J7Z1 3K7AL 2PYAA 1VCXA 2V3BB 4BBRL 4A3LL 2NYDA 2ERJA 1S30A 4AR5A 5MFPA 3J7Y1 2XJPA 5GAEc 3B08B 2E2IL 2ZIXA 3HOZL 1RDGA 1JYBA
chains in the Genus database with same CATH topology
3P2AA 1R0GA 2LCQA 5DM71 4LHNA 3WWNB 5H1Sc 1R0IA 1YUZA 4B8CD 1RB9A 5GADc 4XXBB 3A44A 3MSUA 2XJVA 2V0EA 2H12A 3LNLA 4AR6A 5EINC 2XJUA 1ZRPA 1NNQA 4YWMA 3NFPI 1DVBA 1E8JA 1T9OA 1RYTA 2A6HD 4JAGA 2L0ZA 1YK5A 2KN9A 4U671 2VL6A 2BE5D 5MFZA 1CAAA 5K2ME 3KYYA 3PKIA 2M6PA 4XGHA 4AI0A 5DM61 3RZTA 2JI3A 1RWDA 2MS3A 2JI1A 2M4YA 2ERSA 4K9FA 5GAGc 7RXNA 4G6BA 4GS7D 4AI3A 2M6OA 5MF6A 1IRNA 4JADA 1C09A 4ZN1B 4AHYA 4V196 5JVG1 1QYBA 2Z3QB 3IU3I 1BE7A 1YK4A 2M4VA 2XJQA 3PZAA 1VZGA 3B0AB 4TPUA 4AI1A 1VZHA 3VPBE 4AHXA 2A68D 1T9PA 5JVH1 2GMGA 4POFA 1IU5A 5EIOC 1VZIA 5GAHc 2PSMC 1LKPA 4AI2A 4AHZA 1SMUA 1Z92B 3KYUA 5RXNA 2V0FA 4LHLA 1BFYA 4YWLA 6RXNA 1T9QA 5AI2A 2O5JD 3KYXA 1B71A 2CKCA 2PPTA 2C6BA 3PWFA 1BQ8A 1RYQA 1NXEA 1SMWA 1S2ZA 3PKJA 4ME3A 2PVEA 3RYGA 3ZG6A 4UY81 2JI2A 1QCVA 5AI3A 1FHMA 3PIP1 4ZN3B 2J9UB 1LKOA 1YV1A 2B5ID 4JAEA 1B2JA 2HR5A 1RDVA 2XJTA 4POGA 1FHHA 2CR8A 2A69D 5IY0A 1WJVA 1LKMA 1SMMA 2A6ED 1BQ9A 4TVMA 3LPEB 1R0FA 3PIO1 3KYVA 1S24A 3SS2A 2PVXA 1H7VA 1IROA 4WFN1 8RXNA 1IW7D 3P8BA 2DSXA 3MPSA 3RZ6A 3K35A 1IU6A 1DX8A 2XJSA 2K2DA 1CADA 1YUXA 2KKDA 2XJRA 1NXGA 1R0HA 5AN9H 3QVDA 2C6AA 2QL0A 1OWBA 2CKAA 3KYWA 3QQCE 2PYAA 1VCXA 2V3BB 5MGNA 5MLC3 2RDVA 3J7Z1 4JAFA 1LTLA 4AR3A 1OWCA 4E6YA 2NYDA 2ERJA 2Z3RB 1R0JA 1B2OA 1S30A 1B13A 4AR5A 4RXNA 4AR4A 5MFPA 4AHWA 2XJPA 5GAEc 3B08B 2AYJA 3J7Y1 1BRFA 2ZIXA 3WWLA 1RDGA 1ODHA 1JYBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GAD c;  5GAH c;  5GAG c;  5GAE c;  5DM7 1;  5DM6 1;  3J7Y 1;  4V19 6;  3PIO 1;  5JVG 1;  4UY8 1;  5MLC 3;  5H1S c;  4U67 1;  4WFN 1;  3J7Z 1;  5JVH 1;  3PIP 1; 
#chains in the Genus database with same CATH topology
 2LCQ A;  3RZD L;  3HJW B;  4B8C D;  5GAD c;  3MSU A;  1TWF L;  3LNL A;  3GTG L;  1T9O A;  3S2D L;  1SFO L;  2E2H L;  2VL6 A;  2BE5 D;  3PKI A;  3GTK L;  2AUS B;  2JI1 A;  4A3K L;  2ERS A;  5GAG c;  4AI3 A;  5IYD L;  4JAD A;  4ZN1 B;  5M5W L;  3RZO L;  3HOW L;  2APO B;  4BY7 L;  2A68 D;  5EIO C;  1VZI A;  1SMU A;  1Z92 B;  3KYU A;  3S1Q L;  4LHL A;  1BFY A;  2EY4 E;  1PZX A;  2WAQ P;  2B63 L;  3LWV B;  2C6B A;  4C3H L;  1NXE A;  4ME3 A;  3GTP L;  4UY8 1;  1QCV A;  5AI3 A;  3PIP 1;  4ZN3 B;  5M5X L;  5M5Y L;  1FHH A;  1TWG L;  1R9T L;  2AQC A;  1SMM A;  3LPE B;  3PIO 1;  3HOV L;  2PVX A;  1IW7 D;  2DSX A;  3I4N L;  1IU6 A;  1CAD A;  3QVD A;  2QL0 A;  1PFU A;  3HOY L;  3QQC E;  5C4J L;  1OWC A;  4E6Y A;  2Z3R B;  3PL5 A;  1B13 A;  2AYJ A;  5DM7 1;  5FLM L;  3H0G L;  5H1S c;  1R0I A;  3HJY B;  4XXB B;  3A44 A;  2XJV A;  4YWM A;  3LWQ B;  3S14 L;  1RYT A;  2A6H D;  2L0Z A;  4Y7N L;  2JA7 L;  5K2M E;  2M6P A;  4A3F L;  5M3F L;  1RWD A;  4GS7 D;  4A3J L;  5MF6 A;  4A3E L;  4A3B L;  2R93 L;  5JVG 1;  3H97 A;  1QYB A;  2Z3Q B;  1BE7 A;  3PZA A;  1VZG A;  3B0A B;  5IP9 L;  2PMZ P;  4BY1 L;  1T9P A;  4POF A;  4C2M 1;  4AI2 A;  4AHZ A;  4YWL A;  1T9Q A;  5AI2 A;  2O5J D;  3GTO L;  1I50 L;  2YU9 L;  4A3I L;  1RYQ A;  3H9C A;  1SMW A;  2PVE A;  2J9U B;  3FDJ A;  4JAE A;  2B5I D;  1RDV A;  4A3G L;  2A6E D;  1BQ9 A;  2JA5 L;  3KYV A;  3SS2 A;  1H7V A;  3P8B A;  2NVY L;  3S1N L;  3MPS A;  3RZ6 A;  2XJS A;  2KKD A;  2XJR A;  1NXG A;  1R0H A;  5AN9 H;  4A3C L;  1OWB A;  3KYW A;  5C4X L;  4AR3 A;  1I6H L;  4RXN A;  1QQT A;  4BXX L;  4BBS L;  3WWL A;  1ODH A;  3PO3 L;  3P2A A;  1R0G A;  2R7Z L;  3WWN B;  5C44 L;  4AYB P;  3H3V M;  3H99 A;  4AR6 A;  2H12 A;  1ZRP A;  3S2H L;  1YK5 A;  2KN9 A;  4U67 1;  1TWC L;  4XGH A;  2JA8 L;  5DM6 1;  3S16 L;  1IRN A;  2HVY C;  2NVQ L;  4V19 6;  3LWR B;  3H9B A;  1Y1W L;  2M4V A;  2WB1 P;  2XJQ A;  4A3M L;  4TPU A;  4QIW P;  4AI1 A;  1VZH A;  3VPB E;  4AHX A;  5JVH 1;  5GAH c;  2PSM C;  5RXN A;  6RXN A;  1WCM L;  1TWH L;  4A93 L;  3KYX A;  3GTJ L;  2JA6 L;  2CKC A;  3HKZ P;  1K83 L;  3PWF A;  1S2Z A;  3PKJ A;  3RYG A;  3ZG6 A;  1LKO A;  3HOU L;  2HR5 A;  4POG A;  2CR8 A;  2RFK B;  1LKM A;  1S24 A;  5IP7 L;  1IRO A;  3K35 A;  4C3I L;  1DX8 A;  1TWA L;  3HAX C;  2C6A A;  5MGN A;  1PFV A;  1F4L A;  2RDV A;  2Y0S P;  4JAF A;  2NVX L;  1LTL A;  1R0J A;  1B2O A;  4C3J L;  1PFW A;  4AR4 A;  4AHW A;  1BRF A;  4LHN A;  1PFY A;  1YUZ A;  1P7P A;  1RB9 A;  3FKI L;  2V0E A;  5EIN C;  5IYC L;  2XJU A;  2NVT L;  5C3E L;  1NNQ A;  3HOX L;  3NFP I;  1DVB A;  1E8J A;  4JAG A;  5MFZ A;  4A3D L;  1CAA A;  3KYY A;  4AI0 A;  3S17 L;  3RZT A;  2JI3 A;  2MS3 A;  2M4Y A;  1I3Q L;  4K9F A;  7RXN A;  4G6B A;  3M3Y L;  2M6O A;  3LWP B;  3GTM L;  1C09 A;  4AHY A;  5M3M L;  3S15 L;  3IU3 I;  1YK4 A;  3CQZ L;  2GMG A;  1IU5 A;  2VUM L;  3LWO B;  1LKP A;  1Y1V L;  4X6A L;  5IYB L;  2V0F A;  3MQK B;  3GTQ L;  1B71 A;  2PPT A;  4Y52 L;  1BQ8 A;  2JI2 A;  2E2J L;  1FHM A;  1YV1 A;  3JR7 A;  1B2J A;  2XJT A;  3I4M L;  5IY0 A;  2A69 D;  3PO2 L;  1WJV A;  2R92 L;  5FJ8 L;  4TVM A;  1R0F A;  4WFN 1;  8RXN A;  3GTL L;  3S1M L;  3S1R L;  2K2D A;  1YUX A;  2CKA A;  3M4O L;  5MLC 3;  3J7Z 1;  3K7A L;  2PYA A;  1VCX A;  2V3B B;  4BBR L;  4A3L L;  2NYD A;  2ERJ A;  1S30 A;  4AR5 A;  5MFP A;  3J7Y 1;  2XJP A;  5GAE c;  3B08 B;  2E2I L;  2ZIX A;  3HOZ L;  1RDG A;  1JYB A; 
#chains in the Genus database with same CATH homology
 3P2A A;  1R0G A;  2LCQ A;  5DM7 1;  4LHN A;  3WWN B;  5H1S c;  1R0I A;  1YUZ A;  4B8C D;  1RB9 A;  5GAD c;  4XXB B;  3A44 A;  3MSU A;  2XJV A;  2V0E A;  2H12 A;  3LNL A;  4AR6 A;  5EIN C;  2XJU A;  1ZRP A;  1NNQ A;  4YWM A;  3NFP I;  1DVB A;  1E8J A;  1T9O A;  1RYT A;  2A6H D;  4JAG A;  2L0Z A;  1YK5 A;  2KN9 A;  4U67 1;  2VL6 A;  2BE5 D;  5MFZ A;  1CAA A;  5K2M E;  3KYY A;  3PKI A;  2M6P A;  4XGH A;  4AI0 A;  5DM6 1;  3RZT A;  2JI3 A;  1RWD A;  2MS3 A;  2JI1 A;  2M4Y A;  2ERS A;  4K9F A;  5GAG c;  7RXN A;  4G6B A;  4GS7 D;  4AI3 A;  2M6O A;  5MF6 A;  1IRN A;  4JAD A;  1C09 A;  4ZN1 B;  4AHY A;  4V19 6;  5JVG 1;  1QYB A;  2Z3Q B;  3IU3 I;  1BE7 A;  1YK4 A;  2M4V A;  2XJQ A;  3PZA A;  1VZG A;  3B0A B;  4TPU A;  4AI1 A;  1VZH A;  3VPB E;  4AHX A;  2A68 D;  1T9P A;  5JVH 1;  2GMG A;  4POF A;  1IU5 A;  5EIO C;  1VZI A;  5GAH c;  2PSM C;  1LKP A;  4AI2 A;  4AHZ A;  1SMU A;  1Z92 B;  3KYU A;  5RXN A;  2V0F A;  4LHL A;  1BFY A;  4YWL A;  6RXN A;  1T9Q A;  5AI2 A;  2O5J D;  3KYX A;  1B71 A;  2CKC A;  2PPT A;  2C6B A;  3PWF A;  1BQ8 A;  1RYQ A;  1NXE A;  1SMW A;  1S2Z A;  3PKJ A;  4ME3 A;  2PVE A;  3RYG A;  3ZG6 A;  4UY8 1;  2JI2 A;  1QCV A;  5AI3 A;  1FHM A;  3PIP 1;  4ZN3 B;  2J9U B;  1LKO A;  1YV1 A;  2B5I D;  4JAE A;  1B2J A;  2HR5 A;  1RDV A;  2XJT A;  4POG A;  1FHH A;  2CR8 A;  2A69 D;  5IY0 A;  1WJV A;  1LKM A;  1SMM A;  2A6E D;  1BQ9 A;  4TVM A;  3LPE B;  1R0F A;  3PIO 1;  3KYV A;  1S24 A;  3SS2 A;  2PVX A;  1H7V A;  1IRO A;  4WFN 1;  8RXN A;  1IW7 D;  3P8B A;  2DSX A;  3MPS A;  3RZ6 A;  3K35 A;  1IU6 A;  1DX8 A;  2XJS A;  2K2D A;  1CAD A;  1YUX A;  2KKD A;  2XJR A;  1NXG A;  1R0H A;  5AN9 H;  3QVD A;  2C6A A;  2QL0 A;  1OWB A;  2CKA A;  3KYW A;  3QQC E;  2PYA A;  1VCX A;  2V3B B;  5MGN A;  5MLC 3;  2RDV A;  3J7Z 1;  4JAF A;  1LTL A;  4AR3 A;  1OWC A;  4E6Y A;  2NYD A;  2ERJ A;  2Z3R B;  1R0J A;  1B2O A;  1S30 A;  1B13 A;  4AR5 A;  4RXN A;  4AR4 A;  5MFP A;  4AHW A;  2XJP A;  5GAE c;  3B08 B;  2AYJ A;  3J7Y 1;  1BRF A;  2ZIX A;  3WWL A;  1RDG A;  1ODH A;  1JYB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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