3PIP1

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
53
structure length
53
Chain Sequence
AKDGPRIIVKMESSAGTGFYYTTTKNRRNTQAKLELKKYDPVAKKHVVFREKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 5
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
1 PF00471 Ribosomal_L33 Ribosomal protein L33
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.120 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 3pip100
5GAHc 5MLC3 5GAGc 4V196 5DM61 5JVG1 4UY81 5GAEc 3J7Z1 3PIO1 3PIP1 5GADc 5JVH1 5H1Sc 4WFN1 5DM71 4U671 3J7Y1
chains in the Genus database with same CATH superfamily
3P2AA 1P7PA 4WFN1 2VUML 3GTGL 2E2JL 4AHXA 4Y7NL 4ZN1B 1QQTA 2R92L 1BQ8A 1LTLA 3S16L 3PO3L 2R93L 1SFOL 2XJRA 1B2JA 1OWBA 4AR3A 5DM71 2V0EA 1B71A 3H99A 3ZG6A 3HJWB 5GAHc 2PPTA 4JAEA 2R7ZL 3HOZL 3HOYL 1R0FA 1NNQA 4AYBP 2Z3QB 5IP7L 3LWVB 2JA6L 5MFZA 1K83L 3GTQL 3H9BA 5H1Sc 1BE7A 1WCML 3WWNB 4TVMA 2JI3A 4BY1L 1T9PA 2PVEA 2A68D 1FHMA 2ERJA 3RYGA 2B63L 2KKDA 2V0FA 3GTLL 5C44L 4U671 1BFYA 2JA7L 2O5JD 4B8CD 4AHYA 1NXGA 1YK4A 2M6OA 5IP9L 4POFA 3J7Z1 3VPBE 1VZGA 1LKMA 5IYDL 4BY7L 1R0HA 2WB1P 1QYBA 4POGA 2YU9L 5FLML 1E8JA 5JVG1 3PZAA 2DSXA 4AI1A 2K2DA 3PO2L 1PFVA 2XJSA 1B2OA 3LPEB 7RXNA 5M3ML 3I4ML 3MQKB 2XJPA 1VZHA 2EY4E 1H7VA 3KYWA 5M5YL 5C3EL 2C6AA 4RXNA 2Y0SP 3A44A 4AR4A 5DM61 2CKCA 2M4YA 3RZDL 3S2DL 1I6HL 2JI1A 3GTJL 1PFWA 1IROA 3QVDA 4A3KL 3M3YL 1F4LA 4Y52L 1YK5A 2L0ZA 1RDGA 2HR5A 3CQZL 5JVH1 2C6BA 5AI2A 3RZ6A 1PFUA 3IU3I 3S1NL 5IY0A 4GS7D 1Y1VL 1PFYA 1ODHA 4E6YA 3MPSA 4UY81 1CADA 4JADA 3KYUA 2ZIXA 1WJVA 2A69D 4A3LL 4TPUA 4AI0A 1YUXA 1FHHA 4AI3A 3JR7A 5IYBL 3GTML 5GAGc 3GTKL 2NVYL 1RYTA 3HOWL 4A3ML 3K7AL 1C09A 3S15L 3S1ML 1IU6A 5IYCL 5M5XL 1RB9A 3NFPI 2J9UB 3HAXC 2PMZP 2E2HL 1DVBA 5GAEc 4X6AL 3B0AB 1TWHL 3PWFA 4A3IL 2AQCA 1IRNA 3KYYA 2PYAA 1ZRPA 5EINC 2JI2A 1Z92B 3I4NL 2GMGA 4YWLA 3S14L 4A93L 2M4VA 3LWRB 2XJQA 4G6BA 2HVYC 1R0IA 2NVQL 4YWMA 1LKOA 2AUSB 3K35A 3FDJA 1VZIA 3FKIL 4JAGA 3J7Y1 2M6PA 3RZOL 3PIO1 3HOXL 1S30A 1TWAL 3S17L 1JYBA 1BRFA 4C2M1 1QCVA 2VL6A 2KN9A 2AYJA 3P8BA 2PVXA 1RYQA 3LNLA 2XJVA 3WWLA 1R0GA 3KYXA 4AR6A 5MF6A 3HOVL 4QIWP 4AHWA 1S24A 2NYDA 4A3EL 3RZTA 4BBSL 5C4XL 1R0JA 1YUZA 1R9TL 3LWPB 3QQCE 4K9FA 2APOB 3GTPL 1I50L 5GADc 2CKAA 2WAQP 1VCXA 4XXBB 2RDVA 3PIP1 1SMMA 3B08B 1DX8A 1RWDA 4A3GL 4BXXL 5RXNA 4A3FL 5MFPA 3H0GL 4AHZA 3S2HL 2NVTL 3PL5A 2JA5L 1NXEA 1T9QA 4C3HL 4AR5A 1I3QL 2BE5D 1IU5A 1PZXA 4LHNA 3H97A 2QL0A 5C4JL 3HKZP 2B5ID 5AN9H 1BQ9A 1T9OA 5FJ8L 3PKIA 4LHLA 1OWCA 2CR8A 3SS2A 4A3DL 2LCQA 1TWFL 5MLC3 2XJUA 3HOUL 4A3CL 3H3VM 3S1RL 1LKPA 2MS3A 3KYVA 3MSUA 8RXNA 5MGNA 3LWQB 1B13A 4V196 1SMWA 2A6HD 2PSMC 5K2ME 3GTOL 4C3JL 2JA8L 3S1QL 2XJTA 5AI3A 1TWGL 1S2ZA 4A3BL 3LWOB 1RDVA 4XGHA 2H12A 2V3BB 2RFKB 2E2IL 3M4OL 4ZN3B 5M3FL 1Y1WL 2Z3RB 4BBRL 5EIOC 1YV1A 2A6ED 4ME3A 2ERSA 3HJYB 1SMUA 4C3IL 2NVXL 1TWCL 4JAFA 3H9CA 4AI2A 6RXNA 1IW7D 4A3JL 1CAAA 5M5WL 3PKJA
chains in the Genus database with same CATH topology
1NXEA 1E8JA 1T9QA 3NFPI 5JVG1 3P2AA 3PZAA 4AR5A 4WFN1 2DSXA 2BE5D 2J9UB 4AI1A 1IU5A 2K2DA 4LHNA 2QL0A 2XJSA 1DVBA 1B2OA 5GAEc 4AHXA 3B0AB 3LPEB 7RXNA 3PWFA 4ZN1B 2XJPA 2B5ID 5AN9H 1VZHA 1BQ9A 1IRNA 1BQ8A 1LTLA 2PYAA 3KYYA 1T9OA 1ZRPA 5EINC 2JI2A 1Z92B 1H7VA 2GMGA 3KYWA 4YWLA 3PKIA 2M4VA 4LHLA 1OWCA 2C6AA 2CR8A 2XJRA 2XJQA 4G6BA 1B2JA 4RXNA 3SS2A 1R0IA 1OWBA 4YWMA 2LCQA 4AR3A 1LKOA 3K35A 5DM71 3A44A 2V0EA 1B71A 5MLC3 2XJUA 1VZIA 4AR4A 5DM61 2CKCA 2M4YA 4JAGA 4POGA 3J7Y1 3ZG6A 2JI1A 2M6PA 2PPTA 4JAEA 5GAHc 1IROA 1LKPA 3QVDA 2MS3A 3KYVA 3PIO1 1YK5A 1S30A 2L0ZA 1RDGA 2HR5A 3MSUA 1R0FA 8RXNA 5JVH1 5MGNA 1JYBA 1NNQA 1B13A 1BRFA 2C6BA 2Z3QB 4V196 1QCVA 1SMWA 2A6HD 2PSMC 2VL6A 5AI2A 3RZ6A 5K2ME 3IU3I 2KN9A 3PKJA 5IY0A 5MFZA 4GS7D 2XJTA 3P8BA 2PVXA 1RYQA 3LNLA 2XJVA 5H1Sc 5AI3A 3WWLA 1ODHA 1R0GA 4E6YA 3MPSA 1BE7A 1S2ZA 3KYXA 4AR6A 1RDVA 5MF6A 4UY81 4XGHA 3WWNB 2H12A 2V3BB 4TVMA 2JI3A 4AHWA 1T9PA 2PVEA 1CADA 2A68D 1S24A 1FHMA 4ZN3B 4JADA 2ERJA 2NYDA 3KYUA 3RZTA 3RYGA 2KKDA 2Z3RB 2ZIXA 2V0FA 1YV1A 2A6ED 5EIOC 1R0JA 1WJVA 2A69D 4TPUA 4ME3A 1YUZA 2ERSA 1YUXA 4AI0A 1FHHA 4U671 1BFYA 4AI3A 2O5JD 3QQCE 4K9FA 1SMUA 5GADc 4B8CD 2CKAA 4JAFA 4AHYA 1NXGA 1VCXA 1YK4A 5GAGc 4XXBB 2RDVA 4AI2A 2M6OA 4POFA 3J7Z1 3PIP1 1SMMA 1RYTA 3B08B 1DX8A 1RWDA 6RXNA 3VPBE 1IW7D 1C09A 5RXNA 1VZGA 1LKMA 1R0HA 5MFPA 1CAAA 4AHZA 1IU6A 1QYBA 2AYJA 1RB9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GAH c;  5MLC 3;  5GAG c;  4V19 6;  5DM6 1;  5JVG 1;  4UY8 1;  5GAE c;  3J7Z 1;  3PIO 1;  3PIP 1;  5GAD c;  5JVH 1;  5H1S c;  4WFN 1;  5DM7 1;  4U67 1;  3J7Y 1; 
#chains in the Genus database with same CATH topology
 3P2A A;  1P7P A;  4WFN 1;  2VUM L;  3GTG L;  2E2J L;  4AHX A;  4Y7N L;  4ZN1 B;  1QQT A;  2R92 L;  1BQ8 A;  1LTL A;  3S16 L;  3PO3 L;  2R93 L;  1SFO L;  2XJR A;  1B2J A;  1OWB A;  4AR3 A;  5DM7 1;  2V0E A;  1B71 A;  3H99 A;  3ZG6 A;  3HJW B;  5GAH c;  2PPT A;  4JAE A;  2R7Z L;  3HOZ L;  3HOY L;  1R0F A;  1NNQ A;  4AYB P;  2Z3Q B;  5IP7 L;  3LWV B;  2JA6 L;  5MFZ A;  1K83 L;  3GTQ L;  3H9B A;  5H1S c;  1BE7 A;  1WCM L;  3WWN B;  4TVM A;  2JI3 A;  4BY1 L;  1T9P A;  2PVE A;  2A68 D;  1FHM A;  2ERJ A;  3RYG A;  2B63 L;  2KKD A;  2V0F A;  3GTL L;  5C44 L;  4U67 1;  1BFY A;  2JA7 L;  2O5J D;  4B8C D;  4AHY A;  1NXG A;  1YK4 A;  2M6O A;  5IP9 L;  4POF A;  3J7Z 1;  3VPB E;  1VZG A;  1LKM A;  5IYD L;  4BY7 L;  1R0H A;  2WB1 P;  1QYB A;  4POG A;  2YU9 L;  5FLM L;  1E8J A;  5JVG 1;  3PZA A;  2DSX A;  4AI1 A;  2K2D A;  3PO2 L;  1PFV A;  2XJS A;  1B2O A;  3LPE B;  7RXN A;  5M3M L;  3I4M L;  3MQK B;  2XJP A;  1VZH A;  2EY4 E;  1H7V A;  3KYW A;  5M5Y L;  5C3E L;  2C6A A;  4RXN A;  2Y0S P;  3A44 A;  4AR4 A;  5DM6 1;  2CKC A;  2M4Y A;  3RZD L;  3S2D L;  1I6H L;  2JI1 A;  3GTJ L;  1PFW A;  1IRO A;  3QVD A;  4A3K L;  3M3Y L;  1F4L A;  4Y52 L;  1YK5 A;  2L0Z A;  1RDG A;  2HR5 A;  3CQZ L;  5JVH 1;  2C6B A;  5AI2 A;  3RZ6 A;  1PFU A;  3IU3 I;  3S1N L;  5IY0 A;  4GS7 D;  1Y1V L;  1PFY A;  1ODH A;  4E6Y A;  3MPS A;  4UY8 1;  1CAD A;  4JAD A;  3KYU A;  2ZIX A;  1WJV A;  2A69 D;  4A3L L;  4TPU A;  4AI0 A;  1YUX A;  1FHH A;  4AI3 A;  3JR7 A;  5IYB L;  3GTM L;  5GAG c;  3GTK L;  2NVY L;  1RYT A;  3HOW L;  4A3M L;  3K7A L;  1C09 A;  3S15 L;  3S1M L;  1IU6 A;  5IYC L;  5M5X L;  1RB9 A;  3NFP I;  2J9U B;  3HAX C;  2PMZ P;  2E2H L;  1DVB A;  5GAE c;  4X6A L;  3B0A B;  1TWH L;  3PWF A;  4A3I L;  2AQC A;  1IRN A;  3KYY A;  2PYA A;  1ZRP A;  5EIN C;  2JI2 A;  1Z92 B;  3I4N L;  2GMG A;  4YWL A;  3S14 L;  4A93 L;  2M4V A;  3LWR B;  2XJQ A;  4G6B A;  2HVY C;  1R0I A;  2NVQ L;  4YWM A;  1LKO A;  2AUS B;  3K35 A;  3FDJ A;  1VZI A;  3FKI L;  4JAG A;  3J7Y 1;  2M6P A;  3RZO L;  3PIO 1;  3HOX L;  1S30 A;  1TWA L;  3S17 L;  1JYB A;  1BRF A;  4C2M 1;  1QCV A;  2VL6 A;  2KN9 A;  2AYJ A;  3P8B A;  2PVX A;  1RYQ A;  3LNL A;  2XJV A;  3WWL A;  1R0G A;  3KYX A;  4AR6 A;  5MF6 A;  3HOV L;  4QIW P;  4AHW A;  1S24 A;  2NYD A;  4A3E L;  3RZT A;  4BBS L;  5C4X L;  1R0J A;  1YUZ A;  1R9T L;  3LWP B;  3QQC E;  4K9F A;  2APO B;  3GTP L;  1I50 L;  5GAD c;  2CKA A;  2WAQ P;  1VCX A;  4XXB B;  2RDV A;  3PIP 1;  1SMM A;  3B08 B;  1DX8 A;  1RWD A;  4A3G L;  4BXX L;  5RXN A;  4A3F L;  5MFP A;  3H0G L;  4AHZ A;  3S2H L;  2NVT L;  3PL5 A;  2JA5 L;  1NXE A;  1T9Q A;  4C3H L;  4AR5 A;  1I3Q L;  2BE5 D;  1IU5 A;  1PZX A;  4LHN A;  3H97 A;  2QL0 A;  5C4J L;  3HKZ P;  2B5I D;  5AN9 H;  1BQ9 A;  1T9O A;  5FJ8 L;  3PKI A;  4LHL A;  1OWC A;  2CR8 A;  3SS2 A;  4A3D L;  2LCQ A;  1TWF L;  5MLC 3;  2XJU A;  3HOU L;  4A3C L;  3H3V M;  3S1R L;  1LKP A;  2MS3 A;  3KYV A;  3MSU A;  8RXN A;  5MGN A;  3LWQ B;  1B13 A;  4V19 6;  1SMW A;  2A6H D;  2PSM C;  5K2M E;  3GTO L;  4C3J L;  2JA8 L;  3S1Q L;  2XJT A;  5AI3 A;  1TWG L;  1S2Z A;  4A3B L;  3LWO B;  1RDV A;  4XGH A;  2H12 A;  2V3B B;  2RFK B;  2E2I L;  3M4O L;  4ZN3 B;  5M3F L;  1Y1W L;  2Z3R B;  4BBR L;  5EIO C;  1YV1 A;  2A6E D;  4ME3 A;  2ERS A;  3HJY B;  1SMU A;  4C3I L;  2NVX L;  1TWC L;  4JAF A;  3H9C A;  4AI2 A;  6RXN A;  1IW7 D;  4A3J L;  1CAA A;  5M5W L;  3PKJ A; 
#chains in the Genus database with same CATH homology
 1NXE A;  1E8J A;  1T9Q A;  3NFP I;  5JVG 1;  3P2A A;  3PZA A;  4AR5 A;  4WFN 1;  2DSX A;  2BE5 D;  2J9U B;  4AI1 A;  1IU5 A;  2K2D A;  4LHN A;  2QL0 A;  2XJS A;  1DVB A;  1B2O A;  5GAE c;  4AHX A;  3B0A B;  3LPE B;  7RXN A;  3PWF A;  4ZN1 B;  2XJP A;  2B5I D;  5AN9 H;  1VZH A;  1BQ9 A;  1IRN A;  1BQ8 A;  1LTL A;  2PYA A;  3KYY A;  1T9O A;  1ZRP A;  5EIN C;  2JI2 A;  1Z92 B;  1H7V A;  2GMG A;  3KYW A;  4YWL A;  3PKI A;  2M4V A;  4LHL A;  1OWC A;  2C6A A;  2CR8 A;  2XJR A;  2XJQ A;  4G6B A;  1B2J A;  4RXN A;  3SS2 A;  1R0I A;  1OWB A;  4YWM A;  2LCQ A;  4AR3 A;  1LKO A;  3K35 A;  5DM7 1;  3A44 A;  2V0E A;  1B71 A;  5MLC 3;  2XJU A;  1VZI A;  4AR4 A;  5DM6 1;  2CKC A;  2M4Y A;  4JAG A;  4POG A;  3J7Y 1;  3ZG6 A;  2JI1 A;  2M6P A;  2PPT A;  4JAE A;  5GAH c;  1IRO A;  1LKP A;  3QVD A;  2MS3 A;  3KYV A;  3PIO 1;  1YK5 A;  1S30 A;  2L0Z A;  1RDG A;  2HR5 A;  3MSU A;  1R0F A;  8RXN A;  5JVH 1;  5MGN A;  1JYB A;  1NNQ A;  1B13 A;  1BRF A;  2C6B A;  2Z3Q B;  4V19 6;  1QCV A;  1SMW A;  2A6H D;  2PSM C;  2VL6 A;  5AI2 A;  3RZ6 A;  5K2M E;  3IU3 I;  2KN9 A;  3PKJ A;  5IY0 A;  5MFZ A;  4GS7 D;  2XJT A;  3P8B A;  2PVX A;  1RYQ A;  3LNL A;  2XJV A;  5H1S c;  5AI3 A;  3WWL A;  1ODH A;  1R0G A;  4E6Y A;  3MPS A;  1BE7 A;  1S2Z A;  3KYX A;  4AR6 A;  1RDV A;  5MF6 A;  4UY8 1;  4XGH A;  3WWN B;  2H12 A;  2V3B B;  4TVM A;  2JI3 A;  4AHW A;  1T9P A;  2PVE A;  1CAD A;  2A68 D;  1S24 A;  1FHM A;  4ZN3 B;  4JAD A;  2ERJ A;  2NYD A;  3KYU A;  3RZT A;  3RYG A;  2KKD A;  2Z3R B;  2ZIX A;  2V0F A;  1YV1 A;  2A6E D;  5EIO C;  1R0J A;  1WJV A;  2A69 D;  4TPU A;  4ME3 A;  1YUZ A;  2ERS A;  1YUX A;  4AI0 A;  1FHH A;  4U67 1;  1BFY A;  4AI3 A;  2O5J D;  3QQC E;  4K9F A;  1SMU A;  5GAD c;  4B8C D;  2CKA A;  4JAF A;  4AHY A;  1NXG A;  1VCX A;  1YK4 A;  5GAG c;  4XXB B;  2RDV A;  4AI2 A;  2M6O A;  4POF A;  3J7Z 1;  3PIP 1;  1SMM A;  1RYT A;  3B08 B;  1DX8 A;  1RWD A;  6RXN A;  3VPB E;  1IW7 D;  1C09 A;  5RXN A;  1VZG A;  1LKM A;  1R0H A;  5MFP A;  1CAA A;  4AHZ A;  1IU6 A;  1QYB A;  2AYJ A;  1RB9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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