3RL3A

Rat metallophosphodiesterase mpped2
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
281
structure length
276
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Metallophosphoesterase MPPED2
total genus 86
structure length 276
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl3A00
1V73A 4O24A 1S8EA 2Q8UA 2P6BA 1W24A 2NYLC 3P71C 3H66A 1T70A 3AUZA 3PSNA 4H2IA 4H2BA 4HD0A 4UT3B 1QHWA 2CV9A 2WDDA 3H61A 3TGHA 3H63A 3H64A 3LL8A 1SU1A 1S70A 4FBKA 3GVEA 1IT6A 2WDCA 3H69A 1M63A 3IVDA 4J6OA 2O8AA 2IE4C 2QFPA 4FCXA 2NPPC 5GTUA 1WARA 4FBWA 4M0VA 1KBPA 4TUIA 3C9FA 1TCOA 2WDEA 1Z2WA 2Z72A 2HYPA 1NNWA 1XZWA 3K7WC 1USHA 2DFJA 2QFRA 3QFNA 5IOHA 4DSYA 3RQZA 2AHDA 1T71A 3IB7A 3IVEA 4IYPC 4H2FA 4NZVA 4ORCA 4G9JA 2NYMC 1UTEA 2ZBMA 1Z2XA 3QFOA 2O8GA 3QFMA 3K7VC 3EGHA 2HY1A 4UWQA 1G5BA 3DW8C 4I5NC 1HPUA 3RL3A 4LU9A 4ZX2A 1OIEA 2HYOA 4V0VA 4DT2A 4YKEA 2YVTA 1S3NA 4ZVZA 4KKZA 1OI8A 2BCDA 4JA7A 5JPEA 3HVQA 4F0ZA 2WDFA 4LACC 1II7A 4MP0A 4B2OA 1XM7A 2BDXA 4O5GA 3H68A 5J28A 4MOVA 2Z1AA 4XPNA 1MF8A 2IE3C 5C1VA 3KBPA 3THNA 3THOB 3RL5A 5EQVA 1S3MA 3V4YA 1S95A 1HP1A 3H67A 4JA9A 4DHLA 3E7BA 3ICFA 3QFKA 4I5LC 4V0XA 2KKNA 5F3WA 1S3LA 3H60A 3EGGA 3JYFA 5DNYA 3DSCA 3DSDA 3QG5C 1JK7A 1HO5A 2QJCA 2GJUA 3ZU0A 1OIDA 4H1YP 2XMOA 4IL1A 5B8IA 3AV0A 4UT2A 1QFCA 4FBQA 4OR9A 1U32A 2R17A 4O4KA 3ZTVA 2NXFA 4MOYA 5INBA 4LTYA 3N5UA 4Q7FA 5JPFA 3T1IA 2Z06A 1UF3A 3E7AA 3FGAC 4ORAA 2BQ8X 4H2GA 2A22A 4UT3A 3H62B 4KBPA 4V0WA 4H1SA 3IB8A 3CK2A 5JJTA 3PSOA 4TUGA 4WWLA 1AUIA 4ORBA 2JOGA 4O43A 5HPEA 2USHA 3RL4A 1WAO1 3C5WC 1FJMA 2IAEC
chains in the Genus database with same CATH superfamily
1V73A 4O24A 1S8EA 2Q8UA 2DXNA 2P6BA 1W24A 2NYLC 3P71C 3H66A 1T70A 3AUZA 2DXLA 3PSNA 4H2IA 4H2BA 4HD0A 4UT3B 1QHWA 2CV9A 2WDDA 3D03A 3H61A 3TGHA 3H63A 3H64A 3LL8A 1SU1A 1S70A 4FBKA 3GVEA 1IT6A 2WDCA 3H69A 1M63A 3IVDA 4J6OA 2O8AA 2IE4C 2QFPA 4FCXA 2NPPC 5GTUA 1WARA 4FBWA 4M0VA 1KBPA 4TUIA 3C9FA 1TCOA 2WDEA 1Z2WA 2Z72A 2HYPA 1NNWA 1XZWA 3K7WC 2QFRA 1USHA 2DFJA 2ZOAA 3QFNA 5IOHA 4DSYA 3RQZA 2AHDA 1T71A 3IB7A 3IVEA 4IYPC 4H2FA 4NZVA 4ORCA 4G9JA 2NYMC 1UTEA 2ZBMA 1Z2XA 3QFOA 2O8GA 3QFMA 3K7VC 3EGHA 2HY1A 4UWQA 1G5BA 3DW8C 4I5NC 1HPUA 3RL3A 4LU9A 4ZX2A 1OIEA 2HYOA 4V0VA 4DT2A 4YKEA 1S3NA 2YVTA 4ZVZA 4KKZA 1OI8A 2BCDA 4JA7A 5JPEA 3HVQA 4F0ZA 2WDFA 4LACC 1II7A 4MP0A 4B2OA 1XM7A 2BDXA 4O5GA 3H68A 5J28A 4MOVA 2Z1AA 4XPNA 1MF8A 2IE3C 5C1VA 3KBPA 3THNA 3THOB 3RL5A 5EQVA 1S3MA 3V4YA 1S95A 2YEQA 1HP1A 3H67A 4JA9A 4DHLA 3E7BA 3ICFA 3QFKA 4I5LC 4V0XA 2KKNA 5F3WA 1S3LA 3H60A 3EGGA 3JYFA 5DNYA 3DSCA 3DSDA 3QG5C 1JK7A 1HO5A 2ZO9B 2QJCA 2GJUA 3ZU0A 1OIDA 4H1YP 2XMOA 4IL1A 5B8IA 3AV0A 4UT2A 1QFCA 4FBQA 4OR9A 1U32A 2R17A 4O4KA 3ZTVA 2NXFA 4MOYA 5INBA 4LTYA 3N5UA 4Q7FA 5JPFA 3T1IA 2Z06A 1UF3A 3E7AA 3FGAC 4ORAA 2BQ8X 4H2GA 2A22A 4UT3A 3H62B 4KBPA 4V0WA 4H1SA 3FLOA 3IB8A 3CK2A 5JJTA 3PSOA 4TUGA 4WWLA 1AUIA 4ORBA 2JOGA 4O43A 5HPEA 2USHA 3E0JA 3RL4A 1WAO1 3C5WC 1FJMA 2IAEC
chains in the Genus database with same CATH topology
1V73A 4O24A 1S8EA 2Q8UA 2DXNA 2P6BA 1W24A 2NYLC 3P71C 3H66A 1T70A 3AUZA 2DXLA 3PSNA 4H2IA 4H2BA 4HD0A 4UT3B 1QHWA 2CV9A 2WDDA 3D03A 3H61A 3TGHA 3H63A 3H64A 3LL8A 1SU1A 1S70A 4FBKA 3GVEA 1IT6A 2WDCA 3H69A 1M63A 3IVDA 4J6OA 2O8AA 2IE4C 2QFPA 4FCXA 2NPPC 5GTUA 1WARA 4FBWA 4M0VA 1KBPA 4TUIA 3C9FA 1TCOA 2WDEA 1Z2WA 2Z72A 2HYPA 1NNWA 1XZWA 3K7WC 2QFRA 1USHA 2DFJA 2ZOAA 3QFNA 5IOHA 4DSYA 3RQZA 2AHDA 1T71A 3IB7A 3IVEA 4IYPC 4H2FA 4NZVA 4ORCA 4G9JA 2NYMC 1UTEA 2ZBMA 1Z2XA 3QFOA 2O8GA 3QFMA 3K7VC 3EGHA 2HY1A 4UWQA 1G5BA 3DW8C 4I5NC 1HPUA 3RL3A 4LU9A 4ZX2A 1OIEA 2HYOA 4V0VA 4DT2A 4YKEA 1S3NA 2YVTA 4ZVZA 4KKZA 1OI8A 2BCDA 4JA7A 5JPEA 3HVQA 4F0ZA 2WDFA 4LACC 1II7A 4MP0A 4B2OA 1XM7A 2BDXA 4O5GA 3H68A 5J28A 4MOVA 2Z1AA 4XPNA 1MF8A 2IE3C 5C1VA 3KBPA 3THNA 3THOB 3RL5A 5EQVA 1S3MA 3V4YA 1S95A 2YEQA 1HP1A 3H67A 4JA9A 4DHLA 3E7BA 3ICFA 3QFKA 4I5LC 4V0XA 2KKNA 5F3WA 1S3LA 3H60A 3EGGA 3JYFA 5DNYA 3DSCA 3DSDA 3QG5C 1JK7A 1HO5A 2ZO9B 2QJCA 2GJUA 3ZU0A 1OIDA 4H1YP 2XMOA 4IL1A 5B8IA 3AV0A 4UT2A 1QFCA 4FBQA 4OR9A 1U32A 2R17A 4O4KA 3ZTVA 2NXFA 4MOYA 5INBA 4LTYA 3N5UA 4Q7FA 5JPFA 3T1IA 2Z06A 1UF3A 3E7AA 3FGAC 4ORAA 2BQ8X 4H2GA 2A22A 4UT3A 3H62B 4KBPA 4V0WA 4H1SA 3FLOA 3IB8A 3CK2A 5JJTA 3PSOA 4TUGA 4WWLA 1AUIA 4ORBA 2JOGA 4O43A 5HPEA 2USHA 3E0JA 3RL4A 1WAO1 3C5WC 1FJMA 2IAEC
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1V73 A;  4O24 A;  1S8E A;  2Q8U A;  2P6B A;  1W24 A;  2NYL C;  3P71 C;  3H66 A;  1T70 A;  3AUZ A;  3PSN A;  4H2I A;  4H2B A;  4HD0 A;  4UT3 B;  1QHW A;  2CV9 A;  2WDD A;  3H61 A;  3TGH A;  3H63 A;  3H64 A;  3LL8 A;  1SU1 A;  1S70 A;  4FBK A;  3GVE A;  1IT6 A;  2WDC A;  3H69 A;  1M63 A;  3IVD A;  4J6O A;  2O8A A;  2IE4 C;  2QFP A;  4FCX A;  2NPP C;  5GTU A;  1WAR A;  4FBW A;  4M0V A;  1KBP A;  4TUI A;  3C9F A;  1TCO A;  2WDE A;  1Z2W A;  2Z72 A;  2HYP A;  1NNW A;  1XZW A;  3K7W C;  1USH A;  2DFJ A;  2QFR A;  3QFN A;  5IOH A;  4DSY A;  3RQZ A;  2AHD A;  1T71 A;  3IB7 A;  3IVE A;  4IYP C;  4H2F A;  4NZV A;  4ORC A;  4G9J A;  2NYM C;  1UTE A;  2ZBM A;  1Z2X A;  3QFO A;  2O8G A;  3QFM A;  3K7V C;  3EGH A;  2HY1 A;  4UWQ A;  1G5B A;  3DW8 C;  4I5N C;  1HPU A;  3RL3 A;  4LU9 A;  4ZX2 A;  1OIE A;  2HYO A;  4V0V A;  4DT2 A;  4YKE A;  2YVT A;  1S3N A;  4ZVZ A;  4KKZ A;  1OI8 A;  2BCD A;  4JA7 A;  5JPE A;  3HVQ A;  4F0Z A;  2WDF A;  4LAC C;  1II7 A;  4MP0 A;  4B2O A;  1XM7 A;  2BDX A;  4O5G A;  3H68 A;  5J28 A;  4MOV A;  2Z1A A;  4XPN A;  1MF8 A;  2IE3 C;  5C1V A;  3KBP A;  3THN A;  3THO B;  3RL5 A;  5EQV A;  1S3M A;  3V4Y A;  1S95 A;  1HP1 A;  3H67 A;  4JA9 A;  4DHL A;  3E7B A;  3ICF A;  3QFK A;  4I5L C;  4V0X A;  2KKN A;  5F3W A;  1S3L A;  3H60 A;  3EGG A;  3JYF A;  5DNY A;  3DSC A;  3DSD A;  3QG5 C;  1JK7 A;  1HO5 A;  2QJC A;  2GJU A;  3ZU0 A;  1OID A;  4H1Y P;  2XMO A;  4IL1 A;  5B8I A;  3AV0 A;  4UT2 A;  1QFC A;  4FBQ A;  4OR9 A;  1U32 A;  2R17 A;  4O4K A;  3ZTV A;  2NXF A;  4MOY A;  5INB A;  4LTY A;  3N5U A;  4Q7F A;  5JPF A;  3T1I A;  2Z06 A;  1UF3 A;  3E7A A;  3FGA C;  4ORA A;  2BQ8 X;  4H2G A;  2A22 A;  4UT3 A;  3H62 B;  4KBP A;  4V0W A;  4H1S A;  3IB8 A;  3CK2 A;  5JJT A;  3PSO A;  4TUG A;  4WWL A;  1AUI A;  4ORB A;  2JOG A;  4O43 A;  5HPE A;  2USH A;  3RL4 A;  1WAO 1;  3C5W C;  1FJM A;  2IAE C; 
#chains in the Genus database with same CATH topology
 1V73 A;  4O24 A;  1S8E A;  2Q8U A;  2DXN A;  2P6B A;  1W24 A;  2NYL C;  3P71 C;  3H66 A;  1T70 A;  3AUZ A;  2DXL A;  3PSN A;  4H2I A;  4H2B A;  4HD0 A;  4UT3 B;  1QHW A;  2CV9 A;  2WDD A;  3D03 A;  3H61 A;  3TGH A;  3H63 A;  3H64 A;  3LL8 A;  1SU1 A;  1S70 A;  4FBK A;  3GVE A;  1IT6 A;  2WDC A;  3H69 A;  1M63 A;  3IVD A;  4J6O A;  2O8A A;  2IE4 C;  2QFP A;  4FCX A;  2NPP C;  5GTU A;  1WAR A;  4FBW A;  4M0V A;  1KBP A;  4TUI A;  3C9F A;  1TCO A;  2WDE A;  1Z2W A;  2Z72 A;  2HYP A;  1NNW A;  1XZW A;  3K7W C;  2QFR A;  1USH A;  2DFJ A;  2ZOA A;  3QFN A;  5IOH A;  4DSY A;  3RQZ A;  2AHD A;  1T71 A;  3IB7 A;  3IVE A;  4IYP C;  4H2F A;  4NZV A;  4ORC A;  4G9J A;  2NYM C;  1UTE A;  2ZBM A;  1Z2X A;  3QFO A;  2O8G A;  3QFM A;  3K7V C;  3EGH A;  2HY1 A;  4UWQ A;  1G5B A;  3DW8 C;  4I5N C;  1HPU A;  3RL3 A;  4LU9 A;  4ZX2 A;  1OIE A;  2HYO A;  4V0V A;  4DT2 A;  4YKE A;  1S3N A;  2YVT A;  4ZVZ A;  4KKZ A;  1OI8 A;  2BCD A;  4JA7 A;  5JPE A;  3HVQ A;  4F0Z A;  2WDF A;  4LAC C;  1II7 A;  4MP0 A;  4B2O A;  1XM7 A;  2BDX A;  4O5G A;  3H68 A;  5J28 A;  4MOV A;  2Z1A A;  4XPN A;  1MF8 A;  2IE3 C;  5C1V A;  3KBP A;  3THN A;  3THO B;  3RL5 A;  5EQV A;  1S3M A;  3V4Y A;  1S95 A;  2YEQ A;  1HP1 A;  3H67 A;  4JA9 A;  4DHL A;  3E7B A;  3ICF A;  3QFK A;  4I5L C;  4V0X A;  2KKN A;  5F3W A;  1S3L A;  3H60 A;  3EGG A;  3JYF A;  5DNY A;  3DSC A;  3DSD A;  3QG5 C;  1JK7 A;  1HO5 A;  2ZO9 B;  2QJC A;  2GJU A;  3ZU0 A;  1OID A;  4H1Y P;  2XMO A;  4IL1 A;  5B8I A;  3AV0 A;  4UT2 A;  1QFC A;  4FBQ A;  4OR9 A;  1U32 A;  2R17 A;  4O4K A;  3ZTV A;  2NXF A;  4MOY A;  5INB A;  4LTY A;  3N5U A;  4Q7F A;  5JPF A;  3T1I A;  2Z06 A;  1UF3 A;  3E7A A;  3FGA C;  4ORA A;  2BQ8 X;  4H2G A;  2A22 A;  4UT3 A;  3H62 B;  4KBP A;  4V0W A;  4H1S A;  3FLO A;  3IB8 A;  3CK2 A;  5JJT A;  3PSO A;  4TUG A;  4WWL A;  1AUI A;  4ORB A;  2JOG A;  4O43 A;  5HPE A;  2USH A;  3E0J A;  3RL4 A;  1WAO 1;  3C5W C;  1FJM A;  2IAE C; 
#chains in the Genus database with same CATH homology
 1V73 A;  4O24 A;  1S8E A;  2Q8U A;  2DXN A;  2P6B A;  1W24 A;  2NYL C;  3P71 C;  3H66 A;  1T70 A;  3AUZ A;  2DXL A;  3PSN A;  4H2I A;  4H2B A;  4HD0 A;  4UT3 B;  1QHW A;  2CV9 A;  2WDD A;  3D03 A;  3H61 A;  3TGH A;  3H63 A;  3H64 A;  3LL8 A;  1SU1 A;  1S70 A;  4FBK A;  3GVE A;  1IT6 A;  2WDC A;  3H69 A;  1M63 A;  3IVD A;  4J6O A;  2O8A A;  2IE4 C;  2QFP A;  4FCX A;  2NPP C;  5GTU A;  1WAR A;  4FBW A;  4M0V A;  1KBP A;  4TUI A;  3C9F A;  1TCO A;  2WDE A;  1Z2W A;  2Z72 A;  2HYP A;  1NNW A;  1XZW A;  3K7W C;  2QFR A;  1USH A;  2DFJ A;  2ZOA A;  3QFN A;  5IOH A;  4DSY A;  3RQZ A;  2AHD A;  1T71 A;  3IB7 A;  3IVE A;  4IYP C;  4H2F A;  4NZV A;  4ORC A;  4G9J A;  2NYM C;  1UTE A;  2ZBM A;  1Z2X A;  3QFO A;  2O8G A;  3QFM A;  3K7V C;  3EGH A;  2HY1 A;  4UWQ A;  1G5B A;  3DW8 C;  4I5N C;  1HPU A;  3RL3 A;  4LU9 A;  4ZX2 A;  1OIE A;  2HYO A;  4V0V A;  4DT2 A;  4YKE A;  1S3N A;  2YVT A;  4ZVZ A;  4KKZ A;  1OI8 A;  2BCD A;  4JA7 A;  5JPE A;  3HVQ A;  4F0Z A;  2WDF A;  4LAC C;  1II7 A;  4MP0 A;  4B2O A;  1XM7 A;  2BDX A;  4O5G A;  3H68 A;  5J28 A;  4MOV A;  2Z1A A;  4XPN A;  1MF8 A;  2IE3 C;  5C1V A;  3KBP A;  3THN A;  3THO B;  3RL5 A;  5EQV A;  1S3M A;  3V4Y A;  1S95 A;  2YEQ A;  1HP1 A;  3H67 A;  4JA9 A;  4DHL A;  3E7B A;  3ICF A;  3QFK A;  4I5L C;  4V0X A;  2KKN A;  5F3W A;  1S3L A;  3H60 A;  3EGG A;  3JYF A;  5DNY A;  3DSC A;  3DSD A;  3QG5 C;  1JK7 A;  1HO5 A;  2ZO9 B;  2QJC A;  2GJU A;  3ZU0 A;  1OID A;  4H1Y P;  2XMO A;  4IL1 A;  5B8I A;  3AV0 A;  4UT2 A;  1QFC A;  4FBQ A;  4OR9 A;  1U32 A;  2R17 A;  4O4K A;  3ZTV A;  2NXF A;  4MOY A;  5INB A;  4LTY A;  3N5U A;  4Q7F A;  5JPF A;  3T1I A;  2Z06 A;  1UF3 A;  3E7A A;  3FGA C;  4ORA A;  2BQ8 X;  4H2G A;  2A22 A;  4UT3 A;  3H62 B;  4KBP A;  4V0W A;  4H1S A;  3FLO A;  3IB8 A;  3CK2 A;  5JJT A;  3PSO A;  4TUG A;  4WWL A;  1AUI A;  4ORB A;  2JOG A;  4O43 A;  5HPE A;  2USH A;  3E0J A;  3RL4 A;  1WAO 1;  3C5W C;  1FJM A;  2IAE C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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