3RL3A

Rat metallophosphodiesterase mpped2
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
281
structure length
276
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Metallophosphoesterase MPPED2
total genus 86
structure length 276
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl3A00
4YKEA 5IOHA 3HVQA 4MOVA 2NYMC 4H1SA 1W24A 4NZVA 4O5GA 4V0WA 1UTEA 1XZWA 4FBQA 2AHDA 3IB8A 3LL8A 1OIDA 2QJCA 3AV0A 4ZX2A 1IT6A 4H2IA 2Z06A 4I5NC 4H2GA 2WDCA 3C9FA 1U32A 2O8AA 4ORBA 4IL1A 4V0VA 4TUGA 4LACC 4IYPC 4O43A 5B8IA 4H2BA 4KBPA 4O24A 3EGHA 4M0VA 4UWQA 3TGHA 3DSCA 3ZU0A 2IAEC 3H69A 4LTYA 5C1VA 3QFOA 4XPNA 4UT3B 4Q7FA 3KBPA 1UF3A 2BQ8X 2GJUA 1USHA 2HYOA 4UT2A 1HO5A 1AUIA 1WAO1 2YVTA 3FGAC 5EQVA 1OIEA 5GTUA 3RL3A 3RL5A 2NPPC 1M63A 4H1YP 3E7AA 4DT2A 3DSDA 2HY1A 5J28A 1MF8A 2DFJA 5DNYA 3H61A 4J6OA 3H67A 4V0XA 4F0ZA 2CV9A 4JA9A 3JYFA 4O4KA 1KBPA 2A22A 5INBA 3H60A 1S3MA 2KKNA 3DW8C 1S95A 4ZVZA 4TUIA 3THOB 2QFPA 4I5LC 1TCOA 1WARA 1Z2XA 4UT3A 1JK7A 4G9JA 3K7VC 1G5BA 2R17A 2Q8UA 3IVDA 4H2FA 4ORCA 2BCDA 2HYPA 3QFNA 5F3WA 3P71C 2P6BA 1S70A 3QG5C 2NYLC 3H68A 1V73A 4DSYA 3H66A 4MOYA 3CK2A 5JJTA 3AUZA 3ZTVA 3E7BA 2Z1AA 4JA7A 2Z72A 5JPFA 3K7WC 2BDXA 1Z2WA 4OR9A 1QHWA 2IE3C 4WWLA 2O8GA 3EGGA 4B2OA 1HP1A 1HPUA 4DHLA 3C5WC 1SU1A 2USHA 3QFMA 4FBWA 3H64A 2WDDA 3IB7A 3PSNA 4LU9A 3H62B 4FBKA 3H63A 2WDEA 2XMOA 4HD0A 1XM7A 3RQZA 1QFCA 5JPEA 3IVEA 1S8EA 4KKZA 1T71A 1S3NA 1OI8A 2ZBMA 2QFRA 3RL4A 1II7A 3PSOA 5HPEA 1T70A 2NXFA 3V4YA 2IE4C 3N5UA 3T1IA 2JOGA 2WDFA 1NNWA 3ICFA 4ORAA 3THNA 1S3LA 1FJMA 3GVEA 4FCXA 4MP0A 3QFKA
chains in the Genus database with same CATH superfamily
4YKEA 5IOHA 3HVQA 2DXNA 4MOVA 2NYMC 4H1SA 1W24A 4NZVA 4O5GA 4V0WA 1UTEA 1XZWA 4FBQA 2AHDA 3IB8A 3LL8A 1OIDA 2QJCA 3AV0A 4ZX2A 1IT6A 4H2IA 2Z06A 4I5NC 4H2GA 2WDCA 3C9FA 1U32A 2O8AA 4ORBA 4IL1A 4V0VA 4TUGA 4LACC 4IYPC 4O43A 5B8IA 4H2BA 4KBPA 4O24A 3EGHA 4M0VA 4UWQA 2ZOAA 3TGHA 3DSCA 3ZU0A 2IAEC 3H69A 4LTYA 5C1VA 3QFOA 4XPNA 4UT3B 4Q7FA 3D03A 3KBPA 1UF3A 2BQ8X 2DXLA 2GJUA 1USHA 2HYOA 4UT2A 1HO5A 1AUIA 1WAO1 2YVTA 3FGAC 5EQVA 1OIEA 5GTUA 3RL3A 3RL5A 2NPPC 1M63A 4H1YP 3E7AA 4DT2A 3DSDA 2HY1A 5J28A 1MF8A 2DFJA 5DNYA 3H61A 4J6OA 3H67A 4V0XA 4F0ZA 2CV9A 4JA9A 3JYFA 4O4KA 1KBPA 2A22A 5INBA 3H60A 1S3MA 2KKNA 3DW8C 1S95A 4ZVZA 4TUIA 3THOB 2QFPA 4I5LC 1TCOA 1WARA 1Z2XA 4UT3A 1JK7A 4G9JA 3K7VC 1G5BA 2R17A 2Q8UA 3IVDA 4H2FA 4ORCA 2BCDA 2HYPA 3QFNA 5F3WA 3P71C 2P6BA 1S70A 3QG5C 2NYLC 3H68A 1V73A 4DSYA 3H66A 4MOYA 3CK2A 5JJTA 3AUZA 3ZTVA 3E7BA 2Z1AA 4JA7A 2Z72A 5JPFA 3K7WC 2BDXA 1Z2WA 4OR9A 1QHWA 2IE3C 4WWLA 2O8GA 3EGGA 4B2OA 1HP1A 1HPUA 3FLOA 4DHLA 3C5WC 1SU1A 2USHA 3QFMA 4FBWA 3H64A 2WDDA 3IB7A 3PSNA 4LU9A 3H62B 4FBKA 3H63A 2YEQA 2WDEA 2XMOA 4HD0A 1XM7A 3RQZA 1QFCA 5JPEA 3IVEA 1S8EA 4KKZA 1T71A 3E0JA 1S3NA 1OI8A 2ZBMA 2QFRA 3RL4A 1II7A 3PSOA 5HPEA 1T70A 2NXFA 3V4YA 2IE4C 3N5UA 3T1IA 2JOGA 2WDFA 1NNWA 3ICFA 4ORAA 3THNA 1S3LA 1FJMA 3GVEA 4FCXA 2ZO9B 4MP0A 3QFKA
chains in the Genus database with same CATH topology
4YKEA 5IOHA 3HVQA 2DXNA 4MOVA 2NYMC 4H1SA 1W24A 4NZVA 4O5GA 4V0WA 1UTEA 1XZWA 4FBQA 2AHDA 3IB8A 3LL8A 1OIDA 2QJCA 3AV0A 4ZX2A 1IT6A 4H2IA 2Z06A 4I5NC 4H2GA 2WDCA 3C9FA 1U32A 2O8AA 4ORBA 4IL1A 4V0VA 4TUGA 4LACC 4IYPC 4O43A 5B8IA 4H2BA 4KBPA 4O24A 3EGHA 4M0VA 4UWQA 2ZOAA 3TGHA 3DSCA 3ZU0A 2IAEC 3H69A 4LTYA 5C1VA 3QFOA 4XPNA 4UT3B 4Q7FA 3D03A 3KBPA 1UF3A 2BQ8X 2DXLA 2GJUA 1USHA 2HYOA 4UT2A 1HO5A 1AUIA 1WAO1 2YVTA 3FGAC 5EQVA 1OIEA 5GTUA 3RL3A 3RL5A 2NPPC 1M63A 4H1YP 3E7AA 4DT2A 3DSDA 2HY1A 5J28A 1MF8A 2DFJA 5DNYA 3H61A 4J6OA 3H67A 4V0XA 4F0ZA 2CV9A 4JA9A 3JYFA 4O4KA 1KBPA 2A22A 5INBA 3H60A 1S3MA 2KKNA 3DW8C 1S95A 4ZVZA 4TUIA 3THOB 2QFPA 4I5LC 1TCOA 1WARA 1Z2XA 4UT3A 1JK7A 4G9JA 3K7VC 1G5BA 2R17A 2Q8UA 3IVDA 4H2FA 4ORCA 2BCDA 2HYPA 3QFNA 5F3WA 3P71C 2P6BA 1S70A 3QG5C 2NYLC 3H68A 1V73A 4DSYA 3H66A 4MOYA 3CK2A 5JJTA 3AUZA 3ZTVA 3E7BA 2Z1AA 4JA7A 2Z72A 5JPFA 3K7WC 2BDXA 1Z2WA 4OR9A 1QHWA 2IE3C 4WWLA 2O8GA 3EGGA 4B2OA 1HP1A 1HPUA 3FLOA 4DHLA 3C5WC 1SU1A 2USHA 3QFMA 4FBWA 3H64A 2WDDA 3IB7A 3PSNA 4LU9A 3H62B 4FBKA 3H63A 2YEQA 2WDEA 2XMOA 4HD0A 1XM7A 3RQZA 1QFCA 5JPEA 3IVEA 1S8EA 4KKZA 1T71A 3E0JA 1S3NA 1OI8A 2ZBMA 2QFRA 3RL4A 1II7A 3PSOA 5HPEA 1T70A 2NXFA 3V4YA 2IE4C 3N5UA 3T1IA 2JOGA 2WDFA 1NNWA 3ICFA 4ORAA 3THNA 1S3LA 1FJMA 3GVEA 4FCXA 2ZO9B 4MP0A 3QFKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YKE A;  5IOH A;  3HVQ A;  4MOV A;  2NYM C;  4H1S A;  1W24 A;  4NZV A;  4O5G A;  4V0W A;  1UTE A;  1XZW A;  4FBQ A;  2AHD A;  3IB8 A;  3LL8 A;  1OID A;  2QJC A;  3AV0 A;  4ZX2 A;  1IT6 A;  4H2I A;  2Z06 A;  4I5N C;  4H2G A;  2WDC A;  3C9F A;  1U32 A;  2O8A A;  4ORB A;  4IL1 A;  4V0V A;  4TUG A;  4LAC C;  4IYP C;  4O43 A;  5B8I A;  4H2B A;  4KBP A;  4O24 A;  3EGH A;  4M0V A;  4UWQ A;  3TGH A;  3DSC A;  3ZU0 A;  2IAE C;  3H69 A;  4LTY A;  5C1V A;  3QFO A;  4XPN A;  4UT3 B;  4Q7F A;  3KBP A;  1UF3 A;  2BQ8 X;  2GJU A;  1USH A;  2HYO A;  4UT2 A;  1HO5 A;  1AUI A;  1WAO 1;  2YVT A;  3FGA C;  5EQV A;  1OIE A;  5GTU A;  3RL3 A;  3RL5 A;  2NPP C;  1M63 A;  4H1Y P;  3E7A A;  4DT2 A;  3DSD A;  2HY1 A;  5J28 A;  1MF8 A;  2DFJ A;  5DNY A;  3H61 A;  4J6O A;  3H67 A;  4V0X A;  4F0Z A;  2CV9 A;  4JA9 A;  3JYF A;  4O4K A;  1KBP A;  2A22 A;  5INB A;  3H60 A;  1S3M A;  2KKN A;  3DW8 C;  1S95 A;  4ZVZ A;  4TUI A;  3THO B;  2QFP A;  4I5L C;  1TCO A;  1WAR A;  1Z2X A;  4UT3 A;  1JK7 A;  4G9J A;  3K7V C;  1G5B A;  2R17 A;  2Q8U A;  3IVD A;  4H2F A;  4ORC A;  2BCD A;  2HYP A;  3QFN A;  5F3W A;  3P71 C;  2P6B A;  1S70 A;  3QG5 C;  2NYL C;  3H68 A;  1V73 A;  4DSY A;  3H66 A;  4MOY A;  3CK2 A;  5JJT A;  3AUZ A;  3ZTV A;  3E7B A;  2Z1A A;  4JA7 A;  2Z72 A;  5JPF A;  3K7W C;  2BDX A;  1Z2W A;  4OR9 A;  1QHW A;  2IE3 C;  4WWL A;  2O8G A;  3EGG A;  4B2O A;  1HP1 A;  1HPU A;  4DHL A;  3C5W C;  1SU1 A;  2USH A;  3QFM A;  4FBW A;  3H64 A;  2WDD A;  3IB7 A;  3PSN A;  4LU9 A;  3H62 B;  4FBK A;  3H63 A;  2WDE A;  2XMO A;  4HD0 A;  1XM7 A;  3RQZ A;  1QFC A;  5JPE A;  3IVE A;  1S8E A;  4KKZ A;  1T71 A;  1S3N A;  1OI8 A;  2ZBM A;  2QFR A;  3RL4 A;  1II7 A;  3PSO A;  5HPE A;  1T70 A;  2NXF A;  3V4Y A;  2IE4 C;  3N5U A;  3T1I A;  2JOG A;  2WDF A;  1NNW A;  3ICF A;  4ORA A;  3THN A;  1S3L A;  1FJM A;  3GVE A;  4FCX A;  4MP0 A;  3QFK A; 
#chains in the Genus database with same CATH topology
 4YKE A;  5IOH A;  3HVQ A;  2DXN A;  4MOV A;  2NYM C;  4H1S A;  1W24 A;  4NZV A;  4O5G A;  4V0W A;  1UTE A;  1XZW A;  4FBQ A;  2AHD A;  3IB8 A;  3LL8 A;  1OID A;  2QJC A;  3AV0 A;  4ZX2 A;  1IT6 A;  4H2I A;  2Z06 A;  4I5N C;  4H2G A;  2WDC A;  3C9F A;  1U32 A;  2O8A A;  4ORB A;  4IL1 A;  4V0V A;  4TUG A;  4LAC C;  4IYP C;  4O43 A;  5B8I A;  4H2B A;  4KBP A;  4O24 A;  3EGH A;  4M0V A;  4UWQ A;  2ZOA A;  3TGH A;  3DSC A;  3ZU0 A;  2IAE C;  3H69 A;  4LTY A;  5C1V A;  3QFO A;  4XPN A;  4UT3 B;  4Q7F A;  3D03 A;  3KBP A;  1UF3 A;  2BQ8 X;  2DXL A;  2GJU A;  1USH A;  2HYO A;  4UT2 A;  1HO5 A;  1AUI A;  1WAO 1;  2YVT A;  3FGA C;  5EQV A;  1OIE A;  5GTU A;  3RL3 A;  3RL5 A;  2NPP C;  1M63 A;  4H1Y P;  3E7A A;  4DT2 A;  3DSD A;  2HY1 A;  5J28 A;  1MF8 A;  2DFJ A;  5DNY A;  3H61 A;  4J6O A;  3H67 A;  4V0X A;  4F0Z A;  2CV9 A;  4JA9 A;  3JYF A;  4O4K A;  1KBP A;  2A22 A;  5INB A;  3H60 A;  1S3M A;  2KKN A;  3DW8 C;  1S95 A;  4ZVZ A;  4TUI A;  3THO B;  2QFP A;  4I5L C;  1TCO A;  1WAR A;  1Z2X A;  4UT3 A;  1JK7 A;  4G9J A;  3K7V C;  1G5B A;  2R17 A;  2Q8U A;  3IVD A;  4H2F A;  4ORC A;  2BCD A;  2HYP A;  3QFN A;  5F3W A;  3P71 C;  2P6B A;  1S70 A;  3QG5 C;  2NYL C;  3H68 A;  1V73 A;  4DSY A;  3H66 A;  4MOY A;  3CK2 A;  5JJT A;  3AUZ A;  3ZTV A;  3E7B A;  2Z1A A;  4JA7 A;  2Z72 A;  5JPF A;  3K7W C;  2BDX A;  1Z2W A;  4OR9 A;  1QHW A;  2IE3 C;  4WWL A;  2O8G A;  3EGG A;  4B2O A;  1HP1 A;  1HPU A;  3FLO A;  4DHL A;  3C5W C;  1SU1 A;  2USH A;  3QFM A;  4FBW A;  3H64 A;  2WDD A;  3IB7 A;  3PSN A;  4LU9 A;  3H62 B;  4FBK A;  3H63 A;  2YEQ A;  2WDE A;  2XMO A;  4HD0 A;  1XM7 A;  3RQZ A;  1QFC A;  5JPE A;  3IVE A;  1S8E A;  4KKZ A;  1T71 A;  3E0J A;  1S3N A;  1OI8 A;  2ZBM A;  2QFR A;  3RL4 A;  1II7 A;  3PSO A;  5HPE A;  1T70 A;  2NXF A;  3V4Y A;  2IE4 C;  3N5U A;  3T1I A;  2JOG A;  2WDF A;  1NNW A;  3ICF A;  4ORA A;  3THN A;  1S3L A;  1FJM A;  3GVE A;  4FCX A;  2ZO9 B;  4MP0 A;  3QFK A; 
#chains in the Genus database with same CATH homology
 4YKE A;  5IOH A;  3HVQ A;  2DXN A;  4MOV A;  2NYM C;  4H1S A;  1W24 A;  4NZV A;  4O5G A;  4V0W A;  1UTE A;  1XZW A;  4FBQ A;  2AHD A;  3IB8 A;  3LL8 A;  1OID A;  2QJC A;  3AV0 A;  4ZX2 A;  1IT6 A;  4H2I A;  2Z06 A;  4I5N C;  4H2G A;  2WDC A;  3C9F A;  1U32 A;  2O8A A;  4ORB A;  4IL1 A;  4V0V A;  4TUG A;  4LAC C;  4IYP C;  4O43 A;  5B8I A;  4H2B A;  4KBP A;  4O24 A;  3EGH A;  4M0V A;  4UWQ A;  2ZOA A;  3TGH A;  3DSC A;  3ZU0 A;  2IAE C;  3H69 A;  4LTY A;  5C1V A;  3QFO A;  4XPN A;  4UT3 B;  4Q7F A;  3D03 A;  3KBP A;  1UF3 A;  2BQ8 X;  2DXL A;  2GJU A;  1USH A;  2HYO A;  4UT2 A;  1HO5 A;  1AUI A;  1WAO 1;  2YVT A;  3FGA C;  5EQV A;  1OIE A;  5GTU A;  3RL3 A;  3RL5 A;  2NPP C;  1M63 A;  4H1Y P;  3E7A A;  4DT2 A;  3DSD A;  2HY1 A;  5J28 A;  1MF8 A;  2DFJ A;  5DNY A;  3H61 A;  4J6O A;  3H67 A;  4V0X A;  4F0Z A;  2CV9 A;  4JA9 A;  3JYF A;  4O4K A;  1KBP A;  2A22 A;  5INB A;  3H60 A;  1S3M A;  2KKN A;  3DW8 C;  1S95 A;  4ZVZ A;  4TUI A;  3THO B;  2QFP A;  4I5L C;  1TCO A;  1WAR A;  1Z2X A;  4UT3 A;  1JK7 A;  4G9J A;  3K7V C;  1G5B A;  2R17 A;  2Q8U A;  3IVD A;  4H2F A;  4ORC A;  2BCD A;  2HYP A;  3QFN A;  5F3W A;  3P71 C;  2P6B A;  1S70 A;  3QG5 C;  2NYL C;  3H68 A;  1V73 A;  4DSY A;  3H66 A;  4MOY A;  3CK2 A;  5JJT A;  3AUZ A;  3ZTV A;  3E7B A;  2Z1A A;  4JA7 A;  2Z72 A;  5JPF A;  3K7W C;  2BDX A;  1Z2W A;  4OR9 A;  1QHW A;  2IE3 C;  4WWL A;  2O8G A;  3EGG A;  4B2O A;  1HP1 A;  1HPU A;  3FLO A;  4DHL A;  3C5W C;  1SU1 A;  2USH A;  3QFM A;  4FBW A;  3H64 A;  2WDD A;  3IB7 A;  3PSN A;  4LU9 A;  3H62 B;  4FBK A;  3H63 A;  2YEQ A;  2WDE A;  2XMO A;  4HD0 A;  1XM7 A;  3RQZ A;  1QFC A;  5JPE A;  3IVE A;  1S8E A;  4KKZ A;  1T71 A;  3E0J A;  1S3N A;  1OI8 A;  2ZBM A;  2QFR A;  3RL4 A;  1II7 A;  3PSO A;  5HPE A;  1T70 A;  2NXF A;  3V4Y A;  2IE4 C;  3N5U A;  3T1I A;  2JOG A;  2WDF A;  1NNW A;  3ICF A;  4ORA A;  3THN A;  1S3L A;  1FJM A;  3GVE A;  4FCX A;  2ZO9 B;  4MP0 A;  3QFK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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