3RL4A

Rat metallophosphodiesterase mpped2 g252h mutant
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
281
structure length
275
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGHIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Metallophosphoesterase MPPED2
total genus 91
structure length 275
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl4A00
5EQVA 2WDFA 2WDCA 3KBPA 2BCDA 3K7VC 4H1SA 3RL3A 1WARA 3P71C 4H1YP 4I5NC 4UT2A 3T1IA 3HVQA 3DSDA 3JYFA 3GVEA 1QHWA 2QFRA 2IE4C 4H2IA 3H61A 2Q8UA 5J28A 3V4YA 2KKNA 2YVTA 3H60A 1T71A 2HYOA 3QFOA 1HO5A 4ORCA 1USHA 2IAEC 2QJCA 2IE3C 4NZVA 3IVEA 3N5UA 1U32A 3IB8A 1G5BA 4O24A 4I5LC 4B2OA 4Q7FA 1FJMA 1M63A 2Z1AA 4H2FA 2WDEA 5DNYA 4OR9A 4IYPC 3C9FA 3QG5C 4FCXA 2DFJA 3FGAC 1S70A 3ICFA 4UT3B 2ZBMA 4FBWA 1TCOA 1S3NA 2XMOA 4G9JA 1UF3A 4H2GA 4ORAA 3RL5A 2JOGA 4J6OA 3H67A 5HPEA 1S8EA 3QFNA 4O43A 1NNWA 1S95A 5IOHA 4FBQA 3IVDA 3H64A 3PSNA 2NXFA 2GJUA 2WDDA 1S3MA 4O4KA 1KBPA 3THNA 4UT3A 2CV9A 2USHA 1QFCA 3PSOA 1OI8A 3QFMA 4KKZA 5B8IA 3AV0A 3RQZA 3THOB 4WWLA 4TUGA 3ZU0A 4MOYA 1MF8A 2A22A 3H63A 4ZX2A 2O8AA 1W24A 2O8GA 4O5GA 1II7A 3DW8C 4KBPA 4YKEA 3ZTVA 4DT2A 4DHLA 3E7BA 3EGGA 3IB7A 3TGHA 5JPFA 3H69A 1AUIA 1OIEA 1XM7A 2NPPC 4LACC 4V0WA 3H68A 4JA9A 5F3WA 3K7WC 4IL1A 1V73A 3RL4A 3CK2A 5INBA 4UWQA 2BQ8X 4V0VA 3H62B 4MOVA 4XPNA 1XZWA 3LL8A 3QFKA 1OIDA 1T70A 4LU9A 1SU1A 4HD0A 4M0VA 4ORBA 4F0ZA 3E7AA 4FBKA 3H66A 1JK7A 2NYMC 5GTUA 4ZVZA 2R17A 5JPEA 2Z06A 4MP0A 1WAO1 1HP1A 1S3LA 2HYPA 2P6BA 5C1VA 1HPUA 2HY1A 1IT6A 4H2BA 4LTYA 5JJTA 3AUZA 2AHDA 3C5WC 4JA7A 2Z72A 3EGHA 1Z2WA 1Z2XA 4V0XA 2QFPA 4DSYA 1UTEA 4TUIA 2BDXA 3DSCA 2NYLC
chains in the Genus database with same CATH superfamily
5EQVA 2WDFA 2WDCA 3KBPA 2BCDA 3K7VC 4H1SA 3RL3A 1WARA 3P71C 4H1YP 4I5NC 4UT2A 3T1IA 3HVQA 3DSDA 3JYFA 3GVEA 1QHWA 2QFRA 3D03A 2IE4C 4H2IA 3H61A 2Q8UA 5J28A 3V4YA 2KKNA 2YVTA 3H60A 1T71A 2HYOA 3QFOA 1HO5A 4ORCA 1USHA 2IAEC 2QJCA 2IE3C 4NZVA 3IVEA 3N5UA 1U32A 3IB8A 1G5BA 4O24A 4I5LC 2ZO9B 4B2OA 4Q7FA 1FJMA 1M63A 2Z1AA 4H2FA 2WDEA 5DNYA 3E0JA 4OR9A 4IYPC 3C9FA 3QG5C 4FCXA 2DFJA 3FGAC 3FLOA 1S70A 3ICFA 4UT3B 2ZBMA 4FBWA 1TCOA 1S3NA 2XMOA 4G9JA 1UF3A 4H2GA 4ORAA 3RL5A 2JOGA 4J6OA 3H67A 5HPEA 1S8EA 3QFNA 4O43A 1NNWA 1S95A 5IOHA 4FBQA 3IVDA 3H64A 3PSNA 2NXFA 2GJUA 2WDDA 1S3MA 4O4KA 1KBPA 3THNA 4UT3A 2CV9A 2USHA 1QFCA 3PSOA 1OI8A 3QFMA 4KKZA 2ZOAA 5B8IA 3AV0A 3RQZA 3THOB 4WWLA 4TUGA 3ZU0A 4MOYA 1MF8A 2A22A 3H63A 4ZX2A 2DXNA 2O8AA 1W24A 2O8GA 4O5GA 1II7A 3DW8C 4KBPA 4YKEA 3ZTVA 4DT2A 4DHLA 2DXLA 3E7BA 3EGGA 3IB7A 3TGHA 5JPFA 3H69A 1AUIA 1OIEA 1XM7A 2NPPC 4LACC 4V0WA 3H68A 4JA9A 5F3WA 3K7WC 4IL1A 1V73A 3RL4A 3CK2A 5INBA 4UWQA 2BQ8X 4V0VA 3H62B 4MOVA 4XPNA 1XZWA 3LL8A 3QFKA 1OIDA 1T70A 4LU9A 1SU1A 4HD0A 4M0VA 4ORBA 4F0ZA 3E7AA 4FBKA 3H66A 1JK7A 2NYMC 5GTUA 4ZVZA 2R17A 5JPEA 2Z06A 4MP0A 1WAO1 1HP1A 1S3LA 2HYPA 2P6BA 5C1VA 1HPUA 2YEQA 2HY1A 1IT6A 4H2BA 4LTYA 5JJTA 3AUZA 2AHDA 3C5WC 4JA7A 2Z72A 3EGHA 1Z2WA 1Z2XA 4V0XA 2QFPA 4DSYA 1UTEA 4TUIA 2BDXA 3DSCA 2NYLC
chains in the Genus database with same CATH topology
5EQVA 2WDFA 2WDCA 3KBPA 2BCDA 3K7VC 4H1SA 3RL3A 1WARA 3P71C 4H1YP 4I5NC 4UT2A 3T1IA 3HVQA 3DSDA 3JYFA 3GVEA 1QHWA 2QFRA 3D03A 2IE4C 4H2IA 3H61A 2Q8UA 5J28A 3V4YA 2KKNA 2YVTA 3H60A 1T71A 2HYOA 3QFOA 1HO5A 4ORCA 1USHA 2IAEC 2QJCA 2IE3C 4NZVA 3IVEA 3N5UA 1U32A 3IB8A 1G5BA 4O24A 4I5LC 2ZO9B 4B2OA 4Q7FA 1FJMA 1M63A 2Z1AA 4H2FA 2WDEA 5DNYA 3E0JA 4OR9A 4IYPC 3C9FA 3QG5C 4FCXA 2DFJA 3FGAC 3FLOA 1S70A 3ICFA 4UT3B 2ZBMA 4FBWA 1TCOA 1S3NA 2XMOA 4G9JA 1UF3A 4H2GA 4ORAA 3RL5A 2JOGA 4J6OA 3H67A 5HPEA 1S8EA 3QFNA 4O43A 1NNWA 1S95A 5IOHA 4FBQA 3IVDA 3H64A 3PSNA 2NXFA 2GJUA 2WDDA 1S3MA 4O4KA 1KBPA 3THNA 4UT3A 2CV9A 2USHA 1QFCA 3PSOA 1OI8A 3QFMA 4KKZA 2ZOAA 5B8IA 3AV0A 3RQZA 3THOB 4WWLA 4TUGA 3ZU0A 4MOYA 1MF8A 2A22A 3H63A 4ZX2A 2DXNA 2O8AA 1W24A 2O8GA 4O5GA 1II7A 3DW8C 4KBPA 4YKEA 3ZTVA 4DT2A 4DHLA 2DXLA 3E7BA 3EGGA 3IB7A 3TGHA 5JPFA 3H69A 1AUIA 1OIEA 1XM7A 2NPPC 4LACC 4V0WA 3H68A 4JA9A 5F3WA 3K7WC 4IL1A 1V73A 3RL4A 3CK2A 5INBA 4UWQA 2BQ8X 4V0VA 3H62B 4MOVA 4XPNA 1XZWA 3LL8A 3QFKA 1OIDA 1T70A 4LU9A 1SU1A 4HD0A 4M0VA 4ORBA 4F0ZA 3E7AA 4FBKA 3H66A 1JK7A 2NYMC 5GTUA 4ZVZA 2R17A 5JPEA 2Z06A 4MP0A 1WAO1 1HP1A 1S3LA 2HYPA 2P6BA 5C1VA 1HPUA 2YEQA 2HY1A 1IT6A 4H2BA 4LTYA 5JJTA 3AUZA 2AHDA 3C5WC 4JA7A 2Z72A 3EGHA 1Z2WA 1Z2XA 4V0XA 2QFPA 4DSYA 1UTEA 4TUIA 2BDXA 3DSCA 2NYLC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EQV A;  2WDF A;  2WDC A;  3KBP A;  2BCD A;  3K7V C;  4H1S A;  3RL3 A;  1WAR A;  3P71 C;  4H1Y P;  4I5N C;  4UT2 A;  3T1I A;  3HVQ A;  3DSD A;  3JYF A;  3GVE A;  1QHW A;  2QFR A;  2IE4 C;  4H2I A;  3H61 A;  2Q8U A;  5J28 A;  3V4Y A;  2KKN A;  2YVT A;  3H60 A;  1T71 A;  2HYO A;  3QFO A;  1HO5 A;  4ORC A;  1USH A;  2IAE C;  2QJC A;  2IE3 C;  4NZV A;  3IVE A;  3N5U A;  1U32 A;  3IB8 A;  1G5B A;  4O24 A;  4I5L C;  4B2O A;  4Q7F A;  1FJM A;  1M63 A;  2Z1A A;  4H2F A;  2WDE A;  5DNY A;  4OR9 A;  4IYP C;  3C9F A;  3QG5 C;  4FCX A;  2DFJ A;  3FGA C;  1S70 A;  3ICF A;  4UT3 B;  2ZBM A;  4FBW A;  1TCO A;  1S3N A;  2XMO A;  4G9J A;  1UF3 A;  4H2G A;  4ORA A;  3RL5 A;  2JOG A;  4J6O A;  3H67 A;  5HPE A;  1S8E A;  3QFN A;  4O43 A;  1NNW A;  1S95 A;  5IOH A;  4FBQ A;  3IVD A;  3H64 A;  3PSN A;  2NXF A;  2GJU A;  2WDD A;  1S3M A;  4O4K A;  1KBP A;  3THN A;  4UT3 A;  2CV9 A;  2USH A;  1QFC A;  3PSO A;  1OI8 A;  3QFM A;  4KKZ A;  5B8I A;  3AV0 A;  3RQZ A;  3THO B;  4WWL A;  4TUG A;  3ZU0 A;  4MOY A;  1MF8 A;  2A22 A;  3H63 A;  4ZX2 A;  2O8A A;  1W24 A;  2O8G A;  4O5G A;  1II7 A;  3DW8 C;  4KBP A;  4YKE A;  3ZTV A;  4DT2 A;  4DHL A;  3E7B A;  3EGG A;  3IB7 A;  3TGH A;  5JPF A;  3H69 A;  1AUI A;  1OIE A;  1XM7 A;  2NPP C;  4LAC C;  4V0W A;  3H68 A;  4JA9 A;  5F3W A;  3K7W C;  4IL1 A;  1V73 A;  3RL4 A;  3CK2 A;  5INB A;  4UWQ A;  2BQ8 X;  4V0V A;  3H62 B;  4MOV A;  4XPN A;  1XZW A;  3LL8 A;  3QFK A;  1OID A;  1T70 A;  4LU9 A;  1SU1 A;  4HD0 A;  4M0V A;  4ORB A;  4F0Z A;  3E7A A;  4FBK A;  3H66 A;  1JK7 A;  2NYM C;  5GTU A;  4ZVZ A;  2R17 A;  5JPE A;  2Z06 A;  4MP0 A;  1WAO 1;  1HP1 A;  1S3L A;  2HYP A;  2P6B A;  5C1V A;  1HPU A;  2HY1 A;  1IT6 A;  4H2B A;  4LTY A;  5JJT A;  3AUZ A;  2AHD A;  3C5W C;  4JA7 A;  2Z72 A;  3EGH A;  1Z2W A;  1Z2X A;  4V0X A;  2QFP A;  4DSY A;  1UTE A;  4TUI A;  2BDX A;  3DSC A;  2NYL C; 
#chains in the Genus database with same CATH topology
 5EQV A;  2WDF A;  2WDC A;  3KBP A;  2BCD A;  3K7V C;  4H1S A;  3RL3 A;  1WAR A;  3P71 C;  4H1Y P;  4I5N C;  4UT2 A;  3T1I A;  3HVQ A;  3DSD A;  3JYF A;  3GVE A;  1QHW A;  2QFR A;  3D03 A;  2IE4 C;  4H2I A;  3H61 A;  2Q8U A;  5J28 A;  3V4Y A;  2KKN A;  2YVT A;  3H60 A;  1T71 A;  2HYO A;  3QFO A;  1HO5 A;  4ORC A;  1USH A;  2IAE C;  2QJC A;  2IE3 C;  4NZV A;  3IVE A;  3N5U A;  1U32 A;  3IB8 A;  1G5B A;  4O24 A;  4I5L C;  2ZO9 B;  4B2O A;  4Q7F A;  1FJM A;  1M63 A;  2Z1A A;  4H2F A;  2WDE A;  5DNY A;  3E0J A;  4OR9 A;  4IYP C;  3C9F A;  3QG5 C;  4FCX A;  2DFJ A;  3FGA C;  3FLO A;  1S70 A;  3ICF A;  4UT3 B;  2ZBM A;  4FBW A;  1TCO A;  1S3N A;  2XMO A;  4G9J A;  1UF3 A;  4H2G A;  4ORA A;  3RL5 A;  2JOG A;  4J6O A;  3H67 A;  5HPE A;  1S8E A;  3QFN A;  4O43 A;  1NNW A;  1S95 A;  5IOH A;  4FBQ A;  3IVD A;  3H64 A;  3PSN A;  2NXF A;  2GJU A;  2WDD A;  1S3M A;  4O4K A;  1KBP A;  3THN A;  4UT3 A;  2CV9 A;  2USH A;  1QFC A;  3PSO A;  1OI8 A;  3QFM A;  4KKZ A;  2ZOA A;  5B8I A;  3AV0 A;  3RQZ A;  3THO B;  4WWL A;  4TUG A;  3ZU0 A;  4MOY A;  1MF8 A;  2A22 A;  3H63 A;  4ZX2 A;  2DXN A;  2O8A A;  1W24 A;  2O8G A;  4O5G A;  1II7 A;  3DW8 C;  4KBP A;  4YKE A;  3ZTV A;  4DT2 A;  4DHL A;  2DXL A;  3E7B A;  3EGG A;  3IB7 A;  3TGH A;  5JPF A;  3H69 A;  1AUI A;  1OIE A;  1XM7 A;  2NPP C;  4LAC C;  4V0W A;  3H68 A;  4JA9 A;  5F3W A;  3K7W C;  4IL1 A;  1V73 A;  3RL4 A;  3CK2 A;  5INB A;  4UWQ A;  2BQ8 X;  4V0V A;  3H62 B;  4MOV A;  4XPN A;  1XZW A;  3LL8 A;  3QFK A;  1OID A;  1T70 A;  4LU9 A;  1SU1 A;  4HD0 A;  4M0V A;  4ORB A;  4F0Z A;  3E7A A;  4FBK A;  3H66 A;  1JK7 A;  2NYM C;  5GTU A;  4ZVZ A;  2R17 A;  5JPE A;  2Z06 A;  4MP0 A;  1WAO 1;  1HP1 A;  1S3L A;  2HYP A;  2P6B A;  5C1V A;  1HPU A;  2YEQ A;  2HY1 A;  1IT6 A;  4H2B A;  4LTY A;  5JJT A;  3AUZ A;  2AHD A;  3C5W C;  4JA7 A;  2Z72 A;  3EGH A;  1Z2W A;  1Z2X A;  4V0X A;  2QFP A;  4DSY A;  1UTE A;  4TUI A;  2BDX A;  3DSC A;  2NYL C; 
#chains in the Genus database with same CATH homology
 5EQV A;  2WDF A;  2WDC A;  3KBP A;  2BCD A;  3K7V C;  4H1S A;  3RL3 A;  1WAR A;  3P71 C;  4H1Y P;  4I5N C;  4UT2 A;  3T1I A;  3HVQ A;  3DSD A;  3JYF A;  3GVE A;  1QHW A;  2QFR A;  3D03 A;  2IE4 C;  4H2I A;  3H61 A;  2Q8U A;  5J28 A;  3V4Y A;  2KKN A;  2YVT A;  3H60 A;  1T71 A;  2HYO A;  3QFO A;  1HO5 A;  4ORC A;  1USH A;  2IAE C;  2QJC A;  2IE3 C;  4NZV A;  3IVE A;  3N5U A;  1U32 A;  3IB8 A;  1G5B A;  4O24 A;  4I5L C;  2ZO9 B;  4B2O A;  4Q7F A;  1FJM A;  1M63 A;  2Z1A A;  4H2F A;  2WDE A;  5DNY A;  3E0J A;  4OR9 A;  4IYP C;  3C9F A;  3QG5 C;  4FCX A;  2DFJ A;  3FGA C;  3FLO A;  1S70 A;  3ICF A;  4UT3 B;  2ZBM A;  4FBW A;  1TCO A;  1S3N A;  2XMO A;  4G9J A;  1UF3 A;  4H2G A;  4ORA A;  3RL5 A;  2JOG A;  4J6O A;  3H67 A;  5HPE A;  1S8E A;  3QFN A;  4O43 A;  1NNW A;  1S95 A;  5IOH A;  4FBQ A;  3IVD A;  3H64 A;  3PSN A;  2NXF A;  2GJU A;  2WDD A;  1S3M A;  4O4K A;  1KBP A;  3THN A;  4UT3 A;  2CV9 A;  2USH A;  1QFC A;  3PSO A;  1OI8 A;  3QFM A;  4KKZ A;  2ZOA A;  5B8I A;  3AV0 A;  3RQZ A;  3THO B;  4WWL A;  4TUG A;  3ZU0 A;  4MOY A;  1MF8 A;  2A22 A;  3H63 A;  4ZX2 A;  2DXN A;  2O8A A;  1W24 A;  2O8G A;  4O5G A;  1II7 A;  3DW8 C;  4KBP A;  4YKE A;  3ZTV A;  4DT2 A;  4DHL A;  2DXL A;  3E7B A;  3EGG A;  3IB7 A;  3TGH A;  5JPF A;  3H69 A;  1AUI A;  1OIE A;  1XM7 A;  2NPP C;  4LAC C;  4V0W A;  3H68 A;  4JA9 A;  5F3W A;  3K7W C;  4IL1 A;  1V73 A;  3RL4 A;  3CK2 A;  5INB A;  4UWQ A;  2BQ8 X;  4V0V A;  3H62 B;  4MOV A;  4XPN A;  1XZW A;  3LL8 A;  3QFK A;  1OID A;  1T70 A;  4LU9 A;  1SU1 A;  4HD0 A;  4M0V A;  4ORB A;  4F0Z A;  3E7A A;  4FBK A;  3H66 A;  1JK7 A;  2NYM C;  5GTU A;  4ZVZ A;  2R17 A;  5JPE A;  2Z06 A;  4MP0 A;  1WAO 1;  1HP1 A;  1S3L A;  2HYP A;  2P6B A;  5C1V A;  1HPU A;  2YEQ A;  2HY1 A;  1IT6 A;  4H2B A;  4LTY A;  5JJT A;  3AUZ A;  2AHD A;  3C5W C;  4JA7 A;  2Z72 A;  3EGH A;  1Z2W A;  1Z2X A;  4V0X A;  2QFP A;  4DSY A;  1UTE A;  4TUI A;  2BDX A;  3DSC A;  2NYL C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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