3RL5A

Rat metallophosphodiesterase mpped2 h67r mutant
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
281
structure length
279
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTRSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
molecule keywords Metallophosphoesterase MPPED2
molecule tags Hydrolase
source organism Rattus norvegicus
total genus 91
structure length 279
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl5A00
2KKNA 1SU1A 5B8IA 2WDDA 2NXFA 1QHWA 2ZBMA 3DW8C 3TGHA 1USHA 4V0VA 3THNA 4DHLA 4H2BA 3GVEA 4KBPA 3RL4A 1HO5A 3JYFA 3K7VC 1HP1A 1KBPA 1M63A 1WAO1 3QFMA 4M0VA 4ORBA 1QFCA 2JOGA 1T71A 3V4YA 1HPUA 4TUIA 2IE4C 3IVEA 4NZVA 4Q7FA 3AV0A 3EGHA 4FBWA 3IB7A 2WDEA 2NYMC 1S95A 4I5LC 3N5UA 4G9JA 1T70A 3ZTVA 5EQVA 5JPEA 1G5BA 3LL8A 4O43A 3KBPA 4O5GA 2QFPA 4DSYA 2XMOA 2HYPA 1U32A 5GTUA 4H2IA 2WDFA 3H69A 3P71C 3RL3A 4O24A 3IVDA 2IAEC 3EGGA 4DT2A 2O8AA 2O8GA 2QFRA 2R17A 3RL5A 4FBQA 2CV9A 4MP0A 4I5NC 5JPFA 4JA7A 3AUZA 5IOHA 2Z1AA 1XZWA 1UTEA 2NPPC 4ZX2A 1Z2WA 1V73A 3QG5C 2QJCA 2HY1A 1S8EA 4IYPC 4XPNA 3DSCA 3QFNA 2Z06A 3CK2A 4UT3B 5C1VA 3T1IA 4H2FA 1OIDA 4UT3A 3H60A 4J6OA 4H2GA 2BQ8X 4LACC 1II7A 3H63A 3H67A 4FBKA 4KKZA 2YVTA 1OI8A 3H68A 5F3WA 1AUIA 3H62B 1NNWA 3PSNA 3QFKA 4UWQA 5HPEA 1W24A 3IB8A 4FCXA 1MF8A 2AHDA 2Z72A 3RQZA 1S3NA 5J28A 2A22A 5JJTA 3HVQA 4LTYA 4ZVZA 2GJUA 2P6BA 2USHA 4B2OA 1S3LA 3ZU0A 3H61A 4UT2A 4F0ZA 1TCOA 3H66A 4HD0A 4ORAA 1JK7A 4V0XA 3H64A 1S3MA 3FGAC 1OIEA 4IL1A 2IE3C 2HYOA 4LU9A 4MOVA 3DSDA 5INBA 2DFJA 1FJMA 4MOYA 2Q8UA 4ORCA 3C5WC 2BDXA 2BCDA 3E7AA 3E7BA 4H1YP 1IT6A 4H1SA 1S70A 3C9FA 4JA9A 4TUGA 2NYLC 4OR9A 3K7WC 4O4KA 3THOB 5DNYA 1UF3A 3ICFA 3PSOA 2WDCA 4V0WA 4WWLA 4YKEA 1XM7A 1Z2XA 3QFOA 1WARA
chains in the Genus database with same CATH superfamily
2KKNA 1SU1A 5B8IA 2WDDA 2NXFA 1QHWA 2ZBMA 3DW8C 3D03A 3TGHA 1USHA 4V0VA 3THNA 4DHLA 4H2BA 3GVEA 4KBPA 3RL4A 1HO5A 3JYFA 3K7VC 1HP1A 1KBPA 1M63A 1WAO1 3QFMA 4M0VA 4ORBA 1QFCA 2JOGA 1T71A 3V4YA 1HPUA 4TUIA 2IE4C 2DXLA 2ZOAA 3IVEA 4NZVA 4Q7FA 3AV0A 3EGHA 4FBWA 3IB7A 2WDEA 2NYMC 1S95A 4I5LC 3N5UA 4G9JA 1T70A 3ZTVA 5EQVA 5JPEA 1G5BA 3LL8A 4O43A 3KBPA 4O5GA 2QFPA 4DSYA 2XMOA 2HYPA 1U32A 5GTUA 4H2IA 2DXNA 2WDFA 3H69A 3P71C 3RL3A 4O24A 3IVDA 2IAEC 3EGGA 4DT2A 2O8AA 2O8GA 2QFRA 2R17A 3RL5A 4FBQA 2CV9A 2ZO9B 4MP0A 4I5NC 5JPFA 4JA7A 3AUZA 5IOHA 2Z1AA 1XZWA 1UTEA 2NPPC 4ZX2A 1Z2WA 1V73A 3QG5C 2QJCA 2HY1A 1S8EA 4IYPC 4XPNA 3DSCA 3QFNA 2Z06A 3CK2A 4UT3B 5C1VA 3T1IA 4H2FA 1OIDA 4UT3A 3H60A 4J6OA 4H2GA 2BQ8X 4LACC 2YEQA 1II7A 3H63A 3H67A 4FBKA 4KKZA 2YVTA 3E0JA 1OI8A 3H68A 5F3WA 1AUIA 3FLOA 3H62B 1NNWA 3PSNA 3QFKA 4UWQA 5HPEA 1W24A 3IB8A 4FCXA 1MF8A 2AHDA 2Z72A 3RQZA 1S3NA 5J28A 2A22A 5JJTA 3HVQA 4LTYA 4ZVZA 2GJUA 2P6BA 2USHA 4B2OA 1S3LA 3ZU0A 3H61A 4UT2A 4F0ZA 1TCOA 3H66A 4HD0A 4ORAA 1JK7A 4V0XA 3H64A 1S3MA 3FGAC 1OIEA 4IL1A 2IE3C 2HYOA 4LU9A 4MOVA 3DSDA 5INBA 2DFJA 1FJMA 4MOYA 2Q8UA 4ORCA 3C5WC 2BDXA 2BCDA 3E7AA 3E7BA 4H1YP 1IT6A 4H1SA 1S70A 3C9FA 4JA9A 4TUGA 2NYLC 4OR9A 3K7WC 4O4KA 3THOB 5DNYA 1UF3A 3ICFA 3PSOA 2WDCA 4V0WA 4WWLA 4YKEA 1XM7A 1Z2XA 3QFOA 1WARA
chains in the Genus database with same CATH topology
2KKNA 1SU1A 5B8IA 2WDDA 2NXFA 1QHWA 2ZBMA 3DW8C 3D03A 3TGHA 1USHA 4V0VA 3THNA 4DHLA 4H2BA 3GVEA 4KBPA 3RL4A 1HO5A 3JYFA 3K7VC 1HP1A 1KBPA 1M63A 1WAO1 3QFMA 4M0VA 4ORBA 1QFCA 2JOGA 1T71A 3V4YA 1HPUA 4TUIA 2IE4C 2DXLA 2ZOAA 3IVEA 4NZVA 4Q7FA 3AV0A 3EGHA 4FBWA 3IB7A 2WDEA 2NYMC 1S95A 4I5LC 3N5UA 4G9JA 1T70A 3ZTVA 5EQVA 5JPEA 1G5BA 3LL8A 4O43A 3KBPA 4O5GA 2QFPA 4DSYA 2XMOA 2HYPA 1U32A 5GTUA 4H2IA 2DXNA 2WDFA 3H69A 3P71C 3RL3A 4O24A 3IVDA 2IAEC 3EGGA 4DT2A 2O8AA 2O8GA 2QFRA 2R17A 3RL5A 4FBQA 2CV9A 2ZO9B 4MP0A 4I5NC 5JPFA 4JA7A 3AUZA 5IOHA 2Z1AA 1XZWA 1UTEA 2NPPC 4ZX2A 1Z2WA 1V73A 3QG5C 2QJCA 2HY1A 1S8EA 4IYPC 4XPNA 3DSCA 3QFNA 2Z06A 3CK2A 4UT3B 5C1VA 3T1IA 4H2FA 1OIDA 4UT3A 3H60A 4J6OA 4H2GA 2BQ8X 4LACC 2YEQA 1II7A 3H63A 3H67A 4FBKA 4KKZA 2YVTA 3E0JA 1OI8A 3H68A 5F3WA 1AUIA 3FLOA 3H62B 1NNWA 3PSNA 3QFKA 4UWQA 5HPEA 1W24A 3IB8A 4FCXA 1MF8A 2AHDA 2Z72A 3RQZA 1S3NA 5J28A 2A22A 5JJTA 3HVQA 4LTYA 4ZVZA 2GJUA 2P6BA 2USHA 4B2OA 1S3LA 3ZU0A 3H61A 4UT2A 4F0ZA 1TCOA 3H66A 4HD0A 4ORAA 1JK7A 4V0XA 3H64A 1S3MA 3FGAC 1OIEA 4IL1A 2IE3C 2HYOA 4LU9A 4MOVA 3DSDA 5INBA 2DFJA 1FJMA 4MOYA 2Q8UA 4ORCA 3C5WC 2BDXA 2BCDA 3E7AA 3E7BA 4H1YP 1IT6A 4H1SA 1S70A 3C9FA 4JA9A 4TUGA 2NYLC 4OR9A 3K7WC 4O4KA 3THOB 5DNYA 1UF3A 3ICFA 3PSOA 2WDCA 4V0WA 4WWLA 4YKEA 1XM7A 1Z2XA 3QFOA 1WARA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2KKN A;  1SU1 A;  5B8I A;  2WDD A;  2NXF A;  1QHW A;  2ZBM A;  3DW8 C;  3TGH A;  1USH A;  4V0V A;  3THN A;  4DHL A;  4H2B A;  3GVE A;  4KBP A;  3RL4 A;  1HO5 A;  3JYF A;  3K7V C;  1HP1 A;  1KBP A;  1M63 A;  1WAO 1;  3QFM A;  4M0V A;  4ORB A;  1QFC A;  2JOG A;  1T71 A;  3V4Y A;  1HPU A;  4TUI A;  2IE4 C;  3IVE A;  4NZV A;  4Q7F A;  3AV0 A;  3EGH A;  4FBW A;  3IB7 A;  2WDE A;  2NYM C;  1S95 A;  4I5L C;  3N5U A;  4G9J A;  1T70 A;  3ZTV A;  5EQV A;  5JPE A;  1G5B A;  3LL8 A;  4O43 A;  3KBP A;  4O5G A;  2QFP A;  4DSY A;  2XMO A;  2HYP A;  1U32 A;  5GTU A;  4H2I A;  2WDF A;  3H69 A;  3P71 C;  3RL3 A;  4O24 A;  3IVD A;  2IAE C;  3EGG A;  4DT2 A;  2O8A A;  2O8G A;  2QFR A;  2R17 A;  3RL5 A;  4FBQ A;  2CV9 A;  4MP0 A;  4I5N C;  5JPF A;  4JA7 A;  3AUZ A;  5IOH A;  2Z1A A;  1XZW A;  1UTE A;  2NPP C;  4ZX2 A;  1Z2W A;  1V73 A;  3QG5 C;  2QJC A;  2HY1 A;  1S8E A;  4IYP C;  4XPN A;  3DSC A;  3QFN A;  2Z06 A;  3CK2 A;  4UT3 B;  5C1V A;  3T1I A;  4H2F A;  1OID A;  4UT3 A;  3H60 A;  4J6O A;  4H2G A;  2BQ8 X;  4LAC C;  1II7 A;  3H63 A;  3H67 A;  4FBK A;  4KKZ A;  2YVT A;  1OI8 A;  3H68 A;  5F3W A;  1AUI A;  3H62 B;  1NNW A;  3PSN A;  3QFK A;  4UWQ A;  5HPE A;  1W24 A;  3IB8 A;  4FCX A;  1MF8 A;  2AHD A;  2Z72 A;  3RQZ A;  1S3N A;  5J28 A;  2A22 A;  5JJT A;  3HVQ A;  4LTY A;  4ZVZ A;  2GJU A;  2P6B A;  2USH A;  4B2O A;  1S3L A;  3ZU0 A;  3H61 A;  4UT2 A;  4F0Z A;  1TCO A;  3H66 A;  4HD0 A;  4ORA A;  1JK7 A;  4V0X A;  3H64 A;  1S3M A;  3FGA C;  1OIE A;  4IL1 A;  2IE3 C;  2HYO A;  4LU9 A;  4MOV A;  3DSD A;  5INB A;  2DFJ A;  1FJM A;  4MOY A;  2Q8U A;  4ORC A;  3C5W C;  2BDX A;  2BCD A;  3E7A A;  3E7B A;  4H1Y P;  1IT6 A;  4H1S A;  1S70 A;  3C9F A;  4JA9 A;  4TUG A;  2NYL C;  4OR9 A;  3K7W C;  4O4K A;  3THO B;  5DNY A;  1UF3 A;  3ICF A;  3PSO A;  2WDC A;  4V0W A;  4WWL A;  4YKE A;  1XM7 A;  1Z2X A;  3QFO A;  1WAR A; 
#chains in the Genus database with same CATH topology
 2KKN A;  1SU1 A;  5B8I A;  2WDD A;  2NXF A;  1QHW A;  2ZBM A;  3DW8 C;  3D03 A;  3TGH A;  1USH A;  4V0V A;  3THN A;  4DHL A;  4H2B A;  3GVE A;  4KBP A;  3RL4 A;  1HO5 A;  3JYF A;  3K7V C;  1HP1 A;  1KBP A;  1M63 A;  1WAO 1;  3QFM A;  4M0V A;  4ORB A;  1QFC A;  2JOG A;  1T71 A;  3V4Y A;  1HPU A;  4TUI A;  2IE4 C;  2DXL A;  2ZOA A;  3IVE A;  4NZV A;  4Q7F A;  3AV0 A;  3EGH A;  4FBW A;  3IB7 A;  2WDE A;  2NYM C;  1S95 A;  4I5L C;  3N5U A;  4G9J A;  1T70 A;  3ZTV A;  5EQV A;  5JPE A;  1G5B A;  3LL8 A;  4O43 A;  3KBP A;  4O5G A;  2QFP A;  4DSY A;  2XMO A;  2HYP A;  1U32 A;  5GTU A;  4H2I A;  2DXN A;  2WDF A;  3H69 A;  3P71 C;  3RL3 A;  4O24 A;  3IVD A;  2IAE C;  3EGG A;  4DT2 A;  2O8A A;  2O8G A;  2QFR A;  2R17 A;  3RL5 A;  4FBQ A;  2CV9 A;  2ZO9 B;  4MP0 A;  4I5N C;  5JPF A;  4JA7 A;  3AUZ A;  5IOH A;  2Z1A A;  1XZW A;  1UTE A;  2NPP C;  4ZX2 A;  1Z2W A;  1V73 A;  3QG5 C;  2QJC A;  2HY1 A;  1S8E A;  4IYP C;  4XPN A;  3DSC A;  3QFN A;  2Z06 A;  3CK2 A;  4UT3 B;  5C1V A;  3T1I A;  4H2F A;  1OID A;  4UT3 A;  3H60 A;  4J6O A;  4H2G A;  2BQ8 X;  4LAC C;  2YEQ A;  1II7 A;  3H63 A;  3H67 A;  4FBK A;  4KKZ A;  2YVT A;  3E0J A;  1OI8 A;  3H68 A;  5F3W A;  1AUI A;  3FLO A;  3H62 B;  1NNW A;  3PSN A;  3QFK A;  4UWQ A;  5HPE A;  1W24 A;  3IB8 A;  4FCX A;  1MF8 A;  2AHD A;  2Z72 A;  3RQZ A;  1S3N A;  5J28 A;  2A22 A;  5JJT A;  3HVQ A;  4LTY A;  4ZVZ A;  2GJU A;  2P6B A;  2USH A;  4B2O A;  1S3L A;  3ZU0 A;  3H61 A;  4UT2 A;  4F0Z A;  1TCO A;  3H66 A;  4HD0 A;  4ORA A;  1JK7 A;  4V0X A;  3H64 A;  1S3M A;  3FGA C;  1OIE A;  4IL1 A;  2IE3 C;  2HYO A;  4LU9 A;  4MOV A;  3DSD A;  5INB A;  2DFJ A;  1FJM A;  4MOY A;  2Q8U A;  4ORC A;  3C5W C;  2BDX A;  2BCD A;  3E7A A;  3E7B A;  4H1Y P;  1IT6 A;  4H1S A;  1S70 A;  3C9F A;  4JA9 A;  4TUG A;  2NYL C;  4OR9 A;  3K7W C;  4O4K A;  3THO B;  5DNY A;  1UF3 A;  3ICF A;  3PSO A;  2WDC A;  4V0W A;  4WWL A;  4YKE A;  1XM7 A;  1Z2X A;  3QFO A;  1WAR A; 
#chains in the Genus database with same CATH homology
 2KKN A;  1SU1 A;  5B8I A;  2WDD A;  2NXF A;  1QHW A;  2ZBM A;  3DW8 C;  3D03 A;  3TGH A;  1USH A;  4V0V A;  3THN A;  4DHL A;  4H2B A;  3GVE A;  4KBP A;  3RL4 A;  1HO5 A;  3JYF A;  3K7V C;  1HP1 A;  1KBP A;  1M63 A;  1WAO 1;  3QFM A;  4M0V A;  4ORB A;  1QFC A;  2JOG A;  1T71 A;  3V4Y A;  1HPU A;  4TUI A;  2IE4 C;  2DXL A;  2ZOA A;  3IVE A;  4NZV A;  4Q7F A;  3AV0 A;  3EGH A;  4FBW A;  3IB7 A;  2WDE A;  2NYM C;  1S95 A;  4I5L C;  3N5U A;  4G9J A;  1T70 A;  3ZTV A;  5EQV A;  5JPE A;  1G5B A;  3LL8 A;  4O43 A;  3KBP A;  4O5G A;  2QFP A;  4DSY A;  2XMO A;  2HYP A;  1U32 A;  5GTU A;  4H2I A;  2DXN A;  2WDF A;  3H69 A;  3P71 C;  3RL3 A;  4O24 A;  3IVD A;  2IAE C;  3EGG A;  4DT2 A;  2O8A A;  2O8G A;  2QFR A;  2R17 A;  3RL5 A;  4FBQ A;  2CV9 A;  2ZO9 B;  4MP0 A;  4I5N C;  5JPF A;  4JA7 A;  3AUZ A;  5IOH A;  2Z1A A;  1XZW A;  1UTE A;  2NPP C;  4ZX2 A;  1Z2W A;  1V73 A;  3QG5 C;  2QJC A;  2HY1 A;  1S8E A;  4IYP C;  4XPN A;  3DSC A;  3QFN A;  2Z06 A;  3CK2 A;  4UT3 B;  5C1V A;  3T1I A;  4H2F A;  1OID A;  4UT3 A;  3H60 A;  4J6O A;  4H2G A;  2BQ8 X;  4LAC C;  2YEQ A;  1II7 A;  3H63 A;  3H67 A;  4FBK A;  4KKZ A;  2YVT A;  3E0J A;  1OI8 A;  3H68 A;  5F3W A;  1AUI A;  3FLO A;  3H62 B;  1NNW A;  3PSN A;  3QFK A;  4UWQ A;  5HPE A;  1W24 A;  3IB8 A;  4FCX A;  1MF8 A;  2AHD A;  2Z72 A;  3RQZ A;  1S3N A;  5J28 A;  2A22 A;  5JJT A;  3HVQ A;  4LTY A;  4ZVZ A;  2GJU A;  2P6B A;  2USH A;  4B2O A;  1S3L A;  3ZU0 A;  3H61 A;  4UT2 A;  4F0Z A;  1TCO A;  3H66 A;  4HD0 A;  4ORA A;  1JK7 A;  4V0X A;  3H64 A;  1S3M A;  3FGA C;  1OIE A;  4IL1 A;  2IE3 C;  2HYO A;  4LU9 A;  4MOV A;  3DSD A;  5INB A;  2DFJ A;  1FJM A;  4MOY A;  2Q8U A;  4ORC A;  3C5W C;  2BDX A;  2BCD A;  3E7A A;  3E7B A;  4H1Y P;  1IT6 A;  4H1S A;  1S70 A;  3C9F A;  4JA9 A;  4TUG A;  2NYL C;  4OR9 A;  3K7W C;  4O4K A;  3THO B;  5DNY A;  1UF3 A;  3ICF A;  3PSO A;  2WDC A;  4V0W A;  4WWL A;  4YKE A;  1XM7 A;  1Z2X A;  3QFO A;  1WAR A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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