3RL5A

Rat metallophosphodiesterase mpped2 h67r mutant
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
281
structure length
279
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTRSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Metallophosphoesterase MPPED2
total genus 91
structure length 279
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl5A00
4XPNA 2HYPA 4H2IA 2IE3C 3QG5C 4FBQA 1S3LA 3PSOA 3JYFA 4B2OA 3H69A 4ZX2A 1KBPA 5DNYA 4J6OA 4UWQA 4H2BA 4Q7FA 4I5NC 4OR9A 3FGAC 4O4KA 3QFKA 4LU9A 3RQZA 3AV0A 2R17A 4JA7A 4UT3B 3IVEA 5IOHA 2A22A 1S95A 3RL5A 4MOYA 3E7AA 1IT6A 1MF8A 3CK2A 4WWLA 3N5UA 3RL4A 4O24A 4IYPC 1S3MA 3ZTVA 3HVQA 1XM7A 4LACC 3K7VC 1OI8A 1S3NA 1U32A 4ORAA 3C5WC 4H2FA 2BCDA 3H60A 4H1YP 4MP0A 4FCXA 2BDXA 1QFCA 1OIEA 3V4YA 3H66A 2HY1A 2O8GA 4UT3A 3IB7A 2IAEC 3IVDA 4V0WA 5J28A 4O5GA 1S70A 2QFPA 2ZBMA 1WARA 3E7BA 3GVEA 4TUGA 4ZVZA 5JPEA 3P71C 3ICFA 4NZVA 5B8IA 1V73A 3AUZA 2WDFA 2YVTA 1WAO1 1II7A 1AUIA 1USHA 2DFJA 2QJCA 5EQVA 3RL3A 3K7WC 3C9FA 1HO5A 3EGHA 5C1VA 2AHDA 2HYOA 3LL8A 3ZU0A 4FBWA 1JK7A 1SU1A 2P6BA 5HPEA 4F0ZA 4KKZA 3QFMA 3KBPA 1HP1A 1NNWA 2NYMC 3QFOA 4JA9A 1S8EA 1T71A 2O8AA 4O43A 1Z2XA 2Q8UA 4DSYA 3IB8A 2QFRA 1HPUA 4G9JA 2Z72A 3EGGA 2IE4C 4ORBA 4ORCA 1T70A 4UT2A 2XMOA 5GTUA 3T1IA 3DSCA 1W24A 3H64A 2USHA 2WDEA 3H67A 1G5BA 4H2GA 3QFNA 2Z1AA 1UF3A 1XZWA 2NXFA 4LTYA 2JOGA 5JJTA 2BQ8X 3H61A 4V0XA 4YKEA 3THOB 3H63A 3H68A 2WDCA 4DHLA 2WDDA 4V0VA 4TUIA 3H62B 3TGHA 2NPPC 1QHWA 1TCOA 2CV9A 1FJMA 2GJUA 5F3WA 1OIDA 4FBKA 4M0VA 4KBPA 4HD0A 1UTEA 4IL1A 4I5LC 3DSDA 1M63A 3THNA 5INBA 1Z2WA 2Z06A 4H1SA 4MOVA 4DT2A 5JPFA 3DW8C 2KKNA 3PSNA 2NYLC
chains in the Genus database with same CATH superfamily
4XPNA 2HYPA 4H2IA 2IE3C 3QG5C 4FBQA 1S3LA 3PSOA 3JYFA 4B2OA 3H69A 4ZX2A 1KBPA 5DNYA 4J6OA 4UWQA 4H2BA 4Q7FA 4I5NC 4OR9A 3FGAC 4O4KA 3QFKA 4LU9A 3RQZA 3AV0A 2R17A 4JA7A 4UT3B 3E0JA 3IVEA 5IOHA 2A22A 1S95A 3RL5A 4MOYA 3E7AA 1IT6A 1MF8A 3CK2A 4WWLA 3N5UA 3RL4A 4O24A 4IYPC 1S3MA 3ZTVA 3HVQA 1XM7A 3FLOA 4LACC 3K7VC 1OI8A 1S3NA 1U32A 4ORAA 3C5WC 4H2FA 2BCDA 3H60A 4H1YP 4MP0A 4FCXA 2DXLA 2BDXA 2DXNA 1QFCA 1OIEA 3V4YA 3H66A 2HY1A 2O8GA 4UT3A 3IB7A 2IAEC 3IVDA 4V0WA 5J28A 4O5GA 1S70A 2QFPA 2ZBMA 1WARA 3E7BA 3GVEA 4TUGA 4ZVZA 5JPEA 3P71C 3ICFA 4NZVA 5B8IA 1V73A 3AUZA 2WDFA 2YVTA 1WAO1 1II7A 1AUIA 1USHA 2DFJA 2QJCA 3D03A 5EQVA 3RL3A 3K7WC 3C9FA 2ZOAA 1HO5A 3EGHA 5C1VA 2AHDA 2HYOA 3LL8A 3ZU0A 4FBWA 1JK7A 1SU1A 2P6BA 5HPEA 4F0ZA 4KKZA 3QFMA 3KBPA 1HP1A 1NNWA 2NYMC 3QFOA 4JA9A 1S8EA 1T71A 2O8AA 4O43A 1Z2XA 2Q8UA 4DSYA 3IB8A 2QFRA 1HPUA 4G9JA 2Z72A 3EGGA 2IE4C 4ORBA 4ORCA 1T70A 4UT2A 2XMOA 5GTUA 3T1IA 3DSCA 1W24A 3H64A 2USHA 2WDEA 3H67A 1G5BA 4H2GA 3QFNA 2Z1AA 1UF3A 1XZWA 2NXFA 4LTYA 2JOGA 5JJTA 2BQ8X 3H61A 4V0XA 4YKEA 3THOB 3H63A 3H68A 2WDCA 4DHLA 2WDDA 4V0VA 4TUIA 3H62B 3TGHA 2NPPC 1QHWA 1TCOA 2CV9A 1FJMA 2GJUA 5F3WA 1OIDA 4FBKA 4M0VA 4KBPA 4HD0A 1UTEA 4IL1A 4I5LC 3DSDA 2ZO9B 1M63A 3THNA 2YEQA 1Z2WA 2Z06A 4H1SA 4MOVA 4DT2A 5INBA 3DW8C 5JPFA 2KKNA 3PSNA 2NYLC
chains in the Genus database with same CATH topology
4XPNA 2HYPA 4H2IA 2IE3C 3QG5C 4FBQA 1S3LA 3PSOA 3JYFA 4B2OA 3H69A 4ZX2A 1KBPA 5DNYA 4J6OA 4UWQA 4H2BA 4Q7FA 4I5NC 4OR9A 3FGAC 4O4KA 3QFKA 4LU9A 3RQZA 3AV0A 2R17A 4JA7A 4UT3B 3E0JA 3IVEA 5IOHA 2A22A 1S95A 3RL5A 4MOYA 3E7AA 1IT6A 1MF8A 3CK2A 4WWLA 3N5UA 3RL4A 4O24A 4IYPC 1S3MA 3ZTVA 3HVQA 1XM7A 3FLOA 4LACC 3K7VC 1OI8A 1S3NA 1U32A 4ORAA 3C5WC 4H2FA 2BCDA 3H60A 4H1YP 4MP0A 4FCXA 2DXLA 2BDXA 2DXNA 1QFCA 1OIEA 3V4YA 3H66A 2HY1A 2O8GA 4UT3A 3IB7A 2IAEC 3IVDA 4V0WA 5J28A 4O5GA 1S70A 2QFPA 2ZBMA 1WARA 3E7BA 3GVEA 4TUGA 4ZVZA 5JPEA 3P71C 3ICFA 4NZVA 5B8IA 1V73A 3AUZA 2WDFA 2YVTA 1WAO1 1II7A 1AUIA 1USHA 2DFJA 2QJCA 3D03A 5EQVA 3RL3A 3K7WC 3C9FA 2ZOAA 1HO5A 3EGHA 5C1VA 2AHDA 2HYOA 3LL8A 3ZU0A 4FBWA 1JK7A 1SU1A 2P6BA 5HPEA 4F0ZA 4KKZA 3QFMA 3KBPA 1HP1A 1NNWA 2NYMC 3QFOA 4JA9A 1S8EA 1T71A 2O8AA 4O43A 1Z2XA 2Q8UA 4DSYA 3IB8A 2QFRA 1HPUA 4G9JA 2Z72A 3EGGA 2IE4C 4ORBA 4ORCA 1T70A 4UT2A 2XMOA 5GTUA 3T1IA 3DSCA 1W24A 3H64A 2USHA 2WDEA 3H67A 1G5BA 4H2GA 3QFNA 2Z1AA 1UF3A 1XZWA 2NXFA 4LTYA 2JOGA 5JJTA 2BQ8X 3H61A 4V0XA 4YKEA 3THOB 3H63A 3H68A 2WDCA 4DHLA 2WDDA 4V0VA 4TUIA 3H62B 3TGHA 2NPPC 1QHWA 1TCOA 2CV9A 1FJMA 2GJUA 5F3WA 1OIDA 4FBKA 4M0VA 4KBPA 4HD0A 1UTEA 4IL1A 4I5LC 3DSDA 2ZO9B 1M63A 3THNA 2YEQA 1Z2WA 2Z06A 4H1SA 4MOVA 4DT2A 5INBA 3DW8C 5JPFA 2KKNA 3PSNA 2NYLC
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4XPN A;  2HYP A;  4H2I A;  2IE3 C;  3QG5 C;  4FBQ A;  1S3L A;  3PSO A;  3JYF A;  4B2O A;  3H69 A;  4ZX2 A;  1KBP A;  5DNY A;  4J6O A;  4UWQ A;  4H2B A;  4Q7F A;  4I5N C;  4OR9 A;  3FGA C;  4O4K A;  3QFK A;  4LU9 A;  3RQZ A;  3AV0 A;  2R17 A;  4JA7 A;  4UT3 B;  3IVE A;  5IOH A;  2A22 A;  1S95 A;  3RL5 A;  4MOY A;  3E7A A;  1IT6 A;  1MF8 A;  3CK2 A;  4WWL A;  3N5U A;  3RL4 A;  4O24 A;  4IYP C;  1S3M A;  3ZTV A;  3HVQ A;  1XM7 A;  4LAC C;  3K7V C;  1OI8 A;  1S3N A;  1U32 A;  4ORA A;  3C5W C;  4H2F A;  2BCD A;  3H60 A;  4H1Y P;  4MP0 A;  4FCX A;  2BDX A;  1QFC A;  1OIE A;  3V4Y A;  3H66 A;  2HY1 A;  2O8G A;  4UT3 A;  3IB7 A;  2IAE C;  3IVD A;  4V0W A;  5J28 A;  4O5G A;  1S70 A;  2QFP A;  2ZBM A;  1WAR A;  3E7B A;  3GVE A;  4TUG A;  4ZVZ A;  5JPE A;  3P71 C;  3ICF A;  4NZV A;  5B8I A;  1V73 A;  3AUZ A;  2WDF A;  2YVT A;  1WAO 1;  1II7 A;  1AUI A;  1USH A;  2DFJ A;  2QJC A;  5EQV A;  3RL3 A;  3K7W C;  3C9F A;  1HO5 A;  3EGH A;  5C1V A;  2AHD A;  2HYO A;  3LL8 A;  3ZU0 A;  4FBW A;  1JK7 A;  1SU1 A;  2P6B A;  5HPE A;  4F0Z A;  4KKZ A;  3QFM A;  3KBP A;  1HP1 A;  1NNW A;  2NYM C;  3QFO A;  4JA9 A;  1S8E A;  1T71 A;  2O8A A;  4O43 A;  1Z2X A;  2Q8U A;  4DSY A;  3IB8 A;  2QFR A;  1HPU A;  4G9J A;  2Z72 A;  3EGG A;  2IE4 C;  4ORB A;  4ORC A;  1T70 A;  4UT2 A;  2XMO A;  5GTU A;  3T1I A;  3DSC A;  1W24 A;  3H64 A;  2USH A;  2WDE A;  3H67 A;  1G5B A;  4H2G A;  3QFN A;  2Z1A A;  1UF3 A;  1XZW A;  2NXF A;  4LTY A;  2JOG A;  5JJT A;  2BQ8 X;  3H61 A;  4V0X A;  4YKE A;  3THO B;  3H63 A;  3H68 A;  2WDC A;  4DHL A;  2WDD A;  4V0V A;  4TUI A;  3H62 B;  3TGH A;  2NPP C;  1QHW A;  1TCO A;  2CV9 A;  1FJM A;  2GJU A;  5F3W A;  1OID A;  4FBK A;  4M0V A;  4KBP A;  4HD0 A;  1UTE A;  4IL1 A;  4I5L C;  3DSD A;  1M63 A;  3THN A;  5INB A;  1Z2W A;  2Z06 A;  4H1S A;  4MOV A;  4DT2 A;  5JPF A;  3DW8 C;  2KKN A;  3PSN A;  2NYL C; 
#chains in the Genus database with same CATH topology
 4XPN A;  2HYP A;  4H2I A;  2IE3 C;  3QG5 C;  4FBQ A;  1S3L A;  3PSO A;  3JYF A;  4B2O A;  3H69 A;  4ZX2 A;  1KBP A;  5DNY A;  4J6O A;  4UWQ A;  4H2B A;  4Q7F A;  4I5N C;  4OR9 A;  3FGA C;  4O4K A;  3QFK A;  4LU9 A;  3RQZ A;  3AV0 A;  2R17 A;  4JA7 A;  4UT3 B;  3E0J A;  3IVE A;  5IOH A;  2A22 A;  1S95 A;  3RL5 A;  4MOY A;  3E7A A;  1IT6 A;  1MF8 A;  3CK2 A;  4WWL A;  3N5U A;  3RL4 A;  4O24 A;  4IYP C;  1S3M A;  3ZTV A;  3HVQ A;  1XM7 A;  3FLO A;  4LAC C;  3K7V C;  1OI8 A;  1S3N A;  1U32 A;  4ORA A;  3C5W C;  4H2F A;  2BCD A;  3H60 A;  4H1Y P;  4MP0 A;  4FCX A;  2DXL A;  2BDX A;  2DXN A;  1QFC A;  1OIE A;  3V4Y A;  3H66 A;  2HY1 A;  2O8G A;  4UT3 A;  3IB7 A;  2IAE C;  3IVD A;  4V0W A;  5J28 A;  4O5G A;  1S70 A;  2QFP A;  2ZBM A;  1WAR A;  3E7B A;  3GVE A;  4TUG A;  4ZVZ A;  5JPE A;  3P71 C;  3ICF A;  4NZV A;  5B8I A;  1V73 A;  3AUZ A;  2WDF A;  2YVT A;  1WAO 1;  1II7 A;  1AUI A;  1USH A;  2DFJ A;  2QJC A;  3D03 A;  5EQV A;  3RL3 A;  3K7W C;  3C9F A;  2ZOA A;  1HO5 A;  3EGH A;  5C1V A;  2AHD A;  2HYO A;  3LL8 A;  3ZU0 A;  4FBW A;  1JK7 A;  1SU1 A;  2P6B A;  5HPE A;  4F0Z A;  4KKZ A;  3QFM A;  3KBP A;  1HP1 A;  1NNW A;  2NYM C;  3QFO A;  4JA9 A;  1S8E A;  1T71 A;  2O8A A;  4O43 A;  1Z2X A;  2Q8U A;  4DSY A;  3IB8 A;  2QFR A;  1HPU A;  4G9J A;  2Z72 A;  3EGG A;  2IE4 C;  4ORB A;  4ORC A;  1T70 A;  4UT2 A;  2XMO A;  5GTU A;  3T1I A;  3DSC A;  1W24 A;  3H64 A;  2USH A;  2WDE A;  3H67 A;  1G5B A;  4H2G A;  3QFN A;  2Z1A A;  1UF3 A;  1XZW A;  2NXF A;  4LTY A;  2JOG A;  5JJT A;  2BQ8 X;  3H61 A;  4V0X A;  4YKE A;  3THO B;  3H63 A;  3H68 A;  2WDC A;  4DHL A;  2WDD A;  4V0V A;  4TUI A;  3H62 B;  3TGH A;  2NPP C;  1QHW A;  1TCO A;  2CV9 A;  1FJM A;  2GJU A;  5F3W A;  1OID A;  4FBK A;  4M0V A;  4KBP A;  4HD0 A;  1UTE A;  4IL1 A;  4I5L C;  3DSD A;  2ZO9 B;  1M63 A;  3THN A;  2YEQ A;  1Z2W A;  2Z06 A;  4H1S A;  4MOV A;  4DT2 A;  5INB A;  3DW8 C;  5JPF A;  2KKN A;  3PSN A;  2NYL C; 
#chains in the Genus database with same CATH homology
 4XPN A;  2HYP A;  4H2I A;  2IE3 C;  3QG5 C;  4FBQ A;  1S3L A;  3PSO A;  3JYF A;  4B2O A;  3H69 A;  4ZX2 A;  1KBP A;  5DNY A;  4J6O A;  4UWQ A;  4H2B A;  4Q7F A;  4I5N C;  4OR9 A;  3FGA C;  4O4K A;  3QFK A;  4LU9 A;  3RQZ A;  3AV0 A;  2R17 A;  4JA7 A;  4UT3 B;  3E0J A;  3IVE A;  5IOH A;  2A22 A;  1S95 A;  3RL5 A;  4MOY A;  3E7A A;  1IT6 A;  1MF8 A;  3CK2 A;  4WWL A;  3N5U A;  3RL4 A;  4O24 A;  4IYP C;  1S3M A;  3ZTV A;  3HVQ A;  1XM7 A;  3FLO A;  4LAC C;  3K7V C;  1OI8 A;  1S3N A;  1U32 A;  4ORA A;  3C5W C;  4H2F A;  2BCD A;  3H60 A;  4H1Y P;  4MP0 A;  4FCX A;  2DXL A;  2BDX A;  2DXN A;  1QFC A;  1OIE A;  3V4Y A;  3H66 A;  2HY1 A;  2O8G A;  4UT3 A;  3IB7 A;  2IAE C;  3IVD A;  4V0W A;  5J28 A;  4O5G A;  1S70 A;  2QFP A;  2ZBM A;  1WAR A;  3E7B A;  3GVE A;  4TUG A;  4ZVZ A;  5JPE A;  3P71 C;  3ICF A;  4NZV A;  5B8I A;  1V73 A;  3AUZ A;  2WDF A;  2YVT A;  1WAO 1;  1II7 A;  1AUI A;  1USH A;  2DFJ A;  2QJC A;  3D03 A;  5EQV A;  3RL3 A;  3K7W C;  3C9F A;  2ZOA A;  1HO5 A;  3EGH A;  5C1V A;  2AHD A;  2HYO A;  3LL8 A;  3ZU0 A;  4FBW A;  1JK7 A;  1SU1 A;  2P6B A;  5HPE A;  4F0Z A;  4KKZ A;  3QFM A;  3KBP A;  1HP1 A;  1NNW A;  2NYM C;  3QFO A;  4JA9 A;  1S8E A;  1T71 A;  2O8A A;  4O43 A;  1Z2X A;  2Q8U A;  4DSY A;  3IB8 A;  2QFR A;  1HPU A;  4G9J A;  2Z72 A;  3EGG A;  2IE4 C;  4ORB A;  4ORC A;  1T70 A;  4UT2 A;  2XMO A;  5GTU A;  3T1I A;  3DSC A;  1W24 A;  3H64 A;  2USH A;  2WDE A;  3H67 A;  1G5B A;  4H2G A;  3QFN A;  2Z1A A;  1UF3 A;  1XZW A;  2NXF A;  4LTY A;  2JOG A;  5JJT A;  2BQ8 X;  3H61 A;  4V0X A;  4YKE A;  3THO B;  3H63 A;  3H68 A;  2WDC A;  4DHL A;  2WDD A;  4V0V A;  4TUI A;  3H62 B;  3TGH A;  2NPP C;  1QHW A;  1TCO A;  2CV9 A;  1FJM A;  2GJU A;  5F3W A;  1OID A;  4FBK A;  4M0V A;  4KBP A;  4HD0 A;  1UTE A;  4IL1 A;  4I5L C;  3DSD A;  2ZO9 B;  1M63 A;  3THN A;  2YEQ A;  1Z2W A;  2Z06 A;  4H1S A;  4MOV A;  4DT2 A;  5INB A;  3DW8 C;  5JPF A;  2KKN A;  3PSN A;  2NYL C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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