3RL5A

Rat metallophosphodiesterase mpped2 h67r mutant
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
281
structure length
279
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTRSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
molecule keywords Metallophosphoesterase MPPED2
molecule tags Hydrolase
source organism Rattus norvegicus
total genus 91
structure length 279
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl5A00
3EGHA 2JOGA 2QFRA 4UWQA 4H2FA 5C1VA 3H62B 1HP1A 2BCDA 4H2BA 1M63A 3TGHA 4XPNA 4YKEA 3QG5C 4LTYA 1V73A 4ORAA 1WARA 1FJMA 3EGGA 4LACC 4MOVA 4UT3A 3RL4A 2NYMC 2O8AA 2CV9A 4ORCA 4M0VA 2IE4C 3AV0A 4H1YP 2NPPC 5EQVA 1T70A 4J6OA 2QFPA 2Z1AA 4O43A 4UT3B 3IB8A 3QFMA 3N5UA 2YVTA 2XMOA 3CK2A 1S70A 1XZWA 2WDDA 5HPEA 2IE3C 4DT2A 1S8EA 4ZVZA 3RQZA 1Z2WA 4FBQA 4B2OA 3C5WC 3IVDA 1TCOA 1IT6A 1T71A 4F0ZA 1G5BA 2A22A 4WWLA 4V0VA 1UTEA 5F3WA 4KKZA 1S3MA 3QFOA 3K7VC 4TUGA 3PSOA 4O5GA 5JJTA 4H2IA 2USHA 2GJUA 3IVEA 4V0WA 3H68A 3THOB 3H61A 5JPFA 2WDFA 3DW8C 3H66A 3H63A 3P71C 2WDCA 2QJCA 3PSNA 5DNYA 1NNWA 2BDXA 4OR9A 1KBPA 5J28A 1MF8A 3QFKA 1WAO1 2HYOA 4O24A 3E7BA 4Q7FA 2DFJA 4MP0A 3E7AA 1OI8A 2Q8UA 3ZTVA 3DSCA 2WDEA 1Z2XA 4DSYA 1QFCA 4UT2A 3QFNA 4TUIA 2KKNA 3LL8A 4MOYA 2NYLC 5INBA 4NZVA 1W24A 1UF3A 3RL3A 3H67A 2IAEC 1SU1A 3H60A 3H64A 4ORBA 2HY1A 1U32A 4JA9A 3V4YA 3DSDA 5GTUA 4H2GA 4FBKA 2ZBMA 4FBWA 5B8IA 3C9FA 1II7A 3ZU0A 4O4KA 1USHA 4ZX2A 2O8GA 3GVEA 4KBPA 1S3NA 2HYPA 1JK7A 4I5LC 2BQ8X 1HO5A 4IYPC 1S95A 5JPEA 2AHDA 3IB7A 3KBPA 1AUIA 1OIDA 5IOHA 3H69A 3T1IA 4G9JA 3HVQA 3AUZA 4LU9A 2R17A 3THNA 1HPUA 2Z06A 3ICFA 1XM7A 4DHLA 3FGAC 4H1SA 2P6BA 2NXFA 4IL1A 4HD0A 4JA7A 1OIEA 1QHWA 4V0XA 2Z72A 1S3LA 3K7WC 4FCXA 4I5NC 3RL5A 3JYFA
chains in the Genus database with same CATH superfamily
3EGHA 2JOGA 2QFRA 4UWQA 4H2FA 5C1VA 3H62B 1HP1A 2DXLA 2BCDA 2ZOAA 4H2BA 1M63A 3TGHA 4XPNA 4YKEA 3QG5C 4LTYA 1V73A 4ORAA 1WARA 1FJMA 3EGGA 4LACC 4MOVA 4UT3A 3RL4A 2NYMC 2O8AA 2CV9A 4ORCA 4M0VA 2IE4C 3AV0A 4H1YP 2NPPC 5EQVA 1T70A 4J6OA 2QFPA 2Z1AA 4O43A 4UT3B 3IB8A 3QFMA 3N5UA 2YVTA 2XMOA 3CK2A 3E0JA 1S70A 1XZWA 2WDDA 5HPEA 2IE3C 4DT2A 1S8EA 4ZVZA 3RQZA 1Z2WA 4FBQA 4B2OA 3C5WC 3IVDA 3D03A 1TCOA 1IT6A 1T71A 4F0ZA 1G5BA 2A22A 4WWLA 4V0VA 1UTEA 5F3WA 4KKZA 1S3MA 3QFOA 3K7VC 4TUGA 3PSOA 4O5GA 5JJTA 4H2IA 2USHA 2DXNA 2GJUA 3IVEA 4V0WA 3H68A 3THOB 3H61A 5JPFA 2WDFA 3DW8C 3H66A 3H63A 3P71C 2WDCA 2QJCA 3PSNA 5DNYA 1NNWA 2BDXA 4OR9A 1KBPA 5J28A 1MF8A 3QFKA 1WAO1 2HYOA 4O24A 3E7BA 4Q7FA 2DFJA 2YEQA 3E7AA 1OI8A 2Q8UA 4MP0A 3ZTVA 3DSCA 2WDEA 1Z2XA 4DSYA 1QFCA 4UT2A 3QFNA 4TUIA 2KKNA 3LL8A 4MOYA 2NYLC 5INBA 4NZVA 1W24A 1UF3A 3RL3A 3H67A 2IAEC 1SU1A 3H60A 3H64A 4ORBA 2HY1A 1U32A 4JA9A 3V4YA 3DSDA 5GTUA 4H2GA 4FBKA 2ZBMA 4FBWA 5B8IA 3C9FA 1II7A 3ZU0A 4O4KA 1USHA 4ZX2A 2O8GA 3GVEA 4KBPA 1S3NA 2HYPA 1JK7A 4I5LC 2BQ8X 1HO5A 4IYPC 1S95A 5JPEA 2AHDA 3IB7A 3KBPA 1AUIA 1OIDA 5IOHA 3H69A 3T1IA 4G9JA 3HVQA 3AUZA 4LU9A 2R17A 3THNA 1HPUA 2Z06A 3FLOA 3ICFA 1XM7A 4DHLA 3FGAC 4H1SA 2P6BA 2NXFA 4IL1A 4HD0A 4JA7A 1OIEA 1QHWA 4V0XA 2Z72A 1S3LA 3K7WC 2ZO9B 4FCXA 4I5NC 3RL5A 3JYFA
chains in the Genus database with same CATH topology
3EGHA 2JOGA 2QFRA 4UWQA 4H2FA 5C1VA 3H62B 1HP1A 2DXLA 2BCDA 2ZOAA 4H2BA 1M63A 3TGHA 4XPNA 4YKEA 3QG5C 4LTYA 1V73A 4ORAA 1WARA 1FJMA 3EGGA 4LACC 4MOVA 4UT3A 3RL4A 2NYMC 2O8AA 2CV9A 4ORCA 4M0VA 2IE4C 3AV0A 4H1YP 2NPPC 5EQVA 1T70A 4J6OA 2QFPA 2Z1AA 4O43A 4UT3B 3IB8A 3QFMA 3N5UA 2YVTA 2XMOA 3CK2A 3E0JA 1S70A 1XZWA 2WDDA 5HPEA 2IE3C 4DT2A 1S8EA 4ZVZA 3RQZA 1Z2WA 4FBQA 4B2OA 3C5WC 3IVDA 3D03A 1TCOA 1IT6A 1T71A 4F0ZA 1G5BA 2A22A 4WWLA 4V0VA 1UTEA 5F3WA 4KKZA 1S3MA 3QFOA 3K7VC 4TUGA 3PSOA 4O5GA 5JJTA 4H2IA 2USHA 2DXNA 2GJUA 3IVEA 4V0WA 3H68A 3THOB 3H61A 5JPFA 2WDFA 3DW8C 3H66A 3H63A 3P71C 2WDCA 2QJCA 3PSNA 5DNYA 1NNWA 2BDXA 4OR9A 1KBPA 5J28A 1MF8A 3QFKA 1WAO1 2HYOA 4O24A 3E7BA 4Q7FA 2DFJA 2YEQA 3E7AA 1OI8A 2Q8UA 4MP0A 3ZTVA 3DSCA 2WDEA 1Z2XA 4DSYA 1QFCA 4UT2A 3QFNA 4TUIA 2KKNA 3LL8A 4MOYA 2NYLC 5INBA 4NZVA 1W24A 1UF3A 3RL3A 3H67A 2IAEC 1SU1A 3H60A 3H64A 4ORBA 2HY1A 1U32A 4JA9A 3V4YA 3DSDA 5GTUA 4H2GA 4FBKA 2ZBMA 4FBWA 5B8IA 3C9FA 1II7A 3ZU0A 4O4KA 1USHA 4ZX2A 2O8GA 3GVEA 4KBPA 1S3NA 2HYPA 1JK7A 4I5LC 2BQ8X 1HO5A 4IYPC 1S95A 5JPEA 2AHDA 3IB7A 3KBPA 1AUIA 1OIDA 5IOHA 3H69A 3T1IA 4G9JA 3HVQA 3AUZA 4LU9A 2R17A 3THNA 1HPUA 2Z06A 3FLOA 3ICFA 1XM7A 4DHLA 3FGAC 4H1SA 2P6BA 2NXFA 4IL1A 4HD0A 4JA7A 1OIEA 1QHWA 4V0XA 2Z72A 1S3LA 3K7WC 2ZO9B 4FCXA 4I5NC 3RL5A 3JYFA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3EGH A;  2JOG A;  2QFR A;  4UWQ A;  4H2F A;  5C1V A;  3H62 B;  1HP1 A;  2BCD A;  4H2B A;  1M63 A;  3TGH A;  4XPN A;  4YKE A;  3QG5 C;  4LTY A;  1V73 A;  4ORA A;  1WAR A;  1FJM A;  3EGG A;  4LAC C;  4MOV A;  4UT3 A;  3RL4 A;  2NYM C;  2O8A A;  2CV9 A;  4ORC A;  4M0V A;  2IE4 C;  3AV0 A;  4H1Y P;  2NPP C;  5EQV A;  1T70 A;  4J6O A;  2QFP A;  2Z1A A;  4O43 A;  4UT3 B;  3IB8 A;  3QFM A;  3N5U A;  2YVT A;  2XMO A;  3CK2 A;  1S70 A;  1XZW A;  2WDD A;  5HPE A;  2IE3 C;  4DT2 A;  1S8E A;  4ZVZ A;  3RQZ A;  1Z2W A;  4FBQ A;  4B2O A;  3C5W C;  3IVD A;  1TCO A;  1IT6 A;  1T71 A;  4F0Z A;  1G5B A;  2A22 A;  4WWL A;  4V0V A;  1UTE A;  5F3W A;  4KKZ A;  1S3M A;  3QFO A;  3K7V C;  4TUG A;  3PSO A;  4O5G A;  5JJT A;  4H2I A;  2USH A;  2GJU A;  3IVE A;  4V0W A;  3H68 A;  3THO B;  3H61 A;  5JPF A;  2WDF A;  3DW8 C;  3H66 A;  3H63 A;  3P71 C;  2WDC A;  2QJC A;  3PSN A;  5DNY A;  1NNW A;  2BDX A;  4OR9 A;  1KBP A;  5J28 A;  1MF8 A;  3QFK A;  1WAO 1;  2HYO A;  4O24 A;  3E7B A;  4Q7F A;  2DFJ A;  4MP0 A;  3E7A A;  1OI8 A;  2Q8U A;  3ZTV A;  3DSC A;  2WDE A;  1Z2X A;  4DSY A;  1QFC A;  4UT2 A;  3QFN A;  4TUI A;  2KKN A;  3LL8 A;  4MOY A;  2NYL C;  5INB A;  4NZV A;  1W24 A;  1UF3 A;  3RL3 A;  3H67 A;  2IAE C;  1SU1 A;  3H60 A;  3H64 A;  4ORB A;  2HY1 A;  1U32 A;  4JA9 A;  3V4Y A;  3DSD A;  5GTU A;  4H2G A;  4FBK A;  2ZBM A;  4FBW A;  5B8I A;  3C9F A;  1II7 A;  3ZU0 A;  4O4K A;  1USH A;  4ZX2 A;  2O8G A;  3GVE A;  4KBP A;  1S3N A;  2HYP A;  1JK7 A;  4I5L C;  2BQ8 X;  1HO5 A;  4IYP C;  1S95 A;  5JPE A;  2AHD A;  3IB7 A;  3KBP A;  1AUI A;  1OID A;  5IOH A;  3H69 A;  3T1I A;  4G9J A;  3HVQ A;  3AUZ A;  4LU9 A;  2R17 A;  3THN A;  1HPU A;  2Z06 A;  3ICF A;  1XM7 A;  4DHL A;  3FGA C;  4H1S A;  2P6B A;  2NXF A;  4IL1 A;  4HD0 A;  4JA7 A;  1OIE A;  1QHW A;  4V0X A;  2Z72 A;  1S3L A;  3K7W C;  4FCX A;  4I5N C;  3RL5 A;  3JYF A; 
#chains in the Genus database with same CATH topology
 3EGH A;  2JOG A;  2QFR A;  4UWQ A;  4H2F A;  5C1V A;  3H62 B;  1HP1 A;  2DXL A;  2BCD A;  2ZOA A;  4H2B A;  1M63 A;  3TGH A;  4XPN A;  4YKE A;  3QG5 C;  4LTY A;  1V73 A;  4ORA A;  1WAR A;  1FJM A;  3EGG A;  4LAC C;  4MOV A;  4UT3 A;  3RL4 A;  2NYM C;  2O8A A;  2CV9 A;  4ORC A;  4M0V A;  2IE4 C;  3AV0 A;  4H1Y P;  2NPP C;  5EQV A;  1T70 A;  4J6O A;  2QFP A;  2Z1A A;  4O43 A;  4UT3 B;  3IB8 A;  3QFM A;  3N5U A;  2YVT A;  2XMO A;  3CK2 A;  3E0J A;  1S70 A;  1XZW A;  2WDD A;  5HPE A;  2IE3 C;  4DT2 A;  1S8E A;  4ZVZ A;  3RQZ A;  1Z2W A;  4FBQ A;  4B2O A;  3C5W C;  3IVD A;  3D03 A;  1TCO A;  1IT6 A;  1T71 A;  4F0Z A;  1G5B A;  2A22 A;  4WWL A;  4V0V A;  1UTE A;  5F3W A;  4KKZ A;  1S3M A;  3QFO A;  3K7V C;  4TUG A;  3PSO A;  4O5G A;  5JJT A;  4H2I A;  2USH A;  2DXN A;  2GJU A;  3IVE A;  4V0W A;  3H68 A;  3THO B;  3H61 A;  5JPF A;  2WDF A;  3DW8 C;  3H66 A;  3H63 A;  3P71 C;  2WDC A;  2QJC A;  3PSN A;  5DNY A;  1NNW A;  2BDX A;  4OR9 A;  1KBP A;  5J28 A;  1MF8 A;  3QFK A;  1WAO 1;  2HYO A;  4O24 A;  3E7B A;  4Q7F A;  2DFJ A;  2YEQ A;  3E7A A;  1OI8 A;  2Q8U A;  4MP0 A;  3ZTV A;  3DSC A;  2WDE A;  1Z2X A;  4DSY A;  1QFC A;  4UT2 A;  3QFN A;  4TUI A;  2KKN A;  3LL8 A;  4MOY A;  2NYL C;  5INB A;  4NZV A;  1W24 A;  1UF3 A;  3RL3 A;  3H67 A;  2IAE C;  1SU1 A;  3H60 A;  3H64 A;  4ORB A;  2HY1 A;  1U32 A;  4JA9 A;  3V4Y A;  3DSD A;  5GTU A;  4H2G A;  4FBK A;  2ZBM A;  4FBW A;  5B8I A;  3C9F A;  1II7 A;  3ZU0 A;  4O4K A;  1USH A;  4ZX2 A;  2O8G A;  3GVE A;  4KBP A;  1S3N A;  2HYP A;  1JK7 A;  4I5L C;  2BQ8 X;  1HO5 A;  4IYP C;  1S95 A;  5JPE A;  2AHD A;  3IB7 A;  3KBP A;  1AUI A;  1OID A;  5IOH A;  3H69 A;  3T1I A;  4G9J A;  3HVQ A;  3AUZ A;  4LU9 A;  2R17 A;  3THN A;  1HPU A;  2Z06 A;  3FLO A;  3ICF A;  1XM7 A;  4DHL A;  3FGA C;  4H1S A;  2P6B A;  2NXF A;  4IL1 A;  4HD0 A;  4JA7 A;  1OIE A;  1QHW A;  4V0X A;  2Z72 A;  1S3L A;  3K7W C;  2ZO9 B;  4FCX A;  4I5N C;  3RL5 A;  3JYF A; 
#chains in the Genus database with same CATH homology
 3EGH A;  2JOG A;  2QFR A;  4UWQ A;  4H2F A;  5C1V A;  3H62 B;  1HP1 A;  2DXL A;  2BCD A;  2ZOA A;  4H2B A;  1M63 A;  3TGH A;  4XPN A;  4YKE A;  3QG5 C;  4LTY A;  1V73 A;  4ORA A;  1WAR A;  1FJM A;  3EGG A;  4LAC C;  4MOV A;  4UT3 A;  3RL4 A;  2NYM C;  2O8A A;  2CV9 A;  4ORC A;  4M0V A;  2IE4 C;  3AV0 A;  4H1Y P;  2NPP C;  5EQV A;  1T70 A;  4J6O A;  2QFP A;  2Z1A A;  4O43 A;  4UT3 B;  3IB8 A;  3QFM A;  3N5U A;  2YVT A;  2XMO A;  3CK2 A;  3E0J A;  1S70 A;  1XZW A;  2WDD A;  5HPE A;  2IE3 C;  4DT2 A;  1S8E A;  4ZVZ A;  3RQZ A;  1Z2W A;  4FBQ A;  4B2O A;  3C5W C;  3IVD A;  3D03 A;  1TCO A;  1IT6 A;  1T71 A;  4F0Z A;  1G5B A;  2A22 A;  4WWL A;  4V0V A;  1UTE A;  5F3W A;  4KKZ A;  1S3M A;  3QFO A;  3K7V C;  4TUG A;  3PSO A;  4O5G A;  5JJT A;  4H2I A;  2USH A;  2DXN A;  2GJU A;  3IVE A;  4V0W A;  3H68 A;  3THO B;  3H61 A;  5JPF A;  2WDF A;  3DW8 C;  3H66 A;  3H63 A;  3P71 C;  2WDC A;  2QJC A;  3PSN A;  5DNY A;  1NNW A;  2BDX A;  4OR9 A;  1KBP A;  5J28 A;  1MF8 A;  3QFK A;  1WAO 1;  2HYO A;  4O24 A;  3E7B A;  4Q7F A;  2DFJ A;  2YEQ A;  3E7A A;  1OI8 A;  2Q8U A;  4MP0 A;  3ZTV A;  3DSC A;  2WDE A;  1Z2X A;  4DSY A;  1QFC A;  4UT2 A;  3QFN A;  4TUI A;  2KKN A;  3LL8 A;  4MOY A;  2NYL C;  5INB A;  4NZV A;  1W24 A;  1UF3 A;  3RL3 A;  3H67 A;  2IAE C;  1SU1 A;  3H60 A;  3H64 A;  4ORB A;  2HY1 A;  1U32 A;  4JA9 A;  3V4Y A;  3DSD A;  5GTU A;  4H2G A;  4FBK A;  2ZBM A;  4FBW A;  5B8I A;  3C9F A;  1II7 A;  3ZU0 A;  4O4K A;  1USH A;  4ZX2 A;  2O8G A;  3GVE A;  4KBP A;  1S3N A;  2HYP A;  1JK7 A;  4I5L C;  2BQ8 X;  1HO5 A;  4IYP C;  1S95 A;  5JPE A;  2AHD A;  3IB7 A;  3KBP A;  1AUI A;  1OID A;  5IOH A;  3H69 A;  3T1I A;  4G9J A;  3HVQ A;  3AUZ A;  4LU9 A;  2R17 A;  3THN A;  1HPU A;  2Z06 A;  3FLO A;  3ICF A;  1XM7 A;  4DHL A;  3FGA C;  4H1S A;  2P6B A;  2NXF A;  4IL1 A;  4HD0 A;  4JA7 A;  1OIE A;  1QHW A;  4V0X A;  2Z72 A;  1S3L A;  3K7W C;  2ZO9 B;  4FCX A;  4I5N C;  3RL5 A;  3JYF A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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