3S1NL

Rna polymerase ii initiation complex with a 5-nt rna (variant 2)
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Initiation complex structure and promoter proofreading.
pubmed doi rcsb
molecule tags Transcription/rna/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 3
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 3s1nL00
4A3LL 2NVXL 4A3CL 2PMZP 4A3EL 3GTLL 2R7ZL 3HOVL 3S1NL 4C3IL 4AYBP 4A3BL 3GTML 4C2M1 2JA8L 3HOZL 2JA7L 2NVTL 3RZDL 4Y52L 3I4NL 1K83L 4A3ML 1TWAL 3GTPL 3S16L 2NVYL 3S14L 5M3FL 3S2HL 1I3QL 3S1QL 3HOYL 2WAQP 3HOWL 3S2DL 4A3JL 4BBRL 5C44L 5IP9L 4A3FL 3GTGL 5IYCL 5IYDL 3S17L 3RZOL 3S1ML 3S15L 3M3YL 1Y1VL 2NVQL 1WCML 1TWGL 2WB1P 1I50L 2JA6L 1SFOL 4BBSL 4BY7L 3HOXL 5C3EL 3GTKL 3K7AL 5M5XL 4C3HL 4BXXL 4A3GL 4A3DL 3GTOL 2JA5L 3GTQL 3HOUL 1TWCL 3HKZP 3GTJL 2Y0SP 3CQZL 2E2IL 2YU9L 4C3JL 1R9TL 3PO2L 5FLML 3H3VM 5C4JL 1TWHL 4QIWP 4A3KL 2B63L 2E2HL 1Y1WL 5C4XL 5M5YL 2VUML 4A93L 5IP7L 2R93L 4A3IL 5FJ8L 4Y7NL 3I4ML 5IYBL 3PO3L 4X6AL 4BY1L 5M5WL 3S1RL 3FKIL 2R92L 3M4OL 1TWFL 1I6HL 5M3ML 3H0GL 2E2JL
chains in the Genus database with same CATH superfamily
1FHMA 3GTLL 2V3BB 3P2AA 1NNQA 1H7VA 4A3BL 4ME3A 4GS7D 1B2OA 2KKDA 1BRFA 3B08B 3RZDL 3SS2A 3RZ6A 4Y52L 3NFPI 1TWAL 3KYWA 3S16L 5GAGc 2K2DA 2NVYL 1PFYA 5M3FL 1OWCA 4AR4A 1CADA 4LHLA 3WWNB 3S1QL 2L0ZA 2Z3RB 4AR5A 3S2DL 1LKMA 4A3FL 5EINC 2O5JD 3GTGL 2B5ID 3RZOL 1NXGA 3S1ML 3S15L 5GAHc 1I50L 3QVDA 5GAEc 3LPEB 3HAXC 2PYAA 4BY7L 1NXEA 5M5XL 2CKAA 3K35A 2A68D 3MQKB 4A3DL 3GTOL 1RB9A 4AI3A 3GTQL 3HOUL 1TWCL 5MFPA 3GTJL 2HR5A 1YV1A 2M6PA 4AI0A 4YWMA 4AR6A 4AR3A 3PO2L 1FHHA 1TWHL 4A3KL 4K9FA 3RZTA 4POGA 5C4XL 5M5YL 5DM71 2HVYC 1B2JA 1IROA 5FJ8L 4Y7NL 3HJYB 3PIP1 1SMMA 5MGNA 3M4OL 1YUZA 1TWFL 1BQ9A 1I6HL 3H0GL 2E2JL 5AN9H 1R0HA 2XJUA 4A3LL 2NVXL 3VPBE 4AHYA 1SMWA 8RXNA 4TVMA 3GTML 4JAFA 1P7PA 1LKOA 4C2M1 2JA8L 2AQCA 2H12A 1CAAA 3I4NL 1K83L 3KYUA 2Z3QB 2PVXA 1LTLA 3A44A 1C09A 4AI2A 5JVH1 1VZHA 1YK5A 5H1Sc 1PFUA 1SMUA 3KYYA 1YK4A 1F4LA 5C44L 5IP9L 3P8BA 1R0JA 2PSMC 2A69D 4LHNA 2NVQL 2V0FA 2JA6L 1T9OA 2EY4E 1BE7A 1RWDA 2M4VA 4BXXL 4AHWA 4A3GL 2GMGA 1BQ8A 2M6OA 4AHZA 1VCXA 2ZIXA 2QL0A 3HKZP 1JYBA 2VL6A 4AHXA 4E6YA 1E8JA 3CQZL 1RDGA 2PVEA 1OWBA 3LWRB 4C3JL 1R9TL 2XJRA 2RFKB 3PWFA 3PKIA 2XJPA 2B63L 1R0GA 2E2HL 5DM61 1Y1WL 2XJVA 2ERJA 2A6HD 2VUML 4A93L 5IP7L 1RYQA 1R0FA 5AI3A 3ZG6A 1IW7D 2M4YA 1T9QA 3H9BA 1S24A 5M5WL 3FDJA 2R92L 3MPSA 4JADA 2A6ED 2PMZP 2R7ZL 3HOVL 3S1NL 1VZIA 4C3IL 3H97A 1T9PA 2NYDA 1PFVA 2LCQA 3HOZL 2JA7L 4V196 2CR8A 4A3ML 1Z92B 3S2HL 5GADc 1QQTA 3HOYL 2XJQA 3WWLA 2WAQP 3HOWL 2PPTA 4A3JL 2RDVA 5MF6A 5MFZA 3LNLA 4TPUA 1IU5A 1PFWA 3J7Z1 1ODHA 4G6BA 4ZN1B 4XGHA 3QQCE 2JI1A 2AYJA 4JAEA 3PKJA 1SFOL 1WJVA 3K7AL 1RYTA 4C3HL 6RXNA 1RDVA 3PZAA 2JI3A 3LWVB 2BE5D 1DVBA 2Y0SP 3LWPB 5IY0A 1QYBA 3MSUA 5FLML 3H3VM 5C4JL 4RXNA 2KN9A 4B8CD 5MLC3 3J7Y1 4A3IL 3LWQB 3I4ML 1S2ZA 3B0AB 5K2ME 2C6AA 2DSXA 4BY1L 3S1RL 3LWOB 1PZXA 5RXNA 4A3CL 4A3EL 2C6BA 4AYBP 1QCVA 1YUXA 2NVTL 4WFN1 4UY81 3GTPL 3S14L 3KYVA 1IRNA 5EIOC 1I3QL 1IU6A 2JI2A 4BBRL 5IYCL 5IYDL 3S17L 2XJSA 3M3YL 1LKPA 1Y1VL 3JR7A 1WCML 1TWGL 2WB1P 3H99A 3HJWB 2ERSA 5JVG1 4BBSL 4POFA 3HOXL 5C3EL 3GTKL 4JAGA 1B71A 2APOB 2MS3A 2AUSB 3PL5A 2JA5L 2CKCA 7RXNA 4AI1A 2XJTA 3IU3I 2E2IL 2YU9L 4ZN3B 4XXBB 4QIWP 1R0IA 3H9CA 1BFYA 3KYXA 1S30A 2R93L 1DX8A 3PIO1 2V0EA 5IYBL 3PO3L 4X6AL 5AI2A 2J9UB 3FKIL 4YWLA 4U671 1ZRPA 1VZGA 3RYGA 5M3ML 1B13A
chains in the Genus database with same CATH topology
4A3LL 2NVXL 4A3CL 2PMZP 4A3EL 3GTLL 2R7ZL 3HOVL 3S1NL 4C3IL 4AYBP 4A3BL 3GTML 4C2M1 2JA8L 3HOZL 2JA7L 2NVTL 3RZDL 4Y52L 3I4NL 1K83L 4A3ML 1TWAL 3GTPL 3S16L 2NVYL 3S14L 5M3FL 3S2HL 1I3QL 3S1QL 3HOYL 2WAQP 3HOWL 3S2DL 4A3JL 4BBRL 5C44L 5IP9L 4A3FL 3GTGL 5IYCL 5IYDL 3S17L 3RZOL 3S1ML 3S15L 3M3YL 1Y1VL 2NVQL 1WCML 1TWGL 2WB1P 1I50L 2JA6L 1SFOL 4BBSL 4BY7L 3HOXL 5C3EL 3GTKL 3K7AL 5M5XL 4C3HL 4BXXL 4A3GL 4A3DL 3GTOL 2JA5L 3GTQL 3HOUL 1TWCL 3HKZP 3GTJL 2Y0SP 3CQZL 2E2IL 2YU9L 4C3JL 1R9TL 3PO2L 5FLML 3H3VM 5C4JL 1TWHL 4QIWP 4A3KL 2B63L 2E2HL 1Y1WL 5C4XL 5M5YL 2VUML 4A93L 5IP7L 2R93L 4A3IL 5FJ8L 4Y7NL 3I4ML 5IYBL 3PO3L 4X6AL 4BY1L 5M5WL 3S1RL 3FKIL 2R92L 3M4OL 1TWFL 1I6HL 5M3ML 3H0GL 2E2JL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3L L;  2NVX L;  4A3C L;  2PMZ P;  4A3E L;  3GTL L;  2R7Z L;  3HOV L;  3S1N L;  4C3I L;  4AYB P;  4A3B L;  3GTM L;  4C2M 1;  2JA8 L;  3HOZ L;  2JA7 L;  2NVT L;  3RZD L;  4Y52 L;  3I4N L;  1K83 L;  4A3M L;  1TWA L;  3GTP L;  3S16 L;  2NVY L;  3S14 L;  5M3F L;  3S2H L;  1I3Q L;  3S1Q L;  3HOY L;  2WAQ P;  3HOW L;  3S2D L;  4A3J L;  4BBR L;  5C44 L;  5IP9 L;  4A3F L;  3GTG L;  5IYC L;  5IYD L;  3S17 L;  3RZO L;  3S1M L;  3S15 L;  3M3Y L;  1Y1V L;  2NVQ L;  1WCM L;  1TWG L;  2WB1 P;  1I50 L;  2JA6 L;  1SFO L;  4BBS L;  4BY7 L;  3HOX L;  5C3E L;  3GTK L;  3K7A L;  5M5X L;  4C3H L;  4BXX L;  4A3G L;  4A3D L;  3GTO L;  2JA5 L;  3GTQ L;  3HOU L;  1TWC L;  3HKZ P;  3GTJ L;  2Y0S P;  3CQZ L;  2E2I L;  2YU9 L;  4C3J L;  1R9T L;  3PO2 L;  5FLM L;  3H3V M;  5C4J L;  1TWH L;  4QIW P;  4A3K L;  2B63 L;  2E2H L;  1Y1W L;  5C4X L;  5M5Y L;  2VUM L;  4A93 L;  5IP7 L;  2R93 L;  4A3I L;  5FJ8 L;  4Y7N L;  3I4M L;  5IYB L;  3PO3 L;  4X6A L;  4BY1 L;  5M5W L;  3S1R L;  3FKI L;  2R92 L;  3M4O L;  1TWF L;  1I6H L;  5M3M L;  3H0G L;  2E2J L; 
#chains in the Genus database with same CATH topology
 1FHM A;  3GTL L;  2V3B B;  3P2A A;  1NNQ A;  1H7V A;  4A3B L;  4ME3 A;  4GS7 D;  1B2O A;  2KKD A;  1BRF A;  3B08 B;  3RZD L;  3SS2 A;  3RZ6 A;  4Y52 L;  3NFP I;  1TWA L;  3KYW A;  3S16 L;  5GAG c;  2K2D A;  2NVY L;  1PFY A;  5M3F L;  1OWC A;  4AR4 A;  1CAD A;  4LHL A;  3WWN B;  3S1Q L;  2L0Z A;  2Z3R B;  4AR5 A;  3S2D L;  1LKM A;  4A3F L;  5EIN C;  2O5J D;  3GTG L;  2B5I D;  3RZO L;  1NXG A;  3S1M L;  3S15 L;  5GAH c;  1I50 L;  3QVD A;  5GAE c;  3LPE B;  3HAX C;  2PYA A;  4BY7 L;  1NXE A;  5M5X L;  2CKA A;  3K35 A;  2A68 D;  3MQK B;  4A3D L;  3GTO L;  1RB9 A;  4AI3 A;  3GTQ L;  3HOU L;  1TWC L;  5MFP A;  3GTJ L;  2HR5 A;  1YV1 A;  2M6P A;  4AI0 A;  4YWM A;  4AR6 A;  4AR3 A;  3PO2 L;  1FHH A;  1TWH L;  4A3K L;  4K9F A;  3RZT A;  4POG A;  5C4X L;  5M5Y L;  5DM7 1;  2HVY C;  1B2J A;  1IRO A;  5FJ8 L;  4Y7N L;  3HJY B;  3PIP 1;  1SMM A;  5MGN A;  3M4O L;  1YUZ A;  1TWF L;  1BQ9 A;  1I6H L;  3H0G L;  2E2J L;  5AN9 H;  1R0H A;  2XJU A;  4A3L L;  2NVX L;  3VPB E;  4AHY A;  1SMW A;  8RXN A;  4TVM A;  3GTM L;  4JAF A;  1P7P A;  1LKO A;  4C2M 1;  2JA8 L;  2AQC A;  2H12 A;  1CAA A;  3I4N L;  1K83 L;  3KYU A;  2Z3Q B;  2PVX A;  1LTL A;  3A44 A;  1C09 A;  4AI2 A;  5JVH 1;  1VZH A;  1YK5 A;  5H1S c;  1PFU A;  1SMU A;  3KYY A;  1YK4 A;  1F4L A;  5C44 L;  5IP9 L;  3P8B A;  1R0J A;  2PSM C;  2A69 D;  4LHN A;  2NVQ L;  2V0F A;  2JA6 L;  1T9O A;  2EY4 E;  1BE7 A;  1RWD A;  2M4V A;  4BXX L;  4AHW A;  4A3G L;  2GMG A;  1BQ8 A;  2M6O A;  4AHZ A;  1VCX A;  2ZIX A;  2QL0 A;  3HKZ P;  1JYB A;  2VL6 A;  4AHX A;  4E6Y A;  1E8J A;  3CQZ L;  1RDG A;  2PVE A;  1OWB A;  3LWR B;  4C3J L;  1R9T L;  2XJR A;  2RFK B;  3PWF A;  3PKI A;  2XJP A;  2B63 L;  1R0G A;  2E2H L;  5DM6 1;  1Y1W L;  2XJV A;  2ERJ A;  2A6H D;  2VUM L;  4A93 L;  5IP7 L;  1RYQ A;  1R0F A;  5AI3 A;  3ZG6 A;  1IW7 D;  2M4Y A;  1T9Q A;  3H9B A;  1S24 A;  5M5W L;  3FDJ A;  2R92 L;  3MPS A;  4JAD A;  2A6E D;  2PMZ P;  2R7Z L;  3HOV L;  3S1N L;  1VZI A;  4C3I L;  3H97 A;  1T9P A;  2NYD A;  1PFV A;  2LCQ A;  3HOZ L;  2JA7 L;  4V19 6;  2CR8 A;  4A3M L;  1Z92 B;  3S2H L;  5GAD c;  1QQT A;  3HOY L;  2XJQ A;  3WWL A;  2WAQ P;  3HOW L;  2PPT A;  4A3J L;  2RDV A;  5MF6 A;  5MFZ A;  3LNL A;  4TPU A;  1IU5 A;  1PFW A;  3J7Z 1;  1ODH A;  4G6B A;  4ZN1 B;  4XGH A;  3QQC E;  2JI1 A;  2AYJ A;  4JAE A;  3PKJ A;  1SFO L;  1WJV A;  3K7A L;  1RYT A;  4C3H L;  6RXN A;  1RDV A;  3PZA A;  2JI3 A;  3LWV B;  2BE5 D;  1DVB A;  2Y0S P;  3LWP B;  5IY0 A;  1QYB A;  3MSU A;  5FLM L;  3H3V M;  5C4J L;  4RXN A;  2KN9 A;  4B8C D;  5MLC 3;  3J7Y 1;  4A3I L;  3LWQ B;  3I4M L;  1S2Z A;  3B0A B;  5K2M E;  2C6A A;  2DSX A;  4BY1 L;  3S1R L;  3LWO B;  1PZX A;  5RXN A;  4A3C L;  4A3E L;  2C6B A;  4AYB P;  1QCV A;  1YUX A;  2NVT L;  4WFN 1;  4UY8 1;  3GTP L;  3S14 L;  3KYV A;  1IRN A;  5EIO C;  1I3Q L;  1IU6 A;  2JI2 A;  4BBR L;  5IYC L;  5IYD L;  3S17 L;  2XJS A;  3M3Y L;  1LKP A;  1Y1V L;  3JR7 A;  1WCM L;  1TWG L;  2WB1 P;  3H99 A;  3HJW B;  2ERS A;  5JVG 1;  4BBS L;  4POF A;  3HOX L;  5C3E L;  3GTK L;  4JAG A;  1B71 A;  2APO B;  2MS3 A;  2AUS B;  3PL5 A;  2JA5 L;  2CKC A;  7RXN A;  4AI1 A;  2XJT A;  3IU3 I;  2E2I L;  2YU9 L;  4ZN3 B;  4XXB B;  4QIW P;  1R0I A;  3H9C A;  1BFY A;  3KYX A;  1S30 A;  2R93 L;  1DX8 A;  3PIO 1;  2V0E A;  5IYB L;  3PO3 L;  4X6A L;  5AI2 A;  2J9U B;  3FKI L;  4YWL A;  4U67 1;  1ZRP A;  1VZG A;  3RYG A;  5M3M L;  1B13 A; 
#chains in the Genus database with same CATH homology
 4A3L L;  2NVX L;  4A3C L;  2PMZ P;  4A3E L;  3GTL L;  2R7Z L;  3HOV L;  3S1N L;  4C3I L;  4AYB P;  4A3B L;  3GTM L;  4C2M 1;  2JA8 L;  3HOZ L;  2JA7 L;  2NVT L;  3RZD L;  4Y52 L;  3I4N L;  1K83 L;  4A3M L;  1TWA L;  3GTP L;  3S16 L;  2NVY L;  3S14 L;  5M3F L;  3S2H L;  1I3Q L;  3S1Q L;  3HOY L;  2WAQ P;  3HOW L;  3S2D L;  4A3J L;  4BBR L;  5C44 L;  5IP9 L;  4A3F L;  3GTG L;  5IYC L;  5IYD L;  3S17 L;  3RZO L;  3S1M L;  3S15 L;  3M3Y L;  1Y1V L;  2NVQ L;  1WCM L;  1TWG L;  2WB1 P;  1I50 L;  2JA6 L;  1SFO L;  4BBS L;  4BY7 L;  3HOX L;  5C3E L;  3GTK L;  3K7A L;  5M5X L;  4C3H L;  4BXX L;  4A3G L;  4A3D L;  3GTO L;  2JA5 L;  3GTQ L;  3HOU L;  1TWC L;  3HKZ P;  3GTJ L;  2Y0S P;  3CQZ L;  2E2I L;  2YU9 L;  4C3J L;  1R9T L;  3PO2 L;  5FLM L;  3H3V M;  5C4J L;  1TWH L;  4QIW P;  4A3K L;  2B63 L;  2E2H L;  1Y1W L;  5C4X L;  5M5Y L;  2VUM L;  4A93 L;  5IP7 L;  2R93 L;  4A3I L;  5FJ8 L;  4Y7N L;  3I4M L;  5IYB L;  3PO3 L;  4X6A L;  4BY1 L;  5M5W L;  3S1R L;  3FKI L;  2R92 L;  3M4O L;  1TWF L;  1I6H L;  5M3M L;  3H0G L;  2E2J L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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