3FGAC

Structural basis of pp2a and sgo interaction
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
308
structure length
303
Chain Sequence
DEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVNRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRTRRTPDYFL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and function of the PP2A-shugoshin interaction
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Mus musculus
molecule keywords Serine/threonine-protein phosphatase 2A 65 kDa regulatory su
total genus 99
structure length 303
sequence length 308
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2008-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3fgaC00
3H67A 4OR9A 3KBPA 4ORCA 2XMOA 2HYOA 3IB7A 4O43A 3E7BA 4UWQA 1M63A 2WDDA 3CK2A 2HYPA 3H68A 4TUGA 4H2IA 4ZVZA 4ORBA 4V0XA 2IAEC 4J6OA 4LTYA 3V4YA 1IT6A 3EGHA 4IL1A 4MOYA 3H61A 1S8EA 3HVQA 3DSCA 4LU9A 3H66A 1S3NA 2P6BA 1Z2WA 4JA9A 1OIEA 2BDXA 3AUZA 1S95A 3ZTVA 2YVTA 2BQ8X 1AUIA 3QFNA 2Z72A 1W24A 1S70A 1MF8A 4ORAA 4MP0A 2ZBMA 2IE3C 1OI8A 1T71A 5IOHA 3FGAC 1KBPA 5F3WA 2Z06A 1JK7A 2CV9A 3C9FA 3K7WC 4DHLA 4Q7FA 4UT3A 3DSDA 4H2FA 5GTUA 4I5NC 1SU1A 4H2BA 4MOVA 5INBA 2NYMC 3AV0A 1NNWA 4JA7A 3DW8C 5EQVA 3RL5A 4DT2A 1II7A 1WAO1 4O5GA 5JPFA 4WWLA 4M0VA 1USHA 2GJUA 2WDEA 2IE4C 5C1VA 1HO5A 4H1YP 2A22A 2DFJA 1T70A 4H1SA 3N5UA 3LL8A 3H60A 3QFKA 3THNA 1HPUA 4FBQA 2HY1A 1S3MA 4DSYA 1HP1A 1FJMA 3QG5C 4UT2A 2KKNA 5JJTA 3K7VC 4O4KA 1XM7A 3IVEA 4V0VA 1UTEA 5HPEA 2O8GA 5B8IA 4FBKA 4G9JA 2NXFA 4HD0A 4O24A 1Z2XA 2NPPC 3RL4A 3IVDA 2R17A 3EGGA 3QFMA 1TCOA 2QJCA 5JPEA 4F0ZA 3T1IA 5J28A 2AHDA 2NYLC 1QFCA 5DNYA 1V73A 3H63A 1UF3A 2QFRA 4H2GA 1OIDA 2QFPA 1U32A 3RL3A 2O8AA 1S3LA 4UT3B 3QFOA 4LACC 4IYPC 1QHWA 3H69A 3IB8A 3JYFA 3E7AA 4KBPA 2WDFA 3H64A 2BCDA 4ZX2A 4TUIA 3P71C 4NZVA 2JOGA 2Q8UA 3ICFA 4FCXA 1G5BA 3PSNA 4XPNA 4YKEA 3THOB 3GVEA 4I5LC 4V0WA 3RQZA 3TGHA 1WARA 2USHA 3H62B 3C5WC 1XZWA 3PSOA 2WDCA 4B2OA 3ZU0A 4FBWA 2Z1AA 4KKZA
chains in the Genus database with same CATH superfamily
3H67A 4OR9A 3KBPA 4ORCA 2XMOA 2HYOA 3IB7A 4O43A 3E7BA 2YEQA 4UWQA 1M63A 2WDDA 3CK2A 2HYPA 3H68A 4TUGA 4H2IA 3D03A 4ORBA 4ZVZA 4V0XA 2IAEC 4J6OA 4LTYA 3V4YA 1IT6A 3EGHA 4IL1A 4MOYA 3H61A 1S8EA 3HVQA 3DSCA 4LU9A 3H66A 1S3NA 2P6BA 1Z2WA 4JA9A 1OIEA 2BDXA 3AUZA 1S95A 3ZTVA 2YVTA 2BQ8X 1AUIA 3QFNA 2Z72A 1W24A 1S70A 1MF8A 4ORAA 4MP0A 2ZBMA 2IE3C 1OI8A 1T71A 5IOHA 3FGAC 1KBPA 5F3WA 2Z06A 1JK7A 2CV9A 3C9FA 3K7WC 4DHLA 4Q7FA 4UT3A 3DSDA 4H2FA 5GTUA 4I5NC 1SU1A 4H2BA 3E0JA 4MOVA 2NYMC 5INBA 3AV0A 1NNWA 4JA7A 3DW8C 5EQVA 3RL5A 4DT2A 1II7A 1WAO1 4O5GA 5JPFA 4WWLA 4M0VA 1USHA 2GJUA 2WDEA 2IE4C 5C1VA 1HO5A 4H1YP 2A22A 2DFJA 1T70A 4H1SA 3N5UA 3LL8A 2ZO9B 3H60A 3QFKA 3THNA 1HPUA 4FBQA 2HY1A 1S3MA 4DSYA 1HP1A 1FJMA 3QG5C 4UT2A 2KKNA 5JJTA 3K7VC 4O4KA 1XM7A 3IVEA 4V0VA 1UTEA 5HPEA 2O8GA 5B8IA 4FBKA 4G9JA 2DXNA 2NXFA 4HD0A 4O24A 1Z2XA 2NPPC 3RL4A 3IVDA 2R17A 3EGGA 3QFMA 1TCOA 2QJCA 5JPEA 4F0ZA 2DXLA 3T1IA 5J28A 2AHDA 2NYLC 1QFCA 5DNYA 1V73A 3H63A 1UF3A 2QFRA 3FLOA 4H2GA 1OIDA 2QFPA 1U32A 2ZOAA 2O8AA 3RL3A 1S3LA 4UT3B 3QFOA 4LACC 4IYPC 1QHWA 3H69A 3IB8A 3JYFA 3E7AA 4KBPA 2WDFA 3H64A 2BCDA 4ZX2A 4TUIA 3P71C 4NZVA 2JOGA 2Q8UA 3ICFA 4FCXA 1G5BA 3PSNA 4XPNA 4YKEA 3THOB 3GVEA 4I5LC 4V0WA 3RQZA 3TGHA 1WARA 2USHA 3H62B 3C5WC 1XZWA 3PSOA 2WDCA 4B2OA 3ZU0A 4FBWA 2Z1AA 4KKZA
chains in the Genus database with same CATH topology
3H67A 4OR9A 3KBPA 4ORCA 2XMOA 2HYOA 3IB7A 4O43A 3E7BA 2YEQA 4UWQA 1M63A 2WDDA 3CK2A 2HYPA 3H68A 4TUGA 4H2IA 3D03A 4ORBA 4ZVZA 4V0XA 2IAEC 4J6OA 4LTYA 3V4YA 1IT6A 3EGHA 4IL1A 4MOYA 3H61A 1S8EA 3HVQA 3DSCA 4LU9A 3H66A 1S3NA 2P6BA 1Z2WA 4JA9A 1OIEA 2BDXA 3AUZA 1S95A 3ZTVA 2YVTA 2BQ8X 1AUIA 3QFNA 2Z72A 1W24A 1S70A 1MF8A 4ORAA 4MP0A 2ZBMA 2IE3C 1OI8A 1T71A 5IOHA 3FGAC 1KBPA 5F3WA 2Z06A 1JK7A 2CV9A 3C9FA 3K7WC 4DHLA 4Q7FA 4UT3A 3DSDA 4H2FA 5GTUA 4I5NC 1SU1A 4H2BA 3E0JA 4MOVA 2NYMC 5INBA 3AV0A 1NNWA 4JA7A 3DW8C 5EQVA 3RL5A 4DT2A 1II7A 1WAO1 4O5GA 5JPFA 4WWLA 4M0VA 1USHA 2GJUA 2WDEA 2IE4C 5C1VA 1HO5A 4H1YP 2A22A 2DFJA 1T70A 4H1SA 3N5UA 3LL8A 2ZO9B 3H60A 3QFKA 3THNA 1HPUA 4FBQA 2HY1A 1S3MA 4DSYA 1HP1A 1FJMA 3QG5C 4UT2A 2KKNA 5JJTA 3K7VC 4O4KA 1XM7A 3IVEA 4V0VA 1UTEA 5HPEA 2O8GA 5B8IA 4FBKA 4G9JA 2DXNA 2NXFA 4HD0A 4O24A 1Z2XA 2NPPC 3RL4A 3IVDA 2R17A 3EGGA 3QFMA 1TCOA 2QJCA 5JPEA 4F0ZA 2DXLA 3T1IA 5J28A 2AHDA 2NYLC 1QFCA 5DNYA 1V73A 3H63A 1UF3A 2QFRA 3FLOA 4H2GA 1OIDA 2QFPA 1U32A 2ZOAA 2O8AA 3RL3A 1S3LA 4UT3B 3QFOA 4LACC 4IYPC 1QHWA 3H69A 3IB8A 3JYFA 3E7AA 4KBPA 2WDFA 3H64A 2BCDA 4ZX2A 4TUIA 3P71C 4NZVA 2JOGA 2Q8UA 3ICFA 4FCXA 1G5BA 3PSNA 4XPNA 4YKEA 3THOB 3GVEA 4I5LC 4V0WA 3RQZA 3TGHA 1WARA 2USHA 3H62B 3C5WC 1XZWA 3PSOA 2WDCA 4B2OA 3ZU0A 4FBWA 2Z1AA 4KKZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H67 A;  4OR9 A;  3KBP A;  4ORC A;  2XMO A;  2HYO A;  3IB7 A;  4O43 A;  3E7B A;  4UWQ A;  1M63 A;  2WDD A;  3CK2 A;  2HYP A;  3H68 A;  4TUG A;  4H2I A;  4ZVZ A;  4ORB A;  4V0X A;  2IAE C;  4J6O A;  4LTY A;  3V4Y A;  1IT6 A;  3EGH A;  4IL1 A;  4MOY A;  3H61 A;  1S8E A;  3HVQ A;  3DSC A;  4LU9 A;  3H66 A;  1S3N A;  2P6B A;  1Z2W A;  4JA9 A;  1OIE A;  2BDX A;  3AUZ A;  1S95 A;  3ZTV A;  2YVT A;  2BQ8 X;  1AUI A;  3QFN A;  2Z72 A;  1W24 A;  1S70 A;  1MF8 A;  4ORA A;  4MP0 A;  2ZBM A;  2IE3 C;  1OI8 A;  1T71 A;  5IOH A;  3FGA C;  1KBP A;  5F3W A;  2Z06 A;  1JK7 A;  2CV9 A;  3C9F A;  3K7W C;  4DHL A;  4Q7F A;  4UT3 A;  3DSD A;  4H2F A;  5GTU A;  4I5N C;  1SU1 A;  4H2B A;  4MOV A;  5INB A;  2NYM C;  3AV0 A;  1NNW A;  4JA7 A;  3DW8 C;  5EQV A;  3RL5 A;  4DT2 A;  1II7 A;  1WAO 1;  4O5G A;  5JPF A;  4WWL A;  4M0V A;  1USH A;  2GJU A;  2WDE A;  2IE4 C;  5C1V A;  1HO5 A;  4H1Y P;  2A22 A;  2DFJ A;  1T70 A;  4H1S A;  3N5U A;  3LL8 A;  3H60 A;  3QFK A;  3THN A;  1HPU A;  4FBQ A;  2HY1 A;  1S3M A;  4DSY A;  1HP1 A;  1FJM A;  3QG5 C;  4UT2 A;  2KKN A;  5JJT A;  3K7V C;  4O4K A;  1XM7 A;  3IVE A;  4V0V A;  1UTE A;  5HPE A;  2O8G A;  5B8I A;  4FBK A;  4G9J A;  2NXF A;  4HD0 A;  4O24 A;  1Z2X A;  2NPP C;  3RL4 A;  3IVD A;  2R17 A;  3EGG A;  3QFM A;  1TCO A;  2QJC A;  5JPE A;  4F0Z A;  3T1I A;  5J28 A;  2AHD A;  2NYL C;  1QFC A;  5DNY A;  1V73 A;  3H63 A;  1UF3 A;  2QFR A;  4H2G A;  1OID A;  2QFP A;  1U32 A;  3RL3 A;  2O8A A;  1S3L A;  4UT3 B;  3QFO A;  4LAC C;  4IYP C;  1QHW A;  3H69 A;  3IB8 A;  3JYF A;  3E7A A;  4KBP A;  2WDF A;  3H64 A;  2BCD A;  4ZX2 A;  4TUI A;  3P71 C;  4NZV A;  2JOG A;  2Q8U A;  3ICF A;  4FCX A;  1G5B A;  3PSN A;  4XPN A;  4YKE A;  3THO B;  3GVE A;  4I5L C;  4V0W A;  3RQZ A;  3TGH A;  1WAR A;  2USH A;  3H62 B;  3C5W C;  1XZW A;  3PSO A;  2WDC A;  4B2O A;  3ZU0 A;  4FBW A;  2Z1A A;  4KKZ A; 
#chains in the Genus database with same CATH topology
 3H67 A;  4OR9 A;  3KBP A;  4ORC A;  2XMO A;  2HYO A;  3IB7 A;  4O43 A;  3E7B A;  2YEQ A;  4UWQ A;  1M63 A;  2WDD A;  3CK2 A;  2HYP A;  3H68 A;  4TUG A;  4H2I A;  3D03 A;  4ORB A;  4ZVZ A;  4V0X A;  2IAE C;  4J6O A;  4LTY A;  3V4Y A;  1IT6 A;  3EGH A;  4IL1 A;  4MOY A;  3H61 A;  1S8E A;  3HVQ A;  3DSC A;  4LU9 A;  3H66 A;  1S3N A;  2P6B A;  1Z2W A;  4JA9 A;  1OIE A;  2BDX A;  3AUZ A;  1S95 A;  3ZTV A;  2YVT A;  2BQ8 X;  1AUI A;  3QFN A;  2Z72 A;  1W24 A;  1S70 A;  1MF8 A;  4ORA A;  4MP0 A;  2ZBM A;  2IE3 C;  1OI8 A;  1T71 A;  5IOH A;  3FGA C;  1KBP A;  5F3W A;  2Z06 A;  1JK7 A;  2CV9 A;  3C9F A;  3K7W C;  4DHL A;  4Q7F A;  4UT3 A;  3DSD A;  4H2F A;  5GTU A;  4I5N C;  1SU1 A;  4H2B A;  3E0J A;  4MOV A;  2NYM C;  5INB A;  3AV0 A;  1NNW A;  4JA7 A;  3DW8 C;  5EQV A;  3RL5 A;  4DT2 A;  1II7 A;  1WAO 1;  4O5G A;  5JPF A;  4WWL A;  4M0V A;  1USH A;  2GJU A;  2WDE A;  2IE4 C;  5C1V A;  1HO5 A;  4H1Y P;  2A22 A;  2DFJ A;  1T70 A;  4H1S A;  3N5U A;  3LL8 A;  2ZO9 B;  3H60 A;  3QFK A;  3THN A;  1HPU A;  4FBQ A;  2HY1 A;  1S3M A;  4DSY A;  1HP1 A;  1FJM A;  3QG5 C;  4UT2 A;  2KKN A;  5JJT A;  3K7V C;  4O4K A;  1XM7 A;  3IVE A;  4V0V A;  1UTE A;  5HPE A;  2O8G A;  5B8I A;  4FBK A;  4G9J A;  2DXN A;  2NXF A;  4HD0 A;  4O24 A;  1Z2X A;  2NPP C;  3RL4 A;  3IVD A;  2R17 A;  3EGG A;  3QFM A;  1TCO A;  2QJC A;  5JPE A;  4F0Z A;  2DXL A;  3T1I A;  5J28 A;  2AHD A;  2NYL C;  1QFC A;  5DNY A;  1V73 A;  3H63 A;  1UF3 A;  2QFR A;  3FLO A;  4H2G A;  1OID A;  2QFP A;  1U32 A;  2ZOA A;  2O8A A;  3RL3 A;  1S3L A;  4UT3 B;  3QFO A;  4LAC C;  4IYP C;  1QHW A;  3H69 A;  3IB8 A;  3JYF A;  3E7A A;  4KBP A;  2WDF A;  3H64 A;  2BCD A;  4ZX2 A;  4TUI A;  3P71 C;  4NZV A;  2JOG A;  2Q8U A;  3ICF A;  4FCX A;  1G5B A;  3PSN A;  4XPN A;  4YKE A;  3THO B;  3GVE A;  4I5L C;  4V0W A;  3RQZ A;  3TGH A;  1WAR A;  2USH A;  3H62 B;  3C5W C;  1XZW A;  3PSO A;  2WDC A;  4B2O A;  3ZU0 A;  4FBW A;  2Z1A A;  4KKZ A; 
#chains in the Genus database with same CATH homology
 3H67 A;  4OR9 A;  3KBP A;  4ORC A;  2XMO A;  2HYO A;  3IB7 A;  4O43 A;  3E7B A;  2YEQ A;  4UWQ A;  1M63 A;  2WDD A;  3CK2 A;  2HYP A;  3H68 A;  4TUG A;  4H2I A;  3D03 A;  4ORB A;  4ZVZ A;  4V0X A;  2IAE C;  4J6O A;  4LTY A;  3V4Y A;  1IT6 A;  3EGH A;  4IL1 A;  4MOY A;  3H61 A;  1S8E A;  3HVQ A;  3DSC A;  4LU9 A;  3H66 A;  1S3N A;  2P6B A;  1Z2W A;  4JA9 A;  1OIE A;  2BDX A;  3AUZ A;  1S95 A;  3ZTV A;  2YVT A;  2BQ8 X;  1AUI A;  3QFN A;  2Z72 A;  1W24 A;  1S70 A;  1MF8 A;  4ORA A;  4MP0 A;  2ZBM A;  2IE3 C;  1OI8 A;  1T71 A;  5IOH A;  3FGA C;  1KBP A;  5F3W A;  2Z06 A;  1JK7 A;  2CV9 A;  3C9F A;  3K7W C;  4DHL A;  4Q7F A;  4UT3 A;  3DSD A;  4H2F A;  5GTU A;  4I5N C;  1SU1 A;  4H2B A;  3E0J A;  4MOV A;  2NYM C;  5INB A;  3AV0 A;  1NNW A;  4JA7 A;  3DW8 C;  5EQV A;  3RL5 A;  4DT2 A;  1II7 A;  1WAO 1;  4O5G A;  5JPF A;  4WWL A;  4M0V A;  1USH A;  2GJU A;  2WDE A;  2IE4 C;  5C1V A;  1HO5 A;  4H1Y P;  2A22 A;  2DFJ A;  1T70 A;  4H1S A;  3N5U A;  3LL8 A;  2ZO9 B;  3H60 A;  3QFK A;  3THN A;  1HPU A;  4FBQ A;  2HY1 A;  1S3M A;  4DSY A;  1HP1 A;  1FJM A;  3QG5 C;  4UT2 A;  2KKN A;  5JJT A;  3K7V C;  4O4K A;  1XM7 A;  3IVE A;  4V0V A;  1UTE A;  5HPE A;  2O8G A;  5B8I A;  4FBK A;  4G9J A;  2DXN A;  2NXF A;  4HD0 A;  4O24 A;  1Z2X A;  2NPP C;  3RL4 A;  3IVD A;  2R17 A;  3EGG A;  3QFM A;  1TCO A;  2QJC A;  5JPE A;  4F0Z A;  2DXL A;  3T1I A;  5J28 A;  2AHD A;  2NYL C;  1QFC A;  5DNY A;  1V73 A;  3H63 A;  1UF3 A;  2QFR A;  3FLO A;  4H2G A;  1OID A;  2QFP A;  1U32 A;  2ZOA A;  2O8A A;  3RL3 A;  1S3L A;  4UT3 B;  3QFO A;  4LAC C;  4IYP C;  1QHW A;  3H69 A;  3IB8 A;  3JYF A;  3E7A A;  4KBP A;  2WDF A;  3H64 A;  2BCD A;  4ZX2 A;  4TUI A;  3P71 C;  4NZV A;  2JOG A;  2Q8U A;  3ICF A;  4FCX A;  1G5B A;  3PSN A;  4XPN A;  4YKE A;  3THO B;  3GVE A;  4I5L C;  4V0W A;  3RQZ A;  3TGH A;  1WAR A;  2USH A;  3H62 B;  3C5W C;  1XZW A;  3PSO A;  2WDC A;  4B2O A;  3ZU0 A;  4FBW A;  2Z1A A;  4KKZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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