3HOUL

Complete rna polymerase ii elongation complex i with a t-u mismatch
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
pubmed doi rcsb
molecule tags Transcription,transferase/dna/rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 2
structure length 46
sequence length 46
chains with identical sequence X
ec nomenclature
pdb deposition date 2009-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 3houL00
3GTQL 3I4ML 2VUML 3HOWL 3GTOL 2R92L 3GTJL 2JA7L 2R93L 2NVQL 3HOUL 1TWHL 4BBRL 1Y1VL 4BBSL 1TWGL 3HOVL 3S1QL 4X6AL 4A93L 3H0GL 1TWCL 2E2HL 4A3CL 3M3YL 4A3KL 5M5XL 2NVXL 3RZDL 3I4NL 1K83L 3S1ML 4A3GL 4A3DL 4C3HL 4A3LL 3HKZP 1R9TL 2E2IL 5IYDL 3GTLL 2WB1P 4QIWP 2NVTL 2R7ZL 5C4XL 4C2M1 4A3ML 5M3FL 4BY7L 3S15L 2B63L 3PO3L 2YU9L 3HOZL 5FLML 5C3EL 5FJ8L 3K7AL 3H3VM 1TWFL 5IP7L 3GTGL 3GTPL 3S17L 1I3QL 5M3ML 1I6HL 3HOXL 4BY1L 3S1NL 3GTML 4Y52L 1Y1WL 3S14L 3S16L 2JA6L 2JA8L 3CQZL 1TWAL 4A3BL 2JA5L 2WAQP 1I50L 3S2HL 5C44L 5M5YL 4BXXL 4AYBP 3HOYL 2NVYL 4A3EL 5IP9L 5C4JL 4C3JL 3GTKL 3M4OL 4A3FL 4C3IL 4A3IL 5IYCL 2Y0SP 3S1RL 3S2DL 3RZOL 1WCML 3FKIL 2E2JL 4Y7NL 5IYBL 5M5WL 4A3JL 3PO2L 1SFOL 2PMZP
chains in the Genus database with same CATH superfamily
3I4ML 1SMMA 3PIO1 4UY81 2NVQL 4BBRL 3RZ6A 2V0EA 1R0GA 3S1QL 4JADA 1LTLA 2E2HL 3M3YL 4ZN3B 5M5XL 3H9BA 7RXNA 1B71A 3PWFA 1PFYA 4LHLA 2QL0A 4U671 2XJPA 1NXGA 3QQCE 1QYBA 4A3DL 4A3LL 4TPUA 1PZXA 5IYDL 1S2ZA 2ZIXA 4QIWP 5C4XL 4C2M1 3MQKB 1BQ9A 5M3FL 4BY7L 3S15L 2B63L 2YU9L 5FLML 5JVG1 5GAGc 4POFA 4WFN1 1TWFL 5IP7L 2LCQA 2CR8A 1I3QL 5M3ML 1ODHA 4GS7D 3B0AB 4RXNA 4Y52L 1RDVA 2JI2A 4V196 2C6BA 2A6HD 3S14L 3MSUA 4AHWA 2JA6L 2JA8L 2L0ZA 2KKDA 2J9UB 4A3BL 2XJSA 4B8CD 2RDVA 5C44L 4YWLA 5M5YL 4AYBP 2AQCA 2ERSA 1PFUA 3GTKL 3H99A 3SS2A 4A3FL 4A3IL 1R0HA 2EY4E 2BE5D 2A6ED 2M4YA 4E6YA 2HVYC 1ZRPA 1WCML 3KYXA 5RXNA 3PKJA 3M4OL 3LWPB 2PMZP 2VUML 1R0IA 3LWVB 2A68D 2V0FA 1T9OA 3GTOL 3A44A 2PPTA 3KYYA 3GTJL 2JA7L 5AI3A 2M6OA 1Y1VL 2CKCA 2RFKB 4AHXA 1TWGL 3HOVL 4A93L 1BE7A 3H0GL 3IU3I 2JI1A 4TVMA 4JAFA 2NVXL 1E8JA 2B5ID 1FHHA 5MF6A 3LNLA 3PIP1 3S1ML 2K2DA 5EIOC 3QVDA 3HJYB 1FHMA 4C3HL 5IY0A 3B08B 1CAAA 2R7ZL 1QCVA 2M6PA 1VZIA 4AI1A 1T9QA 1P7PA 6RXNA 3GTGL 3GTPL 3LWOB 4XGHA 3S17L 1LKMA 2ERJA 3P8BA 1I6HL 2XJRA 3H97A 3S1NL 4AR6A 3GTML 1Y1WL 3RYGA 3S16L 2AUSB 3CQZL 5GAHc 1RDGA 4JAGA 4G6BA 4AI2A 3K35A 3S2HL 4AI3A 4BXXL 2CKAA 1YK5A 4JAEA 5C4JL 2HR5A 1DVBA 1JYBA 5K2ME 1PFWA 5IYCL 2Y0SP 1RYQA 3HAXC 3S1RL 1F4LA 3HJWB 2XJVA 1R0JA 2E2JL 4AR3A 4AR4A 3HOWL 3HOUL 1B2OA 1TWHL 5MFPA 1QQTA 2PVEA 1IROA 2XJQA 4A3CL 3WWNB 2NYDA 3NFPI 3I4NL 1LKOA 1K83L 2JI3A 4A3GL 1Z92B 3RZTA 2Z3RB 5DM71 3HKZP 3KYUA 5MLC3 3GTLL 2NVTL 1BQ8A 5MFZA 4A3ML 2MS3A 1YUXA 1BFYA 3PO3L 3JR7A 3K7AL 3H3VM 5EINC 1VZGA 4POGA 2AYJA 1SMWA 1IU6A 3LPEB 3HOXL 4BY1L 2VL6A 1WJVA 1TWAL 1VZHA 1DX8A 3J7Z1 1SMUA 4AHYA 5H1Sc 2JA5L 2WAQP 4AI0A 1I50L 2XJTA 4ME3A 3HOYL 4A3EL 1RYTA 5IP9L 2V3BB 5AI2A 1NXEA 4AR5A 3ZG6A 3S2DL 3RZOL 2A69D 4Y7NL 2PVXA 5M5WL 3MPSA 1PFVA 1SFOL 3PO2L 3GTQL 2H12A 1IRNA 5JVH1 1VCXA 5GAEc 2R92L 2R93L 5MGNA 5DM61 1CADA 4BBSL 1RB9A 4X6AL 3FDJA 1S24A 3KYVA 1TWCL 2APOB 4A3KL 3RZDL 1BRFA 1B13A 1R0FA 1S30A 2GMGA 1R9TL 2E2IL 2WB1P 3LWRB 2XJUA 1RWDA 2PSMC 1YUZA 4ZN1B 3HOZL 5C3EL 5FJ8L 1H7VA 1IU5A 3J7Y1 3H9CA 1NNQA 3KYWA 1LKPA 4LHNA 4YWMA 3LWQB 8RXNA 2M4VA 1T9PA 1B2JA 3PKIA 4K9FA 1OWBA 2PYAA 2DSXA 2NVYL 2C6AA 5GADc 4C3JL 2KN9A 1C09A 1YV1A 5AN9H 3P2AA 3PZAA 4C3IL 3WWLA 2O5JD 2Z3QB 3PL5A 4AHZA 3FKIL 4XXBB 1YK4A 1IW7D 5IYBL 1OWCA 4A3JL 3VPBE
chains in the Genus database with same CATH topology
3GTQL 3I4ML 2VUML 3HOWL 3GTOL 2R92L 3GTJL 2JA7L 2R93L 2NVQL 3HOUL 1TWHL 4BBRL 1Y1VL 4BBSL 1TWGL 3HOVL 3S1QL 4X6AL 4A93L 3H0GL 1TWCL 2E2HL 4A3CL 3M3YL 4A3KL 5M5XL 2NVXL 3RZDL 3I4NL 1K83L 3S1ML 4A3GL 4A3DL 4C3HL 4A3LL 3HKZP 1R9TL 2E2IL 5IYDL 3GTLL 2WB1P 4QIWP 2NVTL 2R7ZL 5C4XL 4C2M1 4A3ML 5M3FL 4BY7L 3S15L 2B63L 3PO3L 2YU9L 3HOZL 5FLML 5C3EL 5FJ8L 3K7AL 3H3VM 1TWFL 5IP7L 3GTGL 3GTPL 3S17L 1I3QL 5M3ML 1I6HL 3HOXL 4BY1L 3S1NL 3GTML 4Y52L 1Y1WL 3S14L 3S16L 2JA6L 2JA8L 3CQZL 1TWAL 4A3BL 2JA5L 2WAQP 1I50L 3S2HL 5C44L 5M5YL 4BXXL 4AYBP 3HOYL 2NVYL 4A3EL 5IP9L 5C4JL 4C3JL 3GTKL 3M4OL 4A3FL 4C3IL 4A3IL 5IYCL 2Y0SP 3S1RL 3S2DL 3RZOL 1WCML 3FKIL 2E2JL 4Y7NL 5IYBL 5M5WL 4A3JL 3PO2L 1SFOL 2PMZP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTQ L;  3I4M L;  2VUM L;  3HOW L;  3GTO L;  2R92 L;  3GTJ L;  2JA7 L;  2R93 L;  2NVQ L;  3HOU L;  1TWH L;  4BBR L;  1Y1V L;  4BBS L;  1TWG L;  3HOV L;  3S1Q L;  4X6A L;  4A93 L;  3H0G L;  1TWC L;  2E2H L;  4A3C L;  3M3Y L;  4A3K L;  5M5X L;  2NVX L;  3RZD L;  3I4N L;  1K83 L;  3S1M L;  4A3G L;  4A3D L;  4C3H L;  4A3L L;  3HKZ P;  1R9T L;  2E2I L;  5IYD L;  3GTL L;  2WB1 P;  4QIW P;  2NVT L;  2R7Z L;  5C4X L;  4C2M 1;  4A3M L;  5M3F L;  4BY7 L;  3S15 L;  2B63 L;  3PO3 L;  2YU9 L;  3HOZ L;  5FLM L;  5C3E L;  5FJ8 L;  3K7A L;  3H3V M;  1TWF L;  5IP7 L;  3GTG L;  3GTP L;  3S17 L;  1I3Q L;  5M3M L;  1I6H L;  3HOX L;  4BY1 L;  3S1N L;  3GTM L;  4Y52 L;  1Y1W L;  3S14 L;  3S16 L;  2JA6 L;  2JA8 L;  3CQZ L;  1TWA L;  4A3B L;  2JA5 L;  2WAQ P;  1I50 L;  3S2H L;  5C44 L;  5M5Y L;  4BXX L;  4AYB P;  3HOY L;  2NVY L;  4A3E L;  5IP9 L;  5C4J L;  4C3J L;  3GTK L;  3M4O L;  4A3F L;  4C3I L;  4A3I L;  5IYC L;  2Y0S P;  3S1R L;  3S2D L;  3RZO L;  1WCM L;  3FKI L;  2E2J L;  4Y7N L;  5IYB L;  5M5W L;  4A3J L;  3PO2 L;  1SFO L;  2PMZ P; 
#chains in the Genus database with same CATH topology
 3I4M L;  1SMM A;  3PIO 1;  4UY8 1;  2NVQ L;  4BBR L;  3RZ6 A;  2V0E A;  1R0G A;  3S1Q L;  4JAD A;  1LTL A;  2E2H L;  3M3Y L;  4ZN3 B;  5M5X L;  3H9B A;  7RXN A;  1B71 A;  3PWF A;  1PFY A;  4LHL A;  2QL0 A;  4U67 1;  2XJP A;  1NXG A;  3QQC E;  1QYB A;  4A3D L;  4A3L L;  4TPU A;  1PZX A;  5IYD L;  1S2Z A;  2ZIX A;  4QIW P;  5C4X L;  4C2M 1;  3MQK B;  1BQ9 A;  5M3F L;  4BY7 L;  3S15 L;  2B63 L;  2YU9 L;  5FLM L;  5JVG 1;  5GAG c;  4POF A;  4WFN 1;  1TWF L;  5IP7 L;  2LCQ A;  2CR8 A;  1I3Q L;  5M3M L;  1ODH A;  4GS7 D;  3B0A B;  4RXN A;  4Y52 L;  1RDV A;  2JI2 A;  4V19 6;  2C6B A;  2A6H D;  3S14 L;  3MSU A;  4AHW A;  2JA6 L;  2JA8 L;  2L0Z A;  2KKD A;  2J9U B;  4A3B L;  2XJS A;  4B8C D;  2RDV A;  5C44 L;  4YWL A;  5M5Y L;  4AYB P;  2AQC A;  2ERS A;  1PFU A;  3GTK L;  3H99 A;  3SS2 A;  4A3F L;  4A3I L;  1R0H A;  2EY4 E;  2BE5 D;  2A6E D;  2M4Y A;  4E6Y A;  2HVY C;  1ZRP A;  1WCM L;  3KYX A;  5RXN A;  3PKJ A;  3M4O L;  3LWP B;  2PMZ P;  2VUM L;  1R0I A;  3LWV B;  2A68 D;  2V0F A;  1T9O A;  3GTO L;  3A44 A;  2PPT A;  3KYY A;  3GTJ L;  2JA7 L;  5AI3 A;  2M6O A;  1Y1V L;  2CKC A;  2RFK B;  4AHX A;  1TWG L;  3HOV L;  4A93 L;  1BE7 A;  3H0G L;  3IU3 I;  2JI1 A;  4TVM A;  4JAF A;  2NVX L;  1E8J A;  2B5I D;  1FHH A;  5MF6 A;  3LNL A;  3PIP 1;  3S1M L;  2K2D A;  5EIO C;  3QVD A;  3HJY B;  1FHM A;  4C3H L;  5IY0 A;  3B08 B;  1CAA A;  2R7Z L;  1QCV A;  2M6P A;  1VZI A;  4AI1 A;  1T9Q A;  1P7P A;  6RXN A;  3GTG L;  3GTP L;  3LWO B;  4XGH A;  3S17 L;  1LKM A;  2ERJ A;  3P8B A;  1I6H L;  2XJR A;  3H97 A;  3S1N L;  4AR6 A;  3GTM L;  1Y1W L;  3RYG A;  3S16 L;  2AUS B;  3CQZ L;  5GAH c;  1RDG A;  4JAG A;  4G6B A;  4AI2 A;  3K35 A;  3S2H L;  4AI3 A;  4BXX L;  2CKA A;  1YK5 A;  4JAE A;  5C4J L;  2HR5 A;  1DVB A;  1JYB A;  5K2M E;  1PFW A;  5IYC L;  2Y0S P;  1RYQ A;  3HAX C;  3S1R L;  1F4L A;  3HJW B;  2XJV A;  1R0J A;  2E2J L;  4AR3 A;  4AR4 A;  3HOW L;  3HOU L;  1B2O A;  1TWH L;  5MFP A;  1QQT A;  2PVE A;  1IRO A;  2XJQ A;  4A3C L;  3WWN B;  2NYD A;  3NFP I;  3I4N L;  1LKO A;  1K83 L;  2JI3 A;  4A3G L;  1Z92 B;  3RZT A;  2Z3R B;  5DM7 1;  3HKZ P;  3KYU A;  5MLC 3;  3GTL L;  2NVT L;  1BQ8 A;  5MFZ A;  4A3M L;  2MS3 A;  1YUX A;  1BFY A;  3PO3 L;  3JR7 A;  3K7A L;  3H3V M;  5EIN C;  1VZG A;  4POG A;  2AYJ A;  1SMW A;  1IU6 A;  3LPE B;  3HOX L;  4BY1 L;  2VL6 A;  1WJV A;  1TWA L;  1VZH A;  1DX8 A;  3J7Z 1;  1SMU A;  4AHY A;  5H1S c;  2JA5 L;  2WAQ P;  4AI0 A;  1I50 L;  2XJT A;  4ME3 A;  3HOY L;  4A3E L;  1RYT A;  5IP9 L;  2V3B B;  5AI2 A;  1NXE A;  4AR5 A;  3ZG6 A;  3S2D L;  3RZO L;  2A69 D;  4Y7N L;  2PVX A;  5M5W L;  3MPS A;  1PFV A;  1SFO L;  3PO2 L;  3GTQ L;  2H12 A;  1IRN A;  5JVH 1;  1VCX A;  5GAE c;  2R92 L;  2R93 L;  5MGN A;  5DM6 1;  1CAD A;  4BBS L;  1RB9 A;  4X6A L;  3FDJ A;  1S24 A;  3KYV A;  1TWC L;  2APO B;  4A3K L;  3RZD L;  1BRF A;  1B13 A;  1R0F A;  1S30 A;  2GMG A;  1R9T L;  2E2I L;  2WB1 P;  3LWR B;  2XJU A;  1RWD A;  2PSM C;  1YUZ A;  4ZN1 B;  3HOZ L;  5C3E L;  5FJ8 L;  1H7V A;  1IU5 A;  3J7Y 1;  3H9C A;  1NNQ A;  3KYW A;  1LKP A;  4LHN A;  4YWM A;  3LWQ B;  8RXN A;  2M4V A;  1T9P A;  1B2J A;  3PKI A;  4K9F A;  1OWB A;  2PYA A;  2DSX A;  2NVY L;  2C6A A;  5GAD c;  4C3J L;  2KN9 A;  1C09 A;  1YV1 A;  5AN9 H;  3P2A A;  3PZA A;  4C3I L;  3WWL A;  2O5J D;  2Z3Q B;  3PL5 A;  4AHZ A;  3FKI L;  4XXB B;  1YK4 A;  1IW7 D;  5IYB L;  1OWC A;  4A3J L;  3VPB E; 
#chains in the Genus database with same CATH homology
 3GTQ L;  3I4M L;  2VUM L;  3HOW L;  3GTO L;  2R92 L;  3GTJ L;  2JA7 L;  2R93 L;  2NVQ L;  3HOU L;  1TWH L;  4BBR L;  1Y1V L;  4BBS L;  1TWG L;  3HOV L;  3S1Q L;  4X6A L;  4A93 L;  3H0G L;  1TWC L;  2E2H L;  4A3C L;  3M3Y L;  4A3K L;  5M5X L;  2NVX L;  3RZD L;  3I4N L;  1K83 L;  3S1M L;  4A3G L;  4A3D L;  4C3H L;  4A3L L;  3HKZ P;  1R9T L;  2E2I L;  5IYD L;  3GTL L;  2WB1 P;  4QIW P;  2NVT L;  2R7Z L;  5C4X L;  4C2M 1;  4A3M L;  5M3F L;  4BY7 L;  3S15 L;  2B63 L;  3PO3 L;  2YU9 L;  3HOZ L;  5FLM L;  5C3E L;  5FJ8 L;  3K7A L;  3H3V M;  1TWF L;  5IP7 L;  3GTG L;  3GTP L;  3S17 L;  1I3Q L;  5M3M L;  1I6H L;  3HOX L;  4BY1 L;  3S1N L;  3GTM L;  4Y52 L;  1Y1W L;  3S14 L;  3S16 L;  2JA6 L;  2JA8 L;  3CQZ L;  1TWA L;  4A3B L;  2JA5 L;  2WAQ P;  1I50 L;  3S2H L;  5C44 L;  5M5Y L;  4BXX L;  4AYB P;  3HOY L;  2NVY L;  4A3E L;  5IP9 L;  5C4J L;  4C3J L;  3GTK L;  3M4O L;  4A3F L;  4C3I L;  4A3I L;  5IYC L;  2Y0S P;  3S1R L;  3S2D L;  3RZO L;  1WCM L;  3FKI L;  2E2J L;  4Y7N L;  5IYB L;  5M5W L;  4A3J L;  3PO2 L;  1SFO L;  2PMZ P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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