3LWQB

Structure of h/aca rnp bound to a substrate rna containing 3mu
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
51
structure length
51
Chain Sequence
RIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase .
pubmed doi rcsb
molecule tags Isomerase/rna binding protein/rna
source organism Pyrococcus furiosus
molecule keywords Pseudouridine synthase Cbf5
total genus 5
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 2010-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04135 Nop10p Nucleolar RNA-binding protein, Nop10p family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.40 Mainly Beta Single Sheet Rubrerythrin, domain 2 H/ACA ribonucleoprotein complex, subunit Nop10 3lwqB00
3HJYB 3LWPB 3HAXC 3HJWB 3LWQB 2AQCA 3LWRB 3MQKB 2HVYC 2EY4E 2APOB 3LWVB 2AUSB 3LWOB 2RFKB
chains in the Genus database with same CATH superfamily
2E2HL 1S24A 5IP9L 4AI2A 3H9BA 3LPEB 3HJYB 1TWHL 5C4JL 2ERJA 1NXEA 4A3EL 4XGHA 1RYQA 3PWFA 2EY4E 4ME3A 4V196 3HOZL 4YWMA 2NVQL 2XJVA 2QL0A 3HOXL 2A69D 1Z92B 3GTML 3K35A 5IYCL 2VL6A 5GADc 1YV1A 5IP7L 2JA7L 4JAFA 1WJVA 4JAEA 4C2M1 4A3GL 3RZDL 1FHHA 2C6AA 2B5ID 4LHNA 2ZIXA 2R93L 2E2IL 1YK4A 3CQZL 1SMWA 2HR5A 1BE7A 1NXGA 1B2OA 4U671 4AR4A 3FKIL 4BBRL 2JI3A 4A3DL 3KYVA 1LKPA 2XJUA 3GTPL 1LKOA 4AR3A 4TVMA 1PFWA 1I6HL 5GAEc 1DX8A 2V3BB 2M6OA 2BE5D 4G6BA 3KYYA 1S2ZA 5K2ME 1BFYA 1JYBA 3PKJA 2CKAA 1CAAA 2E2JL 1BQ9A 1WCML 4BY1L 2A6ED 5JVH1 2M4VA 3LWQB 3JR7A 1R9TL 4WFN1 3GTOL 4C3HL 5AN9H 1NNQA 1R0HA 4A3LL 4A3BL 4C3IL 1R0GA 1B71A 1VZIA 2K2DA 5M5XL 1QCVA 4BY7L 3FDJA 3PZAA 4C3JL 5JVG1 3S1NL 5MFPA 2CKCA 1YUXA 3I4NL 2APOB 1BRFA 1ZRPA 3PO2L 2XJTA 4POFA 3M3YL 2JI1A 1Y1VL 5GAGc 3RYGA 5AI3A 2JA6L 3HOVL 3P2AA 3H9CA 3GTLL 4AHZA 2Z3RB 3NFPI 2KKDA 5MGNA 4A3CL 3SS2A 3PIP1 2KN9A 2B63L 2NVXL 5EIOC 2M6PA 2CR8A 5RXNA 2MS3A 3K7AL 1OWBA 1T9PA 2O5JD 5DM71 1H7VA 2V0FA 1CADA 1IW7D 1T9OA 1E8JA 1RWDA 2GMGA 1Y1WL 3PIO1 5MLC3 5M5WL 3QQCE 2JI2A 3RZ6A 3WWNB 1LTLA 4LHLA 2Y0SP 4K9FA 1BQ8A 3LWVB 2AUSB 3S15L 3HOUL 1IU5A 1RDVA 2PVXA 2WAQP 4JADA 3GTKL 4A93L 5GAHc 2NYDA 1I3QL 1VCXA 3RZTA 5M3ML 4Y52L 4AI0A 5H1Sc 2RDVA 3H97A 2DSXA 1QQTA 1VZGA 4AR5A 3S2HL 2A68D 2YU9L 3HJWB 1R0IA 4ZN1B 5M3FL 3H99A 2ERSA 1T9QA 1P7PA 5C3EL 4AI1A 4A3KL 1IROA 5MF6A 5IYDL 2R7ZL 1RDGA 3KYUA 2RFKB 3A44A 8RXNA 1IU6A 3QVDA 1SMUA 2LCQA 2AYJA 1FHMA 2XJRA 1IRNA 2R92L 1K83L 2JA5L 3P8BA 4A3JL 2XJSA 4GS7D 2L0ZA 1PFYA 3KYXA 5FJ8L 4A3FL 5FLML 2VUML 7RXNA 3IU3I 3ZG6A 2HVYC 5C4XL 3S14L 2PYAA 1DVBA 2A6HD 2XJPA 3S1RL 3S1ML 1R0JA 1PZXA 1RYTA 4POGA 3HAXC 3HKZP 5C44L 3S16L 5IYBL 2PVEA 4AHWA 5DM61 5EINC 3H3VM 1F4LA 1SMMA 3LWRB 3MPSA 2NVTL 1C09A 2PMZP 4BXXL 3M4OL 1S30A 3GTJL 3J7Z1 3B08B 1PFVA 3MSUA 3LWPB 4AHXA 1YK5A 1R0FA 1TWCL 4X6AL 2C6BA 4AHYA 4B8CD 1B2JA 4AYBP 1RB9A 2V0EA 3GTQL 3I4ML 4AR6A 2AQCA 4QIWP 3LWOB 5M5YL 4Y7NL 4XXBB 4RXNA 5IY0A 4BBSL 1ODHA 4ZN3B 3PKIA 3HOWL 3KYWA 1B13A 5MFZA 2XJQA 3WWLA 4AI3A 2PPTA 5AI2A 2NVYL 3H0GL 3LNLA 1I50L 4YWLA 3HOYL 1VZHA 4TPUA 2Z3QB 1SFOL 2H12A 3S1QL 3VPBE 4JAGA 2WB1P 3J7Y1 3PL5A 3RZOL 1TWFL 1PFUA 2J9UB 4A3ML 1LKMA 3B0AB 3PO3L 1OWCA 1YUZA 3S2DL 4UY81 1TWAL 3MQKB 3GTGL 2M4YA 1QYBA 3S17L 4E6YA 2PSMC 1TWGL 2JA8L 4A3IL 6RXNA
chains in the Genus database with same CATH topology
3HJYB 3LWPB 3HAXC 3HJWB 3LWQB 2AQCA 3LWRB 3MQKB 2HVYC 2EY4E 2APOB 3LWVB 2AUSB 3LWOB 2RFKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HJY B;  3LWP B;  3HAX C;  3HJW B;  3LWQ B;  2AQC A;  3LWR B;  3MQK B;  2HVY C;  2EY4 E;  2APO B;  3LWV B;  2AUS B;  3LWO B;  2RFK B; 
#chains in the Genus database with same CATH topology
 2E2H L;  1S24 A;  5IP9 L;  4AI2 A;  3H9B A;  3LPE B;  3HJY B;  1TWH L;  5C4J L;  2ERJ A;  1NXE A;  4A3E L;  4XGH A;  1RYQ A;  3PWF A;  2EY4 E;  4ME3 A;  4V19 6;  3HOZ L;  4YWM A;  2NVQ L;  2XJV A;  2QL0 A;  3HOX L;  2A69 D;  1Z92 B;  3GTM L;  3K35 A;  5IYC L;  2VL6 A;  5GAD c;  1YV1 A;  5IP7 L;  2JA7 L;  4JAF A;  1WJV A;  4JAE A;  4C2M 1;  4A3G L;  3RZD L;  1FHH A;  2C6A A;  2B5I D;  4LHN A;  2ZIX A;  2R93 L;  2E2I L;  1YK4 A;  3CQZ L;  1SMW A;  2HR5 A;  1BE7 A;  1NXG A;  1B2O A;  4U67 1;  4AR4 A;  3FKI L;  4BBR L;  2JI3 A;  4A3D L;  3KYV A;  1LKP A;  2XJU A;  3GTP L;  1LKO A;  4AR3 A;  4TVM A;  1PFW A;  1I6H L;  5GAE c;  1DX8 A;  2V3B B;  2M6O A;  2BE5 D;  4G6B A;  3KYY A;  1S2Z A;  5K2M E;  1BFY A;  1JYB A;  3PKJ A;  2CKA A;  1CAA A;  2E2J L;  1BQ9 A;  1WCM L;  4BY1 L;  2A6E D;  5JVH 1;  2M4V A;  3LWQ B;  3JR7 A;  1R9T L;  4WFN 1;  3GTO L;  4C3H L;  5AN9 H;  1NNQ A;  1R0H A;  4A3L L;  4A3B L;  4C3I L;  1R0G A;  1B71 A;  1VZI A;  2K2D A;  5M5X L;  1QCV A;  4BY7 L;  3FDJ A;  3PZA A;  4C3J L;  5JVG 1;  3S1N L;  5MFP A;  2CKC A;  1YUX A;  3I4N L;  2APO B;  1BRF A;  1ZRP A;  3PO2 L;  2XJT A;  4POF A;  3M3Y L;  2JI1 A;  1Y1V L;  5GAG c;  3RYG A;  5AI3 A;  2JA6 L;  3HOV L;  3P2A A;  3H9C A;  3GTL L;  4AHZ A;  2Z3R B;  3NFP I;  2KKD A;  5MGN A;  4A3C L;  3SS2 A;  3PIP 1;  2KN9 A;  2B63 L;  2NVX L;  5EIO C;  2M6P A;  2CR8 A;  5RXN A;  2MS3 A;  3K7A L;  1OWB A;  1T9P A;  2O5J D;  5DM7 1;  1H7V A;  2V0F A;  1CAD A;  1IW7 D;  1T9O A;  1E8J A;  1RWD A;  2GMG A;  1Y1W L;  3PIO 1;  5MLC 3;  5M5W L;  3QQC E;  2JI2 A;  3RZ6 A;  3WWN B;  1LTL A;  4LHL A;  2Y0S P;  4K9F A;  1BQ8 A;  3LWV B;  2AUS B;  3S15 L;  3HOU L;  1IU5 A;  1RDV A;  2PVX A;  2WAQ P;  4JAD A;  3GTK L;  4A93 L;  5GAH c;  2NYD A;  1I3Q L;  1VCX A;  3RZT A;  5M3M L;  4Y52 L;  4AI0 A;  5H1S c;  2RDV A;  3H97 A;  2DSX A;  1QQT A;  1VZG A;  4AR5 A;  3S2H L;  2A68 D;  2YU9 L;  3HJW B;  1R0I A;  4ZN1 B;  5M3F L;  3H99 A;  2ERS A;  1T9Q A;  1P7P A;  5C3E L;  4AI1 A;  4A3K L;  1IRO A;  5MF6 A;  5IYD L;  2R7Z L;  1RDG A;  3KYU A;  2RFK B;  3A44 A;  8RXN A;  1IU6 A;  3QVD A;  1SMU A;  2LCQ A;  2AYJ A;  1FHM A;  2XJR A;  1IRN A;  2R92 L;  1K83 L;  2JA5 L;  3P8B A;  4A3J L;  2XJS A;  4GS7 D;  2L0Z A;  1PFY A;  3KYX A;  5FJ8 L;  4A3F L;  5FLM L;  2VUM L;  7RXN A;  3IU3 I;  3ZG6 A;  2HVY C;  5C4X L;  3S14 L;  2PYA A;  1DVB A;  2A6H D;  2XJP A;  3S1R L;  3S1M L;  1R0J A;  1PZX A;  1RYT A;  4POG A;  3HAX C;  3HKZ P;  5C44 L;  3S16 L;  5IYB L;  2PVE A;  4AHW A;  5DM6 1;  5EIN C;  3H3V M;  1F4L A;  1SMM A;  3LWR B;  3MPS A;  2NVT L;  1C09 A;  2PMZ P;  4BXX L;  3M4O L;  1S30 A;  3GTJ L;  3J7Z 1;  3B08 B;  1PFV A;  3MSU A;  3LWP B;  4AHX A;  1YK5 A;  1R0F A;  1TWC L;  4X6A L;  2C6B A;  4AHY A;  4B8C D;  1B2J A;  4AYB P;  1RB9 A;  2V0E A;  3GTQ L;  3I4M L;  4AR6 A;  2AQC A;  4QIW P;  3LWO B;  5M5Y L;  4Y7N L;  4XXB B;  4RXN A;  5IY0 A;  4BBS L;  1ODH A;  4ZN3 B;  3PKI A;  3HOW L;  3KYW A;  1B13 A;  5MFZ A;  2XJQ A;  3WWL A;  4AI3 A;  2PPT A;  5AI2 A;  2NVY L;  3H0G L;  3LNL A;  1I50 L;  4YWL A;  3HOY L;  1VZH A;  4TPU A;  2Z3Q B;  1SFO L;  2H12 A;  3S1Q L;  3VPB E;  4JAG A;  2WB1 P;  3J7Y 1;  3PL5 A;  3RZO L;  1TWF L;  1PFU A;  2J9U B;  4A3M L;  1LKM A;  3B0A B;  3PO3 L;  1OWC A;  1YUZ A;  3S2D L;  4UY8 1;  1TWA L;  3MQK B;  3GTG L;  2M4Y A;  1QYB A;  3S17 L;  4E6Y A;  2PSM C;  1TWG L;  2JA8 L;  4A3I L;  6RXN A; 
#chains in the Genus database with same CATH homology
 3HJY B;  3LWP B;  3HAX C;  3HJW B;  3LWQ B;  2AQC A;  3LWR B;  3MQK B;  2HVY C;  2EY4 E;  2APO B;  3LWV B;  2AUS B;  3LWO B;  2RFK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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