3LWRB

Structure of h/aca rnp bound to a substrate rna containing 4su
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
53
structure length
53
Chain Sequence
FRIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLGI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase .
pubmed doi rcsb
molecule tags Isomerase/rna binding protein/rna
source organism Pyrococcus furiosus
molecule keywords Pseudouridine synthase Cbf5
total genus 8
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2010-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04135 Nop10p Nucleolar RNA-binding protein, Nop10p family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.40 Mainly Beta Single Sheet Rubrerythrin, domain 2 H/ACA ribonucleoprotein complex, subunit Nop10 3lwrB00
2AUSB 2HVYC 3LWPB 3MQKB 2RFKB 3LWVB 2EY4E 3HJWB 3LWRB 3LWQB 3HJYB 2APOB 3HAXC 3LWOB 2AQCA
chains in the Genus database with same CATH superfamily
4G6BA 1NNQA 1R0GA 1FHMA 3PKIA 1LKOA 1WCML 2XJSA 3LNLA 2Z3QB 1TWFL 3S1ML 2JA8L 3PWFA 2M6PA 2VL6A 5AI2A 3LWPB 4YWLA 4X6AL 3B0AB 2PVEA 5M5XL 4RXNA 3I4NL 3HOXL 4C3JL 1B2OA 1IW7D 4AHWA 4BY1L 4BBSL 3RYGA 2XJUA 1T9QA 3A44A 2H12A 5AN9H 1R0HA 2PVXA 5MFZA 2E2IL 1P7PA 4AR3A 4TVMA 5C4JL 1SFOL 3GTOL 2A68D 4XGHA 3LWOB 4AI1A 2CR8A 4A3FL 4BXXL 7RXNA 1TWGL 1TWHL 2ERJA 5AI3A 3J7Y1 2A6HD 3S15L 1SMUA 2JA5L 2NYDA 4ME3A 1B71A 1CADA 2NVYL 2XJQA 2E2JL 4AHYA 1YUZA 3GTKL 3KYUA 4AR5A 5MF6A 1S2ZA 3P2AA 2B63L 1YK5A 3P8BA 5JVG1 1B2JA 5GAHc 3MQKB 1S24A 1K83L 2EY4E 3CQZL 2WAQP 2A6ED 5GAGc 5MGNA 2E2HL 3IU3I 5IYBL 3WWNB 1OWCA 4A3BL 1DVBA 3H9BA 4E6YA 2HVYC 1S30A 4A3EL 1PFVA 3HOVL 1IRNA 1VZIA 1C09A 1VCXA 1F4LA 1LKMA 2JI1A 2XJTA 3S17L 3HOWL 3S1NL 1DX8A 3M3YL 5DM61 5C44L 1PFYA 3S1RL 4GS7D 2GMGA 5GADc 2PYAA 4JAFA 2CKAA 3KYWA 3SS2A 4A3LL 4LHNA 5EIOC 1NXGA 3LWRB 5C3EL 5M5YL 2JA6L 4V196 2LCQA 2HR5A 1I3QL 1JYBA 4Y7NL 2CKCA 1B13A 3S14L 3H0GL 3HJYB 2ERSA 3KYVA 5FLML 1RYTA 4JAGA 3LPEB 4BBRL 2PPTA 2ZIXA 2QL0A 2M6OA 4JADA 4AI2A 4WFN1 3PL5A 1I50L 2KKDA 2XJRA 1PFWA 5M3FL 4A3KL 4Y52L 5JVH1 3S1QL 4A3ML 3KYXA 1PFUA 2JA7L 3HJWB 3S2HL 3S2DL 2APOB 4BY7L 3NFPI 2PMZP 3RZTA 1BE7A 5IP7L 3HKZP 1R0JA 4QIWP 4POFA 3H97A 1R0FA 2V0FA 2L0ZA 4XXBB 5IY0A 1BQ9A 3HOZL 1H7VA 3JR7A 5RXNA 2WB1P 2R7ZL 1Y1WL 3FDJA 1IROA 3PO3L 2AQCA 4B8CD 4LHLA 3FKIL 1T9OA 3J7Z1 2V0EA 1T9PA 1YK4A 5IYCL 3GTLL 1CAAA 4AHXA 2R93L 3GTQL 1NXEA 4C3HL 3LWQB 1RDVA 4A3DL 2NVQL 1LTLA 3ZG6A 1TWCL 5H1Sc 3K35A 3QQCE 1SMWA 1R0IA 1RDGA 2M4VA 1R9TL 3GTGL 1QYBA 2KN9A 5GAEc 4U671 4A3GL 2XJVA 2A69D 3KYYA 2JI3A 1QCVA 1OWBA 2J9UB 4TPUA 1Y1VL 1IU6A 2C6BA 5C4XL 3PIP1 4AYBP 5FJ8L 4C2M1 4A3CL 2MS3A 3PO2L 4A3JL 2R92L 4A3IL 2Z3RB 4AI3A 3PZAA 3WWLA 3GTPL 1LKPA 2C6AA 1BFYA 3H99A 5DM71 1YV1A 3PIO1 5IYDL 3GTML 1TWAL 2BE5D 2Y0SP 2YU9L 3RZDL 1QQTA 3MSUA 1RWDA 4C3IL 3VPBE 2JI2A 2AUSB 1YUXA 3MPSA 6RXNA 5IP9L 2M4YA 3LWVB 5M3ML 4ZN3B 1BQ8A 4AHZA 4K9FA 1IU5A 1E8JA 5EINC 3HOUL 1WJVA 1VZGA 1Z92B 4AR6A 3K7AL 3RZ6A 4POGA 2V3BB 3B08B 1I6HL 3HAXC 4UY81 2RFKB 4AR4A 2B5ID 5K2ME 1RB9A 2XJPA 3I4ML 4AI0A 5MFPA 2O5JD 1RYQA 3M4OL 1BRFA 1SMMA 5M5WL 1VZHA 2NVTL 4ZN1B 8RXNA 2DSXA 1FHHA 4YWMA 1ODHA 3PKJA 2RDVA 2K2DA 1PZXA 3QVDA 3H9CA 2NVXL 3GTJL 2AYJA 1ZRPA 5MLC3 3RZOL 4JAEA 3HOYL 2VUML 2PSMC 3S16L 3H3VM 4A93L
chains in the Genus database with same CATH topology
2AUSB 2HVYC 3LWPB 3MQKB 2RFKB 3LWVB 2EY4E 3HJWB 3LWRB 3LWQB 3HJYB 2APOB 3HAXC 3LWOB 2AQCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AUS B;  2HVY C;  3LWP B;  3MQK B;  2RFK B;  3LWV B;  2EY4 E;  3HJW B;  3LWR B;  3LWQ B;  3HJY B;  2APO B;  3HAX C;  3LWO B;  2AQC A; 
#chains in the Genus database with same CATH topology
 4G6B A;  1NNQ A;  1R0G A;  1FHM A;  3PKI A;  1LKO A;  1WCM L;  2XJS A;  3LNL A;  2Z3Q B;  1TWF L;  3S1M L;  2JA8 L;  3PWF A;  2M6P A;  2VL6 A;  5AI2 A;  3LWP B;  4YWL A;  4X6A L;  3B0A B;  2PVE A;  5M5X L;  4RXN A;  3I4N L;  3HOX L;  4C3J L;  1B2O A;  1IW7 D;  4AHW A;  4BY1 L;  4BBS L;  3RYG A;  2XJU A;  1T9Q A;  3A44 A;  2H12 A;  5AN9 H;  1R0H A;  2PVX A;  5MFZ A;  2E2I L;  1P7P A;  4AR3 A;  4TVM A;  5C4J L;  1SFO L;  3GTO L;  2A68 D;  4XGH A;  3LWO B;  4AI1 A;  2CR8 A;  4A3F L;  4BXX L;  7RXN A;  1TWG L;  1TWH L;  2ERJ A;  5AI3 A;  3J7Y 1;  2A6H D;  3S15 L;  1SMU A;  2JA5 L;  2NYD A;  4ME3 A;  1B71 A;  1CAD A;  2NVY L;  2XJQ A;  2E2J L;  4AHY A;  1YUZ A;  3GTK L;  3KYU A;  4AR5 A;  5MF6 A;  1S2Z A;  3P2A A;  2B63 L;  1YK5 A;  3P8B A;  5JVG 1;  1B2J A;  5GAH c;  3MQK B;  1S24 A;  1K83 L;  2EY4 E;  3CQZ L;  2WAQ P;  2A6E D;  5GAG c;  5MGN A;  2E2H L;  3IU3 I;  5IYB L;  3WWN B;  1OWC A;  4A3B L;  1DVB A;  3H9B A;  4E6Y A;  2HVY C;  1S30 A;  4A3E L;  1PFV A;  3HOV L;  1IRN A;  1VZI A;  1C09 A;  1VCX A;  1F4L A;  1LKM A;  2JI1 A;  2XJT A;  3S17 L;  3HOW L;  3S1N L;  1DX8 A;  3M3Y L;  5DM6 1;  5C44 L;  1PFY A;  3S1R L;  4GS7 D;  2GMG A;  5GAD c;  2PYA A;  4JAF A;  2CKA A;  3KYW A;  3SS2 A;  4A3L L;  4LHN A;  5EIO C;  1NXG A;  3LWR B;  5C3E L;  5M5Y L;  2JA6 L;  4V19 6;  2LCQ A;  2HR5 A;  1I3Q L;  1JYB A;  4Y7N L;  2CKC A;  1B13 A;  3S14 L;  3H0G L;  3HJY B;  2ERS A;  3KYV A;  5FLM L;  1RYT A;  4JAG A;  3LPE B;  4BBR L;  2PPT A;  2ZIX A;  2QL0 A;  2M6O A;  4JAD A;  4AI2 A;  4WFN 1;  3PL5 A;  1I50 L;  2KKD A;  2XJR A;  1PFW A;  5M3F L;  4A3K L;  4Y52 L;  5JVH 1;  3S1Q L;  4A3M L;  3KYX A;  1PFU A;  2JA7 L;  3HJW B;  3S2H L;  3S2D L;  2APO B;  4BY7 L;  3NFP I;  2PMZ P;  3RZT A;  1BE7 A;  5IP7 L;  3HKZ P;  1R0J A;  4QIW P;  4POF A;  3H97 A;  1R0F A;  2V0F A;  2L0Z A;  4XXB B;  5IY0 A;  1BQ9 A;  3HOZ L;  1H7V A;  3JR7 A;  5RXN A;  2WB1 P;  2R7Z L;  1Y1W L;  3FDJ A;  1IRO A;  3PO3 L;  2AQC A;  4B8C D;  4LHL A;  3FKI L;  1T9O A;  3J7Z 1;  2V0E A;  1T9P A;  1YK4 A;  5IYC L;  3GTL L;  1CAA A;  4AHX A;  2R93 L;  3GTQ L;  1NXE A;  4C3H L;  3LWQ B;  1RDV A;  4A3D L;  2NVQ L;  1LTL A;  3ZG6 A;  1TWC L;  5H1S c;  3K35 A;  3QQC E;  1SMW A;  1R0I A;  1RDG A;  2M4V A;  1R9T L;  3GTG L;  1QYB A;  2KN9 A;  5GAE c;  4U67 1;  4A3G L;  2XJV A;  2A69 D;  3KYY A;  2JI3 A;  1QCV A;  1OWB A;  2J9U B;  4TPU A;  1Y1V L;  1IU6 A;  2C6B A;  5C4X L;  3PIP 1;  4AYB P;  5FJ8 L;  4C2M 1;  4A3C L;  2MS3 A;  3PO2 L;  4A3J L;  2R92 L;  4A3I L;  2Z3R B;  4AI3 A;  3PZA A;  3WWL A;  3GTP L;  1LKP A;  2C6A A;  1BFY A;  3H99 A;  5DM7 1;  1YV1 A;  3PIO 1;  5IYD L;  3GTM L;  1TWA L;  2BE5 D;  2Y0S P;  2YU9 L;  3RZD L;  1QQT A;  3MSU A;  1RWD A;  4C3I L;  3VPB E;  2JI2 A;  2AUS B;  1YUX A;  3MPS A;  6RXN A;  5IP9 L;  2M4Y A;  3LWV B;  5M3M L;  4ZN3 B;  1BQ8 A;  4AHZ A;  4K9F A;  1IU5 A;  1E8J A;  5EIN C;  3HOU L;  1WJV A;  1VZG A;  1Z92 B;  4AR6 A;  3K7A L;  3RZ6 A;  4POG A;  2V3B B;  3B08 B;  1I6H L;  3HAX C;  4UY8 1;  2RFK B;  4AR4 A;  2B5I D;  5K2M E;  1RB9 A;  2XJP A;  3I4M L;  4AI0 A;  5MFP A;  2O5J D;  1RYQ A;  3M4O L;  1BRF A;  1SMM A;  5M5W L;  1VZH A;  2NVT L;  4ZN1 B;  8RXN A;  2DSX A;  1FHH A;  4YWM A;  1ODH A;  3PKJ A;  2RDV A;  2K2D A;  1PZX A;  3QVD A;  3H9C A;  2NVX L;  3GTJ L;  2AYJ A;  1ZRP A;  5MLC 3;  3RZO L;  4JAE A;  3HOY L;  2VUM L;  2PSM C;  3S16 L;  3H3V M;  4A93 L; 
#chains in the Genus database with same CATH homology
 2AUS B;  2HVY C;  3LWP B;  3MQK B;  2RFK B;  3LWV B;  2EY4 E;  3HJW B;  3LWR B;  3LWQ B;  3HJY B;  2APO B;  3HAX C;  3LWO B;  2AQC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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