3LWVB

Structure of h/aca rnp bound to a substrate rna containing 2'-deoxyuridine
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
53
structure length
53
Chain Sequence
FRIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLGI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase .
pubmed doi rcsb
molecule tags Isomerase/rna binding protein/rna
source organism Pyrococcus furiosus
molecule keywords Pseudouridine synthase Cbf5
total genus 7
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2010-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04135 Nop10p Nucleolar RNA-binding protein, Nop10p family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.40 Mainly Beta Single Sheet Rubrerythrin, domain 2 H/ACA ribonucleoprotein complex, subunit Nop10 3lwvB00
3LWVB 3LWRB 2AUSB 3LWOB 3HJYB 3LWQB 2RFKB 3HAXC 3HJWB 2APOB 3LWPB 2EY4E 2HVYC 3MQKB 2AQCA
chains in the Genus database with same CATH superfamily
3HOVL 3HAXC 3GTQL 1ODHA 3S15L 3H97A 4AHZA 2JA8L 1I3QL 2Z3QB 2Z3RB 4C3IL 3S1NL 1I6HL 1VZGA 1BFYA 1LKPA 3RYGA 1IU5A 1H7VA 1VZIA 5RXNA 1R0GA 1JYBA 2PYAA 2C6AA 2APOB 2WAQP 2A6HD 1BRFA 2M6OA 2B63L 1RYQA 1CAAA 5AI2A 3JR7A 1LTLA 4WFN1 3P8BA 3J7Z1 4AI2A 1SFOL 3GTJL 4BBSL 4C3JL 4A93L 2PVEA 4ME3A 2VUML 1SMUA 2B5ID 2XJPA 4A3CL 2V3BB 1RDVA 2R7ZL 2JA6L 4C2M1 2A69D 4A3DL 1YV1A 3PWFA 2E2JL 4A3GL 3PL5A 2A6ED 5GADc 3CQZL 5GAGc 3M4OL 2R93L 5EINC 1PFVA 2E2HL 1R9TL 1IRNA 4GS7D 1RYTA 5K2ME 4LHNA 5DM71 2CKCA 3MQKB 5C4JL 4JAFA 2DSXA 5GAHc 2CR8A 2ERSA 4AR4A 1R0IA 2NVYL 4A3BL 1B2OA 1WJVA 1QYBA 1RDGA 3LWQB 3HOWL 2L0ZA 4AI0A 2XJRA 5JVH1 3LPEB 3KYUA 4G6BA 4TVMA 5MF6A 3KYVA 5DM61 4YWMA 4AR3A 2HR5A 3KYXA 2A68D 4U671 4E6YA 3RZ6A 4A3JL 2WB1P 3PKJA 2YU9L 1QCVA 3HJYB 5M3ML 2XJTA 4JAEA 2NVQL 1IROA 1S2ZA 1BE7A 6RXNA 2RFKB 1QQTA 1NXGA 2XJVA 1T9QA 3PKIA 3H0GL 1TWGL 1RWDA 5IYBL 1I50L 2J9UB 3H9CA 2M4YA 3HOXL 1OWBA 3RZOL 1VZHA 2PVXA 4BBRL 1K83L 3I4NL 1PFYA 2VL6A 5FJ8L 1R0HA 1PZXA 3SS2A 4Y52L 5C3EL 5IP7L 5MGNA 2BE5D 4ZN3B 4AYBP 2PMZP 4UY81 2LCQA 1OWCA 1LKMA 2XJQA 3PIP1 5M5XL 3S16L 2K2DA 4XGHA 1TWCL 1R0JA 1DVBA 2AQCA 3S2DL 3GTML 8RXNA 4A3LL 3S1RL 3GTOL 1B71A 4XXBB 2C6BA 3K35A 2AUSB 1IW7D 3GTPL 2PPTA 3M3YL 1YUZA 4LHLA 3H3VM 5AI3A 2RDVA 4QIWP 3B0AB 2ERJA 2Y0SP 1RB9A 5IP9L 1TWHL 5MFPA 5IYDL 3PO2L 1TWAL 4BY1L 5H1Sc 1S24A 1B13A 3HOYL 3HKZP 5IY0A 3GTGL 3S2HL 3HJWB 3PIO1 4K9FA 5M5YL 3A44A 2JI3A 1CADA 4X6AL 1FHHA 7RXNA 1E8JA 1Y1WL 5GAEc 2KN9A 5M5WL 2XJUA 1YK4A 1BQ9A 2NVXL 2PSMC 3IU3I 1BQ8A 2NVTL 3NFPI 3LWOB 3RZDL 4JADA 4AI3A 3H99A 1DX8A 2XJSA 2KKDA 2GMGA 3HOUL 2R92L 3KYWA 3S14L 3KYYA 1NNQA 3LWPB 2H12A 1NXEA 1YUXA 1P7PA 4AHWA 4POGA 4AHXA 2JA7L 1LKOA 2HVYC 5EIOC 1YK5A 3B08B 5MFZA 3I4ML 1WCML 1SMMA 3H9BA 3FKIL 4AR6A 1IU6A 4AI1A 5MLC3 2V0FA 3WWLA 1VCXA 1C09A 4ZN1B 4AHYA 2NYDA 1F4LA 2O5JD 3P2AA 3HOZL 3S1ML 4POFA 2M4VA 2V0EA 3LNLA 1Y1VL 3J7Y1 3LWVB 4B8CD 4A3ML 5C4XL 2AYJA 3PZAA 3MPSA 5C44L 1PFUA 4RXNA 3VPBE 4A3IL 5M3FL 4A3FL 3QVDA 2ZIXA 2E2IL 4V196 4A3KL 1TWFL 2CKAA 4YWLA 2QL0A 4A3EL 3GTKL 4JAGA 1R0FA 1T9PA 5JVG1 5IYCL 4BXXL 3WWNB 1B2JA 3GTLL 3RZTA 4Y7NL 3FDJA 2JI2A 1Z92B 5AN9H 1FHMA 3PO3L 2M6PA 3S1QL 3ZG6A 2JA5L 1ZRPA 4TPUA 5FLML 3K7AL 2EY4E 1SMWA 1S30A 1PFWA 3MSUA 3LWRB 4C3HL 4BY7L 2JI1A 3QQCE 2MS3A 4AR5A 3S17L 1T9OA
chains in the Genus database with same CATH topology
3LWVB 3LWRB 2AUSB 3LWOB 3HJYB 3LWQB 2RFKB 3HAXC 3HJWB 2APOB 3LWPB 2EY4E 2HVYC 3MQKB 2AQCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LWV B;  3LWR B;  2AUS B;  3LWO B;  3HJY B;  3LWQ B;  2RFK B;  3HAX C;  3HJW B;  2APO B;  3LWP B;  2EY4 E;  2HVY C;  3MQK B;  2AQC A; 
#chains in the Genus database with same CATH topology
 3HOV L;  3HAX C;  3GTQ L;  1ODH A;  3S15 L;  3H97 A;  4AHZ A;  2JA8 L;  1I3Q L;  2Z3Q B;  2Z3R B;  4C3I L;  3S1N L;  1I6H L;  1VZG A;  1BFY A;  1LKP A;  3RYG A;  1IU5 A;  1H7V A;  1VZI A;  5RXN A;  1R0G A;  1JYB A;  2PYA A;  2C6A A;  2APO B;  2WAQ P;  2A6H D;  1BRF A;  2M6O A;  2B63 L;  1RYQ A;  1CAA A;  5AI2 A;  3JR7 A;  1LTL A;  4WFN 1;  3P8B A;  3J7Z 1;  4AI2 A;  1SFO L;  3GTJ L;  4BBS L;  4C3J L;  4A93 L;  2PVE A;  4ME3 A;  2VUM L;  1SMU A;  2B5I D;  2XJP A;  4A3C L;  2V3B B;  1RDV A;  2R7Z L;  2JA6 L;  4C2M 1;  2A69 D;  4A3D L;  1YV1 A;  3PWF A;  2E2J L;  4A3G L;  3PL5 A;  2A6E D;  5GAD c;  3CQZ L;  5GAG c;  3M4O L;  2R93 L;  5EIN C;  1PFV A;  2E2H L;  1R9T L;  1IRN A;  4GS7 D;  1RYT A;  5K2M E;  4LHN A;  5DM7 1;  2CKC A;  3MQK B;  5C4J L;  4JAF A;  2DSX A;  5GAH c;  2CR8 A;  2ERS A;  4AR4 A;  1R0I A;  2NVY L;  4A3B L;  1B2O A;  1WJV A;  1QYB A;  1RDG A;  3LWQ B;  3HOW L;  2L0Z A;  4AI0 A;  2XJR A;  5JVH 1;  3LPE B;  3KYU A;  4G6B A;  4TVM A;  5MF6 A;  3KYV A;  5DM6 1;  4YWM A;  4AR3 A;  2HR5 A;  3KYX A;  2A68 D;  4U67 1;  4E6Y A;  3RZ6 A;  4A3J L;  2WB1 P;  3PKJ A;  2YU9 L;  1QCV A;  3HJY B;  5M3M L;  2XJT A;  4JAE A;  2NVQ L;  1IRO A;  1S2Z A;  1BE7 A;  6RXN A;  2RFK B;  1QQT A;  1NXG A;  2XJV A;  1T9Q A;  3PKI A;  3H0G L;  1TWG L;  1RWD A;  5IYB L;  1I50 L;  2J9U B;  3H9C A;  2M4Y A;  3HOX L;  1OWB A;  3RZO L;  1VZH A;  2PVX A;  4BBR L;  1K83 L;  3I4N L;  1PFY A;  2VL6 A;  5FJ8 L;  1R0H A;  1PZX A;  3SS2 A;  4Y52 L;  5C3E L;  5IP7 L;  5MGN A;  2BE5 D;  4ZN3 B;  4AYB P;  2PMZ P;  4UY8 1;  2LCQ A;  1OWC A;  1LKM A;  2XJQ A;  3PIP 1;  5M5X L;  3S16 L;  2K2D A;  4XGH A;  1TWC L;  1R0J A;  1DVB A;  2AQC A;  3S2D L;  3GTM L;  8RXN A;  4A3L L;  3S1R L;  3GTO L;  1B71 A;  4XXB B;  2C6B A;  3K35 A;  2AUS B;  1IW7 D;  3GTP L;  2PPT A;  3M3Y L;  1YUZ A;  4LHL A;  3H3V M;  5AI3 A;  2RDV A;  4QIW P;  3B0A B;  2ERJ A;  2Y0S P;  1RB9 A;  5IP9 L;  1TWH L;  5MFP A;  5IYD L;  3PO2 L;  1TWA L;  4BY1 L;  5H1S c;  1S24 A;  1B13 A;  3HOY L;  3HKZ P;  5IY0 A;  3GTG L;  3S2H L;  3HJW B;  3PIO 1;  4K9F A;  5M5Y L;  3A44 A;  2JI3 A;  1CAD A;  4X6A L;  1FHH A;  7RXN A;  1E8J A;  1Y1W L;  5GAE c;  2KN9 A;  5M5W L;  2XJU A;  1YK4 A;  1BQ9 A;  2NVX L;  2PSM C;  3IU3 I;  1BQ8 A;  2NVT L;  3NFP I;  3LWO B;  3RZD L;  4JAD A;  4AI3 A;  3H99 A;  1DX8 A;  2XJS A;  2KKD A;  2GMG A;  3HOU L;  2R92 L;  3KYW A;  3S14 L;  3KYY A;  1NNQ A;  3LWP B;  2H12 A;  1NXE A;  1YUX A;  1P7P A;  4AHW A;  4POG A;  4AHX A;  2JA7 L;  1LKO A;  2HVY C;  5EIO C;  1YK5 A;  3B08 B;  5MFZ A;  3I4M L;  1WCM L;  1SMM A;  3H9B A;  3FKI L;  4AR6 A;  1IU6 A;  4AI1 A;  5MLC 3;  2V0F A;  3WWL A;  1VCX A;  1C09 A;  4ZN1 B;  4AHY A;  2NYD A;  1F4L A;  2O5J D;  3P2A A;  3HOZ L;  3S1M L;  4POF A;  2M4V A;  2V0E A;  3LNL A;  1Y1V L;  3J7Y 1;  3LWV B;  4B8C D;  4A3M L;  5C4X L;  2AYJ A;  3PZA A;  3MPS A;  5C44 L;  1PFU A;  4RXN A;  3VPB E;  4A3I L;  5M3F L;  4A3F L;  3QVD A;  2ZIX A;  2E2I L;  4V19 6;  4A3K L;  1TWF L;  2CKA A;  4YWL A;  2QL0 A;  4A3E L;  3GTK L;  4JAG A;  1R0F A;  1T9P A;  5JVG 1;  5IYC L;  4BXX L;  3WWN B;  1B2J A;  3GTL L;  3RZT A;  4Y7N L;  3FDJ A;  2JI2 A;  1Z92 B;  5AN9 H;  1FHM A;  3PO3 L;  2M6P A;  3S1Q L;  3ZG6 A;  2JA5 L;  1ZRP A;  4TPU A;  5FLM L;  3K7A L;  2EY4 E;  1SMW A;  1S30 A;  1PFW A;  3MSU A;  3LWR B;  4C3H L;  4BY7 L;  2JI1 A;  3QQC E;  2MS3 A;  4AR5 A;  3S17 L;  1T9O A; 
#chains in the Genus database with same CATH homology
 3LWV B;  3LWR B;  2AUS B;  3LWO B;  3HJY B;  3LWQ B;  2RFK B;  3HAX C;  3HJW B;  2APO B;  3LWP B;  2EY4 E;  2HVY C;  3MQK B;  2AQC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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