3P71C

Crystal structure of the complex of lcmt-1 and pp2a
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
303
structure length
303
Chain Sequence
DEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPHVTRRTPDYFL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structural Basis for Tight Control of PP2A Methylation and Function by LCMT-1.
pubmed doi rcsb
molecule tags Transferase/hydrolase
source organism Homo sapiens
molecule keywords Leucine carboxyl methyltransferase 1
total genus 110
structure length 303
sequence length 303
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2010-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3p71C00
1S3LA 2NYLC 3THNA 4LTYA 4NZVA 3TGHA 3IB7A 5JJTA 4MOYA 5IOHA 1AUIA 4ORBA 2NYMC 4H1SA 4KBPA 1HP1A 1Z2WA 5C1VA 3RQZA 3H64A 2IE3C 1U32A 4TUIA 3EGGA 1S3NA 4HD0A 3C5WC 3P71C 3DSDA 2P6BA 2QFRA 1W24A 3QFOA 3V4YA 3DSCA 2WDDA 2NXFA 4O4KA 1II7A 4V0VA 2HY1A 3H61A 4J6OA 2NPPC 4DHLA 4FCXA 1UTEA 3THOB 3EGHA 2USHA 3QG5C 4B2OA 1Z2XA 1SU1A 1NNWA 3RL3A 3KBPA 3C9FA 4I5NC 4ORCA 3ICFA 4ZX2A 5INBA 1FJMA 2IE4C 4H1YP 2IAEC 5J28A 2KKNA 2O8AA 3H68A 4IYPC 3QFNA 4ZVZA 1HPUA 2DFJA 4DT2A 3K7VC 1G5BA 5HPEA 3FGAC 2Z06A 3PSNA 4WWLA 4I5LC 3H60A 3IB8A 3H62B 4OR9A 1USHA 4V0XA 1WARA 3LL8A 3ZTVA 1T70A 4FBWA 2Q8UA 4JA9A 2QFPA 3CK2A 4O43A 4O5GA 1QFCA 4ORAA 5B8IA 2O8GA 3E7AA 4XPNA 5EQVA 3IVEA 2YVTA 4Q7FA 3H69A 4TUGA 4H2FA 1KBPA 4IL1A 2WDFA 3RL4A 2BDXA 2GJUA 3GVEA 1UF3A 1S8EA 2BCDA 3H67A 3HVQA 4DSYA 1WAO1 4LACC 4KKZA 1QHWA 4H2GA 2WDEA 4MP0A 3K7WC 3DW8C 5F3WA 2HYOA 2R17A 1S95A 2BQ8X 2HYPA 1JK7A 1T71A 3IVDA 3PSOA 4UT3A 3AUZA 3ZU0A 5DNYA 2WDCA 3RL5A 3AV0A 4JA7A 1V73A 1OIEA 1XZWA 2JOGA 2Z1AA 1MF8A 4UWQA 4G9JA 4F0ZA 4H2BA 4UT3B 5GTUA 2CV9A 4M0VA 1TCOA 3JYFA 2ZBMA 1S3MA 3H63A 5JPFA 3QFKA 3H66A 2QJCA 4MOVA 3QFMA 2XMOA 3N5UA 1IT6A 2A22A 2AHDA 1OIDA 4V0WA 4FBQA 1OI8A 1XM7A 1S70A 1HO5A 4UT2A 3T1IA 5JPEA 4O24A 4YKEA 1M63A 3E7BA 4LU9A 2Z72A 4FBKA 4H2IA
chains in the Genus database with same CATH superfamily
1S3LA 2NYLC 3THNA 4LTYA 4NZVA 3TGHA 3IB7A 5JJTA 4MOYA 5IOHA 1AUIA 4ORBA 2NYMC 4H1SA 4KBPA 1HP1A 1Z2WA 5C1VA 3RQZA 3H64A 2IE3C 1U32A 4TUIA 3EGGA 1S3NA 4HD0A 3C5WC 3P71C 3DSDA 2P6BA 2QFRA 1W24A 3QFOA 3V4YA 3DSCA 2WDDA 2NXFA 4O4KA 1II7A 3D03A 4V0VA 2HY1A 3H61A 4J6OA 2NPPC 4DHLA 4FCXA 1UTEA 3THOB 3EGHA 2USHA 3QG5C 4B2OA 3E0JA 1Z2XA 1SU1A 1NNWA 3RL3A 3KBPA 3C9FA 4I5NC 4ORCA 3ICFA 4ZX2A 5INBA 1FJMA 2IE4C 4H1YP 2IAEC 5J28A 2KKNA 2O8AA 3H68A 4IYPC 3QFNA 4ZVZA 1HPUA 2DFJA 4DT2A 3K7VC 1G5BA 5HPEA 3FGAC 2Z06A 3PSNA 2ZO9B 4I5LC 4WWLA 3H60A 3IB8A 3H62B 2ZOAA 4OR9A 1USHA 4V0XA 1WARA 3LL8A 3ZTVA 1T70A 4FBWA 2Q8UA 4JA9A 2QFPA 3CK2A 4O43A 4O5GA 1QFCA 4ORAA 5B8IA 2O8GA 3E7AA 4XPNA 5EQVA 3IVEA 2YVTA 4Q7FA 3H69A 4TUGA 4H2FA 1KBPA 4IL1A 2WDFA 3RL4A 2BDXA 2GJUA 3GVEA 1UF3A 1S8EA 2BCDA 3H67A 3HVQA 4DSYA 1WAO1 4LACC 4KKZA 1QHWA 4H2GA 2WDEA 4MP0A 3K7WC 3DW8C 5F3WA 2HYOA 2R17A 1S95A 2BQ8X 2HYPA 1JK7A 1T71A 3IVDA 3PSOA 4UT3A 3AUZA 3ZU0A 5DNYA 2DXLA 2WDCA 3RL5A 3AV0A 4JA7A 1V73A 1OIEA 1XZWA 2JOGA 2YEQA 2Z1AA 1MF8A 4UWQA 4G9JA 4F0ZA 4H2BA 4UT3B 5GTUA 2CV9A 4M0VA 1TCOA 3JYFA 2ZBMA 1S3MA 3H63A 5JPFA 3QFKA 3H66A 2QJCA 4MOVA 3QFMA 2XMOA 3FLOA 3N5UA 1IT6A 2A22A 2AHDA 1OIDA 4V0WA 4FBQA 1OI8A 1XM7A 1S70A 1HO5A 4UT2A 3T1IA 5JPEA 4O24A 4YKEA 1M63A 3E7BA 4LU9A 2DXNA 2Z72A 4FBKA 4H2IA
chains in the Genus database with same CATH topology
1S3LA 2NYLC 3THNA 4LTYA 4NZVA 3TGHA 3IB7A 5JJTA 4MOYA 5IOHA 1AUIA 4ORBA 2NYMC 4H1SA 4KBPA 1HP1A 1Z2WA 5C1VA 3RQZA 3H64A 2IE3C 1U32A 4TUIA 3EGGA 1S3NA 4HD0A 3C5WC 3P71C 3DSDA 2P6BA 2QFRA 1W24A 3QFOA 3V4YA 3DSCA 2WDDA 2NXFA 4O4KA 1II7A 3D03A 4V0VA 2HY1A 3H61A 4J6OA 2NPPC 4DHLA 4FCXA 1UTEA 3THOB 3EGHA 2USHA 3QG5C 4B2OA 3E0JA 1Z2XA 1SU1A 1NNWA 3RL3A 3KBPA 3C9FA 4I5NC 4ORCA 3ICFA 4ZX2A 5INBA 1FJMA 2IE4C 4H1YP 2IAEC 5J28A 2KKNA 2O8AA 3H68A 4IYPC 3QFNA 4ZVZA 1HPUA 2DFJA 4DT2A 3K7VC 1G5BA 5HPEA 3FGAC 2Z06A 3PSNA 2ZO9B 4I5LC 4WWLA 3H60A 3IB8A 3H62B 2ZOAA 4OR9A 1USHA 4V0XA 1WARA 3LL8A 3ZTVA 1T70A 4FBWA 2Q8UA 4JA9A 2QFPA 3CK2A 4O43A 4O5GA 1QFCA 4ORAA 5B8IA 2O8GA 3E7AA 4XPNA 5EQVA 3IVEA 2YVTA 4Q7FA 3H69A 4TUGA 4H2FA 1KBPA 4IL1A 2WDFA 3RL4A 2BDXA 2GJUA 3GVEA 1UF3A 1S8EA 2BCDA 3H67A 3HVQA 4DSYA 1WAO1 4LACC 4KKZA 1QHWA 4H2GA 2WDEA 4MP0A 3K7WC 3DW8C 5F3WA 2HYOA 2R17A 1S95A 2BQ8X 2HYPA 1JK7A 1T71A 3IVDA 3PSOA 4UT3A 3AUZA 3ZU0A 5DNYA 2DXLA 2WDCA 3RL5A 3AV0A 4JA7A 1V73A 1OIEA 1XZWA 2JOGA 2YEQA 2Z1AA 1MF8A 4UWQA 4G9JA 4F0ZA 4H2BA 4UT3B 5GTUA 2CV9A 4M0VA 1TCOA 3JYFA 2ZBMA 1S3MA 3H63A 5JPFA 3QFKA 3H66A 2QJCA 4MOVA 3QFMA 2XMOA 3FLOA 3N5UA 1IT6A 2A22A 2AHDA 1OIDA 4V0WA 4FBQA 1OI8A 1XM7A 1S70A 1HO5A 4UT2A 3T1IA 5JPEA 4O24A 4YKEA 1M63A 3E7BA 4LU9A 2DXNA 2Z72A 4FBKA 4H2IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S3L A;  2NYL C;  3THN A;  4LTY A;  4NZV A;  3TGH A;  3IB7 A;  5JJT A;  4MOY A;  5IOH A;  1AUI A;  4ORB A;  2NYM C;  4H1S A;  4KBP A;  1HP1 A;  1Z2W A;  5C1V A;  3RQZ A;  3H64 A;  2IE3 C;  1U32 A;  4TUI A;  3EGG A;  1S3N A;  4HD0 A;  3C5W C;  3P71 C;  3DSD A;  2P6B A;  2QFR A;  1W24 A;  3QFO A;  3V4Y A;  3DSC A;  2WDD A;  2NXF A;  4O4K A;  1II7 A;  4V0V A;  2HY1 A;  3H61 A;  4J6O A;  2NPP C;  4DHL A;  4FCX A;  1UTE A;  3THO B;  3EGH A;  2USH A;  3QG5 C;  4B2O A;  1Z2X A;  1SU1 A;  1NNW A;  3RL3 A;  3KBP A;  3C9F A;  4I5N C;  4ORC A;  3ICF A;  4ZX2 A;  5INB A;  1FJM A;  2IE4 C;  4H1Y P;  2IAE C;  5J28 A;  2KKN A;  2O8A A;  3H68 A;  4IYP C;  3QFN A;  4ZVZ A;  1HPU A;  2DFJ A;  4DT2 A;  3K7V C;  1G5B A;  5HPE A;  3FGA C;  2Z06 A;  3PSN A;  4WWL A;  4I5L C;  3H60 A;  3IB8 A;  3H62 B;  4OR9 A;  1USH A;  4V0X A;  1WAR A;  3LL8 A;  3ZTV A;  1T70 A;  4FBW A;  2Q8U A;  4JA9 A;  2QFP A;  3CK2 A;  4O43 A;  4O5G A;  1QFC A;  4ORA A;  5B8I A;  2O8G A;  3E7A A;  4XPN A;  5EQV A;  3IVE A;  2YVT A;  4Q7F A;  3H69 A;  4TUG A;  4H2F A;  1KBP A;  4IL1 A;  2WDF A;  3RL4 A;  2BDX A;  2GJU A;  3GVE A;  1UF3 A;  1S8E A;  2BCD A;  3H67 A;  3HVQ A;  4DSY A;  1WAO 1;  4LAC C;  4KKZ A;  1QHW A;  4H2G A;  2WDE A;  4MP0 A;  3K7W C;  3DW8 C;  5F3W A;  2HYO A;  2R17 A;  1S95 A;  2BQ8 X;  2HYP A;  1JK7 A;  1T71 A;  3IVD A;  3PSO A;  4UT3 A;  3AUZ A;  3ZU0 A;  5DNY A;  2WDC A;  3RL5 A;  3AV0 A;  4JA7 A;  1V73 A;  1OIE A;  1XZW A;  2JOG A;  2Z1A A;  1MF8 A;  4UWQ A;  4G9J A;  4F0Z A;  4H2B A;  4UT3 B;  5GTU A;  2CV9 A;  4M0V A;  1TCO A;  3JYF A;  2ZBM A;  1S3M A;  3H63 A;  5JPF A;  3QFK A;  3H66 A;  2QJC A;  4MOV A;  3QFM A;  2XMO A;  3N5U A;  1IT6 A;  2A22 A;  2AHD A;  1OID A;  4V0W A;  4FBQ A;  1OI8 A;  1XM7 A;  1S70 A;  1HO5 A;  4UT2 A;  3T1I A;  5JPE A;  4O24 A;  4YKE A;  1M63 A;  3E7B A;  4LU9 A;  2Z72 A;  4FBK A;  4H2I A; 
#chains in the Genus database with same CATH topology
 1S3L A;  2NYL C;  3THN A;  4LTY A;  4NZV A;  3TGH A;  3IB7 A;  5JJT A;  4MOY A;  5IOH A;  1AUI A;  4ORB A;  2NYM C;  4H1S A;  4KBP A;  1HP1 A;  1Z2W A;  5C1V A;  3RQZ A;  3H64 A;  2IE3 C;  1U32 A;  4TUI A;  3EGG A;  1S3N A;  4HD0 A;  3C5W C;  3P71 C;  3DSD A;  2P6B A;  2QFR A;  1W24 A;  3QFO A;  3V4Y A;  3DSC A;  2WDD A;  2NXF A;  4O4K A;  1II7 A;  3D03 A;  4V0V A;  2HY1 A;  3H61 A;  4J6O A;  2NPP C;  4DHL A;  4FCX A;  1UTE A;  3THO B;  3EGH A;  2USH A;  3QG5 C;  4B2O A;  3E0J A;  1Z2X A;  1SU1 A;  1NNW A;  3RL3 A;  3KBP A;  3C9F A;  4I5N C;  4ORC A;  3ICF A;  4ZX2 A;  5INB A;  1FJM A;  2IE4 C;  4H1Y P;  2IAE C;  5J28 A;  2KKN A;  2O8A A;  3H68 A;  4IYP C;  3QFN A;  4ZVZ A;  1HPU A;  2DFJ A;  4DT2 A;  3K7V C;  1G5B A;  5HPE A;  3FGA C;  2Z06 A;  3PSN A;  2ZO9 B;  4I5L C;  4WWL A;  3H60 A;  3IB8 A;  3H62 B;  2ZOA A;  4OR9 A;  1USH A;  4V0X A;  1WAR A;  3LL8 A;  3ZTV A;  1T70 A;  4FBW A;  2Q8U A;  4JA9 A;  2QFP A;  3CK2 A;  4O43 A;  4O5G A;  1QFC A;  4ORA A;  5B8I A;  2O8G A;  3E7A A;  4XPN A;  5EQV A;  3IVE A;  2YVT A;  4Q7F A;  3H69 A;  4TUG A;  4H2F A;  1KBP A;  4IL1 A;  2WDF A;  3RL4 A;  2BDX A;  2GJU A;  3GVE A;  1UF3 A;  1S8E A;  2BCD A;  3H67 A;  3HVQ A;  4DSY A;  1WAO 1;  4LAC C;  4KKZ A;  1QHW A;  4H2G A;  2WDE A;  4MP0 A;  3K7W C;  3DW8 C;  5F3W A;  2HYO A;  2R17 A;  1S95 A;  2BQ8 X;  2HYP A;  1JK7 A;  1T71 A;  3IVD A;  3PSO A;  4UT3 A;  3AUZ A;  3ZU0 A;  5DNY A;  2DXL A;  2WDC A;  3RL5 A;  3AV0 A;  4JA7 A;  1V73 A;  1OIE A;  1XZW A;  2JOG A;  2YEQ A;  2Z1A A;  1MF8 A;  4UWQ A;  4G9J A;  4F0Z A;  4H2B A;  4UT3 B;  5GTU A;  2CV9 A;  4M0V A;  1TCO A;  3JYF A;  2ZBM A;  1S3M A;  3H63 A;  5JPF A;  3QFK A;  3H66 A;  2QJC A;  4MOV A;  3QFM A;  2XMO A;  3FLO A;  3N5U A;  1IT6 A;  2A22 A;  2AHD A;  1OID A;  4V0W A;  4FBQ A;  1OI8 A;  1XM7 A;  1S70 A;  1HO5 A;  4UT2 A;  3T1I A;  5JPE A;  4O24 A;  4YKE A;  1M63 A;  3E7B A;  4LU9 A;  2DXN A;  2Z72 A;  4FBK A;  4H2I A; 
#chains in the Genus database with same CATH homology
 1S3L A;  2NYL C;  3THN A;  4LTY A;  4NZV A;  3TGH A;  3IB7 A;  5JJT A;  4MOY A;  5IOH A;  1AUI A;  4ORB A;  2NYM C;  4H1S A;  4KBP A;  1HP1 A;  1Z2W A;  5C1V A;  3RQZ A;  3H64 A;  2IE3 C;  1U32 A;  4TUI A;  3EGG A;  1S3N A;  4HD0 A;  3C5W C;  3P71 C;  3DSD A;  2P6B A;  2QFR A;  1W24 A;  3QFO A;  3V4Y A;  3DSC A;  2WDD A;  2NXF A;  4O4K A;  1II7 A;  3D03 A;  4V0V A;  2HY1 A;  3H61 A;  4J6O A;  2NPP C;  4DHL A;  4FCX A;  1UTE A;  3THO B;  3EGH A;  2USH A;  3QG5 C;  4B2O A;  3E0J A;  1Z2X A;  1SU1 A;  1NNW A;  3RL3 A;  3KBP A;  3C9F A;  4I5N C;  4ORC A;  3ICF A;  4ZX2 A;  5INB A;  1FJM A;  2IE4 C;  4H1Y P;  2IAE C;  5J28 A;  2KKN A;  2O8A A;  3H68 A;  4IYP C;  3QFN A;  4ZVZ A;  1HPU A;  2DFJ A;  4DT2 A;  3K7V C;  1G5B A;  5HPE A;  3FGA C;  2Z06 A;  3PSN A;  2ZO9 B;  4I5L C;  4WWL A;  3H60 A;  3IB8 A;  3H62 B;  2ZOA A;  4OR9 A;  1USH A;  4V0X A;  1WAR A;  3LL8 A;  3ZTV A;  1T70 A;  4FBW A;  2Q8U A;  4JA9 A;  2QFP A;  3CK2 A;  4O43 A;  4O5G A;  1QFC A;  4ORA A;  5B8I A;  2O8G A;  3E7A A;  4XPN A;  5EQV A;  3IVE A;  2YVT A;  4Q7F A;  3H69 A;  4TUG A;  4H2F A;  1KBP A;  4IL1 A;  2WDF A;  3RL4 A;  2BDX A;  2GJU A;  3GVE A;  1UF3 A;  1S8E A;  2BCD A;  3H67 A;  3HVQ A;  4DSY A;  1WAO 1;  4LAC C;  4KKZ A;  1QHW A;  4H2G A;  2WDE A;  4MP0 A;  3K7W C;  3DW8 C;  5F3W A;  2HYO A;  2R17 A;  1S95 A;  2BQ8 X;  2HYP A;  1JK7 A;  1T71 A;  3IVD A;  3PSO A;  4UT3 A;  3AUZ A;  3ZU0 A;  5DNY A;  2DXL A;  2WDC A;  3RL5 A;  3AV0 A;  4JA7 A;  1V73 A;  1OIE A;  1XZW A;  2JOG A;  2YEQ A;  2Z1A A;  1MF8 A;  4UWQ A;  4G9J A;  4F0Z A;  4H2B A;  4UT3 B;  5GTU A;  2CV9 A;  4M0V A;  1TCO A;  3JYF A;  2ZBM A;  1S3M A;  3H63 A;  5JPF A;  3QFK A;  3H66 A;  2QJC A;  4MOV A;  3QFM A;  2XMO A;  3FLO A;  3N5U A;  1IT6 A;  2A22 A;  2AHD A;  1OID A;  4V0W A;  4FBQ A;  1OI8 A;  1XM7 A;  1S70 A;  1HO5 A;  4UT2 A;  3T1I A;  5JPE A;  4O24 A;  4YKE A;  1M63 A;  3E7B A;  4LU9 A;  2DXN A;  2Z72 A;  4FBK A;  4H2I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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