3RL4A

Rat metallophosphodiesterase mpped2 g252h mutant
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
281
structure length
275
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGHIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
molecule keywords Metallophosphoesterase MPPED2
molecule tags Hydrolase
source organism Rattus norvegicus
total genus 91
structure length 275
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl4A00
3K7WC 3ICFA 2IAEC 1II7A 4FCXA 5B8IA 3K7VC 4O4KA 3TGHA 1IT6A 1Z2WA 2Q8UA 3H62B 5F3WA 1S70A 3FGAC 2GJUA 3ZU0A 2BCDA 2NYLC 3RQZA 4LU9A 1XM7A 3QFKA 5IOHA 3IB8A 5JPFA 4Q7FA 3KBPA 3T1IA 4B2OA 3H64A 1V73A 1USHA 5EQVA 3H63A 2ZBMA 4DHLA 1HPUA 4YKEA 4ORCA 4TUIA 1S8EA 2QJCA 3RL4A 4ORBA 2Z06A 1MF8A 4KKZA 3DW8C 4G9JA 1UTEA 1QHWA 4JA9A 4O43A 4DT2A 3N5UA 5DNYA 2HYOA 1W24A 2QFPA 2R17A 4H1YP 3QFNA 3H68A 3EGGA 3EGHA 2BQ8X 2IE3C 3JYFA 4V0XA 3LL8A 3V4YA 3DSCA 2A22A 3ZTVA 2JOGA 2DFJA 3QFOA 3DSDA 3THOB 2Z1AA 4M0VA 2P6BA 2AHDA 4F0ZA 4I5LC 3HVQA 4H2FA 1HO5A 2Z72A 1HP1A 3H61A 2KKNA 4H1SA 4ORAA 5HPEA 3E7AA 1JK7A 5JJTA 4FBKA 4H2IA 4H2GA 1AUIA 4V0VA 1SU1A 4FBQA 2USHA 1WARA 4UT3B 1OIEA 2O8GA 4OR9A 4XPNA 4MOVA 3E7BA 3QG5C 1S3LA 3RL5A 3IVDA 2IE4C 1G5BA 2NXFA 1T71A 1Z2XA 3RL3A 4ZVZA 3PSNA 1TCOA 4UT2A 5INBA 2QFRA 4LACC 1S3MA 4MP0A 4H2BA 4HD0A 2O8AA 2WDEA 2XMOA 3PSOA 1OIDA 4O24A 3GVEA 4IYPC 4J6OA 2HY1A 3THNA 3AUZA 3IVEA 4KBPA 2HYPA 3H60A 1T70A 2BDXA 3AV0A 3IB7A 1NNWA 4NZVA 4WWLA 1S95A 4DSYA 4ZX2A 3CK2A 3H66A 5GTUA 5C1VA 4LTYA 4V0WA 2NYMC 5JPEA 1OI8A 1UF3A 3C5WC 4FBWA 4UT3A 1QFCA 2WDDA 4UWQA 2WDCA 4IL1A 5J28A 3H69A 2WDFA 1S3NA 4JA7A 3QFMA 2CV9A 4O5GA 1U32A 2YVTA 1FJMA 4MOYA 1XZWA 3H67A 1M63A 3P71C 1KBPA 3C9FA 1WAO1 4TUGA 4I5NC 2NPPC
chains in the Genus database with same CATH superfamily
3K7WC 2ZOAA 3ICFA 2IAEC 1II7A 4FCXA 5B8IA 3K7VC 4O4KA 3TGHA 1IT6A 1Z2WA 2Q8UA 3H62B 5F3WA 1S70A 3FGAC 2GJUA 3ZU0A 2BCDA 2NYLC 3RQZA 4LU9A 1XM7A 3QFKA 5IOHA 3IB8A 5JPFA 3D03A 3KBPA 4Q7FA 3T1IA 4B2OA 3H64A 1V73A 1USHA 5EQVA 3H63A 2ZBMA 4DHLA 1HPUA 4YKEA 4ORCA 4TUIA 1S8EA 2QJCA 3RL4A 4ORBA 2Z06A 1MF8A 4KKZA 3DW8C 4G9JA 1UTEA 1QHWA 4JA9A 4O43A 4DT2A 3N5UA 5DNYA 2HYOA 1W24A 2QFPA 2R17A 4H1YP 3QFNA 3H68A 3EGGA 3EGHA 2BQ8X 2IE3C 3JYFA 4V0XA 3LL8A 3V4YA 3DSCA 2A22A 2DXLA 2ZO9B 3ZTVA 2JOGA 2DFJA 3QFOA 3DSDA 3THOB 2Z1AA 4M0VA 2P6BA 2AHDA 4F0ZA 2DXNA 4I5LC 3HVQA 4H2FA 1HO5A 2Z72A 1HP1A 3H61A 2KKNA 4H1SA 4ORAA 5HPEA 3E7AA 1JK7A 5JJTA 4FBKA 4H2IA 4H2GA 1AUIA 4V0VA 1SU1A 4FBQA 2USHA 1WARA 4UT3B 1OIEA 2O8GA 4OR9A 4XPNA 4MOVA 3E7BA 3QG5C 1S3LA 3RL5A 3IVDA 2IE4C 1G5BA 2NXFA 1T71A 1Z2XA 3RL3A 4ZVZA 3PSNA 1TCOA 4UT2A 5INBA 2QFRA 4LACC 1S3MA 4MP0A 4H2BA 4HD0A 2O8AA 2WDEA 2XMOA 3PSOA 1OIDA 4O24A 3GVEA 4IYPC 2YEQA 3FLOA 4J6OA 2HY1A 3THNA 3AUZA 3IVEA 4KBPA 2HYPA 3H60A 1T70A 2BDXA 3AV0A 3IB7A 1NNWA 4NZVA 4WWLA 1S95A 4DSYA 4ZX2A 3CK2A 3H66A 5GTUA 5C1VA 4LTYA 4V0WA 2NYMC 5JPEA 1OI8A 1UF3A 3C5WC 4FBWA 4UT3A 1QFCA 2WDDA 4UWQA 2WDCA 4IL1A 5J28A 3E0JA 3H69A 2WDFA 1S3NA 4JA7A 3QFMA 2CV9A 4O5GA 1U32A 1FJMA 2YVTA 4MOYA 1XZWA 3H67A 1M63A 3P71C 1KBPA 3C9FA 1WAO1 4TUGA 4I5NC 2NPPC
chains in the Genus database with same CATH topology
3K7WC 2ZOAA 3ICFA 2IAEC 1II7A 4FCXA 5B8IA 3K7VC 4O4KA 3TGHA 1IT6A 1Z2WA 2Q8UA 3H62B 5F3WA 1S70A 3FGAC 2GJUA 3ZU0A 2BCDA 2NYLC 3RQZA 4LU9A 1XM7A 3QFKA 5IOHA 3IB8A 5JPFA 3D03A 3KBPA 4Q7FA 3T1IA 4B2OA 3H64A 1V73A 1USHA 5EQVA 3H63A 2ZBMA 4DHLA 1HPUA 4YKEA 4ORCA 4TUIA 1S8EA 2QJCA 3RL4A 4ORBA 2Z06A 1MF8A 4KKZA 3DW8C 4G9JA 1UTEA 1QHWA 4JA9A 4O43A 4DT2A 3N5UA 5DNYA 2HYOA 1W24A 2QFPA 2R17A 4H1YP 3QFNA 3H68A 3EGGA 3EGHA 2BQ8X 2IE3C 3JYFA 4V0XA 3LL8A 3V4YA 3DSCA 2A22A 2DXLA 2ZO9B 3ZTVA 2JOGA 2DFJA 3QFOA 3DSDA 3THOB 2Z1AA 4M0VA 2P6BA 2AHDA 4F0ZA 2DXNA 4I5LC 3HVQA 4H2FA 1HO5A 2Z72A 1HP1A 3H61A 2KKNA 4H1SA 4ORAA 5HPEA 3E7AA 1JK7A 5JJTA 4FBKA 4H2IA 4H2GA 1AUIA 4V0VA 1SU1A 4FBQA 2USHA 1WARA 4UT3B 1OIEA 2O8GA 4OR9A 4XPNA 4MOVA 3E7BA 3QG5C 1S3LA 3RL5A 3IVDA 2IE4C 1G5BA 2NXFA 1T71A 1Z2XA 3RL3A 4ZVZA 3PSNA 1TCOA 4UT2A 5INBA 2QFRA 4LACC 1S3MA 4MP0A 4H2BA 4HD0A 2O8AA 2WDEA 2XMOA 3PSOA 1OIDA 4O24A 3GVEA 4IYPC 2YEQA 3FLOA 4J6OA 2HY1A 3THNA 3AUZA 3IVEA 4KBPA 2HYPA 3H60A 1T70A 2BDXA 3AV0A 3IB7A 1NNWA 4NZVA 4WWLA 1S95A 4DSYA 4ZX2A 3CK2A 3H66A 5GTUA 5C1VA 4LTYA 4V0WA 2NYMC 5JPEA 1OI8A 1UF3A 3C5WC 4FBWA 4UT3A 1QFCA 2WDDA 4UWQA 2WDCA 4IL1A 5J28A 3E0JA 3H69A 2WDFA 1S3NA 4JA7A 3QFMA 2CV9A 4O5GA 1U32A 1FJMA 2YVTA 4MOYA 1XZWA 3H67A 1M63A 3P71C 1KBPA 3C9FA 1WAO1 4TUGA 4I5NC 2NPPC
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3K7W C;  3ICF A;  2IAE C;  1II7 A;  4FCX A;  5B8I A;  3K7V C;  4O4K A;  3TGH A;  1IT6 A;  1Z2W A;  2Q8U A;  3H62 B;  5F3W A;  1S70 A;  3FGA C;  2GJU A;  3ZU0 A;  2BCD A;  2NYL C;  3RQZ A;  4LU9 A;  1XM7 A;  3QFK A;  5IOH A;  3IB8 A;  5JPF A;  4Q7F A;  3KBP A;  3T1I A;  4B2O A;  3H64 A;  1V73 A;  1USH A;  5EQV A;  3H63 A;  2ZBM A;  4DHL A;  1HPU A;  4YKE A;  4ORC A;  4TUI A;  1S8E A;  2QJC A;  3RL4 A;  4ORB A;  2Z06 A;  1MF8 A;  4KKZ A;  3DW8 C;  4G9J A;  1UTE A;  1QHW A;  4JA9 A;  4O43 A;  4DT2 A;  3N5U A;  5DNY A;  2HYO A;  1W24 A;  2QFP A;  2R17 A;  4H1Y P;  3QFN A;  3H68 A;  3EGG A;  3EGH A;  2BQ8 X;  2IE3 C;  3JYF A;  4V0X A;  3LL8 A;  3V4Y A;  3DSC A;  2A22 A;  3ZTV A;  2JOG A;  2DFJ A;  3QFO A;  3DSD A;  3THO B;  2Z1A A;  4M0V A;  2P6B A;  2AHD A;  4F0Z A;  4I5L C;  3HVQ A;  4H2F A;  1HO5 A;  2Z72 A;  1HP1 A;  3H61 A;  2KKN A;  4H1S A;  4ORA A;  5HPE A;  3E7A A;  1JK7 A;  5JJT A;  4FBK A;  4H2I A;  4H2G A;  1AUI A;  4V0V A;  1SU1 A;  4FBQ A;  2USH A;  1WAR A;  4UT3 B;  1OIE A;  2O8G A;  4OR9 A;  4XPN A;  4MOV A;  3E7B A;  3QG5 C;  1S3L A;  3RL5 A;  3IVD A;  2IE4 C;  1G5B A;  2NXF A;  1T71 A;  1Z2X A;  3RL3 A;  4ZVZ A;  3PSN A;  1TCO A;  4UT2 A;  5INB A;  2QFR A;  4LAC C;  1S3M A;  4MP0 A;  4H2B A;  4HD0 A;  2O8A A;  2WDE A;  2XMO A;  3PSO A;  1OID A;  4O24 A;  3GVE A;  4IYP C;  4J6O A;  2HY1 A;  3THN A;  3AUZ A;  3IVE A;  4KBP A;  2HYP A;  3H60 A;  1T70 A;  2BDX A;  3AV0 A;  3IB7 A;  1NNW A;  4NZV A;  4WWL A;  1S95 A;  4DSY A;  4ZX2 A;  3CK2 A;  3H66 A;  5GTU A;  5C1V A;  4LTY A;  4V0W A;  2NYM C;  5JPE A;  1OI8 A;  1UF3 A;  3C5W C;  4FBW A;  4UT3 A;  1QFC A;  2WDD A;  4UWQ A;  2WDC A;  4IL1 A;  5J28 A;  3H69 A;  2WDF A;  1S3N A;  4JA7 A;  3QFM A;  2CV9 A;  4O5G A;  1U32 A;  2YVT A;  1FJM A;  4MOY A;  1XZW A;  3H67 A;  1M63 A;  3P71 C;  1KBP A;  3C9F A;  1WAO 1;  4TUG A;  4I5N C;  2NPP C; 
#chains in the Genus database with same CATH topology
 3K7W C;  2ZOA A;  3ICF A;  2IAE C;  1II7 A;  4FCX A;  5B8I A;  3K7V C;  4O4K A;  3TGH A;  1IT6 A;  1Z2W A;  2Q8U A;  3H62 B;  5F3W A;  1S70 A;  3FGA C;  2GJU A;  3ZU0 A;  2BCD A;  2NYL C;  3RQZ A;  4LU9 A;  1XM7 A;  3QFK A;  5IOH A;  3IB8 A;  5JPF A;  3D03 A;  3KBP A;  4Q7F A;  3T1I A;  4B2O A;  3H64 A;  1V73 A;  1USH A;  5EQV A;  3H63 A;  2ZBM A;  4DHL A;  1HPU A;  4YKE A;  4ORC A;  4TUI A;  1S8E A;  2QJC A;  3RL4 A;  4ORB A;  2Z06 A;  1MF8 A;  4KKZ A;  3DW8 C;  4G9J A;  1UTE A;  1QHW A;  4JA9 A;  4O43 A;  4DT2 A;  3N5U A;  5DNY A;  2HYO A;  1W24 A;  2QFP A;  2R17 A;  4H1Y P;  3QFN A;  3H68 A;  3EGG A;  3EGH A;  2BQ8 X;  2IE3 C;  3JYF A;  4V0X A;  3LL8 A;  3V4Y A;  3DSC A;  2A22 A;  2DXL A;  2ZO9 B;  3ZTV A;  2JOG A;  2DFJ A;  3QFO A;  3DSD A;  3THO B;  2Z1A A;  4M0V A;  2P6B A;  2AHD A;  4F0Z A;  2DXN A;  4I5L C;  3HVQ A;  4H2F A;  1HO5 A;  2Z72 A;  1HP1 A;  3H61 A;  2KKN A;  4H1S A;  4ORA A;  5HPE A;  3E7A A;  1JK7 A;  5JJT A;  4FBK A;  4H2I A;  4H2G A;  1AUI A;  4V0V A;  1SU1 A;  4FBQ A;  2USH A;  1WAR A;  4UT3 B;  1OIE A;  2O8G A;  4OR9 A;  4XPN A;  4MOV A;  3E7B A;  3QG5 C;  1S3L A;  3RL5 A;  3IVD A;  2IE4 C;  1G5B A;  2NXF A;  1T71 A;  1Z2X A;  3RL3 A;  4ZVZ A;  3PSN A;  1TCO A;  4UT2 A;  5INB A;  2QFR A;  4LAC C;  1S3M A;  4MP0 A;  4H2B A;  4HD0 A;  2O8A A;  2WDE A;  2XMO A;  3PSO A;  1OID A;  4O24 A;  3GVE A;  4IYP C;  2YEQ A;  3FLO A;  4J6O A;  2HY1 A;  3THN A;  3AUZ A;  3IVE A;  4KBP A;  2HYP A;  3H60 A;  1T70 A;  2BDX A;  3AV0 A;  3IB7 A;  1NNW A;  4NZV A;  4WWL A;  1S95 A;  4DSY A;  4ZX2 A;  3CK2 A;  3H66 A;  5GTU A;  5C1V A;  4LTY A;  4V0W A;  2NYM C;  5JPE A;  1OI8 A;  1UF3 A;  3C5W C;  4FBW A;  4UT3 A;  1QFC A;  2WDD A;  4UWQ A;  2WDC A;  4IL1 A;  5J28 A;  3E0J A;  3H69 A;  2WDF A;  1S3N A;  4JA7 A;  3QFM A;  2CV9 A;  4O5G A;  1U32 A;  1FJM A;  2YVT A;  4MOY A;  1XZW A;  3H67 A;  1M63 A;  3P71 C;  1KBP A;  3C9F A;  1WAO 1;  4TUG A;  4I5N C;  2NPP C; 
#chains in the Genus database with same CATH homology
 3K7W C;  2ZOA A;  3ICF A;  2IAE C;  1II7 A;  4FCX A;  5B8I A;  3K7V C;  4O4K A;  3TGH A;  1IT6 A;  1Z2W A;  2Q8U A;  3H62 B;  5F3W A;  1S70 A;  3FGA C;  2GJU A;  3ZU0 A;  2BCD A;  2NYL C;  3RQZ A;  4LU9 A;  1XM7 A;  3QFK A;  5IOH A;  3IB8 A;  5JPF A;  3D03 A;  3KBP A;  4Q7F A;  3T1I A;  4B2O A;  3H64 A;  1V73 A;  1USH A;  5EQV A;  3H63 A;  2ZBM A;  4DHL A;  1HPU A;  4YKE A;  4ORC A;  4TUI A;  1S8E A;  2QJC A;  3RL4 A;  4ORB A;  2Z06 A;  1MF8 A;  4KKZ A;  3DW8 C;  4G9J A;  1UTE A;  1QHW A;  4JA9 A;  4O43 A;  4DT2 A;  3N5U A;  5DNY A;  2HYO A;  1W24 A;  2QFP A;  2R17 A;  4H1Y P;  3QFN A;  3H68 A;  3EGG A;  3EGH A;  2BQ8 X;  2IE3 C;  3JYF A;  4V0X A;  3LL8 A;  3V4Y A;  3DSC A;  2A22 A;  2DXL A;  2ZO9 B;  3ZTV A;  2JOG A;  2DFJ A;  3QFO A;  3DSD A;  3THO B;  2Z1A A;  4M0V A;  2P6B A;  2AHD A;  4F0Z A;  2DXN A;  4I5L C;  3HVQ A;  4H2F A;  1HO5 A;  2Z72 A;  1HP1 A;  3H61 A;  2KKN A;  4H1S A;  4ORA A;  5HPE A;  3E7A A;  1JK7 A;  5JJT A;  4FBK A;  4H2I A;  4H2G A;  1AUI A;  4V0V A;  1SU1 A;  4FBQ A;  2USH A;  1WAR A;  4UT3 B;  1OIE A;  2O8G A;  4OR9 A;  4XPN A;  4MOV A;  3E7B A;  3QG5 C;  1S3L A;  3RL5 A;  3IVD A;  2IE4 C;  1G5B A;  2NXF A;  1T71 A;  1Z2X A;  3RL3 A;  4ZVZ A;  3PSN A;  1TCO A;  4UT2 A;  5INB A;  2QFR A;  4LAC C;  1S3M A;  4MP0 A;  4H2B A;  4HD0 A;  2O8A A;  2WDE A;  2XMO A;  3PSO A;  1OID A;  4O24 A;  3GVE A;  4IYP C;  2YEQ A;  3FLO A;  4J6O A;  2HY1 A;  3THN A;  3AUZ A;  3IVE A;  4KBP A;  2HYP A;  3H60 A;  1T70 A;  2BDX A;  3AV0 A;  3IB7 A;  1NNW A;  4NZV A;  4WWL A;  1S95 A;  4DSY A;  4ZX2 A;  3CK2 A;  3H66 A;  5GTU A;  5C1V A;  4LTY A;  4V0W A;  2NYM C;  5JPE A;  1OI8 A;  1UF3 A;  3C5W C;  4FBW A;  4UT3 A;  1QFC A;  2WDD A;  4UWQ A;  2WDC A;  4IL1 A;  5J28 A;  3E0J A;  3H69 A;  2WDF A;  1S3N A;  4JA7 A;  3QFM A;  2CV9 A;  4O5G A;  1U32 A;  1FJM A;  2YVT A;  4MOY A;  1XZW A;  3H67 A;  1M63 A;  3P71 C;  1KBP A;  3C9F A;  1WAO 1;  4TUG A;  4I5N C;  2NPP C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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