3RL5A

Rat metallophosphodiesterase mpped2 h67r mutant
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
281
structure length
279
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTRSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Metallophosphoesterase MPPED2
publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 91
structure length 279
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl5A00
1XZWA 3RL5A 4ORAA 3RQZA 4KKZA 1S3NA 4JA7A 1T71A 4V0VA 3H60A 4O24A 2P6BA 3H68A 2DFJA 3KBPA 2CV9A 1HP1A 2BDXA 3DSDA 1OIDA 2Q8UA 4H2BA 1Z2XA 4H2GA 3QFMA 1II7A 5JJTA 3K7VC 4TUGA 4FBWA 4WWLA 2YVTA 3T1IA 2O8GA 4I5LC 3PSOA 2A22A 3CK2A 3H67A 1AUIA 1WAO1 2Z72A 3H66A 2XMOA 3THOB 2NYMC 3FGAC 4ZVZA 1USHA 1WARA 1S8EA 1MF8A 1S70A 2QJCA 1FJMA 3GVEA 4IL1A 3THNA 4ORCA 1HO5A 4UT3A 3PSNA 4J6OA 4O5GA 4H2IA 4O4KA 2HYOA 4HD0A 4DSYA 3IB7A 5HPEA 3EGHA 3IVEA 2QFRA 3QG5C 3QFOA 4IYPC 1OIEA 2NPPC 1S3MA 3DW8C 4G9JA 3H69A 3H64A 2IAEC 3K7WC 4LACC 5C1VA 3C5WC 3EGGA 5J28A 2BCDA 4O43A 2O8AA 3H62B 3P71C 2QFPA 3HVQA 4TUIA 2NXFA 4OR9A 2NYLC 2WDFA 2ZBMA 3QFNA 4I5NC 4F0ZA 3IVDA 4UWQA 3C9FA 1W24A 4B2OA 3QFKA 2Z06A 4H1SA 3LL8A 3AV0A 3RL4A 1M63A 4LU9A 4FBKA 4V0XA 3E7AA 4YKEA 4MP0A 2IE3C 4H2FA 1TCOA 4MOVA 5B8IA 4FBQA 4H1YP 4FCXA 3RL3A 3ICFA 1T70A 1S95A 2Z1AA 1HPUA 4MOYA 2USHA 1U32A 1QFCA 3DSCA 2HY1A 3TGHA 1IT6A 4ORBA 4XPNA 5GTUA 1OI8A 4V0WA 2IE4C 5IOHA 3E7BA 1G5BA 4NZVA 1JK7A 3ZTVA 1QHWA 2GJUA 3AUZA 1SU1A 2KKNA 3H63A 2R17A 1S3LA 1NNWA 1KBPA 5JPEA 5F3WA 5JPFA 2BQ8X 4LTYA 4Q7FA 3ZU0A 5EQVA 1UTEA 3IB8A 4DT2A 3V4YA 2AHDA 2WDCA 2WDDA 5DNYA 1Z2WA 2WDEA 1V73A 4DHLA 3H61A 3JYFA 4UT2A 4UT3B 4KBPA 5INBA 3N5UA 4M0VA 2HYPA 4ZX2A 1UF3A 2JOGA 4JA9A 1XM7A
chains in the Genus database with same CATH superfamily
1XZWA 3RL5A 4ORAA 3RQZA 4KKZA 1S3NA 4JA7A 1T71A 4V0VA 3H60A 4O24A 2P6BA 3H68A 2DFJA 3KBPA 2CV9A 1HP1A 2BDXA 3DSDA 1OIDA 2Q8UA 4H2BA 1Z2XA 4H2GA 3QFMA 1II7A 5JJTA 3K7VC 4TUGA 4FBWA 4WWLA 2YVTA 3T1IA 2O8GA 4I5LC 3PSOA 2A22A 3CK2A 3H67A 1AUIA 1WAO1 2Z72A 3H66A 2XMOA 3THOB 2NYMC 3FGAC 4ZVZA 1USHA 1WARA 1S8EA 1MF8A 1S70A 2QJCA 1FJMA 3GVEA 4IL1A 3THNA 4ORCA 1HO5A 4UT3A 3PSNA 4J6OA 4O5GA 4H2IA 4O4KA 2HYOA 4HD0A 4DSYA 3IB7A 5HPEA 3EGHA 3IVEA 2QFRA 3QG5C 3QFOA 4IYPC 1OIEA 2NPPC 1S3MA 3DW8C 4G9JA 3H69A 3H64A 3FLOA 2IAEC 3K7WC 4LACC 5C1VA 3C5WC 3EGGA 5J28A 2DXNA 2BCDA 2DXLA 2YEQA 4O43A 2O8AA 3H62B 3P71C 2QFPA 3HVQA 4TUIA 2NXFA 4OR9A 2NYLC 2WDFA 2ZBMA 2ZOAA 3QFNA 4I5NC 4F0ZA 3IVDA 4UWQA 3C9FA 1W24A 4B2OA 3QFKA 2Z06A 4H1SA 3LL8A 3AV0A 3RL4A 1M63A 4LU9A 4FBKA 4V0XA 3E7AA 4YKEA 4MP0A 2IE3C 4H2FA 1TCOA 4MOVA 5B8IA 4FBQA 4H1YP 4FCXA 3RL3A 3ICFA 1T70A 1S95A 2Z1AA 1HPUA 4MOYA 2USHA 1U32A 1QFCA 3DSCA 2HY1A 3TGHA 3D03A 1IT6A 4ORBA 4XPNA 5GTUA 1OI8A 4V0WA 2IE4C 5IOHA 3E7BA 1G5BA 4NZVA 1JK7A 3ZTVA 1QHWA 2GJUA 3AUZA 1SU1A 2KKNA 3H63A 2R17A 1S3LA 1NNWA 1KBPA 5JPEA 5F3WA 5JPFA 2BQ8X 4LTYA 4Q7FA 3ZU0A 5EQVA 1UTEA 3IB8A 4DT2A 3V4YA 2AHDA 3E0JA 2WDCA 2WDDA 5DNYA 1Z2WA 2WDEA 1V73A 4DHLA 3H61A 3JYFA 4UT2A 4UT3B 4KBPA 5INBA 3N5UA 4M0VA 2HYPA 2ZO9B 4ZX2A 1UF3A 2JOGA 4JA9A 1XM7A
chains in the Genus database with same CATH topology
1XZWA 3RL5A 4ORAA 3RQZA 4KKZA 1S3NA 4JA7A 1T71A 4V0VA 3H60A 4O24A 2P6BA 3H68A 2DFJA 3KBPA 2CV9A 1HP1A 2BDXA 3DSDA 1OIDA 2Q8UA 4H2BA 1Z2XA 4H2GA 3QFMA 1II7A 5JJTA 3K7VC 4TUGA 4FBWA 4WWLA 2YVTA 3T1IA 2O8GA 4I5LC 3PSOA 2A22A 3CK2A 3H67A 1AUIA 1WAO1 2Z72A 3H66A 2XMOA 3THOB 2NYMC 3FGAC 4ZVZA 1USHA 1WARA 1S8EA 1MF8A 1S70A 2QJCA 1FJMA 3GVEA 4IL1A 3THNA 4ORCA 1HO5A 4UT3A 3PSNA 4J6OA 4O5GA 4H2IA 4O4KA 2HYOA 4HD0A 4DSYA 3IB7A 5HPEA 3EGHA 3IVEA 2QFRA 3QG5C 3QFOA 4IYPC 1OIEA 2NPPC 1S3MA 3DW8C 4G9JA 3H69A 3H64A 3FLOA 2IAEC 3K7WC 4LACC 5C1VA 3C5WC 3EGGA 5J28A 2DXNA 2BCDA 2DXLA 2YEQA 4O43A 2O8AA 3H62B 3P71C 2QFPA 3HVQA 4TUIA 2NXFA 4OR9A 2NYLC 2WDFA 2ZBMA 2ZOAA 3QFNA 4I5NC 4F0ZA 3IVDA 4UWQA 3C9FA 1W24A 4B2OA 3QFKA 2Z06A 4H1SA 3LL8A 3AV0A 3RL4A 1M63A 4LU9A 4FBKA 4V0XA 3E7AA 4YKEA 4MP0A 2IE3C 4H2FA 1TCOA 4MOVA 5B8IA 4FBQA 4H1YP 4FCXA 3RL3A 3ICFA 1T70A 1S95A 2Z1AA 1HPUA 4MOYA 2USHA 1U32A 1QFCA 3DSCA 2HY1A 3TGHA 3D03A 1IT6A 4ORBA 4XPNA 5GTUA 1OI8A 4V0WA 2IE4C 5IOHA 3E7BA 1G5BA 4NZVA 1JK7A 3ZTVA 1QHWA 2GJUA 3AUZA 1SU1A 2KKNA 3H63A 2R17A 1S3LA 1NNWA 1KBPA 5JPEA 5F3WA 5JPFA 2BQ8X 4LTYA 4Q7FA 3ZU0A 5EQVA 1UTEA 3IB8A 4DT2A 3V4YA 2AHDA 3E0JA 2WDCA 2WDDA 5DNYA 1Z2WA 2WDEA 1V73A 4DHLA 3H61A 3JYFA 4UT2A 4UT3B 4KBPA 5INBA 3N5UA 4M0VA 2HYPA 2ZO9B 4ZX2A 1UF3A 2JOGA 4JA9A 1XM7A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1XZW A;  3RL5 A;  4ORA A;  3RQZ A;  4KKZ A;  1S3N A;  4JA7 A;  1T71 A;  4V0V A;  3H60 A;  4O24 A;  2P6B A;  3H68 A;  2DFJ A;  3KBP A;  2CV9 A;  1HP1 A;  2BDX A;  3DSD A;  1OID A;  2Q8U A;  4H2B A;  1Z2X A;  4H2G A;  3QFM A;  1II7 A;  5JJT A;  3K7V C;  4TUG A;  4FBW A;  4WWL A;  2YVT A;  3T1I A;  2O8G A;  4I5L C;  3PSO A;  2A22 A;  3CK2 A;  3H67 A;  1AUI A;  1WAO 1;  2Z72 A;  3H66 A;  2XMO A;  3THO B;  2NYM C;  3FGA C;  4ZVZ A;  1USH A;  1WAR A;  1S8E A;  1MF8 A;  1S70 A;  2QJC A;  1FJM A;  3GVE A;  4IL1 A;  3THN A;  4ORC A;  1HO5 A;  4UT3 A;  3PSN A;  4J6O A;  4O5G A;  4H2I A;  4O4K A;  2HYO A;  4HD0 A;  4DSY A;  3IB7 A;  5HPE A;  3EGH A;  3IVE A;  2QFR A;  3QG5 C;  3QFO A;  4IYP C;  1OIE A;  2NPP C;  1S3M A;  3DW8 C;  4G9J A;  3H69 A;  3H64 A;  2IAE C;  3K7W C;  4LAC C;  5C1V A;  3C5W C;  3EGG A;  5J28 A;  2BCD A;  4O43 A;  2O8A A;  3H62 B;  3P71 C;  2QFP A;  3HVQ A;  4TUI A;  2NXF A;  4OR9 A;  2NYL C;  2WDF A;  2ZBM A;  3QFN A;  4I5N C;  4F0Z A;  3IVD A;  4UWQ A;  3C9F A;  1W24 A;  4B2O A;  3QFK A;  2Z06 A;  4H1S A;  3LL8 A;  3AV0 A;  3RL4 A;  1M63 A;  4LU9 A;  4FBK A;  4V0X A;  3E7A A;  4YKE A;  4MP0 A;  2IE3 C;  4H2F A;  1TCO A;  4MOV A;  5B8I A;  4FBQ A;  4H1Y P;  4FCX A;  3RL3 A;  3ICF A;  1T70 A;  1S95 A;  2Z1A A;  1HPU A;  4MOY A;  2USH A;  1U32 A;  1QFC A;  3DSC A;  2HY1 A;  3TGH A;  1IT6 A;  4ORB A;  4XPN A;  5GTU A;  1OI8 A;  4V0W A;  2IE4 C;  5IOH A;  3E7B A;  1G5B A;  4NZV A;  1JK7 A;  3ZTV A;  1QHW A;  2GJU A;  3AUZ A;  1SU1 A;  2KKN A;  3H63 A;  2R17 A;  1S3L A;  1NNW A;  1KBP A;  5JPE A;  5F3W A;  5JPF A;  2BQ8 X;  4LTY A;  4Q7F A;  3ZU0 A;  5EQV A;  1UTE A;  3IB8 A;  4DT2 A;  3V4Y A;  2AHD A;  2WDC A;  2WDD A;  5DNY A;  1Z2W A;  2WDE A;  1V73 A;  4DHL A;  3H61 A;  3JYF A;  4UT2 A;  4UT3 B;  4KBP A;  5INB A;  3N5U A;  4M0V A;  2HYP A;  4ZX2 A;  1UF3 A;  2JOG A;  4JA9 A;  1XM7 A; 
#chains in the Genus database with same CATH topology
 1XZW A;  3RL5 A;  4ORA A;  3RQZ A;  4KKZ A;  1S3N A;  4JA7 A;  1T71 A;  4V0V A;  3H60 A;  4O24 A;  2P6B A;  3H68 A;  2DFJ A;  3KBP A;  2CV9 A;  1HP1 A;  2BDX A;  3DSD A;  1OID A;  2Q8U A;  4H2B A;  1Z2X A;  4H2G A;  3QFM A;  1II7 A;  5JJT A;  3K7V C;  4TUG A;  4FBW A;  4WWL A;  2YVT A;  3T1I A;  2O8G A;  4I5L C;  3PSO A;  2A22 A;  3CK2 A;  3H67 A;  1AUI A;  1WAO 1;  2Z72 A;  3H66 A;  2XMO A;  3THO B;  2NYM C;  3FGA C;  4ZVZ A;  1USH A;  1WAR A;  1S8E A;  1MF8 A;  1S70 A;  2QJC A;  1FJM A;  3GVE A;  4IL1 A;  3THN A;  4ORC A;  1HO5 A;  4UT3 A;  3PSN A;  4J6O A;  4O5G A;  4H2I A;  4O4K A;  2HYO A;  4HD0 A;  4DSY A;  3IB7 A;  5HPE A;  3EGH A;  3IVE A;  2QFR A;  3QG5 C;  3QFO A;  4IYP C;  1OIE A;  2NPP C;  1S3M A;  3DW8 C;  4G9J A;  3H69 A;  3H64 A;  3FLO A;  2IAE C;  3K7W C;  4LAC C;  5C1V A;  3C5W C;  3EGG A;  5J28 A;  2DXN A;  2BCD A;  2DXL A;  2YEQ A;  4O43 A;  2O8A A;  3H62 B;  3P71 C;  2QFP A;  3HVQ A;  4TUI A;  2NXF A;  4OR9 A;  2NYL C;  2WDF A;  2ZBM A;  2ZOA A;  3QFN A;  4I5N C;  4F0Z A;  3IVD A;  4UWQ A;  3C9F A;  1W24 A;  4B2O A;  3QFK A;  2Z06 A;  4H1S A;  3LL8 A;  3AV0 A;  3RL4 A;  1M63 A;  4LU9 A;  4FBK A;  4V0X A;  3E7A A;  4YKE A;  4MP0 A;  2IE3 C;  4H2F A;  1TCO A;  4MOV A;  5B8I A;  4FBQ A;  4H1Y P;  4FCX A;  3RL3 A;  3ICF A;  1T70 A;  1S95 A;  2Z1A A;  1HPU A;  4MOY A;  2USH A;  1U32 A;  1QFC A;  3DSC A;  2HY1 A;  3TGH A;  3D03 A;  1IT6 A;  4ORB A;  4XPN A;  5GTU A;  1OI8 A;  4V0W A;  2IE4 C;  5IOH A;  3E7B A;  1G5B A;  4NZV A;  1JK7 A;  3ZTV A;  1QHW A;  2GJU A;  3AUZ A;  1SU1 A;  2KKN A;  3H63 A;  2R17 A;  1S3L A;  1NNW A;  1KBP A;  5JPE A;  5F3W A;  5JPF A;  2BQ8 X;  4LTY A;  4Q7F A;  3ZU0 A;  5EQV A;  1UTE A;  3IB8 A;  4DT2 A;  3V4Y A;  2AHD A;  3E0J A;  2WDC A;  2WDD A;  5DNY A;  1Z2W A;  2WDE A;  1V73 A;  4DHL A;  3H61 A;  3JYF A;  4UT2 A;  4UT3 B;  4KBP A;  5INB A;  3N5U A;  4M0V A;  2HYP A;  2ZO9 B;  4ZX2 A;  1UF3 A;  2JOG A;  4JA9 A;  1XM7 A; 
#chains in the Genus database with same CATH homology
 1XZW A;  3RL5 A;  4ORA A;  3RQZ A;  4KKZ A;  1S3N A;  4JA7 A;  1T71 A;  4V0V A;  3H60 A;  4O24 A;  2P6B A;  3H68 A;  2DFJ A;  3KBP A;  2CV9 A;  1HP1 A;  2BDX A;  3DSD A;  1OID A;  2Q8U A;  4H2B A;  1Z2X A;  4H2G A;  3QFM A;  1II7 A;  5JJT A;  3K7V C;  4TUG A;  4FBW A;  4WWL A;  2YVT A;  3T1I A;  2O8G A;  4I5L C;  3PSO A;  2A22 A;  3CK2 A;  3H67 A;  1AUI A;  1WAO 1;  2Z72 A;  3H66 A;  2XMO A;  3THO B;  2NYM C;  3FGA C;  4ZVZ A;  1USH A;  1WAR A;  1S8E A;  1MF8 A;  1S70 A;  2QJC A;  1FJM A;  3GVE A;  4IL1 A;  3THN A;  4ORC A;  1HO5 A;  4UT3 A;  3PSN A;  4J6O A;  4O5G A;  4H2I A;  4O4K A;  2HYO A;  4HD0 A;  4DSY A;  3IB7 A;  5HPE A;  3EGH A;  3IVE A;  2QFR A;  3QG5 C;  3QFO A;  4IYP C;  1OIE A;  2NPP C;  1S3M A;  3DW8 C;  4G9J A;  3H69 A;  3H64 A;  3FLO A;  2IAE C;  3K7W C;  4LAC C;  5C1V A;  3C5W C;  3EGG A;  5J28 A;  2DXN A;  2BCD A;  2DXL A;  2YEQ A;  4O43 A;  2O8A A;  3H62 B;  3P71 C;  2QFP A;  3HVQ A;  4TUI A;  2NXF A;  4OR9 A;  2NYL C;  2WDF A;  2ZBM A;  2ZOA A;  3QFN A;  4I5N C;  4F0Z A;  3IVD A;  4UWQ A;  3C9F A;  1W24 A;  4B2O A;  3QFK A;  2Z06 A;  4H1S A;  3LL8 A;  3AV0 A;  3RL4 A;  1M63 A;  4LU9 A;  4FBK A;  4V0X A;  3E7A A;  4YKE A;  4MP0 A;  2IE3 C;  4H2F A;  1TCO A;  4MOV A;  5B8I A;  4FBQ A;  4H1Y P;  4FCX A;  3RL3 A;  3ICF A;  1T70 A;  1S95 A;  2Z1A A;  1HPU A;  4MOY A;  2USH A;  1U32 A;  1QFC A;  3DSC A;  2HY1 A;  3TGH A;  3D03 A;  1IT6 A;  4ORB A;  4XPN A;  5GTU A;  1OI8 A;  4V0W A;  2IE4 C;  5IOH A;  3E7B A;  1G5B A;  4NZV A;  1JK7 A;  3ZTV A;  1QHW A;  2GJU A;  3AUZ A;  1SU1 A;  2KKN A;  3H63 A;  2R17 A;  1S3L A;  1NNW A;  1KBP A;  5JPE A;  5F3W A;  5JPF A;  2BQ8 X;  4LTY A;  4Q7F A;  3ZU0 A;  5EQV A;  1UTE A;  3IB8 A;  4DT2 A;  3V4Y A;  2AHD A;  3E0J A;  2WDC A;  2WDD A;  5DNY A;  1Z2W A;  2WDE A;  1V73 A;  4DHL A;  3H61 A;  3JYF A;  4UT2 A;  4UT3 B;  4KBP A;  5INB A;  3N5U A;  4M0V A;  2HYP A;  2ZO9 B;  4ZX2 A;  1UF3 A;  2JOG A;  4JA9 A;  1XM7 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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