4A3KL

Rna polymerase ii initial transcribing complex with a 7nt dna-rna hybrid
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Initial RNA Polymerase II Transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4a3kL00
2R93L 4A3LL 1I6HL 2E2JL 3S1QL 3FKIL 3GTKL 4C2M1 3GTML 2NVXL 3GTLL 4A93L 4A3DL 3PO3L 3K7AL 3GTOL 3S17L 2YU9L 1TWAL 2B63L 5C4JL 3M4OL 4A3GL 4C3HL 5M3ML 3HOVL 2R92L 3S15L 5M5YL 4A3ML 1SFOL 5C4XL 3S14L 4A3JL 4QIWP 3GTJL 2JA8L 4X6AL 1TWGL 4BXXL 3HOWL 5IYCL 4Y7NL 4BY1L 5IYDL 3S16L 5IYBL 3S2HL 5IP9L 2JA6L 1Y1VL 1R9TL 3H0GL 2JA5L 3M3YL 3S1NL 3GTQL 3HOZL 1K83L 5FJ8L 3HKZP 3S1ML 4A3KL 2WAQP 3PO2L 4Y52L 5M3FL 2R7ZL 4BBRL 4C3JL 5M5WL 3HOXL 2E2IL 1I50L 4A3FL 5M5XL 5IP7L 4A3BL 2E2HL 3HOUL 1I3QL 1TWFL 2WB1P 2PMZP 3S2DL 4A3IL 3RZOL 2Y0SP 3HOYL 1WCML 2NVYL 3I4NL 1TWCL 2NVTL 5C3EL 5C44L 3GTGL 2VUML 4C3IL 2NVQL 3GTPL 3S1RL 5FLML 4AYBP 3H3VM 4BBSL 1TWHL 4BY7L 1Y1WL 3I4ML 4A3CL 2JA7L 4A3EL 3CQZL 3RZDL
chains in the Genus database with same CATH superfamily
4YWMA 2R93L 2CKAA 1NNQA 4C2M1 1IU5A 4A3DL 1PZXA 3PO3L 4TVMA 2PVEA 2KKDA 3GTOL 1R0JA 3MPSA 1NXGA 3H97A 1RDGA 2GMGA 2B63L 3HJYB 5GAEc 3NFPI 2J9UB 1PFWA 4A3GL 4C3HL 1C09A 4G6BA 5M3ML 3HOVL 2R92L 5RXNA 5M5YL 3LWQB 2O5JD 3HJWB 1IU6A 1CADA 4BXXL 1B71A 2XJTA 5IYCL 2JI2A 1VCXA 1PFUA 1R9TL 4AR6A 1K83L 4AI3A 4A3KL 1B13A 4POGA 3J7Z1 4C3JL 1R0HA 5M5WL 1T9PA 1VZGA 4A3FL 5AI3A 3VPBE 5IP7L 2ZIXA 2E2HL 4AI1A 1LKMA 2PMZP 5JVH1 4K9FA 4AHXA 2Y0SP 2NVYL 1TWCL 2NVTL 5C3EL 1RB9A 3H99A 1LKOA 1F4LA 3B08B 4U671 2MS3A 3J7Y1 2HR5A 5FLML 2JI3A 5MGNA 2AUSB 2XJRA 2XJVA 1ODHA 5AI2A 2E2JL 3S1QL 3FKIL 4UY81 2NVXL 3GTLL 2M6PA 4AI0A 5AN9H 4AHYA 1BRFA 2YU9L 5C4JL 1ZRPA 3PIO1 3RZTA 1P7PA 1SFOL 4YWLA 4A3JL 1TWGL 2C6AA 3PWFA 3WWNB 2L0ZA 1BQ9A 3SS2A 1IRNA 2C6BA 3S16L 2XJUA 1E8JA 5IYBL 2EY4E 4XXBB 2JA6L 4E6YA 3LNLA 2JA5L 3M3YL 1YV1A 3HOZL 5FJ8L 5DM61 3HKZP 1DX8A 1IW7D 3PO2L 4ME3A 2VL6A 2H12A 4ZN3B 2PVXA 1QCVA 3PZAA 4Y52L 5M3FL 3B0AB 3RYGA 2E2IL 1FHMA 4AHZA 1R0IA 1BQ8A 1B2JA 4GS7D 1NXEA 2PSMC 3HOUL 3QQCE 1YK4A 5GADc 2ERSA 1WJVA 4JAGA 1VZHA 2KN9A 5C44L 3GTGL 2LCQA 1R0GA 2M4VA 1S2ZA 2BE5D 4C3IL 1RDVA 3H3VM 4BY7L 4A3EL 3RZDL 5MF6A 3PKJA 4A3LL 1I6HL 1CAAA 3PIP1 3LWRB 5MLC3 2V0EA 2ERJA 5EIOC 1TWAL 1RWDA 3M4OL 2Z3QB 3MQKB 1T9QA 2XJSA 3FDJA 3S15L 2AQCA 3ZG6A 3GTJL 4X6AL 3PL5A 1BE7A 4AHWA 1BFYA 3P8BA 3HOWL 4BY1L 2APOB 5IYDL 5MFPA 1S30A 1OWCA 2CR8A 3S2HL 1FHHA 1Y1VL 3P2AA 3GTQL 2AYJA 2B5ID 3RZ6A 2M4YA 5GAHc 3S1ML 3JR7A 1DVBA 2NYDA 3KYVA 4AR4A 3HOXL 1I50L 5M5XL 5H1Sc 3LWPB 8RXNA 1I3QL 1TWFL 1R0FA 2WB1P 2XJPA 4A3IL 1YUXA 3LWOB 2CKCA 3RZOL 2XJQA 1WCML 4TPUA 3I4NL 2V0FA 3KYXA 6RXNA 1VZIA 2VUML 3GTPL 5EINC 3H9BA 4AR3A 4AI2A 4A3CL 1LKPA 4XGHA 2RFKB 3A44A 1RYTA 5JVG1 4POFA 1RYQA 3KYWA 5DM71 3GTKL 3GTML 1H7VA 2JI1A 3K35A 4A93L 3K7AL 3S17L 3LWVB 2QL0A 3KYUA 1QQTA 1SMMA 1JYBA 3MSUA 3IU3I 1SMUA 1SMWA 1S24A 1YUZA 5GAGc 2K2DA 4A3ML 5IY0A 5C4XL 3S14L 2Z3RB 1YK5A 4QIWP 2JA8L 2M6OA 4Y7NL 1PFVA 4JADA 3PKIA 2PPTA 5IP9L 4JAEA 1PFYA 3H9CA 2DSXA 3H0GL 3S1NL 5MFZA 1OWBA 2WAQP 2R7ZL 4BBRL 2RDVA 2V3BB 4LHNA 1B2OA 4AR5A 4A3BL 2A6ED 4RXNA 4JAFA 2HVYC 3S2DL 1QYBA 7RXNA 1Z92B 3KYYA 3LPEB 3HOYL 5K2ME 4WFN1 1LTLA 4ZN1B 4V196 3QVDA 2PYAA 2A68D 2NVQL 4B8CD 4LHLA 3S1RL 2A69D 4AYBP 4BBSL 3HAXC 1IROA 1TWHL 3WWLA 1Y1WL 3I4ML 1T9OA 2A6HD 2JA7L 3CQZL
chains in the Genus database with same CATH topology
2R93L 4A3LL 1I6HL 2E2JL 3S1QL 3FKIL 3GTKL 4C2M1 3GTML 2NVXL 3GTLL 4A93L 4A3DL 3PO3L 3K7AL 3GTOL 3S17L 2YU9L 1TWAL 2B63L 5C4JL 3M4OL 4A3GL 4C3HL 5M3ML 3HOVL 2R92L 3S15L 5M5YL 4A3ML 1SFOL 5C4XL 3S14L 4A3JL 4QIWP 3GTJL 2JA8L 4X6AL 1TWGL 4BXXL 3HOWL 5IYCL 4Y7NL 4BY1L 5IYDL 3S16L 5IYBL 3S2HL 5IP9L 2JA6L 1Y1VL 1R9TL 3H0GL 2JA5L 3M3YL 3S1NL 3GTQL 3HOZL 1K83L 5FJ8L 3HKZP 3S1ML 4A3KL 2WAQP 3PO2L 4Y52L 5M3FL 2R7ZL 4BBRL 4C3JL 5M5WL 3HOXL 2E2IL 1I50L 4A3FL 5M5XL 5IP7L 4A3BL 2E2HL 3HOUL 1I3QL 1TWFL 2WB1P 2PMZP 3S2DL 4A3IL 3RZOL 2Y0SP 3HOYL 1WCML 2NVYL 3I4NL 1TWCL 2NVTL 5C3EL 5C44L 3GTGL 2VUML 4C3IL 2NVQL 3GTPL 3S1RL 5FLML 4AYBP 3H3VM 4BBSL 1TWHL 4BY7L 1Y1WL 3I4ML 4A3CL 2JA7L 4A3EL 3CQZL 3RZDL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R93 L;  4A3L L;  1I6H L;  2E2J L;  3S1Q L;  3FKI L;  3GTK L;  4C2M 1;  3GTM L;  2NVX L;  3GTL L;  4A93 L;  4A3D L;  3PO3 L;  3K7A L;  3GTO L;  3S17 L;  2YU9 L;  1TWA L;  2B63 L;  5C4J L;  3M4O L;  4A3G L;  4C3H L;  5M3M L;  3HOV L;  2R92 L;  3S15 L;  5M5Y L;  4A3M L;  1SFO L;  5C4X L;  3S14 L;  4A3J L;  4QIW P;  3GTJ L;  2JA8 L;  4X6A L;  1TWG L;  4BXX L;  3HOW L;  5IYC L;  4Y7N L;  4BY1 L;  5IYD L;  3S16 L;  5IYB L;  3S2H L;  5IP9 L;  2JA6 L;  1Y1V L;  1R9T L;  3H0G L;  2JA5 L;  3M3Y L;  3S1N L;  3GTQ L;  3HOZ L;  1K83 L;  5FJ8 L;  3HKZ P;  3S1M L;  4A3K L;  2WAQ P;  3PO2 L;  4Y52 L;  5M3F L;  2R7Z L;  4BBR L;  4C3J L;  5M5W L;  3HOX L;  2E2I L;  1I50 L;  4A3F L;  5M5X L;  5IP7 L;  4A3B L;  2E2H L;  3HOU L;  1I3Q L;  1TWF L;  2WB1 P;  2PMZ P;  3S2D L;  4A3I L;  3RZO L;  2Y0S P;  3HOY L;  1WCM L;  2NVY L;  3I4N L;  1TWC L;  2NVT L;  5C3E L;  5C44 L;  3GTG L;  2VUM L;  4C3I L;  2NVQ L;  3GTP L;  3S1R L;  5FLM L;  4AYB P;  3H3V M;  4BBS L;  1TWH L;  4BY7 L;  1Y1W L;  3I4M L;  4A3C L;  2JA7 L;  4A3E L;  3CQZ L;  3RZD L; 
#chains in the Genus database with same CATH topology
 4YWM A;  2R93 L;  2CKA A;  1NNQ A;  4C2M 1;  1IU5 A;  4A3D L;  1PZX A;  3PO3 L;  4TVM A;  2PVE A;  2KKD A;  3GTO L;  1R0J A;  3MPS A;  1NXG A;  3H97 A;  1RDG A;  2GMG A;  2B63 L;  3HJY B;  5GAE c;  3NFP I;  2J9U B;  1PFW A;  4A3G L;  4C3H L;  1C09 A;  4G6B A;  5M3M L;  3HOV L;  2R92 L;  5RXN A;  5M5Y L;  3LWQ B;  2O5J D;  3HJW B;  1IU6 A;  1CAD A;  4BXX L;  1B71 A;  2XJT A;  5IYC L;  2JI2 A;  1VCX A;  1PFU A;  1R9T L;  4AR6 A;  1K83 L;  4AI3 A;  4A3K L;  1B13 A;  4POG A;  3J7Z 1;  4C3J L;  1R0H A;  5M5W L;  1T9P A;  1VZG A;  4A3F L;  5AI3 A;  3VPB E;  5IP7 L;  2ZIX A;  2E2H L;  4AI1 A;  1LKM A;  2PMZ P;  5JVH 1;  4K9F A;  4AHX A;  2Y0S P;  2NVY L;  1TWC L;  2NVT L;  5C3E L;  1RB9 A;  3H99 A;  1LKO A;  1F4L A;  3B08 B;  4U67 1;  2MS3 A;  3J7Y 1;  2HR5 A;  5FLM L;  2JI3 A;  5MGN A;  2AUS B;  2XJR A;  2XJV A;  1ODH A;  5AI2 A;  2E2J L;  3S1Q L;  3FKI L;  4UY8 1;  2NVX L;  3GTL L;  2M6P A;  4AI0 A;  5AN9 H;  4AHY A;  1BRF A;  2YU9 L;  5C4J L;  1ZRP A;  3PIO 1;  3RZT A;  1P7P A;  1SFO L;  4YWL A;  4A3J L;  1TWG L;  2C6A A;  3PWF A;  3WWN B;  2L0Z A;  1BQ9 A;  3SS2 A;  1IRN A;  2C6B A;  3S16 L;  2XJU A;  1E8J A;  5IYB L;  2EY4 E;  4XXB B;  2JA6 L;  4E6Y A;  3LNL A;  2JA5 L;  3M3Y L;  1YV1 A;  3HOZ L;  5FJ8 L;  5DM6 1;  3HKZ P;  1DX8 A;  1IW7 D;  3PO2 L;  4ME3 A;  2VL6 A;  2H12 A;  4ZN3 B;  2PVX A;  1QCV A;  3PZA A;  4Y52 L;  5M3F L;  3B0A B;  3RYG A;  2E2I L;  1FHM A;  4AHZ A;  1R0I A;  1BQ8 A;  1B2J A;  4GS7 D;  1NXE A;  2PSM C;  3HOU L;  3QQC E;  1YK4 A;  5GAD c;  2ERS A;  1WJV A;  4JAG A;  1VZH A;  2KN9 A;  5C44 L;  3GTG L;  2LCQ A;  1R0G A;  2M4V A;  1S2Z A;  2BE5 D;  4C3I L;  1RDV A;  3H3V M;  4BY7 L;  4A3E L;  3RZD L;  5MF6 A;  3PKJ A;  4A3L L;  1I6H L;  1CAA A;  3PIP 1;  3LWR B;  5MLC 3;  2V0E A;  2ERJ A;  5EIO C;  1TWA L;  1RWD A;  3M4O L;  2Z3Q B;  3MQK B;  1T9Q A;  2XJS A;  3FDJ A;  3S15 L;  2AQC A;  3ZG6 A;  3GTJ L;  4X6A L;  3PL5 A;  1BE7 A;  4AHW A;  1BFY A;  3P8B A;  3HOW L;  4BY1 L;  2APO B;  5IYD L;  5MFP A;  1S30 A;  1OWC A;  2CR8 A;  3S2H L;  1FHH A;  1Y1V L;  3P2A A;  3GTQ L;  2AYJ A;  2B5I D;  3RZ6 A;  2M4Y A;  5GAH c;  3S1M L;  3JR7 A;  1DVB A;  2NYD A;  3KYV A;  4AR4 A;  3HOX L;  1I50 L;  5M5X L;  5H1S c;  3LWP B;  8RXN A;  1I3Q L;  1TWF L;  1R0F A;  2WB1 P;  2XJP A;  4A3I L;  1YUX A;  3LWO B;  2CKC A;  3RZO L;  2XJQ A;  1WCM L;  4TPU A;  3I4N L;  2V0F A;  3KYX A;  6RXN A;  1VZI A;  2VUM L;  3GTP L;  5EIN C;  3H9B A;  4AR3 A;  4AI2 A;  4A3C L;  1LKP A;  4XGH A;  2RFK B;  3A44 A;  1RYT A;  5JVG 1;  4POF A;  1RYQ A;  3KYW A;  5DM7 1;  3GTK L;  3GTM L;  1H7V A;  2JI1 A;  3K35 A;  4A93 L;  3K7A L;  3S17 L;  3LWV B;  2QL0 A;  3KYU A;  1QQT A;  1SMM A;  1JYB A;  3MSU A;  3IU3 I;  1SMU A;  1SMW A;  1S24 A;  1YUZ A;  5GAG c;  2K2D A;  4A3M L;  5IY0 A;  5C4X L;  3S14 L;  2Z3R B;  1YK5 A;  4QIW P;  2JA8 L;  2M6O A;  4Y7N L;  1PFV A;  4JAD A;  3PKI A;  2PPT A;  5IP9 L;  4JAE A;  1PFY A;  3H9C A;  2DSX A;  3H0G L;  3S1N L;  5MFZ A;  1OWB A;  2WAQ P;  2R7Z L;  4BBR L;  2RDV A;  2V3B B;  4LHN A;  1B2O A;  4AR5 A;  4A3B L;  2A6E D;  4RXN A;  4JAF A;  2HVY C;  3S2D L;  1QYB A;  7RXN A;  1Z92 B;  3KYY A;  3LPE B;  3HOY L;  5K2M E;  4WFN 1;  1LTL A;  4ZN1 B;  4V19 6;  3QVD A;  2PYA A;  2A68 D;  2NVQ L;  4B8C D;  4LHL A;  3S1R L;  2A69 D;  4AYB P;  4BBS L;  3HAX C;  1IRO A;  1TWH L;  3WWL A;  1Y1W L;  3I4M L;  1T9O A;  2A6H D;  2JA7 L;  3CQZ L; 
#chains in the Genus database with same CATH homology
 2R93 L;  4A3L L;  1I6H L;  2E2J L;  3S1Q L;  3FKI L;  3GTK L;  4C2M 1;  3GTM L;  2NVX L;  3GTL L;  4A93 L;  4A3D L;  3PO3 L;  3K7A L;  3GTO L;  3S17 L;  2YU9 L;  1TWA L;  2B63 L;  5C4J L;  3M4O L;  4A3G L;  4C3H L;  5M3M L;  3HOV L;  2R92 L;  3S15 L;  5M5Y L;  4A3M L;  1SFO L;  5C4X L;  3S14 L;  4A3J L;  4QIW P;  3GTJ L;  2JA8 L;  4X6A L;  1TWG L;  4BXX L;  3HOW L;  5IYC L;  4Y7N L;  4BY1 L;  5IYD L;  3S16 L;  5IYB L;  3S2H L;  5IP9 L;  2JA6 L;  1Y1V L;  1R9T L;  3H0G L;  2JA5 L;  3M3Y L;  3S1N L;  3GTQ L;  3HOZ L;  1K83 L;  5FJ8 L;  3HKZ P;  3S1M L;  4A3K L;  2WAQ P;  3PO2 L;  4Y52 L;  5M3F L;  2R7Z L;  4BBR L;  4C3J L;  5M5W L;  3HOX L;  2E2I L;  1I50 L;  4A3F L;  5M5X L;  5IP7 L;  4A3B L;  2E2H L;  3HOU L;  1I3Q L;  1TWF L;  2WB1 P;  2PMZ P;  3S2D L;  4A3I L;  3RZO L;  2Y0S P;  3HOY L;  1WCM L;  2NVY L;  3I4N L;  1TWC L;  2NVT L;  5C3E L;  5C44 L;  3GTG L;  2VUM L;  4C3I L;  2NVQ L;  3GTP L;  3S1R L;  5FLM L;  4AYB P;  3H3V M;  4BBS L;  1TWH L;  4BY7 L;  1Y1W L;  3I4M L;  4A3C L;  2JA7 L;  4A3E L;  3CQZ L;  3RZD L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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