4V0VA

The crystal structure of mouse pp1g in complex with truncated human ppp1r15b (631-660)
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
295
structure length
295
Chain Sequence
MLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase regulator
source organism Mus musculus
molecule keywords SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUB
total genus 110
structure length 295
sequence length 295
chains with identical sequence C
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2014-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 4v0vA00
3C9FA 4ORAA 4TUGA 1TCOA 4DSYA 3TGHA 4OR9A 4JA9A 1W24A 3CK2A 2JOGA 4TUIA 2KKNA 3ZTVA 3H62B 1S3NA 2AHDA 4KBPA 4J6OA 3PSNA 5EQVA 4UT3A 4LU9A 4NZVA 2QFRA 4ORCA 1XZWA 3P71C 4FCXA 3ICFA 3RL3A 4DT2A 2GJUA 2IE3C 4FBQA 3QG5C 3H67A 3QFMA 4IL1A 2Z1AA 4I5LC 3QFNA 1XM7A 2WDFA 4G9JA 1S70A 1WAO1 3KBPA 4UWQA 2NPPC 2IE4C 3AUZA 5F3WA 1JK7A 3RL5A 3THOB 4FBKA 2NYMC 4WWLA 3N5UA 3HVQA 3ZU0A 1OI8A 4H2IA 3RL4A 1WARA 1OIDA 3AV0A 3T1IA 2Z06A 1UF3A 3IVDA 1SU1A 4ORBA 1HO5A 5B8IA 3JYFA 4MP0A 1S3LA 2QJCA 2BQ8X 2WDCA 3H63A 1T71A 2Z72A 3C5WC 5JPEA 1S3MA 3K7VC 2NXFA 3K7WC 1II7A 4ZX2A 2DFJA 1MF8A 5JPFA 4O5GA 4UT2A 3H60A 1AUIA 4UT3B 3PSOA 5C1VA 2WDEA 2USHA 4Q7FA 4ZVZA 1HP1A 3E7BA 3IB7A 1IT6A 4H2GA 1NNWA 4V0XA 2CV9A 3IVEA 5J28A 4IYPC 3H66A 2NYLC 2A22A 4V0VA 4H2BA 3THNA 3IB8A 4FBWA 2R17A 3EGHA 3GVEA 3DSDA 2O8GA 1Z2WA 5JJTA 4M0VA 3H61A 4V0WA 1FJMA 2QFPA 1V73A 3EGGA 1U32A 4B2OA 5DNYA 4H2FA 4H1SA 2BDXA 4I5NC 2Q8UA 4O4KA 4H1YP 1HPUA 1T70A 2BCDA 3V4YA 4MOYA 2HY1A 2HYPA 1KBPA 1M63A 4XPNA 3H64A 4O24A 2O8AA 2IAEC 3DSCA 3DW8C 1S95A 2P6BA 4HD0A 4F0ZA 3H69A 1QFCA 4JA7A 4LACC 1QHWA 1G5BA 4MOVA 3LL8A 4YKEA 1UTEA 3E7AA 3H68A 2YVTA 4LTYA 3RQZA 2WDDA 2HYOA 4O43A 5HPEA 1Z2XA 1S8EA 5INBA 5GTUA 3QFKA 1USHA 1OIEA 3FGAC 3QFOA 2ZBMA 5IOHA 4KKZA 2XMOA 4DHLA
chains in the Genus database with same CATH superfamily
3C9FA 3D03A 4ORAA 4TUGA 1TCOA 4DSYA 3TGHA 4OR9A 4JA9A 1W24A 3CK2A 2JOGA 3FLOA 4TUIA 2KKNA 3ZTVA 3H62B 1S3NA 2AHDA 4KBPA 4J6OA 3PSNA 5EQVA 4UT3A 4LU9A 4NZVA 2QFRA 2YEQA 1XZWA 3P71C 4FCXA 3ICFA 4ORCA 3RL3A 4DT2A 2GJUA 2ZOAA 2IE3C 4FBQA 3QG5C 3H67A 3QFMA 4IL1A 2Z1AA 4I5LC 3QFNA 1XM7A 2WDFA 4G9JA 1S70A 1WAO1 3KBPA 4UWQA 2NPPC 2IE4C 3AUZA 5F3WA 1JK7A 3RL5A 3THOB 4FBKA 2NYMC 4WWLA 3N5UA 3HVQA 3ZU0A 1OI8A 4H2IA 3RL4A 1WARA 1OIDA 3AV0A 3T1IA 2Z06A 1UF3A 3IVDA 1SU1A 4ORBA 1HO5A 5B8IA 3JYFA 4MP0A 3E0JA 1S3LA 2QJCA 2BQ8X 2WDCA 3H63A 1T71A 2Z72A 3C5WC 5JPEA 1S3MA 3K7VC 2NXFA 3K7WC 1II7A 4ZX2A 2DFJA 1MF8A 5JPFA 4O5GA 4UT2A 3H60A 1AUIA 4UT3B 3PSOA 5C1VA 2WDEA 2USHA 4Q7FA 4ZVZA 2DXNA 1HP1A 3E7BA 3IB7A 1IT6A 4H2GA 1NNWA 4V0XA 2CV9A 3IVEA 5J28A 4IYPC 3H66A 2NYLC 2A22A 4V0VA 4H2BA 3THNA 3IB8A 4FBWA 2R17A 3EGHA 3GVEA 3DSDA 2O8GA 1Z2WA 5JJTA 4M0VA 3H61A 4V0WA 1FJMA 2QFPA 1V73A 3EGGA 1U32A 4B2OA 5DNYA 4H2FA 2DXLA 4H1SA 2BDXA 4I5NC 2Q8UA 4O4KA 4H1YP 1HPUA 1T70A 2BCDA 3V4YA 4MOYA 2HY1A 2HYPA 1KBPA 1M63A 4XPNA 3H64A 4O24A 2O8AA 2IAEC 3DSCA 3DW8C 1S95A 2P6BA 4HD0A 4F0ZA 3H69A 1QFCA 4JA7A 4LACC 1QHWA 1G5BA 4MOVA 3LL8A 4YKEA 1UTEA 3E7AA 3H68A 2YVTA 4LTYA 2ZO9B 3RQZA 2WDDA 2HYOA 4O43A 5HPEA 1Z2XA 1S8EA 5INBA 5GTUA 3QFKA 1USHA 1OIEA 3FGAC 3QFOA 2ZBMA 5IOHA 4KKZA 2XMOA 4DHLA
chains in the Genus database with same CATH topology
3C9FA 3D03A 4ORAA 4TUGA 1TCOA 4DSYA 3TGHA 4OR9A 4JA9A 1W24A 3CK2A 2JOGA 3FLOA 4TUIA 2KKNA 3ZTVA 3H62B 1S3NA 2AHDA 4KBPA 4J6OA 3PSNA 5EQVA 4UT3A 4LU9A 4NZVA 2QFRA 2YEQA 1XZWA 3P71C 4FCXA 3ICFA 4ORCA 3RL3A 4DT2A 2GJUA 2ZOAA 2IE3C 4FBQA 3QG5C 3H67A 3QFMA 4IL1A 2Z1AA 4I5LC 3QFNA 1XM7A 2WDFA 4G9JA 1S70A 1WAO1 3KBPA 4UWQA 2NPPC 2IE4C 3AUZA 5F3WA 1JK7A 3RL5A 3THOB 4FBKA 2NYMC 4WWLA 3N5UA 3HVQA 3ZU0A 1OI8A 4H2IA 3RL4A 1WARA 1OIDA 3AV0A 3T1IA 2Z06A 1UF3A 3IVDA 1SU1A 4ORBA 1HO5A 5B8IA 3JYFA 4MP0A 3E0JA 1S3LA 2QJCA 2BQ8X 2WDCA 3H63A 1T71A 2Z72A 3C5WC 5JPEA 1S3MA 3K7VC 2NXFA 3K7WC 1II7A 4ZX2A 2DFJA 1MF8A 5JPFA 4O5GA 4UT2A 3H60A 1AUIA 4UT3B 3PSOA 5C1VA 2WDEA 2USHA 4Q7FA 4ZVZA 2DXNA 1HP1A 3E7BA 3IB7A 1IT6A 4H2GA 1NNWA 4V0XA 2CV9A 3IVEA 5J28A 4IYPC 3H66A 2NYLC 2A22A 4V0VA 4H2BA 3THNA 3IB8A 4FBWA 2R17A 3EGHA 3GVEA 3DSDA 2O8GA 1Z2WA 5JJTA 4M0VA 3H61A 4V0WA 1FJMA 2QFPA 1V73A 3EGGA 1U32A 4B2OA 5DNYA 4H2FA 2DXLA 4H1SA 2BDXA 4I5NC 2Q8UA 4O4KA 4H1YP 1HPUA 1T70A 2BCDA 3V4YA 4MOYA 2HY1A 2HYPA 1KBPA 1M63A 4XPNA 3H64A 4O24A 2O8AA 2IAEC 3DSCA 3DW8C 1S95A 2P6BA 4HD0A 4F0ZA 3H69A 1QFCA 4JA7A 4LACC 1QHWA 1G5BA 4MOVA 3LL8A 4YKEA 1UTEA 3E7AA 3H68A 2YVTA 4LTYA 2ZO9B 3RQZA 2WDDA 2HYOA 4O43A 5HPEA 1Z2XA 1S8EA 5INBA 5GTUA 3QFKA 1USHA 1OIEA 3FGAC 3QFOA 2ZBMA 5IOHA 4KKZA 2XMOA 4DHLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C9F A;  4ORA A;  4TUG A;  1TCO A;  4DSY A;  3TGH A;  4OR9 A;  4JA9 A;  1W24 A;  3CK2 A;  2JOG A;  4TUI A;  2KKN A;  3ZTV A;  3H62 B;  1S3N A;  2AHD A;  4KBP A;  4J6O A;  3PSN A;  5EQV A;  4UT3 A;  4LU9 A;  4NZV A;  2QFR A;  4ORC A;  1XZW A;  3P71 C;  4FCX A;  3ICF A;  3RL3 A;  4DT2 A;  2GJU A;  2IE3 C;  4FBQ A;  3QG5 C;  3H67 A;  3QFM A;  4IL1 A;  2Z1A A;  4I5L C;  3QFN A;  1XM7 A;  2WDF A;  4G9J A;  1S70 A;  1WAO 1;  3KBP A;  4UWQ A;  2NPP C;  2IE4 C;  3AUZ A;  5F3W A;  1JK7 A;  3RL5 A;  3THO B;  4FBK A;  2NYM C;  4WWL A;  3N5U A;  3HVQ A;  3ZU0 A;  1OI8 A;  4H2I A;  3RL4 A;  1WAR A;  1OID A;  3AV0 A;  3T1I A;  2Z06 A;  1UF3 A;  3IVD A;  1SU1 A;  4ORB A;  1HO5 A;  5B8I A;  3JYF A;  4MP0 A;  1S3L A;  2QJC A;  2BQ8 X;  2WDC A;  3H63 A;  1T71 A;  2Z72 A;  3C5W C;  5JPE A;  1S3M A;  3K7V C;  2NXF A;  3K7W C;  1II7 A;  4ZX2 A;  2DFJ A;  1MF8 A;  5JPF A;  4O5G A;  4UT2 A;  3H60 A;  1AUI A;  4UT3 B;  3PSO A;  5C1V A;  2WDE A;  2USH A;  4Q7F A;  4ZVZ A;  1HP1 A;  3E7B A;  3IB7 A;  1IT6 A;  4H2G A;  1NNW A;  4V0X A;  2CV9 A;  3IVE A;  5J28 A;  4IYP C;  3H66 A;  2NYL C;  2A22 A;  4V0V A;  4H2B A;  3THN A;  3IB8 A;  4FBW A;  2R17 A;  3EGH A;  3GVE A;  3DSD A;  2O8G A;  1Z2W A;  5JJT A;  4M0V A;  3H61 A;  4V0W A;  1FJM A;  2QFP A;  1V73 A;  3EGG A;  1U32 A;  4B2O A;  5DNY A;  4H2F A;  4H1S A;  2BDX A;  4I5N C;  2Q8U A;  4O4K A;  4H1Y P;  1HPU A;  1T70 A;  2BCD A;  3V4Y A;  4MOY A;  2HY1 A;  2HYP A;  1KBP A;  1M63 A;  4XPN A;  3H64 A;  4O24 A;  2O8A A;  2IAE C;  3DSC A;  3DW8 C;  1S95 A;  2P6B A;  4HD0 A;  4F0Z A;  3H69 A;  1QFC A;  4JA7 A;  4LAC C;  1QHW A;  1G5B A;  4MOV A;  3LL8 A;  4YKE A;  1UTE A;  3E7A A;  3H68 A;  2YVT A;  4LTY A;  3RQZ A;  2WDD A;  2HYO A;  4O43 A;  5HPE A;  1Z2X A;  1S8E A;  5INB A;  5GTU A;  3QFK A;  1USH A;  1OIE A;  3FGA C;  3QFO A;  2ZBM A;  5IOH A;  4KKZ A;  2XMO A;  4DHL A; 
#chains in the Genus database with same CATH topology
 3C9F A;  3D03 A;  4ORA A;  4TUG A;  1TCO A;  4DSY A;  3TGH A;  4OR9 A;  4JA9 A;  1W24 A;  3CK2 A;  2JOG A;  3FLO A;  4TUI A;  2KKN A;  3ZTV A;  3H62 B;  1S3N A;  2AHD A;  4KBP A;  4J6O A;  3PSN A;  5EQV A;  4UT3 A;  4LU9 A;  4NZV A;  2QFR A;  2YEQ A;  1XZW A;  3P71 C;  4FCX A;  3ICF A;  4ORC A;  3RL3 A;  4DT2 A;  2GJU A;  2ZOA A;  2IE3 C;  4FBQ A;  3QG5 C;  3H67 A;  3QFM A;  4IL1 A;  2Z1A A;  4I5L C;  3QFN A;  1XM7 A;  2WDF A;  4G9J A;  1S70 A;  1WAO 1;  3KBP A;  4UWQ A;  2NPP C;  2IE4 C;  3AUZ A;  5F3W A;  1JK7 A;  3RL5 A;  3THO B;  4FBK A;  2NYM C;  4WWL A;  3N5U A;  3HVQ A;  3ZU0 A;  1OI8 A;  4H2I A;  3RL4 A;  1WAR A;  1OID A;  3AV0 A;  3T1I A;  2Z06 A;  1UF3 A;  3IVD A;  1SU1 A;  4ORB A;  1HO5 A;  5B8I A;  3JYF A;  4MP0 A;  3E0J A;  1S3L A;  2QJC A;  2BQ8 X;  2WDC A;  3H63 A;  1T71 A;  2Z72 A;  3C5W C;  5JPE A;  1S3M A;  3K7V C;  2NXF A;  3K7W C;  1II7 A;  4ZX2 A;  2DFJ A;  1MF8 A;  5JPF A;  4O5G A;  4UT2 A;  3H60 A;  1AUI A;  4UT3 B;  3PSO A;  5C1V A;  2WDE A;  2USH A;  4Q7F A;  4ZVZ A;  2DXN A;  1HP1 A;  3E7B A;  3IB7 A;  1IT6 A;  4H2G A;  1NNW A;  4V0X A;  2CV9 A;  3IVE A;  5J28 A;  4IYP C;  3H66 A;  2NYL C;  2A22 A;  4V0V A;  4H2B A;  3THN A;  3IB8 A;  4FBW A;  2R17 A;  3EGH A;  3GVE A;  3DSD A;  2O8G A;  1Z2W A;  5JJT A;  4M0V A;  3H61 A;  4V0W A;  1FJM A;  2QFP A;  1V73 A;  3EGG A;  1U32 A;  4B2O A;  5DNY A;  4H2F A;  2DXL A;  4H1S A;  2BDX A;  4I5N C;  2Q8U A;  4O4K A;  4H1Y P;  1HPU A;  1T70 A;  2BCD A;  3V4Y A;  4MOY A;  2HY1 A;  2HYP A;  1KBP A;  1M63 A;  4XPN A;  3H64 A;  4O24 A;  2O8A A;  2IAE C;  3DSC A;  3DW8 C;  1S95 A;  2P6B A;  4HD0 A;  4F0Z A;  3H69 A;  1QFC A;  4JA7 A;  4LAC C;  1QHW A;  1G5B A;  4MOV A;  3LL8 A;  4YKE A;  1UTE A;  3E7A A;  3H68 A;  2YVT A;  4LTY A;  2ZO9 B;  3RQZ A;  2WDD A;  2HYO A;  4O43 A;  5HPE A;  1Z2X A;  1S8E A;  5INB A;  5GTU A;  3QFK A;  1USH A;  1OIE A;  3FGA C;  3QFO A;  2ZBM A;  5IOH A;  4KKZ A;  2XMO A;  4DHL A; 
#chains in the Genus database with same CATH homology
 3C9F A;  3D03 A;  4ORA A;  4TUG A;  1TCO A;  4DSY A;  3TGH A;  4OR9 A;  4JA9 A;  1W24 A;  3CK2 A;  2JOG A;  3FLO A;  4TUI A;  2KKN A;  3ZTV A;  3H62 B;  1S3N A;  2AHD A;  4KBP A;  4J6O A;  3PSN A;  5EQV A;  4UT3 A;  4LU9 A;  4NZV A;  2QFR A;  2YEQ A;  1XZW A;  3P71 C;  4FCX A;  3ICF A;  4ORC A;  3RL3 A;  4DT2 A;  2GJU A;  2ZOA A;  2IE3 C;  4FBQ A;  3QG5 C;  3H67 A;  3QFM A;  4IL1 A;  2Z1A A;  4I5L C;  3QFN A;  1XM7 A;  2WDF A;  4G9J A;  1S70 A;  1WAO 1;  3KBP A;  4UWQ A;  2NPP C;  2IE4 C;  3AUZ A;  5F3W A;  1JK7 A;  3RL5 A;  3THO B;  4FBK A;  2NYM C;  4WWL A;  3N5U A;  3HVQ A;  3ZU0 A;  1OI8 A;  4H2I A;  3RL4 A;  1WAR A;  1OID A;  3AV0 A;  3T1I A;  2Z06 A;  1UF3 A;  3IVD A;  1SU1 A;  4ORB A;  1HO5 A;  5B8I A;  3JYF A;  4MP0 A;  3E0J A;  1S3L A;  2QJC A;  2BQ8 X;  2WDC A;  3H63 A;  1T71 A;  2Z72 A;  3C5W C;  5JPE A;  1S3M A;  3K7V C;  2NXF A;  3K7W C;  1II7 A;  4ZX2 A;  2DFJ A;  1MF8 A;  5JPF A;  4O5G A;  4UT2 A;  3H60 A;  1AUI A;  4UT3 B;  3PSO A;  5C1V A;  2WDE A;  2USH A;  4Q7F A;  4ZVZ A;  2DXN A;  1HP1 A;  3E7B A;  3IB7 A;  1IT6 A;  4H2G A;  1NNW A;  4V0X A;  2CV9 A;  3IVE A;  5J28 A;  4IYP C;  3H66 A;  2NYL C;  2A22 A;  4V0V A;  4H2B A;  3THN A;  3IB8 A;  4FBW A;  2R17 A;  3EGH A;  3GVE A;  3DSD A;  2O8G A;  1Z2W A;  5JJT A;  4M0V A;  3H61 A;  4V0W A;  1FJM A;  2QFP A;  1V73 A;  3EGG A;  1U32 A;  4B2O A;  5DNY A;  4H2F A;  2DXL A;  4H1S A;  2BDX A;  4I5N C;  2Q8U A;  4O4K A;  4H1Y P;  1HPU A;  1T70 A;  2BCD A;  3V4Y A;  4MOY A;  2HY1 A;  2HYP A;  1KBP A;  1M63 A;  4XPN A;  3H64 A;  4O24 A;  2O8A A;  2IAE C;  3DSC A;  3DW8 C;  1S95 A;  2P6B A;  4HD0 A;  4F0Z A;  3H69 A;  1QFC A;  4JA7 A;  4LAC C;  1QHW A;  1G5B A;  4MOV A;  3LL8 A;  4YKE A;  1UTE A;  3E7A A;  3H68 A;  2YVT A;  4LTY A;  2ZO9 B;  3RQZ A;  2WDD A;  2HYO A;  4O43 A;  5HPE A;  1Z2X A;  1S8E A;  5INB A;  5GTU A;  3QFK A;  1USH A;  1OIE A;  3FGA C;  3QFO A;  2ZBM A;  5IOH A;  4KKZ A;  2XMO A;  4DHL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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