4V0XA

The crystal structure of mouse pp1g in complex with truncated human ppp1r15b (631-684)
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
295
structure length
293
Chain Sequence
MLNIDSIIQRLLEVRGSGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase regulator
source organism Mus musculus
molecule keywords PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT
total genus 100
structure length 293
sequence length 295
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2014-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 4v0xA00
4O43A 3E7BA 4H1YP 4UT3B 2DFJA 1S95A 4J6OA 4V0WA 2WDCA 2WDDA 3HVQA 2IAEC 2NPPC 3H66A 4TUGA 3THOB 4H2IA 2NYMC 1QFCA 4KBPA 4O5GA 2HYPA 3E7AA 2AHDA 3K7WC 1KBPA 1QHWA 4ZX2A 4H2BA 1S8EA 2Z72A 1OIEA 1WAO1 4I5NC 4MOVA 2HYOA 4O24A 1XM7A 4IYPC 3EGGA 4FBQA 1IT6A 4B2OA 3GVEA 4H1SA 5IOHA 1UF3A 3EGHA 3H61A 4M0VA 2XMOA 3RL5A 1W24A 1SU1A 1WARA 3AV0A 3DSCA 3PSNA 4JA9A 3LL8A 3C9FA 2ZBMA 5EQVA 3IVDA 4UT2A 3T1IA 4ZVZA 4JA7A 2O8AA 3FGAC 4LTYA 1NNWA 3DW8C 1OI8A 1T71A 3QFNA 2QFPA 2Z1AA 2O8GA 5JJTA 5F3WA 1Z2WA 3PSOA 1XZWA 4I5LC 4H2FA 3V4YA 3THNA 3QFMA 1TCOA 2WDEA 4Q7FA 4FBWA 3H63A 4HD0A 2BQ8X 3RL3A 5B8IA 2Z06A 2JOGA 4YKEA 1AUIA 3H68A 2WDFA 5DNYA 2NXFA 3H69A 4LACC 2QFRA 1HO5A 1S3NA 3CK2A 4G9JA 1HPUA 5JPEA 4DHLA 1V73A 2USHA 3P71C 3RL4A 4DT2A 1OIDA 3H60A 5INBA 3TGHA 5HPEA 1U32A 4UWQA 2BDXA 1II7A 2IE4C 2KKNA 3H62B 4NZVA 1USHA 4OR9A 3H67A 3IB8A 1UTEA 4TUIA 4KKZA 2GJUA 4DSYA 4ORCA 1M63A 3QFOA 1S3LA 2A22A 2P6BA 3K7VC 2Q8UA 4UT3A 1Z2XA 1T70A 5JPFA 2R17A 4H2GA 4WWLA 3IVEA 2BCDA 4ORBA 2NYLC 4F0ZA 3QFKA 3IB7A 3AUZA 2CV9A 3C5WC 1JK7A 4FCXA 3ZU0A 3QG5C 2IE3C 5C1VA 1S70A 4IL1A 4MP0A 3KBPA 4ORAA 4O4KA 1FJMA 2YVTA 3DSDA 5GTUA 1G5BA 4V0VA 5J28A 4XPNA 3ZTVA 2QJCA 1HP1A 2HY1A 1MF8A 3H64A 1S3MA 3RQZA 4FBKA 3N5UA 3JYFA 4LU9A 4MOYA 3ICFA 4V0XA
chains in the Genus database with same CATH superfamily
4O43A 3E7BA 4H1YP 4UT3B 2DFJA 1S95A 4J6OA 4V0WA 2WDCA 2WDDA 3HVQA 2IAEC 2NPPC 2DXNA 3FLOA 3H66A 4TUGA 3THOB 4H2IA 2NYMC 1QFCA 4KBPA 4O5GA 2HYPA 3E7AA 2AHDA 3K7WC 1KBPA 1QHWA 4ZX2A 4H2BA 1S8EA 2Z72A 1OIEA 1WAO1 4I5NC 3D03A 4MOVA 2HYOA 4O24A 1XM7A 4IYPC 3EGGA 4FBQA 1IT6A 4B2OA 3GVEA 4H1SA 5IOHA 1UF3A 3EGHA 3H61A 4M0VA 2XMOA 3RL5A 1W24A 1SU1A 1WARA 3AV0A 3DSCA 3PSNA 4JA9A 3LL8A 3C9FA 2ZBMA 5EQVA 3IVDA 4UT2A 3T1IA 4ZVZA 4JA7A 2O8AA 3FGAC 4LTYA 1NNWA 3DW8C 1OI8A 1T71A 3QFNA 2QFPA 2Z1AA 2O8GA 2YEQA 5JJTA 5F3WA 1Z2WA 3PSOA 1XZWA 4I5LC 2DXLA 4H2FA 3THNA 3V4YA 3QFMA 1TCOA 2WDEA 4Q7FA 4FBWA 3H63A 4HD0A 2BQ8X 3RL3A 5B8IA 2JOGA 2Z06A 4YKEA 1AUIA 3H68A 2WDFA 5DNYA 2NXFA 3H69A 4LACC 2QFRA 1HO5A 1S3NA 3CK2A 4G9JA 1HPUA 5JPEA 4DHLA 1V73A 2USHA 3P71C 2ZOAA 3RL4A 4DT2A 1OIDA 3H60A 5INBA 3TGHA 5HPEA 1U32A 4UWQA 2BDXA 1II7A 2IE4C 2KKNA 3H62B 4NZVA 1USHA 2ZO9B 4OR9A 3H67A 3IB8A 1UTEA 4TUIA 4KKZA 2GJUA 4DSYA 4ORCA 1M63A 3QFOA 1S3LA 2A22A 2P6BA 3K7VC 2Q8UA 4UT3A 1Z2XA 1T70A 5JPFA 2R17A 4H2GA 4WWLA 3IVEA 2BCDA 4ORBA 2NYLC 4F0ZA 3QFKA 3IB7A 3AUZA 2CV9A 3C5WC 1JK7A 4FCXA 3ZU0A 3QG5C 2IE3C 5C1VA 1S70A 4IL1A 4MP0A 3KBPA 4ORAA 4O4KA 1FJMA 3E0JA 2YVTA 3DSDA 5GTUA 1G5BA 4V0VA 5J28A 4XPNA 3ZTVA 2QJCA 1HP1A 2HY1A 1MF8A 3H64A 1S3MA 3RQZA 4FBKA 3N5UA 3JYFA 4LU9A 4MOYA 3ICFA 4V0XA
chains in the Genus database with same CATH topology
4O43A 3E7BA 4H1YP 4UT3B 2DFJA 1S95A 4J6OA 4V0WA 2WDCA 2WDDA 3HVQA 2IAEC 2NPPC 2DXNA 3FLOA 3H66A 4TUGA 3THOB 4H2IA 2NYMC 1QFCA 4KBPA 4O5GA 2HYPA 3E7AA 2AHDA 3K7WC 1KBPA 1QHWA 4ZX2A 4H2BA 1S8EA 2Z72A 1OIEA 1WAO1 4I5NC 3D03A 4MOVA 2HYOA 4O24A 1XM7A 4IYPC 3EGGA 4FBQA 1IT6A 4B2OA 3GVEA 4H1SA 5IOHA 1UF3A 3EGHA 3H61A 4M0VA 2XMOA 3RL5A 1W24A 1SU1A 1WARA 3AV0A 3DSCA 3PSNA 4JA9A 3LL8A 3C9FA 2ZBMA 5EQVA 3IVDA 4UT2A 3T1IA 4ZVZA 4JA7A 2O8AA 3FGAC 4LTYA 1NNWA 3DW8C 1OI8A 1T71A 3QFNA 2QFPA 2Z1AA 2O8GA 2YEQA 5JJTA 5F3WA 1Z2WA 3PSOA 1XZWA 4I5LC 2DXLA 4H2FA 3THNA 3V4YA 3QFMA 1TCOA 2WDEA 4Q7FA 4FBWA 3H63A 4HD0A 2BQ8X 3RL3A 5B8IA 2JOGA 2Z06A 4YKEA 1AUIA 3H68A 2WDFA 5DNYA 2NXFA 3H69A 4LACC 2QFRA 1HO5A 1S3NA 3CK2A 4G9JA 1HPUA 5JPEA 4DHLA 1V73A 2USHA 3P71C 2ZOAA 3RL4A 4DT2A 1OIDA 3H60A 5INBA 3TGHA 5HPEA 1U32A 4UWQA 2BDXA 1II7A 2IE4C 2KKNA 3H62B 4NZVA 1USHA 2ZO9B 4OR9A 3H67A 3IB8A 1UTEA 4TUIA 4KKZA 2GJUA 4DSYA 4ORCA 1M63A 3QFOA 1S3LA 2A22A 2P6BA 3K7VC 2Q8UA 4UT3A 1Z2XA 1T70A 5JPFA 2R17A 4H2GA 4WWLA 3IVEA 2BCDA 4ORBA 2NYLC 4F0ZA 3QFKA 3IB7A 3AUZA 2CV9A 3C5WC 1JK7A 4FCXA 3ZU0A 3QG5C 2IE3C 5C1VA 1S70A 4IL1A 4MP0A 3KBPA 4ORAA 4O4KA 1FJMA 3E0JA 2YVTA 3DSDA 5GTUA 1G5BA 4V0VA 5J28A 4XPNA 3ZTVA 2QJCA 1HP1A 2HY1A 1MF8A 3H64A 1S3MA 3RQZA 4FBKA 3N5UA 3JYFA 4LU9A 4MOYA 3ICFA 4V0XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O43 A;  3E7B A;  4H1Y P;  4UT3 B;  2DFJ A;  1S95 A;  4J6O A;  4V0W A;  2WDC A;  2WDD A;  3HVQ A;  2IAE C;  2NPP C;  3H66 A;  4TUG A;  3THO B;  4H2I A;  2NYM C;  1QFC A;  4KBP A;  4O5G A;  2HYP A;  3E7A A;  2AHD A;  3K7W C;  1KBP A;  1QHW A;  4ZX2 A;  4H2B A;  1S8E A;  2Z72 A;  1OIE A;  1WAO 1;  4I5N C;  4MOV A;  2HYO A;  4O24 A;  1XM7 A;  4IYP C;  3EGG A;  4FBQ A;  1IT6 A;  4B2O A;  3GVE A;  4H1S A;  5IOH A;  1UF3 A;  3EGH A;  3H61 A;  4M0V A;  2XMO A;  3RL5 A;  1W24 A;  1SU1 A;  1WAR A;  3AV0 A;  3DSC A;  3PSN A;  4JA9 A;  3LL8 A;  3C9F A;  2ZBM A;  5EQV A;  3IVD A;  4UT2 A;  3T1I A;  4ZVZ A;  4JA7 A;  2O8A A;  3FGA C;  4LTY A;  1NNW A;  3DW8 C;  1OI8 A;  1T71 A;  3QFN A;  2QFP A;  2Z1A A;  2O8G A;  5JJT A;  5F3W A;  1Z2W A;  3PSO A;  1XZW A;  4I5L C;  4H2F A;  3V4Y A;  3THN A;  3QFM A;  1TCO A;  2WDE A;  4Q7F A;  4FBW A;  3H63 A;  4HD0 A;  2BQ8 X;  3RL3 A;  5B8I A;  2Z06 A;  2JOG A;  4YKE A;  1AUI A;  3H68 A;  2WDF A;  5DNY A;  2NXF A;  3H69 A;  4LAC C;  2QFR A;  1HO5 A;  1S3N A;  3CK2 A;  4G9J A;  1HPU A;  5JPE A;  4DHL A;  1V73 A;  2USH A;  3P71 C;  3RL4 A;  4DT2 A;  1OID A;  3H60 A;  5INB A;  3TGH A;  5HPE A;  1U32 A;  4UWQ A;  2BDX A;  1II7 A;  2IE4 C;  2KKN A;  3H62 B;  4NZV A;  1USH A;  4OR9 A;  3H67 A;  3IB8 A;  1UTE A;  4TUI A;  4KKZ A;  2GJU A;  4DSY A;  4ORC A;  1M63 A;  3QFO A;  1S3L A;  2A22 A;  2P6B A;  3K7V C;  2Q8U A;  4UT3 A;  1Z2X A;  1T70 A;  5JPF A;  2R17 A;  4H2G A;  4WWL A;  3IVE A;  2BCD A;  4ORB A;  2NYL C;  4F0Z A;  3QFK A;  3IB7 A;  3AUZ A;  2CV9 A;  3C5W C;  1JK7 A;  4FCX A;  3ZU0 A;  3QG5 C;  2IE3 C;  5C1V A;  1S70 A;  4IL1 A;  4MP0 A;  3KBP A;  4ORA A;  4O4K A;  1FJM A;  2YVT A;  3DSD A;  5GTU A;  1G5B A;  4V0V A;  5J28 A;  4XPN A;  3ZTV A;  2QJC A;  1HP1 A;  2HY1 A;  1MF8 A;  3H64 A;  1S3M A;  3RQZ A;  4FBK A;  3N5U A;  3JYF A;  4LU9 A;  4MOY A;  3ICF A;  4V0X A; 
#chains in the Genus database with same CATH topology
 4O43 A;  3E7B A;  4H1Y P;  4UT3 B;  2DFJ A;  1S95 A;  4J6O A;  4V0W A;  2WDC A;  2WDD A;  3HVQ A;  2IAE C;  2NPP C;  2DXN A;  3FLO A;  3H66 A;  4TUG A;  3THO B;  4H2I A;  2NYM C;  1QFC A;  4KBP A;  4O5G A;  2HYP A;  3E7A A;  2AHD A;  3K7W C;  1KBP A;  1QHW A;  4ZX2 A;  4H2B A;  1S8E A;  2Z72 A;  1OIE A;  1WAO 1;  4I5N C;  3D03 A;  4MOV A;  2HYO A;  4O24 A;  1XM7 A;  4IYP C;  3EGG A;  4FBQ A;  1IT6 A;  4B2O A;  3GVE A;  4H1S A;  5IOH A;  1UF3 A;  3EGH A;  3H61 A;  4M0V A;  2XMO A;  3RL5 A;  1W24 A;  1SU1 A;  1WAR A;  3AV0 A;  3DSC A;  3PSN A;  4JA9 A;  3LL8 A;  3C9F A;  2ZBM A;  5EQV A;  3IVD A;  4UT2 A;  3T1I A;  4ZVZ A;  4JA7 A;  2O8A A;  3FGA C;  4LTY A;  1NNW A;  3DW8 C;  1OI8 A;  1T71 A;  3QFN A;  2QFP A;  2Z1A A;  2O8G A;  2YEQ A;  5JJT A;  5F3W A;  1Z2W A;  3PSO A;  1XZW A;  4I5L C;  2DXL A;  4H2F A;  3THN A;  3V4Y A;  3QFM A;  1TCO A;  2WDE A;  4Q7F A;  4FBW A;  3H63 A;  4HD0 A;  2BQ8 X;  3RL3 A;  5B8I A;  2JOG A;  2Z06 A;  4YKE A;  1AUI A;  3H68 A;  2WDF A;  5DNY A;  2NXF A;  3H69 A;  4LAC C;  2QFR A;  1HO5 A;  1S3N A;  3CK2 A;  4G9J A;  1HPU A;  5JPE A;  4DHL A;  1V73 A;  2USH A;  3P71 C;  2ZOA A;  3RL4 A;  4DT2 A;  1OID A;  3H60 A;  5INB A;  3TGH A;  5HPE A;  1U32 A;  4UWQ A;  2BDX A;  1II7 A;  2IE4 C;  2KKN A;  3H62 B;  4NZV A;  1USH A;  2ZO9 B;  4OR9 A;  3H67 A;  3IB8 A;  1UTE A;  4TUI A;  4KKZ A;  2GJU A;  4DSY A;  4ORC A;  1M63 A;  3QFO A;  1S3L A;  2A22 A;  2P6B A;  3K7V C;  2Q8U A;  4UT3 A;  1Z2X A;  1T70 A;  5JPF A;  2R17 A;  4H2G A;  4WWL A;  3IVE A;  2BCD A;  4ORB A;  2NYL C;  4F0Z A;  3QFK A;  3IB7 A;  3AUZ A;  2CV9 A;  3C5W C;  1JK7 A;  4FCX A;  3ZU0 A;  3QG5 C;  2IE3 C;  5C1V A;  1S70 A;  4IL1 A;  4MP0 A;  3KBP A;  4ORA A;  4O4K A;  1FJM A;  3E0J A;  2YVT A;  3DSD A;  5GTU A;  1G5B A;  4V0V A;  5J28 A;  4XPN A;  3ZTV A;  2QJC A;  1HP1 A;  2HY1 A;  1MF8 A;  3H64 A;  1S3M A;  3RQZ A;  4FBK A;  3N5U A;  3JYF A;  4LU9 A;  4MOY A;  3ICF A;  4V0X A; 
#chains in the Genus database with same CATH homology
 4O43 A;  3E7B A;  4H1Y P;  4UT3 B;  2DFJ A;  1S95 A;  4J6O A;  4V0W A;  2WDC A;  2WDD A;  3HVQ A;  2IAE C;  2NPP C;  2DXN A;  3FLO A;  3H66 A;  4TUG A;  3THO B;  4H2I A;  2NYM C;  1QFC A;  4KBP A;  4O5G A;  2HYP A;  3E7A A;  2AHD A;  3K7W C;  1KBP A;  1QHW A;  4ZX2 A;  4H2B A;  1S8E A;  2Z72 A;  1OIE A;  1WAO 1;  4I5N C;  3D03 A;  4MOV A;  2HYO A;  4O24 A;  1XM7 A;  4IYP C;  3EGG A;  4FBQ A;  1IT6 A;  4B2O A;  3GVE A;  4H1S A;  5IOH A;  1UF3 A;  3EGH A;  3H61 A;  4M0V A;  2XMO A;  3RL5 A;  1W24 A;  1SU1 A;  1WAR A;  3AV0 A;  3DSC A;  3PSN A;  4JA9 A;  3LL8 A;  3C9F A;  2ZBM A;  5EQV A;  3IVD A;  4UT2 A;  3T1I A;  4ZVZ A;  4JA7 A;  2O8A A;  3FGA C;  4LTY A;  1NNW A;  3DW8 C;  1OI8 A;  1T71 A;  3QFN A;  2QFP A;  2Z1A A;  2O8G A;  2YEQ A;  5JJT A;  5F3W A;  1Z2W A;  3PSO A;  1XZW A;  4I5L C;  2DXL A;  4H2F A;  3THN A;  3V4Y A;  3QFM A;  1TCO A;  2WDE A;  4Q7F A;  4FBW A;  3H63 A;  4HD0 A;  2BQ8 X;  3RL3 A;  5B8I A;  2JOG A;  2Z06 A;  4YKE A;  1AUI A;  3H68 A;  2WDF A;  5DNY A;  2NXF A;  3H69 A;  4LAC C;  2QFR A;  1HO5 A;  1S3N A;  3CK2 A;  4G9J A;  1HPU A;  5JPE A;  4DHL A;  1V73 A;  2USH A;  3P71 C;  2ZOA A;  3RL4 A;  4DT2 A;  1OID A;  3H60 A;  5INB A;  3TGH A;  5HPE A;  1U32 A;  4UWQ A;  2BDX A;  1II7 A;  2IE4 C;  2KKN A;  3H62 B;  4NZV A;  1USH A;  2ZO9 B;  4OR9 A;  3H67 A;  3IB8 A;  1UTE A;  4TUI A;  4KKZ A;  2GJU A;  4DSY A;  4ORC A;  1M63 A;  3QFO A;  1S3L A;  2A22 A;  2P6B A;  3K7V C;  2Q8U A;  4UT3 A;  1Z2X A;  1T70 A;  5JPF A;  2R17 A;  4H2G A;  4WWL A;  3IVE A;  2BCD A;  4ORB A;  2NYL C;  4F0Z A;  3QFK A;  3IB7 A;  3AUZ A;  2CV9 A;  3C5W C;  1JK7 A;  4FCX A;  3ZU0 A;  3QG5 C;  2IE3 C;  5C1V A;  1S70 A;  4IL1 A;  4MP0 A;  3KBP A;  4ORA A;  4O4K A;  1FJM A;  3E0J A;  2YVT A;  3DSD A;  5GTU A;  1G5B A;  4V0V A;  5J28 A;  4XPN A;  3ZTV A;  2QJC A;  1HP1 A;  2HY1 A;  1MF8 A;  3H64 A;  1S3M A;  3RQZ A;  4FBK A;  3N5U A;  3JYF A;  4LU9 A;  4MOY A;  3ICF A;  4V0X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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