4X6AL

Crystal structure of yeast rna polymerase ii encountering oxidative cyclopurine dna lesions
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.
pubmed doi rcsb
molecule tags Transcription/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2014-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4x6aL00
1I50L 2JA7L 3M4OL 4A93L 4QIWP 5C4JL 3H0GL 3M3YL 4Y52L 4A3BL 1TWHL 4A3CL 5IP7L 3K7AL 4BBSL 5IYBL 3GTKL 2R7ZL 2WB1P 1Y1WL 3GTLL 3HOWL 3I4NL 3S16L 3RZDL 5M3FL 3GTOL 5M3ML 2R92L 4BXXL 4AYBP 3FKIL 3RZOL 2R93L 3H3VM 4A3KL 4A3FL 5C3EL 2NVTL 1TWAL 3GTPL 4C2M1 3GTQL 3HOYL 2NVYL 5C44L 3S1NL 4A3LL 1TWFL 4A3ML 4BY7L 2Y0SP 5IYDL 2YU9L 4C3JL 2NVQL 2E2JL 5M5XL 3CQZL 1I3QL 5FLML 3HOXL 3GTJL 2NVXL 3S1RL 3S14L 5FJ8L 4X6AL 3GTML 1I6HL 1TWGL 2PMZP 2B63L 2E2IL 5M5WL 4Y7NL 2E2HL 3S1QL 3GTGL 5IYCL 1SFOL 4A3DL 3S1ML 4A3IL 5C4XL 4A3EL 4BY1L 3HKZP 5M5YL 2JA8L 5IP9L 3S17L 3HOVL 3S2HL 3PO2L 4A3JL 3HOZL 4C3IL 4C3HL 1WCML 3PO3L 3S15L 4BBRL 2JA5L 3I4ML 1Y1VL 2JA6L 1TWCL 2WAQP 4A3GL 1R9TL 2VUML 3S2DL 1K83L 3HOUL
chains in the Genus database with same CATH superfamily
3PL5A 5GAHc 1S2ZA 3M3YL 2V0EA 1R0FA 1P7PA 2HVYC 5IYBL 4BBSL 3ZG6A 2CKAA 3RZDL 4V196 3GTOL 5M3ML 4AYBP 1T9QA 3NFPI 3PWFA 5RXNA 1R0HA 4A3KL 2L0ZA 5GAGc 1NNQA 5MF6A 2NVTL 1H7VA 2BE5D 5MFPA 2NVYL 1QQTA 4A3LL 2QL0A 5AI2A 4A3ML 2B5ID 2ERSA 4C3JL 2NVQL 2E2JL 5M5XL 1RDVA 1FHMA 1YUXA 2Z3RB 1ODHA 3S14L 3J7Z1 3K35A 2PMZP 4K9FA 2B63L 5M5WL 4RXNA 2Z3QB 1E8JA 4B8CD 3LWVB 1BFYA 2LCQA 1PFVA 3MPSA 1DX8A 2HR5A 4A3JL 2GMGA 2KN9A 4TVMA 1WCML 4AR5A 1LKMA 2JA5L 2NYDA 3KYXA 1IRNA 2PVXA 2V0FA 3JR7A 1R9TL 3PKJA 4POGA 5EIOC 3MSUA 2XJQA 3M4OL 4YWLA 4A3BL 3HAXC 4A3CL 5IP7L 7RXNA 2A68D 3FDJA 3LWPB 2WB1P 1YK4A 4U671 3GTLL 3HOWL 2V3BB 4E6YA 2RFKB 2M6OA 4AHWA 2K2DA 3FKIL 1B13A 3B08B 1SMUA 4AHYA 1JYBA 2C6BA 3H3VM 4A3FL 3A44A 3MQKB 3J7Y1 1PFWA 4JAFA 1S30A 3B0AB 3GTQL 1RDGA 2AUSB 1R0GA 3PIO1 2H12A 1OWBA 1VZIA 1YK5A 2YU9L 3CQZL 5FLML 5MLC3 4UY81 4WFN1 2RDVA 1LKPA 3KYVA 4AHZA 2JI2A 1I6HL 1TWGL 2MS3A 2JI3A 3LPEB 2VL6A 1CADA 4JAEA 3HJYB 1SFOL 3S1ML 1RWDA 3HKZP 3S17L 3S2HL 3PO2L 4XXBB 2XJSA 1BE7A 1VZHA 3H9BA 1C09A 3LWQB 1NXEA 4AHXA 3I4ML 1Y1VL 4G6BA 2PYAA 1BQ9A 5JVG1 2AYJA 1I50L 5C4JL 3H0GL 2C6AA 4ZN3B 3KYYA 2XJUA 4Y52L 1B71A 5K2ME 3SS2A 3K7AL 1R0JA 1Y1WL 1WJVA 2A6ED 2PSMC 3HJWB 3S16L 5M3FL 4YWMA 1PZXA 2PPTA 3H97A 5IY0A 2R92L 2A69D 2R93L 1IW7D 1QCVA 1PFUA 4AR6A 5C3EL 5MFZA 3GTPL 1QYBA 5C44L 3LWRB 3S1NL 5GAEc 2KKDA 1RYTA 4BY7L 2Y0SP 4ME3A 1I3QL 1RB9A 3GTJL 2NVXL 3PIP1 5FJ8L 4AI1A 4X6AL 3QVDA 5DM61 3RZTA 2AQCA 2E2IL 2CKCA 4JAGA 5DM71 4Y7NL 1PFYA 1IU5A 4AR3A 5JVH1 4AR4A 3S1QL 5IYCL 4A3IL 5C4XL 2M4YA 1F4LA 4BY1L 2JA8L 4JADA 2XJTA 4C3IL 4C3HL 3PO3L 4BBRL 4XGHA 1YV1A 2WAQP 4A3GL 1LKOA 2VUML 4ZN1B 2ERJA 1S24A 5GADc 2JA7L 4A93L 3RZ6A 4QIWP 4LHNA 2J9UB 5EINC 1TWHL 1FHHA 1BRFA 1Z92B 1CAAA 3GTKL 2R7ZL 1DVBA 4AI2A 4LHLA 3KYUA 3I4NL 2DSXA 2ZIXA 4GS7D 4BXXL 3RZOL 3LNLA 2APOB 6RXNA 1TWAL 5AI3A 2XJPA 1VCXA 4C2M1 8RXNA 3HOYL 1TWFL 3PKIA 3IU3I 1LTLA 5IYDL 3WWNB 3H9CA 1OWCA 3P2AA 3VPBE 1NXGA 3HOXL 3PZAA 2JI1A 5AN9H 3S1RL 3KYWA 1T9PA 1IROA 5MGNA 3GTML 3LWOB 1ZRPA 2EY4E 4POFA 1R0IA 1IU6A 1T9OA 1SMWA 2E2HL 1BQ8A 3QQCE 3WWLA 2XJRA 3GTGL 4A3DL 4TPUA 4A3EL 5H1Sc 1VZGA 4AI0A 5M5YL 1B2OA 5IP9L 3HOVL 1SMMA 3HOZL 3S15L 3P8BA 4AI3A 1RYQA 2JA6L 3H99A 2M6PA 2O5JD 1TWCL 2PVEA 1B2JA 2A6HD 2CR8A 1YUZA 3S2DL 2XJVA 1K83L 3RYGA 3HOUL 2M4VA
chains in the Genus database with same CATH topology
1I50L 2JA7L 3M4OL 4A93L 4QIWP 5C4JL 3H0GL 3M3YL 4Y52L 4A3BL 1TWHL 4A3CL 5IP7L 3K7AL 4BBSL 5IYBL 3GTKL 2R7ZL 2WB1P 1Y1WL 3GTLL 3HOWL 3I4NL 3S16L 3RZDL 5M3FL 3GTOL 5M3ML 2R92L 4BXXL 4AYBP 3FKIL 3RZOL 2R93L 3H3VM 4A3KL 4A3FL 5C3EL 2NVTL 1TWAL 3GTPL 4C2M1 3GTQL 3HOYL 2NVYL 5C44L 3S1NL 4A3LL 1TWFL 4A3ML 4BY7L 2Y0SP 5IYDL 2YU9L 4C3JL 2NVQL 2E2JL 5M5XL 3CQZL 1I3QL 5FLML 3HOXL 3GTJL 2NVXL 3S1RL 3S14L 5FJ8L 4X6AL 3GTML 1I6HL 1TWGL 2PMZP 2B63L 2E2IL 5M5WL 4Y7NL 2E2HL 3S1QL 3GTGL 5IYCL 1SFOL 4A3DL 3S1ML 4A3IL 5C4XL 4A3EL 4BY1L 3HKZP 5M5YL 2JA8L 5IP9L 3S17L 3HOVL 3S2HL 3PO2L 4A3JL 3HOZL 4C3IL 4C3HL 1WCML 3PO3L 3S15L 4BBRL 2JA5L 3I4ML 1Y1VL 2JA6L 1TWCL 2WAQP 4A3GL 1R9TL 2VUML 3S2DL 1K83L 3HOUL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I50 L;  2JA7 L;  3M4O L;  4A93 L;  4QIW P;  5C4J L;  3H0G L;  3M3Y L;  4Y52 L;  4A3B L;  1TWH L;  4A3C L;  5IP7 L;  3K7A L;  4BBS L;  5IYB L;  3GTK L;  2R7Z L;  2WB1 P;  1Y1W L;  3GTL L;  3HOW L;  3I4N L;  3S16 L;  3RZD L;  5M3F L;  3GTO L;  5M3M L;  2R92 L;  4BXX L;  4AYB P;  3FKI L;  3RZO L;  2R93 L;  3H3V M;  4A3K L;  4A3F L;  5C3E L;  2NVT L;  1TWA L;  3GTP L;  4C2M 1;  3GTQ L;  3HOY L;  2NVY L;  5C44 L;  3S1N L;  4A3L L;  1TWF L;  4A3M L;  4BY7 L;  2Y0S P;  5IYD L;  2YU9 L;  4C3J L;  2NVQ L;  2E2J L;  5M5X L;  3CQZ L;  1I3Q L;  5FLM L;  3HOX L;  3GTJ L;  2NVX L;  3S1R L;  3S14 L;  5FJ8 L;  4X6A L;  3GTM L;  1I6H L;  1TWG L;  2PMZ P;  2B63 L;  2E2I L;  5M5W L;  4Y7N L;  2E2H L;  3S1Q L;  3GTG L;  5IYC L;  1SFO L;  4A3D L;  3S1M L;  4A3I L;  5C4X L;  4A3E L;  4BY1 L;  3HKZ P;  5M5Y L;  2JA8 L;  5IP9 L;  3S17 L;  3HOV L;  3S2H L;  3PO2 L;  4A3J L;  3HOZ L;  4C3I L;  4C3H L;  1WCM L;  3PO3 L;  3S15 L;  4BBR L;  2JA5 L;  3I4M L;  1Y1V L;  2JA6 L;  1TWC L;  2WAQ P;  4A3G L;  1R9T L;  2VUM L;  3S2D L;  1K83 L;  3HOU L; 
#chains in the Genus database with same CATH topology
 3PL5 A;  5GAH c;  1S2Z A;  3M3Y L;  2V0E A;  1R0F A;  1P7P A;  2HVY C;  5IYB L;  4BBS L;  3ZG6 A;  2CKA A;  3RZD L;  4V19 6;  3GTO L;  5M3M L;  4AYB P;  1T9Q A;  3NFP I;  3PWF A;  5RXN A;  1R0H A;  4A3K L;  2L0Z A;  5GAG c;  1NNQ A;  5MF6 A;  2NVT L;  1H7V A;  2BE5 D;  5MFP A;  2NVY L;  1QQT A;  4A3L L;  2QL0 A;  5AI2 A;  4A3M L;  2B5I D;  2ERS A;  4C3J L;  2NVQ L;  2E2J L;  5M5X L;  1RDV A;  1FHM A;  1YUX A;  2Z3R B;  1ODH A;  3S14 L;  3J7Z 1;  3K35 A;  2PMZ P;  4K9F A;  2B63 L;  5M5W L;  4RXN A;  2Z3Q B;  1E8J A;  4B8C D;  3LWV B;  1BFY A;  2LCQ A;  1PFV A;  3MPS A;  1DX8 A;  2HR5 A;  4A3J L;  2GMG A;  2KN9 A;  4TVM A;  1WCM L;  4AR5 A;  1LKM A;  2JA5 L;  2NYD A;  3KYX A;  1IRN A;  2PVX A;  2V0F A;  3JR7 A;  1R9T L;  3PKJ A;  4POG A;  5EIO C;  3MSU A;  2XJQ A;  3M4O L;  4YWL A;  4A3B L;  3HAX C;  4A3C L;  5IP7 L;  7RXN A;  2A68 D;  3FDJ A;  3LWP B;  2WB1 P;  1YK4 A;  4U67 1;  3GTL L;  3HOW L;  2V3B B;  4E6Y A;  2RFK B;  2M6O A;  4AHW A;  2K2D A;  3FKI L;  1B13 A;  3B08 B;  1SMU A;  4AHY A;  1JYB A;  2C6B A;  3H3V M;  4A3F L;  3A44 A;  3MQK B;  3J7Y 1;  1PFW A;  4JAF A;  1S30 A;  3B0A B;  3GTQ L;  1RDG A;  2AUS B;  1R0G A;  3PIO 1;  2H12 A;  1OWB A;  1VZI A;  1YK5 A;  2YU9 L;  3CQZ L;  5FLM L;  5MLC 3;  4UY8 1;  4WFN 1;  2RDV A;  1LKP A;  3KYV A;  4AHZ A;  2JI2 A;  1I6H L;  1TWG L;  2MS3 A;  2JI3 A;  3LPE B;  2VL6 A;  1CAD A;  4JAE A;  3HJY B;  1SFO L;  3S1M L;  1RWD A;  3HKZ P;  3S17 L;  3S2H L;  3PO2 L;  4XXB B;  2XJS A;  1BE7 A;  1VZH A;  3H9B A;  1C09 A;  3LWQ B;  1NXE A;  4AHX A;  3I4M L;  1Y1V L;  4G6B A;  2PYA A;  1BQ9 A;  5JVG 1;  2AYJ A;  1I50 L;  5C4J L;  3H0G L;  2C6A A;  4ZN3 B;  3KYY A;  2XJU A;  4Y52 L;  1B71 A;  5K2M E;  3SS2 A;  3K7A L;  1R0J A;  1Y1W L;  1WJV A;  2A6E D;  2PSM C;  3HJW B;  3S16 L;  5M3F L;  4YWM A;  1PZX A;  2PPT A;  3H97 A;  5IY0 A;  2R92 L;  2A69 D;  2R93 L;  1IW7 D;  1QCV A;  1PFU A;  4AR6 A;  5C3E L;  5MFZ A;  3GTP L;  1QYB A;  5C44 L;  3LWR B;  3S1N L;  5GAE c;  2KKD A;  1RYT A;  4BY7 L;  2Y0S P;  4ME3 A;  1I3Q L;  1RB9 A;  3GTJ L;  2NVX L;  3PIP 1;  5FJ8 L;  4AI1 A;  4X6A L;  3QVD A;  5DM6 1;  3RZT A;  2AQC A;  2E2I L;  2CKC A;  4JAG A;  5DM7 1;  4Y7N L;  1PFY A;  1IU5 A;  4AR3 A;  5JVH 1;  4AR4 A;  3S1Q L;  5IYC L;  4A3I L;  5C4X L;  2M4Y A;  1F4L A;  4BY1 L;  2JA8 L;  4JAD A;  2XJT A;  4C3I L;  4C3H L;  3PO3 L;  4BBR L;  4XGH A;  1YV1 A;  2WAQ P;  4A3G L;  1LKO A;  2VUM L;  4ZN1 B;  2ERJ A;  1S24 A;  5GAD c;  2JA7 L;  4A93 L;  3RZ6 A;  4QIW P;  4LHN A;  2J9U B;  5EIN C;  1TWH L;  1FHH A;  1BRF A;  1Z92 B;  1CAA A;  3GTK L;  2R7Z L;  1DVB A;  4AI2 A;  4LHL A;  3KYU A;  3I4N L;  2DSX A;  2ZIX A;  4GS7 D;  4BXX L;  3RZO L;  3LNL A;  2APO B;  6RXN A;  1TWA L;  5AI3 A;  2XJP A;  1VCX A;  4C2M 1;  8RXN A;  3HOY L;  1TWF L;  3PKI A;  3IU3 I;  1LTL A;  5IYD L;  3WWN B;  3H9C A;  1OWC A;  3P2A A;  3VPB E;  1NXG A;  3HOX L;  3PZA A;  2JI1 A;  5AN9 H;  3S1R L;  3KYW A;  1T9P A;  1IRO A;  5MGN A;  3GTM L;  3LWO B;  1ZRP A;  2EY4 E;  4POF A;  1R0I A;  1IU6 A;  1T9O A;  1SMW A;  2E2H L;  1BQ8 A;  3QQC E;  3WWL A;  2XJR A;  3GTG L;  4A3D L;  4TPU A;  4A3E L;  5H1S c;  1VZG A;  4AI0 A;  5M5Y L;  1B2O A;  5IP9 L;  3HOV L;  1SMM A;  3HOZ L;  3S15 L;  3P8B A;  4AI3 A;  1RYQ A;  2JA6 L;  3H99 A;  2M6P A;  2O5J D;  1TWC L;  2PVE A;  1B2J A;  2A6H D;  2CR8 A;  1YUZ A;  3S2D L;  2XJV A;  1K83 L;  3RYG A;  3HOU L;  2M4V A; 
#chains in the Genus database with same CATH homology
 1I50 L;  2JA7 L;  3M4O L;  4A93 L;  4QIW P;  5C4J L;  3H0G L;  3M3Y L;  4Y52 L;  4A3B L;  1TWH L;  4A3C L;  5IP7 L;  3K7A L;  4BBS L;  5IYB L;  3GTK L;  2R7Z L;  2WB1 P;  1Y1W L;  3GTL L;  3HOW L;  3I4N L;  3S16 L;  3RZD L;  5M3F L;  3GTO L;  5M3M L;  2R92 L;  4BXX L;  4AYB P;  3FKI L;  3RZO L;  2R93 L;  3H3V M;  4A3K L;  4A3F L;  5C3E L;  2NVT L;  1TWA L;  3GTP L;  4C2M 1;  3GTQ L;  3HOY L;  2NVY L;  5C44 L;  3S1N L;  4A3L L;  1TWF L;  4A3M L;  4BY7 L;  2Y0S P;  5IYD L;  2YU9 L;  4C3J L;  2NVQ L;  2E2J L;  5M5X L;  3CQZ L;  1I3Q L;  5FLM L;  3HOX L;  3GTJ L;  2NVX L;  3S1R L;  3S14 L;  5FJ8 L;  4X6A L;  3GTM L;  1I6H L;  1TWG L;  2PMZ P;  2B63 L;  2E2I L;  5M5W L;  4Y7N L;  2E2H L;  3S1Q L;  3GTG L;  5IYC L;  1SFO L;  4A3D L;  3S1M L;  4A3I L;  5C4X L;  4A3E L;  4BY1 L;  3HKZ P;  5M5Y L;  2JA8 L;  5IP9 L;  3S17 L;  3HOV L;  3S2H L;  3PO2 L;  4A3J L;  3HOZ L;  4C3I L;  4C3H L;  1WCM L;  3PO3 L;  3S15 L;  4BBR L;  2JA5 L;  3I4M L;  1Y1V L;  2JA6 L;  1TWC L;  2WAQ P;  4A3G L;  1R9T L;  2VUM L;  3S2D L;  1K83 L;  3HOU L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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