4X6AL

Crystal structure of yeast rna polymerase ii encountering oxidative cyclopurine dna lesions
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription/dna
publication title Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2014-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4x6aL00
5IYBL 5FLML 4C3HL 4A3FL 3GTML 4A93L 3S2DL 3GTLL 3PO3L 4C3JL 3S1NL 4C2M1 3S1RL 4BY7L 4Y52L 3S1ML 2B63L 2WAQP 1Y1WL 1R9TL 4A3LL 3M3YL 2VUML 2R93L 3RZDL 4A3CL 3HOVL 2PMZP 2JA7L 3HOZL 4Y7NL 4A3EL 4A3BL 2Y0SP 3S16L 4QIWP 2R7ZL 1TWAL 3GTKL 3GTOL 3S1QL 3K7AL 1TWCL 1I3QL 4BBRL 2WB1P 4A3DL 3GTPL 3H0GL 5IP9L 3GTGL 3CQZL 3PO2L 1SFOL 5M5WL 3HOWL 2NVYL 2NVXL 1TWFL 4AYBP 1TWHL 1I50L 3I4NL 3HKZP 4A3JL 5IYCL 3S2HL 1Y1VL 2NVQL 2JA6L 5C44L 3FKIL 1TWGL 3GTQL 3H3VM 2E2JL 5FJ8L 2E2HL 3S17L 4A3ML 4BBSL 4BXXL 5M3ML 5M3FL 5C4JL 3HOYL 5IP7L 3I4ML 4X6AL 3GTJL 3RZOL 3S15L 2JA8L 3S14L 2JA5L 2E2IL 4A3KL 3HOUL 3M4OL 4A3GL 5C3EL 4C3IL 4BY1L 1WCML 4A3IL 5C4XL 5M5YL 5IYDL 1K83L 1I6HL 3HOXL 5M5XL 2NVTL 2YU9L 2R92L
chains in the Genus database with same CATH superfamily
5FLML 1BE7A 1LKMA 1RDGA 3PO3L 1T9OA 3PL5A 3IU3I 3HAXC 3HJYB 1IU5A 4Y52L 1RYQA 1R0GA 4AR3A 2M4YA 3JR7A 5JVH1 3HOZL 4A3BL 2Y0SP 2PVEA 1RDVA 1TWCL 2JI3A 4A3DL 2C6AA 1QYBA 1NXGA 3PO2L 1SFOL 2NVYL 2J9UB 4B8CD 4XXBB 5RXNA 5AN9H 2LCQA 3K35A 4ME3A 3H99A 2H12A 1YK4A 3PWFA 2A69D 3FDJA 3QVDA 4AI1A 1BFYA 5IYCL 5C44L 2MS3A 2E2JL 1DVBA 4A3ML 4POFA 1YV1A 5M3FL 1C09A 5C4JL 3HOYL 5GAEc 5IP7L 4V196 1PFWA 2Z3QB 2PVXA 5GAHc 3RZOL 3QQCE 2A6ED 4A3KL 3HOUL 1IU6A 5C3EL 1WCML 2M6OA 5C4XL 5IYDL 1K83L 2QL0A 4ZN1B 3ZG6A 2NVTL 2YU9L 1R0FA 2KN9A 1S24A 1YUXA 4A93L 4JAFA 3NFPI 2PPTA 4YWLA 3GTLL 1T9PA 1PFVA 4C3JL 3S1NL 2XJQA 1B2OA 3S1ML 2RDVA 1H7VA 1VZIA 2WAQP 1R9TL 1DX8A 3J7Y1 5GADc 2R93L 2M6PA 2PMZP 2JA7L 1R0JA 4GS7D 4POGA 3S16L 8RXNA 3WWNB 3RZ6A 3S1QL 1NNQA 3K7AL 2L0ZA 1BQ8A 1ZRPA 5MGNA 2ZIXA 3GTPL 3KYWA 5K2ME 4AI3A 1TWFL 1JYBA 1R0HA 2XJRA 1TWHL 4AR6A 1T9QA 3I4NL 1SMUA 4A3JL 1Y1VL 2JA6L 4AR4A 3FKIL 1TWGL 5JVG1 3GTQL 1P7PA 3LWPB 4YWMA 1IRNA 3LNLA 4X6AL 3GTJL 2JA8L 3S14L 1FHMA 4A3GL 2XJPA 3KYVA 4A3IL 3VPBE 2K2DA 1I6HL 7RXNA 4AHWA 4BXXL 2R92L 5EINC 4LHLA 5IYBL 4C3HL 2BE5D 1PFYA 3GTML 2HR5A 3J7Z1 1QQTA 3S2DL 3MPSA 4AI2A 2CKAA 1PFUA 2XJUA 5MF6A 3S1RL 4BY7L 1E8JA 3RZTA 2RFKB 2B63L 4A3LL 4UY81 1LTLA 4JAGA 4AHYA 1CADA 4QIWP 1TWAL 2AYJA 3H9BA 3GTOL 4LHNA 4BBRL 2WB1P 5H1Sc 2AQCA 2JI1A 3H0GL 1BRFA 3CQZL 2XJVA 3A44A 2XJSA 3B0AB 4AR5A 2APOB 2CR8A 2KKDA 1VCXA 1YK5A 2XJTA 2NVQL 4U671 4JADA 2JI2A 2E2HL 1WJVA 2A6HD 4TVMA 1OWBA 1Z92B 4WFN1 3I4ML 2ERJA 3H97A 1RWDA 3PZAA 2NYDA 5DM61 2Z3RB 1FHHA 3S15L 2JA5L 1B13A 3M4OL 2ERSA 4C3IL 4K9FA 5M5YL 2A68D 3HOXL 3B08B 5M5XL 3KYXA 2VL6A 5IY0A 1YUZA 4AHXA 1LKOA 4A3FL 5EIOC 3PKIA 4TPUA 1IW7D 3RYGA 5DM71 1CAAA 4C2M1 3KYYA 5MFPA 4ZN3B 1Y1WL 2B5ID 3PKJA 3M3YL 2PSMC 2VUML 1B2JA 3RZDL 3LPEB 2V0FA 4A3CL 3HOVL 2M4VA 5AI2A 2GMGA 4AHZA 4Y7NL 4A3EL 1S2ZA 1VZGA 3WWLA 2R7ZL 3PIP1 1S30A 3P8BA 1ODHA 3GTKL 3MSUA 2O5JD 1I3QL 1PZXA 2V3BB 2HVYC 3LWQB 4RXNA 3KYUA 2DSXA 2C6BA 5IP9L 3GTGL 1B71A 5M5WL 3HOWL 3LWVB 1RB9A 3P2AA 5MLC3 2NVXL 3LWOB 2EY4E 1F4LA 5MFZA 4AYBP 3SS2A 1SMMA 4G6BA 2CKCA 1NXEA 1I50L 1OWCA 3HKZP 3S2HL 4XGHA 1VZHA 3H3VM 3H9CA 5FJ8L 3PIO1 1SMWA 3S17L 4BBSL 4E6YA 5M3ML 1RYTA 1LKPA 1R0IA 1QCVA 2V0EA 1IROA 1BQ9A 2E2IL 3HJWB 5AI3A 4BY1L 4AI0A 2AUSB 6RXNA 3LWRB 4JAEA 2PYAA 5GAGc 3MQKB
chains in the Genus database with same CATH topology
5IYBL 5FLML 4C3HL 4A3FL 3GTML 4A93L 3S2DL 3GTLL 3PO3L 4C3JL 3S1NL 4C2M1 3S1RL 4BY7L 4Y52L 3S1ML 2B63L 2WAQP 1Y1WL 1R9TL 4A3LL 3M3YL 2VUML 2R93L 3RZDL 4A3CL 3HOVL 2PMZP 2JA7L 3HOZL 4Y7NL 4A3EL 4A3BL 2Y0SP 3S16L 4QIWP 2R7ZL 1TWAL 3GTKL 3GTOL 3S1QL 3K7AL 1TWCL 1I3QL 4BBRL 2WB1P 4A3DL 3GTPL 3H0GL 5IP9L 3GTGL 3CQZL 3PO2L 1SFOL 5M5WL 3HOWL 2NVYL 2NVXL 1TWFL 4AYBP 1TWHL 1I50L 3I4NL 3HKZP 4A3JL 5IYCL 3S2HL 1Y1VL 2NVQL 2JA6L 5C44L 3FKIL 1TWGL 3GTQL 3H3VM 2E2JL 5FJ8L 2E2HL 3S17L 4A3ML 4BBSL 4BXXL 5M3ML 5M3FL 5C4JL 3HOYL 5IP7L 3I4ML 4X6AL 3GTJL 3RZOL 3S15L 2JA8L 3S14L 2JA5L 2E2IL 4A3KL 3HOUL 3M4OL 4A3GL 5C3EL 4C3IL 4BY1L 1WCML 4A3IL 5C4XL 5M5YL 5IYDL 1K83L 1I6HL 3HOXL 5M5XL 2NVTL 2YU9L 2R92L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IYB L;  5FLM L;  4C3H L;  4A3F L;  3GTM L;  4A93 L;  3S2D L;  3GTL L;  3PO3 L;  4C3J L;  3S1N L;  4C2M 1;  3S1R L;  4BY7 L;  4Y52 L;  3S1M L;  2B63 L;  2WAQ P;  1Y1W L;  1R9T L;  4A3L L;  3M3Y L;  2VUM L;  2R93 L;  3RZD L;  4A3C L;  3HOV L;  2PMZ P;  2JA7 L;  3HOZ L;  4Y7N L;  4A3E L;  4A3B L;  2Y0S P;  3S16 L;  4QIW P;  2R7Z L;  1TWA L;  3GTK L;  3GTO L;  3S1Q L;  3K7A L;  1TWC L;  1I3Q L;  4BBR L;  2WB1 P;  4A3D L;  3GTP L;  3H0G L;  5IP9 L;  3GTG L;  3CQZ L;  3PO2 L;  1SFO L;  5M5W L;  3HOW L;  2NVY L;  2NVX L;  1TWF L;  4AYB P;  1TWH L;  1I50 L;  3I4N L;  3HKZ P;  4A3J L;  5IYC L;  3S2H L;  1Y1V L;  2NVQ L;  2JA6 L;  5C44 L;  3FKI L;  1TWG L;  3GTQ L;  3H3V M;  2E2J L;  5FJ8 L;  2E2H L;  3S17 L;  4A3M L;  4BBS L;  4BXX L;  5M3M L;  5M3F L;  5C4J L;  3HOY L;  5IP7 L;  3I4M L;  4X6A L;  3GTJ L;  3RZO L;  3S15 L;  2JA8 L;  3S14 L;  2JA5 L;  2E2I L;  4A3K L;  3HOU L;  3M4O L;  4A3G L;  5C3E L;  4C3I L;  4BY1 L;  1WCM L;  4A3I L;  5C4X L;  5M5Y L;  5IYD L;  1K83 L;  1I6H L;  3HOX L;  5M5X L;  2NVT L;  2YU9 L;  2R92 L; 
#chains in the Genus database with same CATH topology
 5FLM L;  1BE7 A;  1LKM A;  1RDG A;  3PO3 L;  1T9O A;  3PL5 A;  3IU3 I;  3HAX C;  3HJY B;  1IU5 A;  4Y52 L;  1RYQ A;  1R0G A;  4AR3 A;  2M4Y A;  3JR7 A;  5JVH 1;  3HOZ L;  4A3B L;  2Y0S P;  2PVE A;  1RDV A;  1TWC L;  2JI3 A;  4A3D L;  2C6A A;  1QYB A;  1NXG A;  3PO2 L;  1SFO L;  2NVY L;  2J9U B;  4B8C D;  4XXB B;  5RXN A;  5AN9 H;  2LCQ A;  3K35 A;  4ME3 A;  3H99 A;  2H12 A;  1YK4 A;  3PWF A;  2A69 D;  3FDJ A;  3QVD A;  4AI1 A;  1BFY A;  5IYC L;  5C44 L;  2MS3 A;  2E2J L;  1DVB A;  4A3M L;  4POF A;  1YV1 A;  5M3F L;  1C09 A;  5C4J L;  3HOY L;  5GAE c;  5IP7 L;  4V19 6;  1PFW A;  2Z3Q B;  2PVX A;  5GAH c;  3RZO L;  3QQC E;  2A6E D;  4A3K L;  3HOU L;  1IU6 A;  5C3E L;  1WCM L;  2M6O A;  5C4X L;  5IYD L;  1K83 L;  2QL0 A;  4ZN1 B;  3ZG6 A;  2NVT L;  2YU9 L;  1R0F A;  2KN9 A;  1S24 A;  1YUX A;  4A93 L;  4JAF A;  3NFP I;  2PPT A;  4YWL A;  3GTL L;  1T9P A;  1PFV A;  4C3J L;  3S1N L;  2XJQ A;  1B2O A;  3S1M L;  2RDV A;  1H7V A;  1VZI A;  2WAQ P;  1R9T L;  1DX8 A;  3J7Y 1;  5GAD c;  2R93 L;  2M6P A;  2PMZ P;  2JA7 L;  1R0J A;  4GS7 D;  4POG A;  3S16 L;  8RXN A;  3WWN B;  3RZ6 A;  3S1Q L;  1NNQ A;  3K7A L;  2L0Z A;  1BQ8 A;  1ZRP A;  5MGN A;  2ZIX A;  3GTP L;  3KYW A;  5K2M E;  4AI3 A;  1TWF L;  1JYB A;  1R0H A;  2XJR A;  1TWH L;  4AR6 A;  1T9Q A;  3I4N L;  1SMU A;  4A3J L;  1Y1V L;  2JA6 L;  4AR4 A;  3FKI L;  1TWG L;  5JVG 1;  3GTQ L;  1P7P A;  3LWP B;  4YWM A;  1IRN A;  3LNL A;  4X6A L;  3GTJ L;  2JA8 L;  3S14 L;  1FHM A;  4A3G L;  2XJP A;  3KYV A;  4A3I L;  3VPB E;  2K2D A;  1I6H L;  7RXN A;  4AHW A;  4BXX L;  2R92 L;  5EIN C;  4LHL A;  5IYB L;  4C3H L;  2BE5 D;  1PFY A;  3GTM L;  2HR5 A;  3J7Z 1;  1QQT A;  3S2D L;  3MPS A;  4AI2 A;  2CKA A;  1PFU A;  2XJU A;  5MF6 A;  3S1R L;  4BY7 L;  1E8J A;  3RZT A;  2RFK B;  2B63 L;  4A3L L;  4UY8 1;  1LTL A;  4JAG A;  4AHY A;  1CAD A;  4QIW P;  1TWA L;  2AYJ A;  3H9B A;  3GTO L;  4LHN A;  4BBR L;  2WB1 P;  5H1S c;  2AQC A;  2JI1 A;  3H0G L;  1BRF A;  3CQZ L;  2XJV A;  3A44 A;  2XJS A;  3B0A B;  4AR5 A;  2APO B;  2CR8 A;  2KKD A;  1VCX A;  1YK5 A;  2XJT A;  2NVQ L;  4U67 1;  4JAD A;  2JI2 A;  2E2H L;  1WJV A;  2A6H D;  4TVM A;  1OWB A;  1Z92 B;  4WFN 1;  3I4M L;  2ERJ A;  3H97 A;  1RWD A;  3PZA A;  2NYD A;  5DM6 1;  2Z3R B;  1FHH A;  3S15 L;  2JA5 L;  1B13 A;  3M4O L;  2ERS A;  4C3I L;  4K9F A;  5M5Y L;  2A68 D;  3HOX L;  3B08 B;  5M5X L;  3KYX A;  2VL6 A;  5IY0 A;  1YUZ A;  4AHX A;  1LKO A;  4A3F L;  5EIO C;  3PKI A;  4TPU A;  1IW7 D;  3RYG A;  5DM7 1;  1CAA A;  4C2M 1;  3KYY A;  5MFP A;  4ZN3 B;  1Y1W L;  2B5I D;  3PKJ A;  3M3Y L;  2PSM C;  2VUM L;  1B2J A;  3RZD L;  3LPE B;  2V0F A;  4A3C L;  3HOV L;  2M4V A;  5AI2 A;  2GMG A;  4AHZ A;  4Y7N L;  4A3E L;  1S2Z A;  1VZG A;  3WWL A;  2R7Z L;  3PIP 1;  1S30 A;  3P8B A;  1ODH A;  3GTK L;  3MSU A;  2O5J D;  1I3Q L;  1PZX A;  2V3B B;  2HVY C;  3LWQ B;  4RXN A;  3KYU A;  2DSX A;  2C6B A;  5IP9 L;  3GTG L;  1B71 A;  5M5W L;  3HOW L;  3LWV B;  1RB9 A;  3P2A A;  5MLC 3;  2NVX L;  3LWO B;  2EY4 E;  1F4L A;  5MFZ A;  4AYB P;  3SS2 A;  1SMM A;  4G6B A;  2CKC A;  1NXE A;  1I50 L;  1OWC A;  3HKZ P;  3S2H L;  4XGH A;  1VZH A;  3H3V M;  3H9C A;  5FJ8 L;  3PIO 1;  1SMW A;  3S17 L;  4BBS L;  4E6Y A;  5M3M L;  1RYT A;  1LKP A;  1R0I A;  1QCV A;  2V0E A;  1IRO A;  1BQ9 A;  2E2I L;  3HJW B;  5AI3 A;  4BY1 L;  4AI0 A;  2AUS B;  6RXN A;  3LWR B;  4JAE A;  2PYA A;  5GAG c;  3MQK B; 
#chains in the Genus database with same CATH homology
 5IYB L;  5FLM L;  4C3H L;  4A3F L;  3GTM L;  4A93 L;  3S2D L;  3GTL L;  3PO3 L;  4C3J L;  3S1N L;  4C2M 1;  3S1R L;  4BY7 L;  4Y52 L;  3S1M L;  2B63 L;  2WAQ P;  1Y1W L;  1R9T L;  4A3L L;  3M3Y L;  2VUM L;  2R93 L;  3RZD L;  4A3C L;  3HOV L;  2PMZ P;  2JA7 L;  3HOZ L;  4Y7N L;  4A3E L;  4A3B L;  2Y0S P;  3S16 L;  4QIW P;  2R7Z L;  1TWA L;  3GTK L;  3GTO L;  3S1Q L;  3K7A L;  1TWC L;  1I3Q L;  4BBR L;  2WB1 P;  4A3D L;  3GTP L;  3H0G L;  5IP9 L;  3GTG L;  3CQZ L;  3PO2 L;  1SFO L;  5M5W L;  3HOW L;  2NVY L;  2NVX L;  1TWF L;  4AYB P;  1TWH L;  1I50 L;  3I4N L;  3HKZ P;  4A3J L;  5IYC L;  3S2H L;  1Y1V L;  2NVQ L;  2JA6 L;  5C44 L;  3FKI L;  1TWG L;  3GTQ L;  3H3V M;  2E2J L;  5FJ8 L;  2E2H L;  3S17 L;  4A3M L;  4BBS L;  4BXX L;  5M3M L;  5M3F L;  5C4J L;  3HOY L;  5IP7 L;  3I4M L;  4X6A L;  3GTJ L;  3RZO L;  3S15 L;  2JA8 L;  3S14 L;  2JA5 L;  2E2I L;  4A3K L;  3HOU L;  3M4O L;  4A3G L;  5C3E L;  4C3I L;  4BY1 L;  1WCM L;  4A3I L;  5C4X L;  5M5Y L;  5IYD L;  1K83 L;  1I6H L;  3HOX L;  5M5X L;  2NVT L;  2YU9 L;  2R92 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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