The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
105
|
sequence length |
296
|
structure length |
296
|
Chain Sequence |
MGSLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule tags |
Hydrolase
|
| source organism |
Homo sapiens
|
| publication title |
Structural and Functional Analysis of the GADD34:PP1 eIF2 alpha Phosphatase.
pubmed doi rcsb |
| molecule keywords |
Serine/threonine-protein phosphatase PP1-alpha catalytic sub
|
| total genus |
105
|
| structure length |
296
|
| sequence length |
296
|
| chains with identical sequence |
C
|
| ec nomenclature |
ec
3.1.3.16: Protein-serine/threonine phosphatase. |
| pdb deposition date | 2015-01-17 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00149 | Metallophos | Calcineurin-like phosphoesterase |
| A | PF16891 | STPPase_N | Serine-threonine protein phosphatase N-terminal domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 4-Layer Sandwich | Purple Acid Phosphatase; chain A, domain 2 | Purple Acid Phosphatase; chain A, domain 2 |
#chains in the Genus database with same CATH superfamily 3C5W C; 1II7 A; 2HYP A; 2KKN A; 3C9F A; 4H1Y P; 5JPE A; 4J6O A; 1S3M A; 1XM7 A; 4JA9 A; 2O8A A; 4V0X A; 4H2F A; 4DSY A; 2NYM C; 2QFP A; 4H2B A; 4JA7 A; 1NNW A; 3HVQ A; 1S70 A; 3CK2 A; 3H69 A; 3DSD A; 2O8G A; 3QFO A; 1OIE A; 3KBP A; 4O4K A; 3AV0 A; 4IYP C; 1S8E A; 4UT3 B; 2Q8U A; 5DNY A; 3H66 A; 1M63 A; 3LL8 A; 2NPP C; 3H64 A; 3AUZ A; 3QG5 C; 3H60 A; 3ZTV A; 4I5L C; 4LU9 A; 5IOH A; 1OID A; 3RL3 A; 4YKE A; 3ICF A; 4OR9 A; 4ORB A; 1MF8 A; 2AHD A; 4Q7F A; 1Z2W A; 4FCX A; 4MOY A; 4DT2 A; 1U32 A; 2XMO A; 3IB8 A; 3THN A; 5EQV A; 1W24 A; 3N5U A; 1QHW A; 1V73 A; 3E7B A; 4I5N C; 5JJT A; 4FBQ A; 4V0V A; 2P6B A; 2WDD A; 4UWQ A; 3DSC A; 2HYO A; 2A22 A; 3RQZ A; 1AUI A; 3FGA C; 4F0Z A; 1S3L A; 4H1S A; 4UT2 A; 4ZVZ A; 1XZW A; 1HO5 A; 4TUI A; 3EGG A; 3IVD A; 1T70 A; 3DW8 C; 4MP0 A; 4ORC A; 2WDE A; 3H67 A; 4FBW A; 4G9J A; 3PSN A; 3PSO A; 4M0V A; 2IE3 C; 4O43 A; 4ZX2 A; 5GTU A; 2JOG A; 3IVE A; 3H61 A; 2YVT A; 5HPE A; 1USH A; 4IL1 A; 1TCO A; 3IB7 A; 4MOV A; 4TUG A; 4XPN A; 3QFN A; 3EGH A; 4B2O A; 1SU1 A; 2QJC A; 4UT3 A; 1UF3 A; 3RL5 A; 5C1V A; 1FJM A; 1S95 A; 2GJU A; 2DFJ A; 2IE4 C; 5B8I A; 2NYL C; 2QFR A; 3K7W C; 3QFM A; 2Z72 A; 1JK7 A; 1WAO 1; 2IAE C; 1IT6 A; 1KBP A; 3QFK A; 4LTY A; 1QFC A; 3K7V C; 1OI8 A; 5INB A; 1T71 A; 3H68 A; 4DHL A; 2BQ8 X; 4O5G A; 4FBK A; 3E7A A; 5J28 A; 3TGH A; 2ZBM A; 4O24 A; 2R17 A; 3H63 A; 2CV9 A; 3THO B; 5JPF A; 2HY1 A; 1S3N A; 2USH A; 4ORA A; 4NZV A; 3RL4 A; 3ZU0 A; 4KKZ A; 4V0W A; 2BDX A; 3JYF A; 3H62 B; 1UTE A; 2Z06 A; 4H2I A; 3GVE A; 1HPU A; 3T1I A; 1HP1 A; 3V4Y A; 4WWL A; 2WDF A; 5F3W A; 1G5B A; 2NXF A; 4KBP A; 1Z2X A; 4HD0 A; 3P71 C; 2WDC A; 4LAC C; 2Z1A A; 4H2G A; 1WAR A; 2BCD A; #chains in the Genus database with same CATH topology 3C5W C; 1II7 A; 2HYP A; 2KKN A; 3C9F A; 4H1Y P; 5JPE A; 4J6O A; 1S3M A; 1XM7 A; 4JA9 A; 2O8A A; 4V0X A; 4H2F A; 4DSY A; 2NYM C; 2QFP A; 4H2B A; 4JA7 A; 1NNW A; 3HVQ A; 1S70 A; 3CK2 A; 3H69 A; 3DSD A; 2O8G A; 3QFO A; 1OIE A; 3KBP A; 4O4K A; 3AV0 A; 4IYP C; 1S8E A; 4UT3 B; 2Q8U A; 5DNY A; 3H66 A; 1M63 A; 3LL8 A; 2NPP C; 3H64 A; 3AUZ A; 3QG5 C; 3H60 A; 3ZTV A; 4I5L C; 4LU9 A; 5IOH A; 1OID A; 3RL3 A; 4YKE A; 3E0J A; 3ICF A; 2DXN A; 4OR9 A; 4ORB A; 1MF8 A; 2AHD A; 4Q7F A; 1Z2W A; 4FCX A; 3D03 A; 4MOY A; 4DT2 A; 1U32 A; 2XMO A; 3IB8 A; 3THN A; 5EQV A; 1W24 A; 3N5U A; 1QHW A; 1V73 A; 3E7B A; 2ZO9 B; 4I5N C; 5JJT A; 4FBQ A; 4V0V A; 2P6B A; 2WDD A; 4UWQ A; 3DSC A; 2HYO A; 2A22 A; 3RQZ A; 1AUI A; 2DXL A; 3FGA C; 4F0Z A; 1S3L A; 4H1S A; 4UT2 A; 4ZVZ A; 1XZW A; 1HO5 A; 4TUI A; 3EGG A; 3IVD A; 1T70 A; 3DW8 C; 4MP0 A; 4ORC A; 2WDE A; 3H67 A; 4FBW A; 4G9J A; 3PSN A; 3PSO A; 4M0V A; 2IE3 C; 4O43 A; 4ZX2 A; 5GTU A; 2JOG A; 3IVE A; 3H61 A; 2YVT A; 5HPE A; 1USH A; 4IL1 A; 1TCO A; 3IB7 A; 4MOV A; 4TUG A; 4XPN A; 3QFN A; 2ZOA A; 3EGH A; 4B2O A; 1SU1 A; 2QJC A; 4UT3 A; 1UF3 A; 3RL5 A; 5C1V A; 1FJM A; 1S95 A; 2GJU A; 2DFJ A; 2IE4 C; 5B8I A; 2NYL C; 2QFR A; 3K7W C; 3QFM A; 2Z72 A; 1JK7 A; 1WAO 1; 2IAE C; 1IT6 A; 1KBP A; 3QFK A; 4LTY A; 1QFC A; 3K7V C; 1OI8 A; 5INB A; 1T71 A; 3H68 A; 4DHL A; 2BQ8 X; 4O5G A; 4FBK A; 3E7A A; 5J28 A; 3TGH A; 2ZBM A; 4O24 A; 2R17 A; 3H63 A; 2CV9 A; 3THO B; 5JPF A; 2HY1 A; 1S3N A; 2USH A; 4ORA A; 4NZV A; 3RL4 A; 3ZU0 A; 4KKZ A; 4V0W A; 2BDX A; 3JYF A; 3H62 B; 1UTE A; 2Z06 A; 2YEQ A; 4H2I A; 3GVE A; 1HPU A; 3T1I A; 1HP1 A; 3V4Y A; 4WWL A; 2WDF A; 3FLO A; 1G5B A; 2NXF A; 4KBP A; 5F3W A; 1Z2X A; 4HD0 A; 3P71 C; 2WDC A; 4LAC C; 2Z1A A; 4H2G A; 1WAR A; 2BCD A; #chains in the Genus database with same CATH homology 3C5W C; 1II7 A; 2HYP A; 2KKN A; 3C9F A; 4H1Y P; 5JPE A; 4J6O A; 1S3M A; 1XM7 A; 4JA9 A; 2O8A A; 4V0X A; 4H2F A; 4DSY A; 2NYM C; 2QFP A; 4H2B A; 4JA7 A; 1NNW A; 3HVQ A; 1S70 A; 3CK2 A; 3H69 A; 3DSD A; 2O8G A; 3QFO A; 1OIE A; 3KBP A; 4O4K A; 3AV0 A; 4IYP C; 1S8E A; 4UT3 B; 2Q8U A; 5DNY A; 3H66 A; 1M63 A; 3LL8 A; 2NPP C; 3H64 A; 3AUZ A; 3QG5 C; 3H60 A; 3ZTV A; 4I5L C; 4LU9 A; 5IOH A; 1OID A; 3RL3 A; 4YKE A; 3E0J A; 3ICF A; 2DXN A; 4OR9 A; 4ORB A; 1MF8 A; 2AHD A; 4Q7F A; 1Z2W A; 4FCX A; 3D03 A; 4MOY A; 4DT2 A; 1U32 A; 2XMO A; 3IB8 A; 3THN A; 5EQV A; 1W24 A; 3N5U A; 1QHW A; 1V73 A; 3E7B A; 2ZO9 B; 4I5N C; 5JJT A; 4FBQ A; 4V0V A; 2P6B A; 2WDD A; 4UWQ A; 3DSC A; 2HYO A; 2A22 A; 3RQZ A; 1AUI A; 2DXL A; 3FGA C; 4F0Z A; 1S3L A; 4H1S A; 4UT2 A; 4ZVZ A; 1XZW A; 1HO5 A; 4TUI A; 3EGG A; 3IVD A; 1T70 A; 3DW8 C; 4MP0 A; 4ORC A; 2WDE A; 3H67 A; 4FBW A; 4G9J A; 3PSN A; 3PSO A; 4M0V A; 2IE3 C; 4O43 A; 4ZX2 A; 5GTU A; 2JOG A; 3IVE A; 3H61 A; 2YVT A; 5HPE A; 1USH A; 4IL1 A; 1TCO A; 3IB7 A; 4MOV A; 4TUG A; 4XPN A; 3QFN A; 2ZOA A; 3EGH A; 4B2O A; 1SU1 A; 2QJC A; 4UT3 A; 1UF3 A; 3RL5 A; 5C1V A; 1FJM A; 1S95 A; 2GJU A; 2DFJ A; 2IE4 C; 5B8I A; 2NYL C; 2QFR A; 3K7W C; 3QFM A; 2Z72 A; 1JK7 A; 1WAO 1; 2IAE C; 1IT6 A; 1KBP A; 3QFK A; 4LTY A; 1QFC A; 3K7V C; 1OI8 A; 5INB A; 1T71 A; 3H68 A; 4DHL A; 2BQ8 X; 4O5G A; 4FBK A; 3E7A A; 5J28 A; 3TGH A; 2ZBM A; 4O24 A; 2R17 A; 3H63 A; 2CV9 A; 3THO B; 5JPF A; 2HY1 A; 1S3N A; 2USH A; 4ORA A; 4NZV A; 3RL4 A; 3ZU0 A; 4KKZ A; 4V0W A; 2BDX A; 3JYF A; 3H62 B; 1UTE A; 2Z06 A; 2YEQ A; 4H2I A; 3GVE A; 1HPU A; 3T1I A; 1HP1 A; 3V4Y A; 4WWL A; 2WDF A; 3FLO A; 1G5B A; 2NXF A; 4KBP A; 5F3W A; 1Z2X A; 4HD0 A; 3P71 C; 2WDC A; 4LAC C; 2Z1A A; 4H2G A; 1WAR A; 2BCD A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
