4A3DL

Rna polymerase ii initial transcribing complex with a 6nt dna-rna hybrid
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4a3dL00
4C3IL 5M3ML 3RZOL 3S1ML 3HOXL 4A3GL 4A3DL 3GTGL 2B63L 3RZDL 2NVXL 3K7AL 2R92L 1I6HL 3HOYL 4C3JL 3S1QL 4X6AL 4A3KL 2Y0SP 3FKIL 3GTLL 4BBSL 5M3FL 3GTML 5IYCL 4QIWP 3S17L 5FLML 2JA8L 1TWHL 4A3LL 5M5XL 2JA6L 4C3HL 2NVTL 1K83L 2JA5L 4A3JL 5IYBL 4Y52L 1TWFL 3GTKL 2R7ZL 5M5YL 1SFOL 1I50L 4BY7L 1TWAL 4C2M1 3HKZP 5IYDL 5M5WL 3I4NL 4BY1L 3I4ML 5IP7L 3S16L 3H0GL 4A93L 3GTOL 3HOWL 3M3YL 2WB1P 3GTQL 3S15L 3M4OL 2NVYL 3S1NL 3S1RL 5C4JL 2NVQL 3HOZL 5FJ8L 2E2JL 3H3VM 4A3FL 4A3IL 2JA7L 3HOVL 2YU9L 5C4XL 2WAQP 2E2IL 2E2HL 4A3ML 4AYBP 3PO2L 5C44L 3S14L 3CQZL 3GTJL 4Y7NL 2VUML 1WCML 3S2DL 3S2HL 1Y1VL 4A3CL 5C3EL 1TWGL 2PMZP 1R9TL 5IP9L 4BBRL 3PO3L 1TWCL 3GTPL 3HOUL 4A3EL 4A3BL 1I3QL 1Y1WL 2R93L 4BXXL
chains in the Genus database with same CATH superfamily
1R0GA 3GTGL 3HJWB 2A69D 2O5JD 4GS7D 3VPBE 5MGNA 1QCVA 3GTLL 1VZIA 4BBSL 5DM61 5IYCL 2PVEA 4QIWP 2V0EA 4LHLA 2JA8L 5AI3A 1BQ8A 1TWHL 2NYDA 1OWBA 3LNLA 4ZN1B 4A3LL 1RDVA 1S30A 2R7ZL 1RYQA 3MQKB 1IRNA 4JAGA 2K2DA 5IYDL 2CR8A 5IP7L 4A93L 1T9QA 3GTQL 2B5ID 2KN9A 2XJQA 4XXBB 1NXGA 3S1NL 3PZAA 3PL5A 4V196 1SMWA 4JADA 1RDGA 1YV1A 3H3VM 1PFYA 4A3IL 2JA7L 1OWCA 2PSMC 2RFKB 1LTLA 1B71A 2VUML 4B8CD 2APOB 3J7Z1 3S2DL 2Z3QB 1TWGL 4AR5A 1R9TL 5GADc 2JI1A 5EINC 1IU6A 1S2ZA 5AN9H 4G6BA 3PO3L 1TWCL 4A3EL 1RWDA 2AQCA 6RXNA 2C6AA 2QL0A 5DM71 3WWNB 5M3ML 3B0AB 4A3GL 3KYXA 3RZDL 1CAAA 1E8JA 2XJUA 3P8BA 1B13A 1IU5A 4C3JL 2M6PA 2V3BB 2HVYC 1PFUA 3PIP1 1PZXA 1DX8A 2M4YA 1LKMA 4WFN1 1FHMA 1YUXA 4POFA 3MSUA 2V0FA 5M5XL 1P7PA 4C3HL 2NVTL 4A3JL 1YK5A 5GAEc 4TVMA 4TPUA 2AUSB 4Y52L 3GTKL 1B2OA 4AI3A 8RXNA 3I4NL 4BY1L 2BE5D 4LHNA 3S16L 3LWRB 5MFPA 1R0JA 3M4OL 1SMMA 2AYJA 5IY0A 3IU3I 4UY81 5MF6A 3H9CA 4POGA 2E2JL 2XJTA 1F4LA 5C4XL 2XJVA 2E2IL 1LKOA 4AYBP 3KYWA 1RYTA 3GTJL 4RXNA 4ZN3B 4A3CL 1NNQA 2PMZP 3LWPB 1BE7A 2PYAA 4AHXA 1VCXA 2H12A 3KYYA 4AI0A 1I3QL 2ERSA 4BXXL 3LWVB 4C3IL 3KYVA 3HOXL 4A3DL 1NXEA 5AI2A 1VZGA 2C6BA 4AR4A 2NVXL 3K7AL 1I6HL 3HOYL 4X6AL 3S1QL 2LCQA 7RXNA 1JYBA 2Y0SP 1PFVA 4AHYA 3RYGA 3GTML 3S17L 3KYUA 1S24A 1PFWA 3JR7A 4YWMA 2JA6L 2JA5L 1YUZA 5IYBL 2MS3A 5M5YL 3QVDA 1SFOL 5GAGc 2L0ZA 3H99A 1R0HA 4C2M1 1ODHA 3SS2A 5EIOC 5M5WL 3PKIA 1T9OA 2A68D 3PIO1 3M3YL 2A6HD 2RDVA 1WJVA 3S1RL 1R0IA 2M6OA 5C4JL 3HOZL 2CKAA 2XJPA 4AHWA 3HOVL 2KKDA 5JVG1 3WWLA 5RXNA 2J9UB 5MFZA 3HAXC 4AI1A 5C44L 5GAHc 3HJYB 3S14L 4Y7NL 1WCML 1Y1VL 2GMGA 5C3EL 1FHHA 3NFPI 3P2AA 5IP9L 1IROA 2DSXA 3GTPL 3HOUL 1R0FA 1BRFA 3FDJA 2R93L 3PKJA 3RZTA 2Z3RB 1YK4A 4JAEA 4AI2A 3RZOL 2VL6A 3S1ML 2B63L 1SMUA 2ZIXA 2XJRA 2R92L 3ZG6A 1C09A 1LKPA 1H7VA 1VZHA 4A3KL 2EY4E 2XJSA 2JI3A 3FKIL 2PPTA 5M3FL 3PWFA 5FLML 1BQ9A 3H97A 3LWOB 1ZRPA 4E6YA 1K83L 1TWFL 1Z92B 3J7Y1 2A6ED 3RZ6A 1I50L 4BY7L 1TWAL 3HKZP 2JI2A 1IW7D 3I4ML 2M4VA 1QYBA 1QQTA 3H0GL 1B2JA 3GTOL 3HOWL 2WB1P 3S15L 2ERJA 2NVYL 3K35A 3B08B 3MPSA 5JVH1 2NVQL 5FJ8L 3LPEB 4AHZA 3LWQB 1RB9A 4A3FL 2CKCA 3QQCE 5H1Sc 1BFYA 2YU9L 2WAQP 2E2HL 1DVBA 2PVXA 3A44A 5MLC3 4A3ML 4XGHA 3PO2L 3CQZL 3S2HL 2HR5A 4AR3A 5K2ME 4BBRL 4AR6A 4JAFA 3H9BA 1T9PA 4A3BL 4ME3A 4K9FA 1CADA 4YWLA 4U671 1Y1WL
chains in the Genus database with same CATH topology
4C3IL 5M3ML 3RZOL 3S1ML 3HOXL 4A3GL 4A3DL 3GTGL 2B63L 3RZDL 2NVXL 3K7AL 2R92L 1I6HL 3HOYL 4C3JL 3S1QL 4X6AL 4A3KL 2Y0SP 3FKIL 3GTLL 4BBSL 5M3FL 3GTML 5IYCL 4QIWP 3S17L 5FLML 2JA8L 1TWHL 4A3LL 5M5XL 2JA6L 4C3HL 2NVTL 1K83L 2JA5L 4A3JL 5IYBL 4Y52L 1TWFL 3GTKL 2R7ZL 5M5YL 1SFOL 1I50L 4BY7L 1TWAL 4C2M1 3HKZP 5IYDL 5M5WL 3I4NL 4BY1L 3I4ML 5IP7L 3S16L 3H0GL 4A93L 3GTOL 3HOWL 3M3YL 2WB1P 3GTQL 3S15L 3M4OL 2NVYL 3S1NL 3S1RL 5C4JL 2NVQL 3HOZL 5FJ8L 2E2JL 3H3VM 4A3FL 4A3IL 2JA7L 3HOVL 2YU9L 5C4XL 2WAQP 2E2IL 2E2HL 4A3ML 4AYBP 3PO2L 5C44L 3S14L 3CQZL 3GTJL 4Y7NL 2VUML 1WCML 3S2DL 3S2HL 1Y1VL 4A3CL 5C3EL 1TWGL 2PMZP 1R9TL 5IP9L 4BBRL 3PO3L 1TWCL 3GTPL 3HOUL 4A3EL 4A3BL 1I3QL 1Y1WL 2R93L 4BXXL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C3I L;  5M3M L;  3RZO L;  3S1M L;  3HOX L;  4A3G L;  4A3D L;  3GTG L;  2B63 L;  3RZD L;  2NVX L;  3K7A L;  2R92 L;  1I6H L;  3HOY L;  4C3J L;  3S1Q L;  4X6A L;  4A3K L;  2Y0S P;  3FKI L;  3GTL L;  4BBS L;  5M3F L;  3GTM L;  5IYC L;  4QIW P;  3S17 L;  5FLM L;  2JA8 L;  1TWH L;  4A3L L;  5M5X L;  2JA6 L;  4C3H L;  2NVT L;  1K83 L;  2JA5 L;  4A3J L;  5IYB L;  4Y52 L;  1TWF L;  3GTK L;  2R7Z L;  5M5Y L;  1SFO L;  1I50 L;  4BY7 L;  1TWA L;  4C2M 1;  3HKZ P;  5IYD L;  5M5W L;  3I4N L;  4BY1 L;  3I4M L;  5IP7 L;  3S16 L;  3H0G L;  4A93 L;  3GTO L;  3HOW L;  3M3Y L;  2WB1 P;  3GTQ L;  3S15 L;  3M4O L;  2NVY L;  3S1N L;  3S1R L;  5C4J L;  2NVQ L;  3HOZ L;  5FJ8 L;  2E2J L;  3H3V M;  4A3F L;  4A3I L;  2JA7 L;  3HOV L;  2YU9 L;  5C4X L;  2WAQ P;  2E2I L;  2E2H L;  4A3M L;  4AYB P;  3PO2 L;  5C44 L;  3S14 L;  3CQZ L;  3GTJ L;  4Y7N L;  2VUM L;  1WCM L;  3S2D L;  3S2H L;  1Y1V L;  4A3C L;  5C3E L;  1TWG L;  2PMZ P;  1R9T L;  5IP9 L;  4BBR L;  3PO3 L;  1TWC L;  3GTP L;  3HOU L;  4A3E L;  4A3B L;  1I3Q L;  1Y1W L;  2R93 L;  4BXX L; 
#chains in the Genus database with same CATH topology
 1R0G A;  3GTG L;  3HJW B;  2A69 D;  2O5J D;  4GS7 D;  3VPB E;  5MGN A;  1QCV A;  3GTL L;  1VZI A;  4BBS L;  5DM6 1;  5IYC L;  2PVE A;  4QIW P;  2V0E A;  4LHL A;  2JA8 L;  5AI3 A;  1BQ8 A;  1TWH L;  2NYD A;  1OWB A;  3LNL A;  4ZN1 B;  4A3L L;  1RDV A;  1S30 A;  2R7Z L;  1RYQ A;  3MQK B;  1IRN A;  4JAG A;  2K2D A;  5IYD L;  2CR8 A;  5IP7 L;  4A93 L;  1T9Q A;  3GTQ L;  2B5I D;  2KN9 A;  2XJQ A;  4XXB B;  1NXG A;  3S1N L;  3PZA A;  3PL5 A;  4V19 6;  1SMW A;  4JAD A;  1RDG A;  1YV1 A;  3H3V M;  1PFY A;  4A3I L;  2JA7 L;  1OWC A;  2PSM C;  2RFK B;  1LTL A;  1B71 A;  2VUM L;  4B8C D;  2APO B;  3J7Z 1;  3S2D L;  2Z3Q B;  1TWG L;  4AR5 A;  1R9T L;  5GAD c;  2JI1 A;  5EIN C;  1IU6 A;  1S2Z A;  5AN9 H;  4G6B A;  3PO3 L;  1TWC L;  4A3E L;  1RWD A;  2AQC A;  6RXN A;  2C6A A;  2QL0 A;  5DM7 1;  3WWN B;  5M3M L;  3B0A B;  4A3G L;  3KYX A;  3RZD L;  1CAA A;  1E8J A;  2XJU A;  3P8B A;  1B13 A;  1IU5 A;  4C3J L;  2M6P A;  2V3B B;  2HVY C;  1PFU A;  3PIP 1;  1PZX A;  1DX8 A;  2M4Y A;  1LKM A;  4WFN 1;  1FHM A;  1YUX A;  4POF A;  3MSU A;  2V0F A;  5M5X L;  1P7P A;  4C3H L;  2NVT L;  4A3J L;  1YK5 A;  5GAE c;  4TVM A;  4TPU A;  2AUS B;  4Y52 L;  3GTK L;  1B2O A;  4AI3 A;  8RXN A;  3I4N L;  4BY1 L;  2BE5 D;  4LHN A;  3S16 L;  3LWR B;  5MFP A;  1R0J A;  3M4O L;  1SMM A;  2AYJ A;  5IY0 A;  3IU3 I;  4UY8 1;  5MF6 A;  3H9C A;  4POG A;  2E2J L;  2XJT A;  1F4L A;  5C4X L;  2XJV A;  2E2I L;  1LKO A;  4AYB P;  3KYW A;  1RYT A;  3GTJ L;  4RXN A;  4ZN3 B;  4A3C L;  1NNQ A;  2PMZ P;  3LWP B;  1BE7 A;  2PYA A;  4AHX A;  1VCX A;  2H12 A;  3KYY A;  4AI0 A;  1I3Q L;  2ERS A;  4BXX L;  3LWV B;  4C3I L;  3KYV A;  3HOX L;  4A3D L;  1NXE A;  5AI2 A;  1VZG A;  2C6B A;  4AR4 A;  2NVX L;  3K7A L;  1I6H L;  3HOY L;  4X6A L;  3S1Q L;  2LCQ A;  7RXN A;  1JYB A;  2Y0S P;  1PFV A;  4AHY A;  3RYG A;  3GTM L;  3S17 L;  3KYU A;  1S24 A;  1PFW A;  3JR7 A;  4YWM A;  2JA6 L;  2JA5 L;  1YUZ A;  5IYB L;  2MS3 A;  5M5Y L;  3QVD A;  1SFO L;  5GAG c;  2L0Z A;  3H99 A;  1R0H A;  4C2M 1;  1ODH A;  3SS2 A;  5EIO C;  5M5W L;  3PKI A;  1T9O A;  2A68 D;  3PIO 1;  3M3Y L;  2A6H D;  2RDV A;  1WJV A;  3S1R L;  1R0I A;  2M6O A;  5C4J L;  3HOZ L;  2CKA A;  2XJP A;  4AHW A;  3HOV L;  2KKD A;  5JVG 1;  3WWL A;  5RXN A;  2J9U B;  5MFZ A;  3HAX C;  4AI1 A;  5C44 L;  5GAH c;  3HJY B;  3S14 L;  4Y7N L;  1WCM L;  1Y1V L;  2GMG A;  5C3E L;  1FHH A;  3NFP I;  3P2A A;  5IP9 L;  1IRO A;  2DSX A;  3GTP L;  3HOU L;  1R0F A;  1BRF A;  3FDJ A;  2R93 L;  3PKJ A;  3RZT A;  2Z3R B;  1YK4 A;  4JAE A;  4AI2 A;  3RZO L;  2VL6 A;  3S1M L;  2B63 L;  1SMU A;  2ZIX A;  2XJR A;  2R92 L;  3ZG6 A;  1C09 A;  1LKP A;  1H7V A;  1VZH A;  4A3K L;  2EY4 E;  2XJS A;  2JI3 A;  3FKI L;  2PPT A;  5M3F L;  3PWF A;  5FLM L;  1BQ9 A;  3H97 A;  3LWO B;  1ZRP A;  4E6Y A;  1K83 L;  1TWF L;  1Z92 B;  3J7Y 1;  2A6E D;  3RZ6 A;  1I50 L;  4BY7 L;  1TWA L;  3HKZ P;  2JI2 A;  1IW7 D;  3I4M L;  2M4V A;  1QYB A;  1QQT A;  3H0G L;  1B2J A;  3GTO L;  3HOW L;  2WB1 P;  3S15 L;  2ERJ A;  2NVY L;  3K35 A;  3B08 B;  3MPS A;  5JVH 1;  2NVQ L;  5FJ8 L;  3LPE B;  4AHZ A;  3LWQ B;  1RB9 A;  4A3F L;  2CKC A;  3QQC E;  5H1S c;  1BFY A;  2YU9 L;  2WAQ P;  2E2H L;  1DVB A;  2PVX A;  3A44 A;  5MLC 3;  4A3M L;  4XGH A;  3PO2 L;  3CQZ L;  3S2H L;  2HR5 A;  4AR3 A;  5K2M E;  4BBR L;  4AR6 A;  4JAF A;  3H9B A;  1T9P A;  4A3B L;  4ME3 A;  4K9F A;  1CAD A;  4YWL A;  4U67 1;  1Y1W L; 
#chains in the Genus database with same CATH homology
 4C3I L;  5M3M L;  3RZO L;  3S1M L;  3HOX L;  4A3G L;  4A3D L;  3GTG L;  2B63 L;  3RZD L;  2NVX L;  3K7A L;  2R92 L;  1I6H L;  3HOY L;  4C3J L;  3S1Q L;  4X6A L;  4A3K L;  2Y0S P;  3FKI L;  3GTL L;  4BBS L;  5M3F L;  3GTM L;  5IYC L;  4QIW P;  3S17 L;  5FLM L;  2JA8 L;  1TWH L;  4A3L L;  5M5X L;  2JA6 L;  4C3H L;  2NVT L;  1K83 L;  2JA5 L;  4A3J L;  5IYB L;  4Y52 L;  1TWF L;  3GTK L;  2R7Z L;  5M5Y L;  1SFO L;  1I50 L;  4BY7 L;  1TWA L;  4C2M 1;  3HKZ P;  5IYD L;  5M5W L;  3I4N L;  4BY1 L;  3I4M L;  5IP7 L;  3S16 L;  3H0G L;  4A93 L;  3GTO L;  3HOW L;  3M3Y L;  2WB1 P;  3GTQ L;  3S15 L;  3M4O L;  2NVY L;  3S1N L;  3S1R L;  5C4J L;  2NVQ L;  3HOZ L;  5FJ8 L;  2E2J L;  3H3V M;  4A3F L;  4A3I L;  2JA7 L;  3HOV L;  2YU9 L;  5C4X L;  2WAQ P;  2E2I L;  2E2H L;  4A3M L;  4AYB P;  3PO2 L;  5C44 L;  3S14 L;  3CQZ L;  3GTJ L;  4Y7N L;  2VUM L;  1WCM L;  3S2D L;  3S2H L;  1Y1V L;  4A3C L;  5C3E L;  1TWG L;  2PMZ P;  1R9T L;  5IP9 L;  4BBR L;  3PO3 L;  1TWC L;  3GTP L;  3HOU L;  4A3E L;  4A3B L;  1I3Q L;  1Y1W L;  2R93 L;  4BXX L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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