4A3EL

Rna polymerase ii initial transcribing complex with a 5nt dna-rna hybrid and soaked with ampcpp
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4a3eL00
3HOUL 3HKZP 3S2HL 5IP7L 4A3LL 1I50L 4C3HL 2E2IL 4A3IL 3HOZL 3S17L 2WB1P 1Y1WL 2JA8L 2R92L 3HOXL 4BBSL 1I3QL 3S1NL 1K83L 4C3JL 2R93L 5M5YL 5FJ8L 3GTLL 1WCML 5IP9L 4A3EL 3PO3L 2E2HL 3S15L 3K7AL 3GTQL 5IYDL 2B63L 5FLML 3PO2L 2R7ZL 4A3GL 4C2M1 3H3VM 3M3YL 2PMZP 3I4ML 3GTML 4A3JL 3S1ML 4BBRL 1I6HL 4Y52L 2NVQL 3S1RL 4QIWP 5C44L 4A3BL 3GTJL 4BY1L 4AYBP 5M3FL 3GTGL 4A3KL 2NVTL 3FKIL 3I4NL 2WAQP 3RZDL 3RZOL 3M4OL 3HOWL 3HOVL 5M5WL 3S2DL 1TWAL 5C4XL 2NVYL 3GTKL 2YU9L 5IYBL 5M5XL 2Y0SP 3S14L 3GTPL 4A3CL 3S1QL 1TWFL 2JA5L 3GTOL 1R9TL 5M3ML 2VUML 4A3DL 5IYCL 1TWCL 3HOYL 5C4JL 3H0GL 2E2JL 3CQZL 1TWHL 1Y1VL 4C3IL 4Y7NL 4A3FL 4BY7L 1SFOL 2JA7L 2JA6L 5C3EL 3S16L 4A93L 2NVXL 1TWGL 4BXXL 4X6AL 4A3ML
chains in the Genus database with same CATH superfamily
3HOUL 3HKZP 5IP7L 1S2ZA 2APOB 2XJTA 3B0AB 4AI0A 2M6PA 4A3IL 3PWFA 1PFYA 2KN9A 1Y1WL 1S30A 1RDGA 1BQ8A 2H12A 4POGA 1CADA 1JYBA 5IP9L 4A3EL 2E2HL 3GTQL 1BRFA 3MPSA 5IYDL 3K35A 3B08B 5DM71 4AHWA 1IRNA 2A6HD 5GAGc 3GTML 1WJVA 1QQTA 2JI3A 2Z3QB 4Y52L 2NVQL 4TVMA 4QIWP 3RYGA 5C44L 2PVXA 2XJPA 1R0FA 3QVDA 1RYQA 2A69D 4POFA 1H7VA 1DVBA 4JAFA 5GAHc 2ERSA 3RZDL 3LNLA 4GS7D 4AHYA 2HR5A 2A6ED 2Z3RB 1YV1A 4AHXA 2NVYL 2JI2A 4WFN1 1YUZA 5AI3A 2QL0A 1PFVA 2XJUA 4RXNA 1IW7D 4U671 4A3CL 1IROA 1TWFL 3LWVB 1SMWA 1R0JA 5M3ML 3LWPB 2J9UB 5MFZA 2AUSB 1Y1VL 2M4VA 1SFOL 2NYDA 2JA6L 4JAEA 2BE5D 5DM61 2B5ID 1FHHA 3S16L 1VZHA 4A93L 2NVXL 1TWGL 3PKJA 2AYJA 4X6AL 1ODHA 1R0GA 5EINC 3J7Z1 2PSMC 4ZN1B 3S17L 2XJVA 1RYTA 2WB1P 5H1Sc 2VL6A 2R92L 4BBSL 1I3QL 2HVYC 5GAEc 3J7Y1 1YK4A 2ZIXA 5FJ8L 1B13A 1YUXA 1QCVA 1WCML 1R0IA 3PO3L 1VZGA 5JVG1 3H9CA 1RDVA 2C6BA 2MS3A 3PO2L 2R7ZL 4A3GL 1IU6A 3M3YL 2PMZP 4K9FA 4AR4A 3H99A 3LWOB 1I6HL 2CKAA 3SS2A 4A3BL 4JAGA 5M3FL 3I4NL 1B2JA 2DSXA 3PKIA 4LHLA 3HOVL 3MSUA 3P2AA 2JI1A 5M5XL 1R0HA 1RB9A 1OWBA 4AI2A 3NFPI 4YWMA 2ERJA 3GTOL 2C6AA 1NNQA 6RXNA 1VZIA 5IYCL 3HOYL 3FDJA 3H0GL 1BE7A 1TWHL 3H97A 3VPBE 3LWQB 3ZG6A 1YK5A 3P8BA 3KYYA 4AI3A 1NXGA 3KYWA 1QYBA 4ZN3B 4B8CD 4UY81 1I50L 4C3HL 1PFUA 1F4LA 4AR5A 1LTLA 4YWLA 2M4YA 5RXNA 4TPUA 3S1NL 1K83L 1PZXA 4ME3A 3LPEB 3WWNB 5M5YL 3PL5A 2V0FA 5MLC3 3S15L 3K7AL 1PFWA 1RWDA 3H3VM 5MF6A 2A68D 3PZAA 1ZRPA 1Z92B 5MFPA 3I4ML 4A3JL 3S1RL 4BY1L 2EY4E 1IU5A 3GTGL 2NVTL 3FKIL 2WAQP 2V0EA 3RZOL 3M4OL 3A44A 5MGNA 3S2DL 1TWAL 5C4XL 3JR7A 3KYVA 2LCQA 5IYBL 2V3BB 5JVH1 2AQCA 3IU3I 3S1QL 2JA5L 2K2DA 2CR8A 5C4JL 2E2JL 3CQZL 4BY7L 4A3FL 2XJRA 1VCXA 4XGHA 3LWRB 1SMMA 4BXXL 4A3ML 2PPTA 4LHNA 8RXNA 3S2HL 1LKPA 4A3LL 3PIO1 2E2IL 3RZ6A 3HOZL 1OWCA 4AR3A 2PYAA 2O5JD 5K2ME 2JA8L 3HOXL 3MQKB 2RFKB 4C3JL 2R93L 1T9OA 3GTLL 3HJYB 1B2OA 3QQCE 3RZTA 2RDVA 4V196 2B63L 1BFYA 5FLML 4C2M1 4AR6A 7RXNA 1T9QA 3S1ML 2GMGA 1DX8A 1LKMA 4BBRL 1P7PA 4G6BA 3GTJL 1FHMA 3HAXC 3PIP1 5AN9H 4AYBP 1S24A 2L0ZA 4A3KL 2PVEA 1E8JA 1LKOA 2M6OA 3WWLA 3HJWB 2KKDA 1SMUA 3HOWL 5M5WL 1T9PA 2XJSA 4XXBB 3GTKL 1NXEA 2YU9L 5EIOC 5IY0A 1CAAA 2Y0SP 3S14L 3GTPL 3H9BA 4AI1A 4E6YA 1B71A 1R9TL 3KYXA 2VUML 4A3DL 1C09A 4AHZA 1TWCL 2CKCA 4Y7NL 4C3IL 2JA7L 3KYUA 5GADc 2XJQA 1BQ9A 5C3EL 5AI2A 4JADA
chains in the Genus database with same CATH topology
3HOUL 3HKZP 3S2HL 5IP7L 4A3LL 1I50L 4C3HL 2E2IL 4A3IL 3HOZL 3S17L 2WB1P 1Y1WL 2JA8L 2R92L 3HOXL 4BBSL 1I3QL 3S1NL 1K83L 4C3JL 2R93L 5M5YL 5FJ8L 3GTLL 1WCML 5IP9L 4A3EL 3PO3L 2E2HL 3S15L 3K7AL 3GTQL 5IYDL 2B63L 5FLML 3PO2L 2R7ZL 4A3GL 4C2M1 3H3VM 3M3YL 2PMZP 3I4ML 3GTML 4A3JL 3S1ML 4BBRL 1I6HL 4Y52L 2NVQL 3S1RL 4QIWP 5C44L 4A3BL 3GTJL 4BY1L 4AYBP 5M3FL 3GTGL 4A3KL 2NVTL 3FKIL 3I4NL 2WAQP 3RZDL 3RZOL 3M4OL 3HOWL 3HOVL 5M5WL 3S2DL 1TWAL 5C4XL 2NVYL 3GTKL 2YU9L 5IYBL 5M5XL 2Y0SP 3S14L 3GTPL 4A3CL 3S1QL 1TWFL 2JA5L 3GTOL 1R9TL 5M3ML 2VUML 4A3DL 5IYCL 1TWCL 3HOYL 5C4JL 3H0GL 2E2JL 3CQZL 1TWHL 1Y1VL 4C3IL 4Y7NL 4A3FL 4BY7L 1SFOL 2JA7L 2JA6L 5C3EL 3S16L 4A93L 2NVXL 1TWGL 4BXXL 4X6AL 4A3ML
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HOU L;  3HKZ P;  3S2H L;  5IP7 L;  4A3L L;  1I50 L;  4C3H L;  2E2I L;  4A3I L;  3HOZ L;  3S17 L;  2WB1 P;  1Y1W L;  2JA8 L;  2R92 L;  3HOX L;  4BBS L;  1I3Q L;  3S1N L;  1K83 L;  4C3J L;  2R93 L;  5M5Y L;  5FJ8 L;  3GTL L;  1WCM L;  5IP9 L;  4A3E L;  3PO3 L;  2E2H L;  3S15 L;  3K7A L;  3GTQ L;  5IYD L;  2B63 L;  5FLM L;  3PO2 L;  2R7Z L;  4A3G L;  4C2M 1;  3H3V M;  3M3Y L;  2PMZ P;  3I4M L;  3GTM L;  4A3J L;  3S1M L;  4BBR L;  1I6H L;  4Y52 L;  2NVQ L;  3S1R L;  4QIW P;  5C44 L;  4A3B L;  3GTJ L;  4BY1 L;  4AYB P;  5M3F L;  3GTG L;  4A3K L;  2NVT L;  3FKI L;  3I4N L;  2WAQ P;  3RZD L;  3RZO L;  3M4O L;  3HOW L;  3HOV L;  5M5W L;  3S2D L;  1TWA L;  5C4X L;  2NVY L;  3GTK L;  2YU9 L;  5IYB L;  5M5X L;  2Y0S P;  3S14 L;  3GTP L;  4A3C L;  3S1Q L;  1TWF L;  2JA5 L;  3GTO L;  1R9T L;  5M3M L;  2VUM L;  4A3D L;  5IYC L;  1TWC L;  3HOY L;  5C4J L;  3H0G L;  2E2J L;  3CQZ L;  1TWH L;  1Y1V L;  4C3I L;  4Y7N L;  4A3F L;  4BY7 L;  1SFO L;  2JA7 L;  2JA6 L;  5C3E L;  3S16 L;  4A93 L;  2NVX L;  1TWG L;  4BXX L;  4X6A L;  4A3M L; 
#chains in the Genus database with same CATH topology
 3HOU L;  3HKZ P;  5IP7 L;  1S2Z A;  2APO B;  2XJT A;  3B0A B;  4AI0 A;  2M6P A;  4A3I L;  3PWF A;  1PFY A;  2KN9 A;  1Y1W L;  1S30 A;  1RDG A;  1BQ8 A;  2H12 A;  4POG A;  1CAD A;  1JYB A;  5IP9 L;  4A3E L;  2E2H L;  3GTQ L;  1BRF A;  3MPS A;  5IYD L;  3K35 A;  3B08 B;  5DM7 1;  4AHW A;  1IRN A;  2A6H D;  5GAG c;  3GTM L;  1WJV A;  1QQT A;  2JI3 A;  2Z3Q B;  4Y52 L;  2NVQ L;  4TVM A;  4QIW P;  3RYG A;  5C44 L;  2PVX A;  2XJP A;  1R0F A;  3QVD A;  1RYQ A;  2A69 D;  4POF A;  1H7V A;  1DVB A;  4JAF A;  5GAH c;  2ERS A;  3RZD L;  3LNL A;  4GS7 D;  4AHY A;  2HR5 A;  2A6E D;  2Z3R B;  1YV1 A;  4AHX A;  2NVY L;  2JI2 A;  4WFN 1;  1YUZ A;  5AI3 A;  2QL0 A;  1PFV A;  2XJU A;  4RXN A;  1IW7 D;  4U67 1;  4A3C L;  1IRO A;  1TWF L;  3LWV B;  1SMW A;  1R0J A;  5M3M L;  3LWP B;  2J9U B;  5MFZ A;  2AUS B;  1Y1V L;  2M4V A;  1SFO L;  2NYD A;  2JA6 L;  4JAE A;  2BE5 D;  5DM6 1;  2B5I D;  1FHH A;  3S16 L;  1VZH A;  4A93 L;  2NVX L;  1TWG L;  3PKJ A;  2AYJ A;  4X6A L;  1ODH A;  1R0G A;  5EIN C;  3J7Z 1;  2PSM C;  4ZN1 B;  3S17 L;  2XJV A;  1RYT A;  2WB1 P;  5H1S c;  2VL6 A;  2R92 L;  4BBS L;  1I3Q L;  2HVY C;  5GAE c;  3J7Y 1;  1YK4 A;  2ZIX A;  5FJ8 L;  1B13 A;  1YUX A;  1QCV A;  1WCM L;  1R0I A;  3PO3 L;  1VZG A;  5JVG 1;  3H9C A;  1RDV A;  2C6B A;  2MS3 A;  3PO2 L;  2R7Z L;  4A3G L;  1IU6 A;  3M3Y L;  2PMZ P;  4K9F A;  4AR4 A;  3H99 A;  3LWO B;  1I6H L;  2CKA A;  3SS2 A;  4A3B L;  4JAG A;  5M3F L;  3I4N L;  1B2J A;  2DSX A;  3PKI A;  4LHL A;  3HOV L;  3MSU A;  3P2A A;  2JI1 A;  5M5X L;  1R0H A;  1RB9 A;  1OWB A;  4AI2 A;  3NFP I;  4YWM A;  2ERJ A;  3GTO L;  2C6A A;  1NNQ A;  6RXN A;  1VZI A;  5IYC L;  3HOY L;  3FDJ A;  3H0G L;  1BE7 A;  1TWH L;  3H97 A;  3VPB E;  3LWQ B;  3ZG6 A;  1YK5 A;  3P8B A;  3KYY A;  4AI3 A;  1NXG A;  3KYW A;  1QYB A;  4ZN3 B;  4B8C D;  4UY8 1;  1I50 L;  4C3H L;  1PFU A;  1F4L A;  4AR5 A;  1LTL A;  4YWL A;  2M4Y A;  5RXN A;  4TPU A;  3S1N L;  1K83 L;  1PZX A;  4ME3 A;  3LPE B;  3WWN B;  5M5Y L;  3PL5 A;  2V0F A;  5MLC 3;  3S15 L;  3K7A L;  1PFW A;  1RWD A;  3H3V M;  5MF6 A;  2A68 D;  3PZA A;  1ZRP A;  1Z92 B;  5MFP A;  3I4M L;  4A3J L;  3S1R L;  4BY1 L;  2EY4 E;  1IU5 A;  3GTG L;  2NVT L;  3FKI L;  2WAQ P;  2V0E A;  3RZO L;  3M4O L;  3A44 A;  5MGN A;  3S2D L;  1TWA L;  5C4X L;  3JR7 A;  3KYV A;  2LCQ A;  5IYB L;  2V3B B;  5JVH 1;  2AQC A;  3IU3 I;  3S1Q L;  2JA5 L;  2K2D A;  2CR8 A;  5C4J L;  2E2J L;  3CQZ L;  4BY7 L;  4A3F L;  2XJR A;  1VCX A;  4XGH A;  3LWR B;  1SMM A;  4BXX L;  4A3M L;  2PPT A;  4LHN A;  8RXN A;  3S2H L;  1LKP A;  4A3L L;  3PIO 1;  2E2I L;  3RZ6 A;  3HOZ L;  1OWC A;  4AR3 A;  2PYA A;  2O5J D;  5K2M E;  2JA8 L;  3HOX L;  3MQK B;  2RFK B;  4C3J L;  2R93 L;  1T9O A;  3GTL L;  3HJY B;  1B2O A;  3QQC E;  3RZT A;  2RDV A;  4V19 6;  2B63 L;  1BFY A;  5FLM L;  4C2M 1;  4AR6 A;  7RXN A;  1T9Q A;  3S1M L;  2GMG A;  1DX8 A;  1LKM A;  4BBR L;  1P7P A;  4G6B A;  3GTJ L;  1FHM A;  3HAX C;  3PIP 1;  5AN9 H;  4AYB P;  1S24 A;  2L0Z A;  4A3K L;  2PVE A;  1E8J A;  1LKO A;  2M6O A;  3WWL A;  3HJW B;  2KKD A;  1SMU A;  3HOW L;  5M5W L;  1T9P A;  2XJS A;  4XXB B;  3GTK L;  1NXE A;  2YU9 L;  5EIO C;  5IY0 A;  1CAA A;  2Y0S P;  3S14 L;  3GTP L;  3H9B A;  4AI1 A;  4E6Y A;  1B71 A;  1R9T L;  3KYX A;  2VUM L;  4A3D L;  1C09 A;  4AHZ A;  1TWC L;  2CKC A;  4Y7N L;  4C3I L;  2JA7 L;  3KYU A;  5GAD c;  2XJQ A;  1BQ9 A;  5C3E L;  5AI2 A;  4JAD A; 
#chains in the Genus database with same CATH homology
 3HOU L;  3HKZ P;  3S2H L;  5IP7 L;  4A3L L;  1I50 L;  4C3H L;  2E2I L;  4A3I L;  3HOZ L;  3S17 L;  2WB1 P;  1Y1W L;  2JA8 L;  2R92 L;  3HOX L;  4BBS L;  1I3Q L;  3S1N L;  1K83 L;  4C3J L;  2R93 L;  5M5Y L;  5FJ8 L;  3GTL L;  1WCM L;  5IP9 L;  4A3E L;  3PO3 L;  2E2H L;  3S15 L;  3K7A L;  3GTQ L;  5IYD L;  2B63 L;  5FLM L;  3PO2 L;  2R7Z L;  4A3G L;  4C2M 1;  3H3V M;  3M3Y L;  2PMZ P;  3I4M L;  3GTM L;  4A3J L;  3S1M L;  4BBR L;  1I6H L;  4Y52 L;  2NVQ L;  3S1R L;  4QIW P;  5C44 L;  4A3B L;  3GTJ L;  4BY1 L;  4AYB P;  5M3F L;  3GTG L;  4A3K L;  2NVT L;  3FKI L;  3I4N L;  2WAQ P;  3RZD L;  3RZO L;  3M4O L;  3HOW L;  3HOV L;  5M5W L;  3S2D L;  1TWA L;  5C4X L;  2NVY L;  3GTK L;  2YU9 L;  5IYB L;  5M5X L;  2Y0S P;  3S14 L;  3GTP L;  4A3C L;  3S1Q L;  1TWF L;  2JA5 L;  3GTO L;  1R9T L;  5M3M L;  2VUM L;  4A3D L;  5IYC L;  1TWC L;  3HOY L;  5C4J L;  3H0G L;  2E2J L;  3CQZ L;  1TWH L;  1Y1V L;  4C3I L;  4Y7N L;  4A3F L;  4BY7 L;  1SFO L;  2JA7 L;  2JA6 L;  5C3E L;  3S16 L;  4A93 L;  2NVX L;  1TWG L;  4BXX L;  4X6A L;  4A3M L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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