4A3FL

Rna polymerase ii initial transcribing complex with a 6nt dna-rna hybrid and soaked with ampcpp
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4a3fL00
3HOZL 5M5XL 5M5YL 4C3JL 1Y1WL 2VUML 3S1NL 4C3HL 2R92L 2JA8L 4A3ML 3M3YL 4A3LL 3HKZP 3K7AL 3GTLL 4A3BL 4A93L 3GTGL 3GTKL 2WB1P 5M3ML 2NVQL 4Y52L 4A3EL 3HOXL 3GTML 2JA6L 1TWAL 4A3JL 3HOUL 3HOYL 1TWFL 4BBRL 3H3VM 4AYBP 3I4NL 2NVTL 4A3DL 4A3CL 5M3FL 2JA7L 2PMZP 3S15L 2R7ZL 5IP9L 3I4ML 1I6HL 3S1QL 2NVXL 2R93L 3HOWL 4BXXL 4A3IL 5IYBL 2E2IL 1TWGL 1I3QL 4QIWP 3GTPL 3PO2L 2Y0SP 5C4XL 3GTOL 4X6AL 3RZDL 1TWHL 2YU9L 3PO3L 3H0GL 5C3EL 1K83L 3CQZL 2WAQP 4A3GL 3S16L 2NVYL 2E2JL 5IYDL 4A3FL 3GTQL 3RZOL 3M4OL 5IYCL 3S1RL 4C3IL 3S2HL 4Y7NL 1Y1VL 5M5WL 2B63L 4BBSL 4C2M1 1I50L 5C44L 3HOVL 1SFOL 2JA5L 4A3KL 5FLML 4BY1L 3S1ML 2E2HL 5IP7L 3S2DL 3FKIL 5FJ8L 4BY7L 3S14L 5C4JL 1TWCL 3S17L 3GTJL 1R9TL 1WCML
chains in the Genus database with same CATH superfamily
2V0FA 5M5YL 2VUML 5AI2A 2R92L 1P7PA 1IW7D 3KYYA 3GTLL 2ERJA 2MS3A 2A69D 2Z3QB 5MF6A 1F4LA 3MSUA 1YUXA 2B5ID 5GAEc 4A3EL 1PFWA 3PIP1 3GTML 2JA6L 2ZIXA 4AI1A 3HOYL 2C6BA 1R9TL 4AHYA 1R0IA 1TWFL 4JAEA 1FHMA 5M3FL 3LWPB 3S15L 1PFYA 3J7Z1 4WFN1 1YK4A 1VZHA 2XJPA 5GADc 3HOWL 1S24A 2XJSA 1OWCA 3RZ6A 2E2IL 2BE5D 5EIOC 2Y0SP 4ZN3B 2CKAA 1JYBA 4XGHA 1YV1A 2E2JL 5IYDL 1CAAA 4LHNA 1VZGA 2PVXA 3GTQL 4JAGA 1IRNA 5MFPA 4ME3A 5IYCL 4POFA 3S1RL 1Y1VL 1B2OA 1BE7A 4C2M1 4YWMA 4AHXA 1DVBA 3KYWA 1PFVA 4XXBB 1C09A 3B0AB 3QVDA 4AHZA 4AR6A 3PKIA 2EY4E 1BRFA 3QQCE 2AQCA 3GTJL 3B08B 1T9PA 2DSXA 2KN9A 4C3HL 5DM71 3NFPI 2XJUA 4A3ML 2JA8L 3MQKB 1IU5A 2XJTA 1R0FA 4A93L 2HR5A 2HVYC 1ZRPA 2H12A 3IU3I 3GTKL 5M3ML 3RYGA 2VL6A 1BQ8A 2JI1A 5IY0A 1RWDA 3VPBE 2GMGA 1QYBA 2AYJA 1BQ9A 3I4NL 3H9CA 3LWOB 2JA7L 1T9QA 4GS7D 1SMWA 1T9OA 2R93L 2M6PA 2PVEA 1YUZA 5GAHc 3PWFA 2L0ZA 1FHHA 2KKDA 4LHLA 5AI3A 3WWNB 3GTOL 2YU9L 5C3EL 3CQZL 5GAGc 4A3GL 2NVYL 3P2AA 4A3FL 5AN9H 4V196 1RDGA 1LKOA 1E8JA 2APOB 1B71A 2Z3RB 4C3IL 3S2HL 1LKMA 3HJYB 2V3BB 1B2JA 2XJRA 5H1Sc 1LKPA 5C44L 2C6AA 3PZAA 3ZG6A 2JA5L 5FLML 2E2HL 4TPUA 3HAXC 1WJVA 3S2DL 3PIO1 4AI3A 4BY7L 4B8CD 3H9BA 1Z92B 2A6HD 1WCML 2AUSB 3HOZL 2K2DA 2PPTA 3MPSA 3SS2A 1Y1WL 4C3JL 2QL0A 2XJVA 2NYDA 1BFYA 4ZN1B 3M3YL 2LCQA 4A3LL 4A3BL 4G6BA 4TVMA 3GTGL 4AR3A 4RXNA 2WB1P 1CADA 2NVQL 3HOXL 1SMUA 1OWBA 1TWAL 4A3JL 3HOUL 1SMMA 1H7VA 4AYBP 2CKCA 4YWLA 1NXGA 1VCXA 3I4ML 3S1QL 2NVXL 4BXXL 5IYBL 1TWGL 1PZXA 1I3QL 3GTPL 1R0HA 5C4XL 4X6AL 1IROA 2RDVA 3RZDL 1TWHL 1QQTA 3H0GL 1K83L 6RXNA 1QCVA 3S16L 3HJWB 2A68D 3LPEB 3KYVA 3K35A 1S30A 3RZOL 2PYAA 5MGNA 3LNLA 4JAFA 4AI0A 1S2ZA 2RFKB 1RYTA 1YK5A 3PL5A 1RYQA 1SFOL 4UY81 5JVG1 3FKIL 5FJ8L 5C4JL 1TWCL 1VZIA 3KYXA 4AR5A 3RZTA 4U671 5M5XL 3LWRB 3S1NL 3FDJA 3KYUA 3HKZP 2M6OA 3K7AL 3J7Y1 2ERSA 4AR4A 1DX8A 1PFUA 4AI2A 4Y52L 5RXNA 3JR7A 3A44A 4BBRL 3H3VM 1LTLA 2PSMC 5MFZA 2NVTL 4A3CL 4A3DL 2PMZP 2JI2A 1B13A 2M4YA 2R7ZL 5IP9L 7RXNA 5JVH1 3H99A 2CR8A 2M4VA 1I6HL 1RB9A 5K2ME 3PKJA 4A3IL 1R0GA 2J9UB 2A6ED 1IU6A 4QIWP 3PO2L 2O5JD 3P8BA 2XJQA 3PO3L 5DM61 4K9FA 3H97A 4E6YA 5EINC 2WAQP 1NXEA 4POGA 5MLC3 8RXNA 1ODHA 3M4OL 2V0EA 3LWQB 4Y7NL 4BBSL 5M5WL 2B63L 1I50L 3HOVL 4A3KL 2JI3A 4BY1L 3S1ML 1NNQA 5IP7L 1R0JA 3S14L 4AHWA 3WWLA 3S17L 3LWVB 1RDVA 4JADA
chains in the Genus database with same CATH topology
3HOZL 5M5XL 5M5YL 4C3JL 1Y1WL 2VUML 3S1NL 4C3HL 2R92L 2JA8L 4A3ML 3M3YL 4A3LL 3HKZP 3K7AL 3GTLL 4A3BL 4A93L 3GTGL 3GTKL 2WB1P 5M3ML 2NVQL 4Y52L 4A3EL 3HOXL 3GTML 2JA6L 1TWAL 4A3JL 3HOUL 3HOYL 1TWFL 4BBRL 3H3VM 4AYBP 3I4NL 2NVTL 4A3DL 4A3CL 5M3FL 2JA7L 2PMZP 3S15L 2R7ZL 5IP9L 3I4ML 1I6HL 3S1QL 2NVXL 2R93L 3HOWL 4BXXL 4A3IL 5IYBL 2E2IL 1TWGL 1I3QL 4QIWP 3GTPL 3PO2L 2Y0SP 5C4XL 3GTOL 4X6AL 3RZDL 1TWHL 2YU9L 3PO3L 3H0GL 5C3EL 1K83L 3CQZL 2WAQP 4A3GL 3S16L 2NVYL 2E2JL 5IYDL 4A3FL 3GTQL 3RZOL 3M4OL 5IYCL 3S1RL 4C3IL 3S2HL 4Y7NL 1Y1VL 5M5WL 2B63L 4BBSL 4C2M1 1I50L 5C44L 3HOVL 1SFOL 2JA5L 4A3KL 5FLML 4BY1L 3S1ML 2E2HL 5IP7L 3S2DL 3FKIL 5FJ8L 4BY7L 3S14L 5C4JL 1TWCL 3S17L 3GTJL 1R9TL 1WCML
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HOZ L;  5M5X L;  5M5Y L;  4C3J L;  1Y1W L;  2VUM L;  3S1N L;  4C3H L;  2R92 L;  2JA8 L;  4A3M L;  3M3Y L;  4A3L L;  3HKZ P;  3K7A L;  3GTL L;  4A3B L;  4A93 L;  3GTG L;  3GTK L;  2WB1 P;  5M3M L;  2NVQ L;  4Y52 L;  4A3E L;  3HOX L;  3GTM L;  2JA6 L;  1TWA L;  4A3J L;  3HOU L;  3HOY L;  1TWF L;  4BBR L;  3H3V M;  4AYB P;  3I4N L;  2NVT L;  4A3D L;  4A3C L;  5M3F L;  2JA7 L;  2PMZ P;  3S15 L;  2R7Z L;  5IP9 L;  3I4M L;  1I6H L;  3S1Q L;  2NVX L;  2R93 L;  3HOW L;  4BXX L;  4A3I L;  5IYB L;  2E2I L;  1TWG L;  1I3Q L;  4QIW P;  3GTP L;  3PO2 L;  2Y0S P;  5C4X L;  3GTO L;  4X6A L;  3RZD L;  1TWH L;  2YU9 L;  3PO3 L;  3H0G L;  5C3E L;  1K83 L;  3CQZ L;  2WAQ P;  4A3G L;  3S16 L;  2NVY L;  2E2J L;  5IYD L;  4A3F L;  3GTQ L;  3RZO L;  3M4O L;  5IYC L;  3S1R L;  4C3I L;  3S2H L;  4Y7N L;  1Y1V L;  5M5W L;  2B63 L;  4BBS L;  4C2M 1;  1I50 L;  5C44 L;  3HOV L;  1SFO L;  2JA5 L;  4A3K L;  5FLM L;  4BY1 L;  3S1M L;  2E2H L;  5IP7 L;  3S2D L;  3FKI L;  5FJ8 L;  4BY7 L;  3S14 L;  5C4J L;  1TWC L;  3S17 L;  3GTJ L;  1R9T L;  1WCM L; 
#chains in the Genus database with same CATH topology
 2V0F A;  5M5Y L;  2VUM L;  5AI2 A;  2R92 L;  1P7P A;  1IW7 D;  3KYY A;  3GTL L;  2ERJ A;  2MS3 A;  2A69 D;  2Z3Q B;  5MF6 A;  1F4L A;  3MSU A;  1YUX A;  2B5I D;  5GAE c;  4A3E L;  1PFW A;  3PIP 1;  3GTM L;  2JA6 L;  2ZIX A;  4AI1 A;  3HOY L;  2C6B A;  1R9T L;  4AHY A;  1R0I A;  1TWF L;  4JAE A;  1FHM A;  5M3F L;  3LWP B;  3S15 L;  1PFY A;  3J7Z 1;  4WFN 1;  1YK4 A;  1VZH A;  2XJP A;  5GAD c;  3HOW L;  1S24 A;  2XJS A;  1OWC A;  3RZ6 A;  2E2I L;  2BE5 D;  5EIO C;  2Y0S P;  4ZN3 B;  2CKA A;  1JYB A;  4XGH A;  1YV1 A;  2E2J L;  5IYD L;  1CAA A;  4LHN A;  1VZG A;  2PVX A;  3GTQ L;  4JAG A;  1IRN A;  5MFP A;  4ME3 A;  5IYC L;  4POF A;  3S1R L;  1Y1V L;  1B2O A;  1BE7 A;  4C2M 1;  4YWM A;  4AHX A;  1DVB A;  3KYW A;  1PFV A;  4XXB B;  1C09 A;  3B0A B;  3QVD A;  4AHZ A;  4AR6 A;  3PKI A;  2EY4 E;  1BRF A;  3QQC E;  2AQC A;  3GTJ L;  3B08 B;  1T9P A;  2DSX A;  2KN9 A;  4C3H L;  5DM7 1;  3NFP I;  2XJU A;  4A3M L;  2JA8 L;  3MQK B;  1IU5 A;  2XJT A;  1R0F A;  4A93 L;  2HR5 A;  2HVY C;  1ZRP A;  2H12 A;  3IU3 I;  3GTK L;  5M3M L;  3RYG A;  2VL6 A;  1BQ8 A;  2JI1 A;  5IY0 A;  1RWD A;  3VPB E;  2GMG A;  1QYB A;  2AYJ A;  1BQ9 A;  3I4N L;  3H9C A;  3LWO B;  2JA7 L;  1T9Q A;  4GS7 D;  1SMW A;  1T9O A;  2R93 L;  2M6P A;  2PVE A;  1YUZ A;  5GAH c;  3PWF A;  2L0Z A;  1FHH A;  2KKD A;  4LHL A;  5AI3 A;  3WWN B;  3GTO L;  2YU9 L;  5C3E L;  3CQZ L;  5GAG c;  4A3G L;  2NVY L;  3P2A A;  4A3F L;  5AN9 H;  4V19 6;  1RDG A;  1LKO A;  1E8J A;  2APO B;  1B71 A;  2Z3R B;  4C3I L;  3S2H L;  1LKM A;  3HJY B;  2V3B B;  1B2J A;  2XJR A;  5H1S c;  1LKP A;  5C44 L;  2C6A A;  3PZA A;  3ZG6 A;  2JA5 L;  5FLM L;  2E2H L;  4TPU A;  3HAX C;  1WJV A;  3S2D L;  3PIO 1;  4AI3 A;  4BY7 L;  4B8C D;  3H9B A;  1Z92 B;  2A6H D;  1WCM L;  2AUS B;  3HOZ L;  2K2D A;  2PPT A;  3MPS A;  3SS2 A;  1Y1W L;  4C3J L;  2QL0 A;  2XJV A;  2NYD A;  1BFY A;  4ZN1 B;  3M3Y L;  2LCQ A;  4A3L L;  4A3B L;  4G6B A;  4TVM A;  3GTG L;  4AR3 A;  4RXN A;  2WB1 P;  1CAD A;  2NVQ L;  3HOX L;  1SMU A;  1OWB A;  1TWA L;  4A3J L;  3HOU L;  1SMM A;  1H7V A;  4AYB P;  2CKC A;  4YWL A;  1NXG A;  1VCX A;  3I4M L;  3S1Q L;  2NVX L;  4BXX L;  5IYB L;  1TWG L;  1PZX A;  1I3Q L;  3GTP L;  1R0H A;  5C4X L;  4X6A L;  1IRO A;  2RDV A;  3RZD L;  1TWH L;  1QQT A;  3H0G L;  1K83 L;  6RXN A;  1QCV A;  3S16 L;  3HJW B;  2A68 D;  3LPE B;  3KYV A;  3K35 A;  1S30 A;  3RZO L;  2PYA A;  5MGN A;  3LNL A;  4JAF A;  4AI0 A;  1S2Z A;  2RFK B;  1RYT A;  1YK5 A;  3PL5 A;  1RYQ A;  1SFO L;  4UY8 1;  5JVG 1;  3FKI L;  5FJ8 L;  5C4J L;  1TWC L;  1VZI A;  3KYX A;  4AR5 A;  3RZT A;  4U67 1;  5M5X L;  3LWR B;  3S1N L;  3FDJ A;  3KYU A;  3HKZ P;  2M6O A;  3K7A L;  3J7Y 1;  2ERS A;  4AR4 A;  1DX8 A;  1PFU A;  4AI2 A;  4Y52 L;  5RXN A;  3JR7 A;  3A44 A;  4BBR L;  3H3V M;  1LTL A;  2PSM C;  5MFZ A;  2NVT L;  4A3C L;  4A3D L;  2PMZ P;  2JI2 A;  1B13 A;  2M4Y A;  2R7Z L;  5IP9 L;  7RXN A;  5JVH 1;  3H99 A;  2CR8 A;  2M4V A;  1I6H L;  1RB9 A;  5K2M E;  3PKJ A;  4A3I L;  1R0G A;  2J9U B;  2A6E D;  1IU6 A;  4QIW P;  3PO2 L;  2O5J D;  3P8B A;  2XJQ A;  3PO3 L;  5DM6 1;  4K9F A;  3H97 A;  4E6Y A;  5EIN C;  2WAQ P;  1NXE A;  4POG A;  5MLC 3;  8RXN A;  1ODH A;  3M4O L;  2V0E A;  3LWQ B;  4Y7N L;  4BBS L;  5M5W L;  2B63 L;  1I50 L;  3HOV L;  4A3K L;  2JI3 A;  4BY1 L;  3S1M L;  1NNQ A;  5IP7 L;  1R0J A;  3S14 L;  4AHW A;  3WWL A;  3S17 L;  3LWV B;  1RDV A;  4JAD A; 
#chains in the Genus database with same CATH homology
 3HOZ L;  5M5X L;  5M5Y L;  4C3J L;  1Y1W L;  2VUM L;  3S1N L;  4C3H L;  2R92 L;  2JA8 L;  4A3M L;  3M3Y L;  4A3L L;  3HKZ P;  3K7A L;  3GTL L;  4A3B L;  4A93 L;  3GTG L;  3GTK L;  2WB1 P;  5M3M L;  2NVQ L;  4Y52 L;  4A3E L;  3HOX L;  3GTM L;  2JA6 L;  1TWA L;  4A3J L;  3HOU L;  3HOY L;  1TWF L;  4BBR L;  3H3V M;  4AYB P;  3I4N L;  2NVT L;  4A3D L;  4A3C L;  5M3F L;  2JA7 L;  2PMZ P;  3S15 L;  2R7Z L;  5IP9 L;  3I4M L;  1I6H L;  3S1Q L;  2NVX L;  2R93 L;  3HOW L;  4BXX L;  4A3I L;  5IYB L;  2E2I L;  1TWG L;  1I3Q L;  4QIW P;  3GTP L;  3PO2 L;  2Y0S P;  5C4X L;  3GTO L;  4X6A L;  3RZD L;  1TWH L;  2YU9 L;  3PO3 L;  3H0G L;  5C3E L;  1K83 L;  3CQZ L;  2WAQ P;  4A3G L;  3S16 L;  2NVY L;  2E2J L;  5IYD L;  4A3F L;  3GTQ L;  3RZO L;  3M4O L;  5IYC L;  3S1R L;  4C3I L;  3S2H L;  4Y7N L;  1Y1V L;  5M5W L;  2B63 L;  4BBS L;  4C2M 1;  1I50 L;  5C44 L;  3HOV L;  1SFO L;  2JA5 L;  4A3K L;  5FLM L;  4BY1 L;  3S1M L;  2E2H L;  5IP7 L;  3S2D L;  3FKI L;  5FJ8 L;  4BY7 L;  3S14 L;  5C4J L;  1TWC L;  3S17 L;  3GTJ L;  1R9T L;  1WCM L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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