4A3KL

Rna polymerase ii initial transcribing complex with a 7nt dna-rna hybrid
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Initial RNA Polymerase II Transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4a3kL00
4BY1L 2Y0SP 5C4JL 1K83L 4Y7NL 3S2HL 2YU9L 2B63L 3CQZL 1I50L 2NVTL 5IYDL 3HOUL 3GTKL 3HOXL 2R92L 3S1ML 5C3EL 3S16L 4A3IL 4C2M1 4QIWP 1TWAL 5FJ8L 3RZOL 3RZDL 1I6HL 3GTGL 5FLML 2JA5L 2NVXL 3I4ML 4BBRL 5M5WL 1SFOL 4BBSL 5IP9L 2WAQP 5C4XL 4Y52L 3GTOL 2R7ZL 5C44L 4A3ML 3FKIL 2WB1P 4A3KL 4C3HL 3GTJL 4C3JL 5IP7L 3K7AL 3S1NL 1TWHL 2PMZP 5IYCL 3M4OL 3S1QL 3I4NL 3M3YL 3GTML 3HOVL 3GTPL 3PO3L 1TWCL 3HOYL 3GTQL 1TWFL 3PO2L 4A3DL 2E2JL 3S15L 4A3EL 4A93L 3HOZL 4A3LL 3GTLL 5M5XL 2VUML 4A3JL 3H3VM 4A3CL 2JA8L 5M3ML 3S2DL 2R93L 1TWGL 3S1RL 2NVYL 5IYBL 4AYBP 5M3FL 1Y1WL 3HKZP 1R9TL 3HOWL 3H0GL 2E2HL 4C3IL 5M5YL 2JA6L 4X6AL 4A3FL 4BY7L 3S14L 1Y1VL 1I3QL 4A3GL 1WCML 4BXXL 2E2IL 2JA7L 2NVQL 4A3BL 3S17L
chains in the Genus database with same CATH superfamily
5C4JL 1K83L 4Y7NL 2YU9L 1YK5A 1S24A 2V0FA 1I50L 4K9FA 2DSXA 3HOXL 3S16L 4QIWP 1TWAL 2H12A 4RXNA 3LPEB 4AI2A 3GTGL 4JAFA 3KYWA 4BBRL 4BBSL 4Y52L 4AR5A 4A3ML 2WB1P 4AI3A 1LKOA 4C3HL 1P7PA 2XJUA 5MFPA 3GTJL 3PKJA 5DM71 5IP7L 2PVXA 1BFYA 2PMZP 2BE5D 1NNQA 4AI1A 1VZHA 3LWQB 2AQCA 3GTQL 1NXGA 3PO2L 4E6YA 4A3LL 2VUML 3PZAA 2RDVA 3QQCE 2R93L 5GAEc 1RDGA 1BRFA 1QCVA 2PPTA 2A6HD 3JR7A 3LWPB 1NXEA 1B71A 1PFYA 1Z92B 3P8BA 3H0GL 2PSMC 4AR3A 1IU5A 2MS3A 3LNLA 2CR8A 5RXNA 1RWDA 3QVDA 2APOB 4A3BL 3MSUA 4AR4A 4BY1L 2PYAA 5H1Sc 1CADA 3CQZL 3HOUL 2V0EA 8RXNA 3S1ML 5C3EL 4A3IL 1LKPA 7RXNA 3J7Y1 5GADc 3HJWB 3PWFA 5GAGc 1RYQA 1BQ9A 4POGA 3RZOL 2GMGA 5K2ME 4AHWA 3PL5A 3PKIA 2JA5L 2NVXL 3I4ML 2AYJA 1PFVA 2O5JD 5MFZA 1S30A 3FKIL 5AI2A 4YWLA 4ZN3B 2B5ID 2A69D 4B8CD 2C6AA 3MQKB 3KYYA 1IW7D 4C3JL 4POFA 3ZG6A 6RXNA 2ERSA 5MLC3 5IY0A 4AHYA 3PO3L 1BE7A 2ERJA 1R0FA 3HOYL 5AN9H 3WWNB 3SS2A 1T9OA 4A93L 3HAXC 4A3JL 4AR6A 1TWGL 2JI1A 3S1RL 2NVYL 2RFKB 1RDVA 1YK4A 1Y1WL 1PFUA 3B0AB 1QYBA 2QL0A 2E2HL 1T9QA 5EINC 5GAHc 3B08B 3FDJA 2JI2A 4A3FL 4LHLA 2XJQA 4BXXL 4TPUA 2A68D 1DVBA 2Y0SP 1VZIA 1RYTA 3H9CA 2KKDA 2NVTL 5IYDL 1PZXA 3GTKL 1R0HA 1LTLA 2M6OA 4V196 4C2M1 1OWBA 1PFWA 3MPSA 3RYGA 3RZDL 3J7Z1 1H7VA 1I6HL 1B13A 2HVYC 5FLML 1E8JA 2C6BA 1YV1A 5M5WL 1SFOL 2XJVA 5IP9L 1VZGA 3NFPI 1FHMA 3GTOL 5C44L 1IRNA 2Z3QB 4ME3A 2A6ED 1B2JA 1S2ZA 4WFN1 1QQTA 1YUXA 3S1NL 1TWHL 2XJPA 5IYCL 3KYUA 1OWCA 1IU6A 4AHZA 1TWCL 1WJVA 4ZN1B 5MF6A 1YUZA 1TWFL 2NYDA 4XXBB 3IU3I 2E2JL 3S15L 3HOZL 1B2OA 5M5XL 5DM61 4XGHA 2K2DA 3H3VM 4A3CL 3LWVB 5M3ML 3KYVA 4AYBP 2V3BB 5M3FL 3HKZP 1R9TL 3H99A 5JVG1 2M4VA 2PVEA 4LHNA 4TVMA 3K35A 4C3IL 5M5YL 1DX8A 3S14L 2E2IL 2JA7L 2XJTA 2LCQA 2L0ZA 2NVQL 3S17L 2M6PA 3RZTA 2JI3A 5EIOC 2CKCA 3S2HL 2B63L 4AHXA 2R92L 1FHHA 2XJRA 3KYXA 3LWRB 3PIP1 4UY81 2AUSB 3WWLA 5FJ8L 3LWOB 3PIO1 5AI3A 1T9PA 4JAGA 4YWMA 1F4LA 4JAEA 5JVH1 3A44A 1SMWA 1LKMA 1RB9A 1VCXA 2CKAA 2WAQP 1R0IA 5MGNA 5C4XL 2R7ZL 2VL6A 4A3KL 4JADA 2ZIXA 2HR5A 3K7AL 2KN9A 3M4OL 3S1QL 3I4NL 1SMMA 1SMUA 3M3YL 3GTML 2Z3RB 1C09A 3HOVL 4U671 3GTPL 1R0GA 3P2AA 3H9BA 4G6BA 1IROA 4A3DL 4A3EL 1BQ8A 3GTLL 2M4YA 1ODHA 1CAAA 3VPBE 2JA8L 3HJYB 3S2DL 5IYBL 4GS7D 4AI0A 3RZ6A 3HOWL 2EY4E 2JA6L 4X6AL 1R0JA 1ZRPA 2J9UB 1JYBA 4BY7L 2XJSA 1Y1VL 1I3QL 4A3GL 1WCML 3H97A
chains in the Genus database with same CATH topology
4BY1L 2Y0SP 5C4JL 1K83L 4Y7NL 3S2HL 2YU9L 2B63L 3CQZL 1I50L 2NVTL 5IYDL 3HOUL 3GTKL 3HOXL 2R92L 3S1ML 5C3EL 3S16L 4A3IL 4C2M1 4QIWP 1TWAL 5FJ8L 3RZOL 3RZDL 1I6HL 3GTGL 5FLML 2JA5L 2NVXL 3I4ML 4BBRL 5M5WL 1SFOL 4BBSL 5IP9L 2WAQP 5C4XL 4Y52L 3GTOL 2R7ZL 5C44L 4A3ML 3FKIL 2WB1P 4A3KL 4C3HL 3GTJL 4C3JL 5IP7L 3K7AL 3S1NL 1TWHL 2PMZP 5IYCL 3M4OL 3S1QL 3I4NL 3M3YL 3GTML 3HOVL 3GTPL 3PO3L 1TWCL 3HOYL 3GTQL 1TWFL 3PO2L 4A3DL 2E2JL 3S15L 4A3EL 4A93L 3HOZL 4A3LL 3GTLL 5M5XL 2VUML 4A3JL 3H3VM 4A3CL 2JA8L 5M3ML 3S2DL 2R93L 1TWGL 3S1RL 2NVYL 5IYBL 4AYBP 5M3FL 1Y1WL 3HKZP 1R9TL 3HOWL 3H0GL 2E2HL 4C3IL 5M5YL 2JA6L 4X6AL 4A3FL 4BY7L 3S14L 1Y1VL 1I3QL 4A3GL 1WCML 4BXXL 2E2IL 2JA7L 2NVQL 4A3BL 3S17L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BY1 L;  2Y0S P;  5C4J L;  1K83 L;  4Y7N L;  3S2H L;  2YU9 L;  2B63 L;  3CQZ L;  1I50 L;  2NVT L;  5IYD L;  3HOU L;  3GTK L;  3HOX L;  2R92 L;  3S1M L;  5C3E L;  3S16 L;  4A3I L;  4C2M 1;  4QIW P;  1TWA L;  5FJ8 L;  3RZO L;  3RZD L;  1I6H L;  3GTG L;  5FLM L;  2JA5 L;  2NVX L;  3I4M L;  4BBR L;  5M5W L;  1SFO L;  4BBS L;  5IP9 L;  2WAQ P;  5C4X L;  4Y52 L;  3GTO L;  2R7Z L;  5C44 L;  4A3M L;  3FKI L;  2WB1 P;  4A3K L;  4C3H L;  3GTJ L;  4C3J L;  5IP7 L;  3K7A L;  3S1N L;  1TWH L;  2PMZ P;  5IYC L;  3M4O L;  3S1Q L;  3I4N L;  3M3Y L;  3GTM L;  3HOV L;  3GTP L;  3PO3 L;  1TWC L;  3HOY L;  3GTQ L;  1TWF L;  3PO2 L;  4A3D L;  2E2J L;  3S15 L;  4A3E L;  4A93 L;  3HOZ L;  4A3L L;  3GTL L;  5M5X L;  2VUM L;  4A3J L;  3H3V M;  4A3C L;  2JA8 L;  5M3M L;  3S2D L;  2R93 L;  1TWG L;  3S1R L;  2NVY L;  5IYB L;  4AYB P;  5M3F L;  1Y1W L;  3HKZ P;  1R9T L;  3HOW L;  3H0G L;  2E2H L;  4C3I L;  5M5Y L;  2JA6 L;  4X6A L;  4A3F L;  4BY7 L;  3S14 L;  1Y1V L;  1I3Q L;  4A3G L;  1WCM L;  4BXX L;  2E2I L;  2JA7 L;  2NVQ L;  4A3B L;  3S17 L; 
#chains in the Genus database with same CATH topology
 5C4J L;  1K83 L;  4Y7N L;  2YU9 L;  1YK5 A;  1S24 A;  2V0F A;  1I50 L;  4K9F A;  2DSX A;  3HOX L;  3S16 L;  4QIW P;  1TWA L;  2H12 A;  4RXN A;  3LPE B;  4AI2 A;  3GTG L;  4JAF A;  3KYW A;  4BBR L;  4BBS L;  4Y52 L;  4AR5 A;  4A3M L;  2WB1 P;  4AI3 A;  1LKO A;  4C3H L;  1P7P A;  2XJU A;  5MFP A;  3GTJ L;  3PKJ A;  5DM7 1;  5IP7 L;  2PVX A;  1BFY A;  2PMZ P;  2BE5 D;  1NNQ A;  4AI1 A;  1VZH A;  3LWQ B;  2AQC A;  3GTQ L;  1NXG A;  3PO2 L;  4E6Y A;  4A3L L;  2VUM L;  3PZA A;  2RDV A;  3QQC E;  2R93 L;  5GAE c;  1RDG A;  1BRF A;  1QCV A;  2PPT A;  2A6H D;  3JR7 A;  3LWP B;  1NXE A;  1B71 A;  1PFY A;  1Z92 B;  3P8B A;  3H0G L;  2PSM C;  4AR3 A;  1IU5 A;  2MS3 A;  3LNL A;  2CR8 A;  5RXN A;  1RWD A;  3QVD A;  2APO B;  4A3B L;  3MSU A;  4AR4 A;  4BY1 L;  2PYA A;  5H1S c;  1CAD A;  3CQZ L;  3HOU L;  2V0E A;  8RXN A;  3S1M L;  5C3E L;  4A3I L;  1LKP A;  7RXN A;  3J7Y 1;  5GAD c;  3HJW B;  3PWF A;  5GAG c;  1RYQ A;  1BQ9 A;  4POG A;  3RZO L;  2GMG A;  5K2M E;  4AHW A;  3PL5 A;  3PKI A;  2JA5 L;  2NVX L;  3I4M L;  2AYJ A;  1PFV A;  2O5J D;  5MFZ A;  1S30 A;  3FKI L;  5AI2 A;  4YWL A;  4ZN3 B;  2B5I D;  2A69 D;  4B8C D;  2C6A A;  3MQK B;  3KYY A;  1IW7 D;  4C3J L;  4POF A;  3ZG6 A;  6RXN A;  2ERS A;  5MLC 3;  5IY0 A;  4AHY A;  3PO3 L;  1BE7 A;  2ERJ A;  1R0F A;  3HOY L;  5AN9 H;  3WWN B;  3SS2 A;  1T9O A;  4A93 L;  3HAX C;  4A3J L;  4AR6 A;  1TWG L;  2JI1 A;  3S1R L;  2NVY L;  2RFK B;  1RDV A;  1YK4 A;  1Y1W L;  1PFU A;  3B0A B;  1QYB A;  2QL0 A;  2E2H L;  1T9Q A;  5EIN C;  5GAH c;  3B08 B;  3FDJ A;  2JI2 A;  4A3F L;  4LHL A;  2XJQ A;  4BXX L;  4TPU A;  2A68 D;  1DVB A;  2Y0S P;  1VZI A;  1RYT A;  3H9C A;  2KKD A;  2NVT L;  5IYD L;  1PZX A;  3GTK L;  1R0H A;  1LTL A;  2M6O A;  4V19 6;  4C2M 1;  1OWB A;  1PFW A;  3MPS A;  3RYG A;  3RZD L;  3J7Z 1;  1H7V A;  1I6H L;  1B13 A;  2HVY C;  5FLM L;  1E8J A;  2C6B A;  1YV1 A;  5M5W L;  1SFO L;  2XJV A;  5IP9 L;  1VZG A;  3NFP I;  1FHM A;  3GTO L;  5C44 L;  1IRN A;  2Z3Q B;  4ME3 A;  2A6E D;  1B2J A;  1S2Z A;  4WFN 1;  1QQT A;  1YUX A;  3S1N L;  1TWH L;  2XJP A;  5IYC L;  3KYU A;  1OWC A;  1IU6 A;  4AHZ A;  1TWC L;  1WJV A;  4ZN1 B;  5MF6 A;  1YUZ A;  1TWF L;  2NYD A;  4XXB B;  3IU3 I;  2E2J L;  3S15 L;  3HOZ L;  1B2O A;  5M5X L;  5DM6 1;  4XGH A;  2K2D A;  3H3V M;  4A3C L;  3LWV B;  5M3M L;  3KYV A;  4AYB P;  2V3B B;  5M3F L;  3HKZ P;  1R9T L;  3H99 A;  5JVG 1;  2M4V A;  2PVE A;  4LHN A;  4TVM A;  3K35 A;  4C3I L;  5M5Y L;  1DX8 A;  3S14 L;  2E2I L;  2JA7 L;  2XJT A;  2LCQ A;  2L0Z A;  2NVQ L;  3S17 L;  2M6P A;  3RZT A;  2JI3 A;  5EIO C;  2CKC A;  3S2H L;  2B63 L;  4AHX A;  2R92 L;  1FHH A;  2XJR A;  3KYX A;  3LWR B;  3PIP 1;  4UY8 1;  2AUS B;  3WWL A;  5FJ8 L;  3LWO B;  3PIO 1;  5AI3 A;  1T9P A;  4JAG A;  4YWM A;  1F4L A;  4JAE A;  5JVH 1;  3A44 A;  1SMW A;  1LKM A;  1RB9 A;  1VCX A;  2CKA A;  2WAQ P;  1R0I A;  5MGN A;  5C4X L;  2R7Z L;  2VL6 A;  4A3K L;  4JAD A;  2ZIX A;  2HR5 A;  3K7A L;  2KN9 A;  3M4O L;  3S1Q L;  3I4N L;  1SMM A;  1SMU A;  3M3Y L;  3GTM L;  2Z3R B;  1C09 A;  3HOV L;  4U67 1;  3GTP L;  1R0G A;  3P2A A;  3H9B A;  4G6B A;  1IRO A;  4A3D L;  4A3E L;  1BQ8 A;  3GTL L;  2M4Y A;  1ODH A;  1CAA A;  3VPB E;  2JA8 L;  3HJY B;  3S2D L;  5IYB L;  4GS7 D;  4AI0 A;  3RZ6 A;  3HOW L;  2EY4 E;  2JA6 L;  4X6A L;  1R0J A;  1ZRP A;  2J9U B;  1JYB A;  4BY7 L;  2XJS A;  1Y1V L;  1I3Q L;  4A3G L;  1WCM L;  3H97 A; 
#chains in the Genus database with same CATH homology
 4BY1 L;  2Y0S P;  5C4J L;  1K83 L;  4Y7N L;  3S2H L;  2YU9 L;  2B63 L;  3CQZ L;  1I50 L;  2NVT L;  5IYD L;  3HOU L;  3GTK L;  3HOX L;  2R92 L;  3S1M L;  5C3E L;  3S16 L;  4A3I L;  4C2M 1;  4QIW P;  1TWA L;  5FJ8 L;  3RZO L;  3RZD L;  1I6H L;  3GTG L;  5FLM L;  2JA5 L;  2NVX L;  3I4M L;  4BBR L;  5M5W L;  1SFO L;  4BBS L;  5IP9 L;  2WAQ P;  5C4X L;  4Y52 L;  3GTO L;  2R7Z L;  5C44 L;  4A3M L;  3FKI L;  2WB1 P;  4A3K L;  4C3H L;  3GTJ L;  4C3J L;  5IP7 L;  3K7A L;  3S1N L;  1TWH L;  2PMZ P;  5IYC L;  3M4O L;  3S1Q L;  3I4N L;  3M3Y L;  3GTM L;  3HOV L;  3GTP L;  3PO3 L;  1TWC L;  3HOY L;  3GTQ L;  1TWF L;  3PO2 L;  4A3D L;  2E2J L;  3S15 L;  4A3E L;  4A93 L;  3HOZ L;  4A3L L;  3GTL L;  5M5X L;  2VUM L;  4A3J L;  3H3V M;  4A3C L;  2JA8 L;  5M3M L;  3S2D L;  2R93 L;  1TWG L;  3S1R L;  2NVY L;  5IYB L;  4AYB P;  5M3F L;  1Y1W L;  3HKZ P;  1R9T L;  3HOW L;  3H0G L;  2E2H L;  4C3I L;  5M5Y L;  2JA6 L;  4X6A L;  4A3F L;  4BY7 L;  3S14 L;  1Y1V L;  1I3Q L;  4A3G L;  1WCM L;  4BXX L;  2E2I L;  2JA7 L;  2NVQ L;  4A3B L;  3S17 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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