4A3LL

Rna polymerase ii initial transcribing complex with a 7nt dna-rna hybrid and soaked with ampcpp
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4a3lL00
3H3VM 3PO3L 4A3KL 1SFOL 1I3QL 4BY7L 5IYBL 4AYBP 2R92L 4C3IL 1R9TL 1K83L 2R7ZL 3GTQL 1TWGL 4C2M1 3HOXL 2JA6L 5C4JL 3FKIL 5IP9L 2JA8L 3GTML 3GTOL 1TWAL 1TWHL 3M3YL 3HOYL 4C3HL 2E2IL 3S1QL 4A93L 2WAQP 5M5WL 3GTKL 2YU9L 3GTLL 3M4OL 3I4ML 4A3BL 4BBSL 2NVXL 5M3FL 1I6HL 2NVQL 4A3DL 4A3EL 3RZOL 1TWCL 2JA7L 4A3LL 5C4XL 4Y52L 1Y1WL 5M5YL 4A3JL 3GTPL 4C3JL 4A3GL 2WB1P 3S1ML 1I50L 4BBRL 3PO2L 4A3ML 2NVYL 4X6AL 1TWFL 5M5XL 4A3IL 3GTGL 3S2HL 4A3CL 2E2HL 3S14L 2VUML 5M3ML 1WCML 3S16L 3S1RL 3RZDL 2PMZP 3K7AL 3HKZP 2B63L 5IP7L 3HOWL 5C3EL 5FJ8L 5FLML 4BY1L 3HOVL 4Y7NL 1Y1VL 5C44L 3S17L 3S2DL 2Y0SP 3HOUL 2R93L 3HOZL 4QIWP 4BXXL 2JA5L 2NVTL 3H0GL 5IYDL 5IYCL 3S1NL 3I4NL 3GTJL 3S15L 3CQZL 4A3FL 2E2JL
chains in the Genus database with same CATH superfamily
3PO3L 2O5JD 1S30A 1SFOL 2RDVA 1I3QL 3KYUA 1IU5A 3HJWB 1R9TL 3HOXL 5C4JL 5IP9L 2JA8L 1VZIA 1TWHL 3M3YL 1SMWA 2V0EA 2M4YA 4A93L 2WAQP 2NYDA 3M4OL 4A3BL 5M3FL 3J7Y1 1WJVA 1IU6A 5M5YL 1R0HA 2LCQA 2BE5D 3J7Z1 4C3JL 2WB1P 4AR4A 3PIO1 4BBRL 1SMMA 5GAGc 4G6BA 1TWFL 5DM71 2XJPA 4GS7D 1RWDA 2ZIXA 1CADA 3LWVB 3FDJA 5DM61 4JADA 3RZ6A 1QQTA 3S1RL 1FHMA 3HKZP 2B63L 4TPUA 2MS3A 5C3EL 1R0GA 3HJYB 4ZN3B 2PVXA 5C44L 4AHWA 2B5ID 3HOUL 3SS2A 2K2DA 4ZN1B 5MLC3 3HOZL 5JVH1 4AI3A 2AYJA 3KYYA 2PYAA 5GADc 1NXGA 5IYDL 4JAFA 1BQ9A 3S1NL 3I4NL 3PKJA 2XJVA 3H3VM 2C6BA 1VZHA 4A3KL 2A6HD 5IYBL 4AR5A 7RXNA 3WWNB 1TWGL 4C2M1 2JA6L 4YWMA 3FKIL 3GTML 1TWAL 2ERJA 1LTLA 3QQCE 1LKPA 1SMUA 3HOYL 3JR7A 2E2IL 5M5WL 4LHLA 3GTKL 3GTLL 4BBSL 5IY0A 2NVXL 3RZTA 2NVQL 4A3DL 4A3EL 1IRNA 1TWCL 2DSXA 1R0FA 3IU3I 4POFA 2PSMC 2EY4E 3S1ML 1I50L 2HVYC 3LWQB 3KYXA 4YWLA 3PO2L 4A3ML 4AR3A 2NVYL 4X6AL 4A3IL 3GTGL 3S2HL 4A3CL 1PFWA 2A6ED 2E2HL 5EINC 1LKMA 2L0ZA 3S16L 3RZDL 2VL6A 4V196 4AI2A 5IP7L 3HOWL 1NNQA 1BFYA 5FLML 4BY1L 2ERSA 1S2ZA 1PFVA 1Y1VL 4TVMA 3QVDA 3S17L 2Y0SP 4RXNA 3H97A 2CKCA 1RYQA 1LKOA 3KYVA 2Z3RB 2CKAA 5IYCL 4U671 2C6AA 2CR8A 3S15L 4UY81 2HR5A 1NXEA 4A3FL 1YK5A 4WFN1 2PPTA 2XJTA 2RFKB 4AI0A 2KN9A 1T9PA 1PZXA 1R0IA 3PKIA 1B71A 4BY7L 1QYBA 4AYBP 3MSUA 2XJUA 1E8JA 2R92L 4C3IL 1K83L 3GTQL 3LPEB 3GTOL 1B2JA 1DVBA 3PZAA 3MPSA 4C3HL 2Z3QB 5AN9H 3LWPB 5MFPA 5EIOC 4AHXA 1Z92B 2XJSA 1JYBA 1IROA 1YK4A 5RXNA 3RZOL 1BE7A 1OWBA 2JA7L 1Y1WL 3B08B 3GTPL 1CAAA 4K9FA 4A3GL 2A68D 2H12A 1BQ8A 2QL0A 1RDVA 5GAEc 5MGNA 5M5XL 1P7PA 1B2OA 5K2ME 4AI1A 3H9BA 2JI1A 2M6OA 1DX8A 1YV1A 1QCVA 2VUML 6RXNA 3LWOB 1WCML 1IW7D 1BRFA 2PMZP 4POGA 1RDGA 5FJ8L 2GMGA 3HOVL 1FHHA 1F4LA 8RXNA 1RYTA 5AI3A 2M6PA 2R93L 3K35A 3PWFA 2PVEA 4QIWP 2J9UB 3RYGA 4ME3A 2JA5L 3H0GL 1C09A 1S24A 3H99A 3P8BA 5JVG1 3CQZL 3P2AA 2M4VA 1ODHA 2E2JL 1PFUA 3NFPI 5H1Sc 4JAEA 2V3BB 3LWRB 2R7ZL 2A69D 2XJQA 1PFYA 5GAHc 3S1QL 2YU9L 2APOB 3VPBE 1I6HL 4XXBB 1H7VA 2V0FA 4A3LL 5C4XL 4Y52L 1T9QA 4A3JL 4JAGA 2AUSB 2JI2A 1R0JA 2JI3A 5MF6A 3WWLA 1ZRPA 1VCXA 3KYWA 3A44A 3S14L 1YUXA 5M3ML 1T9OA 1YUZA 2XJRA 3B0AB 3K7AL 4LHNA 4B8CD 1OWCA 3PL5A 4Y7NL 4E6YA 1RB9A 4AR6A 3PIP1 3S2DL 3H9CA 4AHYA 3HAXC 4BXXL 4AHZA 2NVTL 2AQCA 3MQKB 1B13A 1VZGA 4XGHA 3GTJL 5MFZA 3LNLA 5AI2A 3ZG6A 2KKDA 3I4ML
chains in the Genus database with same CATH topology
3H3VM 3PO3L 4A3KL 1SFOL 1I3QL 4BY7L 5IYBL 4AYBP 2R92L 4C3IL 1R9TL 1K83L 2R7ZL 3GTQL 1TWGL 4C2M1 3HOXL 2JA6L 5C4JL 3FKIL 5IP9L 2JA8L 3GTML 3GTOL 1TWAL 1TWHL 3M3YL 3HOYL 4C3HL 2E2IL 3S1QL 4A93L 2WAQP 5M5WL 3GTKL 2YU9L 3GTLL 3M4OL 3I4ML 4A3BL 4BBSL 2NVXL 5M3FL 1I6HL 2NVQL 4A3DL 4A3EL 3RZOL 1TWCL 2JA7L 4A3LL 5C4XL 4Y52L 1Y1WL 5M5YL 4A3JL 3GTPL 4C3JL 4A3GL 2WB1P 3S1ML 1I50L 4BBRL 3PO2L 4A3ML 2NVYL 4X6AL 1TWFL 5M5XL 4A3IL 3GTGL 3S2HL 4A3CL 2E2HL 3S14L 2VUML 5M3ML 1WCML 3S16L 3S1RL 3RZDL 2PMZP 3K7AL 3HKZP 2B63L 5IP7L 3HOWL 5C3EL 5FJ8L 5FLML 4BY1L 3HOVL 4Y7NL 1Y1VL 5C44L 3S17L 3S2DL 2Y0SP 3HOUL 2R93L 3HOZL 4QIWP 4BXXL 2JA5L 2NVTL 3H0GL 5IYDL 5IYCL 3S1NL 3I4NL 3GTJL 3S15L 3CQZL 4A3FL 2E2JL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H3V M;  3PO3 L;  4A3K L;  1SFO L;  1I3Q L;  4BY7 L;  5IYB L;  4AYB P;  2R92 L;  4C3I L;  1R9T L;  1K83 L;  2R7Z L;  3GTQ L;  1TWG L;  4C2M 1;  3HOX L;  2JA6 L;  5C4J L;  3FKI L;  5IP9 L;  2JA8 L;  3GTM L;  3GTO L;  1TWA L;  1TWH L;  3M3Y L;  3HOY L;  4C3H L;  2E2I L;  3S1Q L;  4A93 L;  2WAQ P;  5M5W L;  3GTK L;  2YU9 L;  3GTL L;  3M4O L;  3I4M L;  4A3B L;  4BBS L;  2NVX L;  5M3F L;  1I6H L;  2NVQ L;  4A3D L;  4A3E L;  3RZO L;  1TWC L;  2JA7 L;  4A3L L;  5C4X L;  4Y52 L;  1Y1W L;  5M5Y L;  4A3J L;  3GTP L;  4C3J L;  4A3G L;  2WB1 P;  3S1M L;  1I50 L;  4BBR L;  3PO2 L;  4A3M L;  2NVY L;  4X6A L;  1TWF L;  5M5X L;  4A3I L;  3GTG L;  3S2H L;  4A3C L;  2E2H L;  3S14 L;  2VUM L;  5M3M L;  1WCM L;  3S16 L;  3S1R L;  3RZD L;  2PMZ P;  3K7A L;  3HKZ P;  2B63 L;  5IP7 L;  3HOW L;  5C3E L;  5FJ8 L;  5FLM L;  4BY1 L;  3HOV L;  4Y7N L;  1Y1V L;  5C44 L;  3S17 L;  3S2D L;  2Y0S P;  3HOU L;  2R93 L;  3HOZ L;  4QIW P;  4BXX L;  2JA5 L;  2NVT L;  3H0G L;  5IYD L;  5IYC L;  3S1N L;  3I4N L;  3GTJ L;  3S15 L;  3CQZ L;  4A3F L;  2E2J L; 
#chains in the Genus database with same CATH topology
 3PO3 L;  2O5J D;  1S30 A;  1SFO L;  2RDV A;  1I3Q L;  3KYU A;  1IU5 A;  3HJW B;  1R9T L;  3HOX L;  5C4J L;  5IP9 L;  2JA8 L;  1VZI A;  1TWH L;  3M3Y L;  1SMW A;  2V0E A;  2M4Y A;  4A93 L;  2WAQ P;  2NYD A;  3M4O L;  4A3B L;  5M3F L;  3J7Y 1;  1WJV A;  1IU6 A;  5M5Y L;  1R0H A;  2LCQ A;  2BE5 D;  3J7Z 1;  4C3J L;  2WB1 P;  4AR4 A;  3PIO 1;  4BBR L;  1SMM A;  5GAG c;  4G6B A;  1TWF L;  5DM7 1;  2XJP A;  4GS7 D;  1RWD A;  2ZIX A;  1CAD A;  3LWV B;  3FDJ A;  5DM6 1;  4JAD A;  3RZ6 A;  1QQT A;  3S1R L;  1FHM A;  3HKZ P;  2B63 L;  4TPU A;  2MS3 A;  5C3E L;  1R0G A;  3HJY B;  4ZN3 B;  2PVX A;  5C44 L;  4AHW A;  2B5I D;  3HOU L;  3SS2 A;  2K2D A;  4ZN1 B;  5MLC 3;  3HOZ L;  5JVH 1;  4AI3 A;  2AYJ A;  3KYY A;  2PYA A;  5GAD c;  1NXG A;  5IYD L;  4JAF A;  1BQ9 A;  3S1N L;  3I4N L;  3PKJ A;  2XJV A;  3H3V M;  2C6B A;  1VZH A;  4A3K L;  2A6H D;  5IYB L;  4AR5 A;  7RXN A;  3WWN B;  1TWG L;  4C2M 1;  2JA6 L;  4YWM A;  3FKI L;  3GTM L;  1TWA L;  2ERJ A;  1LTL A;  3QQC E;  1LKP A;  1SMU A;  3HOY L;  3JR7 A;  2E2I L;  5M5W L;  4LHL A;  3GTK L;  3GTL L;  4BBS L;  5IY0 A;  2NVX L;  3RZT A;  2NVQ L;  4A3D L;  4A3E L;  1IRN A;  1TWC L;  2DSX A;  1R0F A;  3IU3 I;  4POF A;  2PSM C;  2EY4 E;  3S1M L;  1I50 L;  2HVY C;  3LWQ B;  3KYX A;  4YWL A;  3PO2 L;  4A3M L;  4AR3 A;  2NVY L;  4X6A L;  4A3I L;  3GTG L;  3S2H L;  4A3C L;  1PFW A;  2A6E D;  2E2H L;  5EIN C;  1LKM A;  2L0Z A;  3S16 L;  3RZD L;  2VL6 A;  4V19 6;  4AI2 A;  5IP7 L;  3HOW L;  1NNQ A;  1BFY A;  5FLM L;  4BY1 L;  2ERS A;  1S2Z A;  1PFV A;  1Y1V L;  4TVM A;  3QVD A;  3S17 L;  2Y0S P;  4RXN A;  3H97 A;  2CKC A;  1RYQ A;  1LKO A;  3KYV A;  2Z3R B;  2CKA A;  5IYC L;  4U67 1;  2C6A A;  2CR8 A;  3S15 L;  4UY8 1;  2HR5 A;  1NXE A;  4A3F L;  1YK5 A;  4WFN 1;  2PPT A;  2XJT A;  2RFK B;  4AI0 A;  2KN9 A;  1T9P A;  1PZX A;  1R0I A;  3PKI A;  1B71 A;  4BY7 L;  1QYB A;  4AYB P;  3MSU A;  2XJU A;  1E8J A;  2R92 L;  4C3I L;  1K83 L;  3GTQ L;  3LPE B;  3GTO L;  1B2J A;  1DVB A;  3PZA A;  3MPS A;  4C3H L;  2Z3Q B;  5AN9 H;  3LWP B;  5MFP A;  5EIO C;  4AHX A;  1Z92 B;  2XJS A;  1JYB A;  1IRO A;  1YK4 A;  5RXN A;  3RZO L;  1BE7 A;  1OWB A;  2JA7 L;  1Y1W L;  3B08 B;  3GTP L;  1CAA A;  4K9F A;  4A3G L;  2A68 D;  2H12 A;  1BQ8 A;  2QL0 A;  1RDV A;  5GAE c;  5MGN A;  5M5X L;  1P7P A;  1B2O A;  5K2M E;  4AI1 A;  3H9B A;  2JI1 A;  2M6O A;  1DX8 A;  1YV1 A;  1QCV A;  2VUM L;  6RXN A;  3LWO B;  1WCM L;  1IW7 D;  1BRF A;  2PMZ P;  4POG A;  1RDG A;  5FJ8 L;  2GMG A;  3HOV L;  1FHH A;  1F4L A;  8RXN A;  1RYT A;  5AI3 A;  2M6P A;  2R93 L;  3K35 A;  3PWF A;  2PVE A;  4QIW P;  2J9U B;  3RYG A;  4ME3 A;  2JA5 L;  3H0G L;  1C09 A;  1S24 A;  3H99 A;  3P8B A;  5JVG 1;  3CQZ L;  3P2A A;  2M4V A;  1ODH A;  2E2J L;  1PFU A;  3NFP I;  5H1S c;  4JAE A;  2V3B B;  3LWR B;  2R7Z L;  2A69 D;  2XJQ A;  1PFY A;  5GAH c;  3S1Q L;  2YU9 L;  2APO B;  3VPB E;  1I6H L;  4XXB B;  1H7V A;  2V0F A;  4A3L L;  5C4X L;  4Y52 L;  1T9Q A;  4A3J L;  4JAG A;  2AUS B;  2JI2 A;  1R0J A;  2JI3 A;  5MF6 A;  3WWL A;  1ZRP A;  1VCX A;  3KYW A;  3A44 A;  3S14 L;  1YUX A;  5M3M L;  1T9O A;  1YUZ A;  2XJR A;  3B0A B;  3K7A L;  4LHN A;  4B8C D;  1OWC A;  3PL5 A;  4Y7N L;  4E6Y A;  1RB9 A;  4AR6 A;  3PIP 1;  3S2D L;  3H9C A;  4AHY A;  3HAX C;  4BXX L;  4AHZ A;  2NVT L;  2AQC A;  3MQK B;  1B13 A;  1VZG A;  4XGH A;  3GTJ L;  5MFZ A;  3LNL A;  5AI2 A;  3ZG6 A;  2KKD A;  3I4M L; 
#chains in the Genus database with same CATH homology
 3H3V M;  3PO3 L;  4A3K L;  1SFO L;  1I3Q L;  4BY7 L;  5IYB L;  4AYB P;  2R92 L;  4C3I L;  1R9T L;  1K83 L;  2R7Z L;  3GTQ L;  1TWG L;  4C2M 1;  3HOX L;  2JA6 L;  5C4J L;  3FKI L;  5IP9 L;  2JA8 L;  3GTM L;  3GTO L;  1TWA L;  1TWH L;  3M3Y L;  3HOY L;  4C3H L;  2E2I L;  3S1Q L;  4A93 L;  2WAQ P;  5M5W L;  3GTK L;  2YU9 L;  3GTL L;  3M4O L;  3I4M L;  4A3B L;  4BBS L;  2NVX L;  5M3F L;  1I6H L;  2NVQ L;  4A3D L;  4A3E L;  3RZO L;  1TWC L;  2JA7 L;  4A3L L;  5C4X L;  4Y52 L;  1Y1W L;  5M5Y L;  4A3J L;  3GTP L;  4C3J L;  4A3G L;  2WB1 P;  3S1M L;  1I50 L;  4BBR L;  3PO2 L;  4A3M L;  2NVY L;  4X6A L;  1TWF L;  5M5X L;  4A3I L;  3GTG L;  3S2H L;  4A3C L;  2E2H L;  3S14 L;  2VUM L;  5M3M L;  1WCM L;  3S16 L;  3S1R L;  3RZD L;  2PMZ P;  3K7A L;  3HKZ P;  2B63 L;  5IP7 L;  3HOW L;  5C3E L;  5FJ8 L;  5FLM L;  4BY1 L;  3HOV L;  4Y7N L;  1Y1V L;  5C44 L;  3S17 L;  3S2D L;  2Y0S P;  3HOU L;  2R93 L;  3HOZ L;  4QIW P;  4BXX L;  2JA5 L;  2NVT L;  3H0G L;  5IYD L;  5IYC L;  3S1N L;  3I4N L;  3GTJ L;  3S15 L;  3CQZ L;  4A3F L;  2E2J L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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