4A3ML

Rna polymerase ii initial transcribing complex with a 4nt dna-rna hybrid and soaked with ampcpp
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4a3mL00
3S16L 3GTML 5C3EL 4A3CL 4BXXL 1WCML 4A3ML 3S14L 2JA6L 4A3KL 1Y1WL 5C4XL 5FJ8L 3S1RL 5M5YL 1TWAL 1R9TL 2JA5L 2NVYL 4A3IL 5M3ML 4AYBP 3HKZP 4C3IL 1K83L 2Y0SP 4QIWP 1SFOL 3GTPL 3S1QL 4X6AL 3HOYL 3H0GL 3S1NL 3RZOL 3CQZL 3S2HL 4A3BL 2WAQP 4A3GL 4A3JL 2B63L 2PMZP 1TWHL 5M5XL 5IYBL 2JA7L 5C4JL 2R93L 1TWCL 3HOZL 5IYDL 5IP9L 4Y7NL 4C3JL 4A3DL 2E2HL 5IYCL 3S17L 4BY7L 4A3LL 3I4ML 4BBSL 3PO3L 3M3YL 2R92L 2JA8L 4A3FL 1Y1VL 2WB1P 3M4OL 3H3VM 3K7AL 5IP7L 3RZDL 2E2IL 2E2JL 3GTGL 3HOUL 2YU9L 1TWFL 4Y52L 4A93L 3S2DL 3PO2L 2NVQL 4BBRL 3GTLL 1TWGL 3S1ML 3FKIL 3I4NL 1I6HL 4C3HL 3S15L 3HOXL 2VUML 2R7ZL 5C44L 3GTKL 5M5WL 4A3EL 3HOWL 5FLML 1I3QL 3GTJL 2NVTL 3HOVL 3GTOL 3GTQL 5M3FL 1I50L 4C2M1 2NVXL 4BY1L
chains in the Genus database with same CATH superfamily
3JR7A 1OWBA 4A3CL 1VZGA 4A3ML 1JYBA 4POGA 1PFVA 4A3KL 3S1RL 8RXNA 4AYBP 3HKZP 2XJSA 2M4YA 3H0GL 3S2HL 1BE7A 1RDGA 2WAQP 2PVXA 1S2ZA 4A3JL 1QQTA 1TWHL 2XJPA 1E8JA 1VCXA 2PPTA 2K2DA 5IYDL 2RFKB 1VZHA 1RDVA 2E2HL 1P7PA 1PFYA 4LHNA 3QQCE 2R92L 2JA8L 4A3FL 3M4OL 4AR3A 2C6AA 3KYUA 5JVH1 4RXNA 3RZDL 3MQKB 2E2JL 1ZRPA 1FHMA 1YUZA 4K9FA 1SMUA 1CADA 1RWDA 2GMGA 2NYDA 2XJRA 3RYGA 2DSXA 2Z3QB 2QL0A 2XJUA 3IU3I 1TWGL 1OWCA 2ZIXA 2CR8A 4JAFA 1SMMA 4B8CD 5FLML 3GTJL 4XXBB 1R0IA 2KN9A 4C2M1 2NVXL 1YV1A 3PL5A 3S16L 3GTML 3PIP1 5C3EL 2AQCA 2JI1A 3S14L 1DX8A 2EY4E 5C4XL 5AN9H 1S30A 5M5YL 2JA5L 2XJTA 3RZTA 1PFWA 5AI2A 4C3IL 3NFPI 2APOB 3HOYL 2HVYC 3S1NL 3RZOL 2LCQA 2BE5D 3H9CA 4A3GL 2JI3A 2V3BB 5GAHc 5GAEc 5M5XL 3LPEB 5DM61 1BQ8A 4WFN1 3PZAA 5C4JL 3HJWB 5MF6A 5IP9L 5IYCL 4JAEA 3S17L 2AUSB 2Z3RB 1LTLA 3RZ6A 1S24A 1B2OA 5IP7L 2E2IL 3A44A 2PVEA 4Y52L 5AI3A 4AI1A 4AR5A 1QYBA 1LKMA 2NVQL 5EIOC 2CKCA 3J7Z1 3S1ML 3I4NL 3PKJA 4AI2A 3S15L 3HOXL 2XJQA 3PKIA 3GTKL 4A3EL 2ERSA 4JADA 3HOVL 2NVTL 4G6BA 3GTOL 5M3FL 1R0JA 5IY0A 1NXEA 1NXGA 3H97A 4AR6A 1LKOA 2PYAA 2KKDA 2JA6L 1CAAA 1Y1WL 2M6OA 5FJ8L 1DVBA 3HJYB 4AI3A 2RDVA 5MFZA 3H99A 1WJVA 1F4LA 4A3IL 5M3ML 3LWQB 2A6HD 3B0AB 3FDJA 1B71A 4LHLA 1SFOL 3LWOB 4UY81 3KYYA 4X6AL 1YUXA 3CQZL 2AYJA 2V0FA 3PWFA 5RXNA 3KYXA 1BQ9A 2PMZP 1T9QA 1IROA 5IYBL 1T9PA 3B08B 2A6ED 3MSUA 1TWCL 4AHYA 1C09A 3HOZL 2XJVA 5H1Sc 4C3JL 4A3DL 2ERJA 2A69D 4BY7L 3ZG6A 4A3LL 2L0ZA 3PO3L 2JI2A 3M3YL 1IRNA 1Y1VL 2WB1P 3H3VM 4U671 4ME3A 2V0EA 1PZXA 2YU9L 1R0FA 3VPBE 4BBRL 1YK5A 3LWVB 3GTLL 5MLC3 4XGHA 3FKIL 3P2AA 1SMWA 4JAGA 1I6HL 4C3HL 3WWNB 1QCVA 4AHXA 3HOWL 1R0GA 1I3QL 4ZN1B 3GTQL 1I50L 2MS3A 1YK4A 1B13A 3H9BA 2B63L 4BY1L 4YWMA 4AHZA 3KYVA 1R0HA 1IU5A 2A68D 4BXXL 4AR4A 1WCML 2C6BA 2B5ID 4YWLA 3LNLA 1FHHA 1IW7D 1TWAL 1R9TL 4POFA 2NVYL 1K83L 2Y0SP 4QIWP 1LKPA 3GTPL 5K2ME 1NNQA 3S1QL 3K35A 1PFUA 4A3BL 3KYWA 1VZIA 5MFPA 1BFYA 6RXNA 4AI0A 1RYTA 1B2JA 2JA7L 4TVMA 4AHWA 3MPSA 2R93L 4Y7NL 1Z92B 5EINC 1H7VA 2HR5A 3SS2A 5GADc 7RXNA 3I4ML 4ZN3B 1BRFA 2CKAA 4BBSL 5JVG1 3P8BA 3K7AL 5MGNA 4E6YA 2J9UB 3PIO1 3GTGL 3HOUL 1TWFL 4V196 4A93L 5GAGc 3S2DL 3PO2L 1IU6A 2PSMC 2VL6A 3LWPB 5DM71 3WWLA 1RB9A 2M6PA 3QVDA 4TPUA 2M4VA 2VUML 1T9OA 2H12A 2R7ZL 5C44L 2O5JD 5M5WL 1ODHA 3HAXC 3J7Y1 1RYQA 4GS7D 3LWRB
chains in the Genus database with same CATH topology
3S16L 3GTML 5C3EL 4A3CL 4BXXL 1WCML 4A3ML 3S14L 2JA6L 4A3KL 1Y1WL 5C4XL 5FJ8L 3S1RL 5M5YL 1TWAL 1R9TL 2JA5L 2NVYL 4A3IL 5M3ML 4AYBP 3HKZP 4C3IL 1K83L 2Y0SP 4QIWP 1SFOL 3GTPL 3S1QL 4X6AL 3HOYL 3H0GL 3S1NL 3RZOL 3CQZL 3S2HL 4A3BL 2WAQP 4A3GL 4A3JL 2B63L 2PMZP 1TWHL 5M5XL 5IYBL 2JA7L 5C4JL 2R93L 1TWCL 3HOZL 5IYDL 5IP9L 4Y7NL 4C3JL 4A3DL 2E2HL 5IYCL 3S17L 4BY7L 4A3LL 3I4ML 4BBSL 3PO3L 3M3YL 2R92L 2JA8L 4A3FL 1Y1VL 2WB1P 3M4OL 3H3VM 3K7AL 5IP7L 3RZDL 2E2IL 2E2JL 3GTGL 3HOUL 2YU9L 1TWFL 4Y52L 4A93L 3S2DL 3PO2L 2NVQL 4BBRL 3GTLL 1TWGL 3S1ML 3FKIL 3I4NL 1I6HL 4C3HL 3S15L 3HOXL 2VUML 2R7ZL 5C44L 3GTKL 5M5WL 4A3EL 3HOWL 5FLML 1I3QL 3GTJL 2NVTL 3HOVL 3GTOL 3GTQL 5M3FL 1I50L 4C2M1 2NVXL 4BY1L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S16 L;  3GTM L;  5C3E L;  4A3C L;  4BXX L;  1WCM L;  4A3M L;  3S14 L;  2JA6 L;  4A3K L;  1Y1W L;  5C4X L;  5FJ8 L;  3S1R L;  5M5Y L;  1TWA L;  1R9T L;  2JA5 L;  2NVY L;  4A3I L;  5M3M L;  4AYB P;  3HKZ P;  4C3I L;  1K83 L;  2Y0S P;  4QIW P;  1SFO L;  3GTP L;  3S1Q L;  4X6A L;  3HOY L;  3H0G L;  3S1N L;  3RZO L;  3CQZ L;  3S2H L;  4A3B L;  2WAQ P;  4A3G L;  4A3J L;  2B63 L;  2PMZ P;  1TWH L;  5M5X L;  5IYB L;  2JA7 L;  5C4J L;  2R93 L;  1TWC L;  3HOZ L;  5IYD L;  5IP9 L;  4Y7N L;  4C3J L;  4A3D L;  2E2H L;  5IYC L;  3S17 L;  4BY7 L;  4A3L L;  3I4M L;  4BBS L;  3PO3 L;  3M3Y L;  2R92 L;  2JA8 L;  4A3F L;  1Y1V L;  2WB1 P;  3M4O L;  3H3V M;  3K7A L;  5IP7 L;  3RZD L;  2E2I L;  2E2J L;  3GTG L;  3HOU L;  2YU9 L;  1TWF L;  4Y52 L;  4A93 L;  3S2D L;  3PO2 L;  2NVQ L;  4BBR L;  3GTL L;  1TWG L;  3S1M L;  3FKI L;  3I4N L;  1I6H L;  4C3H L;  3S15 L;  3HOX L;  2VUM L;  2R7Z L;  5C44 L;  3GTK L;  5M5W L;  4A3E L;  3HOW L;  5FLM L;  1I3Q L;  3GTJ L;  2NVT L;  3HOV L;  3GTO L;  3GTQ L;  5M3F L;  1I50 L;  4C2M 1;  2NVX L;  4BY1 L; 
#chains in the Genus database with same CATH topology
 3JR7 A;  1OWB A;  4A3C L;  1VZG A;  4A3M L;  1JYB A;  4POG A;  1PFV A;  4A3K L;  3S1R L;  8RXN A;  4AYB P;  3HKZ P;  2XJS A;  2M4Y A;  3H0G L;  3S2H L;  1BE7 A;  1RDG A;  2WAQ P;  2PVX A;  1S2Z A;  4A3J L;  1QQT A;  1TWH L;  2XJP A;  1E8J A;  1VCX A;  2PPT A;  2K2D A;  5IYD L;  2RFK B;  1VZH A;  1RDV A;  2E2H L;  1P7P A;  1PFY A;  4LHN A;  3QQC E;  2R92 L;  2JA8 L;  4A3F L;  3M4O L;  4AR3 A;  2C6A A;  3KYU A;  5JVH 1;  4RXN A;  3RZD L;  3MQK B;  2E2J L;  1ZRP A;  1FHM A;  1YUZ A;  4K9F A;  1SMU A;  1CAD A;  1RWD A;  2GMG A;  2NYD A;  2XJR A;  3RYG A;  2DSX A;  2Z3Q B;  2QL0 A;  2XJU A;  3IU3 I;  1TWG L;  1OWC A;  2ZIX A;  2CR8 A;  4JAF A;  1SMM A;  4B8C D;  5FLM L;  3GTJ L;  4XXB B;  1R0I A;  2KN9 A;  4C2M 1;  2NVX L;  1YV1 A;  3PL5 A;  3S16 L;  3GTM L;  3PIP 1;  5C3E L;  2AQC A;  2JI1 A;  3S14 L;  1DX8 A;  2EY4 E;  5C4X L;  5AN9 H;  1S30 A;  5M5Y L;  2JA5 L;  2XJT A;  3RZT A;  1PFW A;  5AI2 A;  4C3I L;  3NFP I;  2APO B;  3HOY L;  2HVY C;  3S1N L;  3RZO L;  2LCQ A;  2BE5 D;  3H9C A;  4A3G L;  2JI3 A;  2V3B B;  5GAH c;  5GAE c;  5M5X L;  3LPE B;  5DM6 1;  1BQ8 A;  4WFN 1;  3PZA A;  5C4J L;  3HJW B;  5MF6 A;  5IP9 L;  5IYC L;  4JAE A;  3S17 L;  2AUS B;  2Z3R B;  1LTL A;  3RZ6 A;  1S24 A;  1B2O A;  5IP7 L;  2E2I L;  3A44 A;  2PVE A;  4Y52 L;  5AI3 A;  4AI1 A;  4AR5 A;  1QYB A;  1LKM A;  2NVQ L;  5EIO C;  2CKC A;  3J7Z 1;  3S1M L;  3I4N L;  3PKJ A;  4AI2 A;  3S15 L;  3HOX L;  2XJQ A;  3PKI A;  3GTK L;  4A3E L;  2ERS A;  4JAD A;  3HOV L;  2NVT L;  4G6B A;  3GTO L;  5M3F L;  1R0J A;  5IY0 A;  1NXE A;  1NXG A;  3H97 A;  4AR6 A;  1LKO A;  2PYA A;  2KKD A;  2JA6 L;  1CAA A;  1Y1W L;  2M6O A;  5FJ8 L;  1DVB A;  3HJY B;  4AI3 A;  2RDV A;  5MFZ A;  3H99 A;  1WJV A;  1F4L A;  4A3I L;  5M3M L;  3LWQ B;  2A6H D;  3B0A B;  3FDJ A;  1B71 A;  4LHL A;  1SFO L;  3LWO B;  4UY8 1;  3KYY A;  4X6A L;  1YUX A;  3CQZ L;  2AYJ A;  2V0F A;  3PWF A;  5RXN A;  3KYX A;  1BQ9 A;  2PMZ P;  1T9Q A;  1IRO A;  5IYB L;  1T9P A;  3B08 B;  2A6E D;  3MSU A;  1TWC L;  4AHY A;  1C09 A;  3HOZ L;  2XJV A;  5H1S c;  4C3J L;  4A3D L;  2ERJ A;  2A69 D;  4BY7 L;  3ZG6 A;  4A3L L;  2L0Z A;  3PO3 L;  2JI2 A;  3M3Y L;  1IRN A;  1Y1V L;  2WB1 P;  3H3V M;  4U67 1;  4ME3 A;  2V0E A;  1PZX A;  2YU9 L;  1R0F A;  3VPB E;  4BBR L;  1YK5 A;  3LWV B;  3GTL L;  5MLC 3;  4XGH A;  3FKI L;  3P2A A;  1SMW A;  4JAG A;  1I6H L;  4C3H L;  3WWN B;  1QCV A;  4AHX A;  3HOW L;  1R0G A;  1I3Q L;  4ZN1 B;  3GTQ L;  1I50 L;  2MS3 A;  1YK4 A;  1B13 A;  3H9B A;  2B63 L;  4BY1 L;  4YWM A;  4AHZ A;  3KYV A;  1R0H A;  1IU5 A;  2A68 D;  4BXX L;  4AR4 A;  1WCM L;  2C6B A;  2B5I D;  4YWL A;  3LNL A;  1FHH A;  1IW7 D;  1TWA L;  1R9T L;  4POF A;  2NVY L;  1K83 L;  2Y0S P;  4QIW P;  1LKP A;  3GTP L;  5K2M E;  1NNQ A;  3S1Q L;  3K35 A;  1PFU A;  4A3B L;  3KYW A;  1VZI A;  5MFP A;  1BFY A;  6RXN A;  4AI0 A;  1RYT A;  1B2J A;  2JA7 L;  4TVM A;  4AHW A;  3MPS A;  2R93 L;  4Y7N L;  1Z92 B;  5EIN C;  1H7V A;  2HR5 A;  3SS2 A;  5GAD c;  7RXN A;  3I4M L;  4ZN3 B;  1BRF A;  2CKA A;  4BBS L;  5JVG 1;  3P8B A;  3K7A L;  5MGN A;  4E6Y A;  2J9U B;  3PIO 1;  3GTG L;  3HOU L;  1TWF L;  4V19 6;  4A93 L;  5GAG c;  3S2D L;  3PO2 L;  1IU6 A;  2PSM C;  2VL6 A;  3LWP B;  5DM7 1;  3WWL A;  1RB9 A;  2M6P A;  3QVD A;  4TPU A;  2M4V A;  2VUM L;  1T9O A;  2H12 A;  2R7Z L;  5C44 L;  2O5J D;  5M5W L;  1ODH A;  3HAX C;  3J7Y 1;  1RYQ A;  4GS7 D;  3LWR B; 
#chains in the Genus database with same CATH homology
 3S16 L;  3GTM L;  5C3E L;  4A3C L;  4BXX L;  1WCM L;  4A3M L;  3S14 L;  2JA6 L;  4A3K L;  1Y1W L;  5C4X L;  5FJ8 L;  3S1R L;  5M5Y L;  1TWA L;  1R9T L;  2JA5 L;  2NVY L;  4A3I L;  5M3M L;  4AYB P;  3HKZ P;  4C3I L;  1K83 L;  2Y0S P;  4QIW P;  1SFO L;  3GTP L;  3S1Q L;  4X6A L;  3HOY L;  3H0G L;  3S1N L;  3RZO L;  3CQZ L;  3S2H L;  4A3B L;  2WAQ P;  4A3G L;  4A3J L;  2B63 L;  2PMZ P;  1TWH L;  5M5X L;  5IYB L;  2JA7 L;  5C4J L;  2R93 L;  1TWC L;  3HOZ L;  5IYD L;  5IP9 L;  4Y7N L;  4C3J L;  4A3D L;  2E2H L;  5IYC L;  3S17 L;  4BY7 L;  4A3L L;  3I4M L;  4BBS L;  3PO3 L;  3M3Y L;  2R92 L;  2JA8 L;  4A3F L;  1Y1V L;  2WB1 P;  3M4O L;  3H3V M;  3K7A L;  5IP7 L;  3RZD L;  2E2I L;  2E2J L;  3GTG L;  3HOU L;  2YU9 L;  1TWF L;  4Y52 L;  4A93 L;  3S2D L;  3PO2 L;  2NVQ L;  4BBR L;  3GTL L;  1TWG L;  3S1M L;  3FKI L;  3I4N L;  1I6H L;  4C3H L;  3S15 L;  3HOX L;  2VUM L;  2R7Z L;  5C44 L;  3GTK L;  5M5W L;  4A3E L;  3HOW L;  5FLM L;  1I3Q L;  3GTJ L;  2NVT L;  3HOV L;  3GTO L;  3GTQ L;  5M3F L;  1I50 L;  4C2M 1;  2NVX L;  4BY1 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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