4C3HL

Structure of 14-subunit rna polymerase i at 3.27 a resolution, crystal form c2-93
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
45
structure length
45
Chain Sequence
TLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the 14-Subunit RNA Polymerase I
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA190
total genus 2
structure length 45
sequence length 45
ec nomenclature
pdb deposition date 2013-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4c3hL00
4AYBP 4A3IL 4X6AL 1TWFL 2R93L 1WCML 3S1RL 3S16L 1TWGL 5FJ8L 1Y1WL 3GTJL 3HKZP 2E2JL 3PO2L 1TWHL 3S1QL 4A3DL 3HOXL 3S15L 4C2M1 5IYCL 3I4NL 4A3LL 3S1NL 3FKIL 4QIWP 5IYDL 5FLML 1TWCL 4A3GL 3S2HL 4A3FL 3H3VM 2JA5L 3RZDL 5C3EL 4BBSL 4C3JL 5M5XL 1K83L 1SFOL 5M3ML 2VUML 3GTML 2YU9L 2NVYL 3K7AL 4Y7NL 4A93L 3GTOL 2Y0SP 5IP7L 4A3EL 1I50L 1I3QL 5IP9L 2JA7L 3M4OL 3S14L 3S1ML 3S17L 2E2IL 3RZOL 3GTKL 3M3YL 4A3CL 2WAQP 5C44L 2WB1P 2B63L 3HOWL 3GTPL 4Y52L 2NVTL 5C4XL 5M5WL 3HOVL 1R9TL 3I4ML 2NVQL 5M5YL 2JA8L 3HOUL 2E2HL 4C3IL 2PMZP 3HOYL 3H0GL 2JA6L 5M3FL 2R92L 3S2DL 3HOZL 4A3KL 4A3ML 3GTGL 3GTLL 2NVXL 4BBRL 4A3JL 1Y1VL 3CQZL 4BXXL 4BY1L 2R7ZL 3PO3L 1I6HL 1TWAL 5C4JL 5IYBL 3GTQL 4BY7L 4C3HL 4A3BL
chains in the Genus database with same CATH superfamily
5MGNA 4AYBP 1YUZA 4UY81 3LWVB 1LKMA 2R93L 1JYBA 3HJYB 3H99A 1R0HA 2XJVA 1YK5A 2ERJA 3MPSA 1S24A 1Y1WL 3GTJL 2E2JL 1SMWA 3KYYA 5IYCL 4QIWP 3RYGA 4XGHA 3H3VM 1YUXA 4YWMA 1R0GA 5C3EL 4C3JL 2PVEA 4A93L 2M6OA 2Y0SP 1B2JA 1RYQA 4LHNA 2JA7L 2K2DA 5DM71 1CADA 2XJTA 3S17L 2E2IL 4LHLA 3RZOL 1H7VA 2NYDA 1B13A 1IU5A 4GS7D 1PFYA 1OWCA 2B63L 2M4VA 3RZ6A 2RFKB 3H9CA 1NXEA 1SMUA 3A44A 1R9TL 3I4ML 2JI1A 1PFVA 4B8CD 4AR5A 1R0JA 4AR3A 5MFPA 2JA6L 3PL5A 3S2DL 2A6ED 1T9QA 1ZRPA 3KYVA 2O5JD 1SMMA 1RB9A 1Y1VL 4BY1L 3PO3L 3LWQB 5C4JL 4AI1A 4BY7L 4ME3A 3FDJA 1QYBA 4XXBB 4X6AL 2B5ID 1PZXA 3P8BA 2JI2A 3S16L 4AI2A 7RXNA 2A69D 2V0EA 1LTLA 3HOXL 3PIO1 4POFA 1F4LA 4A3LL 2PYAA 3S1NL 1TWCL 1R0IA 4A3GL 2XJUA 1NXGA 1Z92B 3RZDL 2C6BA 3PKJA 4BBSL 3LWOB 1K83L 4POGA 4TPUA 2NVYL 1P7PA 4Y7NL 2XJSA 5AI2A 5AN9H 2CKCA 1B2OA 3J7Z1 2LCQA 2WAQP 1S2ZA 1T9OA 2WB1P 2MS3A 2HVYC 5EINC 5DM61 5M5WL 3HOVL 2DSXA 2GMGA 4AI3A 1ODHA 2NVQL 5M5YL 3PZAA 3KYUA 1NNQA 4C3IL 4JAGA 5M3FL 1DVBA 2R92L 1LKOA 1PFUA 2NVXL 3H9BA 3CQZL 4BXXL 2KKDA 2H12A 2C6AA 1TWAL 1FHMA 3LWPB 2APOB 3GTQL 4E6YA 2A6HD 1TWFL 2Z3RB 3LPEB 4ZN1B 1YK4A 1TWGL 4AR6A 5FJ8L 1IRNA 5JVH1 4ZN3B 3HKZP 3IU3I 2RDVA 3PO2L 1TWHL 1QCVA 3S1QL 3S15L 3I4NL 3MSUA 3J7Y1 5AI3A 2KN9A 3LNLA 4A3FL 3PWFA 2JA5L 2PPTA 5RXNA 3QVDA 5M5XL 3K35A 1BE7A 1SFOL 3QQCE 4JADA 2VUML 3GTML 1VZHA 3K7AL 3GTOL 4A3EL 1I50L 1I3QL 2BE5D 5IP9L 3S14L 2HR5A 3WWNB 1S30A 3B08B 4A3CL 5IY0A 3HOWL 3GTPL 2NVTL 4TVMA 2Z3QB 2PSMC 6RXNA 2E2HL 3HOUL 3NFPI 4RXNA 2PMZP 1RYTA 4K9FA 1C09A 4A3ML 3VPBE 1DX8A 4JAEA 1LKPA 5H1Sc 2AQCA 3HJWB 3GTGL 3GTLL 5JVG1 3PKIA 2M4YA 5GAGc 5IYBL 2M6PA 1E8JA 4A3BL 4WFN1 1IROA 4A3IL 3KYXA 1WCML 2ZIXA 3S1RL 4AR4A 5MFZA 2CR8A 4A3DL 2VL6A 4C2M1 3JR7A 1IW7D 3FKIL 8RXNA 5IYDL 2CKAA 4AHXA 5FLML 1BFYA 3S2HL 2A68D 2J9UB 1QQTA 1T9PA 2EY4E 3LWRB 1PFWA 3RZTA 3B0AB 1VCXA 1OWBA 5MLC3 1CAAA 3P2AA 4AHZA 5M3ML 2V0FA 4AHYA 2JI3A 2YU9L 5IP7L 2QL0A 2PVXA 3SS2A 4V196 3MQKB 3M4OL 3S1ML 4U671 1RDGA 5K2ME 1YV1A 2XJPA 3GTKL 1IU6A 2ERSA 2V3BB 3ZG6A 1VZIA 3M3YL 1WJVA 4G6BA 1FHHA 5C44L 1BQ9A 5MF6A 5GADc 1BRFA 3KYWA 1RDVA 2XJRA 4Y52L 3PIP1 5C4XL 1B71A 2AUSB 1RWDA 1VZGA 2JA8L 4AHWA 3HOYL 1BQ8A 5EIOC 3H0GL 5GAHc 4AI0A 4JAFA 3HOZL 4A3KL 2L0ZA 4BBRL 4A3JL 3HAXC 3WWLA 3H97A 2R7ZL 4YWLA 1I6HL 2XJQA 1R0FA 5GAEc 2AYJA 4C3HL
chains in the Genus database with same CATH topology
4AYBP 4A3IL 4X6AL 1TWFL 2R93L 1WCML 3S1RL 3S16L 1TWGL 5FJ8L 1Y1WL 3GTJL 3HKZP 2E2JL 3PO2L 1TWHL 3S1QL 4A3DL 3HOXL 3S15L 4C2M1 5IYCL 3I4NL 4A3LL 3S1NL 3FKIL 4QIWP 5IYDL 5FLML 1TWCL 4A3GL 3S2HL 4A3FL 3H3VM 2JA5L 3RZDL 5C3EL 4BBSL 4C3JL 5M5XL 1K83L 1SFOL 5M3ML 2VUML 3GTML 2YU9L 2NVYL 3K7AL 4Y7NL 4A93L 3GTOL 2Y0SP 5IP7L 4A3EL 1I50L 1I3QL 5IP9L 2JA7L 3M4OL 3S14L 3S1ML 3S17L 2E2IL 3RZOL 3GTKL 3M3YL 4A3CL 2WAQP 5C44L 2WB1P 2B63L 3HOWL 3GTPL 4Y52L 2NVTL 5C4XL 5M5WL 3HOVL 1R9TL 3I4ML 2NVQL 5M5YL 2JA8L 3HOUL 2E2HL 4C3IL 2PMZP 3HOYL 3H0GL 2JA6L 5M3FL 2R92L 3S2DL 3HOZL 4A3KL 4A3ML 3GTGL 3GTLL 2NVXL 4BBRL 4A3JL 1Y1VL 3CQZL 4BXXL 4BY1L 2R7ZL 3PO3L 1I6HL 1TWAL 5C4JL 5IYBL 3GTQL 4BY7L 4C3HL 4A3BL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AYB P;  4A3I L;  4X6A L;  1TWF L;  2R93 L;  1WCM L;  3S1R L;  3S16 L;  1TWG L;  5FJ8 L;  1Y1W L;  3GTJ L;  3HKZ P;  2E2J L;  3PO2 L;  1TWH L;  3S1Q L;  4A3D L;  3HOX L;  3S15 L;  4C2M 1;  5IYC L;  3I4N L;  4A3L L;  3S1N L;  3FKI L;  4QIW P;  5IYD L;  5FLM L;  1TWC L;  4A3G L;  3S2H L;  4A3F L;  3H3V M;  2JA5 L;  3RZD L;  5C3E L;  4BBS L;  4C3J L;  5M5X L;  1K83 L;  1SFO L;  5M3M L;  2VUM L;  3GTM L;  2YU9 L;  2NVY L;  3K7A L;  4Y7N L;  4A93 L;  3GTO L;  2Y0S P;  5IP7 L;  4A3E L;  1I50 L;  1I3Q L;  5IP9 L;  2JA7 L;  3M4O L;  3S14 L;  3S1M L;  3S17 L;  2E2I L;  3RZO L;  3GTK L;  3M3Y L;  4A3C L;  2WAQ P;  5C44 L;  2WB1 P;  2B63 L;  3HOW L;  3GTP L;  4Y52 L;  2NVT L;  5C4X L;  5M5W L;  3HOV L;  1R9T L;  3I4M L;  2NVQ L;  5M5Y L;  2JA8 L;  3HOU L;  2E2H L;  4C3I L;  2PMZ P;  3HOY L;  3H0G L;  2JA6 L;  5M3F L;  2R92 L;  3S2D L;  3HOZ L;  4A3K L;  4A3M L;  3GTG L;  3GTL L;  2NVX L;  4BBR L;  4A3J L;  1Y1V L;  3CQZ L;  4BXX L;  4BY1 L;  2R7Z L;  3PO3 L;  1I6H L;  1TWA L;  5C4J L;  5IYB L;  3GTQ L;  4BY7 L;  4C3H L;  4A3B L; 
#chains in the Genus database with same CATH topology
 5MGN A;  4AYB P;  1YUZ A;  4UY8 1;  3LWV B;  1LKM A;  2R93 L;  1JYB A;  3HJY B;  3H99 A;  1R0H A;  2XJV A;  1YK5 A;  2ERJ A;  3MPS A;  1S24 A;  1Y1W L;  3GTJ L;  2E2J L;  1SMW A;  3KYY A;  5IYC L;  4QIW P;  3RYG A;  4XGH A;  3H3V M;  1YUX A;  4YWM A;  1R0G A;  5C3E L;  4C3J L;  2PVE A;  4A93 L;  2M6O A;  2Y0S P;  1B2J A;  1RYQ A;  4LHN A;  2JA7 L;  2K2D A;  5DM7 1;  1CAD A;  2XJT A;  3S17 L;  2E2I L;  4LHL A;  3RZO L;  1H7V A;  2NYD A;  1B13 A;  1IU5 A;  4GS7 D;  1PFY A;  1OWC A;  2B63 L;  2M4V A;  3RZ6 A;  2RFK B;  3H9C A;  1NXE A;  1SMU A;  3A44 A;  1R9T L;  3I4M L;  2JI1 A;  1PFV A;  4B8C D;  4AR5 A;  1R0J A;  4AR3 A;  5MFP A;  2JA6 L;  3PL5 A;  3S2D L;  2A6E D;  1T9Q A;  1ZRP A;  3KYV A;  2O5J D;  1SMM A;  1RB9 A;  1Y1V L;  4BY1 L;  3PO3 L;  3LWQ B;  5C4J L;  4AI1 A;  4BY7 L;  4ME3 A;  3FDJ A;  1QYB A;  4XXB B;  4X6A L;  2B5I D;  1PZX A;  3P8B A;  2JI2 A;  3S16 L;  4AI2 A;  7RXN A;  2A69 D;  2V0E A;  1LTL A;  3HOX L;  3PIO 1;  4POF A;  1F4L A;  4A3L L;  2PYA A;  3S1N L;  1TWC L;  1R0I A;  4A3G L;  2XJU A;  1NXG A;  1Z92 B;  3RZD L;  2C6B A;  3PKJ A;  4BBS L;  3LWO B;  1K83 L;  4POG A;  4TPU A;  2NVY L;  1P7P A;  4Y7N L;  2XJS A;  5AI2 A;  5AN9 H;  2CKC A;  1B2O A;  3J7Z 1;  2LCQ A;  2WAQ P;  1S2Z A;  1T9O A;  2WB1 P;  2MS3 A;  2HVY C;  5EIN C;  5DM6 1;  5M5W L;  3HOV L;  2DSX A;  2GMG A;  4AI3 A;  1ODH A;  2NVQ L;  5M5Y L;  3PZA A;  3KYU A;  1NNQ A;  4C3I L;  4JAG A;  5M3F L;  1DVB A;  2R92 L;  1LKO A;  1PFU A;  2NVX L;  3H9B A;  3CQZ L;  4BXX L;  2KKD A;  2H12 A;  2C6A A;  1TWA L;  1FHM A;  3LWP B;  2APO B;  3GTQ L;  4E6Y A;  2A6H D;  1TWF L;  2Z3R B;  3LPE B;  4ZN1 B;  1YK4 A;  1TWG L;  4AR6 A;  5FJ8 L;  1IRN A;  5JVH 1;  4ZN3 B;  3HKZ P;  3IU3 I;  2RDV A;  3PO2 L;  1TWH L;  1QCV A;  3S1Q L;  3S15 L;  3I4N L;  3MSU A;  3J7Y 1;  5AI3 A;  2KN9 A;  3LNL A;  4A3F L;  3PWF A;  2JA5 L;  2PPT A;  5RXN A;  3QVD A;  5M5X L;  3K35 A;  1BE7 A;  1SFO L;  3QQC E;  4JAD A;  2VUM L;  3GTM L;  1VZH A;  3K7A L;  3GTO L;  4A3E L;  1I50 L;  1I3Q L;  2BE5 D;  5IP9 L;  3S14 L;  2HR5 A;  3WWN B;  1S30 A;  3B08 B;  4A3C L;  5IY0 A;  3HOW L;  3GTP L;  2NVT L;  4TVM A;  2Z3Q B;  2PSM C;  6RXN A;  2E2H L;  3HOU L;  3NFP I;  4RXN A;  2PMZ P;  1RYT A;  4K9F A;  1C09 A;  4A3M L;  3VPB E;  1DX8 A;  4JAE A;  1LKP A;  5H1S c;  2AQC A;  3HJW B;  3GTG L;  3GTL L;  5JVG 1;  3PKI A;  2M4Y A;  5GAG c;  5IYB L;  2M6P A;  1E8J A;  4A3B L;  4WFN 1;  1IRO A;  4A3I L;  3KYX A;  1WCM L;  2ZIX A;  3S1R L;  4AR4 A;  5MFZ A;  2CR8 A;  4A3D L;  2VL6 A;  4C2M 1;  3JR7 A;  1IW7 D;  3FKI L;  8RXN A;  5IYD L;  2CKA A;  4AHX A;  5FLM L;  1BFY A;  3S2H L;  2A68 D;  2J9U B;  1QQT A;  1T9P A;  2EY4 E;  3LWR B;  1PFW A;  3RZT A;  3B0A B;  1VCX A;  1OWB A;  5MLC 3;  1CAA A;  3P2A A;  4AHZ A;  5M3M L;  2V0F A;  4AHY A;  2JI3 A;  2YU9 L;  5IP7 L;  2QL0 A;  2PVX A;  3SS2 A;  4V19 6;  3MQK B;  3M4O L;  3S1M L;  4U67 1;  1RDG A;  5K2M E;  1YV1 A;  2XJP A;  3GTK L;  1IU6 A;  2ERS A;  2V3B B;  3ZG6 A;  1VZI A;  3M3Y L;  1WJV A;  4G6B A;  1FHH A;  5C44 L;  1BQ9 A;  5MF6 A;  5GAD c;  1BRF A;  3KYW A;  1RDV A;  2XJR A;  4Y52 L;  3PIP 1;  5C4X L;  1B71 A;  2AUS B;  1RWD A;  1VZG A;  2JA8 L;  4AHW A;  3HOY L;  1BQ8 A;  5EIO C;  3H0G L;  5GAH c;  4AI0 A;  4JAF A;  3HOZ L;  4A3K L;  2L0Z A;  4BBR L;  4A3J L;  3HAX C;  3WWL A;  3H97 A;  2R7Z L;  4YWL A;  1I6H L;  2XJQ A;  1R0F A;  5GAE c;  2AYJ A;  4C3H L; 
#chains in the Genus database with same CATH homology
 4AYB P;  4A3I L;  4X6A L;  1TWF L;  2R93 L;  1WCM L;  3S1R L;  3S16 L;  1TWG L;  5FJ8 L;  1Y1W L;  3GTJ L;  3HKZ P;  2E2J L;  3PO2 L;  1TWH L;  3S1Q L;  4A3D L;  3HOX L;  3S15 L;  4C2M 1;  5IYC L;  3I4N L;  4A3L L;  3S1N L;  3FKI L;  4QIW P;  5IYD L;  5FLM L;  1TWC L;  4A3G L;  3S2H L;  4A3F L;  3H3V M;  2JA5 L;  3RZD L;  5C3E L;  4BBS L;  4C3J L;  5M5X L;  1K83 L;  1SFO L;  5M3M L;  2VUM L;  3GTM L;  2YU9 L;  2NVY L;  3K7A L;  4Y7N L;  4A93 L;  3GTO L;  2Y0S P;  5IP7 L;  4A3E L;  1I50 L;  1I3Q L;  5IP9 L;  2JA7 L;  3M4O L;  3S14 L;  3S1M L;  3S17 L;  2E2I L;  3RZO L;  3GTK L;  3M3Y L;  4A3C L;  2WAQ P;  5C44 L;  2WB1 P;  2B63 L;  3HOW L;  3GTP L;  4Y52 L;  2NVT L;  5C4X L;  5M5W L;  3HOV L;  1R9T L;  3I4M L;  2NVQ L;  5M5Y L;  2JA8 L;  3HOU L;  2E2H L;  4C3I L;  2PMZ P;  3HOY L;  3H0G L;  2JA6 L;  5M3F L;  2R92 L;  3S2D L;  3HOZ L;  4A3K L;  4A3M L;  3GTG L;  3GTL L;  2NVX L;  4BBR L;  4A3J L;  1Y1V L;  3CQZ L;  4BXX L;  4BY1 L;  2R7Z L;  3PO3 L;  1I6H L;  1TWA L;  5C4J L;  5IYB L;  3GTQ L;  4BY7 L;  4C3H L;  4A3B L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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