4C3JL

Structure of 14-subunit rna polymerase i at 3.35 a resolution, crystal form c2-90
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
45
structure length
45
Chain Sequence
TLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the 14-Subunit RNA Polymerase I
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA190
total genus 2
structure length 45
sequence length 45
ec nomenclature
pdb deposition date 2013-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4c3jL00
4A3CL 3K7AL 5IYDL 3S1RL 2E2HL 3GTML 2R7ZL 4C3IL 1SFOL 2R93L 3CQZL 4BBSL 5M3FL 4QIWP 5M5YL 4Y7NL 4A3JL 5M3ML 2Y0SP 4AYBP 4A3EL 3S2DL 5IP7L 3S1QL 3I4NL 1I3QL 1I6HL 4A3BL 2R92L 4C3JL 5C44L 1TWAL 3H3VM 4BXXL 4A3FL 2PMZP 5FJ8L 1R9TL 1TWFL 2B63L 4A93L 5C4JL 2NVQL 1TWGL 4BY7L 3HOXL 2VUML 4A3ML 3HOWL 3RZOL 5FLML 5M5WL 4A3KL 4A3GL 3HOZL 3S2HL 2E2JL 3S17L 2E2IL 3S1ML 1Y1VL 5IP9L 1TWHL 3HOYL 1Y1WL 2NVXL 3S14L 2WAQP 2JA6L 4BY1L 1I50L 4A3IL 3GTQL 1WCML 3M4OL 3HOUL 3RZDL 3PO2L 5C4XL 3HKZP 3S1NL 2NVTL 2YU9L 4C2M1 3GTLL 3S16L 3GTGL 3HOVL 3I4ML 1K83L 4A3DL 5IYBL 3GTOL 5M5XL 2JA5L 3H0GL 3GTKL 3GTPL 2WB1P 2NVYL 4X6AL 3PO3L 4BBRL 2JA7L 5IYCL 3FKIL 1TWCL 3S15L 3GTJL 4A3LL 4Y52L 3M3YL 4C3HL 5C3EL 2JA8L
chains in the Genus database with same CATH superfamily
2LCQA 4AR6A 5IYDL 3J7Y1 3QQCE 2R7ZL 1LTLA 4XGHA 3H97A 1IRNA 4QIWP 3KYWA 5AI3A 2A6HD 2Y0SP 2CKAA 1P7PA 1RYTA 1T9PA 2JI3A 1I6HL 4JAEA 4A3BL 1RB9A 5AI2A 1PZXA 4C3JL 1PFVA 1TWAL 4A3FL 8RXNA 2PMZP 4A93L 2B63L 2JI2A 2PVEA 2RFKB 1PFWA 4AR5A 3PWFA 3RZOL 5MFZA 1R0IA 4A3GL 1BFYA 2E2JL 3LWQB 3PKIA 3S17L 1Y1VL 5IP9L 1QCVA 4AHXA 4YWMA 3PKJA 3KYXA 2RDVA 3K35A 2JA6L 4BY1L 2A6ED 4A3IL 1SMMA 3M4OL 2PYAA 4LHNA 5RXNA 4AI1A 2JI1A 1LKPA 3P8BA 3B08B 2XJPA 3HJWB 2PVXA 3ZG6A 3GTGL 1H7VA 1B71A 3WWNB 1BRFA 1VCXA 1BE7A 3GTOL 1SMWA 1QQTA 1F4LA 3H0GL 2NYDA 4U671 3GTKL 2C6AA 2WB1P 5JVG1 4AR3A 3MPSA 3GTPL 5IYCL 3KYUA 3PIP1 5C3EL 3B0AB 3K7AL 2E2HL 3A44A 3GTML 3H9BA 4BBSL 1Z92B 1PFUA 4Y7NL 1DVBA 4AYBP 4AR4A 2L0ZA 4A3EL 3J7Z1 2KKDA 2AYJA 1R0FA 1OWBA 1CAAA 1B2OA 2R92L 2M6OA 5C44L 5MLC3 4V196 5C4JL 4ME3A 1BQ9A 5GAEc 2NVQL 3HOXL 2K2DA 2VUML 4A3ML 3MQKB 4UY81 4AI3A 5FLML 3RYGA 3QVDA 3S1ML 1IROA 1FHMA 2NVXL 2B5ID 2VL6A 2XJRA 3S14L 1IU6A 1R0JA 4POFA 1WCML 3HOUL 2DSXA 3RZDL 5EINC 1FHHA 2AUSB 4AI2A 2M6PA 3I4ML 3LWRB 4GS7D 2QL0A 5K2ME 1RYQA 5DM71 4X6AL 3PO3L 3LWOB 2JA7L 1VZGA 1YUXA 3FKIL 1TWCL 3GTJL 2CR8A 3HOYL 2CKCA 3S1RL 4AI0A 3KYVA 4POGA 2V3BB 4C3IL 1SFOL 2PPTA 2H12A 2R93L 5H1Sc 2GMGA 4ZN3B 5M3FL 5MFPA 3VPBE 4E6YA 3S1QL 3LWVB 3HAXC 1CADA 1VZIA 4JAFA 3H3VM 1BQ8A 4BXXL 3WWLA 3PL5A 1JYBA 1YV1A 1R0HA 2ERSA 1TWGL 4BY7L 1QYBA 3HOWL 5MGNA 5M5WL 3HOZL 3HJYB 2XJUA 3SS2A 3KYYA 2J9UB 1Y1WL 2A69D 5DM61 2WAQP 1ODHA 3GTQL 2Z3RB 3PO2L 5GAHc 1R0GA 5C4XL 1VZHA 3HKZP 2C6BA 3MSUA 5AN9H 3S1NL 4K9FA 2EY4E 4C2M1 1E8JA 4B8CD 2A68D 2XJSA 1NNQA 2JA5L 4TVMA 2HR5A 3FDJA 1T9QA 1NXEA 2Z3QB 1WJVA 3NFPI 3IU3I 3S15L 1NXGA 2MS3A 2KN9A 3PZAA 4Y52L 2XJTA 1S2ZA 1LKOA 4A3CL 1S24A 4LHLA 2O5JD 3JR7A 2V0EA 5GAGc 1IU5A 1PFYA 3CQZL 1RDVA 5M5YL 1OWCA 2V0FA 4A3JL 5M3ML 3P2AA 3S2DL 5IP7L 2APOB 5EIOC 3I4NL 1I3QL 3LPEB 6RXNA 2AQCA 1SMUA 4JADA 1B13A 5FJ8L 1R9TL 1TWFL 2ERJA 1DX8A 1RDGA 4XXBB 3RZTA 1RWDA 5IY0A 4A3KL 3S2HL 2E2IL 4AHZA 1TWHL 3RZ6A 3LNLA 1LKMA 7RXNA 1YK5A 4RXNA 2ZIXA 5MF6A 1I50L 3LWPB 2PSMC 2XJVA 3PIO1 2NVTL 2YU9L 4AHYA 3GTLL 4WFN1 1C09A 5JVH1 3S16L 1YUZA 4JAGA 4TPUA 3HOVL 2HVYC 1K83L 4ZN1B 3H9CA 3H99A 4A3DL 1YK4A 1IW7D 1T9OA 5IYBL 2M4YA 2BE5D 4AHWA 1B2JA 5M5XL 4G6BA 2NVYL 5GADc 2M4VA 4BBRL 4YWLA 2XJQA 1ZRPA 4A3LL 1S30A 3M3YL 4C3HL 2JA8L
chains in the Genus database with same CATH topology
4A3CL 3K7AL 5IYDL 3S1RL 2E2HL 3GTML 2R7ZL 4C3IL 1SFOL 2R93L 3CQZL 4BBSL 5M3FL 4QIWP 5M5YL 4Y7NL 4A3JL 5M3ML 2Y0SP 4AYBP 4A3EL 3S2DL 5IP7L 3S1QL 3I4NL 1I3QL 1I6HL 4A3BL 2R92L 4C3JL 5C44L 1TWAL 3H3VM 4BXXL 4A3FL 2PMZP 5FJ8L 1R9TL 1TWFL 2B63L 4A93L 5C4JL 2NVQL 1TWGL 4BY7L 3HOXL 2VUML 4A3ML 3HOWL 3RZOL 5FLML 5M5WL 4A3KL 4A3GL 3HOZL 3S2HL 2E2JL 3S17L 2E2IL 3S1ML 1Y1VL 5IP9L 1TWHL 3HOYL 1Y1WL 2NVXL 3S14L 2WAQP 2JA6L 4BY1L 1I50L 4A3IL 3GTQL 1WCML 3M4OL 3HOUL 3RZDL 3PO2L 5C4XL 3HKZP 3S1NL 2NVTL 2YU9L 4C2M1 3GTLL 3S16L 3GTGL 3HOVL 3I4ML 1K83L 4A3DL 5IYBL 3GTOL 5M5XL 2JA5L 3H0GL 3GTKL 3GTPL 2WB1P 2NVYL 4X6AL 3PO3L 4BBRL 2JA7L 5IYCL 3FKIL 1TWCL 3S15L 3GTJL 4A3LL 4Y52L 3M3YL 4C3HL 5C3EL 2JA8L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3C L;  3K7A L;  5IYD L;  3S1R L;  2E2H L;  3GTM L;  2R7Z L;  4C3I L;  1SFO L;  2R93 L;  3CQZ L;  4BBS L;  5M3F L;  4QIW P;  5M5Y L;  4Y7N L;  4A3J L;  5M3M L;  2Y0S P;  4AYB P;  4A3E L;  3S2D L;  5IP7 L;  3S1Q L;  3I4N L;  1I3Q L;  1I6H L;  4A3B L;  2R92 L;  4C3J L;  5C44 L;  1TWA L;  3H3V M;  4BXX L;  4A3F L;  2PMZ P;  5FJ8 L;  1R9T L;  1TWF L;  2B63 L;  4A93 L;  5C4J L;  2NVQ L;  1TWG L;  4BY7 L;  3HOX L;  2VUM L;  4A3M L;  3HOW L;  3RZO L;  5FLM L;  5M5W L;  4A3K L;  4A3G L;  3HOZ L;  3S2H L;  2E2J L;  3S17 L;  2E2I L;  3S1M L;  1Y1V L;  5IP9 L;  1TWH L;  3HOY L;  1Y1W L;  2NVX L;  3S14 L;  2WAQ P;  2JA6 L;  4BY1 L;  1I50 L;  4A3I L;  3GTQ L;  1WCM L;  3M4O L;  3HOU L;  3RZD L;  3PO2 L;  5C4X L;  3HKZ P;  3S1N L;  2NVT L;  2YU9 L;  4C2M 1;  3GTL L;  3S16 L;  3GTG L;  3HOV L;  3I4M L;  1K83 L;  4A3D L;  5IYB L;  3GTO L;  5M5X L;  2JA5 L;  3H0G L;  3GTK L;  3GTP L;  2WB1 P;  2NVY L;  4X6A L;  3PO3 L;  4BBR L;  2JA7 L;  5IYC L;  3FKI L;  1TWC L;  3S15 L;  3GTJ L;  4A3L L;  4Y52 L;  3M3Y L;  4C3H L;  5C3E L;  2JA8 L; 
#chains in the Genus database with same CATH topology
 2LCQ A;  4AR6 A;  5IYD L;  3J7Y 1;  3QQC E;  2R7Z L;  1LTL A;  4XGH A;  3H97 A;  1IRN A;  4QIW P;  3KYW A;  5AI3 A;  2A6H D;  2Y0S P;  2CKA A;  1P7P A;  1RYT A;  1T9P A;  2JI3 A;  1I6H L;  4JAE A;  4A3B L;  1RB9 A;  5AI2 A;  1PZX A;  4C3J L;  1PFV A;  1TWA L;  4A3F L;  8RXN A;  2PMZ P;  4A93 L;  2B63 L;  2JI2 A;  2PVE A;  2RFK B;  1PFW A;  4AR5 A;  3PWF A;  3RZO L;  5MFZ A;  1R0I A;  4A3G L;  1BFY A;  2E2J L;  3LWQ B;  3PKI A;  3S17 L;  1Y1V L;  5IP9 L;  1QCV A;  4AHX A;  4YWM A;  3PKJ A;  3KYX A;  2RDV A;  3K35 A;  2JA6 L;  4BY1 L;  2A6E D;  4A3I L;  1SMM A;  3M4O L;  2PYA A;  4LHN A;  5RXN A;  4AI1 A;  2JI1 A;  1LKP A;  3P8B A;  3B08 B;  2XJP A;  3HJW B;  2PVX A;  3ZG6 A;  3GTG L;  1H7V A;  1B71 A;  3WWN B;  1BRF A;  1VCX A;  1BE7 A;  3GTO L;  1SMW A;  1QQT A;  1F4L A;  3H0G L;  2NYD A;  4U67 1;  3GTK L;  2C6A A;  2WB1 P;  5JVG 1;  4AR3 A;  3MPS A;  3GTP L;  5IYC L;  3KYU A;  3PIP 1;  5C3E L;  3B0A B;  3K7A L;  2E2H L;  3A44 A;  3GTM L;  3H9B A;  4BBS L;  1Z92 B;  1PFU A;  4Y7N L;  1DVB A;  4AYB P;  4AR4 A;  2L0Z A;  4A3E L;  3J7Z 1;  2KKD A;  2AYJ A;  1R0F A;  1OWB A;  1CAA A;  1B2O A;  2R92 L;  2M6O A;  5C44 L;  5MLC 3;  4V19 6;  5C4J L;  4ME3 A;  1BQ9 A;  5GAE c;  2NVQ L;  3HOX L;  2K2D A;  2VUM L;  4A3M L;  3MQK B;  4UY8 1;  4AI3 A;  5FLM L;  3RYG A;  3QVD A;  3S1M L;  1IRO A;  1FHM A;  2NVX L;  2B5I D;  2VL6 A;  2XJR A;  3S14 L;  1IU6 A;  1R0J A;  4POF A;  1WCM L;  3HOU L;  2DSX A;  3RZD L;  5EIN C;  1FHH A;  2AUS B;  4AI2 A;  2M6P A;  3I4M L;  3LWR B;  4GS7 D;  2QL0 A;  5K2M E;  1RYQ A;  5DM7 1;  4X6A L;  3PO3 L;  3LWO B;  2JA7 L;  1VZG A;  1YUX A;  3FKI L;  1TWC L;  3GTJ L;  2CR8 A;  3HOY L;  2CKC A;  3S1R L;  4AI0 A;  3KYV A;  4POG A;  2V3B B;  4C3I L;  1SFO L;  2PPT A;  2H12 A;  2R93 L;  5H1S c;  2GMG A;  4ZN3 B;  5M3F L;  5MFP A;  3VPB E;  4E6Y A;  3S1Q L;  3LWV B;  3HAX C;  1CAD A;  1VZI A;  4JAF A;  3H3V M;  1BQ8 A;  4BXX L;  3WWL A;  3PL5 A;  1JYB A;  1YV1 A;  1R0H A;  2ERS A;  1TWG L;  4BY7 L;  1QYB A;  3HOW L;  5MGN A;  5M5W L;  3HOZ L;  3HJY B;  2XJU A;  3SS2 A;  3KYY A;  2J9U B;  1Y1W L;  2A69 D;  5DM6 1;  2WAQ P;  1ODH A;  3GTQ L;  2Z3R B;  3PO2 L;  5GAH c;  1R0G A;  5C4X L;  1VZH A;  3HKZ P;  2C6B A;  3MSU A;  5AN9 H;  3S1N L;  4K9F A;  2EY4 E;  4C2M 1;  1E8J A;  4B8C D;  2A68 D;  2XJS A;  1NNQ A;  2JA5 L;  4TVM A;  2HR5 A;  3FDJ A;  1T9Q A;  1NXE A;  2Z3Q B;  1WJV A;  3NFP I;  3IU3 I;  3S15 L;  1NXG A;  2MS3 A;  2KN9 A;  3PZA A;  4Y52 L;  2XJT A;  1S2Z A;  1LKO A;  4A3C L;  1S24 A;  4LHL A;  2O5J D;  3JR7 A;  2V0E A;  5GAG c;  1IU5 A;  1PFY A;  3CQZ L;  1RDV A;  5M5Y L;  1OWC A;  2V0F A;  4A3J L;  5M3M L;  3P2A A;  3S2D L;  5IP7 L;  2APO B;  5EIO C;  3I4N L;  1I3Q L;  3LPE B;  6RXN A;  2AQC A;  1SMU A;  4JAD A;  1B13 A;  5FJ8 L;  1R9T L;  1TWF L;  2ERJ A;  1DX8 A;  1RDG A;  4XXB B;  3RZT A;  1RWD A;  5IY0 A;  4A3K L;  3S2H L;  2E2I L;  4AHZ A;  1TWH L;  3RZ6 A;  3LNL A;  1LKM A;  7RXN A;  1YK5 A;  4RXN A;  2ZIX A;  5MF6 A;  1I50 L;  3LWP B;  2PSM C;  2XJV A;  3PIO 1;  2NVT L;  2YU9 L;  4AHY A;  3GTL L;  4WFN 1;  1C09 A;  5JVH 1;  3S16 L;  1YUZ A;  4JAG A;  4TPU A;  3HOV L;  2HVY C;  1K83 L;  4ZN1 B;  3H9C A;  3H99 A;  4A3D L;  1YK4 A;  1IW7 D;  1T9O A;  5IYB L;  2M4Y A;  2BE5 D;  4AHW A;  1B2J A;  5M5X L;  4G6B A;  2NVY L;  5GAD c;  2M4V A;  4BBR L;  4YWL A;  2XJQ A;  1ZRP A;  4A3L L;  1S30 A;  3M3Y L;  4C3H L;  2JA8 L; 
#chains in the Genus database with same CATH homology
 4A3C L;  3K7A L;  5IYD L;  3S1R L;  2E2H L;  3GTM L;  2R7Z L;  4C3I L;  1SFO L;  2R93 L;  3CQZ L;  4BBS L;  5M3F L;  4QIW P;  5M5Y L;  4Y7N L;  4A3J L;  5M3M L;  2Y0S P;  4AYB P;  4A3E L;  3S2D L;  5IP7 L;  3S1Q L;  3I4N L;  1I3Q L;  1I6H L;  4A3B L;  2R92 L;  4C3J L;  5C44 L;  1TWA L;  3H3V M;  4BXX L;  4A3F L;  2PMZ P;  5FJ8 L;  1R9T L;  1TWF L;  2B63 L;  4A93 L;  5C4J L;  2NVQ L;  1TWG L;  4BY7 L;  3HOX L;  2VUM L;  4A3M L;  3HOW L;  3RZO L;  5FLM L;  5M5W L;  4A3K L;  4A3G L;  3HOZ L;  3S2H L;  2E2J L;  3S17 L;  2E2I L;  3S1M L;  1Y1V L;  5IP9 L;  1TWH L;  3HOY L;  1Y1W L;  2NVX L;  3S14 L;  2WAQ P;  2JA6 L;  4BY1 L;  1I50 L;  4A3I L;  3GTQ L;  1WCM L;  3M4O L;  3HOU L;  3RZD L;  3PO2 L;  5C4X L;  3HKZ P;  3S1N L;  2NVT L;  2YU9 L;  4C2M 1;  3GTL L;  3S16 L;  3GTG L;  3HOV L;  3I4M L;  1K83 L;  4A3D L;  5IYB L;  3GTO L;  5M5X L;  2JA5 L;  3H0G L;  3GTK L;  3GTP L;  2WB1 P;  2NVY L;  4X6A L;  3PO3 L;  4BBR L;  2JA7 L;  5IYC L;  3FKI L;  1TWC L;  3S15 L;  3GTJ L;  4A3L L;  4Y52 L;  3M3Y L;  4C3H L;  5C3E L;  2JA8 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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