4UT2A

X-ray structure of the human pp1 gamma catalytic subunit treated with ascorbate
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
294
structure length
291
Chain Sequence
KLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHEASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYGEFDNAGAMMSVDETLMSFQILKPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeted Redox Inhibition of Protein Phosphatase 1 by Nox4 Regulates Eif2Alpha-Mediated Stress Signaling.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUB
total genus 107
structure length 291
sequence length 294
chains with identical sequence B
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2014-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 4ut2A00
4IL1A 4V0WA 3QFMA 2A22A 2IAEC 1U32A 3THOB 4O43A 5HPEA 1OIDA 3QG5C 5EQVA 5J28A 4NZVA 2IE4C 1MF8A 3IB8A 3DSDA 1JK7A 4H1SA 3PSOA 3E7AA 4UT3B 1T71A 4HD0A 3IB7A 3EGGA 3GVEA 3RL4A 4FCXA 4FBWA 5F3WA 2O8GA 3PSNA 3N5UA 3H64A 3RL5A 4KKZA 1OIEA 3H68A 4UWQA 1S70A 1HPUA 4IYPC 4DHLA 5JPFA 5JPEA 4H2BA 3H63A 4ZX2A 3E7BA 2NYMC 2QFPA 3H69A 3KBPA 1FJMA 1SU1A 2AHDA 5JJTA 5IOHA 1UF3A 3H60A 3DW8C 2WDEA 4LTYA 3QFKA 3IVDA 3LL8A 5INBA 2USHA 2CV9A 2HYOA 3QFOA 4FBQA 1WAO1 2WDCA 4Q7FA 3TGHA 4O4KA 3CK2A 5B8IA 3T1IA 5DNYA 2QFRA 4B2OA 2KKNA 5C1VA 2Z72A 1S8EA 1NNWA 1HO5A 4JA7A 3H67A 2JOGA 1UTEA 4ORAA 3AV0A 4O24A 2ZBMA 2DFJA 4LU9A 1AUIA 2GJUA 2R17A 3JYFA 4ORCA 4DT2A 1QHWA 1M63A 3THNA 3DSCA 1XZWA 3K7WC 4F0ZA 4TUIA 1G5BA 1OI8A 2XMOA 3K7VC 1II7A 1HP1A 4LACC 4H2GA 2QJCA 3H62B 2NPPC 4KBPA 2BDXA 1S95A 1S3MA 3EGHA 4ORBA 4UT2A 3ZTVA 3V4YA 1S3NA 4I5LC 4J6OA 2NYLC 4TUGA 2BQ8X 1USHA 3C9FA 4H2FA 4MOYA 4OR9A 4G9JA 4ZVZA 4I5NC 3IVEA 3ZU0A 3HVQA 4V0XA 4MOVA 1IT6A 4XPNA 4H1YP 1Z2XA 4DSYA 3AUZA 1XM7A 2HY1A 2P6BA 1KBPA 3RQZA 4YKEA 4UT3A 1W24A 4M0VA 4FBKA 2WDFA 2Z1AA 1TCOA 2IE3C 2BCDA 4V0VA 2WDDA 3H66A 4MP0A 5GTUA 4WWLA 4JA9A 1S3LA 1T70A 3QFNA 3FGAC 1V73A 3RL3A 4O5GA 3P71C 3C5WC 3H61A 2HYPA 2Z06A 2Q8UA 3ICFA 1QFCA 1WARA 2YVTA 4H2IA 1Z2WA 2O8AA 2NXFA
chains in the Genus database with same CATH superfamily
4IL1A 4V0WA 3QFMA 2A22A 2IAEC 1U32A 3THOB 4O43A 5HPEA 1OIDA 3QG5C 5EQVA 5J28A 4NZVA 2IE4C 1MF8A 3IB8A 3DSDA 1JK7A 4H1SA 3PSOA 3E7AA 4UT3B 1T71A 4HD0A 3IB7A 3EGGA 2DXNA 3GVEA 3RL4A 4FCXA 4FBWA 5F3WA 2O8GA 3PSNA 3N5UA 3H64A 3RL5A 3D03A 4KKZA 1OIEA 3H68A 4UWQA 1S70A 1HPUA 4IYPC 4DHLA 5JPFA 5JPEA 4H2BA 3H63A 4ZX2A 3E7BA 2NYMC 2QFPA 3H69A 3KBPA 1FJMA 1SU1A 2AHDA 2YEQA 5JJTA 5IOHA 1UF3A 3H60A 3DW8C 2WDEA 4LTYA 3QFKA 3IVDA 3LL8A 5INBA 2USHA 2CV9A 2HYOA 3QFOA 4FBQA 3FLOA 1WAO1 2WDCA 4Q7FA 3TGHA 4O4KA 3CK2A 5B8IA 3T1IA 5DNYA 2QFRA 4B2OA 2KKNA 5C1VA 2Z72A 1S8EA 1NNWA 1HO5A 4JA7A 3H67A 2JOGA 1UTEA 4ORAA 3AV0A 4O24A 2ZBMA 2DFJA 4LU9A 1AUIA 2GJUA 2R17A 3JYFA 4ORCA 4DT2A 1QHWA 1M63A 3THNA 3DSCA 1XZWA 3K7WC 4F0ZA 4TUIA 1G5BA 1OI8A 2XMOA 3K7VC 1II7A 1HP1A 4LACC 4H2GA 2QJCA 3H62B 2NPPC 4KBPA 2BDXA 1S95A 1S3MA 3EGHA 4ORBA 4UT2A 3ZTVA 3V4YA 1S3NA 4I5LC 4J6OA 2ZO9B 2NYLC 4TUGA 2BQ8X 1USHA 3C9FA 4H2FA 4MOYA 4OR9A 4G9JA 4ZVZA 4I5NC 3IVEA 3ZU0A 3HVQA 4V0XA 2ZOAA 1IT6A 4MOVA 4XPNA 4H1YP 1Z2XA 4DSYA 3E0JA 3AUZA 1XM7A 2HY1A 2P6BA 1KBPA 3RQZA 4YKEA 4UT3A 1W24A 4M0VA 4FBKA 2WDFA 2Z1AA 1TCOA 2IE3C 2BCDA 4V0VA 2WDDA 3H66A 4MP0A 5GTUA 4WWLA 4JA9A 1S3LA 1T70A 3QFNA 3FGAC 1V73A 3RL3A 4O5GA 3P71C 3C5WC 3H61A 2HYPA 2Z06A 2Q8UA 3ICFA 2DXLA 1QFCA 1WARA 2YVTA 4H2IA 1Z2WA 2O8AA 2NXFA
chains in the Genus database with same CATH topology
4IL1A 4V0WA 3QFMA 2A22A 2IAEC 1U32A 3THOB 4O43A 5HPEA 1OIDA 3QG5C 5EQVA 5J28A 4NZVA 2IE4C 1MF8A 3IB8A 3DSDA 1JK7A 4H1SA 3PSOA 3E7AA 4UT3B 1T71A 4HD0A 3IB7A 3EGGA 2DXNA 3GVEA 3RL4A 4FCXA 4FBWA 5F3WA 2O8GA 3PSNA 3N5UA 3H64A 3RL5A 3D03A 4KKZA 1OIEA 3H68A 4UWQA 1S70A 1HPUA 4IYPC 4DHLA 5JPFA 5JPEA 4H2BA 3H63A 4ZX2A 3E7BA 2NYMC 2QFPA 3H69A 3KBPA 1FJMA 1SU1A 2AHDA 2YEQA 5JJTA 5IOHA 1UF3A 3H60A 3DW8C 2WDEA 4LTYA 3QFKA 3IVDA 3LL8A 5INBA 2USHA 2CV9A 2HYOA 3QFOA 4FBQA 3FLOA 1WAO1 2WDCA 4Q7FA 3TGHA 4O4KA 3CK2A 5B8IA 3T1IA 5DNYA 2QFRA 4B2OA 2KKNA 5C1VA 2Z72A 1S8EA 1NNWA 1HO5A 4JA7A 3H67A 2JOGA 1UTEA 4ORAA 3AV0A 4O24A 2ZBMA 2DFJA 4LU9A 1AUIA 2GJUA 2R17A 3JYFA 4ORCA 4DT2A 1QHWA 1M63A 3THNA 3DSCA 1XZWA 3K7WC 4F0ZA 4TUIA 1G5BA 1OI8A 2XMOA 3K7VC 1II7A 1HP1A 4LACC 4H2GA 2QJCA 3H62B 2NPPC 4KBPA 2BDXA 1S95A 1S3MA 3EGHA 4ORBA 4UT2A 3ZTVA 3V4YA 1S3NA 4I5LC 4J6OA 2ZO9B 2NYLC 4TUGA 2BQ8X 1USHA 3C9FA 4H2FA 4MOYA 4OR9A 4G9JA 4ZVZA 4I5NC 3IVEA 3ZU0A 3HVQA 4V0XA 2ZOAA 1IT6A 4MOVA 4XPNA 4H1YP 1Z2XA 4DSYA 3E0JA 3AUZA 1XM7A 2HY1A 2P6BA 1KBPA 3RQZA 4YKEA 4UT3A 1W24A 4M0VA 4FBKA 2WDFA 2Z1AA 1TCOA 2IE3C 2BCDA 4V0VA 2WDDA 3H66A 4MP0A 5GTUA 4WWLA 4JA9A 1S3LA 1T70A 3QFNA 3FGAC 1V73A 3RL3A 4O5GA 3P71C 3C5WC 3H61A 2HYPA 2Z06A 2Q8UA 3ICFA 2DXLA 1QFCA 1WARA 2YVTA 4H2IA 1Z2WA 2O8AA 2NXFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IL1 A;  4V0W A;  3QFM A;  2A22 A;  2IAE C;  1U32 A;  3THO B;  4O43 A;  5HPE A;  1OID A;  3QG5 C;  5EQV A;  5J28 A;  4NZV A;  2IE4 C;  1MF8 A;  3IB8 A;  3DSD A;  1JK7 A;  4H1S A;  3PSO A;  3E7A A;  4UT3 B;  1T71 A;  4HD0 A;  3IB7 A;  3EGG A;  3GVE A;  3RL4 A;  4FCX A;  4FBW A;  5F3W A;  2O8G A;  3PSN A;  3N5U A;  3H64 A;  3RL5 A;  4KKZ A;  1OIE A;  3H68 A;  4UWQ A;  1S70 A;  1HPU A;  4IYP C;  4DHL A;  5JPF A;  5JPE A;  4H2B A;  3H63 A;  4ZX2 A;  3E7B A;  2NYM C;  2QFP A;  3H69 A;  3KBP A;  1FJM A;  1SU1 A;  2AHD A;  5JJT A;  5IOH A;  1UF3 A;  3H60 A;  3DW8 C;  2WDE A;  4LTY A;  3QFK A;  3IVD A;  3LL8 A;  5INB A;  2USH A;  2CV9 A;  2HYO A;  3QFO A;  4FBQ A;  1WAO 1;  2WDC A;  4Q7F A;  3TGH A;  4O4K A;  3CK2 A;  5B8I A;  3T1I A;  5DNY A;  2QFR A;  4B2O A;  2KKN A;  5C1V A;  2Z72 A;  1S8E A;  1NNW A;  1HO5 A;  4JA7 A;  3H67 A;  2JOG A;  1UTE A;  4ORA A;  3AV0 A;  4O24 A;  2ZBM A;  2DFJ A;  4LU9 A;  1AUI A;  2GJU A;  2R17 A;  3JYF A;  4ORC A;  4DT2 A;  1QHW A;  1M63 A;  3THN A;  3DSC A;  1XZW A;  3K7W C;  4F0Z A;  4TUI A;  1G5B A;  1OI8 A;  2XMO A;  3K7V C;  1II7 A;  1HP1 A;  4LAC C;  4H2G A;  2QJC A;  3H62 B;  2NPP C;  4KBP A;  2BDX A;  1S95 A;  1S3M A;  3EGH A;  4ORB A;  4UT2 A;  3ZTV A;  3V4Y A;  1S3N A;  4I5L C;  4J6O A;  2NYL C;  4TUG A;  2BQ8 X;  1USH A;  3C9F A;  4H2F A;  4MOY A;  4OR9 A;  4G9J A;  4ZVZ A;  4I5N C;  3IVE A;  3ZU0 A;  3HVQ A;  4V0X A;  4MOV A;  1IT6 A;  4XPN A;  4H1Y P;  1Z2X A;  4DSY A;  3AUZ A;  1XM7 A;  2HY1 A;  2P6B A;  1KBP A;  3RQZ A;  4YKE A;  4UT3 A;  1W24 A;  4M0V A;  4FBK A;  2WDF A;  2Z1A A;  1TCO A;  2IE3 C;  2BCD A;  4V0V A;  2WDD A;  3H66 A;  4MP0 A;  5GTU A;  4WWL A;  4JA9 A;  1S3L A;  1T70 A;  3QFN A;  3FGA C;  1V73 A;  3RL3 A;  4O5G A;  3P71 C;  3C5W C;  3H61 A;  2HYP A;  2Z06 A;  2Q8U A;  3ICF A;  1QFC A;  1WAR A;  2YVT A;  4H2I A;  1Z2W A;  2O8A A;  2NXF A; 
#chains in the Genus database with same CATH topology
 4IL1 A;  4V0W A;  3QFM A;  2A22 A;  2IAE C;  1U32 A;  3THO B;  4O43 A;  5HPE A;  1OID A;  3QG5 C;  5EQV A;  5J28 A;  4NZV A;  2IE4 C;  1MF8 A;  3IB8 A;  3DSD A;  1JK7 A;  4H1S A;  3PSO A;  3E7A A;  4UT3 B;  1T71 A;  4HD0 A;  3IB7 A;  3EGG A;  2DXN A;  3GVE A;  3RL4 A;  4FCX A;  4FBW A;  5F3W A;  2O8G A;  3PSN A;  3N5U A;  3H64 A;  3RL5 A;  3D03 A;  4KKZ A;  1OIE A;  3H68 A;  4UWQ A;  1S70 A;  1HPU A;  4IYP C;  4DHL A;  5JPF A;  5JPE A;  4H2B A;  3H63 A;  4ZX2 A;  3E7B A;  2NYM C;  2QFP A;  3H69 A;  3KBP A;  1FJM A;  1SU1 A;  2AHD A;  2YEQ A;  5JJT A;  5IOH A;  1UF3 A;  3H60 A;  3DW8 C;  2WDE A;  4LTY A;  3QFK A;  3IVD A;  3LL8 A;  5INB A;  2USH A;  2CV9 A;  2HYO A;  3QFO A;  4FBQ A;  3FLO A;  1WAO 1;  2WDC A;  4Q7F A;  3TGH A;  4O4K A;  3CK2 A;  5B8I A;  3T1I A;  5DNY A;  2QFR A;  4B2O A;  2KKN A;  5C1V A;  2Z72 A;  1S8E A;  1NNW A;  1HO5 A;  4JA7 A;  3H67 A;  2JOG A;  1UTE A;  4ORA A;  3AV0 A;  4O24 A;  2ZBM A;  2DFJ A;  4LU9 A;  1AUI A;  2GJU A;  2R17 A;  3JYF A;  4ORC A;  4DT2 A;  1QHW A;  1M63 A;  3THN A;  3DSC A;  1XZW A;  3K7W C;  4F0Z A;  4TUI A;  1G5B A;  1OI8 A;  2XMO A;  3K7V C;  1II7 A;  1HP1 A;  4LAC C;  4H2G A;  2QJC A;  3H62 B;  2NPP C;  4KBP A;  2BDX A;  1S95 A;  1S3M A;  3EGH A;  4ORB A;  4UT2 A;  3ZTV A;  3V4Y A;  1S3N A;  4I5L C;  4J6O A;  2ZO9 B;  2NYL C;  4TUG A;  2BQ8 X;  1USH A;  3C9F A;  4H2F A;  4MOY A;  4OR9 A;  4G9J A;  4ZVZ A;  4I5N C;  3IVE A;  3ZU0 A;  3HVQ A;  4V0X A;  2ZOA A;  1IT6 A;  4MOV A;  4XPN A;  4H1Y P;  1Z2X A;  4DSY A;  3E0J A;  3AUZ A;  1XM7 A;  2HY1 A;  2P6B A;  1KBP A;  3RQZ A;  4YKE A;  4UT3 A;  1W24 A;  4M0V A;  4FBK A;  2WDF A;  2Z1A A;  1TCO A;  2IE3 C;  2BCD A;  4V0V A;  2WDD A;  3H66 A;  4MP0 A;  5GTU A;  4WWL A;  4JA9 A;  1S3L A;  1T70 A;  3QFN A;  3FGA C;  1V73 A;  3RL3 A;  4O5G A;  3P71 C;  3C5W C;  3H61 A;  2HYP A;  2Z06 A;  2Q8U A;  3ICF A;  2DXL A;  1QFC A;  1WAR A;  2YVT A;  4H2I A;  1Z2W A;  2O8A A;  2NXF A; 
#chains in the Genus database with same CATH homology
 4IL1 A;  4V0W A;  3QFM A;  2A22 A;  2IAE C;  1U32 A;  3THO B;  4O43 A;  5HPE A;  1OID A;  3QG5 C;  5EQV A;  5J28 A;  4NZV A;  2IE4 C;  1MF8 A;  3IB8 A;  3DSD A;  1JK7 A;  4H1S A;  3PSO A;  3E7A A;  4UT3 B;  1T71 A;  4HD0 A;  3IB7 A;  3EGG A;  2DXN A;  3GVE A;  3RL4 A;  4FCX A;  4FBW A;  5F3W A;  2O8G A;  3PSN A;  3N5U A;  3H64 A;  3RL5 A;  3D03 A;  4KKZ A;  1OIE A;  3H68 A;  4UWQ A;  1S70 A;  1HPU A;  4IYP C;  4DHL A;  5JPF A;  5JPE A;  4H2B A;  3H63 A;  4ZX2 A;  3E7B A;  2NYM C;  2QFP A;  3H69 A;  3KBP A;  1FJM A;  1SU1 A;  2AHD A;  2YEQ A;  5JJT A;  5IOH A;  1UF3 A;  3H60 A;  3DW8 C;  2WDE A;  4LTY A;  3QFK A;  3IVD A;  3LL8 A;  5INB A;  2USH A;  2CV9 A;  2HYO A;  3QFO A;  4FBQ A;  3FLO A;  1WAO 1;  2WDC A;  4Q7F A;  3TGH A;  4O4K A;  3CK2 A;  5B8I A;  3T1I A;  5DNY A;  2QFR A;  4B2O A;  2KKN A;  5C1V A;  2Z72 A;  1S8E A;  1NNW A;  1HO5 A;  4JA7 A;  3H67 A;  2JOG A;  1UTE A;  4ORA A;  3AV0 A;  4O24 A;  2ZBM A;  2DFJ A;  4LU9 A;  1AUI A;  2GJU A;  2R17 A;  3JYF A;  4ORC A;  4DT2 A;  1QHW A;  1M63 A;  3THN A;  3DSC A;  1XZW A;  3K7W C;  4F0Z A;  4TUI A;  1G5B A;  1OI8 A;  2XMO A;  3K7V C;  1II7 A;  1HP1 A;  4LAC C;  4H2G A;  2QJC A;  3H62 B;  2NPP C;  4KBP A;  2BDX A;  1S95 A;  1S3M A;  3EGH A;  4ORB A;  4UT2 A;  3ZTV A;  3V4Y A;  1S3N A;  4I5L C;  4J6O A;  2ZO9 B;  2NYL C;  4TUG A;  2BQ8 X;  1USH A;  3C9F A;  4H2F A;  4MOY A;  4OR9 A;  4G9J A;  4ZVZ A;  4I5N C;  3IVE A;  3ZU0 A;  3HVQ A;  4V0X A;  2ZOA A;  1IT6 A;  4MOV A;  4XPN A;  4H1Y P;  1Z2X A;  4DSY A;  3E0J A;  3AUZ A;  1XM7 A;  2HY1 A;  2P6B A;  1KBP A;  3RQZ A;  4YKE A;  4UT3 A;  1W24 A;  4M0V A;  4FBK A;  2WDF A;  2Z1A A;  1TCO A;  2IE3 C;  2BCD A;  4V0V A;  2WDD A;  3H66 A;  4MP0 A;  5GTU A;  4WWL A;  4JA9 A;  1S3L A;  1T70 A;  3QFN A;  3FGA C;  1V73 A;  3RL3 A;  4O5G A;  3P71 C;  3C5W C;  3H61 A;  2HYP A;  2Z06 A;  2Q8U A;  3ICF A;  2DXL A;  1QFC A;  1WAR A;  2YVT A;  4H2I A;  1Z2W A;  2O8A A;  2NXF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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